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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:HC toxin
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Accession:CHEBI:48028 term browser browse the term
Definition:A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.
Synonyms:related_synonym: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine);   Cyclo(aoe-pro-ala-ala);   Formula=C21H32N4O6;   InChI=1S/C21H32N4O6/c1-12-18(27)22-13(2)19(28)24-14(7-4-3-5-9-16(26)17-11-31-17)21(30)25-10-6-8-15(25)20(29)23-12/h12-15,17H,3-11H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)/t12-,13+,14-,15+,17?/m0/s1;   InChIKey=GNYCTMYOHGBSBI-KVUCBBCISA-N;   SMILES=[H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)C1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O
 xref: Beilstein:4729824;   CAS:83209-65-8;   KEGG:C15676
 xref_mesh: MESH:C037654
 xref: PMID:10671527;   PMID:12297630;   PMID:15283467;   PMID:16839576;   PMID:18074352;   PMID:18230731;   PMID:18262346;   PMID:19737099;   PMID:3918884;   PMID:9917303;   Patent:EP2194061;   Reaxys:4729824


show annotations for term's descendants           Sort by:
HC toxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldc glycine decarboxylase increases expression ISO HC toxin results in increased expression of GLDC mRNA CTD PMID:33770205 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097 		JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO HC toxin results in decreased expression of GPR183 mRNA CTD PMID:33770205 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO HC toxin results in increased expression of IDI1 mRNA CTD PMID:33770205 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Klhl42 kelch-like family, member 42 decreases expression ISO HC toxin results in decreased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283 		JBrowse link
G Mepce methylphosphate capping enzyme decreases expression ISO HC toxin results in decreased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
G Nrros negative regulator of reactive oxygen species decreases expression ISO HC toxin results in decreased expression of NRROS mRNA CTD PMID:33770205 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 decreases expression ISO HC toxin results in decreased expression of PPIL1 mRNA CTD PMID:33770205 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354 		JBrowse link
G Srgap3 SLIT-ROBO Rho GTPase activating protein 3 increases expression ISO HC toxin results in increased expression of SRGAP3 mRNA CTD PMID:33770205 NCBI chr 4:145,839,369...146,070,556
Ensembl chr 4:145,840,078...146,070,575 		JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 increases expression ISO HC toxin results in increased expression of TMCC2 mRNA CTD PMID:33770205 NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa increases expression ISO HC toxin results in increased expression of TUBB2A mRNA CTD PMID:33770205 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase increases expression ISO HC toxin results in increased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        biochemical role 19501
          metabolite 19486
            HC toxin 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        carboacyl group 17687
                                          univalent carboacyl group 17687
                                            carbamoyl group 17531
                                              carboxamide 17531
                                                peptide 9564
                                                  cyclic peptide 8831
                                                    homodetic cyclic peptide 8388
                                                      HC toxin 11
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