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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluoroalcohol
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Accession:CHEBI:47852 term browser browse the term


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2,2,2-trifluoroethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO Trifluoroethanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] CTD PMID:10683198 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gh1 growth hormone 1 affects folding ISO Trifluoroethanol affects the folding of GH1 protein CTD PMID:11064379 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Trifluoroethanol promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein] CTD PMID:10683198 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Prnp prion protein affects folding ISO Trifluoroethanol affects the folding of PRNP protein modified form CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP11A1 mRNA; 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP11A1 protein CTD PMID:20615422 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression ISO 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP11B2 mRNA; 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP11B2 protein CTD PMID:20615422 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP17A1 mRNA; 1H,1H,2H,2H-perfluorodecanol results in decreased expression of CYP17A1 protein CTD PMID:20615422 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO 1H,1H,2H,2H-perfluorodecanol results in decreased expression of ERBB2 mRNA CTD PMID:16393665 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Esr1 estrogen receptor 1 increases activity
increases expression
multiple interactions
ISO 1H,1H,2H,2H-perfluorodecanol results in increased activity of ESR1 protein
1H,1H,2H,2H-perfluorodecanol results in increased expression of ESR1 mRNA
1H,1H,2H,2H-perfluorodecanol promotes the reaction [ESR1 protein binds to NCOA2 protein]
CTD PMID:16393665 PMID:17603182 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO 1H,1H,2H,2H-perfluorodecanol promotes the reaction [ESR2 protein binds to NCOA2 protein]
1H,1H,2H,2H-perfluorodecanol results in increased activity of ESR2 protein
CTD PMID:17603182 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 1H,1H,2H,2H-perfluorodecanol promotes the reaction [ESR1 protein binds to NCOA2 protein]; 1H,1H,2H,2H-perfluorodecanol promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:17603182 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO 1H,1H,2H,2H-perfluorodecanol results in increased expression of PDZK1 mRNA CTD PMID:16393665 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
JBrowse link
G Pgr progesterone receptor increases expression ISO 1H,1H,2H,2H-perfluorodecanol results in increased expression of PGR mRNA CTD PMID:16393665 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases expression EXP 1H,1H,2H,2H-perfluorodecanol results in increased expression of SLC22A7 mRNA CTD PMID:21530637 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO 1H,1H,2H,2H-perfluorodecanol results in decreased expression of STAR mRNA; 1H,1H,2H,2H-perfluorodecanol results in decreased expression of STAR protein CTD PMID:20615422 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 1H,1H,2H,2H-perfluorodecanol results in increased expression of TFF1 mRNA CTD PMID:16393665 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      molecular entity 19819
        main group molecular entity 19716
          p-block molecular entity 19716
            halogen molecular entity 18171
              fluorine molecular entity 11590
                organofluorine compound 11008
                  fluoroalcohol 18
                    2,2,2-trifluoroethanol 6
                    fluorotelomer alcohol + 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      p-block molecular entity 19716
                        carbon group molecular entity 19640
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organohalogen compound 17920
                                organofluorine compound 11008
                                  fluoroalcohol 18
                                    2,2,2-trifluoroethanol 6
                                    fluorotelomer alcohol + 12
paths to the root