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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2',3'-dideoxyribonucleoside
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Accession:CHEBI:47945 term browser browse the term
Synonyms:related_synonym: 2',3'-dideoxyribonucleosides


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2',3'-dideoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]; Dideoxyadenosine inhibits the reaction [Taurolithocholic Acid affects the localization of ABCC2 protein]; Dideoxyadenosine inhibits the reaction [Taurolithocholic Acid results in decreased activity of ABCC2 protein] CTD PMID:25813982 PMID:31300867 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Egf epidermal growth factor multiple interactions EXP Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein] CTD PMID:25813982 NCBI chr 2:68,820,616...68,895,537 JBrowse link
didanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Didanosine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Il24 interleukin 24 decreases expression ISO Didanosine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression
multiple interactions
ISO Didanosine results in decreased expression of COX2 mRNA
tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA]
CTD PMID:16940060 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Didanosine CTD PMID:19164483 NCBI chr20:30,289,527...30,327,343
Ensembl chr20:30,287,424...30,327,361
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Didanosine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
zalcitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation EXP Zalcitabine affects the phosphorylation of AKT1 protein CTD PMID:19781600 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin affects binding ISO Zalcitabine binds to ALB protein CTD PMID:15814459 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ano3 anoctamin 3 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ANO3 mRNA CTD PMID:18606552 NCBI chr 3:101,843,516...102,203,368
Ensembl chr 3:101,840,630...102,151,489
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Zalcitabine CTD PMID:17259346 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ARNT2 mRNA CTD PMID:18606552 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ATP2B4 mRNA CTD PMID:18606552 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Bptf bromodomain PHD finger transcription factor multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of BPTF mRNA CTD PMID:18606552 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Zalcitabine results in increased expression of CCL2 protein CTD PMID:17761732 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Zalcitabine results in increased expression of CXCL12 mRNA CTD PMID:17292584 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Zalcitabine results in increased expression of CXCR4 mRNA CTD PMID:17292584 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Dck deoxycytidine kinase affects response to substance ISO DCK protein affects the susceptibility to Zalcitabine CTD PMID:11952160 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Depdc1b DEP domain containing 1B multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of DEPDC1B mRNA CTD PMID:18606552 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of DLG5 mRNA CTD PMID:18606552 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ESRRG mRNA CTD PMID:18606552 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Fam81a family with sequence similarity 81, member A multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FAM81A mRNA CTD PMID:18606552 NCBI chr 8:76,521,662...76,579,387
Ensembl chr 8:76,521,657...76,579,387
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FPGT mRNA CTD PMID:18606552 NCBI chr 2:261,382,015...261,402,950
Ensembl chr 2:261,382,060...261,402,903
JBrowse link
G Gla galactosidase, alpha multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of GLA mRNA CTD PMID:18606552 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases response to substance
increases expression
multiple interactions
ISO
EXP
HTR2A gene results in increased susceptibility to Zalcitabine
Zalcitabine results in increased expression of HTR2A protein
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Zalcitabine
CTD PMID:17888573 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO Zalcitabine results in decreased expression of IL2RA mRNA; Zalcitabine results in decreased expression of IL2RA protein
Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA mRNA]; Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA protein]
CTD PMID:7606800 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of IRF7 mRNA CTD PMID:18606552 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Kif5a kinesin family member 5A multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA CTD PMID:18606552 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of LAMA5 mRNA CTD PMID:18606552 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Luzp2 leucine zipper protein 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of LUZP2 mRNA CTD PMID:18606552 NCBI chr 1:111,849,494...112,067,502
NCBI chr 1:113,419,707...113,531,330
Ensembl chr 1:111,849,998...113,527,735
JBrowse link
G Midn midnolin multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of MIDN mRNA CTD PMID:18606552 NCBI chr 7:12,414,303...12,426,712
Ensembl chr 7:12,414,733...12,424,367
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression
multiple interactions
ISO Zalcitabine results in decreased expression of COX1 protein
Uridine inhibits the reaction [Zalcitabine results in decreased expression of COX1 protein]
CTD PMID:17187420 PMID:18823003 PMID:20032772 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP Zalcitabine results in decreased expression of COX2 mRNA CTD PMID:19781600 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Zalcitabine results in decreased expression of COX3 protein CTD PMID:17508937 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Zalcitabine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein] CTD PMID:17904600 NCBI chr  X:1,787,266...1,789,524
Ensembl chr  X:1,787,266...1,789,524
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NECAB1 mRNA CTD PMID:18606552 NCBI chr 5:28,507,596...28,737,556
Ensembl chr 5:28,504,558...28,737,719
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NKIRAS1 mRNA CTD PMID:18606552 NCBI chr15:8,179,090...8,188,656
Ensembl chr15:8,179,102...8,183,682
JBrowse link
G Notch1 notch receptor 1 increases mutagenesis ISO Zalcitabine results in increased mutagenesis of NOTCH1 gene CTD PMID:18798262 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Npy neuropeptide Y multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NPY mRNA CTD PMID:18606552 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NTRK2 mRNA alternative form CTD PMID:18606552 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Per2 period circadian regulator 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of PER2 mRNA CTD PMID:18606552 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Rab27b RAB27B, member RAS oncogene family multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RAB27B mRNA CTD PMID:18606552 NCBI chr18:68,486,006...68,644,595
Ensembl chr18:68,488,942...68,551,558
JBrowse link
G Reg3b regenerating family member 3 beta multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B mRNA; [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B protein CTD PMID:18606552 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G RGD1310429 similar to Protein Njmu-R1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RGD1310429 mRNA CTD PMID:18606552 NCBI chr10:67,738,131...67,751,049
Ensembl chr10:67,739,103...67,751,002
JBrowse link
G Robo2 roundabout guidance receptor 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ROBO2 mRNA CTD PMID:18606552 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Sanbr SANT and BTB domain regulator of CSR multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RGD1305110 mRNA CTD PMID:18606552 NCBI chr14:108,305,343...108,376,618
Ensembl chr14:108,305,418...108,372,157
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SCUBE1 mRNA CTD PMID:18606552 NCBI chr 7:124,501,988...124,620,755
Ensembl chr 7:124,501,988...124,620,703
JBrowse link
G Senp5 SUMO specific peptidase 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SENP5 mRNA CTD PMID:18606552 NCBI chr11:72,035,540...72,070,679
Ensembl chr11:72,892,448...72,915,230
Ensembl chr11:72,892,448...72,915,230
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions
increases uptake
EXP Zalcitabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]; Zalcitabine promotes the reaction [SLC28A1 protein results in increased export of Uridine]
SLC28A1 protein results in increased uptake of Zalcitabine
CTD PMID:8027026 PMID:8700147 PMID:8713072 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Zalcitabine CTD PMID:19164483 NCBI chr20:30,289,527...30,327,343
Ensembl chr20:30,287,424...30,327,361
JBrowse link
G Slc35g2 solute carrier family 35, member G2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SLC35G2 mRNA CTD PMID:18606552 NCBI chr 8:108,854,134...108,881,519
Ensembl chr 8:108,854,146...108,880,879
JBrowse link
G Slc4a8 solute carrier family 4 member 8 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SLC4A8 mRNA CTD PMID:18606552 NCBI chr 7:142,397,352...142,467,398
Ensembl chr 7:142,397,371...142,464,158
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ST8SIA3 mRNA CTD PMID:18606552 NCBI chr18:59,748,766...59,755,257
Ensembl chr18:59,748,444...59,755,226
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SV2B mRNA CTD PMID:18606552 NCBI chr 1:136,664,199...136,842,247
Ensembl chr 1:136,664,204...136,842,247
JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Zalcitabine affects the expression of TFAM protein CTD PMID:7849699 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO Zalcitabine results in decreased expression of TK1 mRNA; Zalcitabine results in decreased expression of TK1 protein CTD PMID:14659972 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tk2 thymidine kinase 2 decreases expression ISO Zalcitabine results in decreased expression of TK2 mRNA CTD PMID:14659972 NCBI chr19:917,203...939,236
Ensembl chr19:917,203...939,221
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance EXP TRPV4 protein results in increased susceptibility to Zalcitabine CTD PMID:18234883 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO Zalcitabine results in increased expression of TYMP protein CTD PMID:16457948 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of VGF mRNA CTD PMID:18606552 NCBI chr12:22,677,302...22,680,630
Ensembl chr12:22,677,607...22,680,630
JBrowse link
zidovudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 increases expression ISO Zidovudine results in increased expression of ABCA3 mRNA CTD PMID:24292225 NCBI chr10:13,723,365...13,780,558
Ensembl chr10:13,723,405...13,779,963
JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 decreases expression
increases expression
ISO Zidovudine results in decreased expression of ABCA7 mRNA
Zidovudine results in increased expression of ABCA7 mRNA
CTD PMID:24292225 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Zidovudine results in decreased expression of ABCB11 mRNA CTD PMID:27765674 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Zidovudine results in increased expression of ABCB1 mRNA; Zidovudine results in increased expression of ABCB1 protein CTD PMID:9148857 PMID:15456083 PMID:18310046 PMID:24292225 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Zidovudine results in increased expression of ABCB9 mRNA CTD PMID:24292225 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Zidovudine results in increased expression of ABCC1 mRNA CTD PMID:24292225 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO Zidovudine results in increased expression of ABCC10 mRNA CTD PMID:24292225 NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO
EXP
Zidovudine results in increased expression of ABCC3 mRNA
