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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:microcystin
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Accession:CHEBI:48041 term browser browse the term
Definition:A family of cyclic heptapeptide hepatotoxins produced by a number of cyanobacteria, the most notable of which is Microcystis, from which the name of the family is derived. Microcystins consist of a heptapeptide macrocycle made up of five non-protein amino acids and two protein amino acids.
Synonyms:related_synonym: microcystins
 alt_id: MESH:D052998
 xref_mesh: MESH:D052998
 xref: MetaCyc:Microcystins;   Wikipedia:Microcystin


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microcystin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 increases expression EXP Microcystins results in increased expression of ACTG1 protein CTD PMID:22430071 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Alb albumin increases expression EXP Microcystins results in increased expression of ALB protein CTD PMID:22430071 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression EXP Microcystins results in decreased expression of ALDH9A1 protein CTD PMID:22430071 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression EXP Microcystins results in decreased expression of ATP6V1B2 protein CTD PMID:22430071 NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
EXP Microcystins results in increased expression of BAX mRNA; Microcystins results in increased expression of BAX protein
microcystin results in decreased expression of BAX
CTD PMID:12411203, PMID:19760617 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
EXP Microcystins results in decreased expression of BCL2 mRNA; Microcystins results in decreased expression of BCL2 protein
microcystin results in increased expression of BCL2
CTD PMID:12411203, PMID:19760617 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 increases expression EXP Microcystins results in increased expression of CAPZA2 protein CTD PMID:22430071 NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
JBrowse link
G Cat catalase increases expression EXP microcystin results in increased expression of CAT mRNA; microcystin results in increased expression of CAT protein CTD PMID:19135122 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Dpp3 dipeptidylpeptidase 3 increases expression EXP Microcystins results in increased expression of DPP3 protein CTD PMID:22430071 NCBI chr 1:220,166,124...220,189,762
Ensembl chr 1:220,166,127...220,188,541
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression EXP Microcystins results in increased expression of DYNC1I1 protein CTD PMID:22430071 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
EXP Microcystins analog results in increased expression of GCLC mRNA
Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in increased expression of GCLC mRNA]
CTD PMID:24964298 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 increases expression EXP Microcystins results in increased expression of GDI1 protein CTD PMID:22430071 NCBI chr  X:156,400,734...156,407,396
Ensembl chr  X:156,400,736...156,407,404
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases degradation
EXP Microcystins results in decreased expression of GFAP protein
microcystin analog results in increased degradation of GFAP protein
CTD PMID:22430071, PMID:27864109 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Golga3 golgin A3 decreases expression EXP Microcystins results in decreased expression of GOLGA3 protein CTD PMID:22430071 NCBI chr12:52,510,509...52,558,606
Ensembl chr12:52,512,970...52,558,606
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
EXP microcystin results in increased expression of GPX1 mRNA; Microcystins analog results in increased expression of GPX1 mRNA
Buthionine Sulfoximine promotes the reaction [Microcystins analog results in increased expression of GPX1 mRNA]
CTD PMID:19135122, PMID:24964298 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression EXP Microcystins results in decreased expression of GRB2 protein CTD PMID:22430071 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
EXP Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in decreased expression of GSR mRNA] CTD PMID:24964298 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression
increases expression
EXP Microcystins results in decreased expression of GSTA3 mRNA
Microcystins results in increased expression of GSTA3 mRNA
CTD PMID:19790251 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression
increases expression
EXP Microcystins results in decreased expression of GSTA4 mRNA
microcystin results in increased expression of GSTA4 mRNA; Microcystins results in increased expression of GSTA4 mRNA
CTD PMID:19135122, PMID:19790251 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 affects expression
increases expression
EXP Microcystins affects the expression of GSTK1 mRNA
Microcystins results in increased expression of GSTK1 mRNA
CTD PMID:19790251 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression EXP Microcystins affects the expression of GSTM1 mRNA CTD PMID:19790251 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression
increases expression
EXP Microcystins results in decreased expression of GSTM2 mRNA
Microcystins results in increased expression of GSTM2 mRNA
CTD PMID:19790251 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 affects expression
decreases expression
EXP Microcystins affects the expression of GSTM3 mRNA
Microcystins results in decreased expression of GSTM3 mRNA
CTD PMID:19790251 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gsto1 glutathione S-transferase omega 1 affects expression
decreases expression
EXP Microcystins affects the expression of GSTO1 mRNA
Microcystins results in decreased expression of GSTO1 mRNA
CTD PMID:19790251 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gsto2 glutathione S-transferase omega 2 affects expression EXP Microcystins affects the expression of GSTO2 mRNA CTD PMID:19790251 NCBI chr 1:267,617,517...267,640,455
Ensembl chr 1:271,229,036...271,243,517
Ensembl chr 1:271,229,036...271,243,517
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
affects expression
EXP Buthionine Sulfoximine inhibits the reaction [Microcystins analog results in increased expression of GSTP1 mRNA]
Microcystins analog results in increased expression of GSTP1 mRNA; Microcystins results in increased expression of GSTP1 mRNA
Microcystins affects the expression of GSTP1 mRNA
CTD PMID:19790251, PMID:24964298 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression
increases expression
EXP Microcystins affects the expression of GSTT1 mRNA
Microcystins results in increased expression of GSTT1 mRNA
CTD PMID:19790251 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression
affects expression
EXP Microcystins results in decreased expression of GSTT2 mRNA
Microcystins affects the expression of GSTT2 mRNA
CTD PMID:19790251 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression
affects expression
EXP Microcystins results in decreased expression of GSTZ1 mRNA
Microcystins affects the expression of GSTZ1 mRNA
CTD PMID:19790251 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Microcystins results in increased expression of HSPA5 protein CTD PMID:22430071 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression EXP Microcystins results in increased expression of INA mRNA; Microcystins results in increased expression of INA protein CTD PMID:22430071 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Microcystins results in increased expression of LASP1 protein CTD PMID:22430071 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation EXP Microcystins results in increased phosphorylation of MAPT protein CTD PMID:22430071 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 affects expression
increases expression
EXP Microcystins affects the expression of MGST1 mRNA
Microcystins results in increased expression of MGST1 mRNA
CTD PMID:19790251 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mtus2 microtubule associated scaffold protein 2 increases expression EXP Microcystins results in increased expression of MTUS2 protein CTD PMID:22430071 NCBI chr12:8,111,655...8,491,553
Ensembl chr12:8,111,667...8,418,966
JBrowse link
G Myl2 myosin light chain 2 increases expression EXP Microcystins results in increased expression of MYL2 protein CTD PMID:22430071 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation EXP microcystin results in increased phosphorylation of MYL9 protein CTD PMID:18835913 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 increases expression EXP Microcystins results in increased expression of NECAB1 protein CTD PMID:22430071 NCBI chr 5:28,507,596...28,737,556
Ensembl chr 5:28,504,558...28,737,719
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP Microcystins results in decreased expression of PDIA3 protein CTD PMID:22430071 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdxp pyridoxal phosphatase decreases expression EXP Microcystins results in decreased expression of PDXP protein CTD PMID:22430071 NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Microcystins results in decreased expression of PPP1CC protein CTD PMID:22430071 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases expression EXP Microcystins results in increased expression of PPP1R1B protein CTD PMID:22430071 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP Microcystins results in increased expression of PRDX2 protein CTD PMID:22430071 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP Microcystins results in increased expression of RPSA protein CTD PMID:22430071 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) increases expression EXP Microcystins results in increased expression of SEMA7A protein CTD PMID:22430071 NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
JBrowse link
G Septin11 septin 11 increases expression
decreases expression
EXP Microcystins results in increased expression of SEPTIN11 protein
Microcystins results in decreased expression of SEPTIN11 protein
CTD PMID:22430071 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
JBrowse link
G Septin5 septin 5 increases expression EXP Microcystins results in increased expression of SEPTIN5 mRNA; Microcystins results in increased expression of SEPTIN5 protein CTD PMID:22430071 NCBI chr11:86,516,377...86,522,169
Ensembl chr11:86,512,797...86,522,168
JBrowse link
G Septin8 septin 8 increases expression EXP Microcystins results in increased expression of SEPTIN8 protein CTD PMID:22430071 NCBI chr10:38,877,422...38,906,480
Ensembl chr10:38,877,422...38,906,482
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases uptake
increases response to substance
ISO SLCO1B2 protein results in increased uptake of Microcystins
SLCO1B3 protein results in increased uptake of Microcystins
SLCO1B3 protein results in increased susceptibility to microcystin analog
CTD PMID:20171238, PMID:20472527 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Snca synuclein alpha increases expression EXP Microcystins results in increased expression of SNCA mRNA; Microcystins results in increased expression of SNCA protein CTD PMID:22430071 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP Microcystins results in increased expression of SOD1 protein CTD PMID:22430071 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP microcystin results in increased expression of SOD2 mRNA CTD PMID:19135122 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression EXP Microcystins results in increased expression of STIP1 protein CTD PMID:22430071 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Tmod2 tropomodulin 2 decreases expression EXP Microcystins results in decreased expression of TMOD2 protein CTD PMID:22430071 NCBI chr 8:82,505,947...82,547,450
Ensembl chr 8:82,506,934...82,533,689
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP microcystin results in increased expression of TNNI3 protein CTD PMID:19135122 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Microcystins results in increased expression of TP53 mRNA; Microcystins results in increased expression of TP53 protein CTD PMID:19760617 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Microcystins results in increased expression of TPI1 protein CTD PMID:22430071 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Microcystins results in increased expression of TPM1 protein CTD PMID:22430071 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Trap1 TNF receptor-associated protein 1 increases expression EXP Microcystins results in increased expression of TRAP1 protein CTD PMID:22430071 NCBI chr10:11,724,032...11,757,682
Ensembl chr10:11,724,032...11,757,681
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Microcystins results in decreased expression of TUBA1C protein CTD PMID:22430071 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tubb2b tubulin, beta 2B class IIb decreases expression EXP Microcystins results in decreased expression of TUBB2B protein CTD PMID:22430071 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759
JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Microcystins results in decreased expression of TUBB4B protein CTD PMID:22430071 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial increases expression EXP Microcystins results in increased expression of TUFM protein CTD PMID:22430071 NCBI chr 1:197,903,582...197,907,189
Ensembl chr 1:197,903,582...197,907,189
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression EXP Microcystins results in decreased expression of UCHL3 protein CTD PMID:22430071 NCBI chr15:86,153,624...86,198,127
Ensembl chr15:86,153,628...86,198,127
JBrowse link
microcystin LF term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export
multiple interactions
ISO ABCC2 protein results in increased export of microcystin-LF
microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:31348918 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Gfap glial fibrillary acidic protein increases degradation EXP microcystin-LF results in increased degradation of GFAP protein CTD PMID:27864109 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Mapt microtubule-associated protein tau affects phosphorylation ISO microcystin-LF affects the phosphorylation of MAPT protein CTD PMID:21934130 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases response to substance ISO SLCO1B3 protein results in increased susceptibility to microcystin-LF CTD PMID:20171238 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
microcystin RR term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export
multiple interactions
ISO ABCC2 protein results in increased export of microcystin RR
microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:31348918 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Ace angiotensin I converting enzyme increases expression ISO microcystin RR results in increased expression of ACE mRNA; microcystin RR results in increased expression of ACE protein CTD PMID:28330766 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen increases expression
multiple interactions
ISO microcystin RR results in increased expression of AGT mRNA; microcystin RR results in increased expression of AGT protein
aliskiren inhibits the reaction [microcystin RR results in increased expression of AGT protein]
CTD PMID:28330766 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression ISO microcystin RR results in increased expression of AHSA1 protein CTD PMID:19111056 NCBI chr 6:111,296,168...111,304,224
Ensembl chr 6:111,296,417...111,304,224
JBrowse link
G Alb albumin decreases expression ISO microcystin RR results in decreased expression of ALB protein CTD PMID:28330766 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 decreases expression ISO microcystin RR results in decreased expression of ARPC5 protein CTD PMID:19111056 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression ISO microcystin RR results in decreased expression of ATP5PD protein CTD PMID:19111056 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Avp arginine vasopressin increases expression ISO microcystin RR results in increased expression of AVP protein CTD PMID:28330766 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO microcystin RR results in increased expression of BAX protein CTD PMID:20196164 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO microcystin RR results in decreased expression of BCL2 protein CTD PMID:20196164 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G C1qbp complement C1q binding protein decreases expression ISO microcystin RR results in decreased expression of C1QBP protein CTD PMID:19111056 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO microcystin RR results in decreased expression of CAPZA1 protein CTD PMID:19111056 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Ccdc18 coiled-coil domain containing 18 increases expression ISO microcystin RR results in increased expression of CCDC18 protein CTD PMID:19111056 NCBI chr14:1,664,620...1,701,269
NCBI chr14:2,510,184...2,612,070
Ensembl chr14:2,509,363...2,610,929
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression ISO microcystin RR results in increased expression of CCT8 protein CTD PMID:19111056 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO microcystin RR results in decreased expression of CDK4 protein CTD PMID:19111056 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO microcystin RR results in decreased expression of CDKN2A protein CTD PMID:19111056 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression ISO microcystin RR results in increased expression of CIAPIN1 protein CTD PMID:19111056 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO microcystin RR results in increased expression of CLIC4 protein CTD PMID:19111056 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO microcystin RR results in decreased expression of COX5A protein CTD PMID:19111056 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein increases expression ISO microcystin RR results in increased expression of CRKL protein CTD PMID:19111056 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Csde1 cold shock domain containing E1 increases expression ISO microcystin RR results in increased expression of CSDE1 protein CTD PMID:19111056 NCBI chr 2:205,525,194...205,552,987
Ensembl chr 2:205,525,204...205,552,991
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression ISO microcystin RR results in decreased expression of ECHS1 protein CTD PMID:19111056 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma increases expression ISO microcystin RR results in increased expression of EIF2B3 protein CTD PMID:19111056 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO microcystin RR results in increased expression of EIF5A protein CTD PMID:19111056 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO microcystin RR results in decreased expression of ERCC1 protein CTD PMID:19111056 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression ISO microcystin RR results in decreased expression of ERP29 protein CTD PMID:19111056 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esd esterase D decreases expression ISO microcystin RR results in decreased expression of ESD protein CTD PMID:19111056 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO microcystin RR results in decreased expression of FABP5 protein CTD PMID:19111056 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Flot1 flotillin 1 increases expression ISO microcystin RR results in increased expression of FLOT1 protein CTD PMID:19111056 NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases expression ISO microcystin RR results in increased expression of G3BP1 protein CTD PMID:19111056 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G Galnt13 polypeptide N-acetylgalactosaminyltransferase 13 decreases expression ISO microcystin RR results in decreased expression of GALNT13 protein CTD PMID:19111056 NCBI chr 3:39,967,056...40,625,144
Ensembl chr 3:40,038,336...40,624,530
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity ISO microcystin RR results in increased activity of GPT protein CTD PMID:28330766 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases glutathionylation ISO GSTA1 protein results in increased glutathionylation of microcystin RR CTD PMID:23538035 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases glutathionylation ISO GSTM1 protein results in increased glutathionylation of microcystin RR CTD PMID:23538035 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases glutathionylation ISO GSTP1 protein results in increased glutathionylation of microcystin RR CTD PMID:23538035 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases glutathionylation ISO GSTT1 protein results in increased glutathionylation of microcystin RR CTD PMID:23538035 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO microcystin RR results in increased expression of HSPA1B protein CTD PMID:19111056 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO microcystin RR results in increased expression of HSPA5 protein CTD PMID:20196164 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hypk Huntingtin interacting protein K decreases expression ISO microcystin RR results in decreased expression of HYPK protein CTD PMID:19111056 NCBI chr 3:113,423,684...113,425,064
Ensembl chr 3:113,423,693...113,424,846
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression ISO microcystin RR results in increased expression of IDH3A protein CTD PMID:19111056 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Immt inner membrane mitochondrial protein increases expression
decreases expression
ISO microcystin RR results in increased expression of IMMT protein
microcystin RR results in decreased expression of IMMT protein
CTD PMID:19111056 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO microcystin RR results in increased expression of IMPDH2 protein CTD PMID:19111056 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO microcystin RR results in increased expression of KPNA4 protein CTD PMID:19111056 NCBI chr 2:165,684,345...165,739,874
Ensembl chr 2:165,684,345...165,739,874
JBrowse link
G Krt10 keratin 10 increases expression
decreases expression
ISO microcystin RR results in increased expression of KRT10 protein
microcystin RR results in decreased expression of KRT10 protein
CTD PMID:19111056 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt2 keratin 2 decreases expression ISO microcystin RR results in decreased expression of KRT2 protein CTD PMID:19111056 NCBI chr 7:143,412,858...143,420,463
Ensembl chr 7:143,412,858...143,420,027
JBrowse link
G Ldhc lactate dehydrogenase C decreases expression ISO microcystin RR results in decreased expression of LDHC protein CTD PMID:19111056 NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
JBrowse link
G Lgals1 galectin 1 decreases expression ISO microcystin RR results in decreased expression of LGALS1 protein CTD PMID:19111056 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lmna lamin A/C increases expression ISO microcystin RR results in increased expression of LMNA protein CTD PMID:19111056 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 increases expression ISO microcystin RR results in increased expression of MACF1 protein CTD PMID:19111056 NCBI chr 5:141,039,455...141,363,524
Ensembl chr 5:141,039,468...141,363,524
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression
increases expression
ISO microcystin RR results in decreased expression of MCM7 protein
microcystin RR results in increased expression of MCM7 protein
CTD PMID:19111056 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 decreases expression ISO microcystin RR results in decreased expression of MRPS22 protein CTD PMID:19111056 NCBI chr 8:106,604,421...106,617,591
Ensembl chr 8:106,604,379...106,617,597
JBrowse link
G Napg NSF attachment protein gamma decreases expression ISO microcystin RR results in decreased expression of NAPG protein CTD PMID:19111056 NCBI chr18:58,325,319...58,344,071
Ensembl chr18:58,325,319...58,344,070
JBrowse link
G Naxe NAD(P)HX epimerase decreases expression ISO microcystin RR results in decreased expression of NAXE protein CTD PMID:19111056 NCBI chr 2:187,424,319...187,426,410
Ensembl chr 2:187,424,327...187,426,375
JBrowse link
G Nit2 nitrilase family, member 2 decreases expression ISO microcystin RR results in decreased expression of NIT2 protein CTD PMID:19111056 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Nutf2 nuclear transport factor 2 decreases expression ISO microcystin RR results in decreased expression of NUTF2 protein CTD PMID:19111056 NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
JBrowse link
G Pdcd6 programmed cell death 6 decreases expression ISO microcystin RR results in decreased expression of PDCD6 protein CTD PMID:19111056 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO microcystin RR results in increased expression of PDIA3 protein CTD PMID:19111056 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression ISO microcystin RR results in decreased expression of PGAM1 protein CTD PMID:19111056 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Phpt1 phosphohistidine phosphatase 1 decreases expression ISO microcystin RR results in decreased expression of PHPT1 protein CTD PMID:19111056 NCBI chr 3:2,797,037...2,798,436
Ensembl chr 3:2,796,997...2,798,470
JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta increases expression ISO microcystin RR results in increased expression of PMPCB protein CTD PMID:19111056 NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610
JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression ISO microcystin RR results in decreased expression of PNP protein CTD PMID:19111056 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases expression
decreases expression
ISO microcystin RR results in increased expression of PPA1 protein
microcystin RR results in decreased expression of PPA1 protein
CTD PMID:19111056 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression ISO microcystin RR results in increased expression of PPP2R1A protein CTD PMID:19111056 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta increases expression ISO microcystin RR results in increased expression of PPP2R5B protein CTD PMID:19111056 NCBI chr 1:221,597,294...221,605,467
Ensembl chr 1:221,597,296...221,605,400
JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 increases expression
decreases expression
ISO microcystin RR results in increased expression of PRPS2 protein
microcystin RR results in decreased expression of PRPS2 protein
CTD PMID:19111056 NCBI chr  X:28,435,275...28,472,882
Ensembl chr  X:28,435,507...28,472,880
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression ISO microcystin RR results in increased expression of PSMA1 protein CTD PMID:19111056 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 decreases expression ISO microcystin RR results in decreased expression of PSMB2 protein CTD PMID:19111056 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression ISO microcystin RR results in increased expression of PSMB3 protein CTD PMID:19111056 NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 decreases expression ISO microcystin RR results in decreased expression of PSMB4 protein CTD PMID:19111056 NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 decreases expression ISO microcystin RR results in decreased expression of PSMB6 protein CTD PMID:19111056 NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression ISO microcystin RR results in decreased expression of PSMB9 protein CTD PMID:19111056 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 decreases expression ISO microcystin RR results in decreased expression of PSMD10 protein CTD PMID:19111056 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression ISO microcystin RR results in increased expression of PSME1 protein CTD PMID:19111056 NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
