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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-oxo monocarboxylic acid
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Accession:CHEBI:47881 term browser browse the term
Synonyms:related_synonym: 3-Keto acid;   3-Oxo acid;   3-oxo monocarboxylic acids;   3-oxomonocarboxylic acid;   3-oxomonocarboxylic acids;   Formula=C3H2O3R2
 alt_id: CHEBI:13600;   CHEBI:1619;   CHEBI:35949
 xref: KEGG:C01656
 cyclic_relationship: is_conjugate_acid_of CHEBI:35973



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acetoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO acetoacetic acid results in increased secretion of CCL2 protein CTD PMID:17665966 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Il6 interleukin 6 increases secretion ISO acetoacetic acid results in increased secretion of IL6 protein CTD PMID:17665966 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Slc13a5 solute carrier family 13 member 5 decreases abundance ISO SLC13A5 protein results in decreased abundance of acetoacetic acid CTD PMID:32634519 NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945
JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
flumequine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL2 mRNA CTD PMID:23681119 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL3 mRNA CTD PMID:23681119 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL4 mRNA CTD PMID:23681119 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCL7 mRNA CTD PMID:23681119 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNA2 mRNA CTD PMID:23681119 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNB1 mRNA; flumequine promotes the reaction [estragole results in increased expression of CCNB1 mRNA] CTD PMID:23681119 PMID:31029721 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNB2 mRNA CTD PMID:23681119 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCND1 mRNA
flumequine results in increased expression of CCND1 mRNA
CTD PMID:23681119 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNE1 mRNA; [flumequine co-treated with estragole] results in increased expression of CCNE1 mRNA CTD PMID:23681119 PMID:31029721 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCR2 mRNA CTD PMID:23681119 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCR7 mRNA CTD PMID:23681119 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CDK1 mRNA CTD PMID:23681119 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CHEK1 mRNA CTD PMID:23681119 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A1 mRNA CTD PMID:23681119 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA; [flumequine co-treated with estragole] results in increased expression of CYP1A2 mRNA CTD PMID:23681119 PMID:31029721 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP2B10 mRNA CTD PMID:23681119 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in decreased expression of CYP7B1 mRNA CTD PMID:23681119 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Exo1 exonuclease 1 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of EXO1 mRNA CTD PMID:23681119 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of FOS mRNA CTD PMID:23681119 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of IL1B mRNA CTD PMID:23681119 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il36b interleukin 36, beta multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in decreased expression of IL36B mRNA CTD PMID:23681119 NCBI chr 3:7,024,862...7,122,489
Ensembl chr 3:7,021,973...7,031,619
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of JUN mRNA CTD PMID:23681119 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of NFKB2 mRNA CTD PMID:23681119 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of RAD18 mRNA CTD PMID:23681119 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Rad51 RAD51 recombinase multiple interactions ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of RAD51 mRNA CTD PMID:23681119 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO [flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of TNF mRNA; [flumequine co-treated with estragole] results in increased expression of TNF mRNA
flumequine results in increased expression of TNF mRNA
CTD PMID:23681119 PMID:31029721 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression
multiple interactions
ISO flumequine results in decreased expression of UGT1A1 mRNA
[flumequine co-treated with estragole] results in decreased expression of UGT1A1 mRNA
CTD PMID:23681119 PMID:31029721 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression
multiple interactions
ISO flumequine results in decreased expression of UGT2B1 mRNA
[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in decreased expression of UGT2B1 mRNA
CTD PMID:23681119 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
levofloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd1 abhydrolase domain containing 1 decreases expression EXP Levofloxacin results in decreased expression of ABHD1 mRNA CTD PMID:24136188 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP Levofloxacin results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP Levofloxacin results in decreased expression of ACSL5 mRNA CTD PMID:24136188 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Levofloxacin results in decreased expression of ACTG1 mRNA CTD PMID:24136188 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Acy1 aminoacylase 1 decreases expression EXP Levofloxacin results in decreased expression of ACY1 mRNA CTD PMID:24136188 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
