CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: N-glycosyl-1,3,5-triazine
Accession: CHEBI:48009
browse the term
Synonyms: related_synonym: N-glycosyl-1,3,5-triazines
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Acta2
actin alpha 2, smooth muscle, aorta
multiple interactions
ISO
Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
CTD
PMID:22841775
NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
decreases expression
ISO
Azacitidine results in decreased expression of ADAMTS1 mRNA
CTD
PMID:20823114
NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
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Adrb1
adrenergic receptor, beta 1
affects expression
EXP
Azacitidine affects the expression of ADRB1 mRNA
CTD
PMID:19002953
NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
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Adrb2
adrenergic receptor, beta 2
affects expression multiple interactions
EXP ISO
Azacitidine affects the expression of ADRB2 mRNA Azacitidine inhibits the reaction [Particulate Matter results in decreased expression of ADRB2 mRNA]
CTD
PMID:19002953 PMID:30986742
NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
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Afp
alpha fetoprotein
increases expression
ISO
Azacitidine results in increased expression of AFP mRNA
CTD
PMID:27590069
NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
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Aggf1
angiogenic factor with G patch and FHA domains 1
increases expression
ISO
Azacitidine results in increased expression of AGGF1 mRNA
CTD
PMID:19194470
NCBI chr13:95,487,191...95,511,865
Ensembl chr13:95,487,191...95,511,860
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Ahr
aryl-hydrocarbon receptor
increases expression multiple interactions
ISO EXP
Azacitidine results in increased expression of AHR mRNA [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]
CTD
PMID:12927368 PMID:17682057
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Ak5
adenylate kinase 5
increases expression
ISO
Azacitidine results in increased expression of AK5 mRNA
CTD
PMID:20823114
NCBI chr 3:152,168,461...152,373,992
Ensembl chr 3:152,168,452...152,373,997
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Akt1
thymoma viral proto-oncogene 1
multiple interactions
ISO
Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]
CTD
PMID:22841775
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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Alad
aminolevulinate, delta-, dehydratase
decreases expression
ISO
Azacitidine results in decreased expression of ALAD mRNA
CTD
PMID:19194470
NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
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Alb
albumin
decreases expression increases expression
ISO
Azacitidine results in decreased expression of ALB protein Azacitidine results in increased expression of ALB mRNA
CTD
PMID:27590069
NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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Aldh3a1
aldehyde dehydrogenase family 3, subfamily A1
multiple interactions
EXP
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]
CTD
PMID:17682057
NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247
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Anxa1
annexin A1
decreases expression
ISO
Azacitidine results in decreased expression of ANXA1 protein
CTD
PMID:17105402
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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App
amyloid beta precursor protein
decreases methylation multiple interactions
EXP
Azacitidine results in decreased methylation of APP promoter Azacitidine results in increased expression of and results in increased cleavage of APP protein; Betaine inhibits the reaction [Azacitidine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [Azacitidine results in increased expression of and results in increased cleavage of APP protein]
CTD
PMID:19635394
NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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Aqp5
aquaporin 5
decreases methylation multiple interactions increases expression
EXP
Azacitidine results in decreased methylation of AQP5 promoter [Azacitidine results in decreased methylation of AQP5 promoter] which results in increased expression of AQP5 mRNA; Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter] Azacitidine results in increased expression of AQP5 protein
CTD
PMID:17198683
NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710
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Aqp9
aquaporin 9
multiple interactions increases expression
ISO
[Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide; HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
CTD
PMID:25953102
NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
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Ar
androgen receptor
multiple interactions increases expression
ISO
[Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to bicalutamide; [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to Dihydrotestosterone
CTD
PMID:18324645
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Arhgap35
Rho GTPase activating protein 35
increases expression
ISO
Azacitidine results in increased expression of ARHGAP35 mRNA
CTD
PMID:20823114
NCBI chr 7:16,228,398...16,349,313
Ensembl chr 7:16,227,644...16,348,918
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Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
decreases expression
ISO
Azacitidine results in decreased expression of ARHGEF2 mRNA
CTD
PMID:20823114
NCBI chr 3:88,500,427...88,556,839
Ensembl chr 3:88,513,273...88,555,359
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Art1
ADP-ribosyltransferase 1
increases expression
ISO
Azacitidine results in increased expression of ART1 mRNA
CTD
PMID:20823114
NCBI chr 7:101,750,913...101,771,410
Ensembl chr 7:101,750,950...101,763,140
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Asb2
ankyrin repeat and SOCS box-containing 2
increases expression
ISO
Azacitidine results in increased expression of ASB2 mRNA
CTD
PMID:20823114
NCBI chr12:103,287,401...103,322,260
Ensembl chr12:103,287,401...103,322,260
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Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
decreases expression
ISO
Azacitidine results in decreased expression of ATP2B1 mRNA
CTD
PMID:20823114
NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
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Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C
increases expression
ISO
Azacitidine results in increased expression of ATP6V0C mRNA
CTD
PMID:20823114
NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676
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Aurka
aurora kinase A
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA
CTD
PMID:18720364
NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
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Bad
BCL2-associated agonist of cell death
increases expression multiple interactions
ISO
Azacitidine results in increased expression of BAD mRNA [Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA
CTD
PMID:21224363
NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
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Bak1
BCL2-antagonist/killer 1
multiple interactions increases expression
ISO
[Azacitidine co-treated with entinostat] results in increased expression of BAK1 mRNA Azacitidine results in increased expression of BAK1 mRNA
CTD
PMID:21224363
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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Bax
BCL2-associated X protein
multiple interactions increases expression
EXP
Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]
CTD
PMID:32278510
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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BC005537
cDNA sequence BC005537
increases expression
ISO
Azacitidine results in increased expression of C6ORF62 mRNA
CTD
PMID:19194470
NCBI chr13:24,985,640...24,996,882
Ensembl chr13:24,985,640...25,000,180
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Bcat1
branched chain aminotransferase 1, cytosolic
decreases expression
ISO
Azacitidine results in decreased expression of BCAT1 mRNA
CTD
PMID:20823114
NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
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Bcl2
B cell leukemia/lymphoma 2
decreases expression multiple interactions
EXP
Azacitidine results in decreased expression of BCL2 mRNA; Azacitidine results in decreased expression of BCL2 protein Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
CTD
PMID:32278510
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bcl2l1
BCL2-like 1
multiple interactions affects expression
ISO
[metacept-1 co-treated with Azacitidine] results in decreased expression of BCL2L1 [Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein
CTD
PMID:18443271 PMID:19148494
NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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Bcl2l13
BCL2 like 13
increases expression
ISO
Azacitidine results in increased expression of BCL2L13 mRNA
CTD
PMID:20823114
NCBI chr 6:120,813,167...120,869,803
Ensembl chr 6:120,813,173...120,869,803
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Bdnf
brain derived neurotrophic factor
increases expression multiple interactions decreases methylation
EXP
Azacitidine results in increased expression of BDNF mRNA Tetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]; Tetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]
CTD
PMID:18184782
NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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Bglap
bone gamma carboxyglutamate protein
decreases expression
ISO
Azacitidine results in decreased expression of BGLAP protein
CTD
PMID:18037191
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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Bicd1
BICD cargo adaptor 1
decreases expression
ISO
Azacitidine results in decreased expression of BICD1 mRNA
CTD
PMID:20823114
NCBI chr 6:149,310,322...149,464,827
Ensembl chr 6:149,310,384...149,464,827
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Bik
BCL2-interacting killer
multiple interactions increases expression
ISO
[Azacitidine co-treated with entinostat] results in increased expression of BIK mRNA Azacitidine results in increased expression of BIK mRNA
CTD
PMID:21224363
NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
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Bmp15
bone morphogenetic protein 15
increases expression
EXP
Azacitidine results in increased expression of BMP15 mRNA
CTD
PMID:23395740
NCBI chr X:6,226,108...6,232,778
Ensembl chr X:6,226,161...6,232,775
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Bnip3
BCL2/adenovirus E1B interacting protein 3
increases expression
ISO
Azacitidine results in increased expression of BNIP3 mRNA
CTD
PMID:25446377
NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
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Bok
BCL2-related ovarian killer
multiple interactions increases expression
ISO
[Azacitidine co-treated with entinostat] results in increased expression of BOK mRNA Azacitidine results in increased expression of BOK mRNA
CTD
PMID:21224363
NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486
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Bub1b
BUB1B, mitotic checkpoint serine/threonine kinase
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA
CTD
PMID:18720364
NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
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C3ar1
complement component 3a receptor 1
increases expression
ISO
Azacitidine results in increased expression of C3AR1 mRNA
CTD
PMID:19194470
NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
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Calca
calcitonin/calcitonin-related polypeptide, alpha
decreases methylation
ISO
Azacitidine results in decreased methylation of CALCA promoter
CTD
PMID:19299654
NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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Cald1
caldesmon 1
increases expression
ISO
Azacitidine results in increased expression of CALD1 mRNA
CTD
PMID:20823114
NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408
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Calhm2
calcium homeostasis modulator family member 2
multiple interactions increases expression
ISO
Cisplatin affects the reaction [Azacitidine results in increased expression of CALHM2 mRNA]
CTD
PMID:36336710
NCBI chr19:47,120,671...47,126,733
Ensembl chr19:47,093,792...47,126,733
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Casp3
caspase 3
affects expression multiple interactions increases expression increases activity
ISO EXP
Azacitidine affects the expression of CASP3 protein [metacept-1 co-treated with Azacitidine] results in increased expression of CASP3 Azacitidine results in increased expression of CASP3 mRNA 5-azacytidine co-treated with doxorubicin increases activity of CASP3 protein in lung cancer cells
CTD RGD
PMID:18443271 PMID:19148494 PMID:23395740 PMID:24356455
RGD:153344603
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp8
caspase 8
increases expression
ISO EXP
Azacitidine results in increased expression of CASP8 mRNA
CTD
PMID:18082045 PMID:23395740
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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Casp9
caspase 9
increases expression
EXP
Azacitidine results in increased expression of CASP9 mRNA
CTD
PMID:23395740
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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Ccna1
cyclin A1
multiple interactions decreases expression
ISO
Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]; Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]; Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter] Azacitidine results in decreased expression of CCNA1 mRNA
CTD
PMID:17698632
NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
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Ccna2
cyclin A2
multiple interactions decreases expression
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA Azacitidine results in decreased expression of CCNA2 mRNA
CTD
PMID:18720364 PMID:20823114
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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Ccnb1
cyclin B1
multiple interactions increases expression
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA Azacitidine results in increased expression of CCNB1 protein
CTD
PMID:18720364 PMID:20607034
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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Ccnd1
cyclin D1
increases expression
ISO
Azacitidine results in increased expression of CCND1 mRNA
CTD
PMID:20823114
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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Ccnd2
cyclin D2
affects methylation multiple interactions
ISO
Azacitidine affects the methylation of CCND2 promoter [Azacitidine affects the methylation of CCND2 promoter] which affects the expression of CCND2 mRNA
CTD
PMID:17016690
NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
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Ccng2
cyclin G2
decreases expression
ISO
Azacitidine results in decreased expression of CCNG2 mRNA
CTD
PMID:21245298
NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
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Cd274
CD274 antigen
multiple interactions
ISO
Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]
CTD
PMID:32894642
NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
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Cdc20
cell division cycle 20
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA
CTD
PMID:18720364
NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
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Cdc42bpa
CDC42 binding protein kinase alpha
decreases expression
ISO
Azacitidine results in decreased expression of CDC42BPA mRNA
CTD
PMID:20823114
NCBI chr 1:179,787,058...179,993,171
Ensembl chr 1:179,788,037...179,993,168
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Cdh1
cadherin 1
decreases methylation increases expression
ISO
Azacitidine results in decreased methylation of CDH1 promoter Azacitidine results in increased expression of CDH1 mRNA
CTD
PMID:17520682
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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Cdh2
cadherin 2
increases expression
ISO
Azacitidine results in increased expression of CDH2 mRNA
CTD
PMID:18037191
NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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Cdk1
cyclin dependent kinase 1
multiple interactions increases expression
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA Azacitidine analog results in increased expression of CDK1 protein
CTD
PMID:18324645 PMID:18720364
NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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Cdk2
cyclin dependent kinase 2
decreases expression
ISO
Azacitidine analog results in decreased expression of CDK2 protein
CTD
PMID:18324645
NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
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Cdk4
cyclin dependent kinase 4
decreases expression
ISO
Azacitidine analog results in decreased expression of CDK4 protein
CTD
PMID:18324645
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
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Cdkn1a
cyclin dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
Azacitidine analog results in increased expression of CDKN1A protein; Azacitidine results in increased expression of CDKN1A mRNA [metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A [Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
CTD
PMID:18324645 PMID:19148494 PMID:20823114 PMID:21224363 PMID:25015661
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cdkn1c
cyclin dependent kinase inhibitor 1C
increases expression
ISO
Azacitidine results in increased expression of CDKN1C mRNA
CTD
PMID:19194470
NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787
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Cdkn2a
cyclin dependent kinase inhibitor 2A
affects methylation decreases methylation multiple interactions increases expression
ISO EXP
Azacitidine affects the methylation of CDKN2A gene Azacitidine results in decreased methylation of CDKN2A gene Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene] [Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene; [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA Azacitidine results in increased expression of CDKN2A mRNA Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter]
CTD
PMID:17686055 PMID:18443271 PMID:21224363 PMID:22355787
NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
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Cdkn2b
cyclin dependent kinase inhibitor 2B
decreases methylation affects response to substance multiple interactions
ISO
Azacitidine results in decreased methylation of CDKN2B promoter CDKN2B promoter modified form affects the susceptibility to Azacitidine [metacept-1 co-treated with Azacitidine] results in increased expression of CDKN2B
CTD
PMID:17611569 PMID:19148494 PMID:19194470
NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
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Cebpa
CCAAT/enhancer binding protein alpha
decreases methylation increases expression
ISO
Azacitidine results in decreased methylation of CEBPA promoter Azacitidine results in increased expression of CEBPA mRNA
CTD
PMID:19194470 PMID:27590069
NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
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Cenpa
centromere protein A
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA
CTD
PMID:18720364
NCBI chr 5:30,824,214...30,832,181
Ensembl chr 5:30,824,121...30,832,174
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Cenpf
centromere protein F
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA
CTD
PMID:18720364
NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283
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Cenpo
centromere protein O
increases expression
ISO
Azacitidine results in increased expression of CENPO mRNA
CTD
PMID:19194470
NCBI chr12:4,243,548...4,284,255
Ensembl chr12:4,246,004...4,284,294
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Chat
choline acetyltransferase
increases expression
EXP
Azacitidine results in increased expression of CHAT mRNA; Azacitidine results in increased expression of CHAT protein
CTD
PMID:19151599
NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
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Chga
chromogranin A
decreases expression
ISO
Azacitidine results in decreased expression of CHGA protein
CTD
PMID:20607034
NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
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Chit1
chitinase 1
increases expression
ISO
Azacitidine results in increased expression of CHIT1 mRNA
CTD
PMID:20823114
NCBI chr 1:134,038,980...134,079,279
Ensembl chr 1:134,038,980...134,079,278
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Chrm1
cholinergic receptor, muscarinic 1, CNS
affects expression
EXP
Azacitidine affects the expression of CHRM1 mRNA
CTD
PMID:19002953
NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
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Chrm2
cholinergic receptor, muscarinic 2, cardiac
affects expression
EXP
Azacitidine affects the expression of CHRM2 mRNA
CTD
PMID:19002953
NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
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Chst14
carbohydrate sulfotransferase 14
increases expression
ISO
Azacitidine results in increased expression of CHST14 mRNA
CTD
PMID:27415467
NCBI chr 2:118,756,978...118,759,066
Ensembl chr 2:118,756,977...118,759,066
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Ciita
class II transactivator
multiple interactions increases expression
ISO
[Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA] Azacitidine results in increased expression of CIITA mRNA
CTD
PMID:18829986 PMID:20823114
NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
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Cldn10
claudin 10
decreases expression
ISO
Azacitidine results in decreased expression of CLDN10 mRNA
CTD
PMID:19194470
NCBI chr14:119,025,283...119,111,937
Ensembl chr14:119,025,320...119,112,901
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Cldn6
claudin 6
increases expression multiple interactions decreases methylation
ISO
Azacitidine results in increased expression of CLDN6 mRNA [trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter Azacitidine results in decreased methylation of CLDN6 promoter
CTD
PMID:18661270
NCBI chr17:23,898,345...23,901,417
Ensembl chr17:23,898,223...23,901,420
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Cldn7
claudin 7
decreases expression multiple interactions
ISO
Azacitidine results in decreased expression of CLDN7 mRNA Cisplatin affects the reaction [Azacitidine results in decreased expression of CLDN7 mRNA]
CTD
PMID:36336710
NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711
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Cldn8
claudin 8
increases expression
ISO
Azacitidine results in increased expression of CLDN8 mRNA
CTD
PMID:18661270
NCBI chr16:88,357,714...88,360,071
Ensembl chr16:88,357,716...88,360,071
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Cldn9
claudin 9
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of CLDN9 promoter Azacitidine results in increased expression of CLDN9 mRNA [trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter
CTD
PMID:18661270
NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000
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Cnnm2
cyclin M2
decreases expression
ISO
Azacitidine results in decreased expression of CNNM2 mRNA
CTD
PMID:19194470
NCBI chr19:46,745,273...46,867,019
Ensembl chr19:46,750,035...46,868,631
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Col14a1
collagen, type XIV, alpha 1
increases expression
ISO
Azacitidine results in increased expression of COL14A1 mRNA
CTD
PMID:19194470
NCBI chr15:55,171,040...55,384,199
Ensembl chr15:55,171,146...55,384,199
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Col1a1
collagen, type I, alpha 1
multiple interactions
ISO
Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]
CTD
PMID:22841775
NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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Col6a3
collagen, type VI, alpha 3
decreases expression
ISO
Azacitidine results in decreased expression of COL6A3 mRNA
CTD
PMID:20823114
NCBI chr 1:90,694,582...90,771,710
Ensembl chr 1:90,693,645...90,771,693
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Col9a3
collagen, type IX, alpha 3
decreases expression
EXP
Azacitidine results in decreased expression of COL9A3 mRNA
CTD
PMID:18033690
NCBI chr 2:180,239,895...180,263,985
Ensembl chr 2:180,239,583...180,263,982
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Cox6a2
cytochrome c oxidase subunit 6A2
increases expression
ISO
Azacitidine results in increased expression of COX6A2 mRNA
CTD
PMID:20823114
NCBI chr 7:127,804,607...127,805,538
Ensembl chr 7:127,804,607...127,805,559
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Cpe
carboxypeptidase E
increases expression
ISO
Azacitidine results in increased expression of CPE mRNA
CTD
PMID:20823114
NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
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Cplx1
complexin 1
increases expression
ISO
Azacitidine results in increased expression of CPLX1 mRNA
CTD
PMID:20823114
NCBI chr 5:108,666,420...108,697,893
Ensembl chr 5:108,666,420...108,697,890
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Creb1
cAMP responsive element binding protein 1
multiple interactions
ISO
Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter]
CTD
PMID:19155497
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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Creb3l4
cAMP responsive element binding protein 3-like 4
increases expression
ISO
Azacitidine results in increased expression of CREB3L4 mRNA
CTD
PMID:27415467
NCBI chr 3:90,144,805...90,161,387
Ensembl chr 3:90,144,807...90,150,819
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Crem
cAMP responsive element modulator
decreases expression
ISO
Azacitidine results in decreased expression of CREM mRNA
CTD
PMID:20823114
NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
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Cryaa
crystallin, alpha A
increases expression
ISO
Azacitidine results in increased expression of CRYAA protein
CTD
PMID:17105402
NCBI chr17:31,896,905...31,900,704
Ensembl chr17:31,896,781...31,900,707
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Cryab
crystallin, alpha B
increases expression
ISO
Azacitidine results in increased expression of CRYAB protein
CTD
PMID:17105402
NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
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Csf1
colony stimulating factor 1 (macrophage)
increases expression
ISO
Azacitidine results in increased expression of CSF1 mRNA
CTD
PMID:17156202
NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
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Csn1s1
casein alpha s1
increases expression
ISO
Azacitidine results in increased expression of CSN1S1 mRNA
CTD
PMID:20823114
NCBI chr 5:87,814,067...87,830,437
Ensembl chr 5:87,814,067...87,830,437
