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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:HC toxin
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Accession:CHEBI:48028 term browser browse the term
Definition:A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.
Synonyms:related_synonym: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine);   Cyclo(aoe-pro-ala-ala);   Formula=C21H32N4O6;   InChI=1S/C21H32N4O6/c1-12-18(27)22-13(2)19(28)24-14(7-4-3-5-9-16(26)17-11-31-17)21(30)25-10-6-8-15(25)20(29)23-12/h12-15,17H,3-11H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)/t12-,13+,14-,15+,17?/m0/s1;   InChIKey=GNYCTMYOHGBSBI-KVUCBBCISA-N;   SMILES=[H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)C1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O
 xref: Beilstein:4729824;   CAS:83209-65-8;   KEGG:C15676
 xref_mesh: MESH:C037654
 xref: PMID:10671527;   PMID:12297630;   PMID:15283467;   PMID:16839576;   PMID:18074352;   PMID:18230731;   PMID:18262346;   PMID:19737099;   PMID:3918884;   PMID:9917303;   Patent:EP2194061;   Reaxys:4729824



show annotations for term's descendants           Sort by:
HC toxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldc glycine decarboxylase increases expression ISO HC toxin results in increased expression of GLDC mRNA CTD PMID:33770205 NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO HC toxin results in decreased expression of GPR183 mRNA CTD PMID:33770205 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO HC toxin results in increased expression of IDI1 mRNA CTD PMID:33770205 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Klhl42 kelch-like family, member 42 decreases expression ISO HC toxin results in decreased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
JBrowse link
G Mepce methylphosphate capping enzyme decreases expression ISO HC toxin results in decreased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
JBrowse link
G Nrros negative regulator of reactive oxygen species decreases expression ISO HC toxin results in decreased expression of NRROS mRNA CTD PMID:33770205 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 decreases expression ISO HC toxin results in decreased expression of PPIL1 mRNA CTD PMID:33770205 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354
JBrowse link
G Srgap3 SLIT-ROBO Rho GTPase activating protein 3 increases expression ISO HC toxin results in increased expression of SRGAP3 mRNA CTD PMID:33770205 NCBI chr 4:145,839,369...146,070,556
Ensembl chr 4:145,840,078...146,070,575
JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 increases expression ISO HC toxin results in increased expression of TMCC2 mRNA CTD PMID:33770205 NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716
JBrowse link
G Tubb2a tubulin, beta 2A class IIa increases expression ISO HC toxin results in increased expression of TUBB2A mRNA CTD PMID:33770205 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase increases expression ISO HC toxin results in increased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19863
    role 19835
      biological role 19833
        biochemical role 19540
          metabolite 19527
            HC toxin 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19863
    subatomic particle 19861
      composite particle 19861
        hadron 19861
          baryon 19861
            nucleon 19861
              atomic nucleus 19861
                atom 19861
                  main group element atom 19807
                    p-block element atom 19807
                      carbon group element atom 19748
                        carbon atom 19744
                          organic molecular entity 19744
                            heteroorganic entity 19498
                              organochalcogen compound 19259
                                organooxygen compound 19175
                                  carbon oxoacid 18642
                                    carboxylic acid 18639
                                      carboacyl group 17708
                                        univalent carboacyl group 17708
                                          carbamoyl group 17559
                                            carboxamide 17559
                                              peptide 11128
                                                cyclic peptide 8878
                                                  homodetic cyclic peptide 8397
                                                    HC toxin 11
paths to the root