JBrowse link
G Rab14 RAB14, member RAS oncogene family increases expression ISO microcystin RR results in increased expression of RAB14 protein CTD PMID:19111056 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rfc5 replication factor C subunit 5 increases expression ISO microcystin RR results in increased expression of RFC5 protein CTD PMID:19111056 NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
JBrowse link
G Septin11 septin 11 increases expression ISO microcystin RR results in increased expression of SEPTIN11 protein CTD PMID:19111056 NCBI chr14:16,369,544...16,405,645
Ensembl chr14:16,369,544...16,452,998
JBrowse link
G Septin2 septin 2 increases expression ISO microcystin RR results in increased expression of SEPTIN2 protein CTD PMID:19111056 NCBI chr 9:100,624,876...100,658,053
Ensembl chr 9:100,624,876...100,658,050
JBrowse link
G Serpinb5 serpin family B member 5 decreases expression ISO microcystin RR results in decreased expression of SERPINB5 protein CTD PMID:19111056 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO microcystin RR results in decreased expression of SOD1 protein CTD PMID:19111056 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO microcystin RR results in decreased expression of TALDO1 protein CTD PMID:19111056 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tbca tubulin folding cofactor A decreases expression ISO microcystin RR results in decreased expression of TBCA protein CTD PMID:19111056 NCBI chr 2:24,449,498...24,505,351
Ensembl chr 2:24,449,485...24,505,334
JBrowse link
G Tbcb tubulin folding cofactor B increases expression ISO microcystin RR results in increased expression of TBCB protein CTD PMID:19111056 NCBI chr 1:88,680,936...88,686,785
Ensembl chr 1:88,680,856...88,686,615
JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 decreases expression ISO microcystin RR results in decreased expression of TIMM50 protein CTD PMID:19111056 NCBI chr 1:85,470,810...85,480,813
Ensembl chr 1:85,470,831...85,480,407
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO microcystin RR results in decreased expression of TNFRSF25 protein CTD PMID:19111056 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tp53 tumor protein p53 increases expression ISO microcystin RR results in increased expression of TP53 protein
microcystin RR results in increased expression of TRP53 protein
CTD PMID:19111056, PMID:20196164 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm4 tropomyosin 4 decreases expression ISO microcystin RR results in decreased expression of TPM4 protein CTD PMID:19111056 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Trpc7 transient receptor potential cation channel, subfamily C, member 7 increases expression ISO microcystin RR results in increased expression of TRPC7 protein CTD PMID:19111056 NCBI chr17:8,134,267...8,280,360
Ensembl chr17:8,135,251...8,279,515
JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO microcystin RR results in decreased expression of TXN protein CTD PMID:19111056 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnl1 thioredoxin-like 1 decreases expression ISO microcystin RR results in decreased expression of TXNL1 protein CTD PMID:19111056 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 increases expression ISO microcystin RR results in increased expression of UFD1 protein CTD PMID:19111056 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Vcl vinculin decreases expression
increases expression
ISO microcystin RR results in decreased expression of VCL protein
microcystin RR results in increased expression of VCL protein
CTD PMID:19111056 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma decreases expression ISO microcystin RR results in decreased expression of YWHAG protein CTD PMID:19111056 NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
JBrowse link
G Zfp951 zinc finger protein 951 increases expression ISO microcystin RR results in increased expression of ZNF57 protein CTD PMID:19111056 NCBI chr14:6,280,767...6,284,145
Ensembl chr14:6,281,336...6,284,145
Ensembl chr14:6,281,336...6,284,145
JBrowse link
microcystin-LR term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 increases expression ISO cyanoginosin LR results in increased expression of ABCA8B mRNA CTD PMID:17654400 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcb10 ATP binding cassette subfamily B member 10 decreases expression ISO cyanoginosin LR results in decreased expression of ABCB10 mRNA CTD PMID:17654400 NCBI chr19:56,742,809...56,772,904
Ensembl chr19:56,742,835...56,772,904
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO cyanoginosin LR results in increased expression of ABCB1A mRNA CTD PMID:17654400 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
increases export
multiple interactions
ISO cyanoginosin LR results in increased expression of ABCC2 mRNA
ABCC2 protein results in increased export of cyanoginosin LR
cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:17654400, PMID:31348918 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO cyanoginosin LR results in increased expression of ABCC5 mRNA CTD PMID:17654400 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO cyanoginosin LR results in decreased expression of ACAA1 protein CTD PMID:26984711 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO cyanoginosin LR results in decreased expression of ACACA protein CTD PMID:26984711 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acad10 acyl-CoA dehydrogenase family, member 10 decreases expression ISO cyanoginosin LR results in decreased expression of ACAD10 protein CTD PMID:26984711 NCBI chr12:40,417,918...40,460,562
Ensembl chr12:40,417,944...40,460,561
JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 decreases expression ISO cyanoginosin LR results in decreased expression of ACAD11 protein CTD PMID:26984711 NCBI chr 8:112,594,758...112,676,275
Ensembl chr 8:112,594,691...112,676,280
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO cyanoginosin LR results in decreased expression of ACADL protein CTD PMID:26984711 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO cyanoginosin LR results in decreased expression of ACADM protein CTD PMID:26984711 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO cyanoginosin LR results in decreased expression of ACADVL protein CTD PMID:26984711 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects expression ISO cyanoginosin LR affects the expression of ACAT2 protein CTD PMID:26984711 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl decreases expression ISO cyanoginosin LR results in decreased expression of ACOX3 protein CTD PMID:26984711 NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
JBrowse link
G Actb actin, beta decreases expression ISO
EXP
cyanoginosin LR results in decreased expression of ACTB mRNA CTD PMID:17383702, PMID:23342045 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Afm afamin decreases expression ISO cyanoginosin LR results in decreased expression of AFM mRNA CTD PMID:17654400 NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO cyanoginosin LR results in increased expression of AKR1B3 mRNA CTD PMID:17654400 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
decreases expression
multiple interactions
ISO cyanoginosin LR results in increased phosphorylation of AKT1 protein
cyanoginosin LR results in decreased expression of AKT1 mRNA; cyanoginosin LR results in decreased expression of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of AKT1 protein]
CTD PMID:26506538, PMID:29777831, PMID:31714646, PMID:32073747 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases expression ISO cyanoginosin LR results in decreased expression of AKT3 mRNA; cyanoginosin LR results in decreased expression of AKT3 protein CTD PMID:28414124, PMID:29518473 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Alb albumin decreases expression
increases secretion
ISO cyanoginosin LR results in decreased expression of ALB mRNA; cyanoginosin LR results in decreased expression of ALB protein
cyanoginosin LR results in increased secretion of ALB protein
CTD PMID:17654400, PMID:17654404, PMID:26984711 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of ALDH1L1 protein CTD PMID:18000846 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO cyanoginosin LR results in decreased expression of ALPI mRNA CTD PMID:29518473 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Alyref Aly/REF export factor decreases expression ISO cyanoginosin LR results in decreased expression of THOC4 protein CTD PMID:26984711 NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
JBrowse link
G Anxa2 annexin A2 increases expression ISO cyanoginosin LR results in increased expression of ANXA2 mRNA CTD PMID:17654400 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa4 annexin A4 increases expression ISO cyanoginosin LR results in increased expression of ANXA4 mRNA CTD PMID:17654400 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 increases expression ISO cyanoginosin LR results in increased expression of ANXA5 mRNA CTD PMID:17654400 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa7 annexin A7 increases expression ISO cyanoginosin LR results in increased expression of ANXA7 mRNA CTD PMID:17654400 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO cyanoginosin LR results in increased expression of APEX1 mRNA CTD PMID:17654400 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO cyanoginosin LR results in increased expression of APOA1 protein CTD PMID:26984711 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B affects expression ISO cyanoginosin LR affects the expression of APOB protein CTD PMID:26984711 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc3 apolipoprotein C3 affects expression ISO cyanoginosin LR affects the expression of APOC3 protein CTD PMID:26984711 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E increases expression ISO cyanoginosin LR results in increased expression of APOE protein CTD PMID:26984711 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ar androgen receptor affects expression ISO cyanoginosin LR affects the expression of AR mRNA; cyanoginosin LR affects the expression of AR protein CTD PMID:28189720 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO cyanoginosin LR results in increased expression of ARHGEF2 mRNA CTD PMID:17654400 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO cyanoginosin LR results in increased expression of ASNS mRNA CTD PMID:17654400 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression ISO cyanoginosin LR results in decreased expression of ASS1 mRNA CTD PMID:17383702 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf2 activating transcription factor 2 increases expression ISO cyanoginosin LR results in increased expression of ATF2 protein modified form CTD PMID:27393157 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression ISO cyanoginosin LR results in increased expression of ATOX1 mRNA CTD PMID:17654400 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of BAD protein CTD PMID:26506538, PMID:27352821 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO
EXP
cyanoginosin LR results in increased expression of BAX mRNA; cyanoginosin LR results in increased expression of BAX protein CTD PMID:17654400, PMID:18214937, PMID:22539157, PMID:23891578, PMID:25410294, PMID:28414124, PMID:31157505, PMID:32142839 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
EXP pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of BBC3 protein] CTD PMID:31157505 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
increases phosphorylation
multiple interactions
ISO
EXP
cyanoginosin LR results in increased expression of BCL2
cyanoginosin LR results in decreased expression of BCL2 protein
cyanoginosin LR results in increased phosphorylation of BCL2 protein
cyanoginosin LR results in increased expression of and results in increased phosphorylation of BCL2 protein
Buthionine Sulfoximine promotes the reaction [cyanoginosin LR results in decreased expression of BCL2 protein]
CTD PMID:16624733, PMID:18214937, PMID:23891578, PMID:25410294, PMID:26506538, PMID:27352821, PMID:32142839 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO cyanoginosin LR results in increased expression of BCL2L11 mRNA CTD PMID:17654400 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO cyanoginosin LR results in increased expression of BIRC3 protein CTD PMID:22539157 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO cyanoginosin LR results in increased expression of BLVRB mRNA CTD PMID:17654400 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bmp5 bone morphogenetic protein 5 increases expression ISO cyanoginosin LR results in increased expression of BMP5 mRNA CTD PMID:29518473 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO cyanoginosin LR results in decreased expression of BSG mRNA CTD PMID:17383702 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G C9 complement C9 decreases expression ISO cyanoginosin LR results in decreased expression of C9 mRNA CTD PMID:17383702 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 increases expression ISO cyanoginosin LR results in increased expression of CABLES1 mRNA CTD PMID:29518473 NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
JBrowse link