Zidovudine results in decreased expression of ABCC3 mRNA
CTD PMID:24292225 PMID:27765674 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects abundance
increases expression
increases export
ISO ABCC4 protein affects the abundance of Zidovudine
Zidovudine results in increased expression of ABCC4 mRNA
ABCC4 protein results in increased export of Zidovudine
CTD PMID:15456083 PMID:18364470 PMID:18535159 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases export
increases expression
ISO ABCC5 protein results in increased export of Zidovudine
Zidovudine results in increased expression of ABCC5 mRNA
CTD PMID:15456083 PMID:18535159 PMID:24292225 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO Zidovudine results in increased expression of ABCC6 mRNA CTD PMID:24292225 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 increases expression ISO Zidovudine results in increased expression of ABCD1 mRNA CTD PMID:24292225 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 increases expression ISO Zidovudine results in increased expression of ABCF2 mRNA CTD PMID:24292225 NCBI chr 4:7,122,850...7,135,607
Ensembl chr 4:7,122,890...7,135,669
JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 increases expression ISO Zidovudine results in increased expression of ABCF3 mRNA CTD PMID:24292225 NCBI chr11:84,026,206...84,037,938
Ensembl chr11:84,026,207...84,037,938
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
decreases expression
increases export
decreases export
ISO
EXP
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]
Zidovudine results in increased expression of ABCG2 protein
Zidovudine results in decreased expression of ABCG2 mRNA
Zidovudine results in increased expression of ABCG2 mRNA
CTD PMID:17437964 PMID:19056916 PMID:24292225 PMID:27765674 PMID:28705594 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression EXP Zidovudine results in decreased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression ISO Zidovudine affects the expression of ACACA mRNA CTD PMID:20032539 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acacb acetyl-CoA carboxylase beta affects expression ISO Zidovudine affects the expression of ACACB mRNA CTD PMID:20032539 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Ada adenosine deaminase increases expression ISO Zidovudine results in increased expression of ADA protein CTD PMID:2261134 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of ADIPOQ protein
Zidovudine results in decreased expression of ADIPOQ mRNA; Zidovudine results in decreased expression of ADIPOQ protein
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA
CTD PMID:15865214 PMID:16931933 PMID:17503663 PMID:17668557 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 multiple interactions
increases expression
EXP [Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA; Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA]
Zidovudine results in increased expression of AGPAT3 mRNA
CTD PMID:28619387 NCBI chr20:11,060,584...11,144,806
Ensembl chr20:11,114,164...11,144,806
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP Zidovudine results in increased phosphorylation of AKT1 protein CTD PMID:29594326 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin affects binding ISO Zidovudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression
multiple interactions
EXP Zidovudine results in decreased expression of APOA5 mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA]
CTD PMID:28619387 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Aprt adenine phosphoribosyl transferase increases mutagenesis ISO Zidovudine results in increased mutagenesis of APRT gene CTD PMID:10970446 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of AQP9 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA
CTD PMID:18313992 PMID:20370541 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:68,247,800...69,347,223
Ensembl chr10:68,248,655...68,517,564
JBrowse link
G Asl argininosuccinate lyase multiple interactions
increases activity
EXP [Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein; silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein]
Zidovudine results in increased activity of ASL protein
CTD PMID:28619387 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5C1 mRNA CTD PMID:18313992 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO Zidovudine results in decreased expression of ATP5F1D mRNA CTD PMID:16894629 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ATP5MC3 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5G3 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression ISO Zidovudine results in increased expression of ATP5ME mRNA CTD PMID:16894629 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J2 mRNA CTD PMID:18313992 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5mg ATP synthase membrane subunit g increases expression ISO Zidovudine results in increased expression of ATP5MG mRNA CTD PMID:16894629 NCBI chr 8:49,220,441...49,227,273
Ensembl chr 8:49,220,443...49,227,273
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Zidovudine results in increased expression of ATP5PB mRNA CTD PMID:16894629 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5H mRNA CTD PMID:18313992 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ATP5PF mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5O mRNA
Zidovudine results in increased expression of ATP5PO mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 decreases expression ISO Zidovudine results in decreased expression of ATP8B1 mRNA CTD PMID:16894629 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects response to substance
increases expression
multiple interactions
decreases expression
ISO
EXP
BCL2 protein affects the susceptibility to Zidovudine
Zidovudine results in increased expression of BCL2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA
Drugs, Chinese Herbal promotes the reaction [Zidovudine results in decreased expression of BCL2 mRNA]
CTD PMID:9850737 PMID:17696246 PMID:18313992 PMID:29594326 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Zidovudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of BST2 mRNA CTD PMID:20370541 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Zidovudine results in increased expression of BTG2 mRNA CTD PMID:23675285 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of C3AR1 mRNA
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA
CTD PMID:16931933 PMID:20370541 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Cars cysteinyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO [Acrolein co-treated with Zidovudine] results in increased cleavage of CASP3 protein; Drugs, Chinese Herbal promotes the reaction [Zidovudine results in increased expression of CASP3 mRNA]
Zidovudine results in increased cleavage of CASP3 protein
Zidovudine results in increased expression of CASP3 protein
Zidovudine results in increased activity of CASP3 protein
2,6-dimethyl-3,5-bis(2'-propoxyethoxycarbonyl)-4-(2''-difluoromethoxyphenyl)-1,4-dihydropyridine inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; glutapyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; tauropyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]
CTD PMID:16601281 PMID:17696246 PMID:17943461 PMID:18801031 PMID:27238871 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO Zidovudine results in increased cleavage of CASP8 protein
Acrolein promotes the reaction [Zidovudine results in increased cleavage of CASP8 protein]; Zidovudine promotes the reaction [Acrolein results in increased cleavage of CASP8 protein]
CTD PMID:27238871 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to Zidovudine CTD PMID:19398959 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Zidovudine results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNA2 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Zidovudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690 PMID:20370541 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNB1 mRNA CTD PMID:20370541 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA
Zidovudine results in increased expression of CCND1 mRNA
CTD PMID:15784690 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
Zidovudine results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of CCNE2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnl2 cyclin L2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNL2 mRNA CTD PMID:20370541 NCBI chr 5:173,256,301...173,268,279
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCR5 mRNA CTD PMID:20370541 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdc25a cell division cycle 25A multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDC25A mRNA CTD PMID:20370541 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CDCA8 mRNA CTD PMID:20370541 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDK1 mRNA CTD PMID:20370541 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDK4 mRNA CTD PMID:20370541 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CDK6 mRNA CTD PMID:20370541 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects expression
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA
Zidovudine affects the expression of CDKN1A protein
Zidovudine results in decreased expression of CDKN1A mRNA
CTD PMID:15784690 PMID:18389896 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects expression
increases expression
ISO Zidovudine affects the expression of CDKN2A protein
Zidovudine results in increased expression of CDKN2A mRNA; Zidovudine results in increased expression of CDKN2A protein
CTD PMID:16797627 PMID:18389896 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Zidovudine results in decreased expression of CEBPA protein CTD PMID:15722030 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation
decreases expression
ISO Zidovudine results in increased phosphorylation of CHEK1 protein
Zidovudine results in decreased expression of CHEK1 protein
CTD PMID:19541796 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression
increases phosphorylation
ISO Zidovudine results in decreased expression of CHEK2 protein
Zidovudine results in increased phosphorylation of CHEK2 protein
CTD PMID:19541796 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chn1 chimerin 1 decreases expression ISO Zidovudine results in decreased expression of CHN1 mRNA CTD PMID:16894629 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Clec2dl1 C-type lectin domain family 2 member D-like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CLEC2I mRNA CTD PMID:16931933 NCBI chr 4:162,391,309...162,402,569
Ensembl chr 4:162,281,574...162,402,635
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 decreases expression ISO Zidovudine results in decreased expression of COX11 mRNA CTD PMID:16894629 NCBI chr10:78,168,691...78,173,845
Ensembl chr10:78,111,050...78,174,584
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 decreases expression ISO Zidovudine results in decreased expression of COX15 mRNA CTD PMID:16894629 NCBI chr 1:263,494,850...263,511,510
Ensembl chr 1:263,494,852...263,511,505
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of COX5A protein
[Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA
Zidovudine results in decreased expression of COX5B protein
CTD PMID:7807166 PMID:18313992 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of COX6C protein
[Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression ISO Zidovudine results in decreased expression of COX7A1 protein CTD PMID:7807166 NCBI chr 1:91,070,593...91,096,190
Ensembl chr 1:91,071,493...91,074,294
Ensembl chr 1:91,071,493...91,074,294
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 increases expression ISO Zidovudine results in increased expression of COX7A2 mRNA CTD PMID:16894629 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B increases expression
decreases expression
ISO Zidovudine results in increased expression of COX7B mRNA
Zidovudine results in decreased expression of COX7B protein
CTD PMID:7807166 PMID:16894629 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of COX7C protein
[Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA
CTD PMID:7807166 PMID:18313992 NCBI chr 2:14,699,878...14,701,903
Ensembl chr 2:14,699,882...14,701,903
JBrowse link
G Cpne5 copine 5 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CPNE5 mRNA CTD PMID:20370541 NCBI chr20:6,419,033...6,500,843
Ensembl chr20:6,419,033...6,500,523
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA
Zidovudine results in increased expression of CPT1A mRNA
CTD PMID:14576092 PMID:18313992 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crat carnitine O-acetyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Cs citrate synthase affects expression
decreases expression
ISO Zidovudine affects the expression of CS mRNA
Zidovudine results in decreased expression of CS protein
CTD PMID:1892364 PMID:20032539 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of CSF2RA mRNA]; [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of IL3RA mRNA] CTD PMID:12084393 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha multiple interactions
decreases expression
ISO [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of CSF2RA mRNA] CTD PMID:12084393 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CSGALNACT1 mRNA CTD PMID:20370541 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Cul7 cullin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr 9:16,629,491...16,643,527
Ensembl chr 9:16,629,401...16,643,182
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions
decreases expression
ISO
EXP
[Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA
Zidovudine results in decreased expression of CYB5A mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA; Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA]
CTD PMID:18313992 PMID:28619387 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CYP1B1 mRNA CTD PMID:20370541 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions EXP [SOD2 co-treated with CYP3A4] affects the susceptibility to Zidovudine CTD PMID:19501153 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA
Zidovudine results in increased expression of DDIT3 mRNA
CTD PMID:15784690 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of DDR2 mRNA CTD PMID:20370541 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dmd dystrophin affects localization ISO Zidovudine affects the localization of DMD protein CTD PMID:17943461 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of DNA2 mRNA CTD PMID:20370541
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
affects localization
ISO
EXP
[DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of and affects the phosphorylation of DNM1L protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of DNM1L mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the localization of DNM1L protein
Zidovudine affects the localization of DNM1L protein
CTD PMID:28683400 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of DTX3L mRNA CTD PMID:20370541 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions
affects response to substance
ISO [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of and affects the phosphorylation of DNM1L protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of DNM1L mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 protein; [DTYMK protein affects the susceptibility to Zidovudine] which affects the localization of DNM1L protein; DTYMK gene mutant form results in increased phosphorylation of and results in increased susceptibility to Zidovudine CTD PMID:17375075 PMID:28683400 NCBI chr 9:100,921,565...100,930,399
Ensembl chr 9:100,921,565...100,930,399
JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:89,904,578...89,918,296
Ensembl chr10:89,904,560...89,918,427
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion
ISO coenzyme Q10 inhibits the reaction [Zidovudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Zidovudine co-treated with Arsenic Trioxide] results in increased expression of EGR1 mRNA CTD PMID:29910624 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ehf ets homologous factor multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of EHF mRNA CTD PMID:20370541 NCBI chr 3:93,176,257...93,216,484
Ensembl chr 3:93,178,163...93,216,495
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Zidovudine results in increased phosphorylation of EIF2S1 protein CTD PMID:27041070 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Epo erythropoietin increases expression
multiple interactions
ISO Zidovudine results in increased expression of EPO protein
EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]; EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]]; Zidovudine inhibits the reaction [EPO protein binds to EPOR protein]; Zidovudine promotes the reaction [Staphylococcal Protein A results in increased expression of EPO protein]
CTD PMID:1549625 PMID:1889487 PMID:3422548 PMID:7646543 PMID:9735323 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
ISO EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]]; Zidovudine inhibits the reaction [EPO protein binds to EPOR protein]
Zidovudine results in decreased expression of EPOR mRNA; Zidovudine results in decreased expression of EPOR protein
CTD PMID:1417927 PMID:7646543 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Epsti1 epithelial stromal interaction 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of EPSTI1 mRNA CTD PMID:20370541 NCBI chr15:60,084,966...60,190,360
Ensembl chr15:60,084,918...60,190,363
JBrowse link
G Esr1 estrogen receptor 1 affects localization EXP Zidovudine affects the localization of ESR1 protein CTD PMID:15531092 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Fabp4 fatty acid binding protein 4 affects expression ISO Zidovudine affects the expression of FABP4 mRNA CTD PMID:20032539 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Zidovudine results in increased expression of FAS protein CTD PMID:17943461 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of FASLG protein
Zidovudine results in increased expression of FASLG mRNA
Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]
[Acrolein co-treated with Zidovudine] results in increased expression of FASLG protein; Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Hydralazine inhibits the reaction [Zidovudine results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]; Zidovudine promotes the reaction [Acrolein results in increased expression of FASLG mRNA]; Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]
CTD PMID:17943461 PMID:27238871 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase affects expression
decreases expression
multiple interactions
ISO Zidovudine affects the expression of FASN mRNA
Zidovudine results in decreased expression of FASN protein
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA
CTD PMID:11741158 PMID:15722030 PMID:20032539 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of FCGR1A mRNA CTD PMID:20370541 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fgl2 fibrinogen-like 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of FGL2 mRNA CTD PMID:20370541 NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]] CTD PMID:7646543 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in decreased expression of FOXP3 mRNA CTD PMID:23962110 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC mRNA CTD PMID:16931933 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:112,173,907...112,226,886
Ensembl chr 3:112,173,907...112,226,023
JBrowse link
G Gars glycyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of GAS1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 PMID:20370541 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gata1 GATA binding protein 1 decreases activity
decreases expression
ISO Zidovudine results in decreased activity of GATA1 protein
Zidovudine results in decreased expression of GATA1 mRNA
CTD PMID:8599995 PMID:10651068 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gbp1 guanylate binding protein 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of GBP1 mRNA CTD PMID:20370541 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gbp4 guanylate binding protein 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of GBP4 mRNA CTD PMID:20370541 NCBI chr 2:248,249,232...248,263,104
Ensembl chr 2:248,249,468...248,263,168
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
EXP Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]; Silybin inhibits the reaction [Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]] CTD PMID:28619387 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grb7 growth factor receptor bound protein 7 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of GRB7 mRNA CTD PMID:20370541 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression ISO Zidovudine results in increased expression of GTF2H1 mRNA; Zidovudine results in increased expression of GTF2H1 protein CTD PMID:21192964 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gypa glycophorin A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased mutagenesis of GYPA gene CTD PMID:17358027 NCBI chr19:31,115,545...31,131,079 JBrowse link
G H4c3 H4 clustered histone 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of H4C3 mRNA CTD PMID:20370541 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) affects expression ISO Zidovudine affects the expression of H6PD mRNA CTD PMID:20032539 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 2:189,330,900...189,333,305
Ensembl chr 2:189,330,902...189,333,322
JBrowse link
G Hbb hemoglobin subunit beta decreases expression ISO Zidovudine results in decreased expression of HBB mRNA CTD PMID:10651068 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hdlbp high density lipoprotein binding protein decreases expression ISO Zidovudine results in decreased expression of HDLBP mRNA CTD PMID:16894629 NCBI chr 9:100,554,574...100,624,707
Ensembl chr 9:100,554,563...100,624,638
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of HERC6 mRNA CTD PMID:20370541 NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Zidovudine results in increased expression of HMOX1 mRNA CTD PMID:29594326 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO Zidovudine results in increased mutagenesis of HPRT1 exon CTD PMID:10526209 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene CTD PMID:9766437 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 affects expression ISO Zidovudine affects the expression of HSD11B1 mRNA CTD PMID:20032539 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B3 mRNA CTD PMID:18313992 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Zidovudine affects the expression of HSPD1 protein CTD PMID:27041070 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH2 mRNA CTD PMID:18313992 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH3A mRNA CTD PMID:18313992 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of IDH3G mRNA CTD PMID:18313992 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IFI27 mRNA CTD PMID:20370541 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifi35 interferon-induced protein 35 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IFI35 mRNA CTD PMID:20370541 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626
JBrowse link
G Ifi44l interferon-induced protein 44-like multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IFI44L mRNA CTD PMID:20370541 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IFIH1 mRNA CTD PMID:20370541 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IFIT2 mRNA CTD PMID:20370541 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifng interferon gamma affects expression
multiple interactions
ISO Zidovudine affects the expression of IFNG protein
[Arsenic co-treated with Zidovudine co-treated with IFNG protein] results in increased expression of IL2 mRNA
