sulforaphane - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	sulforaphane	go back to main search page
Accession:	CHEBI:47807	browse the term
Definition:	An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Synonyms:	exact_synonym:	4-isothiocyanatobutyl methyl sulfoxide
	related_synonym:	1-Isothiocyanato-4-(methylsulfinyl)butane; Formula=C6H11NOS2; InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3; InChIKey=SUVMJBTUFCVSAD-UHFFFAOYSA-N; SMILES=N(=C=S)CCCCS(=O)C; Sulforafan
	xref:	CAS:4478-93-7; HMDB:HMDB0005792; LINCS:LSM-4919
	xref_mesh:	MESH:C016766
	xref:	PMID:16442570; PMID:17134937; PMID:18090122; Patent:CA2839972; Patent:CN103229711; Patent:US2013323225; Patent:WO2013179056; Patent:WO2013179057; Reaxys:1723237; Wikipedia:Sulforaphane

show annotations for term's descendants Sort by:
Rat (1834) Mouse (1857) Human (1907) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (11) Green Monkey (0) Naked Mole-rat (0) All
Genes (1834)

sulforaphane

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 6430548M08 gene like

decreases expression

sulforaphane results in decreased expression of KIAA0513 mRNA

NCBI chr19:65,076,626...65,125,185
Ensembl chr19:48,198,209...48,216,575

G

APOBEC1 complementation factor

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of A1CF mRNA

NCBI chr 1:239,149,436...239,242,460
Ensembl chr 1:229,736,106...229,824,354

G

alpha-2-macroglobulin

decreases expression

sulforaphane results in decreased expression of A2M mRNA

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786

G

alpha 1,4-galactosyltransferase

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of A4GALT mRNA

NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:114,368,276...114,396,071

G

aminoadipate-semialdehyde synthase

decreases expression

sulforaphane results in decreased expression of AASS mRNA

NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:51,606,462...51,663,136

G

apoptosis-associated tyrosine kinase

decreases expression

sulforaphane results in decreased expression of AATK mRNA

NCBI chr10:105,789,171...105,825,634
Ensembl chr10:105,291,585...105,327,112

G

ATP binding cassette subfamily A member 1

multiple interactions

sulforaphane inhibits the reaction [fenamidone results in increased expression of ABCA1 mRNA]

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 7

decreases expression

sulforaphane results in decreased expression of ABCA7 mRNA

NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:9,691,449...9,711,425

G

ATP binding cassette subfamily B member 10

decreases expression

sulforaphane results in decreased expression of ABCB10 mRNA

NCBI chr19:68,850,108...68,881,689
Ensembl chr19:51,952,681...51,982,753

G

ATP binding cassette subfamily B member 1A

multiple interactions
decreases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ABCB1A mRNA; sulforaphane inhibits the reaction [Genistein results in increased expression of ABCB1A mRNA]
sulforaphane results in decreased expression of ABCB1 mRNA
sulforaphane inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]

PMID:25450479 PMID:26775663 PMID:32185415

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 6

increases expression

sulforaphane results in increased expression of ABCB6 mRNA

NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:76,668,554...76,676,924

G

ATP binding cassette subfamily C member 1

multiple interactions
increases expression

NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of ABCC1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of ABCC1 protein]; sulforaphane results in increased expression of and results in increased activity of ABCC1 protein

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily C member 2

increases expression

sulforaphane results in increased expression of ABCC2 mRNA; sulforaphane results in increased expression of ABCC2 protein

PMID:11264000 PMID:15896333 PMID:25841332 PMID:31838189 PMID:34767876

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

sulforaphane results in increased expression of ABCC3 mRNA

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

sulforaphane results in increased expression of ABCC4 mRNA; sulforaphane results in increased expression of ABCC4 protein

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily G member 5

decreases expression

sulforaphane results in decreased expression of ABCG5 mRNA

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563

G

abhydrolase domain containing 3, phospholipase

increases expression

sulforaphane results in increased expression of ABHD3 mRNA

NCBI chr18:1,996,010...2,051,311
Ensembl chr18:1,720,718...1,803,428

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

sulforaphane results in increased expression of ABHD4 mRNA

PMID:26833863 PMID:31838189

NCBI chr15:31,674,090...31,686,051
Ensembl chr15:27,704,113...27,716,966

G

actin binding LIM protein family, member 2

decreases expression

sulforaphane results in decreased expression of ABLIM2 mRNA

NCBI chr14:79,090,046...79,214,986
Ensembl chr14:74,866,281...74,990,334

G

actin binding LIM protein family, member 3

increases expression

sulforaphane results in increased expression of ABLIM3 mRNA

NCBI chr18:57,527,917...57,646,936
Ensembl chr18:55,257,583...55,376,380

G

acetyl-CoA acyltransferase 2

increases expression

sulforaphane results in increased expression of ACAA2 mRNA

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249

G

acyl-CoA dehydrogenase, long chain

increases expression

sulforaphane results in increased expression of ACADL mRNA

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase medium chain

increases expression

sulforaphane results in increased expression of ACADM mRNA

NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147

G

acyl-CoA dehydrogenase, very long chain

increases expression

sulforaphane results in increased expression of ACADVL mRNA

NCBI chr10:55,231,558...55,236,786
Ensembl chr10:54,732,469...54,738,075

G

acyl-CoA binding domain containing 4

decreases expression

sulforaphane results in decreased expression of ACBD4 mRNA

NCBI chr10:88,548,146...88,558,588
Ensembl chr10:88,048,108...88,058,500

G

alkaline ceramidase 2

decreases expression

sulforaphane results in decreased expression of ACER2 mRNA

NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:101,391,885...101,442,614

G

atypical chemokine receptor 1

increases expression

sulforaphane results in increased expression of DARC mRNA

NCBI chr13:88,314,735...88,316,354
Ensembl chr13:85,782,398...85,783,983

G

atypical chemokine receptor 2

decreases expression

sulforaphane results in decreased expression of ACKR2 mRNA

NCBI chr 8:130,438,703...130,451,106
Ensembl chr 8:121,561,211...121,573,582

G

ATP citrate lyase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320

G

aconitase 2

increases expression

sulforaphane results in increased expression of ACO2 mRNA

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACOT1 mRNA

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACOT2 mRNA

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA thioesterase 4

decreases expression

sulforaphane results in decreased expression of ACOT4 mRNA

NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:103,668,753...103,673,917

G

acid phosphatase 5, tartrate resistant

increases expression

sulforaphane results in increased expression of ACP5 mRNA

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:20,663,985...20,667,929

G

acyl-CoA synthetase family member 2

decreases expression

sulforaphane results in decreased expression of ACSF2 mRNA

NCBI chr10:80,001,389...80,043,796
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression

sulforaphane results in increased expression of ACSL1 mRNA

PMID:26833863 PMID:30529165 PMID:31838189

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase medium-chain family member 3

decreases expression

sulforaphane results in decreased expression of ACSM3 mRNA

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:174,133,288...174,160,184

G

actin alpha 2, smooth muscle

affects binding
multiple interactions

ACTA2 protein binds to sulforaphane
sulforaphane inhibits the reaction [fenamidone results in increased expression of ACTA2 mRNA]

PMID:21838287 PMID:27029645

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

actin, beta

affects binding

ACTB protein binds to sulforaphane

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877

G

actin, alpha, cardiac muscle 1

increases expression
decreases expression

sulforaphane results in increased expression of ACTC1 mRNA
sulforaphane results in decreased expression of ACTC1 mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:100,811,987...100,817,523

G

actin gamma 2, smooth muscle

increases expression

sulforaphane results in increased expression of ACTG2 mRNA

NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:116,021,832...116,046,465

G

actin related protein 1A

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ACTR1A mRNA

NCBI chr 1:255,179,241...255,199,009
Ensembl chr 1:245,237,826...245,256,495

G

adenosine deaminase

decreases expression

sulforaphane results in decreased expression of ADA mRNA

NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 17

increases expression

sulforaphane results in increased expression of ADAM17 mRNA

NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639

G

ADAM metallopeptidase domain 19

decreases expression
multiple interactions

sulforaphane results in decreased expression of ADAM19 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAM19 mRNA

NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase domain 21

increases expression

sulforaphane results in increased expression of ADAM21 mRNA

NCBI chr16:43,351,935...43,361,020
Ensembl chr16:36,618,860...36,628,008

G

ADAM metallopeptidase domain 22

decreases expression

sulforaphane results in decreased expression of ADAM22 mRNA

NCBI chr 4:26,670,984...26,925,843
Ensembl chr 4:25,715,990...25,964,962

G

ADAM metallopeptidase domain 33

decreases expression

sulforaphane results in decreased expression of ADAM33 mRNA

NCBI chr 3:138,715,428...138,736,392
Ensembl chr 3:118,271,029...118,283,461

G

ADAM metallopeptidase domain 8

increases expression

sulforaphane results in increased expression of ADAM8 mRNA

NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:194,770,060...194,788,801

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

multiple interactions
decreases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAMTS15 mRNA
sulforaphane results in decreased expression of ADAMTS15 mRNA

PMID:30529165 PMID:31838189

NCBI chr 8:37,566,064...37,589,446
Ensembl chr 8:29,307,865...29,331,249

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

decreases expression

sulforaphane results in decreased expression of ADAMTS5 mRNA

NCBI chr11:38,486,945...38,533,516
Ensembl chr11:25,000,637...25,047,205

G

ADAM metallopeptidase with thrombospondin type 1 motif, 6

decreases expression

sulforaphane results in decreased expression of ADAMTS6 mRNA

NCBI chr 2:37,155,260...37,367,077
Ensembl chr 2:35,421,510...35,633,298

G

ADAMTS-like 4

decreases expression

sulforaphane results in decreased expression of ADAMTSL4 mRNA

NCBI chr 2:185,924,582...185,936,039
Ensembl chr 2:183,235,646...183,246,848

G

adenylate cyclase 7

decreases expression

sulforaphane results in decreased expression of ADCY7 mRNA

NCBI chr19:34,913,154...34,972,366
Ensembl chr19:18,740,875...18,776,311

G

adenylate cyclase 8

decreases expression

sulforaphane results in decreased expression of ADCY8 mRNA

NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor A2

decreases expression

sulforaphane results in decreased expression of ADGRA2 mRNA

NCBI chr16:71,635,814...71,674,275
Ensembl chr16:64,933,315...64,971,483

G

adhesion G protein-coupled receptor D1

decreases expression

sulforaphane results in decreased expression of ADGRD1 mRNA

NCBI chr12:33,124,981...33,239,778
Ensembl chr12:27,488,908...27,603,696

G

adhesion G protein-coupled receptor E4

increases expression

sulforaphane results in increased expression of ADGRE4P mRNA

NCBI chr 9:10,085,258...10,240,346
Ensembl chr 9:9,760,355...9,900,760

G

adhesion G protein-coupled receptor E5

increases expression

sulforaphane results in increased expression of ADGRE5 mRNA

NCBI chr19:41,302,687...41,332,183
Ensembl chr19:24,398,689...24,418,638

G

adhesion G protein-coupled receptor G1

decreases expression

sulforaphane results in decreased expression of ADGRG1 mRNA

NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G3

increases expression

sulforaphane results in increased expression of ADGRG3 mRNA

NCBI chr19:9,978,450...10,007,145
Ensembl chr19:9,972,430...10,001,123

G

adhesion G protein-coupled receptor L1

decreases expression

sulforaphane results in decreased expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:24,204,360...24,244,139

G

adhesion G protein-coupled receptor L3

decreases expression

sulforaphane results in decreased expression of ADGRL3 mRNA

NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,368,277...27,105,860

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADH7 mRNA

NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:226,741,788...226,763,182

G

adipogenin

increases expression

sulforaphane results in increased expression of ADIG mRNA

NCBI chr 3:167,574,963...167,580,296
Ensembl chr 3:147,154,097...147,160,490
Ensembl chr 3:147,154,097...147,160,490

G

adiponectin, C1Q and collagen domain containing

increases expression

sulforaphane results in increased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

adrenomedullin

increases expression

sulforaphane results in increased expression of ADM mRNA

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654

G

activity-dependent neuroprotector homeobox

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ADNP mRNA

NCBI chr 3:177,310,258...177,340,379
Ensembl chr 3:156,891,381...156,917,312

G

adenosine A2a receptor

increases expression

sulforaphane results in increased expression of ADORA2A mRNA

NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386

G

adenosine A2B receptor

increases expression

sulforaphane results in increased expression of ADORA2B mRNA

NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772

G

adenosine A3 receptor

increases expression

sulforaphane results in increased expression of ADORA3 mRNA

NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:193,388,713...193,392,357

G

adrenoceptor beta 1

decreases expression
increases expression

sulforaphane results in decreased expression of ADRB1 mRNA
sulforaphane results in increased expression of ADRB1 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:255,771,597...255,807,259

G

advanced glycosylation end product-specific receptor

multiple interactions

sulforaphane reverses the reaction [ethanol decreases expression of AGER protein in cultured alveolar macrophage membrane]

RGD

NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078

G

ArfGAP with FG repeats 2

decreases expression

sulforaphane results in decreased expression of AGFG2 mRNA

NCBI chr12:24,649,008...24,692,069
Ensembl chr12:19,012,258...19,048,421

G

anterior gradient 3, protein disulphide isomerase family member

increases expression

sulforaphane results in increased expression of AGR3 mRNA

NCBI chr 6:58,370,701...58,393,944
Ensembl chr 6:52,643,391...52,666,638

G

angiotensinogen

multiple interactions

NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein modified form]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]
brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in decreased activity of CAT protein]]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of and results in decreased activity of NFE2L2 protein]]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased abundance of Glutathione Disulfide]]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP3 protein]]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP9 protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of and results in decreased activity of NFE2L2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased abundance of Glutathione Disulfide]; sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP9 protein]

PMID:29353218 PMID:31957488

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor-associated protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of AGTRAP mRNA

NCBI chr 5:163,790,565...163,802,174
Ensembl chr 5:158,508,749...158,519,036

G

aryl hydrocarbon receptor

multiple interactions
affects binding

AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; sulforaphane affects the reaction [anthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [1,2,5,6-dibenzanthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein]
sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]
[sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein]] promotes the reaction [sulforaphane analog binds to AHR protein]; sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein]
sulforaphane binds to AHR protein

PMID:19202560 PMID:19362136 PMID:21177068 PMID:22643862 PMID:23566952 More...

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

apoptosis inducing factor, mitochondria associated 1

increases expression

sulforaphane results in increased expression of AIFM1 protein

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:127,650,226...127,689,256

G

adenylate kinase 6

increases expression

sulforaphane results in increased expression of AK6 mRNA

NCBI chr 2:33,528,388...33,540,445
Ensembl chr 2:31,794,519...31,806,371
Ensembl chr20:31,794,519...31,806,371

G

adenylate kinase 9

increases expression

sulforaphane results in increased expression of AK9 mRNA

NCBI chr20:46,307,100...46,523,537
Ensembl chr20:44,724,496...44,941,136

G

A-kinase anchoring protein 5

decreases expression

sulforaphane results in decreased expression of AKAP5 mRNA

NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:95,051,537...95,061,578

G

akirin 2

increases expression

sulforaphane results in increased expression of AKIRIN2 mRNA

NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:49,108,220...49,122,568

G

aldo-keto reductase family 1 member B10

increases expression

sulforaphane results in increased expression of AKR1B10 mRNA

PMID:24383545 PMID:31518892 PMID:31838189

NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

increases expression
multiple interactions

sulforaphane results in increased expression of AKR1C1 mRNA
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AKR1C1 mRNA]

PMID:24383545 PMID:25841332 PMID:31518892 PMID:31746589

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

sulforaphane results in increased expression of AKR1C2 mRNA

PMID:24383545 PMID:31746589

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764

G

aldo-keto reductase family 1, member C3

increases expression

sulforaphane results in increased expression of AKR1C3 mRNA; sulforaphane results in increased expression of AKR1C3 protein

PMID:24383545 PMID:31746589

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 1

multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression

NGF protein inhibits the reaction [sulforaphane results in decreased phosphorylation of AKT1 protein]; sulforaphane results in increased phosphorylation of and results in increased activity of AKT1 protein
[dibenzoylmethane co-treated with sulforaphane] results in decreased phosphorylation of AKT1 protein
sulforaphane results in increased phosphorylation of AKT1 protein
sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT mRNA]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT protein]
sulforaphane results in decreased expression of AKT mRNA

PMID:15896333 PMID:17942926 PMID:29407470 PMID:30965051 PMID:37906532

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

albumin

multiple interactions

sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CDK6 protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IFNG protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene]

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836

G

activated leukocyte cell adhesion molecule

decreases expression

sulforaphane results in decreased expression of ALCAM mRNA

NCBI chr11:61,804,932...62,005,250
Ensembl chr11:48,336,169...48,537,954

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions
decreases expression
affects binding

sulforaphane promotes the reaction [Gemcitabine results in decreased expression of ALDH1A1 protein]
sulforaphane results in decreased expression of ALDH1A1 protein
ALDH1A1 protein binds to sulforaphane

PMID:20940707 PMID:21838287

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A3

decreases expression

sulforaphane results in decreased expression of ALDH1A3 mRNA

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 1 family, member L2

decreases expression

sulforaphane results in decreased expression of ALDH1L2 mRNA

NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 2 family member

increases expression
multiple interactions

sulforaphane results in increased expression of ALDH2 mRNA; sulforaphane results in increased expression of ALDH2 protein
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of ALDH2 protein]

PMID:31838189 PMID:35227738

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A2

increases expression

sulforaphane results in increased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

sulforaphane results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:151,830,701...151,925,345

G

arachidonate 5-lipoxygenase activating protein

increases expression

sulforaphane results in increased expression of ALOX5AP mRNA

NCBI chr12:10,785,254...10,809,295
Ensembl chr12:5,748,944...5,772,986

G

alkaline phosphatase, germ cell

decreases expression

sulforaphane results in decreased expression of ALPG mRNA

NCBI chr 9:95,187,995...95,205,127
Ensembl chr 9:87,753,648...87,757,836

G

alkaline phosphatase, intestinal

decreases expression

sulforaphane results in decreased expression of ALPI mRNA

NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:87,773,411...87,776,877

G

alkaline phosphatase, placental

increases expression
decreases expression

sulforaphane results in increased expression of ALPP mRNA
sulforaphane results in decreased expression of ALPP mRNA

PMID:26833863 PMID:31838189

NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:87,765,860...87,768,606

G

anti-Mullerian hormone

increases expression

sulforaphane results in increased expression of AMH mRNA

NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:8,906,836...8,909,282

G

angiomotin-like 1

decreases expression

sulforaphane results in decreased expression of AMOTL1 mRNA

NCBI chr 8:19,630,139...19,749,027
Ensembl chr 8:11,353,674...11,467,573

G

anaphase promoting complex subunit 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ANAPC4 mRNA

NCBI chr14:62,338,798...62,370,572
Ensembl chr14:58,125,995...58,157,770

G

angiogenin

decreases expression

sulforaphane results in decreased expression of ANG mRNA

NCBI chr15:26,786,233...26,796,883

G

angiopoietin-like 4

increases expression

sulforaphane results in increased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin 2

increases expression

sulforaphane results in increased expression of ANK2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:215,379,680...215,862,923

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

sulforaphane results in decreased expression of ANKH mRNA

NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:78,153,026...78,280,187

G

ankyrin repeat and KH domain containing 1

increases methylation

sulforaphane results in increased methylation of ANKHD1 gene

NCBI chr18:28,436,296...28,534,954
Ensembl chr18:28,162,311...28,268,024

G

ankyrin repeat domain 2

decreases expression

sulforaphane results in decreased expression of ANKRD2 mRNA

NCBI chr 1:250,796,419...250,805,867
Ensembl chr 1:240,847,072...240,856,566

G

ankyrin repeat domain 22

increases expression

sulforaphane results in increased expression of ANKRD22 mRNA

NCBI chr 1:241,052,235...241,083,737
Ensembl chr 1:231,639,314...231,670,381

G

ankyrin repeat domain 29

decreases expression

sulforaphane results in decreased expression of ANKRD29 mRNA

NCBI chr18:3,436,301...3,494,292
Ensembl chr18:3,436,303...3,494,296

G

ankyrin repeat domain 49

decreases expression

sulforaphane results in decreased expression of ANKRD49 mRNA

NCBI chr 8:19,908,968...19,913,656
Ensembl chr 8:11,627,518...11,632,207

G

anoctamin 2

decreases expression

sulforaphane results in decreased expression of ANO2 mRNA

NCBI chr 4:160,200,471...160,541,830
Ensembl chr 4:158,496,014...158,855,651

G

anoctamin 9

decreases expression

sulforaphane results in decreased expression of ANO9 mRNA

NCBI chr 1:205,638,571...205,659,780
Ensembl chr 1:196,197,341...196,229,900

G

adenine nucleotide translocase lysine methyltransferase

decreases expression

sulforaphane results in decreased expression of ANTKMT mRNA

NCBI chr10:15,316,797...15,320,950
Ensembl chr10:14,812,269...14,814,193

G

ANTXR cell adhesion molecule 2

increases expression

sulforaphane results in increased expression of ANTXR2 mRNA

NCBI chr14:11,845,774...11,986,166
Ensembl chr14:11,541,772...11,682,094

G

annexin A1

increases expression

sulforaphane results in increased expression of ANXA1 mRNA

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343

G

annexin A8

increases expression
decreases expression

sulforaphane results in increased expression of ANXA8 mRNA
sulforaphane results in decreased expression of ANXA8 mRNA

PMID:30529165 PMID:31838189

NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,397,113...9,412,043

G

amine oxidase, copper containing 2, pseudogene 1

increases expression

sulforaphane results in increased expression of AOC2 mRNA

NCBI chr10:86,767,268...86,768,734

G

adaptor related protein complex 3 subunit mu 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of AP3M1 mRNA

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,246,926...3,264,844

G

amyloid beta precursor protein binding family B member 1 interacting protein

decreases expression

sulforaphane results in decreased expression of APBB1IP mRNA

NCBI chr17:89,849,474...89,941,099
Ensembl chr17:84,982,243...85,033,010

G

APC down-regulated 1

decreases expression

sulforaphane results in decreased expression of APCDD1 mRNA

NCBI chr18:58,655,696...58,686,359
Ensembl chr18:56,385,264...56,416,070

G

amyloid beta precursor like protein 1

decreases expression

sulforaphane results in decreased expression of APLP1 mRNA

NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:85,696,882...85,707,155

G

apolipoprotein L7a like 1

increases expression

sulforaphane results in increased expression of APOL7A mRNA

Ensembl chr 7:109,131,064...109,147,649

G

apolipoprotein O

increases expression

sulforaphane results in increased expression of APOO mRNA

NCBI chr X:63,151,736...63,256,696
Ensembl chr X:59,158,049...59,262,940

G

aquaporin 3 (Gill blood group)

decreases expression

sulforaphane results in decreased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 4

increases expression

sulforaphane results in increased expression of AQP4 mRNA

NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,507,903...6,524,856

G

androgen receptor

multiple interactions
increases expression

benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulforaphane results in decreased expression of AR protein]; HDAC6 protein inhibits the reaction [sulforaphane results in decreased expression of AR protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AR protein]; sulforaphane inhibits the reaction [AR protein binds to ERG enhancer]; sulforaphane inhibits the reaction [AR protein binds to KLK3 enhancer]; sulforaphane inhibits the reaction [HSP90AA1 protein binds to AR protein]; sulforaphane results in increased degradation of and results in decreased expression of and results in decreased activity of AR protein

PMID:19805354 PMID:35227738

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

amphiregulin

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of AREG mRNA

NCBI chr14:17,256,384...17,265,641
Ensembl chr14:16,972,187...16,981,535

G

ARFGEF family member 3

decreases expression

sulforaphane results in decreased expression of ARFGEF3 mRNA

NCBI chr 1:15,058,574...15,223,742
Ensembl chr 1:13,244,830...13,404,084

G

arginase 2

decreases expression

sulforaphane results in decreased expression of ARG2 mRNA

NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 20

decreases expression

sulforaphane results in decreased expression of ARHGAP20 mRNA

NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:52,074,158...52,155,739

G

Rho GTPase activating protein 26

increases expression

sulforaphane results in increased expression of ARHGAP26 mRNA

NCBI chr18:30,702,602...31,489,047
Ensembl chr18:30,838,671...31,235,194

G

Rho GTPase activating protein 28

decreases expression

sulforaphane results in decreased expression of ARHGAP28 mRNA

NCBI chr 9:115,277,849...115,444,789
Ensembl chr 9:107,833,330...107,998,000

G

Rho GTPase activating protein 31

decreases expression

sulforaphane results in decreased expression of ARHGAP31 mRNA

NCBI chr11:75,544,176...75,657,087
Ensembl chr11:62,038,635...62,151,564

G

Rho GDP dissociation inhibitor beta

decreases expression

sulforaphane results in decreased expression of ARHGDIB mRNA

NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:169,822,952...169,841,658

G

Rho guanine nucleotide exchange factor 10 like

increases expression

sulforaphane results in increased expression of ARHGEF10L mRNA

NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538

G

Rho guanine nucleotide exchange factor 26

decreases expression

sulforaphane results in decreased expression of ARHGEF26 mRNA

NCBI chr 2:148,889,405...149,000,538
Ensembl chr 2:146,739,631...146,850,819

G

Rho guanine nucleotide exchange factor 39

increases expression

sulforaphane results in increased expression of ARHGEF39 mRNA

NCBI chr 5:62,548,300...62,551,870
Ensembl chr 5:57,752,509...57,756,109

G

Cdc42 guanine nucleotide exchange factor 9

decreases expression

sulforaphane results in decreased expression of ARHGEF9 mRNA

NCBI chr X:63,929,168...64,087,267
Ensembl chr X:59,920,870...60,077,513

G

AT-rich interaction domain 3A

increases expression

sulforaphane results in increased expression of ARID3A mRNA

NCBI chr 7:10,403,161...10,431,551
Ensembl chr 7:9,755,294...9,780,599

G

AT-rich interaction domain 5B

decreases expression

sulforaphane results in decreased expression of ARID5B mRNA

NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,307,731...20,487,433

G

arylsulfatase family, member J

increases expression

sulforaphane results in increased expression of ARSJ mRNA

NCBI chr 2:217,449,147...217,529,142
Ensembl chr 2:214,774,654...214,854,612

G

ADP-ribosyltransferase 3

increases expression

sulforaphane results in increased expression of ART3 mRNA

NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,637,237...15,665,407

G

ankyrin repeat and SOCS box-containing 2

increases expression

sulforaphane results in increased expression of ASB2 mRNA

NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:122,474,756...122,510,854

G

ankyrin repeat and SOCS box-containing 9

decreases expression

sulforaphane results in decreased expression of ASB9 mRNA

NCBI chr X:33,588,484...33,633,285
Ensembl chr X:29,956,576...30,001,105

G

anti-silencing function 1A histone chaperone

increases expression

sulforaphane results in increased expression of ASF1A mRNA

NCBI chr20:33,436,632...33,451,478
Ensembl chr20:32,893,573...32,908,808

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

sulforaphane results in increased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423

G

aspartate-beta-hydroxylase

increases expression

sulforaphane results in increased expression of ASPH mRNA

NCBI chr 5:27,398,933...27,611,519
Ensembl chr 5:22,603,486...22,813,876

G

asporin

decreases expression

sulforaphane results in decreased expression of ASPN mRNA

NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,080,639...15,104,041

G

argininosuccinate synthase 1

decreases expression

sulforaphane results in decreased expression of ASS1 mRNA

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 4

multiple interactions
increases expression

sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
sulforaphane results in increased expression of ATF4 protein

PMID:24967692 PMID:37385402

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446

G

autophagy related 12

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATG12 mRNA

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418

G

atonal bHLH transcription factor 8

decreases expression

sulforaphane results in decreased expression of ATOH8 mRNA

NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:104,259,992...104,292,168

G

ATPase cation transporting 13A2

increases expression

sulforaphane results in increased expression of ATP13A2 mRNA

NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:153,292,751...153,312,139

G

ATPase Na+/K+ transporting subunit alpha 3

decreases expression

sulforaphane results in decreased expression of ATP1A3 mRNA

NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:80,572,796...80,601,918

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases expression

sulforaphane results in increased expression of ATP2A2 mRNA

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:34,072,683...34,122,101

G

ATPase plasma membrane Ca2+ transporting 4

decreases expression

sulforaphane results in decreased expression of ATP2B4 mRNA

NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246

G

ATP synthase F1 subunit beta

affects binding

ATP5F1B protein binds to sulforaphane

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:515,460...567,273

G

ATP synthase membrane subunit c locus 1

increases expression

sulforaphane results in increased expression of ATP5MC1 mRNA

NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase membrane subunit e

increases expression

sulforaphane results in increased expression of ATP5ME mRNA

NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,319,868...1,321,013

G

ATPase H+ transporting V0 subunit D2

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATP6V0D2 mRNA
sulforaphane results in decreased expression of ATP6V0D2 mRNA