G Calm2 calmodulin 2 increases expression ISO cyanoginosin LR results in increased expression of CALM2 mRNA CTD PMID:17654400 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 increases expression ISO cyanoginosin LR results in increased expression of CALM3 mRNA CTD PMID:17654400 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I increases expression ISO cyanoginosin LR results in increased expression of CAMK1 mRNA CTD PMID:17654400 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Capn2 calpain 2 increases expression ISO cyanoginosin LR results in increased expression of CAPN2 mRNA CTD PMID:17654400 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Capns1 calpain, small subunit 1 increases expression ISO cyanoginosin LR results in increased expression of CAPNS1 mRNA CTD PMID:17654400 NCBI chr 1:91,058,528...91,064,880 JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta increases expression ISO cyanoginosin LR results in increased expression of CAPZB mRNA CTD PMID:17654400 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions
increases expression
ISO
EXP
cyanoginosin LR results in increased activity of CASP3 protein
cyanoginosin LR results in increased cleavage of CASP3 protein
pifithrin inhibits the reaction [cyanoginosin LR results in increased cleavage of CASP3 protein]
cyanoginosin LR results in increased expression of CASP3 mRNA
cyanoginosin LR results in increased expression of CASP3 mRNA; cyanoginosin LR results in increased expression of CASP3 protein
sulforafan inhibits the reaction [cyanoginosin LR results in increased activity of CASP3 protein]
CTD PMID:21684301, PMID:22539157, PMID:23454832, PMID:23891578, PMID:28414124, PMID:31157505, PMID:32142839 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO cyanoginosin LR results in increased expression of CASP8 mRNA; cyanoginosin LR results in increased expression of CASP8 protein CTD PMID:23454832, PMID:23891578 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression ISO cyanoginosin LR results in increased expression of CASP9 protein CTD PMID:23454832 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression ISO cyanoginosin LR results in increased expression of CAST mRNA CTD PMID:17654400 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase decreases expression
multiple interactions
decreases activity
increases activity
ISO cyanoginosin LR results in decreased expression of CAT mRNA
GCLC protein inhibits the reaction [cyanoginosin LR results in decreased activity of CAT protein]
cyanoginosin LR results in increased activity of CAT protein
Quercetin inhibits the reaction [cyanoginosin LR results in increased activity of CAT protein]
CTD PMID:17383702, PMID:17654400, PMID:17696131, PMID:30940545 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression ISO cyanoginosin LR results in increased expression of CBR1 mRNA CTD PMID:17654400 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO cyanoginosin LR results in increased expression of CBR3 mRNA CTD PMID:17654400 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccdc180 coiled-coil domain containing 180 decreases expression ISO cyanoginosin LR results in decreased expression of CCDC180 mRNA CTD PMID:29518473 NCBI chr 5:61,467,799...61,542,675
Ensembl chr 5:61,474,000...61,542,653
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
ISO cyanoginosin LR results in increased expression of CCND1 mRNA
cyanoginosin LR results in decreased expression of CCND1 mRNA; cyanoginosin LR results in decreased expression of CCND1 protein
CTD PMID:17654400, PMID:28414124 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnf cyclin F decreases expression ISO cyanoginosin LR results in decreased expression of CCNF mRNA CTD PMID:17654400 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccng1 cyclin G1 increases expression ISO cyanoginosin LR results in increased expression of CCNG1 mRNA CTD PMID:17654400 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd2ap CD2-associated protein increases expression ISO cyanoginosin LR results in increased expression of CD2AP mRNA CTD PMID:17654400 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Cdc42 cell division cycle 42 increases expression ISO cyanoginosin LR results in increased expression of CDC42 mRNA CTD PMID:17654400 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions
ISO cyanoginosin LR results in decreased expression of CDH1 mRNA; cyanoginosin LR results in decreased expression of CDH1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in decreased expression of CDH1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in decreased expression of CDH1 protein]
CTD PMID:27856280 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of CDK1 protein CTD PMID:26506538 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO cyanoginosin LR results in decreased expression of CDK4 mRNA; cyanoginosin LR results in decreased expression of CDK4 protein CTD PMID:28414124 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO cyanoginosin LR results in decreased expression of CDK6 mRNA; cyanoginosin LR results in decreased expression of CDK6 protein CTD PMID:28414124 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
cyanoginosin LR results in increased expression of CDKN1A protein
pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of CDKN1A protein]
cyanoginosin LR results in increased expression of CDKN1A mRNA
CTD PMID:17654400, PMID:20421190, PMID:31157505 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO cyanoginosin LR results in decreased expression of CEBPD mRNA CTD PMID:17383702 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Coro1c coronin 1C increases expression ISO cyanoginosin LR results in increased expression of CORO1C mRNA CTD PMID:17654400 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO cyanoginosin LR results in increased expression of CREB3 mRNA CTD PMID:17654400 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases expression
ISO cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]
cyanoginosin LR results in decreased expression of CSF2 mRNA; cyanoginosin LR results in decreased expression of CSF2 protein
CTD PMID:15712326, PMID:23454832 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression ISO cyanoginosin LR results in increased expression of CSPG4 mRNA CTD PMID:29518473 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Cstb cystatin B increases expression ISO cyanoginosin LR results in increased expression of CSTB mRNA CTD PMID:17654400 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctnnb1 catenin beta 1 increases ubiquitination ISO cyanoginosin LR results in increased ubiquitination of CTNNB1 protein CTD PMID:20421190 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsl cathepsin L increases expression ISO cyanoginosin LR results in increased expression of CTSL mRNA CTD PMID:17654400 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Ctsz cathepsin Z increases expression ISO cyanoginosin LR results in increased expression of CTSZ mRNA CTD PMID:17654400 NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877
JBrowse link
G Cttn cortactin increases expression ISO cyanoginosin LR results in increased expression of CTTN mRNA CTD PMID:17654400 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO cyanoginosin LR results in increased expression of CYBB mRNA CTD PMID:17654400 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 affects expression ISO cyanoginosin LR affects the expression of CYP19A1 protein CTD PMID:28189720 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO cyanoginosin LR results in increased expression of CYP1A2 mRNA CTD PMID:17383702 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases expression ISO cyanoginosin LR results in decreased expression of CYP26A1 mRNA CTD PMID:17383702 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
affects expression
increases expression
ISO allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]; Thioctic Acid affects the reaction [cyanoginosin LR affects the expression of CYP2E1 protein]
cyanoginosin LR results in increased expression of CYP2E1 mRNA; cyanoginosin LR results in increased expression of CYP2E1 protein
CTD PMID:21684301, PMID:32061150 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO cyanoginosin LR results in decreased expression of CYP8B1 mRNA CTD PMID:17383702 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dap3 death associated protein 3 increases expression ISO cyanoginosin LR results in increased expression of DAP3 mRNA CTD PMID:17654400 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects expression
ISO cyanoginosin LR results in increased expression of DDIT3 mRNA
cyanoginosin LR affects the expression of DDIT3 protein
CTD PMID:17654400, PMID:18214937 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO cyanoginosin LR results in increased expression of DDIT4 mRNA CTD PMID:17654400 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO cyanoginosin LR results in increased expression of DDIT4L mRNA CTD PMID:17654400 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 decreases expression ISO cyanoginosin LR results in decreased expression of DECR2 mRNA; cyanoginosin LR results in decreased expression of DECR2 protein CTD PMID:17383702, PMID:26984711 NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO cyanoginosin LR results in increased expression of DGAT1 protein CTD PMID:26984711 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression ISO cyanoginosin LR results in increased expression of DIO2 protein CTD PMID:25497113 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha increases expression ISO cyanoginosin LR results in increased expression of DNMT3A mRNA CTD PMID:29518473 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta increases expression ISO cyanoginosin LR results in increased expression of DNMT3B mRNA CTD PMID:29518473 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO cyanoginosin LR results in increased expression of DUSP10 mRNA CTD PMID:17654400 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta increases expression ISO cyanoginosin LR results in increased expression of EEF1D protein CTD PMID:26984711 NCBI chr 7:116,928,264...116,942,981
Ensembl chr 7:116,928,265...116,936,674
JBrowse link
G Egfr epidermal growth factor receptor increases expression
decreases methylation
ISO cyanoginosin LR results in increased expression of EGFR mRNA
cyanoginosin LR results in decreased methylation of EGFR gene
CTD PMID:29518473 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression ISO cyanoginosin LR results in increased expression of EGR1 mRNA CTD PMID:17383702 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 affects expression ISO cyanoginosin LR affects the expression of EIF4A3 protein CTD PMID:26984711 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of EIF4EBP1 protein CTD PMID:26506538 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Epo erythropoietin decreases expression ISO cyanoginosin LR results in decreased expression of EPO mRNA; cyanoginosin LR results in decreased expression of EPO protein CTD PMID:23454832 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Esr1 estrogen receptor 1 increases expression
affects expression
ISO cyanoginosin LR results in increased expression of ESR1 protein
cyanoginosin LR affects the expression of ESR1 mRNA
CTD PMID:28189720 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv5 ETS variant transcription factor 5 decreases expression ISO cyanoginosin LR results in decreased expression of ETV5 mRNA CTD PMID:29518473 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Ezr ezrin increases expression
increases phosphorylation
multiple interactions
EXP
ISO
cyanoginosin LR results in increased expression of EZR mRNA
cyanoginosin LR results in increased phosphorylation of EZR protein
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of EZR protein modified form; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EZR protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EZR protein]
CTD PMID:23342045, PMID:24677693, PMID:27352821, PMID:27393157, PMID:29984889 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO cyanoginosin LR results in decreased expression of FABP1 protein CTD PMID:26984711 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression ISO cyanoginosin LR results in increased expression of FABP2 protein CTD PMID:26984711 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO cyanoginosin LR results in decreased expression of FADS1 protein CTD PMID:26984711 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO cyanoginosin LR results in decreased expression of FADS2 protein CTD PMID:26984711 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fasn fatty acid synthase increases expression
decreases expression
ISO cyanoginosin LR results in increased expression of FASN mRNA
cyanoginosin LR results in decreased expression of FASN protein
CTD PMID:25497113, PMID:26984711 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fgf13 fibroblast growth factor 13 decreases expression ISO cyanoginosin LR results in decreased expression of FGF13 mRNA CTD PMID:29518473 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO cyanoginosin LR results in increased expression of FGF21 mRNA CTD PMID:25497113 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fhdc1 FH2 domain containing 1 increases methylation
decreases expression
ISO cyanoginosin LR results in increased methylation of FHDC1 gene
cyanoginosin LR results in decreased expression of FHDC1 mRNA
CTD PMID:29518473 NCBI chr 2:183,450,608...183,487,820
Ensembl chr 2:183,450,619...183,487,820
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO cyanoginosin LR results in decreased expression of FN1 mRNA CTD PMID:17383702 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO cyanoginosin LR results in increased expression of FOS mRNA
cyanoginosin LR results in increased expression of FOS mRNA; cyanoginosin LR results in increased expression of FOS protein