CTD PMID:9612607 PMID:23962110 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in decreased expression of IL10 mRNA; [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in decreased expression of IL10 protein CTD PMID:23962110 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Zidovudine results in increased expression of IL1A protein CTD PMID:7979221 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Zidovudine results in increased expression of IL1B mRNA; Zidovudine results in increased expression of IL1B protein CTD PMID:9184656 PMID:17668557 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in increased expression of IL2 mRNA; [Arsenic co-treated with Zidovudine co-treated with IFNG protein] results in increased expression of IL2 mRNA CTD PMID:23962110 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IL27RA mRNA CTD PMID:15784690 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha multiple interactions
decreases expression
ISO Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA mRNA]; Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA protein]
Zidovudine results in decreased expression of IL2RA mRNA; Zidovudine results in decreased expression of IL2RA protein
CTD PMID:7606800 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il3 interleukin 3 multiple interactions ISO [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of CSF2RA mRNA]; [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of IL3RA mRNA]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of EPOR mRNA]]; IL3 protein promotes the reaction [EPO protein inhibits the reaction [Zidovudine results in decreased expression of FOS mRNA]] CTD PMID:7646543 PMID:12084393 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il3ra interleukin 3 receptor subunit alpha multiple interactions
decreases expression
ISO [IL3 protein co-treated with CSF2 protein] inhibits the reaction [Zidovudine results in decreased expression of IL3RA mRNA] CTD PMID:12084393 NCBI chr12:18,534,762...18,542,508
Ensembl chr12:18,534,767...18,540,166
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Arsenic co-treated with Zidovudine co-treated with IFNA1 protein] results in decreased expression of IL4 mRNA CTD PMID:23962110 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression ISO Zidovudine results in increased expression of IL6 protein CTD PMID:17668557 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of INPP5E mRNA CTD PMID:18313992 NCBI chr 3:3,843,307...3,856,154
Ensembl chr 3:3,843,307...3,855,981
JBrowse link
G Irf2 interferon regulatory factor 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IRF2 mRNA CTD PMID:20370541 NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO IRF4 protein results in decreased susceptibility to [Zidovudine co-treated with IFNA1 protein] CTD PMID:17138822 NCBI chr17:34,886,746...34,905,191
Ensembl chr17:34,886,739...34,905,117
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of IRF7 mRNA CTD PMID:20370541 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of ISG15 mRNA CTD PMID:20370541 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of ITIH4 mRNA CTD PMID:20370541 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of JAK2 mRNA CTD PMID:20370541 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNA CTD PMID:15784690 NCBI chr 3:165,020,230...165,040,966
Ensembl chr 3:165,020,230...165,039,707
JBrowse link
G Kifc2 kinesin family member C2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA CTD PMID:16931933 NCBI chr 7:117,722,732...117,730,702
Ensembl chr 7:117,723,263...117,730,702
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KLF4 mRNA CTD PMID:15784690 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO Zidovudine results in increased mutagenesis of KRAS gene CTD PMID:18800350 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt7 keratin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNA CTD PMID:15784690 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Kynu kynureninase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KYNU mRNA CTD PMID:15784690 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of LAMB3 mRNA CTD PMID:15784690 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression EXP Zidovudine results in decreased expression of LAMP2 protein CTD PMID:29594326 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LAMP3 mRNA CTD PMID:20370541 NCBI chr11:84,930,965...85,000,694
Ensembl chr11:84,972,132...85,000,681
JBrowse link
G Lap3 leucine aminopeptidase 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LAP3 mRNA CTD PMID:20370541 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lep leptin decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of LEP protein
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LEP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA
CTD PMID:16931933 PMID:17668557 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of LGALS1 mRNA CTD PMID:20370541 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals9 galectin 9 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LGALS9 mRNA CTD PMID:20370541 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LILRB4 mRNA CTD PMID:20370541 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G Lipe lipase E, hormone sensitive type affects expression ISO Zidovudine affects the expression of LIPE mRNA CTD PMID:20032539 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial affects expression ISO Zidovudine affects the expression of LONP1 protein CTD PMID:27041070 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Lpl lipoprotein lipase decreases expression
multiple interactions
affects expression
ISO Zidovudine results in decreased expression of LPL mRNA
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LPL mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of LPL mRNA
Zidovudine affects the expression of LPL mRNA
CTD PMID:11741158 PMID:16894629 PMID:20032539 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LY6E mRNA CTD PMID:20370541 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Zidovudine results in increased phosphorylation of MAPK8 protein CTD PMID:27041070 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MARS1 mRNA CTD PMID:15784690 NCBI chr 7:70,585,011...70,602,425
Ensembl chr 7:70,585,013...70,602,310
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Zidovudine results in increased expression of MDM2 protein CTD PMID:16797627 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNA
Zidovudine results in decreased expression of ME1 mRNA
CTD PMID:11741158 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mff mitochondrial fission factor multiple interactions ISO [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of MFF protein CTD PMID:28683400 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN1 mRNA CTD PMID:18313992 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:43,249,369...44,024,278
Ensembl chr 7:44,009,069...44,024,456
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Zidovudine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 mRNA]; Zidovudine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]; Zidovudine inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP2 protein] CTD PMID:14662518 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Zidovudine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Zidovudine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Zidovudine inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein] CTD PMID:14662518 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression
increases expression
ISO Zidovudine affects the expression of MMUT mRNA mutant form; Zidovudine affects the expression of MMUT protein mutant form
Zidovudine results in increased expression of MMUT mRNA; Zidovudine results in increased expression of MMUT protein
CTD PMID:19199343 PMID:19427250 NCBI chr 9:23,323,934...23,352,144
Ensembl chr 9:23,323,936...23,352,668
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of MNDA mRNA CTD PMID:20370541 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of MOV10 mRNA CTD PMID:20370541 NCBI chr 2:207,277,088...207,301,245
Ensembl chr 2:207,278,161...207,300,854
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Zidovudine affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of MRAP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 increases expression ISO Zidovudine results in increased expression of ATP6 mRNA CTD PMID:16894629 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression
decreases expression
multiple interactions
ISO
EXP
Zidovudine results in increased expression of COX1 mRNA
Zidovudine results in decreased expression of COX1 protein
[Zidovudine co-treated with Lamivudine] results in decreased expression of COX1 mRNA; Uridine inhibits the reaction [Zidovudine results in decreased expression of COX1 protein]
CTD PMID:7528833 PMID:17526437 PMID:18163507 PMID:18313992 PMID:20032772 PMID:29594326 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression
multiple interactions
increases expression
ISO Zidovudine results in decreased expression of COX2 protein
[Zidovudine co-treated with Lamivudine] results in decreased expression of COX2 mRNA
Zidovudine results in increased expression of COX2 mRNA
CTD PMID:7807166 PMID:10912924 PMID:16894629 PMID:18313992 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III affects expression
multiple interactions
decreases expression
increases expression
ISO
EXP
Zidovudine affects the expression of COX3 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of COX3 mRNA
Zidovudine results in decreased expression of COX3 mRNA
Zidovudine results in increased expression of COX3 mRNA
CTD PMID:8828681 PMID:9799652 PMID:16894629 PMID:17526437 PMID:18313992 PMID:20032539 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b affects expression
decreases expression
increases expression
ISO
EXP
Zidovudine affects the expression of CYTB mRNA
Zidovudine results in decreased expression of CYTB mRNA
Zidovudine results in increased expression of CYTB mRNA
CTD PMID:1715447 PMID:7528833 PMID:20032539 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression ISO Zidovudine results in increased expression of ND1 mRNA CTD PMID:16894629 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ND2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ND2 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 increases expression
affects expression
ISO Zidovudine results in increased expression of ND4 mRNA
Zidovudine affects the expression of ND4 mRNA
CTD PMID:16894629 PMID:20032539 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ND5 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ND5 mRNA
CTD PMID:16894629 PMID:17526437 PMID:18313992 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of MT2A mRNA CTD PMID:20370541 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MTHFD2 mRNA CTD PMID:15784690 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation EXP Zidovudine results in increased phosphorylation of MTOR protein CTD PMID:29594326 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mvd mevalonate diphosphate decarboxylase multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of MVD mRNA CTD PMID:20370541 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of MX1 mRNA CTD PMID:20370541 NCBI chr11:37,891,150...37,916,775
Ensembl chr11:37,891,156...37,914,983
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Zidovudine results in increased expression of MYH7 mRNA; Zidovudine results in increased expression of MYH7 protein CTD PMID:9799652 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:89,149,314...89,152,511
Ensembl chr 4:89,149,317...89,151,184
JBrowse link
G Nat2 N-acetyltransferase 2 decreases expression
multiple interactions
EXP Zidovudine results in decreased expression of NAT2 mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA]
CTD PMID:28619387 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFA4 mRNA CTD PMID:18313992 NCBI chr 4:38,233,680...38,240,848
Ensembl chr 4:38,233,680...38,240,848
JBrowse link
G Ndufa6 NADH:ubiquinone oxidoreductase subunit A6 increases expression ISO Zidovudine results in increased expression of NDUFA6 mRNA CTD PMID:16894629 NCBI chr 7:123,583,062...123,586,919
Ensembl chr 7:123,583,062...123,586,919
JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 increases expression ISO Zidovudine results in increased expression of NDUFA9 mRNA CTD PMID:16894629 NCBI chr 4:159,371,263...159,399,636