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:33,336,264...33,385,354

G

ataxin 10

decreases expression

sulforaphane results in decreased expression of ATXN10 mRNA

NCBI chr 7:118,321,516...118,444,967
Ensembl chr 7:116,441,613...116,565,087

G

aurora kinase A

increases expression

sulforaphane results in increased expression of AURKA mRNA

NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390

G

Beta-1,3-galactosyltransferase 4

decreases expression

sulforaphane results in decreased expression of B3GALT4 mRNA

NCBI chr20:4,937,974...4,939,549
Ensembl chr20:4,931,768...4,938,315

G

beta-1,3-glucuronyltransferase 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of B3GAT3 mRNA

NCBI chr 1:215,246,453...215,253,033
Ensembl chr 1:205,817,378...205,837,807

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

increases expression

sulforaphane results in increased expression of B3GNT5 mRNA

NCBI chr11:94,645,480...94,657,584
Ensembl chr11:81,140,599...81,156,166

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

increases expression

sulforaphane results in increased expression of B4GALNT1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 7:64,873,909...64,881,512
Ensembl chr 7:62,988,930...62,996,190

G

beta-1,4-galactosyltransferase 1

increases expression

sulforaphane results in increased expression of B4GALT1 mRNA

NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:55,935,615...55,982,461

G

beta-1,4-galactosyltransferase 6

increases expression

sulforaphane results in increased expression of B4GALT6 mRNA

NCBI chr18:12,233,350...12,290,204
Ensembl chr18:11,958,390...12,015,247

G

BTB domain and CNC homolog 1

increases expression

sulforaphane results in increased expression of BACH1 mRNA; sulforaphane results in increased expression of BACH1 protein

NCBI chr11:40,425,721...40,461,118
Ensembl chr11:26,939,480...26,972,447

G

BCL2-associated agonist of cell death

decreases expression

sulforaphane results in decreased expression of BAD mRNA

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823

G

BAG cochaperone 1

decreases expression

sulforaphane results in decreased expression of BAG1 mRNA

NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:56,068,494...56,081,075

G

BAG cochaperone 3

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BAG3 mRNA
sulforaphane results in increased expression of BAG3 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858

G

Btg3 associated nuclear protein

decreases expression

sulforaphane results in decreased expression of BANP mRNA

NCBI chr19:66,916,417...66,994,286
Ensembl chr19:50,007,881...50,082,738

G

BRCA1 associated deubiquitinase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BAP1 mRNA

NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,446,709...6,455,535

G

brain abundant, membrane attached signal protein 1

increases expression

sulforaphane results in increased expression of BASP1 mRNA

NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:75,816,122...75,864,043

G

basic leucine zipper ATF-like transcription factor 3

increases expression

sulforaphane results in increased expression of BATF3 mRNA

NCBI chr13:105,220,782...105,232,365
Ensembl chr13:102,689,657...102,701,139

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

sulforaphane results in increased expression of BAX protein
sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]
sulforaphane results in increased expression of BAX mRNA; sulforaphane results in increased expression of BAX protein

PMID:17942926 PMID:24967692 PMID:26833863 PMID:27878984 PMID:27993529

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

multiple interactions
increases expression

sulforaphane inhibits the reaction [ochratoxin A results in increased expression of BBC3 mRNA]
sulforaphane results in increased expression of BBC3 mRNA; sulforaphane results in increased expression of BBC3 protein

PMID:27878984 PMID:28710020 PMID:35724838

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509

G

basal cell adhesion molecule (Lutheran blood group)

decreases expression

sulforaphane results in decreased expression of BCAM mRNA

NCBI chr 1:88,542,971...88,557,358
Ensembl chr 1:79,415,017...79,429,403

G

butyrylcholinesterase

increases expression

sulforaphane results in increased expression of BCHE mRNA

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148

G

branched chain keto acid dehydrogenase E1 subunit alpha

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BCKDHA mRNA

NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:81,138,947...81,167,862

G

BCL10, immune signaling adaptor

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BCL10 mRNA

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523

G

BCL2, apoptosis regulator

multiple interactions
increases expression
decreases expression

[Eugenol results in increased activity of sulforaphane] which results in decreased expression of BCL2; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of BCL2
sulforaphane inhibits the reaction [Ethanol results in decreased expression of BCL2 mRNA]; sulforaphane inhibits the reaction [Ethanol results in decreased expression of BCL2 protein]
sulforaphane results in increased expression of BCL2 mRNA; sulforaphane results in increased expression of BCL2 protein
sulforaphane results in decreased expression of BCL2 mRNA; sulforaphane results in decreased expression of BCL2 protein

PMID:21382956 PMID:27878984 PMID:29069573

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL2-related protein A1

increases expression

sulforaphane results in increased expression of BCL2A1 mRNA

NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998

G

Bcl2-like 1

multiple interactions
decreases expression

sulforaphane inhibits the reaction [sulforaphane results in decreased expression of BCL2L1 protein]

PMID:21684301 PMID:26833863

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

BCL3, transcription coactivator

decreases expression

sulforaphane results in decreased expression of BCL3 mRNA

NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:79,471,369...79,485,607

G

BCL6, transcription repressor

increases expression
decreases expression

sulforaphane results in increased expression of BCL6 mRNA
sulforaphane results in decreased expression of BCL6 mRNA

PMID:26833863 PMID:31838189

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389

G

3-hydroxybutyrate dehydrogenase 1

increases expression

sulforaphane results in increased expression of BDH1 mRNA

NCBI chr11:82,806,125...82,848,133
Ensembl chr11:69,302,534...69,337,671

G

bradykinin receptor B2

decreases expression

sulforaphane results in decreased expression of BDKRB2 mRNA

NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497

G

brain-derived neurotrophic factor

multiple interactions
increases expression
decreases expression

sulforaphane promotes the reaction [Pyruvaldehyde results in increased expression of BDNF protein]
sulforaphane results in increased expression of BDNF protein
sulforaphane results in decreased expression of BDNF mRNA

PMID:25933243 PMID:31838189

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615

G

beclin 1

multiple interactions

sulforaphane inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742

G

BEN domain containing 6

increases expression

sulforaphane results in increased expression of BEND6 mRNA

NCBI chr 9:43,576,982...43,631,437
Ensembl chr 9:36,081,484...36,135,228

G

brain expressed, X-linked 4

decreases expression

sulforaphane results in decreased expression of BEX4 mRNA

NCBI chr X:103,923,609...103,925,041
Ensembl chr X:99,131,942...99,133,531

G

basic helix-loop-helix family, member e40

increases expression

sulforaphane results in increased expression of BHLHE40 mRNA

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:141,618,476...141,624,774

G

BH3 interacting domain death agonist

multiple interactions
increases expression

sulforaphane inhibits the reaction [sulforaphane results in increased expression of BID protein]
[sulforaphane co-treated with TNFSF10 protein] results in increased cleavage of BID protein

PMID:21684301 PMID:26833863 PMID:29792947

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720

G

bridging integrator 2

increases expression

sulforaphane results in increased expression of BIN2 mRNA

NCBI chr 7:133,620,782...133,647,019
Ensembl chr 7:131,742,002...131,786,285

G

baculoviral IAP repeat-containing 3

increases expression

sulforaphane results in increased expression of BIRC3 mRNA

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802

G

Bcl2 modifying factor

decreases expression

sulforaphane results in decreased expression of BMF mRNA

NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145

G

bone morphogenetic protein 2

decreases expression

sulforaphane results in decreased expression of BMP2 mRNA

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397

G

bone morphogenetic protein 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BMP4 mRNA

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306

G

bora, aurora kinase A activator

increases expression

sulforaphane results in increased expression of BORA mRNA

NCBI chr15:82,205,467...82,243,499
Ensembl chr15:75,797,891...75,821,322

G

BMP/retinoic acid inducible neural specific 3

decreases expression

sulforaphane results in decreased expression of BRINP3 mRNA

NCBI chr13:60,964,127...61,397,044
Ensembl chr13:58,413,883...58,846,770

G

BRO1 domain and CAAX motif containing

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BROX mRNA

NCBI chr13:97,451,736...97,471,598
Ensembl chr13:94,920,112...94,940,227

G

BR serine/threonine kinase 2

decreases expression

sulforaphane results in decreased expression of BRSK2 mRNA

NCBI chr 1:206,465,040...206,518,156
Ensembl chr 1:197,035,633...197,088,092

G

bone marrow stromal cell antigen 1

increases expression

sulforaphane results in increased expression of BST1 mRNA

NCBI chr14:71,466,179...71,482,671
Ensembl chr14:67,252,998...67,270,180

G

B-TFIID TATA-box binding protein associated factor 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BTAF1 mRNA

NCBI chr 1:244,065,728...244,156,457
Ensembl chr 1:234,653,156...234,743,903

G

BTG anti-proliferation factor 2

increases expression

sulforaphane results in increased expression of BTG2 mRNA

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628

G

butyrophilin-like 9

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BTNL9 mRNA
sulforaphane results in increased expression of BTNL9 mRNA

NCBI chr10:33,967,098...33,990,304
Ensembl chr10:33,470,536...33,489,025

G

BUB1 mitotic checkpoint serine/threonine kinase

increases expression

sulforaphane results in increased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:115,020,254...115,051,650

G

similar to human chromosome 22 open reading frame 39

decreases expression

sulforaphane results in decreased expression of C22ORF39 mRNA

NCBI chr11:95,660,135...95,665,750
Ensembl chr11:82,159,528...82,160,235

G

similar to human chromosome 1 open reading frame 115

decreases expression

sulforaphane results in decreased expression of C1ORF115 mRNA

NCBI chr13:98,953,841...98,963,577
Ensembl chr13:96,422,302...96,432,068

G

similar to human chromosome 1 open reading frame 53

decreases expression

sulforaphane results in decreased expression of C1ORF53 mRNA

NCBI chr13:52,965,244...52,970,432
Ensembl chr13:50,413,785...50,419,120

G

similar to human chromosome 1 open reading frame 198

decreases expression

sulforaphane results in decreased expression of C1ORF198 mRNA

NCBI chr19:69,501,453...69,526,826
Ensembl chr19:52,604,060...52,629,436

G

similar to human chromosome 11 open reading frame 86

decreases expression

sulforaphane results in decreased expression of C11ORF86 mRNA

NCBI chr 1:211,213,429...211,225,624
Ensembl chr 1:201,784,009...201,785,916

G

complement C1q like 1

decreases expression

sulforaphane results in decreased expression of C1QL1 mRNA

NCBI chr10:88,402,219...88,409,649
Ensembl chr10:87,902,137...87,909,310

G

C1q and TNF related 1

decreases expression

sulforaphane results in decreased expression of C1QTNF1 mRNA

NCBI chr10:104,159,021...104,180,253
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 6

decreases expression

sulforaphane results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:111,958,348...111,964,948
Ensembl chr 7:110,077,878...110,084,412

G

complement C1r

decreases expression

sulforaphane results in decreased expression of C1R mRNA

NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:157,412,692...157,423,484

G

complement C3

increases expression
decreases expression

sulforaphane results in increased expression of C3 mRNA
sulforaphane results in decreased expression of C3 mRNA

PMID:26833863 PMID:31838189

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429

G

complement C3a receptor 1

increases expression

sulforaphane results in increased expression of C3AR1 mRNA

NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:156,075,389...156,084,701

G

complement component 4 binding protein, alpha

decreases expression

sulforaphane results in decreased expression of C4BPA mRNA

NCBI chr13:44,627,959...44,663,552
Ensembl chr13:42,075,717...42,111,205

G

complement C5

decreases expression

sulforaphane results in decreased expression of HC mRNA

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:18,270,696...18,361,994

G

similar to human chromosome 2 open reading frame 15

decreases expression

sulforaphane results in decreased expression of C2ORF15 mRNA

NCBI chr 9:47,596,762...47,601,833

G

similar to human chromosome 6 open reading frame 132

decreases expression

sulforaphane results in decreased expression of C6ORF132 mRNA

NCBI chr 9:13,524,822...13,561,756
Ensembl chr 9:13,525,395...13,561,585

G

calcium binding protein 39-like

increases expression

sulforaphane results in increased expression of CAB39L mRNA

NCBI chr15:37,782,778...37,885,191
Ensembl chr15:33,606,694...33,743,545

G

calcium binding tyrosine phosphorylation regulated

increases expression

sulforaphane results in increased expression of CABYR mRNA

NCBI chr18:4,166,790...4,178,570
Ensembl chr18:3,892,132...3,903,840

G

calcium voltage-gated channel auxiliary subunit beta 1

decreases expression

sulforaphane results in decreased expression of CACNB1 mRNA

NCBI chr10:83,494,509...83,515,164
Ensembl chr10:82,998,182...83,018,694

G

calcium dependent secretion activator 2

decreases expression

sulforaphane results in decreased expression of CADPS2 mRNA

NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:51,781,053...52,309,829

G

calcitonin receptor

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CALCR mRNA

NCBI chr 4:32,615,955...32,691,075
Ensembl chr 4:31,661,273...31,736,392

G

calmodulin-like 3

increases expression

sulforaphane results in increased expression of CALML3 mRNA

NCBI chr17:71,329,438...71,333,068
Ensembl chr17:66,419,882...66,423,175

G

calcium/calmodulin-dependent protein kinase ID

decreases expression

sulforaphane results in decreased expression of CAMK1D mRNA

NCBI chr17:77,491,191...77,892,018
Ensembl chr17:72,581,979...72,980,556

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

decreases expression

sulforaphane results in decreased expression of CAMK2N1 mRNA

NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600

G

capping actin protein, gelsolin like

increases expression

sulforaphane results in increased expression of CAPG mRNA

NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:104,594,753...104,611,856

G

calpain, small subunit 1

affects binding

CAPNS1 protein binds to sulforaphane

NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:85,444,608...85,454,795

G

carbonic anhydrase 3

increases expression

sulforaphane results in increased expression of CAR3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280

G

caspase recruitment domain family, member 19

increases expression

sulforaphane results in increased expression of CARD19 mRNA

NCBI chr17:15,432,632...15,445,317
Ensembl chr17:15,432,612...15,445,318

G

calcium regulated heat stable protein 1

decreases expression

sulforaphane results in decreased expression of CARHSP1 mRNA

NCBI chr10:7,453,602...7,467,218
Ensembl chr10:6,946,959...7,020,019

G

capping protein regulator and myosin 1 linker 1

decreases expression

sulforaphane results in decreased expression of CARMIL1 mRNA

NCBI chr17:41,235,819...41,516,204
Ensembl chr17:40,808,389...41,088,326

G

cysteinyl-tRNA synthetase 1

increases expression

sulforaphane results in increased expression of CARS1 mRNA

NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:198,753,691...198,795,941

G

calcium/calmodulin dependent serine protein kinase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CASK mRNA

NCBI chr X:11,572,328...11,915,831
Ensembl chr X:8,899,833...9,238,694

G

caspase 1

multiple interactions

sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CASP1 protein]

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

multiple interactions

sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]

NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions
increases activity

[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP3 protein]]; NGF protein inhibits the reaction [sulforaphane results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Pyruvaldehyde results in increased activity of CASP3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]
sulforaphane inhibits the reaction [cyanoginosin LR results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 protein]; sulforaphane inhibits the reaction [Ethanol results in increased expression of CASP3 protein modified form]; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP3 mRNA]

PMID:19780897 PMID:21684301 PMID:22922937 PMID:23518299 PMID:24967692 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

multiple interactions

[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092

G

caspase 7

increases activity

sulforaphane results in increased activity of CASP7 protein

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

multiple interactions
increases expression

[sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP8 protein; sulforaphane results in increased expression of and results in increased activity of CASP8 protein
sulforaphane results in increased expression of CASP8 mRNA

PMID:26833863 PMID:29792947 PMID:31838189

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
increases activity
increases expression
decreases expression

[sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP9 protein; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP9 protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in increased activity of CASP9 protein]; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP9 protein]
sulforaphane results in increased activity of CASP9 protein
sulforaphane results in increased expression of CASP9 protein
sulforaphane results in decreased expression of CASP9 mRNA
sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 mRNA]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 protein]

PMID:19780897 PMID:26833863 PMID:27878984 PMID:29792947 PMID:31838189 More...

Ensembl chr 5:154,109,046...154,126,626

G

calsequestrin 2

increases expression

sulforaphane results in increased expression of CASQ2 mRNA

NCBI chr 2:192,214,556...192,270,821
Ensembl chr 2:189,525,960...189,582,267

G

castor zinc finger 1

decreases expression

sulforaphane results in decreased expression of CASZ1 mRNA

NCBI chr 5:164,527,083...164,677,037
Ensembl chr 5:159,243,995...159,393,400

G

catalase

multiple interactions
increases activity
increases expression

sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Cisplatin results in decreased expression of CAT protein]
sulforaphane results in increased activity of CAT protein
sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
sulforaphane results in increased expression of CAT mRNA; sulforaphane results in increased expression of CAT protein
brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in decreased activity of CAT protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased activity of CAT protein]

PMID:19913604 PMID:22664424 PMID:24967692 PMID:29353218 PMID:29964319 More...

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

Cbl proto-oncogene B

increases expression

sulforaphane results in increased expression of CBLB mRNA

NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839

G

carbonyl reductase 3

multiple interactions
increases expression

[sulforaphane co-treated with dibenzoylmethane] results in increased expression of CBR3 mRNA
sulforaphane results in increased expression of CBR3 mRNA

PMID:17942926 PMID:20806931 PMID:31838189

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:33,008,615...33,016,875

G

chromobox 6

increases expression

sulforaphane results in increased expression of CBX6 mRNA

NCBI chr 7:113,253,364...113,263,413
Ensembl chr 7:111,372,980...111,383,091

G

coiled-coil domain containing 102A

decreases expression

sulforaphane results in decreased expression of CCDC102A mRNA

NCBI chr19:10,108,553...10,124,652
Ensembl chr19:10,103,361...10,118,657

G

coiled-coil domain containing 13

increases expression

sulforaphane results in increased expression of CCDC13 mRNA

NCBI chr 8:130,335,797...130,391,658
Ensembl chr 8:121,457,697...121,502,337

G

coiled-coil domain containing 18

increases expression

sulforaphane results in increased expression of CCDC18 mRNA

NCBI chr14:1,646,725...1,752,581
Ensembl chr14:1,501,784...1,607,711

G

coiled-coil domain containing 24

increases expression

sulforaphane results in increased expression of CCDC24 mRNA

NCBI chr 5:136,684,206...136,697,855
Ensembl chr 5:131,408,143...131,412,029

G

coiled coil domain containing 28B

decreases expression

sulforaphane results in decreased expression of CCDC28B mRNA

NCBI chr 5:147,246,627...147,251,629
Ensembl chr 5:141,962,276...141,967,382

G

coiled-coil domain containing 3

decreases expression

sulforaphane results in decreased expression of CCDC3 mRNA

NCBI chr17:77,941,148...78,044,820
Ensembl chr17:73,035,045...73,135,337

G

coiled-coil domain containing 80

increases expression
decreases expression

sulforaphane results in increased expression of CCDC80 mRNA
sulforaphane results in decreased expression of CCDC80 mRNA

PMID:30529165 PMID:31838189

NCBI chr11:69,191,188...69,224,844
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 11

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL11 mRNA

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 2

multiple interactions
increases expression
decreases expression

sulforaphane inhibits the reaction [Cyclosporine results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
sulforaphane results in increased expression of CCL2 mRNA
sulforaphane metabolite results in decreased expression of CCL2 mRNA; sulforaphane results in decreased expression of CCL2 mRNA
sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CCL2 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CCL2 mRNA]

PMID:23958496 PMID:26833863 PMID:32387680 PMID:35724838

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

increases expression
multiple interactions

sulforaphane results in increased expression of CCL20 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL20 mRNA

PMID:26833863 PMID:30529165

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 5

multiple interactions

sulforaphane inhibits the reaction [Cyclosporine results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 2

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of CCN2 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]

PMID:24707343 PMID:24967692 PMID:29353218 PMID:30096613

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 5

decreases expression

sulforaphane results in decreased expression of CCN5 mRNA

NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:152,491,220...152,502,636

G

cyclin B1

increases expression

sulforaphane results in increased expression of CCNB1 mRNA; sulforaphane results in increased expression of CCNB1 protein

PMID:15231455 PMID:31838189

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

increases expression

sulforaphane results in increased expression of CCNB2 mRNA

NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

increases expression

sulforaphane results in increased expression of CCND1 protein
sulforaphane results in increased expression of CCND1 mRNA

PMID:17942926 PMID:31838189

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

increases expression
multiple interactions

sulforaphane results in increased expression of CCND3 mRNA
sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein]

PMID:26833863 PMID:33007382

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

increases expression

sulforaphane results in increased expression of CCNE1 mRNA

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

decreases expression

sulforaphane results in decreased expression of CCNE2 mRNA

NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632

G

cyclin J

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCNJ mRNA
sulforaphane results in decreased expression of CCNJ mRNA

NCBI chr 1:249,608,991...249,626,798

G

cyclin J-like

increases expression

sulforaphane results in increased expression of CCNJL mRNA

NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426

G

cyclin Y-like 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCNYL1 mRNA

NCBI chr 9:73,565,484...73,601,926
Ensembl chr 9:66,071,543...66,107,999

G

cell cycle progression 1

increases expression

sulforaphane results in increased expression of CCPG1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:73,719,955...73,752,430

G

C-C motif chemokine receptor 2

decreases expression

sulforaphane results in decreased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 4

affects methylation

sulforaphane affects the methylation of CCR4 promoter

NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:114,176,974...114,178,056

G

chaperonin containing TCP1 subunit 2

affects binding
multiple interactions

CCT2 protein binds to sulforaphane
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCT2 mRNA

PMID:21838287 PMID:30529165

NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:52,692,725...52,706,944

G

chaperonin containing TCP1 subunit 8

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCT8 mRNA

NCBI chr11:40,196,619...40,208,328
Ensembl chr11:26,710,370...26,722,079

G

CD14 molecule

increases expression

sulforaphane results in increased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261

G

CD163 molecule

increases expression

sulforaphane results in increased expression of CD163 mRNA

NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878

G

CD180 molecule

decreases expression

sulforaphane results in decreased expression of CD180 mRNA

NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:33,855,991...33,899,936

G

CD22 molecule

increases expression

sulforaphane results in increased expression of CD22 mRNA

NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:86,117,459...86,132,322

G

CD24 molecule

decreases expression

sulforaphane results in decreased expression of CD24 mRNA

NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662

G

Cd300 molecule-like family member F

increases expression

sulforaphane results in increased expression of CD300LF mRNA

NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,359,943...100,376,041

G

Cd68 molecule

increases expression

sulforaphane results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697

G

Cd70 molecule

decreases expression

sulforaphane results in decreased expression of CD70 mRNA

NCBI chr 9:2,093,540...2,096,692
Ensembl chr 9:2,006,563...2,009,715

G

CD74 molecule

decreases expression

sulforaphane results in decreased expression of CD74 mRNA

NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003

G

Cd82 molecule

decreases expression

sulforaphane results in decreased expression of CD82 mRNA

NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:79,385,887...79,431,809

G

CD83 molecule

decreases expression

sulforaphane results in decreased expression of CD83 mRNA

NCBI chr17:21,093,281...21,113,223
Ensembl chr17:20,887,309...20,907,083

G

CD84 molecule

decreases expression
increases expression

sulforaphane results in decreased expression of CD84 mRNA
sulforaphane results in increased expression of CD84 mRNA

PMID:26833863 PMID:31838189

NCBI chr13:86,859,979...86,899,984
Ensembl chr13:84,327,553...84,362,076

G

cytidine deaminase

increases expression
decreases expression

sulforaphane results in increased expression of CDA mRNA
sulforaphane results in decreased expression of CDA mRNA

PMID:26833863 PMID:31838189

NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:150,556,615...150,583,231

G

cell division cycle 16

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CDC16 mRNA

NCBI chr16:82,475,234...82,498,797
Ensembl chr16:75,773,028...75,796,550

G

cell division cycle 20

increases expression

sulforaphane results in increased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512

G

CDC42 binding protein kinase gamma

decreases expression

sulforaphane results in decreased expression of CDC42BPG mRNA

NCBI chr 1:213,037,603...213,057,764
Ensembl chr 1:203,608,574...203,628,502

G

cadherin 1

multiple interactions
increases expression
decreases expression
increases methylation

sulforaphane inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]
sulforaphane results in increased expression of CDH1
sulforaphane results in decreased expression of CDH1 mRNA
sulforaphane results in increased methylation of CDH1 gene

PMID:28624451 PMID:29899271 PMID:31838189

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775

G

cadherin 10

decreases expression

sulforaphane results in decreased expression of CDH10 mRNA

NCBI chr 2:70,355,521...70,577,880
Ensembl chr 2:68,628,780...68,850,995

G

cadherin 2

increases expression

sulforaphane results in increased expression of CDH2 mRNA

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:7,776,704...7,990,167

G

cadherin 5

decreases expression

sulforaphane results in decreased expression of CDH5 mRNA

NCBI chr19:821,875...860,931
Ensembl chr19:815,411...854,368

G

cadherin-related family member 4

increases expression

sulforaphane results in increased expression of CDHR4 mRNA

NCBI chr 8:117,561,206...117,594,456
Ensembl chr 8:108,682,613...108,690,367

G

cyclin-dependent kinase 1

increases expression

sulforaphane results in increased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 18

decreases expression

sulforaphane results in decreased expression of CDK18 mRNA

NCBI chr13:46,107,763...46,140,705
Ensembl chr13:43,556,748...43,588,525

G

cyclin-dependent kinase 6

multiple interactions

sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CDK6 protein]

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase-like 4

increases expression

sulforaphane results in increased expression of CDKL4 mRNA

NCBI chr 6:20,202,047...20,244,821
Ensembl chr 6:14,450,681...14,492,046

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

sulforaphane results in increased expression of CDKN1A mRNA; sulforaphane results in increased expression of CDKN1A protein
sulforaphane inhibits the reaction [triptolide affects the expression of CDKN1A protein]

PMID:15231455 PMID:17937621 PMID:31838189 PMID:36990132

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

decreases expression

sulforaphane results in decreased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

multiple interactions
decreases expression

sulforaphane inhibits the reaction [[NFE2L2 protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of CDKN2A mRNA]; sulforaphane promotes the reaction [1,2-Dimethylhydrazine results in increased expression of CDKN2A mRNA]; sulforaphane promotes the reaction [1,2-Dimethylhydrazine results in increased expression of CDKN2A protein]
sulforaphane results in decreased expression of CDKN2A mRNA

PMID:26388957 PMID:30529165

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149

G

CDKN2A interacting protein

decreases expression

sulforaphane results in decreased expression of CDKN2AIP mRNA

NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033

G

CDKN2A interacting protein N-terminal like

decreases expression

sulforaphane results in decreased expression of CDKN2AIPNL mRNA

NCBI chr10:36,731,983...36,741,500
Ensembl chr10:36,231,087...36,240,564

G

CCAAT/enhancer binding protein delta

decreases expression

sulforaphane results in decreased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:84,764,565...84,765,829

G

CCAAT/enhancer binding protein epsilon

increases expression

sulforaphane results in increased expression of CEBPE mRNA

NCBI chr15:32,139,716...32,141,476
Ensembl chr15:28,169,704...28,171,814

G

centrosomal AT-AC splicing factor

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CENATAC mRNA
sulforaphane results in decreased expression of CENATAC mRNA

NCBI chr 8:53,632,777...53,639,661
Ensembl chr 8:44,735,972...44,742,837

G

centromere protein I

increases expression

sulforaphane results in increased expression of CENPI mRNA

NCBI chr X:101,809,192...101,860,935
Ensembl chr X:97,515,972...97,567,657

G

centrosomal protein 20

increases expression

sulforaphane results in increased expression of CEP20 mRNA

NCBI chr10:1,221,294...1,243,144
Ensembl chr10:714,151...736,837

G

centrosomal protein 55

increases expression

sulforaphane results in increased expression of CEP55 mRNA

NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:235,832,878...235,848,394

G

centrosomal protein 70

decreases expression

sulforaphane results in decreased expression of CEP70 mRNA

NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855

G

carboxylesterase 1D

multiple interactions
increases expression

NFE2L2 protein affects the reaction [sulforaphane results in increased expression of CES1 mRNA alternative form]; sulforaphane promotes the reaction [[NFE2L2 protein binds to CES1 promoter] which results in increased expression of CES1 mRNA alternative form]; sulforaphane promotes the reaction [NFE2L2 protein binds to CES1 promoter]; sulforaphane results in increased expression of and results in increased activity of CES1 protein alternative form
sulforaphane results in increased expression of CES1 mRNA; sulforaphane results in increased expression of CES1 mRNA alternative form