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Cst3
cystatin C
increases expression
ISO
Azacitidine results in increased expression of CST3 mRNA
CTD
PMID:20823114
NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
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Cxcl12
C-X-C motif chemokine ligand 12
decreases methylation increases expression
ISO
Azacitidine results in decreased methylation of CXCL12 promoter Azacitidine results in increased expression of CXCL12 mRNA; Azacitidine results in increased expression of CXCL12 protein
CTD
PMID:19748759
NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression
ISO EXP
Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Azacitidine results in increased expression of CYP1A1 mRNA [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]
CTD
PMID:11281733 PMID:12927368 PMID:17682057 PMID:27590069
NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions increases expression
ISO
Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] Azacitidine results in increased expression of CYP1A2 mRNA
CTD
PMID:12927368
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions increases expression
ISO
Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Azacitidine results in increased expression of CYP1B1 mRNA
CTD
PMID:12927368 PMID:27590069
NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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Cyth1
cytohesin 1
increases expression
ISO
Azacitidine results in increased expression of CYTH1 mRNA
CTD
PMID:19194470
NCBI chr11:118,054,996...118,139,452
Ensembl chr11:118,022,845...118,139,386
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Dapk1
death associated protein kinase 1
affects methylation
ISO
Azacitidine affects the methylation of DAPK1 promoter
CTD
PMID:17557868
NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
G
Dcn
decorin
multiple interactions decreases expression
ISO
Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein] Azacitidine results in decreased expression of DCN mRNA
CTD
PMID:20823114
NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
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Des
desmin
increases expression multiple interactions
ISO
Azacitidine results in increased expression of DES mRNA; Azacitidine results in increased expression of DES protein [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA
CTD
PMID:18037191 PMID:20823114
NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
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Dhx9
DExH-box helicase 9
decreases expression
ISO
Azacitidine results in decreased expression of DHX9 mRNA
CTD
PMID:20823114
NCBI chr 1:153,331,506...153,363,464
Ensembl chr 1:153,331,504...153,363,406
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Dio2
deiodinase, iodothyronine, type II
decreases expression
ISO
Azacitidine results in decreased expression of DIO2 mRNA
CTD
PMID:20823114
NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
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Dlk1
delta like non-canonical Notch ligand 1
decreases methylation
ISO
Azacitidine results in decreased methylation of DLK1 promoter
CTD
PMID:19194470
NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
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Dlx5
distal-less homeobox 5
increases expression
EXP
Azacitidine results in increased expression of DLX5 mRNA
CTD
PMID:17085970
NCBI chr 6:6,877,801...6,882,068
Ensembl chr 6:6,877,805...6,882,085
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Dlx6
distal-less homeobox 6
increases expression
ISO
Azacitidine results in increased expression of DLX6 mRNA
CTD
PMID:20823114
NCBI chr 6:6,863,272...6,867,965
Ensembl chr 6:6,863,334...6,868,568
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Dnmt1
DNA methyltransferase 1
multiple interactions decreases expression
ISO
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]; Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter] [Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein; [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein
CTD
PMID:19139132 PMID:19723570 PMID:21224363 PMID:28901456 PMID:35066776
NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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Dnmt3a
DNA methyltransferase 3A
multiple interactions
ISO
Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]
CTD
PMID:35066776
NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
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Dnmt3b
DNA methyltransferase 3B
multiple interactions
ISO
Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter]
CTD
PMID:35066776
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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Dpyd
dihydropyrimidine dehydrogenase
decreases methylation decreases response to substance multiple interactions
ISO
Azacitidine results in decreased methylation of DPYD promoter DPYD protein results in decreased susceptibility to Azacitidine [Azacitidine results in decreased methylation of DPYD promoter] which results in increased expression of DPYD mRNA
CTD
PMID:15501990
NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573
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Dusp1
dual specificity phosphatase 1
increases expression
ISO
Azacitidine results in increased expression of DUSP1 mRNA
CTD
PMID:20823114
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp6
dual specificity phosphatase 6
increases expression
ISO
Azacitidine results in increased expression of DUSP6 mRNA
CTD
PMID:21245298
NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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E2f1
E2F transcription factor 1
multiple interactions
ISO
E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
CTD
PMID:19451745
NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
G
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
decreases expression
ISO
Azacitidine results in decreased expression of EEF1A1 mRNA
CTD
PMID:20823114
NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433
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Efna3
ephrin A3
increases expression
ISO
Azacitidine results in increased expression of EFNA3 mRNA
CTD
PMID:20823114
NCBI chr 3:89,221,200...89,231,359
Ensembl chr 3:89,221,206...89,230,272
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Egr2
early growth response 2
increases expression
ISO
Azacitidine results in increased expression of EGR2 mRNA
CTD
PMID:20823114
NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
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Eno2
enolase 2, gamma neuronal
decreases expression
ISO
Azacitidine results in decreased expression of ENO2 protein
CTD
PMID:20607034
NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636
G
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
increases expression
ISO
Azacitidine results in increased expression of ENTPD1 mRNA
CTD
PMID:20823114
NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046
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Esr1
estrogen receptor 1 (alpha)
increases expression
ISO
Azacitidine results in increased expression of ESR1 protein
CTD
PMID:22558281
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
G
Ets1
E26 avian leukemia oncogene 1, 5' domain
multiple interactions
ISO
Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter]
CTD
PMID:18945643
NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
G
Eya1
EYA transcriptional coactivator and phosphatase 1
decreases expression
ISO
Azacitidine results in decreased expression of EYA1 mRNA
CTD
PMID:20823114
NCBI chr 1:14,239,177...14,381,259
Ensembl chr 1:14,239,178...14,380,459
G
Fads2
fatty acid desaturase 2
decreases expression
ISO
Azacitidine results in decreased expression of FADS2 mRNA
CTD
PMID:20823114
NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
G
Fam8a1
family with sequence similarity 8, member A1
increases expression
ISO
Azacitidine results in increased expression of FAM8A1 mRNA
CTD
PMID:19194470
NCBI chr13:46,822,953...46,831,540
Ensembl chr13:46,822,998...46,831,532
G
Fasl
Fas ligand
increases response to substance
EXP ISO
Azacitidine results in increased susceptibility to FASLG protein
CTD
PMID:18829727
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
G
Fbln1
fibulin 1
increases expression
ISO
Azacitidine results in increased expression of FBLN1 mRNA
CTD
PMID:21245298
NCBI chr15:85,090,150...85,170,495
Ensembl chr15:85,090,150...85,170,736
G
Fen1
flap structure specific endonuclease 1
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA
CTD
PMID:18720364
NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
G
Fgf7
fibroblast growth factor 7
decreases expression
ISO
Azacitidine results in decreased expression of FGF7 mRNA
CTD
PMID:20823114
NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105
G
Filip1l
filamin A interacting protein 1-like
decreases expression
ISO
Azacitidine results in decreased expression of FILIP1L mRNA
CTD
PMID:20823114
NCBI chr16:57,173,376...57,393,167
Ensembl chr16:57,173,456...57,393,489
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Foxo1
forkhead box O1
multiple interactions
ISO
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA
CTD
PMID:20823114
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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Foxp3
forkhead box P3
multiple interactions
EXP
[Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein; [Azacitidine results in decreased methylation of FOXP3 gene] which results in increased expression of FOXP3 protein
CTD
PMID:18493985
NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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Ftl1
ferritin light polypeptide 1
decreases expression
ISO
Azacitidine results in decreased expression of FTL1 protein
CTD
PMID:17105402
NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
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Fyn
Fyn proto-oncogene
increases expression
ISO
Azacitidine results in increased expression of FYN mRNA
CTD
PMID:21245298
NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
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Gabrb1
gamma-aminobutyric acid type A receptor subunit beta 1
increases expression
ISO
Azacitidine results in increased expression of GABRB1 mRNA
CTD
PMID:19194470
NCBI chr 5:71,815,264...72,306,915
Ensembl chr 5:71,815,456...72,306,380
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Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of GADD45A promoter Azacitidine results in increased expression of GADD45A mRNA; Azacitidine results in increased expression of GADD45A protein [Azacitidine results in increased expression of GADD45A protein] which results in increased susceptibility to docetaxel
CTD
PMID:19190346
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
G
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
multiple interactions
ISO
Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B]
CTD
PMID:18225533
NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
G
Gata4
GATA binding protein 4
increases expression
ISO
Azacitidine results in increased expression of GATA4 mRNA; Azacitidine results in increased expression of GATA4 protein
CTD
PMID:18037191
NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
G
Gbp2
guanylate binding protein 2
decreases expression
ISO
Azacitidine results in decreased expression of GBP2 mRNA
CTD
PMID:20823114
NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769
G
Gcnt2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
decreases expression
ISO
Azacitidine results in decreased expression of GCNT2 mRNA
CTD
PMID:20823114
NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
G
Gdf9
growth differentiation factor 9
increases expression
EXP
Azacitidine results in increased expression of GDF9 mRNA
CTD
PMID:23395740
NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
G
Gja1
gap junction protein, alpha 1
increases expression decreases expression
ISO
Azacitidine results in increased expression of GJA1 protein Azacitidine results in decreased expression of GJA1 mRNA
CTD
PMID:18037191 PMID:20823114
NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
G
Gm40318
predicted gene, 40318
increases expression
ISO
Azacitidine results in increased expression of S100P mRNA
CTD
PMID:19194470
NCBI chr 5:36,919,848...36,924,763
Ensembl chr 5:36,919,961...36,924,039
G
Gng7
guanine nucleotide binding protein (G protein), gamma 7
affects methylation
ISO
Azacitidine affects the methylation of GNG7 promoter
CTD
PMID:18219292
NCBI chr10:80,784,463...80,850,742
Ensembl chr10:80,784,458...80,850,779
G
Gpkow
G patch domain and KOW motifs
increases expression
ISO
Azacitidine results in increased expression of GPKOW mRNA
CTD
PMID:20823114
NCBI chr X:7,563,373...7,576,500
Ensembl chr X:7,563,370...7,576,501
G
Gpnmb
glycoprotein (transmembrane) nmb
decreases expression
ISO
Azacitidine results in decreased expression of GPNMB mRNA
CTD
PMID:20823114
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
5-azacytidine increases expression of GPX3 mRNA in epithelial cells of stomach
RGD
PMID:16229808
RGD:151665354
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
decreases methylation
EXP
Azacitidine results in decreased methylation of GRIN2B gene
CTD
PMID:18618247
NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
G
Guk1
guanylate kinase 1
increases expression
ISO
Azacitidine results in increased expression of GUK1 mRNA
CTD
PMID:20823114
NCBI chr11:59,074,696...59,083,068
Ensembl chr11:59,074,701...59,083,069
G
Gzmb
granzyme B
multiple interactions
ISO
Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]
CTD
PMID:19394699
NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
G
H1f0
H1.0 linker histone
increases expression
ISO
Azacitidine results in increased expression of H1-0 protein
CTD
PMID:16006241
NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704