Ensembl chr 4:159,371,259...159,399,634
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression
multiple interactions
ISO Zidovudine results in increased expression of NDUFAB1 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAB1 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAF1 mRNA CTD PMID:18313992 NCBI chr 3:111,458,227...111,469,239
Ensembl chr 3:111,458,572...111,469,518
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Zidovudine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein] CTD PMID:17904600 NCBI chr  X:1,787,266...1,789,524
Ensembl chr  X:1,787,266...1,789,524
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 increases expression
multiple interactions
ISO Zidovudine results in increased expression of NDUFB3 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB3 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 9:65,478,496...65,488,708
Ensembl chr 9:65,478,496...65,488,702
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 increases expression
multiple interactions
ISO Zidovudine results in increased expression of NDUFB5 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB5 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 2:119,139,717...119,153,753
Ensembl chr 2:119,139,717...119,153,753
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 increases expression ISO Zidovudine results in increased expression of NDUFB6 mRNA CTD PMID:16894629 NCBI chr 5:56,567,109...56,576,676
Ensembl chr 5:56,567,109...56,576,676
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFB9 mRNA CTD PMID:18313992 NCBI chr 7:98,813,062...98,819,408
Ensembl chr 7:98,813,040...98,819,452
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 increases expression
multiple interactions
ISO Zidovudine results in increased expression of NDUFC1 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of NDUFC1 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 2:140,460,749...140,464,588
Ensembl chr 2:140,462,900...140,464,607
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 increases expression
multiple interactions
ISO Zidovudine results in increased expression of NDUFS1 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of NDUFS1 mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Zidovudine results in decreased expression of NDUFS2 mRNA CTD PMID:16894629 NCBI chr13:89,606,848...89,623,506
Ensembl chr13:89,606,840...89,619,398
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 increases expression ISO Zidovudine results in increased expression of NDUFS5 mRNA CTD PMID:16894629 NCBI chr 5:141,390,577...141,405,507
Ensembl chr 5:141,390,580...141,405,453
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 increases expression ISO Zidovudine results in increased expression of NDUFS6 mRNA CTD PMID:16894629 NCBI chr 2:26,471,173...26,471,587
Ensembl chr 2:26,471,173...26,471,584
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression ISO Zidovudine results in decreased expression of NDUFV1 mRNA CTD PMID:16894629 NCBI chr 1:219,254,293...219,259,328
Ensembl chr 1:219,254,279...219,259,448
JBrowse link
G Nexn nexilin (F actin binding protein) multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of NEXN mRNA CTD PMID:20370541 NCBI chr 2:257,452,937...257,484,607
Ensembl chr 2:257,453,347...257,484,587
JBrowse link
G Nfe2 nuclear factor, erythroid 2 decreases activity
decreases expression
ISO Zidovudine results in decreased activity of NFE2 protein
Zidovudine results in decreased expression of NFE2 mRNA
CTD PMID:8599995 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression EXP Zidovudine results in increased expression of NFE2L2 protein CTD PMID:29594326 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NIBAN1 mRNA CTD PMID:15784690 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
ISO coenzyme Q10 inhibits the reaction [Zidovudine results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA
Zidovudine results in increased expression of NPPA mRNA
CTD PMID:10701688 PMID:11706060 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Zidovudine results in increased expression of NQO1 mRNA CTD PMID:29594326 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Zidovudine affects the expression of NR3C1 mRNA CTD PMID:20032539 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO Zidovudine results in increased expression of NRF1 mRNA CTD PMID:17926646 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Nt5c3a 5'-nucleotidase, cytosolic IIIA multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of NT5C3A mRNA CTD PMID:20370541 NCBI chr 4:87,238,325...87,281,234
Ensembl chr 4:87,237,949...87,281,157
JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of NUB1 mRNA CTD PMID:20370541 NCBI chr 4:6,950,870...6,981,400
Ensembl chr 4:6,951,478...6,978,073
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of NUF2 mRNA CTD PMID:20370541 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:122,643,952...122,741,322
Ensembl chr 4:122,644,135...122,741,110
JBrowse link
G Nxnl2 nucleoredoxin-like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NXNL2 mRNA CTD PMID:16931933 NCBI chr17:14,053,896...14,058,642
Ensembl chr17:14,053,896...14,058,642
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of OAS1 mRNA CTD PMID:20370541 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of OAS2 mRNA CTD PMID:20370541 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of OAS3 mRNA CTD PMID:20370541 NCBI chr12:41,313,081...41,368,217
Ensembl chr12:41,316,764...41,336,562
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of OAZ3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:195,675,925...195,678,859
Ensembl chr 2:195,676,048...195,678,848
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OGT mRNA CTD PMID:15784690 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPA1 mRNA
[DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 mRNA; [DTYMK protein affects the susceptibility to Zidovudine] which affects the expression of OPA1 protein
CTD PMID:18313992 PMID:28683400 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPRL1 mRNA CTD PMID:16931933 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of PARP9 mRNA CTD PMID:20370541 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
JBrowse link
G Pcbp4 poly(rC) binding protein 4 increases expression ISO Zidovudine results in increased expression of PCBP4 mRNA CTD PMID:23675285 NCBI chr 8:115,154,848...115,165,706
Ensembl chr 8:115,155,470...115,165,706
JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:14,952,213...15,334,745
Ensembl chr20:14,952,213...15,334,745
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PCK2 mRNA CTD PMID:15784690 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of PCNA mRNA CTD PMID:20370541 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Zidovudine results in decreased expression of PEBP1 mRNA CTD PMID:16894629 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of PF4 mRNA CTD PMID:20370541 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PFKFB3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pgap6 post-glycosylphosphatidylinositol attachment to proteins 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PGAP6 mRNA CTD PMID:16931933 NCBI chr10:15,484,952...15,495,380
Ensembl chr10:15,484,795...15,495,377
JBrowse link
G Pgr progesterone receptor multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of PGR mRNA CTD PMID:20370541 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:158,698,353...158,739,855
Ensembl chr  X:158,698,356...158,739,838
Ensembl chr  X:158,698,356...158,739,838
JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIDD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of PIK3AP1 mRNA CTD PMID:20370541 NCBI chr 1:260,527,344...260,679,132
Ensembl chr 1:260,527,781...260,638,915
JBrowse link
G Pirb paired Ig-like receptor B multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of LILRB3 mRNA CTD PMID:20370541 NCBI chr 1:64,074,097...64,081,568
Ensembl chr 1:64,074,231...64,081,438
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:52,037,693...52,116,277
Ensembl chr15:52,037,693...52,116,001
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of PKMYT1 mRNA CTD PMID:20370541 NCBI chr10:13,061,077...13,072,277
Ensembl chr10:13,061,170...13,073,283
JBrowse link
G Plscr1 phospholipid scramblase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of PLSCR1 mRNA CTD PMID:20370541 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase increases expression ISO Zidovudine results in increased expression of PNKP mRNA CTD PMID:23675285 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression
multiple interactions
EXP Zidovudine results in decreased expression of POR mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA]
CTD PMID:28619387 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PPN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:15,035,569...15,048,440
Ensembl chr  X:15,035,569...15,048,440
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Zidovudine results in decreased expression of PPARG mRNA; Zidovudine results in decreased expression of PPARG protein CTD PMID:15722030 PMID:17926646 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PRDM1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PSAT1 mRNA CTD PMID:15784690 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Zidovudine results in decreased expression of PTGS2 protein CTD PMID:18389896 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rab17 RAB17, member RAS oncogene family multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of RAB17 mRNA CTD PMID:20370541 NCBI chr 9:98,118,907...98,131,883
Ensembl chr 9:98,118,908...98,131,883
JBrowse link
G Rab3b RAB3B, member RAS oncogene family multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of RAB3B mRNA CTD PMID:20370541 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RABEPK mRNA CTD PMID:15784690 NCBI chr 3:13,845,352...13,865,843
Ensembl chr 3:13,845,361...13,865,843
JBrowse link
G Rassf7 Ras association domain family member 7 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of RASSF7 mRNA CTD PMID:20370541 NCBI chr 1:214,202,722...214,205,799
Ensembl chr 1:214,203,861...214,205,782
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNA CTD PMID:15784690 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNA CTD PMID:15784690 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO REL protein results in decreased susceptibility to [Zidovudine co-treated with IFNA1 protein] CTD PMID:17138822 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 2,6-dimethyl-3,5-bis(2'-propoxyethoxycarbonyl)-4-(2''-difluoromethoxyphenyl)-1,4-dihydropyridine inhibits the reaction [Zidovudine results in increased expression of RELA protein]; glutapyrone inhibits the reaction [Zidovudine results in increased expression of RELA protein]; tauropyrone inhibits the reaction [Zidovudine results in increased expression of RELA protein]
Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Hydralazine inhibits the reaction [Acrolein promotes the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]]; Hydralazine inhibits the reaction [Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]]; Zidovudine promotes the reaction [Acrolein promotes the reaction [RELA protein binds to FASLG promoter]]; Zidovudine promotes the reaction [RELA protein binds to FASLG promoter]
CTD PMID:18801031 PMID:27238871 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1306233 similar to hypothetical protein MGC29761 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of C9ORF116 mRNA CTD PMID:20370541 NCBI chr 3:7,047,603...7,051,953
Ensembl chr 3:7,047,603...7,051,953
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr 4:170,762,862...170,763,962
Ensembl chr 4:170,763,605...170,763,916
JBrowse link
G Rgs6 regulator of G-protein signaling 6 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of RGS6 mRNA CTD PMID:20370541 NCBI chr 6:106,310,442...106,598,668
Ensembl chr 6:106,496,992...106,602,139