PMID:19715681 PMID:26833863

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 3a

decreases expression

sulforaphane results in decreased expression of CES3 mRNA

NCBI chr19:49,902,312...49,910,484

G

cilia and flagella associated protein 144

increases expression

sulforaphane results in increased expression of CFAP144 mRNA

NCBI chr10:44,009,412...44,019,281
Ensembl chr10:43,509,826...43,520,086

G

cilia and flagella associated protein 251

increases expression

sulforaphane results in increased expression of CFAP251 mRNA

NCBI chr12:38,923,154...38,997,881
Ensembl chr12:33,261,476...33,293,932

G

complement factor D

increases expression

sulforaphane results in increased expression of CFD mRNA

NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:9,813,150...9,815,053

G

complement factor properdin

increases expression

sulforaphane results in increased expression of CFP mRNA

NCBI chr X:3,715,551...3,721,113
Ensembl chr X:1,161,979...1,167,573

G

CF transmembrane conductance regulator

decreases expression

sulforaphane results in decreased expression of CFTR mRNA

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

sulforaphane results in decreased expression of CHAC1 mRNA

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526

G

chitinase, acidic

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CHIA mRNA

NCBI chr 2:196,302,687...196,344,849
Ensembl chr 2:193,614,114...193,656,533

G

chimerin 1

increases expression

sulforaphane results in increased expression of CHN1 mRNA

NCBI chr 3:78,917,329...79,084,040
Ensembl chr 3:58,510,536...58,676,490

G

cysteine and histidine rich domain containing 1

increases expression

sulforaphane results in increased expression of CHORDC1 mRNA

NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:15,374,471...15,399,162

G

cholinergic receptor nicotinic beta 1 subunit

decreases expression

sulforaphane results in decreased expression of CHRNB1 mRNA

NCBI chr10:54,999,943...55,015,137
Ensembl chr10:54,501,093...54,516,345

G

carbohydrate sulfotransferase 13

decreases expression

sulforaphane results in decreased expression of CHST13 mRNA

NCBI chr 4:124,381,226...124,395,143
Ensembl chr 4:122,824,022...122,838,019

G

carbohydrate sulfotransferase 15

increases expression

sulforaphane results in increased expression of CHST15 mRNA

NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:187,028,970...187,107,707

G

carbohydrate sulfotransferase 2

decreases expression

sulforaphane results in decreased expression of CHST2 mRNA

NCBI chr 8:104,839,716...104,845,961
Ensembl chr 8:95,959,826...95,966,955

G

cell death-inducing DFFA-like effector a

increases expression

sulforaphane results in increased expression of CIDEA mRNA

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:60,894,874...60,920,481

G

cartilage intermediate layer protein 2

increases expression

sulforaphane results in increased expression of CILP2 mRNA

PMID:30529165 PMID:31838189

NCBI chr16:19,573,821...19,581,100
Ensembl chr16:19,539,706...19,547,191

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

sulforaphane results in decreased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:12,312,160...12,314,897

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

decreases expression

sulforaphane results in decreased expression of CITED4 mRNA

NCBI chr 5:139,532,165...139,533,056
Ensembl chr 5:134,246,682...134,248,135

G

creatine kinase B

decreases expression

sulforaphane results in decreased expression of CKB mRNA

NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:130,729,423...130,732,315

G

CDC28 protein kinase regulatory subunit 2

increases expression

sulforaphane results in increased expression of CKS2 mRNA

NCBI chr17:13,722,360...13,727,519

G

chloride voltage-gated channel 4

increases expression

sulforaphane results in increased expression of CLCN4 mRNA

NCBI chr X:27,290,769...27,356,967
Ensembl chr X:23,729,338...23,793,238

G

claudin 4

increases expression

sulforaphane results in increased expression of CLDN4 mRNA

NCBI chr12:27,388,160...27,389,958
Ensembl chr12:21,751,331...21,753,436

G

claudin 7

decreases expression

sulforaphane results in decreased expression of CLDN7 mRNA

NCBI chr10:55,188,670...55,190,871
Ensembl chr10:54,689,987...54,692,171

G

C-type lectin domain containing 10A

increases expression

sulforaphane results in increased expression of CLEC10A mRNA

NCBI chr10:55,374,914...55,379,110
Ensembl chr10:54,876,260...54,880,435

G

C-type lectin domain family 4, member D

increases expression

sulforaphane results in increased expression of CLEC4D mRNA

NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:156,589,792...156,598,848

G

C-type lectin domain family 4, member E

increases expression

sulforaphane results in increased expression of CLEC4E mRNA

NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:156,607,614...156,612,767

G

calmegin

increases expression

sulforaphane results in increased expression of CLGN mRNA

NCBI chr19:41,601,568...41,633,207
Ensembl chr19:24,696,875...24,728,758

G

chloride intracellular channel 3

decreases expression

sulforaphane results in decreased expression of CLIC3 mRNA

NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:8,272,097...8,274,018

G

chloride intracellular channel 6

increases expression

sulforaphane results in increased expression of CLIC6 mRNA

NCBI chr11:45,223,715...45,266,261
Ensembl chr11:31,737,813...31,780,061

G

CLPTM1 regulator of GABA type A receptor forward trafficking

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CLPTM1 mRNA

NCBI chr 1:88,417,447...88,449,047
Ensembl chr 1:79,289,477...79,321,092

G

calsyntenin 2

decreases expression

sulforaphane results in decreased expression of CLSTN2 mRNA

NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:98,021,666...98,637,731

G

clusterin

multiple interactions

[sulforaphane co-treated with dibenzoylmethane] results in decreased expression of CLU mRNA

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315

G

clustered mitochondria homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CLUH mRNA

NCBI chr10:60,008,052...60,029,742
Ensembl chr10:59,509,726...59,531,345

G

citramalyl-CoA lyase

increases expression

sulforaphane results in increased expression of CLYBL mRNA

NCBI chr15:105,690,283...105,912,347
Ensembl chr15:99,283,650...99,505,695

G

cornifelin

decreases expression

sulforaphane results in decreased expression of CNFN mRNA

NCBI chr 1:90,079,409...90,081,556
Ensembl chr 1:80,951,600...80,953,747

G

cyclic nucleotide gated channel subunit beta 1

decreases expression

sulforaphane results in decreased expression of CNGB1 mRNA

NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,726,595...9,791,173

G

cornichon family AMPA receptor auxiliary protein 2

increases expression

sulforaphane results in increased expression of CNIH2 mRNA

NCBI chr 1:211,828,791...211,834,474
Ensembl chr 1:202,399,419...202,405,089

G

calponin 1

increases expression

sulforaphane results in increased expression of CNN1 mRNA

NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:20,632,338...20,641,098

G

calponin 3

decreases expression

sulforaphane results in decreased expression of CNN3 mRNA

NCBI chr 2:212,203,661...212,234,772
Ensembl chr 2:209,518,948...209,550,104

G

CCR4-NOT transcription complex, subunit 6

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CNOT6 mRNA

NCBI chr10:34,479,892...34,532,166
Ensembl chr10:33,980,831...34,031,025

G

CCR4-NOT transcription complex subunit 9

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CNOT9 mRNA

NCBI chr 9:83,533,369...83,558,207
Ensembl chr 9:76,084,334...76,109,100

G

cannabinoid receptor 2

multiple interactions

[LEPR protein affects the susceptibility to sulforaphane] which affects the expression of CNR2 protein

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:148,125,604...148,151,548

G

contactin associated protein 1

decreases expression

sulforaphane results in decreased expression of CNTNAP1 mRNA

NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,111,643...86,125,611

G

contactin associated protein family member 3

decreases expression

sulforaphane results in decreased expression of CNTNAP3 mRNA

NCBI chr17:273,137...461,233
Ensembl chr17:267,508...454,102

G

cytochrome c oxidase assembly factor 6

increases expression

sulforaphane results in increased expression of COA6 mRNA

NCBI chr19:71,293,066...71,295,668
Ensembl chr19:54,395,742...54,399,407

G

cordon-bleu WH2 repeat protein-like 1

decreases expression

sulforaphane results in decreased expression of COBLL1 mRNA

NCBI chr 3:70,161,369...70,324,844
Ensembl chr 3:49,753,262...49,915,194

G

collagen type I alpha 1 chain

decreases expression

sulforaphane results in decreased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 5 chain

increases methylation
decreases expression

sulforaphane results in increased methylation of COL4A5 gene
sulforaphane results in decreased expression of COL4A5 mRNA

NCBI chr X:109,907,251...110,111,214
Ensembl chr X:105,118,820...105,322,692

G

collagen type IV alpha 6 chain

decreases expression

sulforaphane results in decreased expression of COL4A6 mRNA

NCBI chr X:109,554,945...109,905,987
Ensembl chr X:104,766,957...105,117,500

G

collagen type V alpha 1 chain

decreases expression
increases methylation

sulforaphane results in decreased expression of COL5A1 mRNA
sulforaphane results in increased methylation of COL5A1 gene

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:11,208,512...11,354,588

G

collagen type IX alpha 3 chain

decreases expression

sulforaphane results in decreased expression of COL9A3 mRNA

NCBI chr 3:188,089,337...188,112,034
Ensembl chr 3:167,711,840...167,734,465

G

catechol-O-methyltransferase

multiple interactions

sulforaphane inhibits the reaction [DNMT3B protein binds to COMT promoter]; sulforaphane inhibits the reaction [EP300 protein binds to COMT promoter]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [DNMT3B protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in decreased expression of COMT mRNA]; sulforaphane inhibits the reaction [Estradiol results in increased methylation of COMT promoter]; sulforaphane inhibits the reaction [Genistein promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Genistein promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Genistein results in decreased expression of COMT mRNA]; sulforaphane inhibits the reaction [Genistein results in increased methylation of COMT promoter]; sulforaphane inhibits the reaction [HDAC1 protein binds to COMT promoter]

NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642

G

coenzyme Q9

increases expression

sulforaphane results in increased expression of COQ9 mRNA

NCBI chr19:10,172,943...10,185,960
Ensembl chr19:10,166,951...10,179,949

G

corin, serine peptidase

increases expression

sulforaphane results in increased expression of CORIN mRNA

NCBI chr14:36,034,613...36,264,671
Ensembl chr14:35,681,304...35,909,503

G

coronin 6

decreases expression

sulforaphane results in decreased expression of CORO6 mRNA

NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,311,660...62,319,659

G

cytochrome c oxidase subunit 5A

increases expression

sulforaphane results in increased expression of COX5A mRNA

NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:57,922,290...57,933,781

G

cytochrome c oxidase subunit 5B

increases expression

sulforaphane results in increased expression of COX5B mRNA

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:38,921,967...38,925,052

G

cytochrome c oxidase subunit 6A2

increases expression

sulforaphane results in increased expression of COX6A2 mRNA

NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:182,788,528...182,789,274

G

cytochrome c oxidase subunit 7A1

increases expression

sulforaphane results in increased expression of COX7A1 mRNA

NCBI chr 1:94,549,663...94,572,330
Ensembl chr 1:85,441,871...85,445,151

G

carboxypeptidase A4

decreases expression

sulforaphane results in decreased expression of CPA4 mRNA

NCBI chr 4:60,155,675...60,179,644
Ensembl chr 4:59,188,284...59,212,255

G

centrosome assembly and centriole elongation protein

increases expression
decreases methylation

sulforaphane results in increased expression of CPAP mRNA
sulforaphane results in decreased methylation of CPAP gene

NCBI chr15:34,742,838...34,806,020
Ensembl chr15:30,627,224...30,686,791

G

carboxypeptidase D

increases expression

sulforaphane results in increased expression of CPD mRNA

NCBI chr10:62,121,681...62,185,638
Ensembl chr10:61,623,526...61,687,491

G

cytoplasmic polyadenylation element binding protein 2

decreases methylation

sulforaphane results in decreased methylation of CPEB2 gene

NCBI chr14:71,999,958...72,056,012
Ensembl chr14:67,787,507...67,840,743

G

cytoplasmic polyadenylation element binding protein 4

decreases expression

sulforaphane results in decreased expression of CPEB4 mRNA

NCBI chr10:16,222,271...16,284,248
Ensembl chr10:15,717,794...15,780,603

G

cadherin-like and PC-esterase domain containing 1

decreases expression

sulforaphane results in decreased expression of CPED1 mRNA

NCBI chr 4:51,482,497...51,755,440
Ensembl chr 4:50,516,819...50,788,674

G

ciliogenesis and planar polarity effector complex subunit 1

decreases expression

sulforaphane results in decreased expression of CPLANE1 mRNA

NCBI chr 2:58,996,119...59,096,817
Ensembl chr 2:57,268,884...57,369,500

G

carboxypeptidase M

decreases expression

sulforaphane results in decreased expression of CPM mRNA

PMID:30529165 PMID:31838189

NCBI chr 7:55,111,599...55,172,114
Ensembl chr 7:53,225,696...53,286,220

G

carbamoyl-phosphate synthase 1

decreases expression

sulforaphane results in decreased expression of CPS1 mRNA

NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

increases expression

sulforaphane results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

increases expression

sulforaphane results in increased expression of CPZ mRNA

NCBI chr14:79,448,242...79,471,557
Ensembl chr14:75,223,605...75,246,945

G

complement C3b/C4b receptor 1 like

increases expression

sulforaphane results in increased expression of CR1L mRNA

NCBI chr13:109,138,132...109,189,068
Ensembl chr13:106,574,858...106,660,445

G

cellular retinoic acid binding protein 2

decreases expression

sulforaphane results in decreased expression of CRABP2 mRNA

NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:173,416,857...173,421,379

G

CRACD like

increases expression

sulforaphane results in increased expression of CRACDL mRNA

NCBI chr 9:47,323,785...47,446,612
Ensembl chr 9:39,834,833...39,951,086

G

carnitine O-acetyltransferase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CRAT mRNA

NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:13,675,684...13,689,255

G

crumbs cell polarity complex component 3

decreases expression

sulforaphane results in decreased expression of CRB3 mRNA

NCBI chr 9:1,985,504...1,990,855
Ensembl chr 9:1,896,623...1,903,859

G

cAMP responsive element binding protein 5

decreases expression

sulforaphane results in decreased expression of CREB5 mRNA

NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:82,393,730...82,790,325

G

cellular repressor of E1A-stimulated genes 1

increases expression

sulforaphane results in increased expression of CREG1 mRNA

NCBI chr13:80,552,779...80,565,272
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich protein 2

decreases expression

sulforaphane results in decreased expression of CRIP2 mRNA

NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:132,221,082...132,226,065

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

sulforaphane results in decreased expression of CRISPLD2 mRNA

NCBI chr19:64,961,764...65,020,099
Ensembl chr19:48,053,287...48,110,465

G

CREB regulated transcription coactivator 3

decreases expression

sulforaphane results in decreased expression of CRTC3 mRNA

NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:134,554,696...134,655,500

G

crystallin, alpha B

decreases expression

sulforaphane results in decreased expression of CRYAB mRNA

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:51,093,441...51,099,157

G

citrate synthase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CS mRNA

NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:758,345...791,421

G

cold shock domain containing C2

decreases expression

sulforaphane results in decreased expression of CSDC2 mRNA

NCBI chr 7:115,332,134...115,346,599
Ensembl chr 7:113,451,998...113,466,463

G

colony stimulating factor 2

multiple interactions

sulforaphane inhibits the reaction [Vehicle Emissions analog results in increased expression of CSF2 protein]

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199

G

chondroitin sulfate proteoglycan 4

decreases expression

sulforaphane results in decreased expression of CSPG4 mRNA

NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:57,264,962...57,300,010

G

cysteine and glycine-rich protein 1

decreases expression

sulforaphane results in decreased expression of CSRP1 mRNA

NCBI chr13:49,709,928...49,731,141
Ensembl chr13:47,167,789...47,179,384

G

cysteine and glycine rich protein 3

increases expression

sulforaphane results in increased expression of CSRP3 mRNA

NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653

G

cystatin C

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CST3 mRNA

NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:136,336,920...136,340,822

G

CTD nuclear envelope phosphatase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDNEP1 mRNA

NCBI chr10:55,203,047...55,212,469
Ensembl chr10:54,704,148...54,713,781

G

CTD small phosphatase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDSP1 mRNA

NCBI chr 9:83,422,755...83,428,411
Ensembl chr 9:75,973,962...75,979,297

G

CTD small phosphatase like

decreases expression

sulforaphane results in decreased expression of CTDSPL mRNA

NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:118,642,672...118,767,117

G

CTD small phosphatase like 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDSPL2 mRNA

NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:108,915,280...108,967,227

G

cystathionine gamma-lyase

increases response to substance
decreases expression

CTH protein results in increased susceptibility to sulforaphane
sulforaphane results in decreased expression of CTH mRNA

PMID:22005276 PMID:30529165

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234

G

catenin delta 1

increases expression

sulforaphane results in increased expression of CTNND1 mRNA

NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:69,683,313...69,734,516

G

cathepsin G

decreases expression

sulforaphane results in decreased expression of CTSG mRNA

NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353

G

cathepsin L

increases expression

sulforaphane results in increased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548

G

cathepsin O

increases expression

sulforaphane results in increased expression of CTSO mRNA

NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:167,230,330...167,253,702

G

CTTNBP2 N-terminal like

decreases expression

sulforaphane results in decreased expression of CTTNBP2NL mRNA

NCBI chr 2:195,196,318...195,244,792
Ensembl chr 2:192,507,963...192,541,101

G

cortexin 1

decreases expression

sulforaphane results in decreased expression of CTXN1 mRNA

NCBI chr12:7,408,308...7,409,919

G

cullin 3

multiple interactions

sulforaphane inhibits the reaction [KEAP1 protein binds to CUL3 protein]

PMID:18417180 PMID:30261176

NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462

G

C-X-C motif chemokine ligand 1

multiple interactions
decreases expression
increases expression

sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]
sulforaphane metabolite results in decreased expression of CXCL1 mRNA; sulforaphane results in decreased expression of CXCL1 mRNA
sulforaphane results in increased expression of CXCL1 mRNA

PMID:32387680 PMID:35724838

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 17

increases expression

sulforaphane results in increased expression of CXCL17 mRNA

NCBI chr 1:90,112,561...90,124,648
Ensembl chr 1:80,984,964...80,996,726

G

C-X-C motif chemokine ligand 2

increases expression

sulforaphane results in increased expression of CXCL2 mRNA

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

decreases expression
multiple interactions
increases expression

sulforaphane metabolite results in decreased expression of CXCL1 mRNA; sulforaphane results in decreased expression of CXCL1 mRNA
sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]
sulforaphane results in increased expression of CXCL1 mRNA

PMID:32387680 PMID:35724838

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 5

increases expression

sulforaphane results in increased expression of CXCR5 mRNA

NCBI chr 8:53,738,878...53,756,813
Ensembl chr 8:44,843,413...44,857,893

G

cytochrome b-245 beta chain

increases expression

sulforaphane results in increased expression of CYBB mRNA

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586

G

cytochrome c-1

increases expression

sulforaphane results in increased expression of CYC1 mRNA

NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:108,067,115...108,069,479

G

cytochrome c, somatic

increases expression

sulforaphane results in increased expression of CYCS mRNA

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 2

increases expression

sulforaphane results in increased expression of CYFIP2 mRNA

NCBI chr10:31,122,653...31,242,440
Ensembl chr10:30,621,318...30,741,113

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions
affects expression
affects binding

sulforaphane results in increased expression of CYP1A1 protein
sulforaphane analog inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; sulforaphane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; sulforaphane results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]
sulforaphane inhibits the reaction [anthracene results in increased activity of CYP1A1 protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]
sulforaphane analog affects the expression of CYP1A1 mRNA
sulforaphane binds to CYP1A1 protein

PMID:18823965 PMID:19202560 PMID:19362136 PMID:22643862 PMID:22664424 More...

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
decreases expression
multiple interactions

sulforaphane results in increased expression of CYP1A2 protein
sulforaphane results in decreased expression of CYP1A2 mRNA
sulforaphane inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]; sulforaphane inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]
sulforaphane results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]

PMID:15906351 PMID:19202560 PMID:19362136 PMID:20442190 PMID:22664424

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

sulforaphane results in increased expression of CYP1B1 protein
sulforaphane results in increased expression of CYP1B1 mRNA

PMID:18823965 PMID:26833863

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CYP26B1 mRNA

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]
sulforaphane results in increased expression of CYP2E1 mRNA

PMID:21684301 PMID:30529165

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 39, subfamily a, polypeptide 1

increases expression

sulforaphane results in increased expression of CYP39A1 mRNA

NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:17,230,455...17,306,775

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases expression
decreases activity
decreases expression

sulforaphane results in decreased expression of and results in decreased activity of CYP3A2 protein
sulforaphane results in increased expression of CYP3A2 protein
sulforaphane results in decreased activity of CYP3A2 protein
sulforaphane inhibits the reaction [ginkgolide B results in increased expression of CYP3A4 mRNA]; sulforaphane inhibits the reaction [Rifampin results in increased expression of CYP3A4]
sulforaphane results in decreased expression of CYP3A4 mRNA

PMID:15906351 PMID:18823965 PMID:20442190 PMID:22664424 PMID:23153560 More...

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily f, polypeptide 18

increases expression

sulforaphane results in increased expression of CYP4F3 mRNA

PMID:26833863 PMID:31838189

NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

sulforaphane results in decreased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

sulforaphane results in decreased expression of CYP8B1 mRNA

NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166

G

DAB adaptor protein 2

decreases expression

sulforaphane results in decreased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

decreases expression

sulforaphane results in decreased expression of DAPP1 mRNA

NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:226,425,898...226,475,423

G

DDB1 and CUL4 associated factor 7

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DCAF7 mRNA

NCBI chr10:91,473,900...91,496,080
Ensembl chr10:90,974,095...90,996,275

G

decorin

increases expression
decreases expression

sulforaphane results in increased expression of DCN mRNA
sulforaphane results in decreased expression of DCN mRNA

PMID:30529165 PMID:31838189

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:32,281,252...32,321,270

G

dendrocyte expressed seven transmembrane protein

increases expression

sulforaphane results in increased expression of DCSTAMP mRNA

NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078

G

dimethylarginine dimethylaminohydrolase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DDAH1 mRNA

NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339

G

DDAH family member 2, ADMA-independent

decreases expression

sulforaphane results in decreased expression of DDAH2 mRNA

NCBI chr20:3,766,115...3,769,161
Ensembl chr20:3,761,465...3,764,511

G

damage specific DNA binding protein 2

decreases expression

sulforaphane results in decreased expression of DDB2 mRNA

NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:77,185,109...77,207,631

G

DNA damage-induced apoptosis suppressor

increases expression

sulforaphane results in increased expression of DDIAS mRNA

NCBI chr 1:156,318,559...156,342,869
Ensembl chr 1:146,906,154...146,930,462

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

sulforaphane inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
sulforaphane inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]
sulforaphane results in increased expression of DDIT3 protein

PMID:22922937 PMID:24967692 PMID:35724838 PMID:36670177

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

dendrin

decreases expression

sulforaphane results in decreased expression of DDN mRNA

NCBI chr 7:131,832,270...131,836,252
Ensembl chr 7:129,953,318...129,957,341

G

2,4-dienoyl-CoA reductase 1

increases expression

sulforaphane results in increased expression of DECR1 mRNA

NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:29,411,172...29,439,018

G

death effector domain-containing

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DEDD mRNA

NCBI chr13:86,286,341...86,301,789
Ensembl chr13:83,756,108...83,769,332

G

death effector domain containing 2

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DEDD2 mRNA

NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:80,792,000...80,807,714

G

DENN domain containing 2B

decreases expression

sulforaphane results in decreased expression of DENND2B mRNA

NCBI chr 1:172,978,895...173,129,623
Ensembl chr 1:163,544,074...163,694,680

G

DENN domain containing 3

decreases expression

sulforaphane results in decreased expression of DENND3 mRNA

NCBI chr 7:107,304,860...107,362,573
Ensembl chr 7:105,415,677...105,473,592

G

DEP domain containing 1

increases expression

sulforaphane results in increased expression of DEPDC1 mRNA

NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:248,684,523...248,717,951

G

DEP domain containing MTOR-interacting protein

decreases expression

sulforaphane results in decreased expression of DEPTOR mRNA

NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:86,514,988...86,667,773

G

desmin

affects binding
increases expression

DES protein binds to sulforaphane
sulforaphane results in increased expression of DES mRNA

PMID:21838287 PMID:30529165

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:76,850,982...76,858,699

G

deuterosome assembly protein 1

increases expression

sulforaphane results in increased expression of DEUP1 mRNA

NCBI chr 8:20,661,687...20,724,083
Ensembl chr 8:12,380,302...12,442,199

G

diacylglycerol O-acyltransferase 1

multiple interactions

sulforaphane inhibits the reaction [bisphenol A results in increased expression of DGAT1 mRNA]

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299

G

diacylglycerol O-acyltransferase 2

increases expression

sulforaphane results in increased expression of DGAT2 mRNA

NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428

G

DGCR8 microprocessor complex subunit

decreases expression

sulforaphane results in decreased expression of DGCR8 mRNA

NCBI chr11:96,208,959...96,241,560
Ensembl chr11:82,704,729...82,737,242

G

24-dehydrocholesterol reductase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DHCR24 mRNA

NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:121,344,575...121,371,137

G

dehydrogenase/reductase 11

increases expression
decreases expression

sulforaphane results in increased expression of DHRS11 mRNA
sulforaphane results in decreased expression of DHRS11 mRNA

PMID:30529165 PMID:31838189

NCBI chr10:70,195,637...70,205,735
Ensembl chr10:69,698,214...69,708,295

G

dehydrogenase/reductase 7C

increases expression

sulforaphane results in increased expression of DHRS7C mRNA

NCBI chr10:52,994,205...53,012,281
Ensembl chr10:52,495,262...52,513,338

G

DIM1 rRNA methyltransferase and ribosome maturation factor

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DIMT1 mRNA

NCBI chr 2:40,076,622...40,101,792
Ensembl chr 2:38,354,854...38,368,227

G

iodothyronine deiodinase 2

decreases expression

sulforaphane results in decreased expression of DIO2 mRNA

NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:109,665,523...109,679,809

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression
increases methylation

sulforaphane results in decreased expression of DKK1 mRNA
sulforaphane results in increased methylation of DKK1 gene

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 3

decreases expression

sulforaphane results in decreased expression of DKK3 mRNA

NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:166,238,238...166,280,590

G

dihydrolipoamide S-acetyltransferase

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DLAT mRNA
sulforaphane results in increased expression of DLAT mRNA

PMID:25450479 PMID:30529165

NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479

G

discs large MAGUK scaffold protein 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DLG1 mRNA

NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689

G

discs large MAGUK scaffold protein 3

decreases expression

sulforaphane results in decreased expression of DLG3 mRNA

NCBI chr X:69,899,694...69,951,928
Ensembl chr X:65,860,172...65,910,322

G

DLG associated protein 5

increases expression

sulforaphane results in increased expression of DLGAP5 mRNA

NCBI chr15:23,113,678...23,144,281
Ensembl chr15:20,633,966...20,664,518

G

delta like non-canonical Notch ligand 2

decreases expression

sulforaphane results in decreased expression of DLK2 mRNA

NCBI chr 9:22,174,667...22,179,149
Ensembl chr 9:14,676,562...14,681,594

G

distal-less homeobox 3

decreases expression

sulforaphane results in decreased expression of DLX3 mRNA

NCBI chr10:80,561,335...80,566,730
Ensembl chr10:80,064,489...80,069,872

G

distal-less homeobox 4

decreases expression

sulforaphane results in decreased expression of DLX4 mRNA

NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,085,465...80,090,456

G

distal membrane arm assembly component 2 like

decreases expression

sulforaphane results in decreased expression of DMAC2L mRNA

NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:88,205,700...88,223,933

G

dermokine

increases expression

sulforaphane results in increased expression of DMKN mRNA

NCBI chr 1:95,140,737...95,158,676
Ensembl chr 1:86,014,188...86,030,006

G

doublesex and mab-3 related transcription factor 2

increases expression

sulforaphane results in increased expression of DMRT2 mRNA

NCBI chr 1:232,743,935...232,750,431
Ensembl chr 1:223,317,642...223,324,131

G

cyclin D binding myb-like transcription factor 1

decreases expression

sulforaphane results in decreased expression of DMTF1 mRNA

NCBI chr 4:25,864,891...25,905,916
Ensembl chr 4:24,910,534...24,950,967

G

Dmx-like 2

decreases expression

sulforaphane results in decreased expression of DMXL2 mRNA

NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:54,741,160...54,885,161

G

dynein axonemal intermediate chain 3

increases expression

sulforaphane results in increased expression of DNAI3 mRNA

NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:234,929,677...235,006,173

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B13

increases expression

sulforaphane results in increased expression of DNAJB13 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:164,260,716...164,275,172
Ensembl chr 1:154,848,594...154,862,963

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

sulforaphane results in increased expression of DNAJB4 mRNA

NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member C15

increases expression

sulforaphane results in increased expression of DNAJC15 mRNA

NCBI chr15:59,594,314...59,658,862
Ensembl chr15:53,184,855...53,249,675

G

DnaJ heat shock protein family (Hsp40) member C17

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DNAJC17 mRNA

NCBI chr 3:126,616,043...126,649,599
Ensembl chr 3:106,162,197...106,195,751

G

dynamin 1-like

increases expression
multiple interactions

sulforaphane results in increased expression of DNM1L protein alternative form
sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of DNM1L protein]