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H2-Ea
histocompatibility 2, class II antigen E alpha
multiple interactions
ISO
[Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein
CTD
PMID:18829986
NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618
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H2-K1
histocompatibility 2, K1, K region
multiple interactions
EXP
Azacitidine inhibits the reaction [Tretinoin results in increased expression of H2-K1 protein]
CTD
PMID:6197180
NCBI chr17:34,214,986...34,219,316
Ensembl chr17:34,214,991...34,219,321
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H2ax
H2A.X variant histone
increases expression multiple interactions
ISO
Azacitidine results in increased expression of H2AX protein Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]
CTD
PMID:17991895 PMID:25015661
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
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H3f4
H3.4 histone, cluster member
multiple interactions
ISO
Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]
CTD
PMID:17698632
NCBI chr11:58,852,537...58,853,099
Ensembl chr11:58,852,599...58,853,364
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H4c16
H4 histone 16
multiple interactions
ISO
Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter]
CTD
PMID:17698632
NCBI chr 6:136,780,991...136,781,429
Ensembl chr 6:136,778,551...136,781,413
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Hgd
homogentisate 1, 2-dioxygenase
increases expression
ISO
Azacitidine results in increased expression of HGD mRNA
CTD
PMID:20823114
NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382
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Hgf
hepatocyte growth factor
increases expression
ISO
Azacitidine results in increased expression of HGF mRNA
CTD
PMID:19194470
NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
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Hhex
hematopoietically expressed homeobox
increases expression
ISO
Azacitidine results in increased expression of HHEX mRNA
CTD
PMID:27590069
NCBI chr19:37,423,289...37,429,179
Ensembl chr19:37,423,258...37,429,179
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Hmga1
high mobility group AT-hook 1
increases expression
ISO
Azacitidine results in increased expression of HMGA1 mRNA
CTD
PMID:20823114
NCBI chr17:27,774,798...27,782,649
Ensembl chr17:27,775,471...27,782,648
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Hmga2
high mobility group AT-hook 2
increases expression multiple interactions
ISO
Azacitidine results in increased expression of HMGA2 mRNA TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]
CTD
PMID:21245298
NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
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Hmgb1
high mobility group box 1
decreases expression multiple interactions
EXP
Azacitidine results in decreased expression of HMGB1 mRNA Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD
PMID:32278510
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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Hnf1a
HNF1 homeobox A
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of HNF1A promoter Azacitidine results in increased expression of HNF1A mRNA; Azacitidine results in increased expression of HNF1A protein HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
CTD
PMID:25953102
NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153
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Hnf4a
hepatic nuclear factor 4, alpha
increases expression
ISO
Azacitidine results in increased expression of HNF4A mRNA
CTD
PMID:27590069
NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
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Hoxa1
homeobox A1
multiple interactions increases expression
ISO
Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA] Azacitidine results in increased expression of HOXA1 mRNA
CTD
PMID:20823114
NCBI chr 6:52,132,573...52,135,299
Ensembl chr 6:52,132,570...52,135,297
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Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of HPGD gene Azacitidine results in increased expression of HPGD mRNA trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA]
CTD
PMID:19584167
NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078
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Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
affects expression
EXP
Azacitidine affects the expression of HSD3B1 mRNA
CTD
PMID:18033690
NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
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Hsf1
heat shock factor 1
decreases activity
ISO
Azacitidine results in decreased activity of HSF1 protein
CTD
PMID:34170685
NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
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Id1
inhibitor of DNA binding 1, HLH protein
increases expression
ISO
Azacitidine results in increased expression of ID1 mRNA
CTD
PMID:19194470
NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
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Id3
inhibitor of DNA binding 3
increases expression
ISO
Azacitidine results in increased expression of ID3 mRNA
CTD
PMID:19194470
NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
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Ifng
interferon gamma
multiple interactions
ISO
[Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]; [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein
CTD
PMID:18829986 PMID:18945643
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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Igfbp1
insulin-like growth factor binding protein 1
multiple interactions increases expression
ISO
Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein] Azacitidine results in increased expression of IGFBP1 mRNA
CTD
PMID:20823114
NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
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Igfbp4
insulin-like growth factor binding protein 4
increases expression
ISO
Azacitidine results in increased expression of IGFBP4 mRNA
CTD
PMID:20823114
NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
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Il12b
interleukin 12b
increases expression
ISO
Azacitidine results in increased expression of IL12B mRNA
CTD
PMID:20823114
NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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Il1b
interleukin 1 beta
increases expression multiple interactions
ISO
Azacitidine results in increased expression of IL1B mRNA Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]
CTD
PMID:17156202 PMID:32894642
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il2
interleukin 2
multiple interactions
ISO
Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]; Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein]
CTD
PMID:19394699
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il4
interleukin 4
affects methylation
ISO
Azacitidine affects the methylation of IL4 promoter
CTD
PMID:18158872
NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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Il6
interleukin 6
affects secretion affects methylation
ISO
Azacitidine affects the secretion of IL6 protein Azacitidine affects the methylation of IL6 promoter
CTD
PMID:18158872 PMID:18443271
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Il6ra
interleukin 6 receptor, alpha
affects expression multiple interactions
ISO
[Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein; Azacitidine affects the expression of IL6R mRNA [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein
CTD
PMID:18443271
NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
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Isca1
iron-sulfur cluster assembly 1
increases expression
ISO
Azacitidine results in increased expression of ISCA1 mRNA
CTD
PMID:19194470
NCBI chr13:59,903,229...59,917,603
Ensembl chr13:59,903,223...59,917,624
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Itgb1
integrin beta 1 (fibronectin receptor beta)
decreases expression
ISO
Azacitidine results in decreased expression of ITGB1 mRNA
CTD
PMID:20823114
NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
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Itgb2
integrin beta 2
decreases expression
ISO
Azacitidine results in decreased expression of ITGB2 mRNA
CTD
PMID:19194470
NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
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Itprid2
ITPR interacting domain containing 2
increases expression
ISO
Azacitidine results in increased expression of ITPRID2 mRNA
CTD
PMID:20823114
NCBI chr 2:79,419,207...79,503,310
Ensembl chr 2:79,465,696...79,503,310
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Kdr
kinase insert domain protein receptor
increases expression
ISO
Azacitidine results in increased expression of KDR mRNA
CTD
PMID:18037191
NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
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Kif2c
kinesin family member 2C
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA
CTD
PMID:18720364
NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
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Klf6
Kruppel-like transcription factor 6
increases expression multiple interactions
ISO
Azacitidine results in increased expression of KLF6 mRNA TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]
CTD
PMID:21245298
NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
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Krt19
keratin 19
increases expression
ISO
Azacitidine results in increased expression of KRT19 mRNA
CTD
PMID:20823114
NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
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Krt32
keratin 32
increases expression
ISO
Azacitidine results in increased expression of KRT32 mRNA
CTD
PMID:20823114
NCBI chr11:99,971,674...99,979,095
Ensembl chr11:99,971,674...99,979,100
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Krt8
keratin 8
increases expression multiple interactions
ISO
Azacitidine results in increased expression of KRT8 mRNA Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]
CTD
PMID:20823114
NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
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Lama1
laminin, alpha 1
affects localization
EXP
Azacitidine affects the localization of LAMA1 protein
CTD
PMID:18033690
NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
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Lamb2
laminin, beta 2
increases expression
ISO
Azacitidine results in increased expression of LAMB2 mRNA
CTD
PMID:20823114
NCBI chr 9:108,357,080...108,367,729
Ensembl chr 9:108,356,935...108,367,729
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Lcn11
lipocalin 11
decreases expression
ISO
Azacitidine results in decreased expression of PAEP mRNA
CTD
PMID:20823114
NCBI chr 2:25,667,029...25,670,291
Ensembl chr 2:25,667,029...25,670,291
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Ldhb
lactate dehydrogenase B
increases expression
ISO
Azacitidine results in increased expression of LDHB mRNA
CTD
PMID:23437403
NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
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Lims1
LIM and senescent cell antigen-like domains 1
increases expression
ISO
Azacitidine results in increased expression of LIMS1 mRNA
CTD
PMID:19194470
NCBI chr10:58,159,164...58,260,513
Ensembl chr10:58,159,288...58,260,513
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Litaf
LPS-induced TN factor
decreases expression
ISO
Azacitidine results in decreased expression of LITAF mRNA
CTD
PMID:19194470
NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021
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Ltb4r1
leukotriene B4 receptor 1
decreases expression
ISO
Azacitidine results in decreased expression of LTB4R mRNA
CTD
PMID:20823114
NCBI chr14:56,002,154...56,005,951
Ensembl chr14:56,003,419...56,005,951
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Lyz2
lysozyme 2
increases expression
ISO
Azacitidine results in increased expression of LYZ mRNA
CTD
PMID:19194470
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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Mad1l1
MAD1 mitotic arrest deficient 1-like 1
decreases expression
ISO
Azacitidine results in decreased expression of MAD1L1 mRNA
CTD
PMID:19194470
NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307
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Mafb
MAF bZIP transcription factor B
increases expression multiple interactions
ISO
Azacitidine results in increased expression of MAFB mRNA Cisplatin affects the reaction [Azacitidine results in increased expression of MAFB mRNA]
CTD
PMID:36336710
NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985
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Magea3
MAGE family member A3
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of MAGEA3 promoter Azacitidine results in increased expression of MAGEA3 mRNA; Azacitidine results in increased expression of MAGEA3 protein [Azacitidine results in decreased methylation of MAGEA3 promoter] which results in increased expression of MAGEA3 mRNA; mocetinostat promotes the reaction [Azacitidine results in increased expression of MAGEA3 mRNA]; mocetinostat promotes the reaction [Azacitidine results in increased expression of MAGEA3 protein]
CTD
PMID:21171821
NCBI chr X:153,731,176...153,742,027
Ensembl chr X:153,731,539...153,732,501
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Magea5
MAGE family member A5
decreases methylation multiple interactions
ISO
Azacitidine results in decreased methylation of MAGEA1 gene Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of MAGEA1 gene]
CTD
PMID:17686055
NCBI chr X:153,836,057...153,846,147