JBrowse link
G Afp alpha-fetoprotein decreases expression EXP Levofloxacin results in decreased expression of AFP mRNA CTD PMID:24136188 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP Levofloxacin results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression EXP Levofloxacin results in increased expression of ANGPTL6 mRNA CTD PMID:24136188 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Levofloxacin results in decreased expression of ANXA1 mRNA CTD PMID:24136188 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Levofloxacin results in decreased expression of ANXA2 mRNA CTD PMID:24136188 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression EXP Levofloxacin results in decreased expression of AP1S1 mRNA CTD PMID:24136188 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression EXP Levofloxacin results in increased expression of ARL4A mRNA CTD PMID:24136188 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
JBrowse link
G Aspa aspartoacylase decreases expression EXP Levofloxacin results in decreased expression of ASPA mRNA CTD PMID:24136188 NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
JBrowse link
G Atg2b autophagy related 2B increases expression EXP Levofloxacin results in increased expression of ATG2B mRNA CTD PMID:24136188 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 decreases expression EXP Levofloxacin results in decreased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [Levofloxacin co-treated with TNF protein] results in increased expression of BIRC2 mRNA CTD PMID:32035082 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Levofloxacin results in decreased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression EXP Levofloxacin results in decreased expression of BST2 mRNA CTD PMID:24136188 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression EXP Levofloxacin results in increased expression of BTG1 mRNA CTD PMID:24136188 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 decreases expression EXP Levofloxacin results in decreased expression of C2CD2 mRNA CTD PMID:24136188 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C4b complement C4B (Chido blood group) increases expression EXP Levofloxacin results in increased expression of C4B mRNA CTD PMID:24136188 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G C5 complement C5 increases expression EXP Levofloxacin results in increased expression of C5 mRNA CTD PMID:24136188 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression EXP Levofloxacin results in decreased expression of CAR14 mRNA CTD PMID:24136188 NCBI chr 2:183,442,263...183,449,207
Ensembl chr 2:183,441,667...183,449,693
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Levofloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein CTD PMID:30876886 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases expression EXP Levofloxacin results in increased expression of CCDC6 mRNA CTD PMID:24136188 NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression EXP Levofloxacin results in decreased expression of CCDC80 mRNA CTD PMID:24136188 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
JBrowse link
G Cd302 CD302 molecule increases expression EXP Levofloxacin results in increased expression of CD302 mRNA CTD PMID:24136188 NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression EXP Levofloxacin results in increased expression of CDC42EP4 mRNA CTD PMID:24136188 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Levofloxacin results in decreased expression of CDK1 mRNA CTD PMID:24136188 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Levofloxacin results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Levofloxacin results in increased expression of CEBPB mRNA CTD PMID:24136188 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cfhr1 complement factor H-related 1 increases expression EXP Levofloxacin results in increased expression of CFHR1 mRNA CTD PMID:24136188 NCBI chr13:51,395,583...51,410,571
Ensembl chr13:51,369,211...51,410,592
JBrowse link
G Cgn cingulin decreases expression EXP Levofloxacin results in decreased expression of CGN mRNA CTD PMID:24136188 NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression EXP Levofloxacin results in increased expression of CHPT1 mRNA CTD PMID:24136188 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP Levofloxacin results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clec14a C-type lectin domain containing 14A increases expression EXP Levofloxacin results in increased expression of CLEC14A mRNA CTD PMID:24136188 NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog decreases expression EXP Levofloxacin results in decreased expression of CMBL mRNA CTD PMID:24136188 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Levofloxacin results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP Levofloxacin results in increased expression of CYP27A1 mRNA CTD PMID:24136188 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Levofloxacin