PMID:27993529 PMID:37860845

NCBI chr11:98,084,049...98,135,663
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 1

decreases expression
multiple interactions

sulforaphane results in decreased expression of DNMT1 mRNA
sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT1 mRNA]; sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA]

PMID:24466240 PMID:30684530

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

increases expression

sulforaphane results in increased expression of DNMT3A mRNA

NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 beta

decreases expression
multiple interactions

sulforaphane results in decreased expression of DNMT3B mRNA
sulforaphane inhibits the reaction [DNMT3B protein binds to COMT promoter]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [DNMT3B protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT3B mRNA]

PMID:24466240 PMID:30684530

NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124

G

deoxynucleotidyltransferase, terminal, interacting protein 2

increases expression

sulforaphane results in increased expression of DNTTIP2 mRNA

NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:210,374,289...210,385,581

G

dedicator of cytokinesis 4

decreases expression

sulforaphane results in decreased expression of DOCK4 mRNA

NCBI chr 6:63,240,050...63,629,772
Ensembl chr 6:57,512,908...57,901,855

G

dedicator of cytokinesis 8

decreases expression

sulforaphane results in decreased expression of DOCK8 mRNA

NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:222,649,309...222,842,474

G

docking protein 7

increases expression

sulforaphane results in increased expression of DOK7 mRNA

NCBI chr14:79,890,051...79,924,081
Ensembl chr14:75,666,744...75,699,386

G

diphthamide biosynthesis 5

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DPH5 mRNA

NCBI chr 2:206,489,556...206,540,590
Ensembl chr 2:203,804,936...203,840,433

G

dihydropyrimidine dehydrogenase

increases expression

sulforaphane results in increased expression of DPYD mRNA

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982

G

DNA-damage regulated autophagy modulator 1

decreases expression

sulforaphane results in decreased expression of DRAM1 mRNA

NCBI chr 7:24,630,233...24,665,270
Ensembl chr 7:22,742,849...22,776,765

G

dynein regulatory complex subunit 12 homolog

increases expression

sulforaphane results in increased expression of CCDC153 mRNA

NCBI chr 8:53,468,344...53,481,168
Ensembl chr 8:44,577,836...44,584,338

G

dopamine receptor D1

multiple interactions

sulforaphane inhibits the reaction [Buthionine Sulfoximine results in decreased expression of DRD1 protein]

NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002

G

desmocollin 2

increases expression

sulforaphane results in increased expression of DSC2 mRNA

NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,450,390...11,482,392

G

desmoglein 2

increases expression

sulforaphane results in increased expression of DSG2 mRNA

NCBI chr18:12,121,287...12,179,590
Ensembl chr18:11,846,183...11,904,156

G

desmoplakin

increases expression

sulforaphane results in increased expression of DSP mRNA

NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,623,588...26,671,800

G

dual specificity phosphatase 10

decreases expression

sulforaphane results in decreased expression of DUSP10 mRNA

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 16

increases expression
decreases expression

sulforaphane results in increased expression of DUSP16 mRNA
sulforaphane results in decreased expression of DUSP16 mRNA

PMID:26833863 PMID:31838189

NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:167,548,155...167,629,980

G

dual specificity phosphatase 4

increases expression

sulforaphane results in increased expression of DUSP4 mRNA

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:57,377,229...57,398,138

G

dual specificity phosphatase 5

increases expression

sulforaphane results in increased expression of DUSP5 mRNA

NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 6

increases expression

sulforaphane results in increased expression of DUSP6 mRNA

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 8

decreases expression

sulforaphane results in decreased expression of DUSP8 mRNA

NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:197,169,422...197,182,921

G

dual specificity phosphatase 9

decreases expression

sulforaphane results in decreased expression of DUSP9 mRNA

NCBI chr X:156,503,237...156,507,162
Ensembl chr X:151,351,897...151,355,821

G

dynein cytoplasmic 1 heavy chain 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNC1H1 mRNA

NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:129,609,397...129,680,883

G

dynein 2 intermediate chain 2

decreases expression

sulforaphane results in decreased expression of DYNC2I2 mRNA

NCBI chr 3:33,703,882...33,719,960
Ensembl chr 3:13,306,039...13,322,121

G

dynein light chain Tctex-type 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNLT3 mRNA

NCBI chr X:16,000,425...16,009,632
Ensembl chr X:13,327,892...13,337,139

G

E2F transcription factor 1

decreases expression

sulforaphane results in decreased expression of E2F1 mRNA

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

increases methylation

sulforaphane results in increased methylation of E2F3 gene

NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,601,830...34,676,253

G

EBF transcription factor 2

increases expression

sulforaphane results in increased expression of EBF2 mRNA

NCBI chr15:45,610,949...45,809,828
Ensembl chr15:41,435,509...41,634,403

G

enoyl-CoA hydratase 1

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ECH1 mRNA
sulforaphane results in increased expression of ECH1 mRNA

PMID:25450479 PMID:30529165

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:84,112,751...84,120,795

G

endothelin receptor type A

decreases expression

sulforaphane results in decreased expression of EDNRA mRNA

NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049

G

eukaryotic translation elongation factor 1 alpha 2

increases expression

sulforaphane results in increased expression of EEF1A2 mRNA

NCBI chr 3:188,643,455...188,652,633
Ensembl chr 3:168,195,357...168,275,071

G

eukaryotic elongation factor-2 kinase

decreases expression

sulforaphane results in decreased expression of EEF2K mRNA

NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:175,393,154...175,455,164

G

EF-hand domain family, member D1

decreases expression

sulforaphane results in decreased expression of EFHD1 mRNA

NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:87,938,284...87,984,917

G

ephrin A1

decreases expression

sulforaphane results in decreased expression of EFNA1 mRNA

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:174,681,682...174,690,866

G

ephrin B2

decreases expression

sulforaphane results in decreased expression of EFNB2 mRNA

NCBI chr16:87,485,215...87,529,224
Ensembl chr16:80,783,417...80,824,391

G

EFR3 homolog B

decreases expression

sulforaphane results in decreased expression of EFR3B mRNA

NCBI chr 6:32,664,593...32,740,417
Ensembl chr 6:26,948,540...27,020,933

G

EGF-like-domain, multiple 6

decreases expression

sulforaphane results in decreased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

ets homologous factor

decreases expression

sulforaphane results in decreased expression of EHF mRNA

NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:89,641,833...89,679,997

G

EP300 interacting inhibitor of differentiation 3

increases expression

sulforaphane results in increased expression of EID3 mRNA

NCBI chr 7:22,747,645...22,748,967

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions
increases expression

sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]
sulforaphane results in increased expression of EIF2AK3 protein modified form

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 alpha kinase 4

decreases expression

sulforaphane results in decreased expression of EIF2AK4 mRNA

NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:105,356,261...105,441,630

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions
increases expression

sulforaphane inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2S1 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2S1 protein modified form]
sulforaphane results in increased expression of EIF2S1 protein modified form

PMID:22922937 PMID:36670177

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 4E family member 3

increases expression

sulforaphane results in increased expression of EIF4E3 mRNA

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

eukaryotic translation initiation factor 5

increases expression

sulforaphane results in increased expression of EIF5 mRNA

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 5A

affects binding

EIF5A protein binds to sulforaphane

NCBI chr10:55,138,821...55,143,272
Ensembl chr10:54,640,024...54,644,656

G

eukaryotic translation initiation factor 5A2

increases expression

sulforaphane results in increased expression of EIF5A2 mRNA

NCBI chr 2:113,656,748...113,674,598
Ensembl chr 2:111,729,323...111,746,087

G

E74 like ETS transcription factor 3

decreases expression

sulforaphane results in decreased expression of ELF3 mRNA

NCBI chr13:49,242,265...49,247,102
Ensembl chr13:46,690,466...46,695,481

G

extracellular leucine-rich repeat and fibronectin type III domain containing 1

decreases expression

sulforaphane results in decreased expression of ELFN1 mRNA

NCBI chr12:19,773,911...19,839,375
Ensembl chr12:14,660,083...14,724,580

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

decreases expression

sulforaphane results in decreased expression of ELFN2 mRNA

NCBI chr 7:112,101,998...112,153,280
Ensembl chr 7:110,225,919...110,272,433

G

elongation factor for RNA polymerase II 2

increases expression

sulforaphane results in increased expression of ELL2 mRNA

NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:5,189,971...5,258,781

G

ELOVL fatty acid elongase 6

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ELOVL6 mRNA
sulforaphane results in increased expression of ELOVL6 mRNA

PMID:25450479 PMID:31838189

NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186

G

epithelial membrane protein 2

decreases expression

sulforaphane results in decreased expression of EMP2 mRNA

NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,360,073...5,394,733

G

epithelial membrane protein 3

decreases expression

sulforaphane results in decreased expression of EMP3 mRNA

NCBI chr 1:105,525,086...105,528,370
Ensembl chr 1:96,388,652...96,391,988

G

ectodermal-neural cortex 1

increases expression

sulforaphane results in increased expression of ENC1 mRNA

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:28,550,464...28,562,713

G

endonuclease G

increases expression

sulforaphane results in increased expression of ENDOG protein

NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:13,449,086...13,451,932

G

enkurin, TRPC channel interacting protein

increases expression

sulforaphane results in increased expression of ENKUR mRNA

NCBI chr17:88,599,057...88,622,668
Ensembl chr17:83,690,797...83,714,408

G

enolase 3

decreases expression

sulforaphane results in decreased expression of ENO3 mRNA

NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,366,975...55,375,921

G

glutamyl aminopeptidase

decreases expression

sulforaphane results in decreased expression of ENPEP mRNA

NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression

sulforaphane results in decreased expression of ENPP2 mRNA

NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleoside triphosphate diphosphohydrolase 2

increases expression
decreases expression

sulforaphane results in increased expression of ENTPD2 mRNA
sulforaphane results in decreased expression of ENTPD2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:8,213,663...8,226,866

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

sulforaphane results in increased expression of ENTPD5 mRNA

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:104,019,185...104,055,530

G

endosomal transmembrane epsin interactor 1

decreases expression

sulforaphane results in decreased expression of ENTREP1 mRNA

NCBI chr 1:231,018,987...231,073,474
Ensembl chr 1:221,592,503...221,646,758

G

E1A binding protein p300

multiple interactions

sulforaphane inhibits the reaction [EP300 protein binds to COMT promoter]

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

erythrocyte membrane protein band 4.1-like 1

decreases expression

sulforaphane results in decreased expression of EPB41L1 mRNA

NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:144,984,640...145,052,721

G

erythrocyte membrane protein band 4.1 like 4A

decreases expression

sulforaphane results in decreased expression of EPB41L4A mRNA

NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,406,057...25,615,149

G

ependymin related 1

increases expression

sulforaphane results in increased expression of EPDR1 mRNA

NCBI chr17:50,029,591...50,054,254
Ensembl chr17:45,333,956...45,358,594

G

epithelial mitogen

increases expression

sulforaphane results in increased expression of EPGN mRNA

NCBI chr14:17,360,968...17,369,000
Ensembl chr14:17,076,774...17,084,806

G

Eph receptor A7

decreases expression

sulforaphane results in decreased expression of EPHA7 mRNA

NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:42,975,405...43,127,112

G

epoxide hydrolase 1

increases expression
multiple interactions

sulforaphane results in increased expression of EPHX1 mRNA
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA
sulforaphane promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer]
sulforaphane results in increased expression of EPHX1 exon; sulforaphane results in increased expression of EPHX1 mRNA; sulforaphane results in increased expression of EPHX1 protein; sulforaphane results in increased expression of EPHX1 protein alternative form

PMID:17942926 PMID:24704207 PMID:31838189

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 2

increases expression

sulforaphane results in increased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:40,289,902...40,327,615

G

ERCC excision repair 4, endonuclease catalytic subunit

increases expression

sulforaphane results in increased expression of ERCC4 mRNA

NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369

G

ERCC excision repair 5, endonuclease

increases expression

sulforaphane results in increased expression of ERCC5 mRNA

NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472

G

Ets2 repressor factor

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ERF mRNA

NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:80,829,935...80,838,388

G

ETS transcription factor ERG

decreases expression
multiple interactions

sulforaphane results in decreased expression of ERG mRNA; sulforaphane results in decreased expression of ERG protein
sulforaphane inhibits the reaction [AR protein binds to ERG enhancer]

NCBI chr11:48,148,149...48,370,472
Ensembl chr11:34,678,618...34,845,871

G

endoregulin

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ERLN mRNA
sulforaphane results in increased expression of ERLN mRNA

NCBI chr10:101,643,129...101,652,465

G

endoplasmic reticulum oxidoreductase 1 alpha

increases expression

sulforaphane results in increased expression of ERO1A protein

NCBI chr15:20,974,771...21,010,170
Ensembl chr15:18,492,945...18,530,478

G

ERBB receptor feedback inhibitor 1

decreases expression

sulforaphane results in decreased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:161,323,998...161,337,282

G

espin

decreases expression

sulforaphane results in decreased expression of ESPN mRNA

NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:162,626,560...162,660,256

G

estrogen receptor 1

multiple interactions

ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

extended synaptotagmin 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ESYT2 mRNA

NCBI chr 6:143,359,870...143,455,600
Ensembl chr 6:137,219,707...137,312,590

G

eukaryotic translation termination factor 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ETF1 mRNA

NCBI chr18:26,776,518...26,804,857
Ensembl chr18:26,504,080...26,530,810

G

electron transfer flavoprotein subunit alpha

increases expression

sulforaphane results in increased expression of ETFA mRNA

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:55,835,134...55,891,969

G

electron transfer flavoprotein subunit beta

increases expression

sulforaphane results in increased expression of ETFB mRNA

NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:93,851,858...93,866,068

G

electron transfer flavoprotein dehydrogenase

increases expression

sulforaphane results in increased expression of ETFDH mRNA

NCBI chr 2:167,038,707...167,060,758
Ensembl chr 2:164,729,749...164,762,745

G

ethanolamine kinase 2

decreases expression

sulforaphane results in decreased expression of ETNK2 mRNA

NCBI chr13:47,362,964...47,381,100
Ensembl chr13:44,811,015...44,829,037

G

ethanolamine-phosphate phospho-lyase

decreases expression

sulforaphane results in decreased expression of ETNPPL mRNA

NCBI chr 2:221,847,210...221,868,827
Ensembl chr 2:219,172,978...219,192,212

G

ETS proto-oncogene 2, transcription factor

decreases expression

sulforaphane results in decreased expression of ETS2 mRNA

NCBI chr11:48,491,057...48,507,843
Ensembl chr11:35,021,596...35,038,319

G

ETS variant transcription factor 4

increases expression

sulforaphane results in increased expression of ETV4 mRNA

NCBI chr10:87,206,977...87,222,202
Ensembl chr10:86,706,749...86,721,974

G

ETS variant transcription factor 5

decreases expression
increases expression

sulforaphane results in decreased expression of ETV5 mRNA
sulforaphane results in increased expression of ETV5 mRNA

PMID:30529165 PMID:31838189

NCBI chr11:92,113,171...92,170,758
Ensembl chr11:78,608,710...78,666,215

G

exocyst complex component 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EXOC1 mRNA

NCBI chr14:31,965,782...32,014,156
Ensembl chr14:31,611,547...31,659,914

G

exostosin glycosyltransferase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EXT2 mRNA

NCBI chr 3:100,120,776...100,253,424
Ensembl chr 3:79,665,415...79,798,059

G

EYA transcriptional coactivator and phosphatase 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EYA4 mRNA

NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:22,172,275...22,415,976

G

F11 receptor

decreases expression

sulforaphane results in decreased expression of F11R mRNA

NCBI chr13:86,406,229...86,429,819
Ensembl chr13:83,873,797...83,897,402

G

coagulation factor XII

decreases expression

sulforaphane results in decreased expression of F12 mRNA

NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530

G

coagulation factor XIII A1 chain

decreases expression

sulforaphane results in decreased expression of F13A1 mRNA

NCBI chr17:28,021,197...28,197,960
Ensembl chr17:27,815,702...27,992,700

G

coagulation factor III, tissue factor

increases expression

sulforaphane results in increased expression of F3 mRNA; sulforaphane results in increased expression of F3 protein

PMID:31838189 PMID:33814512

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor VII

decreases expression

sulforaphane results in decreased expression of F7 mRNA

NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610

G

fatty acid 2-hydroxylase

decreases expression

sulforaphane results in decreased expression of FA2H mRNA

NCBI chr19:56,222,240...56,273,480
Ensembl chr19:39,312,906...39,364,153

G

fatty acid binding protein 3

increases expression
decreases expression

sulforaphane results in increased expression of FABP3 mRNA
sulforaphane results in decreased expression of FABP3 mRNA

PMID:30529165 PMID:31838189

NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:142,651,956...142,658,718

G

fatty acid binding protein 4

increases expression

sulforaphane results in increased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

family with sequence similarity 13, member C

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FAM13C mRNA

NCBI chr20:18,064,706...18,186,888
Ensembl chr20:18,065,628...18,187,592

G

FAM161 centrosomal protein A

decreases expression

sulforaphane results in decreased expression of FAM161A mRNA

NCBI chr14:101,210,694...101,256,020
Ensembl chr14:97,009,491...97,028,588

G

family with sequence similarity 167, member B

decreases expression

sulforaphane results in decreased expression of FAM167B mRNA

NCBI chr 5:141,920,695...141,922,342
Ensembl chr 5:141,920,695...141,922,340

G

family with sequence similarity 216, member B

increases expression

sulforaphane results in increased expression of FAM216B mRNA

NCBI chr15:53,469,495...53,482,385
Ensembl chr15:53,469,599...53,482,398

G

family with sequence similarity 43, member A

increases expression

sulforaphane results in increased expression of FAM43A mRNA

NCBI chr11:83,633,165...83,636,313
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 72, member A

increases expression

sulforaphane results in increased expression of FAM72A mRNA

NCBI chr13:45,519,940...45,531,322
Ensembl chr13:42,967,578...42,984,208

G

family with sequence similarity 81, member A

increases expression

sulforaphane results in increased expression of FAM81A mRNA

NCBI chr 8:79,643,754...79,702,792
Ensembl chr 8:70,763,614...70,821,875

G

family with sequence similarity 83, member A

decreases expression

sulforaphane results in decreased expression of FAM83A mRNA

NCBI chr 7:91,412,366...91,436,819
Ensembl chr 7:89,522,826...89,547,388

G

family with sequence similarity 83, member E

increases expression

sulforaphane results in increased expression of FAM83E mRNA

NCBI chr 1:96,191,581...96,201,182
Ensembl chr 1:96,191,742...96,201,192

G

FA complementation group A

increases expression

sulforaphane results in increased expression of FANCA mRNA

NCBI chr19:68,210,562...68,271,080
Ensembl chr19:51,304,021...51,362,527

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases expression

sulforaphane results in decreased expression of FARP1 mRNA

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:98,182,329...98,363,299

G

Fas cell surface death receptor

increases expression

sulforaphane results in increased expression of FAS mRNA; sulforaphane results in increased expression of FAS protein

PMID:26833863 PMID:31838189

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

increases expression

sulforaphane results in increased expression of FASLG protein

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FASN mRNA
sulforaphane inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]

PMID:25450479 PMID:36670177

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

fibulin 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FBLN1 mRNA

NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:116,310,582...116,390,075

G

fibrillin 2

decreases expression

sulforaphane results in decreased expression of FBN2 mRNA

NCBI chr18:53,696,197...53,901,992
Ensembl chr18:51,499,737...51,703,976

G

F-box and leucine-rich repeat protein 12

decreases expression

sulforaphane results in decreased expression of FBXL12 mRNA

NCBI chr 8:27,453,042...27,459,136
Ensembl chr 8:19,160,352...19,183,607

G

F-box protein 11

decreases expression

sulforaphane results in decreased expression of FBXO11 mRNA

NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:6,486,015...6,562,662

G

F-box protein 2

decreases expression

sulforaphane results in decreased expression of FBXO2 mRNA

NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:158,592,925...158,598,355

G

F-box protein 32

decreases expression

sulforaphane results in decreased expression of FBXO32 mRNA

NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 4

decreases expression

sulforaphane results in decreased expression of FBXO4 mRNA

NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:53,174,798...53,187,792

G

Fc alpha receptor

increases expression

sulforaphane results in increased expression of FCAR mRNA

NCBI chr 1:78,669,119...78,703,223

G

FCH and mu domain containing endocytic adaptor 2

decreases expression

sulforaphane results in decreased expression of FCHO2 mRNA

NCBI chr 2:31,813,356...31,916,471
Ensembl chr 2:30,080,962...30,181,241

G

Fc mu receptor

increases expression

sulforaphane results in increased expression of FCMR mRNA

NCBI chr13:44,889,628...44,903,926
Ensembl chr13:42,337,414...42,351,653

G

ferrochelatase

increases expression

sulforaphane results in increased expression of FECH mRNA

NCBI chr18:60,215,325...60,248,525
Ensembl chr18:57,945,122...57,979,348

G

fetuin B

increases expression

sulforaphane results in increased expression of FETUB mRNA

NCBI chr11:91,586,750...91,599,789
Ensembl chr11:78,082,156...78,095,135

G

free fatty acid receptor 2

increases expression

sulforaphane results in increased expression of FFAR2 mRNA

NCBI chr 1:95,199,277...95,202,599
Ensembl chr 1:86,072,184...86,075,033

G

FYVE, RhoGEF and PH domain containing 6

decreases expression

sulforaphane results in decreased expression of FGD6 mRNA

NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:28,597,609...28,712,456

G

fibroblast growth factor 1

decreases expression

sulforaphane results in decreased expression of FGF1 mRNA

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor binding protein 1

decreases expression

sulforaphane results in decreased expression of FGFBP1 mRNA

NCBI chr14:71,316,171...71,319,965
Ensembl chr14:67,104,545...67,107,496

G

fibroblast growth factor receptor 3

decreases expression

sulforaphane results in decreased expression of FGFR3 mRNA

NCBI chr14:81,211,800...81,227,215
Ensembl chr14:76,987,993...77,003,341

G

fibrinogen-like 2

increases expression

sulforaphane results in increased expression of FGL2 mRNA

NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:13,710,575...13,716,207

G

four and a half LIM domains 1

decreases expression

sulforaphane results in decreased expression of FHL1 mRNA

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:134,555,479...134,614,928

G

four and a half LIM domains 2

decreases expression

sulforaphane results in decreased expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:45,388,981...45,431,192

G

formin homology 2 domain containing 3

increases expression

sulforaphane results in increased expression of FHOD3 mRNA

NCBI chr18:16,267,830...16,700,508
Ensembl chr18:15,993,324...16,425,796

G

folliculogenesis specific bHLH transcription factor

increases expression

sulforaphane results in increased expression of FIGLA mRNA

NCBI chr 4:119,989,983...119,994,217
Ensembl chr 4:118,432,765...118,436,690

G

fission, mitochondrial 1

increases expression

sulforaphane results in increased expression of FIS1 protein

NCBI chr12:25,345,239...25,360,135
Ensembl chr12:19,708,558...19,723,377

G

FLVCR choline and putative heme transporter 2

decreases expression

sulforaphane results in decreased expression of FLVCR2 mRNA

NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:105,408,339...105,472,353

G

fibronectin type III domain containing 3B

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FNDC3B mRNA

NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:110,312,694...110,547,830

G

fibronectin type III domain containing 5

increases expression
multiple interactions

sulforaphane results in increased expression of FNDC5 mRNA
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FNDC5 mRNA

NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:141,481,590...141,490,731

G

folate receptor alpha

decreases expression

sulforaphane results in decreased expression of FOLR1 mRNA

NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:156,219,460...156,230,667

G

folate receptor beta

increases expression

sulforaphane results in increased expression of FOLR2 mRNA

NCBI chr 1:165,612,047...165,630,382
Ensembl chr 1:156,200,060...156,205,724

G

FOS like 1, AP-1 transcription factor subunit

increases expression
increases methylation

sulforaphane results in increased expression of FOSL1 mRNA
sulforaphane results in increased methylation of FOSL1 gene

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box A3

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FOXA3 mRNA

NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box C2

decreases expression

sulforaphane results in decreased expression of FOXC2 mRNA

NCBI chr19:66,094,718...66,097,420
Ensembl chr19:49,185,662...49,188,737

G

forkhead box Q1

decreases expression

sulforaphane results in decreased expression of FOXQ1 mRNA

NCBI chr17:33,121,454...33,124,087
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377

G

formyl peptide receptor 1

increases expression

sulforaphane results in increased expression of FPR1 mRNA

NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:58,747,246...58,756,559

G

formyl peptide receptor 2

increases expression

sulforaphane results in increased expression of FPR2 mRNA

NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:58,776,752...58,786,019

G

Fraser extracellular matrix complex subunit 1

decreases expression

sulforaphane results in decreased expression of FRAS1 mRNA

NCBI chr14:13,095,370...13,506,895
Ensembl chr14:12,793,599...13,200,726

G

ferric-chelate reductase 1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FRRS1 mRNA

NCBI chr 2:207,505,786...207,566,376
Ensembl chr 2:204,823,025...204,895,540

G

ferritin heavy chain 1

increases expression

sulforaphane results in increased expression of FTH1 mRNA

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression

sulforaphane results in increased expression of FTL mRNA

NCBI chr 1:105,072,858...105,074,705
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

fucose mutarotase

increases expression

sulforaphane results in increased expression of FUOM mRNA

NCBI chr 1:204,318,180...204,322,690
Ensembl chr 1:194,886,709...194,893,046

G

FMR1 autosomal homolog 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FXR2 mRNA

NCBI chr10:54,849,345...54,869,713
Ensembl chr10:54,350,131...54,370,964

G

frizzled class receptor 7

increases expression

sulforaphane results in increased expression of FZD7 mRNA

NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:60,930,875...60,935,781

G

G3BP stress granule assembly factor 2

decreases methylation

sulforaphane results in decreased methylation of G3BP2 gene

NCBI chr14:16,216,684...16,304,828
Ensembl chr14:15,987,417...16,020,548

G

glucose-6-phosphate dehydrogenase

increases expression

sulforaphane results in increased expression of G6PD mRNA

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801

G

GRB2-associated binding protein 2

decreases expression

sulforaphane results in decreased expression of GAB2 mRNA

NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:151,429,695...151,625,031

G

GABA type A receptor associated protein like 1

increases expression

sulforaphane results in increased expression of GABARAPL1 mRNA

NCBI chr 4:164,666,332...164,675,474
Ensembl chr 4:162,980,249...162,989,450

G

GA binding protein transcription factor subunit beta 2

increases expression

sulforaphane results in increased expression of GABPB2 mRNA

NCBI chr 2:185,444,309...185,484,200
Ensembl chr 2:182,761,359...182,795,109

G

growth arrest and DNA-damage-inducible, alpha

increases expression

sulforaphane results in increased expression of GADD45A mRNA

PMID:17937621 PMID:26833863

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 12

increases expression

sulforaphane results in increased expression of GALNT12 mRNA

NCBI chr 5:66,180,171...66,208,931
Ensembl chr 5:61,384,571...61,413,354

G

polypeptide N-acetylgalactosaminyltransferase-like 6

decreases expression

sulforaphane results in decreased expression of GALNTL6 mRNA

NCBI chr16:36,203,674...37,454,709
Ensembl chr16:31,186,462...32,441,960

G

glycyl-tRNA synthetase 1

increases expression

sulforaphane results in increased expression of GARS1 mRNA

NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest-specific 1

decreases expression

sulforaphane results in decreased expression of GAS1 mRNA

NCBI chr17:4,487,716...4,490,701

G

growth arrest specific 7

increases expression

sulforaphane results in increased expression of GAS7 mRNA

NCBI chr10:52,651,690...52,882,244
Ensembl chr10:52,152,493...52,383,276

G

glutamyl-tRNA amidotransferase subunit C

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of GATC mRNA

NCBI chr12:46,930,820...46,938,790
Ensembl chr12:41,270,087...41,277,995

G

glycine amidinotransferase

decreases expression

sulforaphane results in decreased expression of GATM mRNA

NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:109,658,951...109,684,129

G

GTP cyclohydrolase I feedback regulator

decreases expression

sulforaphane results in decreased expression of GCHFR mRNA

NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:106,159,394...106,162,080

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
increases expression
decreases methylation
decreases expression

[sulforaphane co-treated with Acetaminophen] results in increased expression of GCLC mRNA; [sulforaphane co-treated with dibenzoylmethane] results in increased expression of GCLC mRNA; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLC mRNA]; sulforaphane inhibits the reaction [Acetaminophen results in decreased expression of GCLC mRNA]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]
alpha-methylepinine promotes the reaction [sulforaphane results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]; sulforaphane promotes the reaction [alpha-methylepinine results in increased expression of GCLC mRNA]; sulforaphane promotes the reaction [Cisplatin results in increased expression of GCLC mRNA]
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]
sulforaphane results in increased expression of GCLC mRNA; sulforaphane results in increased expression of GCLC protein
sulforaphane results in decreased methylation of GCLC gene
sulforaphane results in decreased expression of GCLC mRNA

PMID:17942926 PMID:19071154 PMID:19303893 PMID:20442190 PMID:20932822 More...