CTD PMID:23891578, PMID:28062358 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO cyanoginosin LR results in decreased expression of FTL1 mRNA CTD PMID:17383702 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit decreases expression ISO cyanoginosin LR results in decreased expression of G6PC mRNA CTD PMID:17654400, PMID:25497113 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO cyanoginosin LR results in increased expression of GADD45A mRNA CTD PMID:17654400 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression ISO cyanoginosin LR results in decreased expression of GADD45G mRNA CTD PMID:17383702 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO cyanoginosin LR results in decreased expression of GAS1 mRNA CTD PMID:17654400 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gbp5 guanylate binding protein 5 increases expression ISO cyanoginosin LR results in increased expression of GBP5 mRNA CTD PMID:29518473 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Gck glucokinase increases expression ISO cyanoginosin LR results in increased expression of GCK mRNA CTD PMID:17654400, PMID:25497113 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
decreases expression
ISO cyanoginosin LR results in increased expression of GCLC mRNA
cyanoginosin LR results in decreased expression of and results in increased phosphorylation of GCLC protein; GCLC protein inhibits the reaction [cyanoginosin LR results in decreased activity of CAT protein]
cyanoginosin LR results in decreased expression of GCLC mRNA
CTD PMID:17654400, PMID:30940545 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO cyanoginosin LR results in increased expression of GGT1 mRNA CTD PMID:17654400 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 increases expression ISO cyanoginosin LR results in increased expression of GIPC2 mRNA CTD PMID:17654400 NCBI chr 2:257,293,161...257,377,982
Ensembl chr 2:257,293,167...257,376,756
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO cyanoginosin LR results in increased expression of GLRX3 mRNA CTD PMID:17654400 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gna13 G protein subunit alpha 13 increases expression ISO cyanoginosin LR results in increased expression of GNA13 mRNA CTD PMID:17654400 NCBI chr10:97,647,196...97,680,030
Ensembl chr10:97,647,111...97,684,730
JBrowse link
G Gnb1 G protein subunit beta 1 increases expression ISO cyanoginosin LR results in increased expression of GNB1 mRNA CTD PMID:17654400 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO cyanoginosin LR results in increased expression of GPAM protein CTD PMID:26984711 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO cyanoginosin LR results in decreased expression of GPX1 protein CTD PMID:30076769 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO cyanoginosin LR results in increased expression of GPX2 mRNA CTD PMID:17654400 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO cyanoginosin LR results in increased expression of GPX3 mRNA CTD PMID:17654400 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO cyanoginosin LR results in increased expression of GPX4 mRNA CTD PMID:17654400 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions
increases phosphorylation
ISO cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3A protein]; cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein]
cyanoginosin LR results in increased phosphorylation of GSK3A protein
CTD PMID:28984034, PMID:31714646, PMID:32073747 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased phosphorylation of GSK3B protein
cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein
cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3B protein]; cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein]
CTD PMID:20421190, PMID:28984034, PMID:32073747 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin increases expression ISO cyanoginosin LR results in increased expression of GSN mRNA CTD PMID:17654400 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
decreases activity
multiple interactions
increases activity
ISO
EXP
cyanoginosin LR results in increased expression of GSR mRNA
cyanoginosin LR results in decreased activity of GSR protein
Thioctic Acid inhibits the reaction [cyanoginosin LR results in decreased activity of GSR protein]
[cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased activity of GSR protein
cyanoginosin LR results in increased activity of GSR protein
CTD PMID:17654400, PMID:25410294, PMID:32061150 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression ISO cyanoginosin LR results in increased expression of GSS mRNA CTD PMID:17654400 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO GSTA1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR CTD PMID:21504230 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO cyanoginosin LR results in increased expression of GSTA2 mRNA CTD PMID:17654400 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression ISO cyanoginosin LR results in decreased expression of GSTA3 mRNA CTD PMID:17654400 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO cyanoginosin LR results in increased expression of GSTA2 mRNA CTD PMID:17654400 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO cyanoginosin LR results in decreased expression of GSTK1 mRNA CTD PMID:17654400 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression
decreases expression
ISO GSTM1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR
cyanoginosin LR results in increased expression of GSTM1 mRNA; cyanoginosin LR results in increased expression of GSTM5 mRNA
cyanoginosin LR results in decreased expression of GSTM1 mRNA
CTD PMID:17383702, PMID:17654400, PMID:21504230 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO cyanoginosin LR results in increased expression of GSTM2 mRNA CTD PMID:17654400 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO cyanoginosin LR results in increased expression of GSTM4 mRNA CTD PMID:17654400 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO cyanoginosin LR results in increased expression of GSTM3 mRNA CTD PMID:17654400 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO GSTP1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR CTD PMID:21504230 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO GSTT1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR CTD PMID:21504230 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtpbp4 GTP binding protein 4 decreases expression ISO cyanoginosin LR results in decreased expression of GTPBP4 protein CTD PMID:26984711 NCBI chr17:63,111,086...63,145,618
Ensembl chr17:63,110,254...63,145,577
JBrowse link
G Gys1 glycogen synthase 1 multiple interactions ISO cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in decreased activity of GYS1 protein
cyanoginosin LR inhibits the reaction [INS protein results in decreased phosphorylation of and results in increased activity of GYS1 protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in decreased activity of GYS1 protein
CTD PMID:28984034 NCBI chr 1:101,427,195...101,447,092
Ensembl chr 1:101,427,195...101,447,092
JBrowse link
G H2bc1 H2B clustered histone 1 decreases expression EXP cyanoginosin LR results in decreased expression of H2BC1 mRNA CTD PMID:24025782 NCBI chr17:43,423,111...43,423,580
Ensembl chr17:43,423,111...43,423,580
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO cyanoginosin LR results in decreased expression of HADH protein CTD PMID:26984711 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression ISO cyanoginosin LR results in decreased expression of HADHB protein CTD PMID:26984711 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hephl1 hephaestin-like 1 decreases expression ISO cyanoginosin LR results in decreased expression of HEPHL1 mRNA CTD PMID:29518473 NCBI chr 8:13,614,800...13,680,870
Ensembl chr 8:13,614,800...13,680,870
JBrowse link
G Hk2 hexokinase 2 increases expression ISO cyanoginosin LR results in increased expression of HK2 mRNA CTD PMID:17654400, PMID:25497113 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO cyanoginosin LR results in increased expression of HMGCR mRNA CTD PMID:25497113 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO [cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; cyanoginosin LR promotes the reaction [sulforafan results in increased expression of HMOX1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of HMOX1 protein]
cyanoginosin LR results in increased expression of HMOX1 mRNA; cyanoginosin LR results in increased expression of HMOX1 protein
CTD PMID:20600217, PMID:20722399 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO cyanoginosin LR results in decreased expression of HNF4A mRNA CTD PMID:25497113 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hpx hemopexin increases expression ISO cyanoginosin LR results in increased expression of HPX protein CTD PMID:26984711 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO cyanoginosin LR results in increased expression of HSPA8 mRNA CTD PMID:17654400 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression
increases phosphorylation
multiple interactions
ISO
EXP
cyanoginosin LR results in increased expression of HSPB1 mRNA
cyanoginosin LR results in increased phosphorylation of HSPB1 protein
SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of HSPB1 protein]
CTD PMID:17654400, PMID:22000993, PMID:27393157 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression ISO cyanoginosin LR results in decreased expression of IDH1 mRNA CTD PMID:17383702 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ifng interferon gamma multiple interactions ISO cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA] CTD PMID:15712326 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igbp1 immunoglobulin binding protein 1 multiple interactions
increases response to substance
affects response to substance
ISO [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of PPP2CA protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of VASP protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of EZR protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of PPP2CA protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK1 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK3 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK9 protein; cyanoginosin LR inhibits the reaction [IGBP1 protein binds to PPP2CA protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to IGBP1 protein]
IGBP1 protein affects the susceptibility to cyanoginosin LR
CTD PMID:26784437, PMID:27393157, PMID:29984889 NCBI chr  X:70,322,764...70,345,005
Ensembl chr  X:70,322,755...70,345,005
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO cyanoginosin LR results in increased expression of IGFBP1 mRNA CTD PMID:17654400 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igkc immunoglobulin kappa constant increases expression ISO cyanoginosin LR results in increased expression of IGKC protein CTD PMID:26984711
G Il10 interleukin 10 decreases expression ISO cyanoginosin LR results in decreased expression of IL10 protein CTD PMID:26984711 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
cyanoginosin LR results in increased expression of IL1B protein
CTD PMID:15712326, PMID:26984711 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases expression ISO cyanoginosin LR results in decreased expression of IL2 protein CTD PMID:15369846 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 decreases expression ISO cyanoginosin LR results in decreased expression of IL3 mRNA; cyanoginosin LR results in decreased expression of IL3 protein CTD PMID:23454832 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO cyanoginosin LR results in increased expression of IL6 protein
cyanoginosin LR promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL6 protein]; cyanoginosin LR results in increased expression of and results in increased secretion of IL6 protein
CTD PMID:15369846, PMID:23970801, PMID:26984711, PMID:28189720 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO cyanoginosin LR results in decreased expression of INMT protein CTD PMID:26984711 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Ins2 insulin 2 multiple interactions ISO cyanoginosin LR inhibits the reaction [INS protein results in decreased phosphorylation of and results in increased activity of GYS1 protein]; cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3A protein]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3B protein]; cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]; INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3A protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]] CTD PMID:28984034 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO cyanoginosin LR results in increased expression of INSIG1 mRNA CTD PMID:17383702 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Ints2 integrator complex subunit 2 increases expression ISO cyanoginosin LR results in increased expression of INTS2 mRNA CTD PMID:29518473 NCBI chr10:73,632,805...73,690,952
Ensembl chr10:73,634,255...73,690,887
JBrowse link
G Irs1 insulin receptor substrate 1 increases phosphorylation
decreases expression
decreases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased phosphorylation of IRS1 protein
cyanoginosin LR results in decreased expression of IRS1 mRNA
cyanoginosin LR results in decreased phosphorylation of IRS1 protein
cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]; INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased phosphorylation of IRS1 protein]]
cyanoginosin LR results in decreased expression of and results in increased phosphorylation of IRS1 protein
CTD PMID:28984034, PMID:29777831, PMID:31714646, PMID:32073747 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 decreases expression
decreases phosphorylation
ISO cyanoginosin LR results in decreased expression of IRS2 mRNA; cyanoginosin LR results in decreased expression of IRS2 protein
cyanoginosin LR results in decreased phosphorylation of IRS2 protein