Ensembl chr X:153,836,057...153,846,141
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Map1a
microtubule-associated protein 1 A
decreases expression
ISO
Azacitidine results in decreased expression of MAP1A mRNA
CTD
PMID:20823114
NCBI chr 2:121,119,608...121,141,313
Ensembl chr 2:121,120,081...121,141,313
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Map2k5
mitogen-activated protein kinase kinase 5
decreases expression
ISO
Azacitidine results in decreased expression of MAP2K5 mRNA
CTD
PMID:20823114
NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184
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Mapt
microtubule-associated protein tau
decreases expression
ISO
Azacitidine results in decreased expression of MAPT protein
CTD
PMID:16930453
NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
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Mcl1
myeloid cell leukemia sequence 1
decreases expression
ISO
5-azacytidine decreases expression of MCL1 protein in lung cancer cells
RGD
PMID:24356455
RGD:153344603
NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
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Mcm5
minichromosome maintenance complex component 5
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA
CTD
PMID:18720364
NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
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Mdc1
mediator of DNA damage checkpoint 1
increases expression
ISO
Azacitidine results in increased expression of MDC1 mRNA
CTD
PMID:20823114
NCBI chr17:36,152,390...36,170,562
Ensembl chr17:36,152,407...36,170,562
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Mdm2
transformed mouse 3T3 cell double minute 2
increases expression
ISO
Azacitidine results in increased expression of MDM2 mRNA
CTD
PMID:20823114
NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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Mecp2
methyl CpG binding protein 2
multiple interactions
ISO
Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]
CTD
PMID:17698632
NCBI chr X:73,070,198...73,129,296
Ensembl chr X:73,070,198...73,129,296
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Mef2a
myocyte enhancer factor 2A
increases expression affects expression
EXP
Azacitidine results in increased expression of MEF2A Azacitidine affects the expression of MEF2A protein
CTD
PMID:12094073 PMID:19002953
NCBI chr 7:66,880,911...67,026,435
Ensembl chr 7:66,880,911...67,022,606
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Mef2d
myocyte enhancer factor 2D
affects expression increases expression
EXP
Azacitidine affects the expression of MEF2D protein Azacitidine results in increased expression of MEF2D
CTD
PMID:12094073 PMID:19002953
NCBI chr 3:88,049,248...88,079,398
Ensembl chr 3:88,049,679...88,079,393
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Megf6
multiple EGF-like-domains 6
decreases expression
ISO
Azacitidine results in decreased expression of MEGF6 mRNA
CTD
PMID:19194470
NCBI chr 4:154,255,156...154,360,178
Ensembl chr 4:154,255,187...154,360,170
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Mesd
mesoderm development LRP chaperone
decreases expression
ISO
Azacitidine results in decreased expression of MESD protein
CTD
PMID:17105402
NCBI chr 7:83,533,074...83,549,519
Ensembl chr 7:83,533,674...83,550,740
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Mfap2
microfibrillar-associated protein 2
decreases expression
ISO
Azacitidine results in decreased expression of MFAP2 mRNA
CTD
PMID:20823114
NCBI chr 4:140,737,735...140,743,284
Ensembl chr 4:140,737,729...140,743,295
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Mfge8
milk fat globule EGF and factor V/VIII domain containing
affects expression
EXP
Azacitidine affects the expression of MFGE8 mRNA
CTD
PMID:18033690
NCBI chr 7:78,783,516...78,798,808
Ensembl chr 7:78,783,516...78,798,808
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Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression decreases methylation
ISO
Azacitidine results in increased expression of MGMT mRNA Azacitidine results in decreased methylation of MGMT protein
CTD
PMID:7511991 PMID:12807730
NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
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Mir193a
microRNA 193a
increases expression
ISO
5-azacytidine increases expression of MIR193A in liver cells 5-azacytidine increases expression of MIR193a RNA in lung cancer cells
RGD
PMID:28036298 PMID:24356455
RGD:153344564 , RGD:153344603
NCBI chr11:79,602,795...79,602,860
Ensembl chr11:79,602,795...79,602,860
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Mir23b
microRNA 23b
increases expression
ISO
5-azacytidine increases expression of MIR23B miRNA in liver cells
RGD
PMID:28036298
RGD:153344564
NCBI chr13:63,448,298...63,448,371
Ensembl chr13:63,448,298...63,448,371
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Mir497
microRNA 497
multiple interactions increases expression decreases methylation
ISO
Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter] Azacitidine results in increased expression of MIR497 mRNA Azacitidine results in decreased methylation of MIR497 promoter
CTD
PMID:35066776
NCBI chr11:70,125,543...70,125,626
Ensembl chr11:70,125,543...70,125,626
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Mir9-3
microRNA 9-3
increases expression
ISO
5-azacytidine increases expression of MIR9-3 in lung cancer cells
RGD
PMID:24356455
RGD:153344603
NCBI chr 7:79,155,012...79,155,101
Ensembl chr 7:79,155,012...79,155,101
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Mki67
antigen identified by monoclonal antibody Ki 67
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA
CTD
PMID:18720364
NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
G
Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
increases expression
ISO
Azacitidine results in increased expression of MMP1 mRNA
CTD
PMID:20823114
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
metacept-1 inhibits the reaction [Azacitidine results in increased expression of MMP9]
CTD
PMID:19148494
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Morf4l2
mortality factor 4 like 2
decreases expression
ISO
Azacitidine results in decreased expression of MORF4L2 mRNA
CTD
PMID:20823114
NCBI chr X:135,633,691...135,644,435
Ensembl chr X:135,633,691...135,644,439
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Mov10l1
Mov10 like RISC complex RNA helicase 1
increases expression
ISO
Azacitidine results in increased expression of MOV10L1 mRNA
CTD
PMID:20823114
NCBI chr15:88,867,094...88,939,355
Ensembl chr15:88,867,112...88,939,355
G
Msrb2
methionine sulfoxide reductase B2
increases expression
ISO
Azacitidine results in increased expression of MSRB2 mRNA
CTD
PMID:19194470
NCBI chr 2:19,376,247...19,399,787
Ensembl chr 2:19,376,251...19,399,787
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Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
decreases expression
ISO
Azacitidine results in decreased expression of MTHFD2 mRNA
CTD
PMID:20823114
NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
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Mtrex
Mtr4 exosome RNA helicase
increases expression
ISO
Azacitidine results in increased expression of MTREX mRNA
CTD
PMID:20823114
NCBI chr13:113,004,306...113,063,914
Ensembl chr13:113,003,952...113,063,932
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Myc
myelocytomatosis oncogene
decreases expression multiple interactions
ISO
Azacitidine analog results in decreased expression of MYC mRNA MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
CTD
PMID:18045574 PMID:19451745
NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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Myf5
myogenic factor 5
increases expression
EXP
Azacitidine results in increased expression of MYF5 mRNA
CTD
PMID:18938140
NCBI chr10:107,318,769...107,322,787
Ensembl chr10:107,318,769...107,321,995
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Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
increases expression
ISO
Azacitidine results in increased expression of MYH7 mRNA; Azacitidine results in increased expression of MYH7 protein
CTD
PMID:17105402
NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
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Myl2
myosin, light polypeptide 2, regulatory, cardiac, slow
increases expression
ISO
Azacitidine results in increased expression of MYL2 mRNA
CTD
PMID:17105402
NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535
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Myod1
myogenic differentiation 1
increases expression
ISO EXP
Azacitidine results in increased expression of MYOD1 mRNA
CTD
PMID:18037191 PMID:18938140
NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523
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Myog
myogenin
increases expression
EXP
Azacitidine results in increased expression of MYOG mRNA
CTD
PMID:18938140
NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286
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Ncam1
neural cell adhesion molecule 1
increases expression
ISO
Azacitidine results in increased expression of NCAM1 mRNA
CTD
PMID:18037191
NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225
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Nefl
neurofilament, light polypeptide
increases expression
ISO
Azacitidine results in increased expression of NEFL mRNA
CTD
PMID:20823114
NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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Nfatc1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
increases expression
ISO
Azacitidine results in increased expression of NFATC1 mRNA
CTD
PMID:20823114
NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
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Niban1
niban apoptosis regulator 1
increases expression multiple interactions
ISO
Azacitidine results in increased expression of NIBAN1 mRNA TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]
CTD
PMID:21245298
NCBI chr 1:151,447,215...151,597,690
Ensembl chr 1:151,446,937...151,597,690
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Nkx2-5
NK2 homeobox 5
increases expression
ISO
Azacitidine results in increased expression of NKX2-5 mRNA
CTD
PMID:18557828
NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983
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Nlgn3
neuroligin 3
increases expression
ISO
Azacitidine results in increased expression of NLGN3 mRNA
CTD
PMID:20823114
NCBI chr X:100,342,785...100,364,956
Ensembl chr X:100,342,774...100,369,569
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
increases expression
ISO
Azacitidine results in increased expression of NME2 protein
CTD
PMID:17105402
NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
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Nmi
N-myc (and STAT) interactor
increases expression
ISO
Azacitidine results in increased expression of NMI mRNA
CTD
PMID:21245298
NCBI chr 2:51,838,517...51,863,241
Ensembl chr 2:51,838,499...51,863,506
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Nnt
nicotinamide nucleotide transhydrogenase
increases expression
ISO
Azacitidine results in increased expression of NNT mRNA; Azacitidine results in increased expression of NNT protein
CTD
PMID:36336710
NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533 Ensembl chr13:119,471,984...119,545,533
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Nom1
nucleolar protein with MIF4G domain 1
decreases expression
ISO
Azacitidine results in decreased expression of NOM1 mRNA
CTD
PMID:20823114
NCBI chr 5:29,637,338...29,658,504
Ensembl chr 5:29,639,662...29,662,841
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Nphp1
nephronophthisis 1 (juvenile) homolog (human)
increases expression
ISO
Azacitidine results in increased expression of NPHP1 mRNA
CTD
PMID:20823114
NCBI chr 2:127,582,652...127,630,833
Ensembl chr 2:127,582,652...127,630,817
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Nppa
natriuretic peptide type A
increases expression
EXP
Azacitidine results in increased expression of NPPA
CTD
PMID:15005238
NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
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Nppb
natriuretic peptide type B
increases expression
EXP
Azacitidine results in increased expression of NPPB
CTD
PMID:15005238
NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
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Nqo1
NAD(P)H dehydrogenase, quinone 1
multiple interactions
EXP
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]
CTD
PMID:17682057
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
multiple interactions
ISO
[metacept-1 co-treated with Azacitidine] results in increased expression of NR4A1
CTD
PMID:19148494
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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Nrip1
nuclear receptor interacting protein 1
decreases expression
ISO
Azacitidine results in decreased expression of NRIP1 mRNA
CTD
PMID:20823114
NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715
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Nrn1
neuritin 1
decreases expression
ISO
Azacitidine results in decreased expression of NRN1 mRNA
CTD
PMID:19194470
NCBI chr13:36,909,596...36,918,451
Ensembl chr13:36,909,335...36,919,105
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Nt5e
5' nucleotidase, ecto
increases expression
ISO
Azacitidine results in increased expression of NT5E mRNA
CTD
PMID:20823114
NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
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Nts
neurotensin
decreases expression
ISO
Azacitidine results in decreased expression of NTS mRNA
CTD
PMID:20823114
NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347
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Nusap1