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

multiple interactions
increases expression
decreases expression

NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLM mRNA]; sulforaphane inhibits the reaction [Acetaminophen results in decreased expression of GCLM mRNA]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein]
sulforaphane results in increased expression of GCLM; sulforaphane results in increased expression of GCLM mRNA; sulforaphane results in increased expression of GCLM protein
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of GCLM protein]
sulforaphane results in decreased expression of GCLM mRNA

PMID:19071154 PMID:19303893 PMID:20442190 PMID:20932822 PMID:21539383 More...

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

sulforaphane results in increased expression of GCNT3 mRNA

NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:70,686,844...70,699,562

G

growth differentiation factor 11

decreases expression

sulforaphane results in decreased expression of GDF11 mRNA

NCBI chr 7:1,896,229...1,909,147
Ensembl chr 7:1,311,732...1,320,725

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases expression

sulforaphane results in decreased expression of GDPD5 mRNA

NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:153,679,718...153,761,446

G

GIPC PDZ domain containing family, member 3

decreases expression

sulforaphane results in decreased expression of GIPC3 mRNA

NCBI chr 7:9,026,905...9,034,005

G

gap junction protein, alpha 5

decreases expression

sulforaphane results in decreased expression of GJA5 mRNA

NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952

G

galactosidase, alpha

increases expression

sulforaphane results in increased expression of GLA mRNA

NCBI chr X:102,062,497...102,073,915
Ensembl chr X:97,768,996...97,780,664

G

galactosidase, beta 1-like 3

decreases expression

sulforaphane results in decreased expression of GLB1L3 mRNA

NCBI chr 8:33,454,914...33,496,641
Ensembl chr 8:25,179,165...25,220,904

G

glyoxalase 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein]
sulforaphane results in increased expression of GLO1 protein

NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,662,801...8,681,649

G

glutaredoxin

increases expression

sulforaphane results in increased expression of GLRX mRNA

NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:5,341,885...5,351,680

G

GDP-mannose 4, 6-dehydratase

decreases expression

sulforaphane results in decreased expression of GMDS mRNA

NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,095,386...32,621,961

G

geminin, DNA replication inhibitor

increases expression

sulforaphane results in increased expression of GMNN mRNA

NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,301,808...40,310,054

G

guanosine monophosphate reductase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of GMPR2 mRNA

NCBI chr15:33,135,455...33,144,923
Ensembl chr15:29,165,783...29,174,935

G

glucosamine-6-phosphate deaminase 1

increases expression

sulforaphane results in increased expression of GNPDA1 mRNA

NCBI chr18:30,416,599...30,428,630
Ensembl chr18:30,165,427...30,177,486

G

glycerol-3-phosphate acyltransferase 3

increases expression

sulforaphane results in increased expression of GPAT3 mRNA

PMID:26833863 PMID:31838189

NCBI chr14:9,018,762...9,072,552
Ensembl chr14:8,714,373...8,766,490

G

glypican 1

increases expression

sulforaphane results in increased expression of GPC1 mRNA

NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:93,396,234...93,424,047

G

glypican 5

decreases expression

sulforaphane results in decreased expression of GPC5 mRNA

NCBI chr15:98,614,499...100,051,285
Ensembl chr15:92,239,176...93,643,282

G

G protein-coupled estrogen receptor 1

decreases expression

sulforaphane results in decreased expression of GPER1 mRNA

NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

sulforaphane results in decreased expression of GPLD1 mRNA

NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939

G

glycoprotein m6b

decreases expression

sulforaphane results in decreased expression of GPM6B mRNA

NCBI chr X:31,689,485...31,836,199
Ensembl chr X:28,059,450...28,204,211

G

G protein-coupled receptor 135

increases expression

sulforaphane results in increased expression of GPR135 mRNA

NCBI chr 6:96,363,466...96,366,594
Ensembl chr 6:90,629,178...90,630,551

G

G protein-coupled receptor 137C

decreases expression

sulforaphane results in decreased expression of GPR137C mRNA

NCBI chr15:20,905,923...20,972,318
Ensembl chr15:18,426,223...18,490,807

G

G protein-coupled receptor 153

decreases expression

sulforaphane results in decreased expression of GPR153 mRNA

NCBI chr 5:168,064,134...168,075,697
Ensembl chr 5:162,781,587...162,792,971

G

G protein-coupled receptor 22

increases expression

sulforaphane results in increased expression of GPR22 mRNA

NCBI chr 6:54,037,998...54,044,994
Ensembl chr 6:48,310,505...48,317,486

G

G protein-coupled receptor 3

increases expression

sulforaphane results in increased expression of GPR3 mRNA

NCBI chr 5:150,695,406...150,698,526
Ensembl chr 5:145,411,510...145,414,590

G

G protein-coupled receptor 37-like 1

decreases expression

sulforaphane results in decreased expression of GPR37L1 mRNA

NCBI chr13:49,150,355...49,157,204
Ensembl chr13:46,598,578...46,605,421

G

G-protein coupled receptor 65

decreases expression

sulforaphane results in decreased expression of GPR65 mRNA

NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:117,515,648...117,536,512

G

G protein-coupled receptor 84

increases expression

sulforaphane results in increased expression of GPR84 mRNA

NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178

G

G protein-coupled receptor 85

decreases expression

sulforaphane results in decreased expression of GPR85 mRNA

NCBI chr 4:43,070,194...43,075,662
Ensembl chr 4:42,102,941...42,109,566

G

G protein-coupled receptor, class C, group 5, member A

decreases expression

sulforaphane results in decreased expression of GPRC5A mRNA

NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:167,903,542...167,922,260

G

G protein-coupled receptor, class C, group 5, member B

decreases expression

sulforaphane results in decreased expression of GPRC5B mRNA

NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:173,316,907...173,340,932

G

G protein regulated inducer of neurite outgrowth 2

decreases expression

sulforaphane results in decreased expression of GPRIN2 mRNA

NCBI chr16:9,502,697...9,518,901
Ensembl chr16:9,505,643...9,507,010

G

G-protein signaling modulator 3

decreases expression

sulforaphane results in decreased expression of GPSM3 mRNA

NCBI chr20:4,161,730...4,163,591
Ensembl chr20:4,157,123...4,159,035

G

glutamic--pyruvic transaminase

multiple interactions

sulforaphane inhibits the reaction [Acetaminophen results in increased activity of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutamic--pyruvic transaminase 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of GPT2 mRNA

NCBI chr19:37,700,023...37,734,551
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 1

decreases expression

sulforaphane results in decreased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression

sulforaphane results in increased expression of GPX2 mRNA

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

decreases expression
increases expression
multiple interactions

sulforaphane results in decreased expression of GPX4 mRNA
sulforaphane results in increased expression of GPX4 protein
sulforaphane inhibits the reaction [Busulfan results in decreased expression of and results in decreased activity of GPX4 protein]

PMID:31838189 PMID:32416107

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982

G

GRAM domain containing 2B

decreases expression

sulforaphane results in decreased expression of GRAMD2B mRNA

NCBI chr18:52,082,128...52,180,056
Ensembl chr18:49,884,014...49,981,953

G

growth factor receptor bound protein 10

increases expression

sulforaphane results in increased expression of GRB10 mRNA

NCBI chr14:90,708,653...90,816,399
Ensembl chr14:86,495,054...86,602,806

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

sulforaphane results in decreased expression of GRIA3 mRNA

NCBI chr X:125,103,975...125,369,690
Ensembl chr X:120,238,534...120,504,096

G

glycogen synthase kinase 3 beta

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein]; sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646

G

gelsolin

increases methylation
decreases expression

sulforaphane results in increased methylation of GSN gene
sulforaphane results in decreased expression of GSN mRNA

NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402

G

glutathione-disulfide reductase

decreases activity
increases expression
increases activity
multiple interactions

sulforaphane results in decreased activity of GSR protein
sulforaphane results in increased expression of GSR mRNA
sulforaphane results in increased activity of GSR protein
sulforaphane inhibits the reaction [Oxidopamine results in decreased activity of GSR protein]

PMID:17937621 PMID:19303893 PMID:22664424 PMID:23518299 PMID:26833863 More...

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

multiple interactions
decreases expression
increases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA]; SN50 peptide inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA]
sulforaphane results in decreased expression of GSTA1 mRNA
sulforaphane results in increased expression of GSTA1 mRNA; sulforaphane results in increased expression of GSTA1 protein

PMID:11264000 PMID:12151360 PMID:12756216 PMID:12949046 PMID:15090468 More...

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

multiple interactions
increases expression

Hydrocortisone inhibits the reaction [sulforaphane results in increased expression of GSTA2 mRNA]

PMID:11264000 PMID:22606287

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase mu 1

multiple interactions
affects metabolic processing
affects response to substance
increases expression

sulforaphane inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]
GSTM1 protein affects the metabolism of sulforaphane
GSTM1 gene polymorphism affects the susceptibility to sulforaphane
sulforaphane results in increased expression of GSTM1 protein
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GSTM1 mRNA]; sulforaphane inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]
sulforaphane results in increased expression of GSTM1 mRNA; sulforaphane results in increased expression of GSTM1 protein

PMID:7826396 PMID:11309284 PMID:15623468 PMID:16905640 PMID:17942926 More...

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase, mu 5

multiple interactions
increases expression

[sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNA
sulforaphane results in increased expression of GSTM3 mRNA

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase omega 1

increases expression

sulforaphane results in increased expression of GSTO1 mRNA

NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:246,721,221...246,731,468

G

glutathione S-transferase pi 1

affects metabolic processing
decreases activity
multiple interactions
affects binding
increases expression

GSTP1 protein affects the metabolism of sulforaphane
sulforaphane results in decreased activity of GSTP1 protein
[sulforaphane promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; [sulforaphane promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforaphane results in increased expression of GSTP1 mRNA]; sulforaphane inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GSTP1 mRNA]; sulforaphane promotes the reaction [JUN protein binds to GSTP1 enhancer]; sulforaphane promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; sulforaphane results in increased expression of and results in increased activity of GSTP1 protein
GSTP1 protein binds to sulforaphane
NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GSTP1 mRNA]
sulforaphane results in increased expression of GSTP1 mRNA; sulforaphane results in increased expression of GSTP1 protein

PMID:7826396 PMID:17937621 PMID:19303893 PMID:20237067 PMID:20932822 More...

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

decreases expression
increases expression
multiple interactions

sulforaphane results in decreased expression of GSTT1 mRNA
sulforaphane analog results in increased expression of GSTT1 protein
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of GSTT1 mRNA

PMID:9855024 PMID:20442190 PMID:30529165

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585

G

GTP binding protein 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of GTPBP4 mRNA

NCBI chr17:65,997,472...66,019,530
Ensembl chr17:61,308,014...61,418,009

G

glucoside xylosyltransferase 2

decreases expression

sulforaphane results in decreased expression of GXYLT2 mRNA

PMID:26833863 PMID:31838189

NCBI chr 4:134,903,595...135,006,066
Ensembl chr 4:133,347,499...133,449,454

G

H1.0 linker histone

decreases expression

sulforaphane results in decreased expression of H1-0 mRNA

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:110,592,208...110,594,694

G

H2A clustered histone 1

affects binding

H2AC1 protein binds to sulforaphane

NCBI chr17:41,599,195...41,599,672
Ensembl chr17:41,135,489...41,172,022

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

sulforaphane results in increased expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869

G

hepcidin antimicrobial peptide

multiple interactions

sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of HAMP mRNA]
[sulforaphane co-treated with Aflatoxin B1] affects the expression of HAMP mRNA

PMID:21303654 PMID:25450479

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891

G

hepatitis A virus cellular receptor 1

multiple interactions

sulforaphane inhibits the reaction [Methamphetamine results in increased expression of HAVCR1 protein]

NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698

G

HCK proto-oncogene, Src family tyrosine kinase

increases expression

sulforaphane results in increased expression of HCK mRNA

NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:141,571,587...141,614,693

G

histone deacetylase 1

decreases expression
multiple interactions

sulforaphane results in decreased expression of HDAC1 mRNA
sulforaphane inhibits the reaction [Estradiol promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in increased expression of HDAC1 mRNA]; sulforaphane inhibits the reaction [Genistein promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [HDAC1 protein binds to COMT promoter]

NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:141,853,989...141,881,111

G

histone deacetylase 11

decreases expression

sulforaphane results in decreased expression of HDAC11 mRNA

NCBI chr 4:125,203,044...125,224,584
Ensembl chr 4:123,650,157...123,667,405

G

histone deacetylase 2

decreases expression
multiple interactions

sulforaphane results in decreased expression of HDAC2 mRNA
[Genistein co-treated with sulforaphane] results in decreased expression of HDAC2 mRNA

PMID:29899271 PMID:30684530

NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609

G

histone deacetylase 3

multiple interactions
decreases expression

NFE2L2 protein affects the reaction [sulforaphane affects the reaction [1,2-Dimethylhydrazine affects the expression of HDAC3 protein]]; sulforaphane affects the reaction [1,2-Dimethylhydrazine affects the expression of HDAC3 protein]
sulforaphane results in decreased expression of HDAC3 protein
[Genistein co-treated with sulforaphane] results in decreased expression of HDAC3 mRNA

PMID:26388957 PMID:29899271

NCBI chr18:30,021,847...30,041,061
Ensembl chr18:29,770,636...29,793,856

G

histone deacetylase 5

decreases expression

sulforaphane results in decreased expression of HDAC5 mRNA

NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,152,978...87,188,235

G

histone deacetylase 6

multiple interactions
decreases activity

HDAC6 protein inhibits the reaction [sulforaphane results in decreased expression of AR protein]; sulforaphane inhibits the reaction [Estradiol results in increased expression of HDAC6 mRNA]; sulforaphane inhibits the reaction [Genistein results in increased expression of HDAC6 mRNA]
sulforaphane results in decreased activity of HDAC6 protein

PMID:19805354 PMID:30684530

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:14,551,044...14,572,441

G

histone deacetylase 9

decreases expression

sulforaphane results in decreased expression of HDAC9 mRNA

NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:50,763,590...51,625,333

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

increases expression

sulforaphane results in increased expression of HECW1 mRNA

NCBI chr17:55,366,904...55,780,028
Ensembl chr17:50,670,954...51,080,720

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

decreases expression

sulforaphane results in decreased expression of HECW2 mRNA

NCBI chr 9:62,853,904...63,247,472
Ensembl chr 9:55,365,203...55,580,327

G

HEPACAM family member 2

decreases expression

sulforaphane results in decreased expression of HEPACAM2 mRNA

NCBI chr 4:31,446,195...31,480,859
Ensembl chr 4:31,446,169...31,480,953

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

increases expression

sulforaphane results in increased expression of HERC6 mRNA

NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:87,524,493...87,581,744

G

homocysteine inducible ER protein with ubiquitin like domain 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of HERPUD1 mRNA

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 2

decreases expression

sulforaphane results in decreased expression of HES2 mRNA

NCBI chr 5:167,947,948...167,964,660
Ensembl chr 5:162,667,190...162,668,235

G

hes-related family bHLH transcription factor with YRPW motif 1

decreases expression

sulforaphane results in decreased expression of HEY1 mRNA

NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:93,095,498...93,100,312

G

hedgehog acyltransferase-like

increases expression

sulforaphane results in increased expression of HHATL mRNA

NCBI chr 8:130,324,510...130,331,580
Ensembl chr 8:121,447,002...121,454,001

G

hematopoietically expressed homeobox

increases expression

sulforaphane results in increased expression of HHEX mRNA

NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:235,190,455...235,196,042

G

Hedgehog-interacting protein

decreases expression

sulforaphane results in decreased expression of HHIP mRNA

NCBI chr19:44,768,038...44,856,878
Ensembl chr19:27,863,213...27,952,528

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

sulforaphane results in increased expression of HIBCH mRNA

NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:48,590,099...48,669,824

G

HIC ZBTB transcriptional repressor 2

increases expression

sulforaphane results in increased expression of HIC2 mRNA

NCBI chr11:97,241,308...97,294,429
Ensembl chr11:83,738,874...83,767,484

G

hypoxia inducible factor 1 subunit alpha

decreases expression

sulforaphane results in decreased expression of HIF1A protein

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261

G

HIG1 hypoxia inducible domain family, member 1C

decreases expression

sulforaphane results in decreased expression of HIGD1C mRNA

NCBI chr 7:133,356,525...133,377,172
Ensembl chr 7:131,478,519...131,498,214

G

HIVEP zinc finger 3

decreases expression

sulforaphane results in decreased expression of HIVEP3 mRNA

NCBI chr 5:138,610,592...139,013,058
Ensembl chr 5:133,658,052...133,727,795

G

hexokinase domain containing 1

increases expression

sulforaphane results in increased expression of HKDC1 mRNA

NCBI chr20:30,878,037...30,917,044
Ensembl chr20:30,335,628...30,373,867

G

high mobility group AT-hook 2

increases expression

sulforaphane results in increased expression of HMGA2 mRNA

NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:55,880,112...55,994,784

G

high mobility group box 1

increases methylation

sulforaphane results in increased methylation of HMG1 gene

NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

hyaluronan-mediated motility receptor

decreases methylation
increases expression

sulforaphane results in decreased methylation of HMMR gene
sulforaphane results in increased expression of HMMR mRNA

NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,132,977...25,163,060

G

heme oxygenase 1

multiple interactions
increases expression
increases activity
decreases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; 3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; cyanoginosin LR promotes the reaction [sulforaphane results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; Estradiol inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1]; Reactive Oxygen Species affects the reaction [sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of HMOX1 protein]]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of HMOX1 mRNA]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of HMOX1 mRNA]; sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of HMOX1 protein]; sulforaphane results in increased expression of and results in increased activity of HMOX1 protein; Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; [sulforaphane co-treated with Dibutyl Phthalate] results in increased expression of HMOX1 protein; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1 protein]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [fenamidone results in increased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Trichloroethylene results in decreased expression of HMOX1 protein]; sulforaphane promotes the reaction [Acetaminophen results in increased expression of HMOX1 mRNA]; sulforaphane promotes the reaction [Methamphetamine results in increased expression of HMOX1 protein]
sulforaphane results in increased activity of HMOX1 protein
sulforaphane analog results in increased expression of HMOX1 protein; sulforaphane metabolite results in increased expression of HMOX1 mRNA; sulforaphane results in increased expression of HMOX1 mRNA; sulforaphane results in increased expression of HMOX1 protein
sulforaphane results in increased expression of HMOX1; sulforaphane results in increased expression of HMOX1 mRNA; sulforaphane results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; [Buthionine Sulfoximine co-treated with sulforaphane] results in increased expression of HMOX1 protein; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]
sulforaphane results in decreased expression of HMOX1 protein

PMID:16890772 PMID:18417180 PMID:18619545 PMID:19033392 PMID:19071154 More...

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein C

increases methylation

sulforaphane results in increased methylation of HNRNPC gene

NCBI chr15:27,253,098...27,282,779
Ensembl chr15:24,779,450...24,809,183

G

heterogeneous nuclear ribonucleoprotein F

affects binding

HNRNPF protein binds to sulforaphane

NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:151,083,062...151,109,038

G

heterogeneous nuclear ribonucleoprotein H1

affects binding

HNRNPH1 protein binds to sulforaphane

NCBI chr10:35,187,412...35,203,909
Ensembl chr10:34,693,555...34,702,846

G

heterogeneous nuclear ribonucleoprotein K

affects binding

HNRNPK protein binds to sulforaphane

NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,262,998...6,274,997

G

heterogeneous nuclear ribonucleoprotein L

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of HNRNPL mRNA

NCBI chr 1:93,226,373...93,239,084
Ensembl chr 1:84,100,879...84,111,553

G

heterogeneous nuclear ribonucleoprotein L-like

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of HNRNPLL mRNA

NCBI chr 6:20,720,013...20,752,803
Ensembl chr 6:14,970,057...14,999,745

G

4-hydroxy-2-oxoglutarate aldolase 1

decreases expression

sulforaphane results in decreased expression of HOGA1 mRNA

NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:240,857,126...240,884,568

G

homeo box C4

decreases expression

sulforaphane results in decreased expression of HOXC4 mRNA

NCBI chr 7:136,049,059...136,051,601
Ensembl chr 7:134,170,591...134,173,133

G

homeo box C6

decreases expression

sulforaphane results in decreased expression of HOXC6 mRNA

NCBI chr 7:136,013,679...136,051,601
Ensembl chr 7:134,135,502...134,148,392

G

haptoglobin

increases expression

sulforaphane results in increased expression of HP mRNA

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523

G

15-hydroxyprostaglandin dehydrogenase

decreases expression

sulforaphane results in decreased expression of HPGD mRNA

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:33,986,266...34,024,228

G

hematopoietic prostaglandin D synthase

decreases expression

sulforaphane results in decreased expression of HPGDS mRNA

NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:94,373,342...94,397,883

G

heparanase

increases expression
decreases expression

sulforaphane results in increased expression of HPSE mRNA
sulforaphane results in decreased expression of HPSE mRNA

PMID:26833863 PMID:31838189

NCBI chr14:9,200,971...9,241,377
Ensembl chr14:8,896,593...8,937,010

G

HR, lysine demethylase and nuclear receptor corepressor

decreases expression

sulforaphane results in decreased expression of HR mRNA

NCBI chr15:52,036,540...52,056,019
Ensembl chr15:45,626,835...45,646,313

G

histidine rich calcium binding protein

increases expression

sulforaphane results in increased expression of HRC mRNA

NCBI chr 1:104,949,750...104,953,475
Ensembl chr 1:95,813,253...95,816,984

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]]

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687

G

heat shock transcription factor 1

increases activity

sulforaphane results in increased activity of HSF1 protein

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 alpha family class A member 1

multiple interactions
increases acetylation
increases expression

sulforaphane inhibits the reaction [HSP90AA1 protein binds to AR protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of HSP90AA1 protein]
sulforaphane results in increased acetylation of HSP90AA1 protein
sulforaphane results in increased expression of HSP90AA1 mRNA

PMID:19805354 PMID:22922937 PMID:31838189

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 beta family member 1

decreases expression

sulforaphane results in decreased expression of HSP90B1 protein

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 13

increases expression

sulforaphane results in increased expression of HSPA13 mRNA

NCBI chr11:27,862,717...27,876,898
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 1B

increases expression

sulforaphane results in increased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 1 like

affects binding

HSPA1L protein binds to sulforaphane

NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571

G

heat shock protein family A (Hsp70) member 2

decreases expression

sulforaphane results in decreased expression of HSPA2 mRNA

NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:95,128,350...95,131,287

G

heat shock protein family A (Hsp70) member 4

affects binding

HSPA4 protein binds to sulforaphane

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family A (Hsp70) member 5

multiple interactions

sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 9

affects binding

HSPA9 protein binds to sulforaphane

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family B (small) member 3

decreases expression

sulforaphane results in decreased expression of HSPB3 mRNA

NCBI chr 2:47,028,451...47,029,165
Ensembl chr 2:45,295,053...45,296,145

G

heat shock protein family B (small) member 7

increases expression
decreases expression

sulforaphane results in increased expression of HSPB7 mRNA
sulforaphane results in decreased expression of HSPB7 mRNA

PMID:30529165 PMID:31838189

NCBI chr 5:159,010,759...159,014,245
Ensembl chr 5:153,727,588...153,731,266

G

heat shock protein family D (Hsp60) member 1

affects binding

HSPD1 protein binds to sulforaphane

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662

G

heat shock protein family H (Hsp110) member 1

increases expression

sulforaphane results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:5,390,922...5,410,224

G

HtrA serine peptidase 3

increases expression

sulforaphane results in increased expression of HTRA3 mRNA

NCBI chr14:79,293,535...79,321,936
Ensembl chr14:75,068,917...75,097,315

G

intercellular adhesion molecule 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]
sulforaphane results in increased expression of ICAM1 mRNA
sulforaphane inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; sulforaphane inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]

PMID:16890772 PMID:24967692 PMID:26833863 PMID:33894213 PMID:35724838

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

intercellular adhesion molecule 2

decreases expression

sulforaphane results in decreased expression of ICAM2 mRNA

NCBI chr10:91,808,449...91,819,319
Ensembl chr10:91,308,538...91,315,293

G

inhibitor of DNA binding 2

decreases expression

sulforaphane results in decreased expression of ID2 mRNA

NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400

G

inhibitor of DNA binding 3

decreases expression

sulforaphane results in decreased expression of ID3 mRNA

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

increases expression

sulforaphane results in increased expression of IDH3A mRNA

NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:54,971,740...54,991,084

G

interferon, alpha-inducible protein 27 like 2A

increases expression

sulforaphane results in increased expression of IFI27L2A mRNA

NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360

G

IFI30, lysosomal thiol reductase

increases expression

sulforaphane results in increased expression of IFI30 mRNA

NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,675,613...18,681,175

G

interferon-induced protein 44

increases expression

sulforaphane results in increased expression of IFI44 mRNA

NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:240,626,066...240,643,844

G

interferon induced with helicase C domain 1

increases expression

sulforaphane results in increased expression of IFIH1 mRNA

NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456

G

interferon-induced protein with tetratricopeptide repeats 2

increases expression

sulforaphane results in increased expression of IFIT2 mRNA

PMID:26833863 PMID:31838189

NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:232,102,570...232,108,635

G

interferon-induced protein with tetratricopeptide repeats 3

increases expression

sulforaphane results in increased expression of IFIT3 mRNA

NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 2

decreases expression

sulforaphane results in decreased expression of IFITM2 mRNA

NCBI chr 1:205,481,168...205,482,348
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

decreases expression

sulforaphane results in decreased expression of IFITM3 mRNA

NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:196,111,043...196,112,203

G

interferon gamma

multiple interactions
decreases activity

sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IFNG protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of NFKB1 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Dinoprostone]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Hydrogen Peroxide]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased phosphorylation of NFKBIA protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CASP1 protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of ITGAM protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NLRP3 protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PYCARD protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; sulforaphane inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; tin protoporphyrin IX inhibits the reaction [sulforaphane inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]
sulforaphane results in decreased activity of IFNG protein
sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Dinoprostone]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]

PMID:19071154 PMID:23942037 PMID:33007382 PMID:36988325

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

intraflagellar transport 81

increases expression

sulforaphane results in increased expression of IFT81 mRNA

NCBI chr12:39,618,559...39,697,971
Ensembl chr12:33,957,806...34,037,057

G

insulin-like growth factor 2 receptor

increases expression

sulforaphane results in increased expression of IGF2R mRNA

NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of IGFBP4 mRNA

NCBI chr10:84,491,471...84,503,487
Ensembl chr10:83,989,591...84,007,225

G

immunoglobulin-like and fibronectin type III domain containing 1

increases expression

sulforaphane results in increased expression of IGFN1 mRNA

NCBI chr13:49,947,330...49,979,203
Ensembl chr13:47,395,595...47,437,879

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

increases expression

sulforaphane results in increased expression of IKBKG mRNA

NCBI chr X:157,358,279...157,397,563
Ensembl chr X:152,216,596...152,239,499

G

IKAROS family zinc finger 2

decreases expression

sulforaphane results in decreased expression of IKZF2 mRNA

NCBI chr 9:78,495,670...78,640,896
Ensembl chr 9:71,042,440...71,190,867

G

interleukin 10

multiple interactions

sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 protein]

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 11

increases expression

sulforaphane results in increased expression of IL11 mRNA

NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 12B

multiple interactions

NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]
sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of IL12B mRNA]

PMID:16890772 PMID:33930529

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903

G

interleukin 18 receptor 1

increases expression

sulforaphane results in increased expression of IL18R1 mRNA

NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:42,727,869...42,760,715

G

interleukin 18 receptor accessory protein

increases expression

sulforaphane results in increased expression of IL18RAP mRNA

NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:42,768,220...42,800,959

G

interleukin 1 beta

multiple interactions
decreases activity
increases expression
decreases expression

[Eugenol results in increased activity of sulforaphane] which results in decreased expression of IL1B; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of IL1B; sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of IL1B mRNA]; sulforaphane inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; sulforaphane inhibits the reaction [IL1B protein affects the localization of RELA protein]; sulforaphane inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; sulforaphane inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of IL1B protein]; sulforaphane inhibits the reaction [Vehicle Emissions analog results in increased expression of IL1B protein]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of IL1B mRNA]; tin protoporphyrin IX inhibits the reaction [sulforaphane inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of IL1B protein]]
sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of NFKB1 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Dinoprostone]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Hydrogen Peroxide]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased phosphorylation of NFKBIA protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B protein]; sulforaphane inhibits the reaction [ochratoxin A results in increased expression of IL1B mRNA]
sulforaphane results in decreased activity of IL1B protein
sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Dinoprostone]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]
sulforaphane results in increased expression of IL1B mRNA
sulforaphane metabolite results in decreased expression of IL1B mRNA; sulforaphane results in decreased expression of IL1B mRNA