results in increased expression of CYP4B1 mRNA CTD PMID:24136188 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Levofloxacin results in increased expression of CYP51 mRNA CTD PMID:24136188 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Ddc dopa decarboxylase decreases expression EXP Levofloxacin results in decreased expression of DDC mRNA CTD PMID:24136188 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP Levofloxacin results in decreased expression of DDHD1 mRNA CTD PMID:24136188 NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO Levofloxacin results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 decreases expression EXP Levofloxacin results in decreased expression of DNAJC9 mRNA CTD PMID:24136188 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression EXP Levofloxacin results in decreased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression EXP Levofloxacin results in decreased expression of DTYMK mRNA CTD PMID:24136188 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression EXP Levofloxacin results in decreased expression of DUT mRNA CTD PMID:24136188 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Levofloxacin results in increased expression of EDEM1 mRNA CTD PMID:24136188 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression EXP Levofloxacin results in decreased expression of ELOVL5 mRNA CTD PMID:24136188 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Levofloxacin results in increased expression of ENC1 mRNA CTD PMID:24136188 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression EXP Levofloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Erg28 ergosterol biosynthesis 28 homolog increases expression EXP Levofloxacin results in increased expression of ERG28 mRNA CTD PMID:24136188 NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 decreases expression EXP Levofloxacin results in decreased expression of ERGIC1 mRNA CTD PMID:24136188 NCBI chr10:16,531,192...16,627,183
Ensembl chr10:16,531,194...16,626,957
JBrowse link
G Fgl1 fibrinogen-like 1 increases expression EXP Levofloxacin results in increased expression of FGL1 mRNA CTD PMID:24136188 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression EXP Levofloxacin results in decreased expression of FKBP4 mRNA CTD PMID:24136188 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Levofloxacin results in increased expression of FKBP5 mRNA CTD PMID:24136188 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flna filamin A decreases expression EXP Levofloxacin results in decreased expression of FLNA mRNA CTD PMID:24136188 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Fndc3b fibronectin type III domain containing 3B increases expression EXP Levofloxacin results in increased expression of FNDC3B mRNA CTD PMID:24136188 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
JBrowse link
G Fzd8 frizzled class receptor 8 increases expression EXP Levofloxacin results in increased expression of FZD8 mRNA CTD PMID:24136188 NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650
JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Levofloxacin results in increased expression of GAS6 mRNA CTD PMID:24136188 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Levofloxacin results in decreased expression of GCLC mRNA CTD PMID:24136188 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression EXP Levofloxacin results in decreased expression of GPD1 mRNA CTD PMID:24136188 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP Levofloxacin results in decreased expression of HACD3 mRNA CTD PMID:24136188 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Haus4 HAUS augmin-like complex, subunit 4 decreases expression EXP Levofloxacin results in decreased expression of HAUS4 mRNA CTD PMID:24136188 NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression EXP Levofloxacin results in increased expression of HERPUD1 mRNA CTD PMID:24136188 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP Levofloxacin results in decreased expression of HMGB2 mRNA CTD PMID:24136188 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 decreases expression EXP Levofloxacin results in decreased expression of HMGN2 mRNA CTD PMID:24136188 NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression EXP Levofloxacin results in decreased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO Levofloxacin results in decreased expression of ICAM1 mRNA
[Levofloxacin co-treated with TNF protein] results in increased expression of ICAM1 protein