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNA CTD PMID:15784690 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:14,083,538...14,088,011
Ensembl chr10:14,083,538...14,085,855
JBrowse link
G Rnf213 ring finger protein 213 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of RNF213 mRNA CTD PMID:20370541 NCBI chr10:108,527,351...108,626,372
Ensembl chr10:108,527,740...108,624,688
JBrowse link
G Rpa1 replication protein A1 increases expression ISO Zidovudine results in increased expression of RPA1 mRNA CTD PMID:21192964 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:57,606,287...57,613,834
Ensembl chr10:57,606,650...57,613,747
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Zidovudine results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of RSAD2 mRNA CTD PMID:20370541 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of S100A8 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G Sapcd2 suppressor APC domain containing 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of SAPCD2 mRNA CTD PMID:20370541 NCBI chr 3:2,590,355...2,597,283
Ensembl chr 3:2,591,331...2,596,583
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SCIMP mRNA CTD PMID:20370541 NCBI chr10:57,415,429...57,436,412
Ensembl chr10:57,415,832...57,436,368
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of SDHB mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of SDHB mRNA
CTD PMID:16894629 PMID:18313992 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D increases expression ISO Zidovudine results in increased expression of SDHD mRNA CTD PMID:16894629 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604
JBrowse link
G Serinc1 serine incorporator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SERINC1 mRNA CTD PMID:16931933 NCBI chr20:38,966,016...38,985,056
Ensembl chr20:38,967,238...38,985,036
JBrowse link
G Serping1 serpin family G member 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SERPING1 mRNA CTD PMID:20370541 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN1 mRNA CTD PMID:18313992 NCBI chr17:11,046,588...11,082,219
Ensembl chr17:11,045,761...11,082,047
JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN2 mRNA CTD PMID:18313992 NCBI chr 1:266,333,440...266,345,736
Ensembl chr 1:266,333,440...266,345,697
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN4 mRNA CTD PMID:18313992 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA CTD PMID:18313992 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
G Shfl shiftless antiviral inhibitor of ribosomal frameshifting multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SHFL mRNA CTD PMID:20370541 NCBI chr 8:21,890,214...21,896,045
Ensembl chr 8:21,890,319...21,896,031
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SIGLEC1 mRNA CTD PMID:20370541 NCBI chr 3:123,612,067...123,631,718
Ensembl chr 3:123,612,067...123,631,109
JBrowse link
G Sirt3 sirtuin 3 increases expression ISO Zidovudine results in increased expression of SIRT3 protein CTD PMID:27041070 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Slc10a3 solute carrier family 10, member 3 increases expression ISO Zidovudine results in increased expression of SLC10A3 mRNA CTD PMID:24292225 NCBI chr  X:156,335,385...156,340,256
Ensembl chr  X:156,336,450...156,340,234
JBrowse link
G Slc12a3 solute carrier family 12 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC12A3 mRNA CTD PMID:24292225 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641
JBrowse link
G Slc12a4 solute carrier family 12 member 4 increases expression ISO Zidovudine results in increased expression of SLC12A4 mRNA CTD PMID:24292225 NCBI chr19:37,917,003...37,938,952
Ensembl chr19:37,917,014...37,938,857
JBrowse link
G Slc12a9 solute carrier family 12, member 9 increases expression ISO Zidovudine results in increased expression of SLC12A9 mRNA CTD PMID:24292225 NCBI chr12:22,434,845...22,451,265
Ensembl chr12:22,434,814...22,451,263
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression
decreases expression
ISO Zidovudine results in increased expression of SLC13A3 mRNA
Zidovudine results in decreased expression of SLC13A3 mRNA
CTD PMID:24292225 NCBI chr 3:162,084,336...162,147,398
Ensembl chr 3:162,084,315...162,147,393
JBrowse link
G Slc13a5 solute carrier family 13 member 5 decreases expression
increases expression
ISO Zidovudine results in decreased expression of SLC13A5 mRNA
Zidovudine results in increased expression of SLC13A5 mRNA
CTD PMID:24292225 NCBI chr10:58,806,581...58,835,549
Ensembl chr10:58,810,058...58,834,538
JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression ISO Zidovudine results in decreased expression of SLC16A1 mRNA CTD PMID:24292225 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a2 solute carrier family 16 member 2 increases expression ISO Zidovudine results in increased expression of SLC16A2 mRNA CTD PMID:24292225 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC16A3 mRNA CTD PMID:24292225 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc16a4 solute carrier family 16, member 4 increases expression ISO Zidovudine results in increased expression of SLC16A4 mRNA CTD PMID:24292225 NCBI chr 2:210,045,122...210,161,017
Ensembl chr 2:210,045,161...210,068,502
JBrowse link
G Slc16a6 solute carrier family 16, member 6 decreases expression
increases expression
ISO Zidovudine results in decreased expression of SLC16A6 mRNA
Zidovudine results in increased expression of SLC16A6 mRNA
CTD PMID:24292225 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc17a2 solute carrier family 17, member 2 decreases expression ISO Zidovudine results in decreased expression of SLC17A2 mRNA CTD PMID:24292225 NCBI chr17:43,567,528...43,584,228
Ensembl chr17:43,567,528...43,584,152
JBrowse link
G Slc17a8 solute carrier family 17 member 8 increases expression ISO Zidovudine results in increased expression of SLC17A8 mRNA CTD PMID:24292225 NCBI chr 7:30,215,231...30,274,993
Ensembl chr 7:30,216,104...30,274,984
JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression ISO Zidovudine results in decreased expression of SLC19A2 mRNA CTD PMID:24292225 NCBI chr13:82,552,586...82,566,586
Ensembl chr13:82,552,550...82,566,586
JBrowse link
G Slc19a3 solute carrier family 19 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC19A3 mRNA CTD PMID:24292225 NCBI chr 9:88,762,775...88,828,553
Ensembl chr 9:88,764,073...88,816,898
JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression ISO Zidovudine results in increased expression of SLC1A1 mRNA CTD PMID:24292225 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A4 mRNA
Zidovudine results in increased expression of SLC1A4 mRNA
CTD PMID:15784690 PMID:24292225 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A5 mRNA CTD PMID:15784690 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases expression ISO Zidovudine results in decreased expression of SLC20A1 mRNA CTD PMID:24292225 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc20a2 solute carrier family 20 member 2 increases expression ISO Zidovudine results in increased expression of SLC20A2 mRNA CTD PMID:24292225 NCBI chr16:74,318,287...74,408,030
Ensembl chr16:74,317,899...74,408,030
JBrowse link
G Slc22a15 solute carrier family 22, member 15 decreases expression ISO Zidovudine results in decreased expression of SLC22A15 mRNA CTD PMID:24292225 NCBI chr 2:204,281,638...204,344,026
Ensembl chr 2:204,281,638...204,341,676
JBrowse link
G Slc22a17 solute carrier family 22, member 17 increases expression ISO Zidovudine results in increased expression of SLC22A17 mRNA CTD PMID:24292225 NCBI chr15:33,569,824...33,576,972
Ensembl chr15:33,569,843...33,576,331
JBrowse link
G Slc22a18 solute carrier family 22, member 18 increases expression ISO Zidovudine results in increased expression of SLC22A18 mRNA CTD PMID:24292225 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641
JBrowse link
G Slc22a23 solute carrier family 22, member 23 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SLC22A23 mRNA CTD PMID:20370541 NCBI chr17:31,236,015...31,403,685
Ensembl chr17:31,236,015...31,403,685
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO Zidovudine results in decreased expression of SLC22A9 mRNA CTD PMID:24292225 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases expression ISO Zidovudine results in increased expression of SLC22A4 mRNA CTD PMID:24292225 NCBI chr10:39,334,972...39,373,508 JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression ISO Zidovudine results in increased expression of SLC22A5 mRNA CTD PMID:24292225 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases uptake
increases expression
ISO SLC22A7 protein results in increased uptake of Zidovudine
Zidovudine results in increased expression of SLC22A7 mRNA
CTD PMID:15901346 PMID:24292225 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc23a2 solute carrier family 23 member 2 increases expression ISO Zidovudine results in increased expression of SLC23A2 mRNA CTD PMID:24292225 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252
JBrowse link
G Slc24a4 solute carrier family 24 member 4 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SLC24A4 mRNA CTD PMID:20370541 NCBI chr 6:126,015,799...126,158,727
Ensembl chr 6:126,018,841...126,153,867
JBrowse link
G Slc25a1 solute carrier family 25 member 1 increases expression ISO Zidovudine results in increased expression of SLC25A1 mRNA CTD PMID:24292225 NCBI chr11:87,204,248...87,207,265
Ensembl chr11:87,204,175...87,207,264
JBrowse link
G Slc25a10 solute carrier family 25 member 10 increases expression ISO Zidovudine results in increased expression of SLC25A10 mRNA CTD PMID:24292225 NCBI chr10:109,665,682...109,674,782
Ensembl chr10:109,665,682...109,673,143
JBrowse link
G Slc25a11 solute carrier family 25 member 11 increases expression ISO Zidovudine results in increased expression of SLC25A11 mRNA CTD PMID:24292225 NCBI chr10:57,265,903...57,268,018
Ensembl chr10:57,265,704...57,268,081
JBrowse link
G Slc25a12 solute carrier family 25 member 12 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A12 mRNA CTD PMID:18313992 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A15 mRNA CTD PMID:18313992 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc25a16 solute carrier family 25 member 16 increases expression ISO Zidovudine results in increased expression of SLC25A16 mRNA CTD PMID:24292225 NCBI chr20:27,283,383...27,308,069
Ensembl chr20:27,254,984...27,308,069
JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Zidovudine co-treated with Lamivudine co-treated with Indinavir]
[Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A19 mRNA
CTD PMID:15951836 PMID:18313992 NCBI chr10:104,166,594...104,179,523
Ensembl chr10:104,166,598...104,179,523
JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A2 mRNA CTD PMID:18313992 NCBI chr18:30,774,205...30,775,401
Ensembl chr18:30,774,205...30,775,401
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A20 mRNA
Zidovudine results in increased expression of SLC25A20 mRNA
CTD PMID:18313992 PMID:24292225 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc25a21 solute carrier family 25 member 21 increases expression ISO Zidovudine results in increased expression of SLC25A21 mRNA CTD PMID:24292225 NCBI chr 6:77,624,384...78,121,339
Ensembl chr 6:77,624,385...77,848,434
JBrowse link
G Slc25a29 solute carrier family 25 member 29 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNA CTD PMID:18313992 NCBI chr 6:132,736,964...132,747,912
Ensembl chr 6:132,735,883...132,747,828
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A3 mRNA CTD PMID:18313992 NCBI chr 7:31,816,601...31,824,064
Ensembl chr 7:31,816,602...31,824,071
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A4 mRNA CTD PMID:18313992 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc26a1 solute carrier family 26 member 1 increases expression ISO Zidovudine results in increased expression of SLC26A1 mRNA CTD PMID:24292225 NCBI chr14:2,050,805...2,056,091
Ensembl chr14:2,050,483...2,056,089
JBrowse link