PMID:16905640 PMID:19071154 PMID:21382956 PMID:26833863 PMID:28710020 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

increases expression
decreases expression

sulforaphane results in increased expression of IL1R1 mRNA
sulforaphane results in decreased expression of IL1R1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 2

multiple interactions

sulforaphane results in decreased expression of and results in decreased secretion of IL2 protein

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 33

decreases expression

sulforaphane results in decreased expression of IL33 mRNA

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 3 receptor subunit alpha

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of IL3RA mRNA

NCBI chr12:21,431,848...21,437,336
Ensembl chr12:16,318,081...16,323,484

G

interleukin 4

multiple interactions

sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 protein]

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750

G

interleukin 4 receptor

increases expression

sulforaphane results in increased expression of IL4R mRNA

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 6

multiple interactions
decreases expression

sulforaphane inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of IL6 mRNA]; sulforaphane inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [Norepinephrine results in increased expression of and results in increased secretion of IL6 protein]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL6 protein]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of IL6 mRNA]
sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 protein]; sulforaphane inhibits the reaction [Cyclosporine results in increased expression of IL6 mRNA]; sulforaphane inhibits the reaction [ochratoxin A results in increased expression of IL6 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of IL6 mRNA]
NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]]; sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]
sulforaphane metabolite results in decreased expression of IL6 mRNA; sulforaphane results in decreased expression of IL6 mRNA

PMID:18636164 PMID:23958496 PMID:25305463 PMID:28710020 PMID:31173751 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

internexin neuronal intermediate filament protein, alpha

affects binding

INA protein binds to sulforaphane

NCBI chr 1:255,838,129...255,849,680
Ensembl chr 1:245,896,775...245,908,330

G

innate immunity activator

decreases expression

sulforaphane results in decreased expression of INAVA mRNA

NCBI chr13:50,218,149...50,238,430
Ensembl chr13:47,666,447...47,686,729

G

inhibin subunit alpha

decreases expression

sulforaphane results in decreased expression of INHA mRNA

NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:76,993,589...76,997,248

G

inhibin subunit beta B

increases expression

sulforaphane results in increased expression of INHBB mRNA

NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832

G

inositol polyphosphate-1-phosphatase

increases expression

sulforaphane results in increased expression of INPP1 mRNA

NCBI chr 9:56,161,816...56,209,774
Ensembl chr 9:48,669,901...48,717,793

G

inositol polyphosphate-5-phosphatase J

decreases expression

sulforaphane results in decreased expression of INPP5J mRNA

NCBI chr14:82,597,789...82,608,930
Ensembl chr14:78,374,161...78,385,326

G

insulin 1

multiple interactions

sulforaphane inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]
sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions

sulforaphane inhibits the reaction [INS protein results in increased phosphorylation of RPS6 protein]

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775

G

insulin-like 6

increases expression

sulforaphane results in increased expression of INSL6 mRNA

NCBI chr 1:236,483,530...236,487,065
Ensembl chr 1:227,069,958...227,073,493

G

interaction protein for cytohesin exchange factors 1

increases expression

sulforaphane results in increased expression of IPCEF1 mRNA

NCBI chr 1:45,654,252...45,857,045
Ensembl chr 1:43,269,202...43,427,969

G

IQ motif containing G

increases expression

sulforaphane results in increased expression of IQCG mRNA

NCBI chr11:81,235,204...81,276,249
Ensembl chr11:67,730,247...67,771,168

G

interleukin-1 receptor-associated kinase 4

multiple interactions

sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of IRAK4 protein]

NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:125,682,488...125,717,837

G

interferon regulatory factor 7

decreases expression

sulforaphane results in decreased expression of IRF7 mRNA

NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832

G

interferon regulatory factor 8

decreases expression

sulforaphane results in decreased expression of IRF8 mRNA

NCBI chr19:65,699,284...65,721,066
Ensembl chr19:48,790,588...48,811,829

G

insulin receptor substrate 2

decreases expression

sulforaphane results in decreased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482

G

interferon stimulated exonuclease gene 20

increases expression

sulforaphane results in increased expression of ISG20 mRNA

NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:132,815,123...132,837,027

G

immunoglobulin superfamily containing leucine-rich repeat

increases expression

sulforaphane results in increased expression of ISLR mRNA

NCBI chr 8:67,467,013...67,469,989
Ensembl chr 8:58,570,777...58,574,130

G

integrin subunit alpha 2

increases expression

sulforaphane results in increased expression of ITGA2 mRNA

NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 6

increases expression

sulforaphane results in increased expression of ITGA6 mRNA

NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:56,617,268...56,689,428

G

integrin subunit alpha M

increases expression
multiple interactions

sulforaphane results in increased expression of ITGAM mRNA
sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of ITGAM protein]

PMID:26833863 PMID:36988325

NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503

G

integrin subunit alpha X

increases expression

sulforaphane results in increased expression of ITGAX mRNA

NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:182,719,609...182,740,698

G

integrin subunit beta 2

increases expression

sulforaphane results in increased expression of ITGB2 mRNA

NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600

G

integrin subunit beta 7

increases expression

sulforaphane results in increased expression of ITGB7 mRNA

NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:133,347,960...133,364,876

G

inositol 1,4,5-trisphosphate receptor interacting protein

increases expression

sulforaphane results in increased expression of ITPRIP mRNA

NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408

G

IZUMO family member 4

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of IZUMO4 mRNA

NCBI chr 7:9,657,975...9,661,699
Ensembl chr 7:9,007,280...9,010,032

G

jade family PHD finger 3

decreases expression

sulforaphane results in decreased expression of JADE3 mRNA

NCBI chr X:4,222,369...4,424,164
Ensembl chr X:1,669,930...1,845,138

G

Janus kinase 2

multiple interactions

sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of JAK2 protein]

NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189

G

junctional cadherin complex regulator

increases expression

sulforaphane results in increased expression of JHY mRNA

NCBI chr 8:50,173,602...50,230,429
Ensembl chr 8:41,276,491...41,333,514

G

junctophilin 2

increases expression
decreases expression

sulforaphane results in increased expression of JPH2 mRNA
sulforaphane results in decreased expression of JPH2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:172,414,246...172,478,678
Ensembl chr 3:151,994,778...152,058,904

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases activity
increases expression

[sulforaphane promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; sulforaphane promotes the reaction [JUN protein binds to GSTP1 enhancer]
sulforaphane results in increased activity of JUN protein
sulforaphane results in increased expression of JUN protein

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases expression

sulforaphane results in decreased expression of JUND mRNA

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799

G

junction plakoglobin

decreases expression

sulforaphane results in decreased expression of JUP mRNA

NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,300,440...85,327,057

G

KN motif and ankyrin repeat domains 3

decreases expression

sulforaphane results in decreased expression of KANK3 mRNA

NCBI chr 7:15,296,538...15,309,838
Ensembl chr 7:14,594,422...14,607,675

G

lysine acetyltransferase 2B

increases expression

sulforaphane results in increased expression of KAT2B mRNA

NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064

G

potassium voltage-gated channel subfamily A member 3

decreases expression

sulforaphane results in decreased expression of KCNA3 mRNA

NCBI chr 2:197,320,324...197,322,277
Ensembl chr 2:194,632,196...194,650,138

G

potassium voltage-gated channel subfamily A regulatory beta subunit 2

increases expression

sulforaphane results in increased expression of KCNAB2 mRNA

NCBI chr 5:168,182,228...168,270,760
Ensembl chr 5:162,901,896...162,988,243

G

potassium voltage-gated channel subfamily D member 1

decreases expression

sulforaphane results in decreased expression of KCND1 mRNA

NCBI chr X:17,333,612...17,349,255
Ensembl chr X:14,662,357...14,677,233

G

potassium voltage-gated channel subfamily D member 2

increases expression

sulforaphane results in increased expression of KCND2 mRNA

NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:49,776,246...50,277,728

G

potassium voltage-gated channel subfamily E regulatory subunit 2

decreases expression

sulforaphane results in decreased expression of KCNE2 mRNA

NCBI chr11:45,003,468...45,015,942
Ensembl chr11:31,295,614...31,530,043

G

potassium voltage-gated channel modifier subfamily G member 2

increases expression

sulforaphane results in increased expression of KCNG2 mRNA

NCBI chr18:76,017,225...76,085,377
Ensembl chr18:73,743,074...73,808,723

G

potassium voltage-gated channel subfamily H member 2

increases expression

sulforaphane results in increased expression of KCNH2 mRNA

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008

G

potassium voltage-gated channel subfamily H member 3

multiple interactions

sulforaphane inhibits the reaction [fenamidone results in decreased expression of KCNH3 mRNA]

NCBI chr 7:132,244,492...132,262,725
Ensembl chr 7:130,366,011...130,383,855

G

potassium voltage-gated channel subfamily H member 5

decreases expression

sulforaphane results in decreased expression of KCNH5 mRNA

NCBI chr 6:99,350,947...99,643,856
Ensembl chr 6:93,624,529...93,908,107

G

potassium voltage-gated channel interacting protein 2

increases expression

sulforaphane results in increased expression of KCNIP2 mRNA

NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:244,641,150...244,664,874

G

potassium voltage-gated channel interacting protein 3

decreases expression

sulforaphane results in decreased expression of KCNIP3 mRNA

NCBI chr 3:135,130,331...135,196,031
Ensembl chr 3:114,677,030...114,743,556

G

potassium inwardly-rectifying channel, subfamily J, member 14

increases expression

sulforaphane results in increased expression of KCNJ14 mRNA

NCBI chr 1:105,429,607...105,437,258
Ensembl chr 1:96,293,435...96,495,459

G

potassium inwardly-rectifying channel, subfamily J, member 2

increases expression

sulforaphane results in increased expression of KCNJ2 mRNA

NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,060,821...96,071,445

G

potassium inwardly-rectifying channel, subfamily J, member 8

decreases expression

sulforaphane results in decreased expression of KCNJ8 mRNA

NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:175,508,912...175,515,603

G

potassium two pore domain channel subfamily K member 15

decreases expression

sulforaphane results in decreased expression of KCNK15 mRNA

NCBI chr 3:172,934,659...172,940,877
Ensembl chr 3:152,515,237...152,521,455

G

potassium two pore domain channel subfamily K member 7

increases expression

sulforaphane results in increased expression of KCNK7 mRNA

NCBI chr 1:212,419,555...212,422,173
Ensembl chr 1:202,990,198...202,992,872

G

potassium calcium-activated channel subfamily N member 4

increases expression

sulforaphane results in increased expression of KCNN4 mRNA

NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:79,959,322...79,974,340

G

potassium voltage-gated channel subfamily Q member 1

decreases expression

sulforaphane results in decreased expression of KCNQ1 mRNA

NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669

G

potassium voltage-gated channel subfamily Q member 3

decreases expression

sulforaphane results in decreased expression of KCNQ3 mRNA

NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:97,730,465...98,025,653

G

potassium channel tetramerization domain containing 12

decreases expression

sulforaphane results in decreased expression of KCTD12 mRNA

NCBI chr15:86,214,786...86,220,725
Ensembl chr15:79,801,191...79,806,282

G

Kelch-like ECH-associated protein 1

increases expression
multiple interactions
increases metabolic processing
increases response to substance
decreases response to substance
decreases expression

sulforaphane results in increased expression of KEAP1 protein
Iodoacetamide inhibits the reaction [sulforaphane results in increased metabolism of KEAP1 protein]; KEAP1 protein mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein]; sulforaphane inhibits the reaction [KEAP1 protein binds to CUL3 protein]; sulforaphane inhibits the reaction [sodium arsenite affects the localization of KEAP1 protein]; sulforaphane promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; sulforaphane promotes the reaction [NFE2L2 protein binds to KEAP1 protein]
KEAP1 protein results in increased susceptibility to sulforaphane
sulforaphane inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein]; sulforaphane inhibits the reaction [KEAP1 protein binds to CUL3 protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of KEAP1 mRNA]; sulforaphane promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]]
KEAP1 protein mutant form results in decreased susceptibility to sulforaphane
sulforaphane results in decreased expression of KEAP1 mRNA

PMID:15865434 PMID:18417180 PMID:19033392 PMID:21391649 PMID:22558124 More...

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862

G

KIAA0319 homolog

increases expression

sulforaphane results in increased expression of KIAA0319 mRNA

NCBI chr17:40,587,001...40,654,525
Ensembl chr17:40,165,084...40,225,653

G

KIAA0825 homolog

decreases expression

sulforaphane results in decreased expression of KIAA0825 mRNA

NCBI chr 2:8,606,257...9,167,308
Ensembl chr 2:6,874,539...7,434,521

G

kinesin family member 13A

decreases expression

sulforaphane results in decreased expression of KIF13A mRNA

NCBI chr17:17,972,227...18,154,763
Ensembl chr17:17,766,597...17,943,615

G

kinesin family member 14

increases expression

sulforaphane results in increased expression of KIF14 mRNA

NCBI chr13:50,478,646...50,542,256
Ensembl chr13:47,927,044...47,989,164

G

kinesin family member 18A

increases expression

sulforaphane results in increased expression of KIF18A mRNA

NCBI chr 3:116,219,007...116,279,378
Ensembl chr 3:95,764,388...95,824,582

G

KIT proto-oncogene receptor tyrosine kinase

decreases expression

sulforaphane results in decreased expression of KIT mRNA

NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652

G

KLF transcription factor 10

increases expression

sulforaphane results in increased expression of KLF10 mRNA

NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 4

multiple interactions

[Genistein co-treated with sulforaphane] results in decreased expression of KLF4 mRNA

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 7

decreases expression

sulforaphane results in decreased expression of KLF7 mRNA

NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:65,437,167...65,526,261

G

KLF transcription factor 9

multiple interactions
decreases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of KLF9 mRNA
sulforaphane results in decreased expression of KLF9 mRNA

PMID:25450479 PMID:30529165

NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:220,700,108...220,725,037

G

kelch-like family member 13

decreases expression

sulforaphane results in decreased expression of KLHL13 mRNA

NCBI chr X:118,747,298...118,912,279
Ensembl chr X:113,942,309...114,107,321

G

kelch-like family member 2

decreases expression

sulforaphane results in decreased expression of KLHL2 mRNA

NCBI chr16:29,627,171...29,739,782
Ensembl chr16:24,860,667...24,973,341

G

kelch-like family member 21

increases expression

sulforaphane results in increased expression of KLHL21 mRNA

NCBI chr 5:167,797,621...167,806,276
Ensembl chr 5:162,514,765...162,523,545

G

kelch-like family member 29

decreases expression

sulforaphane results in decreased expression of KLHL29 mRNA

PMID:30529165 PMID:31838189

NCBI chr 6:33,805,922...34,110,055
Ensembl chr 6:28,086,489...28,390,647

G

kallikrein related-peptidase 11

increases expression

sulforaphane results in increased expression of KLK11 mRNA

NCBI chr 1:103,365,290...103,369,830
Ensembl chr 1:94,228,741...94,233,281

G

kallikrein 1-related peptidase C10

multiple interactions
decreases expression

sulforaphane inhibits the reaction [AR protein binds to KLK3 enhancer]
sulforaphane results in decreased expression of KLK3 mRNA

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:94,402,993...94,407,052

G

lysine methyltransferase 5C

decreases expression

sulforaphane results in decreased expression of KMT5C mRNA

NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:69,099,539...69,107,145

G

kininogen 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of KNG1 mRNA

NCBI chr11:91,317,354...91,340,148
Ensembl chr11:77,812,752...77,835,555

G

kinetochore-localized astrin/SPAG5 binding protein

increases expression

sulforaphane results in increased expression of KNSTRN mRNA

NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:105,800,954...105,820,715

G

lysine-rich coiled-coil 1

increases expression

sulforaphane results in increased expression of KRCC1 mRNA

NCBI chr 4:104,819,958...104,832,987
Ensembl chr 4:103,261,536...103,277,156

G

KRI1 homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of KRI1 mRNA

NCBI chr 8:28,093,175...28,107,576
Ensembl chr 8:19,817,017...19,831,392

G

KRR1, small subunit processome component homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of KRR1 mRNA

NCBI chr 7:49,361,794...49,374,222
Ensembl chr 7:47,475,557...47,486,985

G

keratin 15

increases expression

sulforaphane results in increased expression of KRT15 mRNA

NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,066,802...85,171,799

G

keratin 17

decreases expression

sulforaphane results in decreased expression of KRT17 mRNA

NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,178,675...85,183,392

G

keratin 4

decreases expression

sulforaphane results in decreased expression of KRT4 mRNA

NCBI chr 7:134,924,753...134,931,050
Ensembl chr 7:133,046,515...133,052,019

G

keratin 7

decreases expression

sulforaphane results in decreased expression of KRT7 mRNA

NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:132,528,895...132,545,052

G

keratin 8

decreases expression
increases methylation

sulforaphane results in decreased expression of KRT8 mRNA
sulforaphane results in increased methylation of KRT8 gene

NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:133,124,203...133,131,728

G

keratin 80

decreases expression

sulforaphane results in decreased expression of KRT80 mRNA

NCBI chr 7:134,341,951...134,363,872
Ensembl chr 7:132,463,218...132,485,508

G

keratin 86

decreases expression

sulforaphane results in decreased expression of KRT86 mRNA

NCBI chr 7:134,470,224...134,476,873
Ensembl chr 7:132,591,545...132,598,021

G

keratin associated protein 17-1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of KRTAP17-1 mRNA

NCBI chr10:84,923,920...84,924,634
Ensembl chr10:84,923,922...84,924,634

G

kynureninase

decreases expression

sulforaphane results in decreased expression of KYNU mRNA

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:27,778,772...27,929,488

G

trans-L-3-hydroxyproline dehydratase

increases expression

sulforaphane results in increased expression of L3HYPDH mRNA

NCBI chr 6:96,372,243...96,383,039
Ensembl chr 6:90,636,310...90,647,106

G

laminin subunit alpha 1

increases expression

sulforaphane results in increased expression of LAMA1 mRNA

NCBI chr 9:115,139,548...115,263,620
Ensembl chr 9:107,692,770...107,817,478

G

laminin subunit alpha 3

decreases expression

sulforaphane results in decreased expression of LAMA3 mRNA

NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,523,133...3,751,353

G

laminin subunit beta 3

increases expression

sulforaphane results in increased expression of LAMB3 mRNA

NCBI chr13:107,362,514...107,404,081
Ensembl chr13:104,833,873...104,875,405

G

lysosomal-associated membrane protein 2

increases expression
multiple interactions

sulforaphane results in increased expression of LAMP2 mRNA alternative form; sulforaphane results in increased expression of LAMP2 protein alternative form
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of LAMP2 protein alternative form]

NCBI chr X:122,038,734...122,087,745
Ensembl chr X:117,057,606...117,260,522

G

lysosomal-associated membrane protein family, member 5

decreases expression

sulforaphane results in decreased expression of LAMP5 mRNA

NCBI chr 3:143,825,197...143,837,699
Ensembl chr 3:123,372,462...123,384,952

G

LanC like family member 3

increases expression

sulforaphane results in increased expression of LANCL3 mRNA

NCBI chr X:16,150,991...16,282,425
Ensembl chr X:13,480,311...13,609,678

G

ligand dependent nuclear receptor corepressor-like

decreases expression

sulforaphane results in decreased expression of LCORL mRNA

NCBI chr14:69,482,919...69,620,269
Ensembl chr14:65,271,135...65,404,174

G

LIM domain binding 3

increases expression

sulforaphane results in increased expression of LDB3 mRNA

NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,855,927...9,918,532

G

lactate dehydrogenase D

decreases expression

sulforaphane results in decreased expression of LDHD mRNA

NCBI chr19:56,492,827...56,497,695
Ensembl chr19:39,573,621...39,595,575

G

leptin receptor

decreases expression
affects response to substance
multiple interactions

sulforaphane results in decreased expression of LEPR mRNA
LEPR protein affects the susceptibility to sulforaphane
[LEPR protein affects the susceptibility to sulforaphane] which affects the expression of CNR2 protein

PMID:29143802 PMID:30529165

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908

G

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

decreases expression

sulforaphane results in decreased expression of LFNG mRNA

NCBI chr12:19,144,474...19,152,951
Ensembl chr12:14,018,333...14,039,008

G

galectin 1

affects binding
decreases expression

LGALS1 protein binds to sulforaphane
sulforaphane results in decreased expression of LGALS1 mRNA

PMID:21838287 PMID:31838189

NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345

G

galectin 12

increases expression

sulforaphane results in increased expression of LGALS12 mRNA

NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759

G

leucine-rich repeat LGI family, member 3

decreases expression

sulforaphane results in decreased expression of LGI3 mRNA

NCBI chr15:52,015,317...52,022,445
Ensembl chr15:45,605,611...45,612,739

G

lengsin, lens protein with glutamine synthetase domain

decreases expression

sulforaphane results in decreased expression of LGSN mRNA

NCBI chr 9:40,912,398...40,943,955
Ensembl chr 9:33,420,484...33,447,907

G

LIM homeobox 2

decreases expression

sulforaphane results in decreased expression of LHX2 mRNA

NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:22,126,007...22,143,908

G

leukocyte immunoglobulin like receptor B4

decreases expression

sulforaphane results in decreased expression of LILRB4 mRNA

NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660

G

LIM domain and actin binding 1

multiple interactions
decreases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of LIMA1 mRNA]
sulforaphane results in decreased expression of LIMA1 mRNA

PMID:27029645 PMID:31838189

NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:130,901,717...131,001,473

G

LIM zinc finger domain containing 2

decreases expression

sulforaphane results in decreased expression of LIMS2 mRNA

NCBI chr18:23,828,164...23,866,363
Ensembl chr18:23,553,937...23,592,137

G

lipopolysaccharide-induced TNF factor

increases expression

sulforaphane results in increased expression of LITAF mRNA

NCBI chr10:5,163,258...5,199,930
Ensembl chr10:4,625,552...4,692,763

G

lipase maturation factor 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of LMF2 mRNA

NCBI chr 7:122,297,971...122,302,423
Ensembl chr 7:120,418,345...120,422,823

G

LIM domain only 1

decreases expression

sulforaphane results in decreased expression of LMO1 mRNA

NCBI chr 1:172,567,156...172,603,282
Ensembl chr 1:163,132,339...163,168,522

G

LIM domain only 4

decreases expression

sulforaphane results in decreased expression of LMO4 mRNA

NCBI chr 2:235,924,574...235,941,609
Ensembl chr 2:233,264,182...233,280,880

G

ligand of numb-protein X 1

increases expression

sulforaphane results in increased expression of LNX1 mRNA

NCBI chr14:33,868,517...33,971,217
Ensembl chr14:33,514,436...33,617,086

G

U5 spliceosomal RNA

decreases expression

sulforaphane results in decreased expression of RNU5E-4P mRNA

NCBI chr13:83,931,881...83,931,996
Ensembl chr13:83,931,881...83,931,996

G

lysyl oxidase

decreases expression

sulforaphane results in decreased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477

G

lysophosphatidylcholine acyltransferase 2

increases expression

sulforaphane results in increased expression of LPCAT2 mRNA

NCBI chr19:30,261,369...30,325,715
Ensembl chr19:14,089,686...14,152,829

G

lipin 2

decreases expression

sulforaphane results in decreased expression of LPIN2 mRNA

NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:111,083,745...111,158,193

G

lipoprotein lipase

increases expression

sulforaphane results in increased expression of LPL mRNA

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249

G

leucine-rich alpha-2-glycoprotein 1

increases expression

sulforaphane results in increased expression of LRG1 mRNA

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:947,516...949,813

G

leucine-rich repeats and immunoglobulin-like domains 1

increases expression

sulforaphane results in increased expression of LRIG1 mRNA

NCBI chr 4:128,687,723...128,788,219
Ensembl chr 4:127,130,898...127,231,513

G

LDL receptor related protein 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of LRP1 mRNA

NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910

G

LDL receptor related protein 10

increases expression

sulforaphane results in increased expression of LRP10 mRNA

NCBI chr15:31,891,358...31,897,530
Ensembl chr15:27,920,259...27,927,505

G

LDL receptor related protein 12

increases expression

sulforaphane results in increased expression of LRP12 mRNA

NCBI chr 7:72,825,979...72,897,308
Ensembl chr 7:70,941,068...71,012,441

G

LDL receptor related protein 2

decreases expression

sulforaphane results in decreased expression of LRP2 mRNA

NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:54,189,308...54,346,708

G

LDL receptor related protein 8

increases expression

sulforaphane results in increased expression of LRP8 mRNA

NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:122,563,453...122,631,352

G

leucine rich repeat containing 14B

decreases expression

sulforaphane results in decreased expression of LRRC14B mRNA

NCBI chr 1:28,921,475...28,925,646
Ensembl chr 1:28,921,416...28,925,378

G

leucine rich repeat containing 20

decreases expression

sulforaphane results in decreased expression of LRRC20 mRNA

NCBI chr20:29,422,858...29,528,372
Ensembl chr20:29,422,925...29,528,369

G

leucine rich repeat containing 34

increases expression

sulforaphane results in increased expression of LRRC34 mRNA

NCBI chr 2:114,680,787...114,702,961
Ensembl chr 2:112,754,578...112,774,459

G

leucine rich repeat containing 3B

increases expression

sulforaphane results in increased expression of LRRC3B mRNA

NCBI chr15:12,404,309...12,481,618
Ensembl chr15:9,969,983...10,051,066

G

leucine rich repeat containing 45

decreases expression

sulforaphane results in decreased expression of LRRC45 mRNA

NCBI chr10:105,994,468...106,002,425
Ensembl chr10:105,993,087...106,002,424

G

leucine rich repeat containing 51

increases expression

sulforaphane results in increased expression of LRRC51 mRNA

NCBI chr 1:165,690,617...165,709,837
Ensembl chr 1:156,278,618...156,297,773

G

leucine rich repeat containing 73

decreases expression

sulforaphane results in decreased expression of LRRC73 mRNA

NCBI chr 9:14,726,157...14,730,144
Ensembl chr 9:14,726,158...14,729,158

G

leucine-rich repeat kinase 2

decreases expression

sulforaphane results in decreased expression of LRRK2 mRNA

NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703

G

lymphocyte-specific protein 1

increases expression

sulforaphane results in increased expression of LSP1 mRNA

NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:197,614,687...197,648,416

G

lanosterol synthase

decreases expression

sulforaphane results in decreased expression of LSS mRNA

NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762

G

leukocyte specific transcript 1

increases expression

sulforaphane results in increased expression of LST1 mRNA

NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,634,749...3,637,997

G

leukotriene A4 hydrolase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of LTA4H mRNA

NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:27,969,789...28,001,600

G

lactotransferrin

increases expression

sulforaphane results in increased expression of LTF mRNA

NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795

G

lumican

decreases expression

sulforaphane results in decreased expression of LUM mRNA

NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:32,358,614...32,365,793

G

latexin

decreases expression

sulforaphane results in decreased expression of LXN mRNA

NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:151,727,102...151,733,460

G

Ly6/neurotoxin 1

increases expression

sulforaphane results in increased expression of LYNX1 mRNA

NCBI chr 7:108,521,783...108,527,012
Ensembl chr 7:106,632,797...106,638,023

G

Ly6/Plaur domain containing 6

decreases expression

sulforaphane results in decreased expression of LYPD6 mRNA

NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:34,496,485...34,630,308

G

LysM domain containing 2

increases expression

sulforaphane results in increased expression of LYSMD2 mRNA

NCBI chr 8:85,259,443...85,274,876
Ensembl chr 8:76,379,219...76,394,654

G

meiosis 1 associated protein

decreases expression

sulforaphane results in decreased expression of M1AP mRNA

NCBI chr 4:115,445,910...115,536,745
Ensembl chr 4:115,455,397...115,536,487

G

MET transcriptional regulator MACC1

decreases expression

sulforaphane results in decreased expression of MACC1 mRNA

NCBI chr 6:146,495,544...146,574,254
Ensembl chr 6:140,352,755...140,430,255

G

mono-ADP ribosylhydrolase 1

increases expression

sulforaphane results in increased expression of MACROD1 mRNA

NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:204,246,166...204,389,716

G

MAF bZIP transcription factor G

increases expression
affects expression

sulforaphane results in increased expression of MAFG mRNA
sulforaphane affects the expression of MAFG mRNA

PMID:31838189 PMID:35724838

NCBI chr10:106,401,633...106,410,159
Ensembl chr10:105,903,237...105,912,026

G

MAGE family member B2

decreases expression

sulforaphane results in decreased expression of MAGEB2 mRNA

NCBI chr X:54,778,318...54,784,040
Ensembl chr X:50,827,563...50,833,151

G

membrane associated guanylate kinase, WW and PDZ domain containing 3

decreases expression

sulforaphane results in decreased expression of MAGI3 mRNA

NCBI chr 2:194,206,587...194,405,468
Ensembl chr 2:191,518,506...191,716,735

G

MAM domain containing 2

decreases expression

sulforaphane results in decreased expression of MAMDC2 mRNA

NCBI chr 1:230,290,482...230,443,014
Ensembl chr 1:220,863,976...221,016,354

G

MAM domain containing 4

decreases expression

sulforaphane results in decreased expression of MAMDC4 mRNA

NCBI chr 3:28,780,523...28,789,139
Ensembl chr 3:8,382,387...8,391,003

G

microtubule-associated protein 1B

decreases expression

sulforaphane results in decreased expression of MAP1B mRNA

NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:30,817,261...30,910,317

G

microtubule-associated protein 1 light chain 3 beta

increases expression
multiple interactions

sulforaphane results in increased expression of MAP1LC3B mRNA
sulforaphane inhibits the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]

PMID:32111854 PMID:37567421

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

microtubule-associated protein 2

increases expression

sulforaphane results in increased expression of MAP2 mRNA

NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase 4

increases expression

sulforaphane results in increased expression of MAP2K4 mRNA

NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993

G

mitogen-activated protein kinase kinase 6

decreases expression

sulforaphane results in decreased expression of MAP2K6 mRNA

PMID:26833863 PMID:31838189

NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,373,204...95,488,293

G

mitogen activated protein kinase kinase kinase 12

decreases expression

sulforaphane results in decreased expression of MAP3K12 mRNA

NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:133,630,835...133,640,789

G

mitogen-activated protein kinase kinase kinase 6

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MAP3K6 mRNA
sulforaphane results in decreased expression of MAP3K6 mRNA

NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:145,440,346...145,452,212

G

mitogen-activated protein kinase kinase kinase 8

decreases expression

sulforaphane results in decreased expression of MAP3K8 mRNA

PMID:30529165 PMID:31838189

NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK1 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK1 protein]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK1 protein]; sulforaphane results in increased phosphorylation of and results in increased activity of MAPK1 protein
sulforaphane inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK1 protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased phosphorylation of MAPK1 protein]
sulforaphane results in increased phosphorylation of MAPK1 protein

PMID:15896333 PMID:22005276 PMID:23518299 PMID:25933243 PMID:32387680 More...