CTD PMID:32035082 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP Levofloxacin results in increased expression of IDI1 mRNA CTD PMID:24136188 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifng interferon gamma increases expression EXP Levofloxacin results in increased expression of IFNG CTD PMID:24136188 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Levofloxacin results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Levofloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein CTD PMID:30876886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 increases expression ISO Levofloxacin results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Levofloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein CTD PMID:30876886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor increases expression EXP Levofloxacin results in increased expression of IL6R mRNA CTD PMID:24136188 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 increases expression EXP Levofloxacin results in increased expression of IP6K2 mRNA CTD PMID:24136188 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Ivns1abp influenza virus NS1A binding protein increases expression EXP Levofloxacin results in increased expression of IVNS1ABP mRNA CTD PMID:24136188 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression EXP Levofloxacin results in increased expression of KLF15 mRNA CTD PMID:24136188 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP Levofloxacin results in increased expression of KLF9 mRNA CTD PMID:24136188 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression EXP Levofloxacin results in decreased expression of KPNA2 mRNA CTD PMID:24136188 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression EXP Levofloxacin results in decreased expression of KPNB1 mRNA CTD PMID:24136188 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt18 keratin 18 decreases expression EXP Levofloxacin results in decreased expression of KRT18 mRNA CTD PMID:24136188 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Levofloxacin results in increased expression of LBP mRNA CTD PMID:24136188 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 decreases expression EXP Levofloxacin results in decreased expression of LCMT1 mRNA CTD PMID:24136188 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Lmnb1 lamin B1 decreases expression EXP Levofloxacin results in decreased expression of LMNB1 mRNA CTD PMID:24136188 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lmo7 LIM domain 7 decreases expression EXP Levofloxacin results in decreased expression of LMO7 mRNA CTD PMID:24136188 NCBI chr15:78,567,029...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G Lpin1 lipin 1 increases expression EXP Levofloxacin results in increased expression of LPIN1 mRNA CTD PMID:24136188 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like increases expression EXP Levofloxacin results in increased expression of LURAP1L mRNA CTD PMID:24136188 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
JBrowse link
G Manba mannosidase beta decreases expression EXP Levofloxacin results in decreased expression of MANBA mRNA CTD PMID:24136188 NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO [TNF protein co-treated with Levofloxacin] results in increased lipidation of MAP1LC3B protein; TNF protein promotes the reaction [Levofloxacin results in increased expression of MAP1LC3B protein] CTD PMID:33609687 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A increases expression EXP Levofloxacin results in increased expression of MFSD2A mRNA CTD PMID:24136188 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Levofloxacin results in increased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression EXP Levofloxacin results in decreased expression of NEDD9 mRNA CTD PMID:24136188 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression EXP Levofloxacin results in decreased expression of NFE2L2 mRNA CTD PMID:24136188 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
EXP
ISO
Levofloxacin results in increased expression of NFKBIA mRNA
[Levofloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA
CTD PMID:24136188 PMID:32035082 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression EXP Levofloxacin results in increased expression of NFKBIZ mRNA CTD PMID:24136188 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 increases expression EXP Levofloxacin results in increased expression of NRBP2 mRNA CTD PMID:24136188 NCBI chr 7:107,798,642...107,805,230
Ensembl chr 7:107,799,497...107,805,230
JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP Levofloxacin results in increased expression of NUDT4 mRNA CTD PMID:24136188 NCBI chr 7:30,188,100...30,204,620
Ensembl chr 7:30,188,100...30,204,615
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP Levofloxacin results in increased expression of NUPR1 mRNA CTD PMID:24136188 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Omd osteomodulin increases expression EXP Levofloxacin results in increased expression of OMD mRNA CTD PMID:24136188 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441
JBrowse link
G Osbpl1a oxysterol binding protein-like 1A decreases expression EXP Levofloxacin results in decreased expression of OSBPL1A mRNA CTD PMID:24136188 NCBI chr18:3,904,006...4,094,635
Ensembl chr18:3,904,006...4,094,585
JBrowse link
G Palmd palmdelphin decreases expression EXP Levofloxacin results in decreased expression of PALMD mRNA CTD PMID:24136188 NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP Levofloxacin results in increased expression of PBLD1 mRNA CTD PMID:24136188 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression
decreases expression
EXP
ISO
Levofloxacin results in increased expression of PID1 mRNA
Levofloxacin results in decreased expression of PID1 mRNA
CTD PMID:24136188 PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U increases expression EXP Levofloxacin results in increased expression of PIGU mRNA CTD PMID:24136188 NCBI chr 3:143,784,831...143,881,268