G Slc26a11 solute carrier family 26 member 11 increases expression ISO Zidovudine results in increased expression of SLC26A11 mRNA CTD PMID:24292225 NCBI chr10:108,479,105...108,504,188
Ensembl chr10:108,480,368...108,503,706
JBrowse link
G Slc26a2 solute carrier family 26 member 2 increases expression ISO Zidovudine results in increased expression of SLC26A2 mRNA CTD PMID:24292225 NCBI chr18:56,518,999...56,534,539
Ensembl chr18:56,520,740...56,534,415
JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC26A3 mRNA CTD PMID:24292225 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300
JBrowse link
G Slc26a9 solute carrier family 26 member 9 increases expression ISO Zidovudine results in increased expression of SLC26A9 mRNA CTD PMID:24292225 NCBI chr13:48,512,415...48,539,467
Ensembl chr13:48,513,008...48,539,467
JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression ISO Zidovudine results in increased expression of SLC27A2 mRNA CTD PMID:24292225 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc28a1 solute carrier family 28 member 1 affects transport
multiple interactions
increases uptake
ISO
EXP
SLC28A1 protein affects the transport of Zidovudine
Zidovudine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]; Zidovudine promotes the reaction [SLC28A1 protein results in increased export of Uridine]
SLC28A1 protein results in increased uptake of Zidovudine
CTD PMID:8027026 PMID:8700147 PMID:8713072 PMID:9124315 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc28a3 solute carrier family 28 member 3 increases expression ISO Zidovudine results in increased expression of SLC28A3 mRNA CTD PMID:24292225 NCBI chr17:6,459,024...6,509,761
Ensembl chr17:6,459,056...6,509,799
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO Zidovudine results in increased expression of SLC29A1 mRNA CTD PMID:24292225 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport
increases expression
ISO SLC29A3 protein affects the transport of Zidovudine
Zidovudine results in increased expression of SLC29A3 mRNA
CTD PMID:19164483 PMID:24292225 NCBI chr20:30,289,527...30,327,343
Ensembl chr20:30,287,424...30,327,361
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Zidovudine results in decreased expression of SLC2A1 mRNA CTD PMID:24292225 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a10 solute carrier family 2 member 10 decreases expression ISO Zidovudine results in decreased expression of SLC2A10 mRNA CTD PMID:24292225 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC2A3 mRNA CTD PMID:24292225 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a4 solute carrier family 2 member 4 affects expression ISO Zidovudine affects the expression of SLC2A4 mRNA CTD PMID:20032539 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Zidovudine results in increased expression of SLC2A6 mRNA CTD PMID:24292225 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc2a8 solute carrier family 2 member 8 increases expression ISO Zidovudine results in increased expression of SLC2A8 mRNA CTD PMID:24292225 NCBI chr 3:12,020,227...12,029,920
Ensembl chr 3:12,020,229...12,029,877
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO Zidovudine results in increased expression of SLC30A1 mRNA CTD PMID:24292225 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc30a3 solute carrier family 30 member 3 increases expression ISO Zidovudine results in increased expression of SLC30A3 mRNA CTD PMID:24292225 NCBI chr 6:26,629,752...26,650,106
Ensembl chr 6:26,642,783...26,650,105
JBrowse link
G Slc30a7 solute carrier family 30 member 7 increases expression ISO Zidovudine results in increased expression of SLC30A7 mRNA CTD PMID:24292225 NCBI chr 2:218,888,431...218,951,030
Ensembl chr 2:218,888,431...218,951,030
JBrowse link
G Slc30a9 solute carrier family 30 member 9 increases expression ISO Zidovudine results in increased expression of SLC30A9 mRNA CTD PMID:24292225 NCBI chr14:42,464,814...42,519,760
Ensembl chr14:42,465,807...42,520,020
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC31A1 mRNA CTD PMID:15784690 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc31a2 solute carrier family 31 member 2 increases expression ISO Zidovudine results in increased expression of SLC31A2 mRNA CTD PMID:24292225 NCBI chr 5:78,120,606...78,131,111
Ensembl chr 5:78,120,607...78,131,114
JBrowse link
G Slc35a4 solute carrier family 35, member A4 increases expression ISO Zidovudine results in increased expression of SLC35A4 mRNA CTD PMID:24292225 NCBI chr18:29,505,239...29,509,304
Ensembl chr18:29,506,128...29,509,296
JBrowse link
G Slc35b3 solute carrier family 35 member B3 increases expression ISO Zidovudine results in increased expression of SLC35B3 mRNA CTD PMID:24292225 NCBI chr17:26,478,777...26,505,225
Ensembl chr17:26,478,315...26,504,738
JBrowse link
G Slc35b4 solute carrier family 35 member B4 increases expression ISO Zidovudine results in increased expression of SLC35B4 mRNA CTD PMID:24292225 NCBI chr 4:61,550,995...61,573,003
Ensembl chr 4:61,550,995...61,573,003
JBrowse link
G Slc35d1 solute carrier family 35 member D1 increases expression ISO Zidovudine results in increased expression of SLC35D1 mRNA CTD PMID:24292225 NCBI chr 5:122,700,396...122,746,815
Ensembl chr 5:122,699,587...122,746,839
JBrowse link
G Slc35f2 solute carrier family 35, member F2 increases expression ISO Zidovudine results in increased expression of SLC35F2 mRNA CTD PMID:24292225 NCBI chr 8:58,347,474...58,391,462
Ensembl chr 8:58,347,736...58,391,599
JBrowse link
G Slc37a1 solute carrier family 37 member 1 increases expression ISO Zidovudine results in increased expression of SLC37A1 mRNA CTD PMID:24292225 NCBI chr20:10,026,839...10,087,691
Ensembl chr20:10,032,641...10,087,688
JBrowse link
G Slc37a2 solute carrier family 37 member 2 increases expression ISO Zidovudine results in increased expression of SLC37A2 mRNA CTD PMID:24292225 NCBI chr 8:39,708,678...39,735,042
Ensembl chr 8:39,708,638...39,734,594
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO Zidovudine results in decreased expression of SLC38A2 mRNA CTD PMID:24292225 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc38a3 solute carrier family 38, member 3 increases expression ISO Zidovudine results in increased expression of SLC38A3 mRNA CTD PMID:24292225 NCBI chr 8:116,406,258...116,423,752
Ensembl chr 8:116,406,241...116,422,366
JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression ISO Zidovudine results in decreased expression of SLC38A4 mRNA CTD PMID:24292225 NCBI chr 7:138,459,576...138,512,952
Ensembl chr 7:138,459,504...138,512,952
JBrowse link
G Slc38a5 solute carrier family 38, member 5 decreases expression ISO Zidovudine results in decreased expression of SLC38A5 mRNA CTD PMID:24292225 NCBI chr  X:14,963,919...14,972,675
Ensembl chr  X:14,963,921...14,972,675
JBrowse link
G Slc38a6 solute carrier family 38, member 6 increases expression ISO Zidovudine results in increased expression of SLC38A6 mRNA CTD PMID:24292225 NCBI chr 6:96,171,756...96,241,512
Ensembl chr 6:96,171,756...96,241,096
JBrowse link
G Slc39a10 solute carrier family 39 member 10 decreases expression ISO Zidovudine results in decreased expression of SLC39A10 mRNA CTD PMID:24292225 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc39a14 solute carrier family 39 member 14 decreases expression ISO Zidovudine results in decreased expression of SLC39A14 mRNA CTD PMID:24292225 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Slc39a9 solute carrier family 39, member 9 increases expression ISO Zidovudine results in increased expression of SLC39A9 mRNA CTD PMID:24292225 NCBI chr 6:104,291,001...104,326,553
Ensembl chr 6:104,291,071...104,329,872
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC3A2 mRNA
Zidovudine results in increased expression of SLC3A2 mRNA
CTD PMID:15784690 PMID:24292225 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNA
Zidovudine results in increased expression of SLC40A1 mRNA
CTD PMID:18313992 PMID:24292225 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression ISO Zidovudine results in increased expression of SLC4A2 mRNA CTD PMID:24292225 NCBI chr 4:7,264,677...7,282,355
Ensembl chr 4:7,264,683...7,281,223
JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO Zidovudine results in decreased expression of SLC5A3 mRNA CTD PMID:24292225 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Slc6a11 solute carrier family 6 member 11 increases expression ISO Zidovudine results in increased expression of SLC6A11 mRNA CTD PMID:24292225 NCBI chr 4:146,106,386...146,223,228
Ensembl chr 4:146,106,386...146,223,228
JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression ISO Zidovudine results in increased expression of SLC6A12 mRNA CTD PMID:24292225 NCBI chr 4:153,921,199...153,941,333
Ensembl chr 4:153,921,115...153,941,391
JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases expression ISO Zidovudine results in increased expression of SLC6A2 mRNA CTD PMID:24292225 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc6a8 solute carrier family 6 member 8 decreases expression ISO Zidovudine results in decreased expression of SLC6A8 mRNA CTD PMID:24292225 NCBI chr  X:157,129,987...157,139,321
Ensembl chr  X:157,129,987...157,139,291
JBrowse link
G Slc7a10 solute carrier family 7 member 10 decreases expression
increases expression
ISO Zidovudine results in decreased expression of SLC7A10 mRNA
Zidovudine results in increased expression of SLC7A10 mRNA
CTD PMID:24292225 NCBI chr 1:91,432,952...91,448,566
Ensembl chr 1:91,433,030...91,448,564
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO Zidovudine results in decreased expression of SLC7A2 mRNA CTD PMID:24292225 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Zidovudine results in increased expression of SLC7A5 mRNA CTD PMID:24292225 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slc7a7 solute carrier family 7 member 7 multiple interactions
increases expression
ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of SLC7A7 mRNA
Zidovudine results in increased expression of SLC7A7 mRNA
CTD PMID:20370541 PMID:24292225 NCBI chr15:33,013,346...33,059,733
Ensembl chr15:33,013,504...33,051,129
JBrowse link
G Slc7a8 solute carrier family 7 member 8 increases expression ISO Zidovudine results in increased expression of SLC7A8 mRNA CTD PMID:24292225 NCBI chr15:33,369,245...33,428,942
Ensembl chr15:33,369,216...33,428,973
JBrowse link
G Slc7a9 solute carrier family 7 member 9 increases expression ISO Zidovudine results in increased expression of SLC7A9 mRNA CTD PMID:24292225 NCBI chr 1:91,709,034...91,738,492
Ensembl chr 1:91,716,383...91,738,494
JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression ISO Zidovudine results in increased expression of SLC9A1 mRNA CTD PMID:24292225 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression ISO Zidovudine results in decreased expression of SLCO2A1 mRNA CTD PMID:24292225 NCBI chr 8:111,495,443...111,577,320
Ensembl chr 8:111,495,331...111,577,833
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression
increases expression
ISO Zidovudine results in decreased expression of SLCO2B1 mRNA
Zidovudine results in increased expression of SLCO2B1 mRNA
CTD PMID:24292225 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 decreases expression ISO Zidovudine results in decreased expression of SLCO4A1 mRNA CTD PMID:24292225 NCBI chr 3:175,838,994...175,857,985
Ensembl chr 3:175,838,994...175,857,983
JBrowse link
G Sod2 superoxide dismutase 2 decreases response to substance
multiple interactions
ISO
EXP
SOD2 protein results in decreased susceptibility to Zidovudine
[SOD2 co-treated with CYP3A4] affects the susceptibility to Zidovudine
CTD PMID:19398959 PMID:19501153 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
G Sqstm1 sequestosome 1 increases expression EXP Zidovudine results in increased expression of SQSTM1 protein CTD PMID:29594326 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of STAR mRNA CTD PMID:18313992 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of STAT1 mRNA CTD PMID:20370541 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of STAT2 mRNA CTD PMID:20370541 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of STC2 mRNA CTD PMID:15784690 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Sub1 SUB1 regulator of transcription multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SUB1 mRNA CTD PMID:16931933 NCBI chr 2:62,019,902...62,034,704