nucleolar and spindle associated protein 1
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA
CTD
PMID:18720364
NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
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Nxt2
nuclear transport factor 2-like export factor 2
increases expression
ISO
Azacitidine results in increased expression of NXT2 mRNA
CTD
PMID:19194470
NCBI chr X:141,009,766...141,022,696
Ensembl chr X:141,009,766...141,022,688
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Ocln
occludin
increases expression
ISO
Azacitidine results in increased expression of OCLN mRNA
CTD
PMID:18661270
NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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Ogfrl1
opioid growth factor receptor-like 1
increases expression
ISO
Azacitidine results in increased expression of OGFRL1 mRNA
CTD
PMID:20823114
NCBI chr 1:23,405,505...23,422,282
Ensembl chr 1:23,405,505...23,436,853
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Ogg1
8-oxoguanine DNA-glycosylase 1
decreases expression decreases methylation
EXP
Azacitidine results in decreased expression of OGG1 protein Azacitidine results in decreased methylation of OGG1 promoter
CTD
PMID:22064374
NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
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Or8b8
olfactory receptor family 8 subfamily B member 8
increases expression
ISO
Azacitidine results in increased expression of OR8B8 mRNA
CTD
PMID:20823114
NCBI chr 9:37,801,863...37,809,634
Ensembl chr 9:37,808,020...37,814,815
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Oxr1
oxidation resistance 1
increases expression
ISO
Azacitidine results in increased expression of OXR1 mRNA
CTD
PMID:20823114
NCBI chr15:41,310,745...41,724,447
Ensembl chr15:41,310,878...41,724,444
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Oxtr
oxytocin receptor
decreases expression
ISO
Azacitidine results in decreased expression of OXTR mRNA
CTD
PMID:21245298
NCBI chr 6:112,450,646...112,467,800
Ensembl chr 6:112,450,644...112,466,904
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P4hb
prolyl 4-hydroxylase, beta polypeptide
increases expression
ISO
Azacitidine results in increased expression of P4HB protein Azacitidine results in increased expression of P4HB mRNA
CTD
PMID:17105402 PMID:20823114
NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
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Pak1
p21 (RAC1) activated kinase 1
increases expression
ISO
Azacitidine results in increased expression of PAK1 mRNA
CTD
PMID:20823114
NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588
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Pank3
pantothenate kinase 3
decreases expression
ISO
Azacitidine results in decreased expression of PANK3 mRNA
CTD
PMID:19194470
NCBI chr11:35,660,322...35,682,112
Ensembl chr11:35,660,311...35,682,112
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Parp1
poly (ADP-ribose) polymerase family, member 1
increases cleavage multiple interactions
EXP
Azacitidine results in increased cleavage of PARP1 protein Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]
CTD
PMID:32278510
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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Pax4
paired box 4
increases expression
ISO
Azacitidine results in increased expression of PAX4 mRNA
CTD
PMID:18949370
NCBI chr 6:28,442,333...28,449,339
Ensembl chr 6:28,442,333...28,449,352
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Pcdh18
protocadherin 18
decreases expression
ISO
Azacitidine results in decreased expression of PCDH18 mRNA
CTD
PMID:20823114
NCBI chr 3:49,697,745...49,711,723
Ensembl chr 3:49,697,745...49,711,774
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Pcdha1
protocadherin alpha 1
affects methylation
EXP
Azacitidine affects the methylation of PCDHA1 promoter
CTD
PMID:18204046
NCBI chr18:37,063,338...37,320,710
Ensembl chr18:37,063,237...37,320,714
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Pcdha10
protocadherin alpha 10
affects methylation
EXP
Azacitidine affects the methylation of PCDHA12 promoter
CTD
PMID:18204046
NCBI chr18:37,138,373...37,320,710
Ensembl chr18:37,138,256...37,320,710
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Pcdha11
protocadherin alpha 11
affects methylation
EXP
Azacitidine affects the methylation of PCDHA11 promoter
CTD
PMID:18204046
NCBI chr18:37,143,911...37,320,710
Ensembl chr18:37,143,765...37,320,710
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Pcdha2
protocadherin alpha 2
affects methylation
EXP
Azacitidine affects the methylation of PCDHA2 promoter
CTD
PMID:18204046
NCBI chr18:37,072,258...37,320,714
Ensembl chr18:37,072,258...37,320,710
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Pcdha3
protocadherin alpha 3
affects methylation
EXP
Azacitidine affects the methylation of PCDHA3 promoter
CTD
PMID:18204046
NCBI chr18:37,079,141...37,320,716
Ensembl chr18:37,079,158...37,320,710
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Pcdha4
protocadherin alpha 4
affects methylation
EXP
Azacitidine affects the methylation of PCDHA4 promoter
CTD
PMID:18204046
NCBI chr18:37,085,742...37,320,710
Ensembl chr18:37,085,701...37,320,714
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Pcdha5
protocadherin alpha 5
affects methylation
EXP
Azacitidine affects the methylation of PCDHA5 promoter
CTD
PMID:18204046
NCBI chr18:37,093,329...37,320,716
Ensembl chr18:37,093,493...37,320,710
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Pcdha6
protocadherin alpha 6
affects methylation
EXP
Azacitidine affects the methylation of PCDHA6 promoter
CTD
PMID:18204046
NCBI chr18:37,100,678...37,321,950
Ensembl chr18:37,100,684...37,320,710
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Pcdha7
protocadherin alpha 7
affects methylation
EXP
Azacitidine affects the methylation of PCDHA7 promoter
CTD
PMID:18204046
NCBI chr18:37,106,864...37,320,716
Ensembl chr18:37,106,855...37,320,710
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Pcdha8
protocadherin alpha 8
affects methylation
EXP
Azacitidine affects the methylation of PCDHA8 promoter; Azacitidine affects the methylation of PCDHA9 promoter
CTD
PMID:18204046
NCBI chr18:37,125,520...37,320,710
Ensembl chr18:37,125,424...37,320,710
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Pcdha9
protocadherin alpha 9
affects methylation
EXP
Azacitidine affects the methylation of PCDHA10 promoter
CTD
PMID:18204046
NCBI chr18:37,130,933...37,320,710
Ensembl chr18:37,130,933...37,320,710
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Pcdhb20
protocadherin beta 20
decreases expression
ISO
Azacitidine results in decreased expression of PCDHB14 mRNA
CTD
PMID:20823114
NCBI chr18:37,637,332...37,640,713
Ensembl chr18:37,637,317...37,640,875
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Pcdhb5
protocadherin beta 5
decreases expression
ISO
Azacitidine results in decreased expression of PCDHB4 mRNA
CTD
PMID:20823114
NCBI chr18:37,453,434...37,456,966
Ensembl chr18:37,453,434...37,456,968
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Pcna
proliferating cell nuclear antigen
decreases expression multiple interactions
ISO
Azacitidine results in decreased expression of PCNA protein [Cisplatin co-treated with Azacitidine] results in decreased expression of PCNA protein
CTD
PMID:19723570
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
increases expression
ISO
Azacitidine results in increased expression of PDK1 mRNA
CTD
PMID:20823114
NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
decreases methylation increases expression
ISO
Azacitidine results in decreased methylation of PDK4 promoter Azacitidine results in increased expression of PDK4 protein
CTD
PMID:28003426
NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
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Pecam1
platelet/endothelial cell adhesion molecule 1
increases expression
ISO
Azacitidine results in increased expression of PECAM1 mRNA
CTD
PMID:18037191
NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
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Pfn1
profilin 1
increases expression
ISO
Azacitidine results in increased expression of PFN1 mRNA
CTD
PMID:20823114
NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470
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Phactr2
phosphatase and actin regulator 2
increases expression
ISO
Azacitidine results in increased expression of PHACTR2 mRNA
CTD
PMID:20823114
NCBI chr10:13,083,461...13,350,266
Ensembl chr10:13,083,461...13,350,156
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Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
decreases expression
ISO
Azacitidine results in decreased expression of PIP5K1A mRNA
CTD
PMID:19194470
NCBI chr 3:94,965,841...95,014,241
Ensembl chr 3:94,965,841...95,014,241
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Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
decreases expression
ISO
Azacitidine results in decreased expression of PITPNC1 mRNA
CTD
PMID:20823114
NCBI chr11:107,098,718...107,361,546
Ensembl chr11:107,098,718...107,361,525
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Pitx3
paired-like homeodomain transcription factor 3
increases expression
ISO
Azacitidine results in increased expression of PITX3 mRNA
CTD
PMID:27415467
NCBI chr19:46,123,720...46,136,764
Ensembl chr19:46,124,124...46,136,765
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Pja1
praja ring finger ubiquitin ligase 1
increases expression
ISO
Azacitidine results in increased expression of PJA1 mRNA
CTD
PMID:19194470
NCBI chr X:98,509,344...98,514,874
Ensembl chr X:98,509,340...98,514,879
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Pkd2l1
polycystic kidney disease 2-like 1
increases expression
ISO
Azacitidine results in increased expression of PKD2L1 mRNA
CTD
PMID:20823114
NCBI chr19:44,136,076...44,235,355
Ensembl chr19:44,136,076...44,180,881
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Pkm
pyruvate kinase, muscle
increases expression
ISO
Azacitidine results in increased expression of PKM mRNA
CTD
PMID:20823114
NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
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Plcb1
phospholipase C, beta 1
decreases methylation increases expression increases response to substance decreases response to substance
ISO
Azacitidine results in decreased methylation of PLCB1 promoter Azacitidine results in increased expression of PLCB1 mRNA; Azacitidine results in increased expression of PLCB1 protein PLCB1 mRNA results in increased susceptibility to Azacitidine; PLCB1 protein results in increased susceptibility to Azacitidine PLCB1 promoter modified form results in decreased susceptibility to Azacitidine
CTD
PMID:19805378
NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178
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Plpp1
phospholipid phosphatase 1
increases expression
ISO
Azacitidine results in increased expression of PLPP1 mRNA
CTD
PMID:19194470
NCBI chr13:112,937,311...113,004,428
Ensembl chr13:112,937,326...113,004,428
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Pls3
plastin 3 (T-isoform)
decreases expression
ISO
Azacitidine results in decreased expression of PLS3 mRNA
CTD
PMID:20823114
NCBI chr X:74,829,259...74,918,788
Ensembl chr X:74,829,260...74,918,788
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Pml
promyelocytic leukemia
increases expression
ISO
Azacitidine results in increased expression of PML mRNA
CTD
PMID:19194470
NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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Pparg
peroxisome proliferator activated receptor gamma
decreases methylation increases expression
EXP
Azacitidine results in decreased methylation of PPARG promoter Azacitidine results in increased expression of PPARG mRNA
CTD
PMID:19589179
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
multiple interactions decreases methylation increases expression
ISO
Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter] Azacitidine results in decreased methylation of PPP2CA promoter Azacitidine results in increased expression of PPP2CA mRNA
CTD
PMID:19155497
NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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Prdx4
peroxiredoxin 4
decreases expression
ISO
Azacitidine results in decreased expression of PRDX4 protein
CTD
PMID:17105402
NCBI chr X:154,106,914...154,125,268
Ensembl chr X:154,106,914...154,123,750
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Prf1
perforin 1 (pore forming protein)
multiple interactions
ISO
Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein]
CTD
PMID:19394699
NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
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Prl
prolactin
multiple interactions
ISO
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein
CTD
PMID:20823114
NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
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Prom1
prominin 1
increases expression
ISO
Azacitidine results in increased expression of PROM1 mRNA
CTD
PMID:18037191
NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374
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Prss12
serine protease 12 neurotrypsin (motopsin)
decreases expression
ISO
Azacitidine results in decreased expression of PRSS12 mRNA
CTD
PMID:20823114
NCBI chr 3:123,240,562...123,300,251
Ensembl chr 3:123,240,562...123,300,246
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Psen1
presenilin 1
decreases methylation multiple interactions
EXP
Azacitidine results in decreased methylation of PSEN1 promoter Betaine inhibits the reaction [Azacitidine results in decreased methylation of PSEN1 promoter]
CTD
PMID:19635394
NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
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Pten