Ensembl chr 3:143,784,832...143,880,807
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP Levofloxacin results in increased expression of PLA2G12A mRNA CTD PMID:24136188 NCBI chr 2:218,436,450...218,452,760
Ensembl chr 2:218,436,513...218,452,740
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine decreases expression EXP Levofloxacin results in decreased expression of PLGRKT mRNA CTD PMID:24136188 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194
JBrowse link
G Plin3 perilipin 3 decreases expression EXP Levofloxacin results in decreased expression of PLIN3 mRNA CTD PMID:24136188 NCBI chr 9:1,111,178...1,123,117 JBrowse link
G Plp2 proteolipid protein 2 decreases expression EXP Levofloxacin results in decreased expression of PLP2 mRNA CTD PMID:24136188 NCBI chr  X:14,834,249...14,837,648
Ensembl chr  X:14,834,231...14,838,514
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit increases expression EXP Levofloxacin results in increased expression of POLG2 mRNA CTD PMID:24136188 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Levofloxacin results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP Levofloxacin results in increased expression of PPCS mRNA CTD PMID:24136188 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression EXP Levofloxacin results in decreased expression of PPIF mRNA CTD PMID:24136188 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A decreases expression EXP Levofloxacin results in decreased expression of PPP1R14A mRNA CTD PMID:24136188 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 decreases expression EXP Levofloxacin results in decreased expression of PRKAG2 mRNA CTD PMID:24136188 NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Proser2 proline and serine rich 2 increases expression EXP Levofloxacin results in increased expression of PROSER2 mRNA CTD PMID:24136188 NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
JBrowse link
G Prxl2b peroxiredoxin like 2B increases expression EXP Levofloxacin results in increased expression of PRXL2B mRNA CTD PMID:24136188 NCBI chr 5:165,462,610...165,465,213 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Levofloxacin results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP Levofloxacin results in decreased expression of PTTG1 mRNA CTD PMID:24136188 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression EXP Levofloxacin results in increased expression of RAPGEF4 mRNA CTD PMID:24136188 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Levofloxacin co-treated with Lipopolysaccharides] affects the localization of RELA protein CTD PMID:32035082 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Retreg1 reticulophagy regulator 1 increases expression EXP Levofloxacin results in increased expression of RETREG1 mRNA CTD PMID:24136188 NCBI chr 2:76,335,609...76,474,817 JBrowse link
G RGD1308742 similar to Complement C5 precursor increases expression EXP Levofloxacin results in increased expression of RGD1308742 mRNA CTD PMID:24136188 NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression EXP Levofloxacin results in decreased expression of RGD1309534 mRNA CTD PMID:24136188 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
JBrowse link
G RGD1311251 similar to RIKEN cDNA 4930550C14 increases expression EXP Levofloxacin results in increased expression of RGD1311251 mRNA CTD PMID:24136188 NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 decreases expression EXP Levofloxacin results in decreased expression of RMDN2 mRNA CTD PMID:24136188 NCBI chr 6:15,372,569...15,443,000
Ensembl chr 6:15,375,496...15,441,480
JBrowse link
G Rnd2 Rho family GTPase 2 increases expression EXP Levofloxacin results in increased expression of RND2 mRNA CTD PMID:24136188 NCBI chr10:86,399,177...86,402,750
Ensembl chr10:86,399,148...86,402,742
JBrowse link
G Rnf4 ring finger protein 4 decreases expression EXP Levofloxacin results in decreased expression of RNF4 mRNA CTD PMID:24136188 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Rnpepl1 arginyl aminopeptidase like 1 increases expression EXP Levofloxacin results in increased expression of RNPEPL1 mRNA CTD PMID:24136188 NCBI chr 9:93,476,600...93,486,331
Ensembl chr 9:93,472,390...93,486,331
JBrowse link
G Rpa1 replication protein A1 decreases expression EXP Levofloxacin results in decreased expression of RPA1 mRNA CTD PMID:24136188 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP Levofloxacin results in decreased expression of RRM2 mRNA CTD PMID:24136188 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression EXP Levofloxacin results in decreased expression of RSRP1 mRNA CTD PMID:24136188 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
JBrowse link
G Rxra retinoid X receptor alpha increases expression EXP Levofloxacin results in increased expression of RXRA mRNA CTD PMID:24136188 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sc5d sterol-C5-desaturase increases expression EXP Levofloxacin results in increased expression of SC5D mRNA CTD PMID:24136188 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Sdc4 syndecan 4 increases expression EXP Levofloxacin results in increased expression of SDC4 mRNA CTD PMID:24136188 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Serpina11 serpin family A member 11 increases expression EXP Levofloxacin results in increased expression of SERPINA11 mRNA CTD PMID:24136188 NCBI chr 6:122,903,246...122,912,695