Ensembl chr 2:62,022,567...62,034,628
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TCEA1 mRNA CTD PMID:15784690 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tcn2 transcobalamin 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TCN2 mRNA CTD PMID:20370541 NCBI chr14:84,173,992...84,189,299
Ensembl chr14:84,174,138...84,189,266
JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO Zidovudine results in decreased activity of TERT protein CTD PMID:16601281 PMID:18097608 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression EXP Zidovudine results in increased expression of TFAM mRNA CTD PMID:10535663 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Zidovudine results in decreased expression of TFAP2A mRNA CTD PMID:17926646 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tfeb transcription factor EB decreases expression EXP Zidovudine results in decreased expression of TFEB protein CTD PMID:29594326 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM17B mRNA CTD PMID:18313992 NCBI chr  X:15,441,369...15,448,452
Ensembl chr  X:15,441,651...15,448,403
Ensembl chr  X:15,441,651...15,448,403
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA CTD PMID:18313992 NCBI chr16:8,324,038...8,350,067
Ensembl chr16:8,324,036...8,350,067
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tk1 thymidine kinase 1 decreases response to substance
increases expression
decreases expression
increases mutagenesis
increases response to substance
increases metabolic processing
increases activity
increases methylation
decreases activity
affects transport
multiple interactions
ISO TK1 gene modified form results in decreased susceptibility to Zidovudine
Zidovudine results in increased expression of TK1 mRNA; Zidovudine results in increased expression of TK1 protein
Zidovudine results in decreased expression of TK1 mRNA; Zidovudine results in decreased expression of TK1 protein
Zidovudine results in increased mutagenesis of TK1 gene
TK1 protein results in increased susceptibility to Zidovudine
TK1 protein results in increased metabolism of Zidovudine
Zidovudine results in increased activity of TK1 protein
Zidovudine results in increased methylation of TK1 exon
Zidovudine results in decreased activity of TK1 protein
TK1 protein affects the transport of Zidovudine
Ethanol inhibits the reaction [Zidovudine results in increased activity of TK1 protein]; Zidovudine inhibits the reaction [Ethanol results in decreased activity of TK1 protein]
CTD PMID:8915012 PMID:8941356 PMID:11923581 PMID:15013700 PMID:15708581 PMID:17067265 PMID:19237551 PMID:20106944 PMID:24292225 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tk2 thymidine kinase 2 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TK2 mRNA
Zidovudine results in increased expression of TK2 mRNA
CTD PMID:18313992 PMID:24292225 NCBI chr19:917,203...939,236
Ensembl chr19:917,203...939,221
JBrowse link
G Tlr7 toll-like receptor 7 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TLR7 mRNA CTD PMID:20370541 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tmem97 transmembrane protein 97 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of TMEM97 mRNA CTD PMID:20370541 NCBI chr10:65,811,455...65,820,538
Ensembl chr10:65,811,456...65,820,538
JBrowse link
G Tnc tenascin C multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of TNC mRNA CTD PMID:20370541 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
increases expression
ISO
EXP
Zidovudine analog results in decreased expression of TNF protein
[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein; silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein]
Zidovudine results in increased expression of TNF protein
CTD PMID:12729831 PMID:17668557 PMID:28619387 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TNFSF10 mRNA CTD PMID:20370541 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf13b TNF superfamily member 13b multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TNFSF13B mRNA CTD PMID:20370541 NCBI chr16:85,275,690...85,306,419
Ensembl chr16:85,275,678...85,306,366
JBrowse link
G Tnni2 troponin I2, fast skeletal type multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TNNI2 mRNA CTD PMID:20370541 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Tnni3 troponin I3, cardiac type affects localization ISO Zidovudine affects the localization of TNNI3 protein CTD PMID:17943461 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Zidovudine results in increased expression of TP53 protein CTD PMID:16797627 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of TRDMT1 mRNA CTD PMID:20370541 NCBI chr17:80,824,652...80,859,585
Ensembl chr17:80,826,846...80,860,195
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TRIB3 mRNA CTD PMID:15784690 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:105,205,041...105,226,541
Ensembl chr 8:105,204,993...105,226,588
JBrowse link
G Triqk triple QxxK/R motif containing multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of TRIQK mRNA CTD PMID:20370541 NCBI chr 5:26,493,185...26,567,491
Ensembl chr 5:26,493,212...26,566,370
JBrowse link
G Trmt44 tRNA methyltransferase 44 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TRMT44 mRNA CTD PMID:20370541 NCBI chr14:80,361,490...80,379,408
Ensembl chr14:80,361,294...80,383,138
JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of TTC21A mRNA CTD PMID:20370541 NCBI chr 8:128,622,414...128,657,199
Ensembl chr 8:128,622,428...128,657,955
JBrowse link
G Twnk twinkle mtDNA helicase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TWNK mRNA CTD PMID:18313992 NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
JBrowse link
G Tymp thymidine phosphorylase multiple interactions
increases expression
increases activity
ISO [5-chloro-6-(1-(2-iminopyrrolidinyl) methyl)uracil hydrochloride results in decreased activity of TYMP protein] results in decreased susceptibility to [Zidovudine co-treated with doxifluridine]; [Zidovudine results in increased activity of TYMP protein] which results in increased susceptibility to doxifluridine
Zidovudine results in increased expression of TYMP mRNA; Zidovudine results in increased expression of TYMP protein
CTD PMID:16457948 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYRP1 mRNA CTD PMID:15784690 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Ucp1 uncoupling protein 1 increases expression
decreases expression
ISO Zidovudine results in increased expression of UCP1 mRNA
Zidovudine results in decreased expression of UCP1 mRNA
CTD PMID:14518702 PMID:17926646 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of Zidovudine CTD PMID:8302279 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation
multiple interactions
decreases expression
increases expression
ISO UGT2B7 protein results in increased glucuronidation of Zidovudine
10-hydroxywarfarin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Zidovudine]; 4'-hydroxywarfarin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Zidovudine]; 7-hydroxywarfarin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Zidovudine]; [10-hydroxywarfarin binds to and results in decreased activity of UGT2B7 protein] which results in decreased glucuronidation of Zidovudine; [4'-hydroxywarfarin binds to and results in decreased activity of UGT2B7 protein] which results in decreased glucuronidation of Zidovudine; [7-hydroxywarfarin binds to and results in decreased activity of UGT2B7 protein] which results in decreased glucuronidation of Zidovudine; [Warfarin binds to and results in decreased activity of UGT2B7 protein] which results in decreased glucuronidation of Zidovudine; shikonin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Zidovudine]; Warfarin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Zidovudine]
Zidovudine results in decreased expression of UGT2B7 mRNA; Zidovudine results in decreased expression of UGT2B7 protein
Zidovudine results in increased expression of UGT2B7 mRNA; Zidovudine results in increased expression of UGT2B7 protein
CTD PMID:10772627 PMID:17898154 PMID:24292225 PMID:25393417 PMID:31128210 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases phosphorylation EXP Zidovudine results in decreased phosphorylation of ULK1 protein CTD PMID:29594326 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRB mRNA CTD PMID:18313992 NCBI chr 7:71,264,501...71,269,869
Ensembl chr 7:71,264,514...71,269,869
Ensembl chr 1:71,264,514...71,269,869
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRC1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of UQCRC2 mRNA CTD PMID:18313992 NCBI chr 1:190,555,177...190,585,741
Ensembl chr 1:190,555,177...190,585,734
JBrowse link
G Usp18 ubiquitin specific peptidase 18 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of USP18 mRNA CTD PMID:20370541 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDAC1 mRNA CTD PMID:18313992 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA CTD PMID:11741158 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA CTD PMID:16931933 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of WARS1 mRNA CTD PMID:15784690 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wdr62 WD repeat domain 62 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in decreased expression of WDR62 mRNA CTD PMID:20370541 NCBI chr 1:90,995,545...91,034,592
Ensembl chr 1:88,694,824...88,734,223
JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of WNT10A mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:82,053,581...82,066,047
Ensembl chr 9:82,053,581...82,066,047
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression ISO Zidovudine results in increased expression of XPA mRNA; Zidovudine results in increased expression of XPA protein CTD PMID:21192964 PMID:23675285 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases response to substance
increases expression
ISO XPC protein results in decreased susceptibility to Zidovudine
Zidovudine results in increased expression of XPC mRNA; Zidovudine results in increased expression of XPC protein
CTD PMID:21192964 PMID:23675285 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of YARS1 mRNA CTD PMID:15784690 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
G Zfp629 zinc finger protein 629 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of ZNF629 mRNA CTD PMID:20370541 NCBI chr 1:199,052,430...199,065,639
Ensembl chr 1:198,894,000...199,064,150
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      atom 19768
        nonmetal atom 19651
          nitrogen atom 18582
            nitrogen molecular entity 18582
              nucleobase-containing molecular entity 5342
                nucleoside 5342
                  deoxyribonucleoside 2736
                    2',3'-dideoxyribonucleoside 557
                      purine 2',3'-dideoxyribonucleoside + 8
                      pyrimidine 2',3'-dideoxyribonucleoside + 552
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            heteroorganic entity 19206
                              organochalcogen compound 18951
                                organooxygen compound 18877
                                  carbohydrates and carbohydrate derivatives 12259
                                    carbohydrate 12259
                                      carbohydrate derivative 11889
                                        glycosyl compound 10958
                                          N-glycosyl compound 5480
                                            nucleoside 5342
                                              deoxyribonucleoside 2736
                                                2',3'-dideoxyribonucleoside 557
                                                  purine 2',3'-dideoxyribonucleoside + 8
                                                  pyrimidine 2',3'-dideoxyribonucleoside + 552
paths to the root