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK3 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK3 protein]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK3 protein]; sulforaphane results in increased phosphorylation of and results in increased activity of MAPK3 protein
sulforaphane inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK3 protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased phosphorylation of MAPK3 protein]
sulforaphane results in increased phosphorylation of MAPK3 protein

PMID:15896333 PMID:22005276 PMID:23518299 PMID:25933243 PMID:32387680 More...

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 4

decreases expression

sulforaphane results in decreased expression of MAPK4 mRNA

NCBI chr18:69,788,058...69,937,524
Ensembl chr18:67,512,807...67,661,842

G

mitogen-activated protein kinase 8

increases activity
multiple interactions

sulforaphane results in increased activity of MAPK8 protein
sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK8 protein]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK8 protein]
[sulforaphane co-treated with Acetaminophen] results in increased phosphorylation of MAPK8 protein

PMID:16201852 PMID:25933243 PMID:32387680 PMID:37598316

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions

sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK9 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK9 protein]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased phosphorylation of MAPK9 protein]

PMID:25933243 PMID:32387680

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178

G

MAPK activated protein kinase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MAPKAPK2 mRNA

NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457

G

microtubule-associated protein, RP/EB family, member 3

increases expression

sulforaphane results in increased expression of MAPRE3 mRNA

NCBI chr 6:31,233,736...31,278,626
Ensembl chr 6:25,513,800...25,558,881

G

myristoylated alanine rich protein kinase C substrate

decreases expression

sulforaphane results in decreased expression of MARCKS mRNA

NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012

G

MARCO like

decreases expression

sulforaphane results in decreased expression of MARCOL mRNA

NCBI chr18:36,699,606...36,706,063

G

microtubule associated tyrosine carboxypeptidase 1

decreases expression

sulforaphane results in decreased expression of MATCAP1 mRNA

NCBI chr19:50,067,978...50,076,715
Ensembl chr19:33,158,056...33,166,445

G

myoglobin

decreases expression

sulforaphane results in decreased expression of MB mRNA

NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383

G

methyl-CpG binding domain protein 2

multiple interactions

sulforaphane inhibits the reaction [Estradiol promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in increased activity of MBD2 protein]; sulforaphane inhibits the reaction [Estradiol results in increased expression of MBD2 mRNA]; sulforaphane inhibits the reaction [Genistein promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Genistein results in increased activity of MBD2 protein]

NCBI chr18:66,449,196...66,516,112
Ensembl chr18:64,174,002...64,240,794

G

methyl-CpG binding domain protein 3

increases expression

sulforaphane results in increased expression of MBD3 mRNA

NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,313,098...9,320,165

G

MAP3K12 binding inhibitory protein 1

decreases expression

sulforaphane results in decreased expression of MBIP mRNA

NCBI chr 6:79,543,223...79,560,476
Ensembl chr 6:73,808,133...73,825,374

G

methylcrotonyl-CoA carboxylase subunit 1

decreases expression

sulforaphane results in decreased expression of MCCC1 mRNA

NCBI chr 2:120,727,313...120,779,334
Ensembl chr 2:118,799,150...118,851,222

G

methylmalonyl CoA epimerase

decreases expression

sulforaphane results in decreased expression of MCEE mRNA

NCBI chr 1:127,376,311...127,399,551
Ensembl chr 1:117,964,576...117,988,484

G

mucolipin TRP cation channel 2

decreases expression

sulforaphane results in decreased expression of MCOLN2 mRNA

NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702

G

mucolipin TRP cation channel 3

decreases expression

sulforaphane results in decreased expression of MCOLN3 mRNA

NCBI chr 2:235,008,716...235,042,885
Ensembl chr 2:234,966,010...235,043,047

G

MAPK regulated co-repressor interacting protein 2

increases expression

sulforaphane results in increased expression of MCRIP2 mRNA

NCBI chr10:15,388,325...15,393,302
Ensembl chr10:14,883,813...14,894,021

G

multiple C2 and transmembrane domain containing 1

increases expression

sulforaphane results in increased expression of MCTP1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:6,065,808...6,761,833

G

multiple C2 and transmembrane domain containing 2

increases expression
decreases expression

sulforaphane results in increased expression of MCTP2 mRNA
sulforaphane results in decreased expression of MCTP2 mRNA

PMID:26833863 PMID:31838189

NCBI chr 1:135,179,845...135,412,798
Ensembl chr 1:125,771,233...126,002,928

G

malate dehydrogenase 1

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of MDH1 mRNA
sulforaphane results in increased expression of MDH1 mRNA

PMID:25450479 PMID:30529165

NCBI chr14:99,831,934...99,847,227
Ensembl chr14:95,630,306...95,645,925

G

malic enzyme 1

increases expression

sulforaphane results in increased expression of ME1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304

G

malic enzyme 3

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ME3 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ME3 mRNA

PMID:25450479 PMID:30529165

NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:143,534,139...143,733,132

G

multiple EGF-like-domains 9

increases expression

sulforaphane results in increased expression of MEGF9 mRNA

NCBI chr 5:89,008,679...89,120,731
Ensembl chr 5:83,993,565...84,105,622

G

mesenchyme homeobox 1

decreases expression

sulforaphane results in decreased expression of MEOX1 mRNA

NCBI chr10:87,318,668...87,338,169
Ensembl chr10:86,818,478...86,837,660

G

MER proto-oncogene, tyrosine kinase

decreases expression

sulforaphane results in decreased expression of MERTK mRNA

NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:115,939,351...116,046,554

G

methionyl aminopeptidase type 1D (mitochondrial)

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of METAP1D mRNA

NCBI chr 3:56,279,471...56,354,518
Ensembl chr 3:56,279,493...56,351,981

G

microfibril associated protein 2

decreases expression

sulforaphane results in decreased expression of MFAP2 mRNA

NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:153,314,711...153,320,259

G

microfibril associated protein 4

decreases expression

sulforaphane results in decreased expression of MFAP4 mRNA

NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,167,217...46,170,155

G

mitofusin 2

multiple interactions

sulforaphane affects the reaction [Carbon Monoxide results in decreased expression of MFN2 protein]; sulforaphane inhibits the reaction [Carbon Monoxide results in decreased expression of MFN2 mRNA]

NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342

G

maltase-glucoamylase

increases expression

sulforaphane results in increased expression of MGAM mRNA

NCBI chr 4:70,408,263...70,568,752
Ensembl chr 4:69,446,150...69,692,715

G

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

increases expression

sulforaphane results in increased expression of MGAT5 mRNA

NCBI chr13:41,228,327...41,516,462
Ensembl chr13:38,676,119...38,959,513

G

monoglyceride lipase

decreases expression

sulforaphane results in decreased expression of MGLL mRNA

NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

sulforaphane results in increased expression of and results in increased activity of MGMT protein

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756

G

MIA SH3 domain ER export factor 2

increases expression

sulforaphane results in increased expression of MIA2 mRNA

NCBI chr 6:82,522,398...82,620,136
Ensembl chr 6:76,787,508...76,885,211

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

decreases expression

sulforaphane results in decreased expression of MICAL2 mRNA

NCBI chr 1:175,780,441...175,965,157
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719

G

MINDY lysine 48 deubiquitinase 1

decreases expression

sulforaphane results in decreased expression of MINDY1 mRNA

NCBI chr 2:185,550,026...185,561,987
Ensembl chr 2:182,860,472...182,873,015

G

microRNA 142

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MIR142 mRNA

NCBI chr10:73,055,104...73,055,190
Ensembl chr10:72,557,857...72,557,967

G

microRNA 34a

multiple interactions

sulforaphane inhibits the reaction [ochratoxin A results in increased expression of MIR34A mRNA]

NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103

G

microRNA 382

multiple interactions

sulforaphane inhibits the reaction [ochratoxin A results in increased expression of MIR382 mRNA]

NCBI chr 6:134,569,944...134,570,023

G

modulator of VRAC current 1

decreases expression

sulforaphane results in decreased expression of MLC1 mRNA

NCBI chr 7:121,926,356...121,949,484
Ensembl chr 7:120,046,705...120,067,049

G

myeloid leukemia factor 1

increases expression

sulforaphane results in increased expression of MLF1 mRNA

NCBI chr 2:153,958,060...153,991,705
Ensembl chr 2:151,648,511...151,681,652

G

muscular LMNA-interacting protein

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MLIP mRNA

NCBI chr 8:86,815,491...87,085,117
Ensembl chr 8:77,935,079...78,204,254

G

MLX interacting protein-like

increases expression

sulforaphane results in increased expression of MLXIPL mRNA

NCBI chr12:27,178,158...27,213,675
Ensembl chr12:21,543,576...21,577,112

G

membrane metallo-endopeptidase

decreases expression

sulforaphane results in decreased expression of MME mRNA

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 2

increases expression

sulforaphane results in increased expression of MMP2 mRNA

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 28

decreases expression

sulforaphane results in decreased expression of MMP28 mRNA

NCBI chr10:68,738,651...68,762,377
Ensembl chr10:68,241,138...68,264,866

G

multimerin 2

decreases expression

sulforaphane results in decreased expression of MMRN2 mRNA

NCBI chr16:9,712,181...9,733,653
Ensembl chr16:9,705,892...9,727,405

G

MNAT1 component of CDK activating kinase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of MNAT1 mRNA

NCBI chr 6:97,550,566...97,706,598
Ensembl chr 6:91,814,749...91,970,744

G

myeloid cell nuclear differentiation antigen

increases expression

sulforaphane results in increased expression of MNDA mRNA

NCBI chr13:88,550,224...88,567,892
Ensembl chr13:86,017,892...86,034,201

G

meiosis-specific nuclear structural 1

decreases expression

sulforaphane results in decreased expression of MNS1 mRNA

NCBI chr 8:82,029,587...82,050,276
Ensembl chr 8:73,148,877...73,176,925

G

MOB kinase activator 3B

decreases expression

sulforaphane results in decreased expression of MOB3B mRNA

NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:49,545,815...49,737,934

G

MOB family member 4, phocein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MOB4 mRNA

NCBI chr 9:64,111,170...64,135,740
Ensembl chr 9:56,617,368...56,641,329

G

modulator of smoothened

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MOSMO mRNA

NCBI chr 1:184,648,985...184,719,820
Ensembl chr 1:175,217,545...175,288,334

G

monooxygenase, DBH-like 1

decreases expression

sulforaphane results in decreased expression of MOXD1 mRNA

NCBI chr 1:22,894,543...22,984,599
Ensembl chr 1:21,075,122...21,161,779

G

macrophage expressed 1

decreases expression

sulforaphane results in decreased expression of MPEG1 mRNA

NCBI chr 1:218,876,848...218,881,364
Ensembl chr 1:209,452,133...209,458,855

G

M phase phosphoprotein 6

increases expression

sulforaphane results in increased expression of MPHOSPH6 mRNA

NCBI chr19:62,768,909...62,778,874
Ensembl chr19:45,860,154...45,870,170

G

MPN domain containing

decreases expression

sulforaphane results in decreased expression of MPND mRNA

NCBI chr 9:926,714...933,620
Ensembl chr 9:840,143...846,439

G

MAGUK p55 scaffold protein 2

decreases expression

sulforaphane results in decreased expression of MPP2 mRNA

NCBI chr10:87,511,638...87,544,710
Ensembl chr10:87,011,434...87,043,896

G

MAGUK p55 scaffold protein 7

decreases expression

sulforaphane results in decreased expression of MPP7 mRNA

NCBI chr17:60,135,096...60,401,814
Ensembl chr17:55,442,696...55,706,748

G

myelin protein zero-like 1

decreases expression

sulforaphane results in decreased expression of MPZL1 mRNA

NCBI chr13:80,385,454...80,422,315
Ensembl chr13:77,852,467...77,896,616

G

myelin protein zero-like 2

decreases expression

sulforaphane results in decreased expression of MPZL2 mRNA

NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:45,348,285...45,359,298

G

myelin protein zero-like 3

increases expression

sulforaphane results in increased expression of MPZL3 mRNA

NCBI chr 8:54,257,235...54,277,422
Ensembl chr 8:45,349,054...45,380,662

G

melanocortin 2 receptor accessory protein

increases expression

sulforaphane results in increased expression of MRAP mRNA

NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024

G

maestro

increases expression

sulforaphane results in increased expression of MRO mRNA

NCBI chr18:69,723,764...69,742,815
Ensembl chr18:67,450,595...67,467,044

G

mitochondrial ribosomal protein L13

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MRPL13 mRNA

NCBI chr 7:88,841,265...88,862,821
Ensembl chr 7:86,951,541...86,973,577

G

mitochondrial ribosomal protein L28

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MRPL28 mRNA

NCBI chr10:15,653,006...15,656,062
Ensembl chr10:15,148,681...15,151,581

G

mitochondrial ribosomal protein L53

increases expression

sulforaphane results in increased expression of MRPL53 mRNA

NCBI chr 4:117,173,043...117,173,933

G

mitochondrial ribosomal protein S24

decreases expression

sulforaphane results in decreased expression of MRPS24 mRNA

NCBI chr14:84,798,649...84,802,777
Ensembl chr14:80,584,673...80,588,871

G

membrane spanning 4-domains A6A

decreases expression

sulforaphane results in decreased expression of MS4A6A mRNA

NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:208,401,466...208,414,758

G

musculin

increases expression

sulforaphane results in increased expression of MSC mRNA

NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:4,547,405...4,553,203

G

methionine sulfoxide reductase B1

increases expression

sulforaphane results in increased expression of MSRB1 mRNA

NCBI chr10:14,269,414...14,275,140
Ensembl chr10:13,764,883...13,770,609

G

macrophage stimulating 1

increases expression

sulforaphane results in increased expression of MST1 mRNA

NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:108,768,839...108,773,416

G

mitochondrially encoded cytochrome c oxidase I

multiple interactions

[sulforaphane co-treated with Oxygen] results in increased expression of COX1 protein; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Oxygen] results in increased expression of COX1 protein]

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1

increases expression

sulforaphane results in increased expression of ND1 protein

NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694

G

metallothionein 1, pseudogene 3

decreases expression

sulforaphane results in decreased expression of MT1E mRNA

NCBI chr17:79,695,812...79,696,200
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2

increases expression

sulforaphane results in increased expression of MT2 mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

metallothionein 3

increases expression

sulforaphane results in increased expression of MT3 mRNA

NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,848,755...10,850,158

G

microtubule crosslinking factor 1

decreases expression

sulforaphane results in decreased expression of SOGA2 mRNA

NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:106,321,098...106,442,203

G

mitochondrial fission process 1

increases expression

sulforaphane results in increased expression of MTFP1 mRNA

NCBI chr14:83,192,013...83,195,853
Ensembl chr14:78,968,442...78,972,274

G

myotubularin related protein 10

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MTMR10 mRNA
sulforaphane results in decreased expression of MTMR10 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:127,271,139...127,322,621
Ensembl chr 1:117,859,267...117,910,849

G

myotubularin related protein 11

decreases expression

sulforaphane results in decreased expression of MTMR11 mRNA

NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:183,723,530...183,732,148

G

5-methyltetrahydrofolate-homocysteine methyltransferase

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MTR mRNA

NCBI chr17:62,911,705...62,996,544
Ensembl chr17:58,220,071...58,304,822

G

Mtr4 exosome RNA helicase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SKIV2L2 mRNA

NCBI chr 2:46,233,528...46,293,827
Ensembl chr 2:44,461,444...44,560,627

G

microtubule associated scaffold protein 2

increases expression

sulforaphane results in increased expression of MTUS2 mRNA

NCBI chr12:11,742,713...12,115,798
Ensembl chr12:6,706,532...7,078,331

G

mucin 1, cell surface associated

decreases expression

sulforaphane results in decreased expression of MUC1 mRNA

NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:174,635,995...174,640,733

G

mucin 19, oligomeric

decreases expression

sulforaphane results in decreased expression of MUC19 mRNA

NCBI chr 7:124,897,424...125,018,582
Ensembl chr 7:123,017,896...123,139,053

G

mucin 3A, cell surface associated

decreases expression

sulforaphane results in decreased expression of MUC3A mRNA

NCBI chr12:25,082,728...25,091,494
Ensembl chr12:19,446,094...19,460,522

G

mucin 5AC, oligomeric mucus/gel-forming

multiple interactions
increases expression

NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Oxygen results in increased secretion of MUC5AC protein]]; sulforaphane affects the reaction [NFE2L2 protein affects the secretion of MUC5AC protein]; sulforaphane inhibits the reaction [Oxygen results in increased secretion of MUC5AC protein]
sulforaphane results in increased expression of MUC5AC mRNA

NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:196,864,336...196,896,475

G

mucin 5B, oligomeric mucus/gel-forming

increases expression

sulforaphane results in increased expression of MUC5B mRNA

NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:196,916,825...196,949,250

G

mevalonate kinase

decreases expression

sulforaphane results in decreased expression of MVK mRNA

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882

G

major vault protein

decreases expression

sulforaphane results in decreased expression of MVP mRNA

NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:181,594,734...181,622,380

G

max dimerization protein 1

increases expression

sulforaphane results in increased expression of MXD1 mRNA

NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:119,097,353...119,117,751

G

Max dimerization protein 4

decreases expression

sulforaphane results in decreased expression of MXD4 mRNA

NCBI chr14:80,786,768...80,800,790
Ensembl chr14:76,561,774...76,576,221

G

MYB proto-oncogene, transcription factor

increases expression
decreases expression

sulforaphane results in increased expression of MYB mRNA
sulforaphane results in decreased expression of MYB mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:15,939,761...15,973,057

G

MYB proto-oncogene like 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of MYBL2 mRNA

NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:151,705,288...151,733,708

G

myosin binding protein C3

increases expression

sulforaphane results in increased expression of MYBPC3 mRNA

NCBI chr 3:97,550,974...97,569,216
Ensembl chr 3:77,095,252...77,113,405

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions

sulforaphane inhibits the reaction [ochratoxin A results in increased expression of MYC mRNA]

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630

G

MYD88, innate immune signal transduction adaptor

multiple interactions

sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of MYD88 protein]

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415

G

myosin heavy chain 6

increases expression

sulforaphane results in increased expression of MYH6 mRNA

NCBI chr15:32,388,102...32,413,663
Ensembl chr15:28,417,616...28,441,720

G

myosin light chain 3

increases expression

sulforaphane results in increased expression of MYL3 mRNA

NCBI chr 8:119,617,077...119,623,215
Ensembl chr 8:110,738,661...110,744,816

G

myosin light chain kinase

decreases expression

sulforaphane results in decreased expression of MYLK mRNA

NCBI chr11:79,288,243...79,535,450
Ensembl chr11:65,783,008...66,030,261

G

myosin light chain kinase 3

multiple interactions
increases expression
decreases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MYLK3 mRNA
sulforaphane results in increased expression of MYLK3 mRNA
sulforaphane results in decreased expression of MYLK3 mRNA

PMID:30529165 PMID:31838189

NCBI chr19:37,858,298...37,916,805
Ensembl chr19:21,691,929...21,742,954

G

myosin Ib

decreases expression

sulforaphane results in decreased expression of MYO1B mRNA

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:49,690,086...49,850,798

G

myosin ID

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of MYO1D mRNA

NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,489,154...65,766,349

G

myosin IG

decreases expression

sulforaphane results in decreased expression of MYO1G mRNA

NCBI chr14:85,600,619...85,615,760
Ensembl chr14:81,386,701...81,401,843

G

myocardin

decreases expression

sulforaphane results in decreased expression of MYOCD mRNA

NCBI chr10:50,332,356...50,426,819
Ensembl chr10:49,836,641...49,927,627

G

myomesin 1

increases expression

sulforaphane results in increased expression of MYOM1 mRNA

NCBI chr 9:118,362,547...118,485,954
Ensembl chr 9:110,915,943...111,039,344

G

myomesin 2

increases expression

sulforaphane results in increased expression of MYOM2 mRNA

NCBI chr16:81,222,467...81,295,025
Ensembl chr16:74,520,157...74,592,772

G

myozenin 2

multiple interactions
increases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MYOZ2 mRNA
sulforaphane results in increased expression of MYOZ2 mRNA

NCBI chr 2:213,826,052...213,852,778
Ensembl chr 2:211,141,463...211,168,221

G

myopalladin

decreases expression

sulforaphane results in decreased expression of MYPN mRNA

NCBI chr20:25,435,554...25,521,149
Ensembl chr20:25,436,843...25,522,443

G

myosin VIIA and Rab interacting protein

decreases expression

sulforaphane results in decreased expression of MYRIP mRNA

NCBI chr 8:128,895,371...129,062,420
Ensembl chr 8:120,017,524...120,183,833

G

myb-like, SWIRM and MPN domains 1

decreases expression

sulforaphane results in decreased expression of MYSM1 mRNA

NCBI chr 5:114,877,112...114,981,463
Ensembl chr 5:109,776,286...109,819,967

G

myelin transcription factor 1-like

decreases expression

sulforaphane results in decreased expression of MYT1L mRNA

NCBI chr 6:51,892,858...52,291,830
Ensembl chr 6:46,428,150...46,561,671

G

N(alpha)-acetyltransferase 30, NatC catalytic subunit

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of NAA30 mRNA

NCBI chr15:24,935,060...24,954,435
Ensembl chr15:22,455,662...22,474,789

G

napsin A aspartic peptidase

decreases expression

sulforaphane results in decreased expression of NAPSA mRNA

NCBI chr 1:104,200,967...104,213,603
Ensembl chr 1:95,064,900...95,077,094

G

N-acetyltransferase 14

decreases expression

sulforaphane results in decreased expression of NAT14 mRNA

NCBI chr 1:77,939,430...77,941,950
Ensembl chr 1:68,910,601...68,912,733

G

neural cell adhesion molecule 2

decreases expression

sulforaphane results in decreased expression of NCAM2 mRNA

NCBI chr11:33,591,748...34,078,788
Ensembl chr11:20,104,925...20,591,984

G

NCCRP1, F-box associated domain containing

decreases expression

sulforaphane results in decreased expression of NCCRP1 mRNA

NCBI chr 1:92,962,618...92,966,155
Ensembl chr 1:83,835,083...83,838,676

G

neutrophil cytosolic factor 1

increases expression

sulforaphane results in increased expression of NCF1 mRNA

NCBI chr12:28,121,816...28,131,080
Ensembl chr12:22,485,451...22,494,646

G

neutrophil cytosolic factor 2

increases expression

sulforaphane results in increased expression of NCF2 mRNA

NCBI chr13:67,505,492...67,536,015
Ensembl chr13:64,955,503...64,986,277

G

nuclear receptor co-repressor 2

multiple interactions

sulforaphane inhibits the reaction [NCOR2 protein binds to NR1I2 protein]

NCBI chr12:37,127,736...37,289,612
Ensembl chr12:31,466,412...31,628,319

G

N-myc downstream regulated 1

increases expression

sulforaphane results in increased expression of NDRG1 mRNA

NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880

G

NDRG family member 3

decreases expression

sulforaphane results in decreased expression of NDRG3 mRNA

NCBI chr 3:166,007,556...166,070,981
Ensembl chr 3:145,548,041...145,650,873
Ensembl chr 3:145,548,041...145,650,873

G

NDRG family member 4

increases expression

sulforaphane results in increased expression of NDRG4 mRNA

NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,351,404...9,386,914

G

NADH:ubiquinone oxidoreductase subunit A1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of NDUFA1 mRNA

NCBI chr X:121,289,904...121,293,555
Ensembl chr X:116,424,223...116,428,633

G

NADH:ubiquinone oxidoreductase subunit A10

increases expression

sulforaphane results in increased expression of NDUFA10 mRNA

NCBI chr 9:100,454,498...100,490,023
Ensembl chr 9:93,007,042...93,042,560

G

NADH:ubiquinone oxidoreductase subunit A11

increases expression

sulforaphane results in increased expression of NDUFA11 mRNA

NCBI chr 9:1,637,614...1,641,673
Ensembl chr 9:1,550,468...1,555,601

G

NADH:ubiquinone oxidoreductase subunit A5

increases expression

sulforaphane results in increased expression of NDUFA5 mRNA

NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:52,995,546...53,005,598
Ensembl chr 5:52,995,546...53,005,598

G

NADH:ubiquinone oxidoreductase subunit A9

increases expression

sulforaphane results in increased expression of NDUFA9 mRNA

NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:159,659,242...159,688,018

G

NADH:ubiquinone oxidoreductase subunit AB1

increases expression

sulforaphane results in increased expression of NDUFAB1 mRNA

NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:176,644,703...176,658,099

G

NADH:ubiquinone oxidoreductase subunit B8

multiple interactions
increases expression

NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of NDUFB8 protein]]; sulforaphane promotes the reaction [Oxygen results in increased expression of NDUFB8 protein]
sulforaphane results in increased expression of NDUFB8 mRNA

NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:243,408,619...243,413,817

G

NADH:ubiquinone oxidoreductase subunit B9

increases expression

sulforaphane results in increased expression of NDUFB9 mRNA

NCBI chr 7:92,370,423...92,376,841
Ensembl chr 7:90,436,621...90,488,009

G

NADH:ubiquinone oxidoreductase core subunit S1

increases expression

sulforaphane results in increased expression of NDUFS1 mRNA

NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:64,546,225...64,579,893

G

NADH:ubiquinone oxidoreductase subunit V3

increases expression

sulforaphane results in increased expression of NDUFV3 mRNA

NCBI chr20:9,613,786...9,622,941
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