Ensembl chr 6:122,903,250...122,912,670
JBrowse link
G Serpinh1 serpin family H member 1 decreases expression EXP Levofloxacin results in decreased expression of SERPINH1 mRNA CTD PMID:24136188 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Sesn2 sestrin 2 increases expression EXP Levofloxacin results in increased expression of SESN2 mRNA CTD PMID:24136188 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP Levofloxacin results in decreased expression of SFPQ mRNA CTD PMID:24136188 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 increases expression EXP Levofloxacin results in increased expression of SH3BP5 mRNA CTD PMID:24136188 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression EXP Levofloxacin results in increased expression of SLC13A3 mRNA CTD PMID:24136188 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression EXP Levofloxacin results in decreased expression of SLC17A3 mRNA CTD PMID:24136188 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression EXP Levofloxacin results in increased expression of SLC38A2 mRNA CTD PMID:24136188 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Levofloxacin results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Levofloxacin results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Spa17 sperm autoantigenic protein 17 decreases expression EXP Levofloxacin results in decreased expression of SPA17 mRNA CTD PMID:24136188 NCBI chr 8:37,307,432...37,318,645
Ensembl chr 8:37,307,557...37,318,639
JBrowse link
G Srxn1 sulfiredoxin 1 decreases expression EXP Levofloxacin results in decreased expression of SRXN1 mRNA CTD PMID:24136188 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Ssx2ip SSX family member 2 interacting protein decreases expression EXP Levofloxacin results in decreased expression of SSX2IP mRNA CTD PMID:24136188 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Levofloxacin results in increased expression of STAT3 mRNA CTD PMID:24136188 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Steap3 STEAP3 metalloreductase decreases expression EXP Levofloxacin results in decreased expression of STEAP3 mRNA CTD PMID:24136188 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Levofloxacin results in decreased expression of STMN1 mRNA CTD PMID:24136188 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sumf1 sulfatase modifying factor 1 increases expression EXP Levofloxacin results in increased expression of SUMF1 mRNA CTD PMID:24136188 NCBI chr 4:141,078,735...141,160,711
Ensembl chr 4:141,078,741...141,160,708
JBrowse link
G Synrg synergin, gamma increases expression EXP Levofloxacin results in increased expression of SYNRG mRNA CTD PMID:24136188 NCBI chr10:68,848,828...68,931,252 JBrowse link
G Syvn1 synoviolin 1 increases expression EXP Levofloxacin results in increased expression of SYVN1 mRNA CTD PMID:24136188 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 decreases expression EXP Levofloxacin results in decreased expression of TCIRG1 mRNA CTD PMID:24136188 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression EXP Levofloxacin results in increased expression of TEF mRNA CTD PMID:24136188 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
JBrowse link
G Tjp2 tight junction protein 2 decreases expression EXP Levofloxacin results in decreased expression of TJP2 mRNA CTD PMID:24136188 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
G Tkt transketolase decreases expression EXP Levofloxacin results in decreased expression of TKT mRNA CTD PMID:24136188 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tmem176b transmembrane protein 176B increases expression EXP Levofloxacin results in increased expression of TMEM176B mRNA CTD PMID:24136188 NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
JBrowse link
G Tmem38b transmembrane protein 38B increases expression EXP Levofloxacin results in increased expression of TMEM38B mRNA CTD PMID:24136188 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Levofloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Levofloxacin co-treated with TNF protein] results in increased expression of ICAM1 protein; [Levofloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA; [TNF protein co-treated with Levofloxacin] results in increased lipidation of MAP1LC3B protein; TNF protein promotes the reaction [Levofloxacin results in increased expression of MAP1LC3B protein]
[Levofloxacin co-treated with TNF protein] results in increased expression of BIRC2 mRNA; [Levofloxacin co-treated with TNF protein] results in increased expression of ICAM1 protein; [Levofloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA; [Levofloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA
CTD PMID:30876886 PMID:32035082 PMID:33609687 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Levofloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA CTD PMID:32035082 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Levofloxacin results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 decreases expression EXP Levofloxacin results in decreased expression of TNFRSF9 mRNA CTD PMID:24136188 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tob2 transducer of ERBB2, 2 increases expression EXP Levofloxacin results in increased expression of TOB2 mRNA CTD PMID:24136188 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Tpm3 tropomyosin 3 decreases expression EXP Levofloxacin results in decreased expression of TPM3 mRNA CTD PMID:24136188 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Levofloxacin results in increased expression of TSC22D3 mRNA CTD PMID:24136188 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tstd3 thiosulfate sulfurtransferase like domain containing 3 decreases expression EXP Levofloxacin results in decreased expression of TSTD3 mRNA CTD PMID:24136188 NCBI chr 5:35,294,652...35,304,101
Ensembl chr 5:35,294,645...35,304,101
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Levofloxacin results in decreased expression of TUBA1C mRNA CTD PMID:24136188 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Levofloxacin results in decreased expression of TUBB4B mRNA CTD PMID:24136188 NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Levofloxacin results in decreased expression of TUBB5 mRNA CTD PMID:24136188 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tubb6 tubulin, beta 6 class V decreases expression EXP Levofloxacin results in decreased expression of TUBB6 mRNA CTD PMID:24136188 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression EXP Levofloxacin results in increased expression of USP2 mRNA CTD PMID:24136188 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Levofloxacin results in increased expression of VCAM1 mRNA CTD PMID:24136188 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vim vimentin decreases expression EXP Levofloxacin results in decreased expression of VIM mRNA CTD PMID:24136188 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vmp1 vacuole membrane protein 1 increases expression EXP Levofloxacin results in increased expression of VMP1 mRNA CTD PMID:24136188 NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
JBrowse link
G Wasl WASP like actin nucleation promoting factor increases expression EXP Levofloxacin results in increased expression of WASL mRNA CTD PMID:24136188 NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression EXP Levofloxacin results in increased expression of WIPI1 mRNA CTD PMID:24136188 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Xpo1 exportin 1 decreases expression EXP Levofloxacin results in decreased expression of XPO1 mRNA CTD PMID:24136188 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
G Zfp354a zinc finger protein 354A increases expression EXP Levofloxacin results in increased expression of ZFP354A mRNA CTD PMID:24136188 NCBI chr10:35,396,242...35,408,065
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp446 zinc finger protein 446 increases expression EXP Levofloxacin results in increased expression of ZFP446 mRNA CTD PMID:24136188 NCBI chr 1:73,594,953...73,612,685 JBrowse link
ofloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Ofloxacin results in decreased activity of ABCB11 protein
Ofloxacin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 affects expression ISO Ofloxacin affects the expression of ARHGAP45 mRNA CTD PMID:25811541 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Ofloxacin results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] CTD PMID:11408986 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP3A4 protein results in increased metabolism of Theophylline] CTD PMID:11408986 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Ofloxacin results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Ofloxacin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA] CTD PMID:16148020 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO Ofloxacin results in decreased expression of ITGB4 protein CTD PMID:14687228 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects binding ISO Ofloxacin binds to KCNH2 protein CTD PMID:34058295 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression
ISO Ofloxacin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]
Ofloxacin results in decreased expression of MMP13 mRNA
CTD PMID:16148020 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP Ofloxacin results in increased expression of MMP3 mRNA CTD PMID:20688128 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Ofloxacin results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Ofloxacin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase decreases expression ISO Ofloxacin results in decreased expression of PHYH mRNA CTD PMID:15342952 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Ofloxacin results in increased expression of PLAUR mRNA CTD PMID:20688128 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Ofloxacin results in increased expression of PTGS2 mRNA CTD PMID:20688128 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Ofloxacin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO
EXP
Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:16928358 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc2a1 solute carrier family 2 member 1 affects localization
decreases expression
ISO Ofloxacin affects the localization of SLC2A1 mRNA
Ofloxacin results in decreased expression of SLC2A1 mRNA