phosphatase and tensin homolog
multiple interactions
ISO
Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]
CTD
PMID:22841775
NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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Pthlh
parathyroid hormone-like peptide
decreases expression
ISO
Azacitidine results in decreased expression of PTHLH mRNA
CTD
PMID:20823114
NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681
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Ptpa
protein phosphatase 2 protein activator
increases expression
ISO
Azacitidine results in increased expression of PTPA mRNA
CTD
PMID:20823114
NCBI chr 2:30,306,062...30,337,819
Ensembl chr 2:30,306,051...30,337,818
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Ptprc
protein tyrosine phosphatase receptor type C
increases expression
ISO
Azacitidine results in increased expression of PTPRC mRNA
CTD
PMID:19194470
NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
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Ptpro
protein tyrosine phosphatase receptor type O
increases expression
ISO
Azacitidine results in increased expression of PTPRO mRNA
CTD
PMID:14508512
NCBI chr 6:137,229,189...137,440,251
Ensembl chr 6:137,229,317...137,440,231
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Rab13
RAB13, member RAS oncogene family
decreases methylation
ISO
Azacitidine results in decreased methylation of RAB13 promoter
CTD
PMID:19194470
NCBI chr 3:90,121,022...90,133,694
Ensembl chr 3:90,121,002...90,133,692
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Rab1b
RAB1B, member RAS oncogene family
increases expression
ISO
Azacitidine results in increased expression of RAB1B mRNA
CTD
PMID:20823114
NCBI chr19:5,149,235...5,157,024
Ensembl chr19:5,149,233...5,157,100
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Racgap1
Rac GTPase-activating protein 1
increases expression
ISO
Azacitidine results in increased expression of RACGAP1 mRNA
CTD
PMID:20823114
NCBI chr15:99,518,377...99,549,504
Ensembl chr15:99,518,377...99,549,537
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Ranbp2
RAN binding protein 2
increases expression
ISO
Azacitidine results in increased expression of RANBP2 mRNA
CTD
PMID:19194470
NCBI chr10:58,282,674...58,329,977
Ensembl chr10:58,282,742...58,330,178
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Rasa3
RAS p21 protein activator 3
increases expression
ISO
Azacitidine results in increased expression of RASA3 mRNA
CTD
PMID:20823114
NCBI chr 8:13,617,218...13,727,590
Ensembl chr 8:13,616,948...13,727,603
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Rcn1
reticulocalbin 1
decreases expression
ISO
Azacitidine results in decreased expression of RCN1 mRNA
CTD
PMID:20823114
NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664
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Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
affects localization decreases expression
ISO
Azacitidine affects the localization of RELA protein 5-azacytidine decreases expression of RELA protein in lung cancer cells
CTD RGD
PMID:18443271 PMID:24356455
RGD:153344603
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Ret
ret proto-oncogene
decreases expression
ISO
Azacitidine results in decreased expression of RET mRNA
CTD
PMID:20823114
NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
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Rfc3
replication factor C (activator 1) 3
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA
CTD
PMID:18720364
NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
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Rhob
ras homolog family member B
multiple interactions
ISO
[trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein; Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA]
CTD
PMID:18047684
NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009
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Rin1
Ras and Rab interactor 1
increases expression
ISO
Azacitidine results in increased expression of RIN1 mRNA
CTD
PMID:20823114
NCBI chr19:5,100,035...5,107,100
Ensembl chr19:5,100,509...5,107,099
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Rpp21
ribonuclease P 21 subunit
increases expression
ISO
Azacitidine results in increased expression of RPP21 mRNA
CTD
PMID:20823114
NCBI chr17:36,566,565...36,568,738
Ensembl chr17:36,566,537...36,568,961
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Rps6
ribosomal protein S6
decreases phosphorylation
ISO
Azacitidine results in decreased phosphorylation of RPS6 protein
CTD
PMID:21245298
NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
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Rpsa
ribosomal protein SA
decreases expression
ISO
Azacitidine results in decreased expression of RPSA mRNA
CTD
PMID:20823114
NCBI chr 9:119,956,832...119,961,435
Ensembl chr 9:119,956,755...119,961,435
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Rrm2
ribonucleotide reductase M2
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA
CTD
PMID:18720364
NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
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Rrm2b
ribonucleotide reductase M2 B (TP53 inducible)
increases expression
ISO
Azacitidine results in increased expression of RRM2B mRNA
CTD
PMID:19010910
NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562
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Runx1
runt related transcription factor 1
multiple interactions
ISO
Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter]
CTD
PMID:18945643
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
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Runx3
runt related transcription factor 3
affects methylation
ISO
Azacitidine affects the methylation of RUNX3 gene
CTD
PMID:18058463
NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
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S100a14
S100 calcium binding protein A14
decreases expression
ISO
Azacitidine results in decreased expression of S100A14 mRNA
CTD
PMID:20823114
NCBI chr 3:90,434,156...90,436,144
Ensembl chr 3:90,434,163...90,436,144
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S100a9
S100 calcium binding protein A9 (calgranulin B)
increases expression
ISO
Azacitidine results in increased expression of S100A9 mRNA
CTD
PMID:19194470
NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
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Sall4
spalt like transcription factor 4
affects methylation
ISO
Azacitidine affects the methylation of SALL4 promoter
CTD
PMID:17546590
NCBI chr 2:168,590,252...168,609,121
Ensembl chr 2:168,590,252...168,609,863
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Scamp4
secretory carrier membrane protein 4
increases expression
ISO
Azacitidine results in increased expression of SCAMP4 mRNA
CTD
PMID:20823114
NCBI chr10:80,438,716...80,451,617
Ensembl chr10:80,438,706...80,451,617
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Sdcbp
syndecan binding protein
decreases expression
ISO
Azacitidine results in decreased expression of SDCBP mRNA
CTD
PMID:20823114
NCBI chr 4:6,365,713...6,396,120
Ensembl chr 4:6,365,650...6,408,423
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Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
increases expression
ISO
Azacitidine results in increased expression of SEMA3A mRNA
CTD
PMID:20823114
NCBI chr 5:13,174,789...13,653,453
Ensembl chr 5:13,175,381...13,652,533
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Sema6c
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
increases expression
ISO
Azacitidine results in increased expression of SEMA6C mRNA
CTD
PMID:20823114
NCBI chr 3:95,067,731...95,081,361
Ensembl chr 3:95,067,768...95,081,335
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Senp3
SUMO/sentrin specific peptidase 3
increases expression
ISO
Azacitidine results in increased expression of SENP3 mRNA
CTD
PMID:20823114
NCBI chr11:69,563,936...69,572,910
Ensembl chr11:69,563,941...69,572,910
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Sirpb1a
signal-regulatory protein beta 1A
decreases expression
ISO
Azacitidine results in decreased expression of SIRPB1 mRNA
CTD
PMID:20823114
NCBI chr 3:15,436,887...15,491,487
Ensembl chr 3:15,436,713...15,491,580
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Six2
sine oculis-related homeobox 2
multiple interactions decreases expression
ISO
Cisplatin affects the reaction [Azacitidine results in decreased expression of SIX2 mRNA]
CTD
PMID:36336710
NCBI chr17:85,970,276...85,995,682
Ensembl chr17:85,991,705...85,995,702
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Slbp
stem-loop binding protein
multiple interactions
ISO
Azacitidine inhibits the reaction [sodium arsenite results in decreased expression of SLBP mRNA]
CTD
PMID:25266719
NCBI chr 5:33,797,399...33,809,918
Ensembl chr 5:33,792,296...33,809,918
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Slc28a1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
increases response to substance increases uptake multiple interactions
ISO
SLC28A1 protein results in increased susceptibility to Azacitidine SLC28A1 protein results in increased uptake of Azacitidine [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Sodium affects the reaction [SLC28A1 protein results in increased uptake of Azacitidine]
CTD
PMID:19139132
NCBI chr 7:80,763,017...80,820,164
Ensembl chr 7:80,764,547...80,820,164
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Slc29a2
solute carrier family 29 (nucleoside transporters), member 2
decreases expression
ISO
Azacitidine results in decreased expression of SLC29A2 mRNA
CTD
PMID:19194470
NCBI chr19:5,069,085...5,082,000
Ensembl chr19:5,073,888...5,082,000
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Slc5a5
solute carrier family 5 (sodium iodide symporter), member 5
multiple interactions increases expression
ISO
[Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA Azacitidine results in increased expression of SLC5A5 mRNA
CTD
PMID:16954431 PMID:17164311
NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
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Snu13
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
increases expression
ISO
Azacitidine results in increased expression of SNU13 mRNA
CTD
PMID:20823114
NCBI chr15:81,925,546...81,931,799
Ensembl chr15:81,924,726...81,931,799
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Socs3
suppressor of cytokine signaling 3
affects expression
ISO
Azacitidine affects the expression of SOCS3 protein
CTD
PMID:18443271
NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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Sox13
SRY (sex determining region Y)-box 13
decreases expression
ISO
Azacitidine results in decreased expression of SOX13 mRNA
CTD
PMID:20823114
NCBI chr 1:133,310,038...133,352,159
Ensembl chr 1:133,310,041...133,352,115
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Sox2
SRY (sex determining region Y)-box 2
increases expression
ISO
Azacitidine results in increased expression of SOX2 mRNA
CTD
PMID:27415467
NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610
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Sox8
SRY (sex determining region Y)-box 8
decreases expression
EXP
Azacitidine results in decreased expression of SOX8 mRNA
CTD
PMID:18033690
NCBI chr17:25,784,865...25,789,666
Ensembl chr17:25,784,634...25,789,726
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Sox9
SRY (sex determining region Y)-box 9
affects expression
EXP
Azacitidine affects the expression of SOX9 mRNA
CTD
PMID:18033690
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
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Sp1
trans-acting transcription factor 1
multiple interactions decreases expression
ISO EXP
Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter] Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter] Azacitidine results in decreased expression of SP1 mRNA
CTD
PMID:17198683 PMID:18945643 PMID:20823114
NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
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Sp7
Sp7 transcription factor 7
increases expression
EXP
Azacitidine results in increased expression of SP7 mRNA
CTD
PMID:17085970
NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
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Spag5
sperm associated antigen 5
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA
CTD
PMID:18720364
NCBI chr11:78,192,412...78,213,283
Ensembl chr11:78,192,355...78,213,283
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Srpx
sushi-repeat-containing protein
decreases expression
ISO
Azacitidine results in decreased expression of SRPX mRNA
CTD
PMID:19194470
NCBI chr X:9,904,216...9,983,879
Ensembl chr X:9,904,216...9,983,948
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Srsf7
serine and arginine-rich splicing factor 7
decreases expression
ISO
Azacitidine results in decreased expression of SRSF7 mRNA
CTD
PMID:20823114
NCBI chr17:80,507,509...80,514,734
Ensembl chr17:80,507,509...80,514,736
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Ssx2ip
SSX family member 2 interacting protein
increases expression
ISO
Azacitidine results in increased expression of SSX2IP mRNA
CTD
PMID:20823114
NCBI chr 3:146,110,397...146,145,899
Ensembl chr 3:146,110,397...146,145,899
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
increases expression
ISO
Azacitidine results in increased expression of ST3GAL6 mRNA
CTD
PMID:19194470
NCBI chr16:58,290,105...58,344,614
Ensembl chr16:58,288,488...58,344,606
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St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
decreases expression
ISO
Azacitidine results in decreased expression of ST8SIA2 mRNA
CTD
PMID:20823114
NCBI chr 7:73,588,867...73,663,408
Ensembl chr 7:73,588,867...73,663,438