CTD PMID:29777831 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO cyanoginosin LR results in increased expression of JAK1 mRNA CTD PMID:17654400 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
increases phosphorylation
ISO cyanoginosin LR results in increased expression of JUN mRNA
cyanoginosin LR results in increased expression of JUN mRNA; cyanoginosin LR results in increased expression of JUN protein
cyanoginosin LR results in increased phosphorylation of JUN protein
CTD PMID:17654400, PMID:23891578, PMID:26506538, PMID:28062358 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO cyanoginosin LR results in increased expression of JUND mRNA CTD PMID:17654400 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects binding ISO cyanoginosin LR binds to KEAP1 protein CTD PMID:20722399 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif5b kinesin family member 5B decreases expression ISO cyanoginosin LR results in decreased expression of KIF5B protein CTD PMID:26984711 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression EXP cyanoginosin LR results in increased expression of KIT CTD PMID:24025782 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kpna4 karyopherin subunit alpha 4 affects expression ISO cyanoginosin LR affects the expression of KPNA4 protein CTD PMID:26984711 NCBI chr 2:165,684,345...165,739,874
Ensembl chr 2:165,684,345...165,739,874
JBrowse link
G Krt18 keratin 18 increases expression
increases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased expression of KRT18 mRNA
cyanoginosin LR results in increased phosphorylation of KRT18 protein
SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT18 protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT18 protein]
CTD PMID:17654400, PMID:22960429 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt8 keratin 8 multiple interactions
increases expression
ISO cyanoginosin LR results in increased phosphorylation of and affects the expression of KRT8 protein; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of KRT8 protein]
cyanoginosin LR results in increased expression of KRT8 mRNA
CTD PMID:17654400, PMID:22960429 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO cyanoginosin LR results in increased expression of LDLR mRNA CTD PMID:25497113 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals1 galectin 1 increases expression ISO cyanoginosin LR results in increased expression of LGALS1 mRNA CTD PMID:17654400 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals3 galectin 3 increases expression ISO cyanoginosin LR results in increased expression of LGALS3 mRNA CTD PMID:17654400 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals3bp galectin 3 binding protein increases expression ISO cyanoginosin LR results in increased expression of LGALS3BP mRNA CTD PMID:17654400 NCBI chr10:107,415,334...107,424,672
Ensembl chr10:107,415,326...107,424,710
JBrowse link
G Lpin2 lipin 2 decreases expression ISO cyanoginosin LR results in decreased expression of LPIN2 mRNA CTD PMID:17383702 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Lrp1 LDL receptor related protein 1 affects expression ISO cyanoginosin LR affects the expression of LRP1 protein CTD PMID:26984711 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Lypla2 lysophospholipase 2 decreases expression ISO cyanoginosin LR results in decreased expression of LYPLA2 protein CTD PMID:26984711 NCBI chr 5:154,315,033...154,319,629
Ensembl chr 5:154,315,033...154,319,629
JBrowse link
G Maged1 MAGE family member D1 decreases expression ISO cyanoginosin LR results in decreased expression of MAGED1 mRNA CTD PMID:29518473 NCBI chr  X:63,803,194...63,809,715
Ensembl chr  X:63,803,189...63,809,861
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO cyanoginosin LR results in increased expression of MAP3K1 mRNA CTD PMID:17654400 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPK1 protein]; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK1 protein; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:20934494, PMID:21983652, PMID:22960429, PMID:23970801, PMID:27393157, PMID:29984889 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO cyanoginosin LR results in increased expression of MAPK11 mRNA; cyanoginosin LR results in increased expression of MAPK11 protein CTD PMID:25986756 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation
EXP cyanoginosin LR results in increased phosphorylation of and results in increased activity of MAPK14 protein
cyanoginosin LR results in increased phosphorylation of MAPK14 protein
CTD PMID:22000993 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
increases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased expression of MAPK3 mRNA
cyanoginosin LR results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPK3 protein]; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK3 protein; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:17654400, PMID:20934494, PMID:21983652, PMID:22960429, PMID:23970801, PMID:27352821, PMID:27393157, PMID:29984889 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein CTD PMID:29984889 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression
multiple interactions
ISO cyanoginosin LR results in increased expression of MAPK9 mRNA
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK9 protein
CTD PMID:17654400, PMID:29984889 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau affects phosphorylation
increases phosphorylation
multiple interactions
increases localization
ISO
EXP
cyanoginosin LR affects the phosphorylation of MAPT protein
cyanoginosin LR results in increased phosphorylation of MAPT protein
SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]
Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]; Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased localization of MAPT protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]
CTD PMID:21934130, PMID:22000993, PMID:23929704, PMID:24142891, PMID:27393157 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase decreases expression ISO cyanoginosin LR results in decreased expression of MCAT protein CTD PMID:26984711 NCBI chr 7:124,412,762...124,424,966
Ensembl chr 7:124,412,762...124,423,832
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO
EXP
cyanoginosin LR results in decreased expression of MDM2 mRNA; cyanoginosin LR results in decreased expression of MDM2 protein CTD PMID:28414124, PMID:31157505 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO cyanoginosin LR results in increased expression of MET mRNA; cyanoginosin LR results in increased expression of MET protein CTD PMID:28062358 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression ISO cyanoginosin LR results in increased expression of MFGE8 mRNA CTD PMID:17654400 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mir100 microRNA 100 decreases expression ISO cyanoginosin LR results in decreased expression of MIR100 mRNA CTD PMID:29518473 NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
JBrowse link
G Mir137 microRNA 137 increases expression ISO cyanoginosin LR results in increased expression of MIR137 mRNA CTD PMID:29518473 NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
JBrowse link
G Mir181a2 microRNA 181a-2 decreases expression ISO cyanoginosin LR results in decreased expression of MIR181A-2 mRNA CTD PMID:25986756 NCBI chr 3:23,150,352...23,150,468
Ensembl chr 3:23,150,352...23,150,468
JBrowse link
G Mir19a microRNA 19a decreases expression ISO cyanoginosin LR results in decreased expression of MIR19A mRNA CTD PMID:29518473 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir204 microRNA 204 decreases expression ISO cyanoginosin LR results in decreased expression of MIR204 mRNA CTD PMID:29518473 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir27a microRNA 27a increases expression ISO cyanoginosin LR results in increased expression of MIR27A mRNA CTD PMID:29518473 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir30b microRNA 30b increases expression ISO cyanoginosin LR results in increased expression of MIR30B mRNA CTD PMID:29518473 NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
JBrowse link
G Mir31 microRNA 31 decreases expression ISO cyanoginosin LR results in decreased expression of MIR31 mRNA CTD PMID:29518473 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir320a microRNA 320a decreases expression ISO cyanoginosin LR results in decreased expression of MIR320A mRNA CTD PMID:29518473 NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
JBrowse link
G Mir33 microRNA 33 increases expression ISO cyanoginosin LR results in increased expression of MIR33A mRNA CTD PMID:29518473 NCBI chr 7:123,431,612...123,431,680
Ensembl chr 7:123,431,612...123,431,680
JBrowse link
G Mir331 microRNA 331 increases expression ISO cyanoginosin LR results in increased expression of MIR331 mRNA CTD PMID:29518473 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir342 microRNA 342 decreases expression ISO cyanoginosin LR results in decreased expression of MIR342 mRNA CTD PMID:29518473 NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO cyanoginosin LR results in increased expression of MKI67 protein CTD PMID:28189720 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmgt1 membrane magnesium transporter 1 decreases expression ISO cyanoginosin LR results in decreased expression of MMGT1 protein CTD PMID:26984711 NCBI chr  X:158,966,694...158,978,995
Ensembl chr  X:158,966,673...158,978,995
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression ISO cyanoginosin LR results in increased expression of MMP13 mRNA CTD PMID:29518473 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO cyanoginosin LR results in increased expression of MMP2 mRNA; cyanoginosin LR results in increased expression of MMP2 protein CTD PMID:20934494 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
decreases expression
ISO cyanoginosin LR results in increased expression of MMP9 mRNA; cyanoginosin LR results in increased expression of MMP9 protein
cyanoginosin LR results in decreased expression of MMP9 protein
CTD PMID:20934494, PMID:28189720 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 decreases expression ISO cyanoginosin LR results in decreased expression of MRPS7 protein CTD PMID:26984711 NCBI chr10:104,155,805...104,158,840
Ensembl chr10:104,155,805...104,158,839
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 decreases expression ISO cyanoginosin LR results in decreased expression of MS4A7 mRNA CTD PMID:29518473 NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
JBrowse link
G Msn moesin increases expression EXP cyanoginosin LR results in increased expression of MSN mRNA CTD PMID:23342045 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Msrb1 methionine sulfoxide reductase B1 decreases expression ISO cyanoginosin LR results in decreased expression of MSRB1 mRNA CTD PMID:17654400 NCBI chr10:14,105,750...14,111,463
Ensembl chr10:14,105,750...14,111,463
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 increases expression EXP cyanoginosin LR results in increased expression of ATP6 mRNA CTD PMID:23342045 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 increases expression EXP cyanoginosin LR results in increased expression of ATP8 mRNA CTD PMID:23342045 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression EXP cyanoginosin LR results in increased expression of COX1 mRNA CTD PMID:23342045 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II increases expression EXP cyanoginosin LR results in increased expression of COX2 mRNA CTD PMID:23342045 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases expression EXP cyanoginosin LR results in increased expression of COX3 mRNA CTD PMID:23342045 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression EXP cyanoginosin LR results in increased expression of ND1 mRNA CTD PMID:23342045 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 increases expression EXP cyanoginosin LR results in increased expression of ND3 mRNA CTD PMID:23342045 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 increases expression EXP cyanoginosin LR results in increased expression of ND6 mRNA CTD PMID:23342045 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt1 metallothionein 1 decreases expression
increases expression
ISO cyanoginosin LR results in decreased expression of MT1 mRNA
cyanoginosin LR results in increased expression of MT1 mRNA
CTD PMID:17383702, PMID:17654400 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression ISO cyanoginosin LR results in increased expression of MT2 mRNA CTD PMID:17654400 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression ISO cyanoginosin LR results in increased expression of MTOR protein CTD PMID:25497113 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mttp microsomal triglyceride transfer protein affects expression ISO cyanoginosin LR affects the expression of MTTP protein CTD PMID:26984711 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
increases phosphorylation
ISO cyanoginosin LR results in increased expression of MYC mRNA
cyanoginosin LR results in increased phosphorylation of MYC protein
cyanoginosin LR results in increased expression of MYC mRNA; cyanoginosin LR results in increased expression of MYC protein
CTD PMID:17654400, PMID:20421190, PMID:23891578, PMID:24607848, PMID:26506538, PMID:28062358 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression
decreases methylation
ISO cyanoginosin LR results in increased expression of MYLK3 mRNA
cyanoginosin LR results in decreased methylation of MYLK3 gene
CTD PMID:29518473 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 increases expression ISO cyanoginosin LR results in increased expression of NAIP2 mRNA CTD PMID:17654400 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Nalcn sodium leak channel, non-selective increases methylation
decreases expression
ISO cyanoginosin LR results in increased methylation of NALCN gene