CTD PMID:19022360 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP Ofloxacin results in increased expression of TNFRSF12A mRNA CTD PMID:20688128 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Ofloxacin CTD PMID:15769885 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Ofloxacin CTD PMID:15769885 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Ofloxacin CTD PMID:15769885 NCBI chr 9:88,696,981...88,808,465 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      chemical role 19341
        donor 18654
          Bronsted acid 18538
            oxoacid 18500
              carbon oxoacid 18381
                carboxylic acid 18376
                  monocarboxylic acid 17639
                    oxo monocarboxylic acid 6279
                      3-oxo monocarboxylic acid 228
                        (5S)-5-amino-3-oxohexanoic acid 0
                        (R)-2,4-dihydroxy-3-oxobutanoic acid 0
                        (S)-2,4-dihydroxy-3-oxobutanoic acid 0
                        (S)-2-acetyl-2-hydroxybutanoic acid 0
                        2-acetyllactic acid + 0
                        2-amino-3-oxobutanoic acid + 0
                        2-aminobenzoylacetic acid 0
                        2-ethyl-3-ketopentanoic acid 0
                        2-ethylacetoacetic acid 0
                        2-hydroxy-3-oxopropanoic acid 0
                        2-methyl-3-ketovaleric acid 0
                        2-methyl-3-oxopropanoic acid + 0
                        2-methylacetoacetic acid + 0
                        3-dehydro-D-gluconic acid 0
                        3-oxo fatty acid + 4
                        3-oxo-3-phenylpropionic acid + 0
                        3-oxo-3-ureidopropanoic acid 0
                        3-oxodocosanoic acid + 0
                        3-oxohexanoic acid + 0
                        3-oxoicosanoic acid + 0
                        3-oxotetracosanoic acid + 0
                        4'-O-demethylsordarin 0
                        6-acetamido-3-oxohexanoic acid 0
                        7-methyl-3-oxooct-6-enoic acid 0
                        7-methyl-3-oxooctanoic acid + 0
                        9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid + 28
                        bkos#9 + 0
                        feruloylacetic acid 0
                        ofloxacin + 203
                        sordaricin 0
                        vanilloylacetic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic group 18739
                              organic divalent group 18730
                                organodiyl group 18730
                                  carbonyl group 18678
                                    carbonyl compound 18678
                                      carboxylic acid 18376
                                        monocarboxylic acid 17639
                                          oxo monocarboxylic acid 6279
                                            3-oxo monocarboxylic acid 228
                                              (5S)-5-amino-3-oxohexanoic acid 0
                                              (R)-2,4-dihydroxy-3-oxobutanoic acid 0
                                              (S)-2,4-dihydroxy-3-oxobutanoic acid 0
                                              (S)-2-acetyl-2-hydroxybutanoic acid 0
                                              2-acetyllactic acid + 0
                                              2-amino-3-oxobutanoic acid + 0
                                              2-aminobenzoylacetic acid 0
                                              2-ethyl-3-ketopentanoic acid 0
                                              2-ethylacetoacetic acid 0
                                              2-hydroxy-3-oxopropanoic acid 0
                                              2-methyl-3-ketovaleric acid 0
                                              2-methyl-3-oxopropanoic acid + 0
                                              2-methylacetoacetic acid + 0
                                              3-dehydro-D-gluconic acid 0
                                              3-oxo fatty acid + 4
                                              3-oxo-3-phenylpropionic acid + 0
                                              3-oxo-3-ureidopropanoic acid 0
                                              3-oxodocosanoic acid + 0
                                              3-oxohexanoic acid + 0
                                              3-oxoicosanoic acid + 0
                                              3-oxotetracosanoic acid + 0
                                              4'-O-demethylsordarin 0
                                              6-acetamido-3-oxohexanoic acid 0
                                              7-methyl-3-oxooct-6-enoic acid 0
                                              7-methyl-3-oxooctanoic acid + 0
                                              9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid + 28
                                              bkos#9 + 0
                                              feruloylacetic acid 0
                                              ofloxacin + 203
                                              sordaricin 0
                                              vanilloylacetic acid + 0
paths to the root