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Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein
CTD
PMID:18443271
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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Stc2
stanniocalcin 2
decreases expression
ISO
Azacitidine results in decreased expression of STC2 mRNA
CTD
PMID:19194470
NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074
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Stk38
serine/threonine kinase 38
decreases expression
ISO
Azacitidine results in decreased expression of STK38 mRNA
CTD
PMID:20823114
NCBI chr17:29,189,854...29,226,979
Ensembl chr17:29,189,854...29,226,969
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Sulf1
sulfatase 1
decreases expression
ISO
Azacitidine results in decreased expression of SULF1 mRNA
CTD
PMID:20823114
NCBI chr 1:12,762,421...12,946,090
Ensembl chr 1:12,762,501...12,931,416
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Sult1c2
sulfotransferase family, cytosolic, 1C, member 2
increases expression
ISO
Azacitidine results in increased expression of SULT1C2 mRNA
CTD
PMID:19194470
NCBI chr17:54,136,665...54,152,986
Ensembl chr17:54,136,665...54,153,367
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Tat
tyrosine aminotransferase
increases expression
ISO
Azacitidine results in increased expression of TAT mRNA
CTD
PMID:27590069
NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
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Tbc1d4
TBC1 domain family, member 4
decreases expression
ISO
Azacitidine results in decreased expression of TBC1D4 mRNA
CTD
PMID:19194470
NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627
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Tcea1
transcription elongation factor A (SII) 1
decreases expression
ISO
Azacitidine results in decreased expression of TCEA1 mRNA
CTD
PMID:20823114
NCBI chr 1:4,927,917...4,968,132
Ensembl chr 1:4,928,037...4,968,132
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Tecpr2
tectonin beta-propeller repeat containing 2
increases expression
ISO
Azacitidine results in increased expression of TECPR2 mRNA
CTD
PMID:19194470
NCBI chr12:110,855,681...110,938,828
Ensembl chr12:110,855,698...110,938,828
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Tek
TEK receptor tyrosine kinase
increases expression
ISO
Azacitidine results in increased expression of TEK mRNA
CTD
PMID:18037191
NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
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Tert
telomerase reverse transcriptase
decreases expression decreases activity decreases methylation multiple interactions
ISO
Azacitidine analog results in decreased expression of TERT mRNA; Azacitidine results in decreased expression of TERT mRNA Azacitidine results in decreased activity of TERT protein Azacitidine results in decreased methylation of TERT promoter E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]; MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
CTD
PMID:18045574 PMID:19451745
NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
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Tfe3
transcription factor E3
increases expression
ISO
Azacitidine results in increased expression of TFE3 mRNA
CTD
PMID:19194470
NCBI chr X:7,628,769...7,641,441
Ensembl chr X:7,628,799...7,641,441
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Tgfb1
transforming growth factor, beta 1
multiple interactions
EXP ISO
[Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]; Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]
CTD
PMID:18493985 PMID:22841775
NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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Thumpd1
THUMP domain containing 1
increases expression
ISO
Azacitidine results in increased expression of THUMPD1 mRNA
CTD
PMID:19194470
NCBI chr 7:119,314,316...119,322,842
Ensembl chr 7:119,314,316...119,320,021
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Timp1
tissue inhibitor of metalloproteinase 1
increases expression
ISO
Azacitidine results in increased expression of TIMP1 mRNA
CTD
PMID:20823114
NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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Tjp1
tight junction protein 1
increases expression
ISO
Azacitidine results in increased expression of TJP1 mRNA
CTD
PMID:18661270
NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
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Tmed3
transmembrane p24 trafficking protein 3
increases expression
ISO
Azacitidine results in increased expression of TMED3 mRNA
CTD
PMID:20823114
NCBI chr 9:89,581,256...89,587,096
Ensembl chr 9:89,581,259...89,587,121
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Tmpo
thymopoietin
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA
CTD
PMID:18720364
NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177
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Tnc
tenascin C
decreases expression
ISO
Azacitidine results in decreased expression of TNC mRNA
CTD
PMID:20823114
NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
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Tnf
tumor necrosis factor
increases expression increases response to substance
ISO EXP
Azacitidine results in increased expression of TNF mRNA Azacitidine results in increased susceptibility to TNF protein
CTD
PMID:17156202 PMID:18829727
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfsf10
tumor necrosis factor (ligand) superfamily, member 10
increases response to substance
ISO EXP
Azacitidine results in increased susceptibility to TNFSF10 protein
CTD
PMID:18829727
NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
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Tnni3
troponin I, cardiac 3
increases expression
ISO
Azacitidine results in increased expression of TNNI3 protein
CTD
PMID:17105402
NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228
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Tnnt2
troponin T2, cardiac
increases expression
ISO
Azacitidine results in increased expression of TNNT2 protein
CTD
PMID:22496879
NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998
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Top2a
topoisomerase (DNA) II alpha
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA; [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA
CTD
PMID:18348204 PMID:18720364
NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
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Tpd52
tumor protein D52
increases expression
ISO
Azacitidine results in increased expression of TPD52 mRNA
CTD
PMID:27415467
NCBI chr 3:8,991,590...9,069,824
Ensembl chr 3:8,990,653...9,069,783
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Tpm2
tropomyosin 2, beta
increases expression
ISO
Azacitidine results in increased expression of TPM2 mRNA
CTD
PMID:20823114
NCBI chr 4:43,513,726...43,523,583
Ensembl chr 4:43,514,711...43,523,765
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Tpo
thyroid peroxidase
increases expression
ISO
Azacitidine results in increased expression of TPO mRNA
CTD
PMID:17679169
NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623
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Tpsg1
tryptase gamma 1
decreases expression
ISO
Azacitidine results in decreased expression of TPSG1 mRNA
CTD
PMID:20823114
NCBI chr17:25,588,169...25,593,416
Ensembl chr17:25,588,235...25,593,417
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Trh
thyrotropin releasing hormone
decreases expression
ISO
Azacitidine results in decreased expression of TRH mRNA
CTD
PMID:19194470
NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631
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Trib1
tribbles pseudokinase 1
decreases expression
ISO
Azacitidine results in decreased expression of TRIB1 mRNA
CTD
PMID:19194470
NCBI chr15:59,520,503...59,528,948
Ensembl chr15:59,520,199...59,528,948
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Trim8
tripartite motif-containing 8
increases expression
ISO
Azacitidine results in increased expression of TRIM8 mRNA
CTD
PMID:19194470
NCBI chr19:46,490,087...46,504,894
Ensembl chr19:46,490,141...46,505,287
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Trp53
transformation related protein 53
affects activity
ISO
Azacitidine affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Trp73
transformation related protein 73
multiple interactions
ISO
TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]
CTD
PMID:21245298
NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
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Tsc1
TSC complex subunit 1
multiple interactions
ISO
[Azacitidine affects the methylation of TSC1 promoter] which affects the expression of TSC1 mRNA
CTD
PMID:18538015
NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
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Tsc2
TSC complex subunit 2
decreases methylation increases expression multiple interactions
ISO
Azacitidine results in decreased methylation of TSC2 promoter Azacitidine results in increased expression of TSC2 mRNA [Azacitidine affects the methylation of TSC2 promoter] which affects the expression of TSC2 mRNA
CTD
PMID:18538015 PMID:19250671
NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
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Tshr
thyroid stimulating hormone receptor
increases expression
ISO
Azacitidine results in increased expression of TSHR mRNA
CTD
PMID:17679169
NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
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Tspan32
tetraspanin 32
decreases expression
ISO
Azacitidine results in decreased expression of TSPAN32 mRNA
CTD
PMID:19194470
NCBI chr 7:142,558,644...142,573,223
Ensembl chr 7:142,558,783...142,573,381
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Ttk
Ttk protein kinase
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA
CTD
PMID:18720364
NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442
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Ube2c
ubiquitin-conjugating enzyme E2C
multiple interactions
ISO
[Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA
CTD
PMID:18720364
NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
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Uhmk1
U2AF homology motif (UHM) kinase 1
increases expression
ISO
Azacitidine results in increased expression of UHMK1 mRNA
CTD
PMID:20823114
NCBI chr 1:170,020,989...170,043,466
Ensembl chr 1:170,020,989...170,042,966
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Ush2a
usherin
increases expression
ISO
Azacitidine results in increased expression of USH2A mRNA
CTD
PMID:20823114
NCBI chr 1:187,995,035...188,697,694
Ensembl chr 1:187,994,220...188,697,238
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Ushbp1
USH1 protein network component harmonin binding protein 1
decreases expression
ISO
Azacitidine results in decreased expression of USHBP1 mRNA
CTD
PMID:20823114
NCBI chr 8:71,836,918...71,848,480
Ensembl chr 8:71,836,916...71,848,446
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Vim
vimentin
decreases expression multiple interactions increases expression
ISO
Azacitidine results in decreased expression of VIM protein [Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein Azacitidine results in increased expression of VIM mRNA; Azacitidine results in increased expression of VIM protein
CTD
PMID:17105402 PMID:20823114
NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
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Wdr47
WD repeat domain 47
decreases expression
ISO
Azacitidine results in decreased expression of WDR47 mRNA
CTD
PMID:19194470
NCBI chr 3:108,498,302...108,553,035
Ensembl chr 3:108,498,595...108,553,035
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Wnt10b
wingless-type MMTV integration site family, member 10B
increases expression
ISO
Azacitidine results in increased expression of WNT10B mRNA
CTD
PMID:27415467
NCBI chr15:98,668,593...98,676,093
Ensembl chr15:98,668,593...98,676,031
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Wnt5a
wingless-type MMTV integration site family, member 5A
increases expression
ISO
Azacitidine results in increased expression of WNT5A mRNA
CTD
PMID:20823114
NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405
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Wwtr1
WW domain containing transcription regulator 1
increases expression
ISO
Azacitidine results in increased expression of WWTR1 mRNA
CTD
PMID:20823114
NCBI chr 3:57,363,065...57,483,331
Ensembl chr 3:57,363,070...57,483,331
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Xaf1
XIAP associated factor 1
decreases methylation decreases expression increases expression
ISO
Azacitidine results in decreased methylation of XAF1 promoter Azacitidine results in decreased expression of XAF1 mRNA alternative form Azacitidine results in increased expression of XAF1 mRNA; Azacitidine results in increased expression of XAF1 protein
CTD
PMID:19077051 PMID:19549372
NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559
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Zfp189
zinc finger protein 189
decreases expression
ISO
Azacitidine results in decreased expression of ZNF189 mRNA
CTD
PMID:20823114
NCBI chr 4:49,521,176...49,531,558
Ensembl chr 4:49,521,176...49,531,517
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Zfp64
zinc finger protein 64
affects methylation
ISO
Azacitidine affects the methylation of ZFP64 promoter
CTD
PMID:17546590
NCBI chr 2:168,735,251...168,797,507
Ensembl chr 2:168,735,251...168,797,507
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Zp3
zona pellucida glycoprotein 3
increases expression
ISO
Azacitidine results in increased expression of ZP3 mRNA
CTD
PMID:20823114
NCBI chr 5:136,008,959...136,017,478
Ensembl chr 5:136,008,953...136,017,478
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