cyanoginosin LR results in decreased expression of NALCN mRNA
CTD PMID:29518473 NCBI chr15:109,734,092...110,046,729
Ensembl chr15:109,735,595...110,046,704
JBrowse link
G Necap1 NECAP endocytosis associated 1 decreases expression ISO cyanoginosin LR results in decreased expression of NECAP1 protein CTD PMID:26984711 NCBI chr 4:155,709,712...155,724,801
Ensembl chr 4:155,709,613...155,724,790
JBrowse link
G Net1 neuroepithelial cell transforming 1 increases expression ISO cyanoginosin LR results in increased expression of NET1 mRNA CTD PMID:17654400 NCBI chr17:69,991,786...70,020,977
Ensembl chr17:70,010,794...70,020,982
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects expression
affects response to substance
decreases degradation
ISO [cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; cyanoginosin LR inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; cyanoginosin LR promotes the reaction [sulforafan affects the localization of NFE2L2 protein]; cyanoginosin LR results in increased expression of and results in increased activity of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of HMOX1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of NQO1 protein]
[Thioctic Acid co-treated with cyanoginosin LR] results in increased expression of NFE2L2 protein
cyanoginosin LR affects the expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to cyanoginosin LR
cyanoginosin LR results in decreased degradation of NFE2L2 protein
CTD PMID:20600217, PMID:20722399, PMID:32061150 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation
ISO cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]
cyanoginosin LR results in increased phosphorylation of NFKBIA protein
CTD PMID:23970801 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:15712326 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression ISO cyanoginosin LR results in decreased expression of NOX4 mRNA CTD PMID:17654400 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO cyanoginosin LR results in increased expression of NQO1 mRNA
cyanoginosin LR results in increased expression of NQO1 mRNA; cyanoginosin LR results in increased expression of NQO1 protein
[cyanoginosin LR affects the localization of and results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; cyanoginosin LR promotes the reaction [sulforafan results in increased expression of NQO1 protein]; NFE2L2 protein affects the susceptibility to [cyanoginosin LR results in increased expression of NQO1 protein]
CTD PMID:17654400, PMID:20600217, PMID:20722399 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nras NRAS proto-oncogene, GTPase increases expression ISO cyanoginosin LR results in increased expression of NRAS mRNA
cyanoginosin LR results in increased expression of NRAS mRNA; cyanoginosin LR results in increased expression of NRAS protein
CTD PMID:17654400, PMID:28062358 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO cyanoginosin LR results in increased expression of NUPR1 mRNA CTD PMID:17654400 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Ocln occludin decreases expression ISO
EXP
cyanoginosin LR results in decreased expression of OCLN protein CTD PMID:25986756, PMID:27758031 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO cyanoginosin LR results in increased expression of PAK1 mRNA CTD PMID:17654400 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO
EXP
cyanoginosin LR results in increased cleavage of PARP1 protein
pifithrin inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein]
sulforafan inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein]
CTD PMID:21684301, PMID:31157505 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcyt2 phosphate cytidylyltransferase 2, ethanolamine decreases expression ISO cyanoginosin LR results in decreased expression of PCYT2 protein CTD PMID:26984711 NCBI chr10:109,788,348...109,795,743
Ensembl chr10:109,788,350...109,795,697
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha increases expression ISO cyanoginosin LR results in increased expression of PDGFRA mRNA CTD PMID:17654400 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO cyanoginosin LR results in decreased expression of PDIA4 mRNA CTD PMID:17383702 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of PDPK1 protein CTD PMID:20421190 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Pdzk1 PDZ domain containing 1 decreases expression ISO cyanoginosin LR results in decreased expression of PDZK1 protein CTD PMID:26984711 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Pepd peptidase D decreases expression ISO cyanoginosin LR results in decreased expression of PEPD protein CTD PMID:26984711 NCBI chr 1:90,820,670...91,285,128 JBrowse link
G Pfn1 profilin 1 decreases expression ISO cyanoginosin LR results in decreased expression of PFN1 mRNA CTD PMID:17383702 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Pfn2 profilin 2 increases expression ISO cyanoginosin LR results in increased expression of PFN2 mRNA CTD PMID:17654400 NCBI chr 2:147,953,858...147,959,692
Ensembl chr 2:147,955,196...148,050,438
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO cyanoginosin LR results in increased expression of PGD mRNA CTD PMID:17654400 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pigr polymeric immunoglobulin receptor decreases expression ISO cyanoginosin LR results in decreased expression of PIGR mRNA CTD PMID:17383702 NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO cyanoginosin LR results in decreased expression of PIK3R3 mRNA; cyanoginosin LR results in decreased expression of PIK3R3 protein CTD PMID:28414124 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Pitrm1 pitrilysin metallopeptidase 1 decreases expression ISO cyanoginosin LR results in decreased expression of PITRM1 protein CTD PMID:26984711 NCBI chr17:68,477,423...68,509,113
Ensembl chr17:68,477,446...68,509,120
JBrowse link
G Plin3 perilipin 3 increases expression ISO cyanoginosin LR results in increased expression of PLIN3 protein CTD PMID:26984711 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Plk1 polo-like kinase 1 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of PLK1 protein CTD PMID:26506538 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO cyanoginosin LR results in increased expression of PLK3 mRNA CTD PMID:17654400 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta increases expression ISO cyanoginosin LR results in increased expression of PMPCB protein CTD PMID:26984711 NCBI chr 4:9,908,838...9,921,615
Ensembl chr 4:9,908,831...9,921,610
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha affects binding
multiple interactions
EXP
ISO
cyanoginosin LR binds to PPP2CA protein
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of PPP2CA protein modified form; [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased expression of PPP2CA protein; cyanoginosin LR inhibits the reaction [IGBP1 protein binds to PPP2CA protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to IGBP1 protein]; cyanoginosin LR inhibits the reaction [PPP2CA protein binds to PPP2R1A protein]; cyanoginosin LR inhibits the reaction [PPP2R1A protein binds to PPP2CA protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of and results in increased methylation of PPP2CA protein
cyanoginosin LR results in increased phosphorylation of and results in decreased activity of PPP2CA protein
CTD PMID:22000993, PMID:27393157, PMID:29984889 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression
decreases expression
multiple interactions
EXP
ISO
cyanoginosin LR results in increased expression of PPP2R1A protein
cyanoginosin LR results in decreased expression of PPP2R1A protein
cyanoginosin LR inhibits the reaction [PPP2CA protein binds to PPP2R1A protein]; cyanoginosin LR inhibits the reaction [PPP2R1A protein binds to PPP2CA protein]
CTD PMID:18214937, PMID:22000993, PMID:27393157, PMID:29984889 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha affects expression
decreases expression
multiple interactions
EXP
ISO
cyanoginosin LR affects the expression of PPP2R2A protein
cyanoginosin LR results in decreased expression of PPP2R2A protein
cyanoginosin LR results in increased expression of and affects the localization of PPP2R2A protein
CTD PMID:22000993, PMID:23436320, PMID:27393157 NCBI chr15:43,673,958...43,733,182
Ensembl chr15:43,673,960...43,733,182
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases methylation
decreases expression
ISO cyanoginosin LR results in increased methylation of PRKAR2B gene
cyanoginosin LR results in decreased expression of PRKAR2B mRNA
CTD PMID:29518473 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prkd3 protein kinase D3 increases expression ISO cyanoginosin LR results in increased expression of PRKD3 mRNA CTD PMID:17383702 NCBI chr 6:1,546,018...1,622,232
Ensembl chr 6:1,548,415...1,622,196
JBrowse link
G Prune1 prune exopolyphosphatase 1 decreases expression ISO cyanoginosin LR results in decreased expression of PRUNE1 protein CTD PMID:26984711 NCBI chr 2:196,427,714...196,457,105
Ensembl chr 2:196,427,710...196,456,481
JBrowse link
G Pten phosphatase and tensin homolog decreases expression ISO cyanoginosin LR results in decreased expression of PTEN mRNA; cyanoginosin LR results in decreased expression of PTEN protein CTD PMID:28062358 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Rad21 RAD21 cohesin complex component decreases expression ISO cyanoginosin LR results in decreased expression of RAD21 protein CTD PMID:26984711 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
JBrowse link
G Ralb RAS like proto-oncogene B increases expression ISO cyanoginosin LR results in increased expression of RALB mRNA CTD PMID:17654400 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Rbm39 RNA binding motif protein 39 increases expression ISO cyanoginosin LR results in increased expression of RBM39 protein CTD PMID:26984711 NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
JBrowse link
G Rdx radixin decreases expression EXP cyanoginosin LR results in decreased expression of RDX mRNA CTD PMID:23342045 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity ISO cyanoginosin LR results in increased activity of RELA protein CTD PMID:30076769 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rhob ras homolog family member B increases expression ISO cyanoginosin LR results in increased expression of RHOB mRNA CTD PMID:17654400 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rhoc ras homolog family member C increases expression ISO cyanoginosin LR results in increased expression of RHOC mRNA CTD PMID:17654400 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO cyanoginosin LR results in increased expression of RHOQ mRNA CTD PMID:17654400 NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO cyanoginosin LR results in increased expression of RIT1 mRNA CTD PMID:17654400 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rps6 ribosomal protein S6 increases phosphorylation ISO cyanoginosin LR results in increased phosphorylation of RPS6 protein CTD PMID:26506538 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
increases expression
multiple interactions
EXP
ISO
cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein
cyanoginosin LR results in increased expression of RPS6KB1 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]; cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]; INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; Sirolimus inhibits the reaction [cyanoginosin LR promotes the reaction [INS protein results in increased expression of RPS6KB1 protein modified form]]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]; Sirolimus inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]; Sirolimus inhibits the reaction [INS protein promotes the reaction [cyanoginosin LR results in increased expression of RPS6KB1 protein modified form]]
naringin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:15342961, PMID:26506538, PMID:28984034, PMID:31714646 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression ISO cyanoginosin LR results in increased expression of H2-D1 protein CTD PMID:26984711 NCBI chr20:5,374,990...5,378,536
Ensembl chr20:5,374,985...5,378,539
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO cyanoginosin LR results in increased expression of S100A11 mRNA CTD PMID:17654400 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G Serpinb6a serpin family B member 6A increases expression ISO cyanoginosin LR results in increased expression of SERPINB6A mRNA CTD PMID:17654400 NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression ISO cyanoginosin LR results in increased expression of SIAH1 mRNA CTD PMID:20421190 NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO cyanoginosin LR results in decreased expression of SLC10A1 mRNA CTD PMID:17654400 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO cyanoginosin LR results in decreased expression of SLC22A7 mRNA CTD PMID:17654400 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO cyanoginosin LR results in increased expression of SLC2A2 mRNA CTD PMID:25497113 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO cyanoginosin LR results in increased expression of SLC7A11 mRNA CTD PMID:17654400 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO cyanoginosin LR results in decreased expression of SLCO1A4 mRNA CTD PMID:17654400 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1A5 increases expression EXP cyanoginosin LR results in increased expression of SLCO1A5 mRNA CTD PMID:22579952 NCBI chr 4:176,445,856...176,528,117
Ensembl chr 4:176,445,858...176,528,110
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression
increases import
multiple interactions
increases uptake
increases response to substance
affects response to substance
ISO cyanoginosin LR results in decreased expression of SLCO1B2 mRNA
SLCO1B3 protein results in increased import of cyanoginosin LR
Cyclosporine inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Dehydroepiandrosterone Sulfate inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]; Okadaic Acid inhibits the reaction [SLCO1B3 protein results in increased uptake of cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Sulfobromophthalein inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]; Taurocholic Acid inhibits the reaction [SLCO1B3 protein results in increased susceptibility to cyanoginosin LR]
SLCO1B2 protein affects the susceptibility to cyanoginosin LR
SLCO1B2 results in increased susceptibility to cyanoginosin LR
CTD PMID:17369605, PMID:17654400, PMID:18296417, PMID:19027771, PMID:20171238, PMID:25456266, PMID:26134461 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 increases expression EXP cyanoginosin LR results in increased expression of SLCO3A1 mRNA; cyanoginosin LR results in increased expression of SLCO3A1 protein CTD PMID:22579952 NCBI chr 1:135,790,854...136,073,640
Ensembl chr 1:135,790,810...136,073,540
JBrowse link
G Slco6b1 solute carrier organic anion transporter family member 6B1 increases expression EXP cyanoginosin LR results in increased expression of SLCO6B1 mRNA CTD PMID:22579952 NCBI chr 9:104,388,232...104,468,005
Ensembl chr 9:104,392,850...104,467,973
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of SMAD2 protein]; cyanoginosin LR results in increased expression of and results in increased phosphorylation of SMAD2 protein; SMAD2 protein affects the reaction [cyanoginosin LR results in decreased expression of CDH1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of SNAI1 protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of VIM protein] CTD PMID:27856280 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 increases expression ISO cyanoginosin LR results in increased expression of SMOC2 mRNA CTD PMID:17654400 NCBI chr 1:56,242,289...56,374,106
Ensembl chr 1:56,242,346...56,374,120
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression
multiple interactions
ISO cyanoginosin LR results in increased expression of SNAI1 mRNA; cyanoginosin LR results in increased expression of SNAI1 protein
SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of SNAI1 protein]
CTD PMID:27856280 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Sod1 superoxide dismutase 1 increases activity ISO cyanoginosin LR results in increased activity of SOD1 protein CTD PMID:30076769 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO cyanoginosin LR results in decreased expression of SOD2 mRNA CTD PMID:17654400 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spint2 serine peptidase inhibitor, Kunitz type, 2 increases expression ISO cyanoginosin LR results in increased expression of SPINT2 mRNA CTD PMID:17654400 NCBI chr 1:87,199,373...87,221,826
Ensembl chr 1:87,199,313...87,221,892
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO cyanoginosin LR results in decreased expression of SREBF1 mRNA CTD PMID:17654400 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO cyanoginosin LR results in increased expression of SREBF2 mRNA CTD PMID:25497113 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP cyanoginosin LR results in decreased expression of STMN1 mRNA CTD PMID:23342045 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO cyanoginosin LR results in decreased expression of SUCLG2 mRNA CTD PMID:17383702 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases expression ISO cyanoginosin LR results in increased expression of SULT1B1 protein CTD PMID:26984711 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 increases expression ISO cyanoginosin LR results in increased expression of SYNE1 mRNA CTD PMID:29518473 NCBI chr 1:41,608,287...41,763,591
NCBI chr 1:41,844,840...42,086,662
Ensembl chr 1:41,608,418...42,077,535
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO cyanoginosin LR results in increased expression of TGFB2 mRNA CTD PMID:17654400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO cyanoginosin LR results in increased expression of TGM2 mRNA CTD PMID:17654400 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thra thyroid hormone receptor alpha increases expression ISO cyanoginosin LR results in increased expression of THRA protein CTD PMID:25497113 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO cyanoginosin LR results in decreased expression of THRSP mRNA CTD PMID:17654400 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO
EXP
cyanoginosin LR results in decreased expression of TJP1 protein CTD PMID:25986756, PMID:27758031 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression ISO cyanoginosin LR results in increased expression of TMSB10 mRNA CTD PMID:17654400 NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275
JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO cyanoginosin LR results in increased expression of TMSB4X mRNA CTD PMID:17654400 NCBI chr  X:28,593,405...28,617,267
Ensembl chr  X:28,593,405...28,595,395
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
ISO cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; cyanoginosin LR promotes the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]
cyanoginosin LR results in increased expression of TNF mRNA; cyanoginosin LR results in increased expression of TNF protein
cyanoginosin LR results in decreased expression of TNF mRNA
cyanoginosin LR inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cyanoginosin LR promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL6 protein]; sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of TNF mRNA]
CTD PMID:15712326, PMID:21684301, PMID:23454832, PMID:23970801, PMID:26984711, PMID:28189720 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO cyanoginosin LR results in increased expression of TNFRSF12A mRNA CTD PMID:17654400 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnp2 transition protein 2 decreases expression EXP cyanoginosin LR results in decreased expression of TNP2 mRNA CTD PMID:24025782 NCBI chr10:4,953,898...4,954,626
Ensembl chr10:4,953,879...4,954,624
JBrowse link
G Tnpo1 transportin 1 decreases expression ISO cyanoginosin LR results in decreased expression of TNPO1 protein CTD PMID:26984711 NCBI chr 2:29,056,219...29,126,882
Ensembl chr 2:29,056,219...29,121,104
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
increases phosphorylation
ISO
EXP
cyanoginosin LR results in increased expression of TP53; cyanoginosin LR results in increased expression of TP53 mRNA; cyanoginosin LR results in increased expression of TP53 protein
[cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein; pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of TP53 protein]
cyanoginosin LR results in increased expression of TRP53 protein
cyanoginosin LR results in increased phosphorylation of TRP53 protein
cyanoginosin LR results in increased phosphorylation of TP53 protein
CTD PMID:16624733, PMID:18214937, PMID:20421190, PMID:22539157, PMID:23454832, PMID:23891578, PMID:25410294, PMID:28414124, PMID:31157505 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO cyanoginosin LR results in increased expression of TPM1 mRNA CTD PMID:17654400 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Treh trehalase increases expression ISO cyanoginosin LR results in increased expression of TREH mRNA CTD PMID:17654400 NCBI chr 8:48,983,802...48,998,072
Ensembl chr 8:48,983,802...48,997,191
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO cyanoginosin LR results in increased expression of TRIB3 mRNA CTD PMID:17383702 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trrap transformation/transcription domain-associated protein increases expression ISO cyanoginosin LR results in increased expression of TRRAP mRNA CTD PMID:29518473 NCBI chr12:11,537,950...11,627,563
Ensembl chr12:11,537,950...11,627,563
JBrowse link
G Ttn titin increases expression ISO cyanoginosin LR results in increased expression of TTN mRNA CTD PMID:29518473 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Ttr transthyretin decreases expression ISO cyanoginosin LR results in decreased expression of TTR mRNA CTD PMID:17654400 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tub TUB bipartite transcription factor affects expression
decreases acetylation
EXP cyanoginosin LR affects the expression of TUB protein modified form
cyanoginosin LR results in decreased acetylation of TUB protein
CTD PMID:22000993 NCBI chr 1:173,550,929...173,629,550
Ensembl chr 1:173,607,101...173,625,550
JBrowse link
G Txndc12 thioredoxin domain containing 12 decreases expression ISO cyanoginosin LR results in decreased expression of TXNDC12 protein CTD PMID:26984711 NCBI chr 5:128,450,830...128,475,858
Ensembl chr 5:128,450,680...128,475,864
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO cyanoginosin LR results in increased expression of TXNRD1 mRNA CTD PMID:17654400 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 decreases expression ISO cyanoginosin LR results in decreased expression of UBA2 protein CTD PMID:26984711 NCBI chr 1:90,010,681...90,035,522
Ensembl chr 1:90,011,306...90,035,522
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO cyanoginosin LR results in increased expression of UGDH mRNA CTD PMID:17654400 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 increases expression ISO cyanoginosin LR results in increased expression of UGP2 mRNA CTD PMID:17654400 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Upp2 uridine phosphorylase 2 increases expression ISO cyanoginosin LR results in increased expression of UPP2 mRNA CTD PMID:17383702 NCBI chr 3:44,806,106...44,846,464
Ensembl chr 3:44,806,106...44,846,464
JBrowse link
G Usp7 ubiquitin specific peptidase 7 decreases expression ISO cyanoginosin LR results in decreased expression of USP7 protein CTD PMID:26984711 NCBI chr10:6,930,462...7,019,910
Ensembl chr10:6,975,244...7,018,930
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation
multiple interactions
ISO cyanoginosin LR results in increased phosphorylation of VASP protein
[IGBP1 protein results in increased susceptibility to cyanoginosin LR] which affects the expression of VASP protein modified form; cyanoginosin LR results in increased phosphorylation of and affects the localization of VASP protein; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VASP protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VASP protein]
CTD PMID:23929704, PMID:24677693, PMID:27352821, PMID:27393157, PMID:29984889 NCBI chr 1:80,170,608...80,185,882
Ensembl chr 1:80,170,619...80,185,882
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression EXP cyanoginosin LR results in increased expression of VDAC1 mRNA; cyanoginosin LR results in increased expression of VDAC1 protein CTD PMID:31157505 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vim vimentin increases phosphorylation
increases expression
affects localization
multiple interactions
ISO
EXP
cyanoginosin LR results in increased phosphorylation of VIM protein
cyanoginosin LR results in increased expression of VIM mRNA
cyanoginosin LR affects the localization of VIM protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in decreased expression of VIM protein]; SB 203580 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VIM protein]; SMAD2 protein affects the reaction [cyanoginosin LR results in increased expression of VIM protein]; U 0126 inhibits the reaction [cyanoginosin LR results in increased phosphorylation of VIM protein]
CTD PMID:22960429, PMID:23342045, PMID:27393157, PMID:27856280 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO cyanoginosin LR results in increased expression of WEE1 mRNA CTD PMID:17654400 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Xylt1 xylosyltransferase 1 decreases expression ISO cyanoginosin LR results in decreased expression of XYLT1 mRNA CTD PMID:29518473 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma increases expression ISO cyanoginosin LR results in increased expression of YWHAG mRNA CTD PMID:17654400 NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta increases expression ISO cyanoginosin LR results in increased expression of YWHAH mRNA CTD PMID:17654400 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression ISO cyanoginosin LR results in increased expression of YWHAZ mRNA CTD PMID:17654400 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link
G Zfp704 zinc finger protein 704 decreases methylation
increases expression
ISO cyanoginosin LR results in decreased methylation of ZNF704 gene
cyanoginosin LR results in increased expression of ZNF704 mRNA
CTD PMID:29518473 NCBI chr 2:94,377,059...94,559,838
Ensembl chr 2:94,377,072...94,551,529
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        aetiopathogenetic role 18936
          hepatotoxic agent 14564
            microcystin 471
              microcystin LF 4
              microcystin LW 0
              microcystin RR 93
              microcystin-LR 353
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        carboacyl group 17346
                                          univalent carboacyl group 17346
                                            carbamoyl group 17132
                                              carboxamide 17132
                                                peptide 9391
                                                  cyclic peptide 8720
                                                    heterodetic cyclic peptide 1437
                                                      microcystin 471
                                                        microcystin LF 4
                                                        microcystin LW 0
                                                        microcystin RR 93
                                                        microcystin-LR 353
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.