G

nebulette

decreases expression

sulforaphane results in decreased expression of NEBL mRNA

NCBI chr17:85,022,953...85,374,848
Ensembl chr17:80,118,543...80,466,210

G

N-terminal EF-hand calcium binding protein 2

increases expression

sulforaphane results in increased expression of NECAB2 mRNA

NCBI chr19:64,409,627...64,436,371
Ensembl chr19:47,501,302...47,527,684

G

nei-like DNA glycosylase 1

decreases expression

sulforaphane results in decreased expression of NEIL1 mRNA

NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:57,550,147...57,556,258

G

nei-like DNA glycosylase 3

increases expression

sulforaphane results in increased expression of NEIL3 mRNA

NCBI chr16:45,091,401...45,151,419
Ensembl chr16:38,359,371...38,418,527

G

NIMA-related kinase 2

increases expression

sulforaphane results in increased expression of NEK2 mRNA

NCBI chr13:105,936,809...105,950,054
Ensembl chr13:103,405,819...103,419,051

G

nestin

decreases expression

sulforaphane results in decreased expression of NES mRNA

NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:173,438,734...173,447,777

G

neurogenin 3

decreases expression

sulforaphane results in decreased expression of NEUROG3 mRNA

NCBI chr20:30,622,533...30,624,015
Ensembl chr20:30,079,780...30,081,262

G

NFE2 like bZIP transcription factor 2

multiple interactions
decreases response to substance
affects activity
increases response to substance
affects response to substance
affects localization
increases localization
decreases phosphorylation
increases activity
increases expression
decreases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of CCN2 protein]; [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of SERPINE1 protein]; [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of VCAM1 protein]; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of A4GALT mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAM19 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAMTS15 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADH7 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of AREG mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CALCR mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL11 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL20 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CHIA mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CYP26B1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DEDD2 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DNAJB1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FAM13C mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FRRS1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of GSTT1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of IZUMO4 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of KLRA16 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of KRTAP17-1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ME3 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of METAP1D mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MLIP mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MTR mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MYLK3 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of MYOZ2 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PLEKHJ1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PRMT8 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PTGS2 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PTPRG mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of S100G mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of SEC16B mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TINAG mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TLE6 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TRMT61B mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TUBB1 mRNA; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of USP2 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of NFE2L2; [sulforaphane co-treated with Dibutyl Phthalate] results in increased expression of NFE2L2 protein; Buthionine Sulfoximine affects the reaction [[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Acrolein]; Buthionine Sulfoximine affects the reaction [[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Chlorambucil]; Buthionine Sulfoximine inhibits the reaction [NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Acrolein]]; Buthionine Sulfoximine inhibits the reaction [NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Chlorambucil]]; Buthionine Sulfoximine inhibits the reaction [NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to cumene hydroperoxide]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of ABCC1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of ABCC1 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Oxygen] results in increased expression of COX1 protein]; NFE2L2 protein affects the reaction [Oxygen inhibits the reaction [sulforaphane results in increased expression of SDHB protein]]; NFE2L2 protein affects the reaction [sulforaphane affects the reaction [1,2-Dimethylhydrazine affects the expression of HDAC3 protein]]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Oxygen results in increased activity of RELA protein]]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Oxygen results in increased secretion of MUC5AC protein]]; NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of NDUFB8 protein]]; NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of PLN protein]]; NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of VDAC1 protein]]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of LAMP2 protein alternative form]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of PLN protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of SDHB protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of SQSTM1 protein]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to 1,2-naphthoquinone]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to 4-nitrobenzaldehyde]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Acrolein]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to allyl isothiocyanate]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to benzyl isothiocyanate]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Cadmium Chloride]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Chlorambucil]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to chromous chloride]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to cumene hydroperoxide]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Ethacrynic Acid]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to sodium arsenite]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to Vitamin K 3]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLC mRNA]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLM mRNA]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GSTA1 mRNA]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GSTM1 mRNA]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GSTP1 mRNA]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; sulforaphane affects the reaction [NFE2L2 affects the abundance of Glutathione]; sulforaphane affects the reaction [NFE2L2 protein affects the secretion of MUC5AC protein]; sulforaphane inhibits the reaction [[NFE2L2 protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of CDKN2A mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein modified form]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Oxygen affects the localization of NFE2L2 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Trichloroethylene results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Trichloroethylene results in decreased expression of NFE2L2 protein]; sulforaphane promotes the reaction [Methamphetamine results in increased expression of NFE2L2 protein]; sulforaphane results in increased expression of and affects the localization of NFE2L2 protein; sulforaphane results in increased expression of and results in increased phosphorylation of NFE2L2 protein
NFE2L2 gene mutant form results in decreased susceptibility to sulforaphane; NFE2L2 protein results in decreased susceptibility to sulforaphane
sulforaphane affects the activity of NFE2L2 protein
NFE2L2 protein results in increased susceptibility to sulforaphane; NFE2L2 results in increased susceptibility to sulforaphane
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to 1,2-naphthoquinone; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Acrolein; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to benzyl isothiocyanate; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Cadmium Chloride; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Carmustine; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Chlorambucil; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Cisplatin; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to cumene hydroperoxide; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Diamide; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Dinitrochlorobenzene; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Doxorubicin; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Ethacrynic Acid; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Hydrogen Peroxide; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Mercuric Chloride; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to sodium arsenite; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Vitamin K 3; [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to zinc chloride; [NFE2L2 protein affects the susceptibility to 1,2-Dimethylhydrazine] which affects the susceptibility to sulforaphane; [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the susceptibility to Oxygen deficiency; NFE2L2 affects the susceptibility to sulforaphane; NFE2L2 protein affects the susceptibility to sulforaphane
NFE2L2 protein mutant form results in increased susceptibility to sulforaphane; NFE2L2 protein results in increased susceptibility to sulforaphane
sulforaphane affects the localization of NFE2L2 mRNA; sulforaphane affects the localization of NFE2L2 protein
sulforaphane results in increased localization of NFE2L2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; [Buthionine Sulfoximine co-treated with sulforaphane] affects the expression of and affects the localization of NFE2L2 protein; [sulforaphane promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased activity of NFE2L2 protein]; Hydrocortisone inhibits the reaction [Hydrogen Peroxide promotes the reaction [sulforaphane results in increased expression of NFE2L2 protein]]; Hydrocortisone inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; Hydrocortisone inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Hydrogen Peroxide promotes the reaction [sulforaphane results in increased activity of NFE2L2 protein]; Hydrogen Peroxide promotes the reaction [sulforaphane results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; sulforaphane promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; sulforaphane promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; sulforaphane results in increased expression of and results in decreased degradation of NFE2L2 protein
sulforaphane results in decreased phosphorylation of NFE2L2 protein
sulforaphane results in increased expression of NFE2L2 mRNA; sulforaphane results in increased expression of NFE2L2 protein
sulforaphane results in increased expression of NFE2L2; sulforaphane results in increased expression of NFE2L2 mRNA; sulforaphane results in increased expression of NFE2L2 protein; sulforaphane results in increased expression of NFE2L2 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane affects the localization of NFE2L2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; [HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; [Hydrocortisone results in increased activity of NR3C1 protein] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]]; [sulforaphane results in increased activity of NFE2L2 protein] which results in decreased susceptibility to Cisplatin; [sulforaphane results in increased activity of NFE2L2 protein] which results in increased expression of CYP2A6 mRNA; [sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein] which results in decreased susceptibility to Benzo(a)pyrene; Acetylcysteine inhibits the reaction [sulforaphane affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased phosphorylation of and results in increased activity of NFE2L2 protein]; ammonium metavanadate affects the reaction [sulforaphane affects the localization of NFE2L2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased expression of NFE2L2 protein]; brusatol inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of and results in decreased activity of NFE2L2 protein]]; cyanoginosin LR promotes the reaction [sulforaphane affects the localization of NFE2L2 protein]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Dactinomycin inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; KEAP1 protein mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein]; KEAP1 protein promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of TXNRD1 protein]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AKR1C1 mRNA]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of ALDH2 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AR protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of CES1 mRNA alternative form]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of GCLM protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of HMOX1]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of TXNRD1 protein]; Reactive Oxygen Species affects the reaction [sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of HMOX1 protein]]; Staurosporine inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; sulforaphane affects the localization of and results in increased activity of NFE2L2 protein; sulforaphane affects the localization of and results in increased expression of NFE2L2 protein; sulforaphane binds to and results in increased activity of NFE2L2 protein; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of and results in decreased activity of NFE2L2 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased activity of NFE2L2 protein]; sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 mRNA]; sulforaphane promotes the reaction [3,3'-diindolylmethane results in increased expression of NFE2L2 protein]; sulforaphane promotes the reaction [[NFE2L2 protein binds to CES1 promoter] which results in increased expression of CES1 mRNA alternative form]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased activity of NFE2L2 protein]; sulforaphane promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; sulforaphane promotes the reaction [NFE2L2 protein binds to CES1 promoter]; sulforaphane promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer]; sulforaphane promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of HMOX1 protein]; sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA]; sulforaphane promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]; sulforaphane results in decreased ubiquitination of and results in increased expression of and affects the localization of NFE2L2 protein; sulforaphane results in increased expression of and affects the localization of NFE2L2 protein; sulforaphane results in increased expression of and results in decreased degradation of NFE2L2 protein; sulforaphane results in increased expression of and results in increased activity of NFE2L2 protein; sulforaphane results in increased phosphorylation of and results in increased activity of NFE2L2 protein
sulforaphane results in decreased expression of NFE2L2 protein

PMID:11309284 PMID:16890772 PMID:18385089 PMID:18417180 PMID:19071154 More...

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor I/A

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of NFIA mRNA

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:112,436,644...112,775,885

G

nuclear factor kappa B subunit 1

multiple interactions

sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of NFKB1 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFKB1 mRNA]; sulforaphane inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to RELA protein]]

PMID:16890772 PMID:19071154 PMID:34651546

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

multiple interactions
decreases expression

sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased phosphorylation of NFKBIA protein]; sulforaphane inhibits the reaction [Cyclosporine results in increased phosphorylation of NFKBIA protein]
sulforaphane results in decreased expression of NFKBIA mRNA
sulforaphane inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; sulforaphane inhibits the reaction [TNF protein affects the localization of NFKBIA protein]

PMID:19071154 PMID:23958496 PMID:31838189 PMID:35724838

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor beta

multiple interactions

sulforaphane inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein]

NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:84,046,295...84,053,862

G

NFKB inhibitor epsilon

decreases expression

sulforaphane results in decreased expression of NFKBIE mRNA

NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:15,436,941...15,450,437

G

NFKB inhibitor zeta

decreases expression

sulforaphane results in decreased expression of NFKBIZ mRNA

NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723

G

nerve growth factor

multiple interactions

NGF protein inhibits the reaction [sulforaphane results in decreased phosphorylation of AKT1 protein]; NGF protein inhibits the reaction [sulforaphane results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [sulforaphane results in increased expression of NGFR mRNA]; NGF protein inhibits the reaction [sulforaphane results in increased expression of NTRK1 mRNA]

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452

G

nerve growth factor receptor

multiple interactions
increases expression

NGF protein inhibits the reaction [sulforaphane results in increased expression of NGFR mRNA]

NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518

G

NHL repeat containing 2

decreases expression

sulforaphane results in decreased expression of NHLRC2 mRNA

NCBI chr 1:265,594,915...265,655,647
Ensembl chr 1:255,589,742...255,651,408

G

NHS-like 1

increases expression

sulforaphane results in increased expression of NHSL1 mRNA

NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:12,956,021...13,187,547

G

nipsnap homolog 3B

decreases expression

sulforaphane results in decreased expression of NIPSNAP3A mRNA

NCBI chr 5:67,637,644...67,669,698
Ensembl chr 5:67,614,036...67,669,700

G

NKD inhibitor of WNT signaling pathway 1

decreases expression

sulforaphane results in decreased expression of NKD1 mRNA

NCBI chr19:34,649,803...34,722,846
Ensembl chr19:18,476,344...18,549,380

G

NLR family, CARD domain containing 5

decreases expression

sulforaphane results in decreased expression of NLRC5 mRNA

NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,477,628...10,562,121

G

NLR family, pyrin domain containing 3

multiple interactions

sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NLRP3 protein]

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811

G

NME/NM23 nucleoside diphosphate kinase 1

affects binding

NME1 protein binds to sulforaphane

NCBI chr10:79,403,939...79,426,620
Ensembl chr10:78,906,083...78,916,408

G

NME/NM23 family member 5

increases expression

sulforaphane results in increased expression of NME5 mRNA

NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,163,555...26,180,794

G

nicotinamide nucleotide adenylyltransferase 1

increases expression

sulforaphane results in increased expression of NMNAT1 mRNA

NCBI chr 5:165,193,301...165,211,213
Ensembl chr 5:159,910,242...159,928,180

G

nicotinamide nucleotide adenylyltransferase 3

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of NMNAT3 mRNA

NCBI chr 8:107,771,124...107,888,528
Ensembl chr 8:98,873,398...99,020,645

G

nicotinamide N-methyltransferase

increases expression

sulforaphane results in increased expression of NNMT mRNA

NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:48,933,598...48,946,655

G

noggin

decreases expression

sulforaphane results in decreased expression of NOG mRNA

NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339

G

nitric oxide synthase 2

multiple interactions

sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; sulforaphane inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of NOS2 protein]

PMID:18838692 PMID:19071154 PMID:32073640

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

notch receptor 1

multiple interactions

sulforaphane inhibits the reaction [Gemcitabine results in increased expression of NOTCH1 protein]

NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 3

increases expression

sulforaphane results in increased expression of NOTCH3 mRNA

NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025

G

notch receptor 4

decreases expression

sulforaphane results in decreased expression of NOTCH4 mRNA

NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,160,445...4,184,465

G

NOTUM, palmitoleoyl-protein carboxylesterase

decreases expression

sulforaphane results in decreased expression of NOTUM mRNA

NCBI chr10:106,431,572...106,438,654
Ensembl chr10:105,933,249...105,940,315

G

NADPH oxidase 4

decreases expression

sulforaphane results in decreased expression of NOX4 mRNA

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406

G

NPC intracellular cholesterol transporter 1

decreases expression
increases expression

sulforaphane results in decreased expression of NPC1 mRNA
sulforaphane results in increased expression of NPC1 mRNA

PMID:30529165 PMID:31838189

NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,379,482...3,425,049

G

natriuretic peptide A

increases expression
multiple interactions

sulforaphane results in increased expression of NPPA mRNA
NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]

PMID:29353218 PMID:30529165

NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351

G

natriuretic peptide receptor 2

increases expression

sulforaphane results in increased expression of NPR2 mRNA

NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:57,883,171...57,901,580

G

natriuretic peptide receptor 3

decreases expression

sulforaphane results in decreased expression of NPR3 mRNA

NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:60,870,594...60,932,955

G

neuronal pentraxin 1

decreases expression

sulforaphane results in decreased expression of NPTX1 mRNA

PMID:30529165 PMID:31838189

NCBI chr10:105,309,578...105,318,829
Ensembl chr10:104,811,403...104,820,367

G

neuropeptide Y receptor Y4

decreases expression

sulforaphane results in decreased expression of NPY4R mRNA

NCBI chr16:9,474,051...9,475,307
Ensembl chr16:9,467,801...9,469,057

G

NAD(P)H quinone dehydrogenase 1

increases activity
multiple interactions
affects localization
increases expression
decreases expression

sulforaphane results in increased activity of NQO1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; [Streptozocin co-treated with sulforaphane] results in increased expression of NQO1; [sulforaphane co-treated with Acetaminophen] results in increased expression of NQO1 mRNA; [sulforaphane co-treated with Dibutyl Phthalate] results in increased expression of NQO1 protein; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 protein]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]; sulforaphane inhibits the reaction [fenamidone results in increased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of NQO1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; sulforaphane results in increased expression of and results in increased activity of NQO1 protein; Vanadium inhibits the reaction [sulforaphane affects the localization of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased activity of NQO1 protein]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Vanadium inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]
3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; ammonium metavanadate inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; ammonium metavanadate inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Cacodylic Acid promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; Cacodylic Acid promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; cyanoginosin LR promotes the reaction [sulforaphane results in increased expression of NQO1 protein]; Estradiol inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; monomethylarsonic acid promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; monomethylarsonic acid promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; sulforaphane inhibits the reaction [2,2-dichloroacetyl chloride results in decreased expression of NQO1 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of NQO1 mRNA]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of NQO1 mRNA]; sulforaphane promotes the reaction [Cisplatin results in increased expression of NQO1 mRNA]; sulforaphane results in increased expression of and results in increased activity of NQO1 protein; Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; trimethylarsine oxide promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; trimethylarsine oxide promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]
sulforaphane results in increased expression of NQO1; sulforaphane results in increased expression of NQO1 mRNA; sulforaphane results in increased expression of NQO1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; [Buthionine Sulfoximine co-treated with sulforaphane] results in increased expression of NQO1 protein; Hydrocortisone inhibits the reaction [Hydrogen Peroxide promotes the reaction [sulforaphane results in increased expression of NQO1 protein]]; Hydrocortisone inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Hydrocortisone inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]; Hydrogen Peroxide promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Hydrogen Peroxide promotes the reaction [sulforaphane results in increased expression of NQO1 protein]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of NQO1 protein]
sulforaphane metabolite results in increased expression of NQO1 mRNA; sulforaphane results in increased expression of NQO1 mRNA; sulforaphane results in increased expression of NQO1 protein
sulforaphane results in decreased expression of NQO1 mRNA

PMID:11264000 PMID:11309284 PMID:15672752 PMID:15896333 PMID:15906351 More...

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

increases expression

sulforaphane results in increased expression of NQO2 mRNA

NCBI chr17:31,114,825...31,144,062
Ensembl chr17:30,909,187...30,938,320

G

nuclear receptor subfamily 1, group D, member 2

increases expression

sulforaphane results in increased expression of NR1D2 mRNA

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
decreases expression
decreases activity

N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforaphane results in decreased expression of NR1I2 mRNA]; sulforaphane inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NR1I2 mRNA]; sulforaphane inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]
sulforaphane inhibits the reaction [3,3',4,5'-tetrahydroxystilbene results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [acacetin results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [alpha-methylepinine results in decreased expression of NR1I2 mRNA]; sulforaphane inhibits the reaction [Genistein results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; sulforaphane inhibits the reaction [Resveratrol results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
sulforaphane results in decreased activity of NR1I2 protein

PMID:21402137 PMID:21871945 PMID:29356861 PMID:29933105

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

[Hydrocortisone results in increased activity of NR3C1 protein] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]]

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor subfamily 4, group A, member 1

increases expression

sulforaphane results in increased expression of NR4A1 mRNA

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 4, group A, member 3

decreases expression

sulforaphane results in decreased expression of NR4A3 mRNA

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733

G

nuclear receptor subfamily 5, group A, member 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of NR5A2 mRNA

NCBI chr13:50,865,253...50,985,107
Ensembl chr13:48,316,301...48,433,326

G

neuronal regeneration related protein

decreases expression

sulforaphane results in decreased expression of NREP mRNA

PMID:26833863 PMID:31838189

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,017,083...25,046,591

G

nuclear respiratory factor 1

increases expression

sulforaphane results in increased expression of NRF1 protein

NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:58,664,957...58,825,328

G

neuregulin 1

increases expression

sulforaphane results in increased expression of NRG1 mRNA

NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884

G

neurexin 3

decreases expression

sulforaphane results in decreased expression of NRXN3 mRNA

NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:107,641,780...109,272,044

G

5'-nucleotidase domain containing 3

increases expression

sulforaphane results in increased expression of NT5DC3 mRNA

NCBI chr 7:23,078,078...23,134,899
Ensembl chr 7:21,190,554...21,247,374

G

neurotrophic receptor tyrosine kinase 1

multiple interactions
increases expression

NGF protein inhibits the reaction [sulforaphane results in increased expression of NTRK1 mRNA]

NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770

G

neurotrophic receptor tyrosine kinase 2

multiple interactions
increases expression

sulforaphane inhibits the reaction [Pyruvaldehyde results in decreased expression of NTRK2 protein]
sulforaphane results in increased expression of NTRK2 protein

NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136

G

NUAK family kinase 1

decreases expression

sulforaphane results in decreased expression of NUAK1 mRNA

NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:19,329,933...19,401,913

G

nudix hydrolase 7

decreases expression

sulforaphane results in decreased expression of NUDT7 mRNA

NCBI chr19:59,034,808...59,049,148
Ensembl chr19:42,125,711...42,151,081

G

nudix hydrolase 8

increases expression

sulforaphane results in increased expression of NUDT8 mRNA

NCBI chr 1:210,723,209...210,724,717
Ensembl chr 1:201,292,619...201,295,224

G

NUMB-like, endocytic adaptor protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of NUMBL mRNA

NCBI chr 1:91,677,437...91,701,415
Ensembl chr 1:82,550,054...82,573,776

G

nucleoporin 160

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of NUP160 mRNA

NCBI chr 3:97,120,723...97,183,227
Ensembl chr 3:76,665,786...76,724,565

G

nucleoredoxin-like 2

decreases expression

sulforaphane results in decreased expression of NXNL2 mRNA

NCBI chr17:14,182,849...14,187,595
Ensembl chr17:14,031,153...14,036,189

G

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2

decreases expression

sulforaphane results in decreased expression of NYAP2 mRNA

NCBI chr 9:89,855,109...90,133,466
Ensembl chr 9:82,406,827...82,653,498

G

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

increases expression

sulforaphane results in increased expression of OBSCN mRNA

NCBI chr10:44,273,686...44,419,275
Ensembl chr10:43,789,293...43,919,723

G

O-GlcNAcase

increases expression

sulforaphane results in increased expression of OGA mRNA

NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:244,598,292...244,634,359

G

osteoglycin

decreases expression

sulforaphane results in decreased expression of OGN mRNA

NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,032,069...15,052,739

G

olfactomedin 4

decreases expression

sulforaphane results in decreased expression of OLFM4 mRNA

NCBI chr15:61,790,889...61,838,773
Ensembl chr15:55,407,148...55,429,681

G

olfactomedin-like 1

decreases expression

sulforaphane results in decreased expression of OLFML1 mRNA

NCBI chr 1:170,889,912...170,914,300
Ensembl chr 1:161,478,242...161,502,537

G

olfactomedin-like 2A

decreases expression

sulforaphane results in decreased expression of OLFML2A mRNA

NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909

G

olfactomedin-like 2B

increases expression
decreases expression

sulforaphane results in increased expression of OLFML2B mRNA
sulforaphane results in decreased expression of OLFML2B mRNA

PMID:30529165 PMID:31838189

NCBI chr13:85,402,151...85,439,342
Ensembl chr13:82,869,433...82,906,607

G

oxidized low density lipoprotein receptor 1

decreases expression
increases expression

sulforaphane results in decreased expression of OLR1 mRNA
sulforaphane results in increased expression of OLR1 mRNA

PMID:30529165 PMID:35724838

NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:162,926,439...162,948,523

G

5-oxoprolinase (ATP-hydrolysing)

decreases expression

sulforaphane results in decreased expression of OPLAH mRNA

NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:108,011,475...108,035,297

G

opsin 3

increases expression

sulforaphane results in increased expression of OPN3 mRNA

NCBI chr13:90,121,560...90,152,076
Ensembl chr13:87,589,333...87,619,847

G

olfactory receptor family 2 subfamily H member 2C

increases expression

sulforaphane results in increased expression of OR2H2 mRNA

NCBI chr20:1,404,211...1,405,149
Ensembl chr20:1,395,108...1,400,441

G

olfactory receptor family 2 subfamily T member 47D

decreases expression

sulforaphane results in decreased expression of OR2T4 mRNA

NCBI chr10:43,383,531...43,384,493
Ensembl chr10:42,880,571...42,886,921
Ensembl chr10:42,880,571...42,886,921

G

orosomucoid 1

increases expression

sulforaphane results in increased expression of ORM1 mRNA

NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:76,772,941...76,776,154

G

oxysterol binding protein 2

decreases expression

sulforaphane results in decreased expression of OSBP2 mRNA

NCBI chr14:82,808,693...82,970,386
Ensembl chr14:78,585,089...78,746,786

G

oxysterol binding protein-like 6

increases expression

sulforaphane results in increased expression of OSBPL6 mRNA

NCBI chr 3:81,751,020...81,948,186
Ensembl chr 3:61,343,809...61,537,102

G

oxysterol binding protein-like 7

decreases expression

sulforaphane results in decreased expression of OSBPL7 mRNA

NCBI chr10:82,532,335...82,549,999
Ensembl chr10:82,036,042...82,053,557

G

oxidative stress induced growth inhibitor 1

increases expression

sulforaphane results in increased expression of OSGIN1 mRNA

NCBI chr19:64,380,336...64,409,165
Ensembl chr19:47,492,171...47,500,516

G

oxidative stress induced growth inhibitor family member 2

increases expression

sulforaphane results in increased expression of OSGIN2 mRNA

NCBI chr 5:29,500,406...29,519,340
Ensembl chr 5:29,500,408...29,520,831

G

osteoclastogenesis associated transmembrane protein 1

increases expression

sulforaphane results in increased expression of OSTM1 mRNA

NCBI chr20:47,653,696...47,769,248
Ensembl chr20:46,153,075...46,187,023

G

OTU deubiquitinase 7A

decreases expression

sulforaphane results in decreased expression of OTUD7A mRNA

NCBI chr 1:126,476,275...126,800,037
Ensembl chr 1:117,064,496...117,386,480

G

OTU deubiquitinase with linear linkage specificity like

decreases expression

sulforaphane results in decreased expression of OTULINL mRNA

NCBI chr 2:80,136,411...80,164,290
Ensembl chr 2:78,408,593...78,433,838

G

purinergic receptor P2X 3

decreases expression

sulforaphane results in decreased expression of P2RX3 mRNA

NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:70,080,851...70,125,178

G

purinergic receptor P2Y2

decreases expression

sulforaphane results in decreased expression of P2RY2 mRNA

NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:155,351,165...155,367,632

G

pyrimidinergic receptor P2Y6

decreases expression

sulforaphane results in decreased expression of P2RY6 mRNA

NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:155,295,111...155,330,808

G

prolyl 4-hydroxylase subunit beta

affects binding

P4HB protein binds to sulforaphane

NCBI chr10:106,335,300...106,346,911
Ensembl chr10:105,836,982...105,848,500

G

proton activated chloride channel 1

increases expression

sulforaphane results in increased expression of PACC1 mRNA

NCBI chr13:105,435,772...105,460,877
Ensembl chr13:102,894,612...102,929,770

G

peptidyl arginine deiminase 4

increases expression

sulforaphane results in increased expression of PADI4 mRNA

NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:153,041,352...153,074,362

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3

decreases expression

sulforaphane results in decreased expression of PAFAH1B3 mRNA

NCBI chr 1:90,009,085...90,011,611
Ensembl chr 1:80,881,309...80,883,893

G

paralemmin

decreases expression

sulforaphane results in decreased expression of PALM mRNA

NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:9,886,643...9,912,555

G

palmdelphin

decreases expression

sulforaphane results in decreased expression of PALMD mRNA

NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:204,889,533...204,941,519

G

pantothenate kinase 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PANK4 mRNA

NCBI chr 5:170,807,744...170,824,478
Ensembl chr 5:165,525,402...165,542,135

G

pannexin 2

increases expression

sulforaphane results in increased expression of PANX2 mRNA

NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:120,139,294...120,152,361

G

polyamine oxidase

decreases expression

sulforaphane results in decreased expression of PAOX mRNA

NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:194,903,273...194,928,504

G

3'-phosphoadenosine 5'-phosphosulfate synthase 1

decreases expression

sulforaphane results in decreased expression of PAPSS1 mRNA

NCBI chr 2:222,646,103...222,788,475
Ensembl chr 2:220,040,312...220,114,395

G

progestin and adipoQ receptor family member 9

increases expression

sulforaphane results in increased expression of PAQR9 mRNA

NCBI chr 8:104,993,884...104,996,180

G

par-3 family cell polarity regulator

decreases expression

sulforaphane results in decreased expression of PARD3 mRNA

NCBI chr19:71,977,420...72,527,273
Ensembl chr19:55,080,282...55,629,778

G

prostate androgen-regulated mucin-like protein 1

increases expression

sulforaphane results in increased expression of PARM1 mRNA

NCBI chr14:16,752,541...16,861,570
Ensembl chr14:16,468,459...16,577,314

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein]
[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein; [sulforaphane co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]
sulforaphane results in increased expression of PARP1 protein modified form

PMID:21684301 PMID:22922937 PMID:29792947 PMID:33894213

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

G

poly (ADP-ribose) polymerase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PARP2 mRNA

NCBI chr15:26,494,722...26,517,893
Ensembl chr15:24,034,106...24,044,338

G

PBX homeobox 1

decreases expression

sulforaphane results in decreased expression of PBX1 mRNA

NCBI chr13:82,811,664...83,121,447
Ensembl chr13:80,278,770...80,588,594

G

pyruvate carboxylase

decreases expression

sulforaphane results in decreased expression of PC mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:201,804,267...201,898,380

G

poly(rC) binding protein 4

decreases expression

sulforaphane results in decreased expression of PCBP4 mRNA

NCBI chr 8:115,971,751...115,981,987
Ensembl chr 8:107,093,013...107,103,276

G

protocadherin 10

decreases expression

sulforaphane results in decreased expression of PCDH10 mRNA

NCBI chr 2:130,553,432...130,619,591
Ensembl chr 2:128,617,174...128,677,190

G

protocadherin 7

increases expression

sulforaphane results in increased expression of PCDH7 mRNA

NCBI chr14:56,684,817...57,114,976
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051

G

protocadherin beta 15

decreases expression

sulforaphane results in decreased expression of PCDHB7 mRNA

NCBI chr18:29,454,334...29,457,872
Ensembl chr18:29,181,052...29,183,804

G

PC-esterase domain containing 1B

decreases expression

sulforaphane results in decreased expression of PCED1B mRNA

NCBI chr 7:130,273,531...130,451,727
Ensembl chr 7:128,391,319...128,528,231

G

phosphoenolpyruvate carboxykinase 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

sulforaphane results in increased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283

G

PCNA clamp associated factor

decreases expression

sulforaphane results in decreased expression of PCLAF mRNA

NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994

G

proliferating cell nuclear antigen

affects binding

PCNA protein binds to sulforaphane

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

PEST proteolytic signal containing nuclear protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PCNP mRNA

NCBI chr11:58,061,885...58,076,436
Ensembl chr11:44,592,742...44,607,348

G

procollagen C-endopeptidase enhancer

decreases expression

sulforaphane results in decreased expression of PCOLCE mRNA

NCBI chr12:24,720,972...24,727,287
Ensembl chr12:19,084,210...19,090,508

G

procollagen C-endopeptidase enhancer 2

decreases expression

sulforaphane results in decreased expression of PCOLCE2 mRNA

NCBI chr 8:105,073,086...105,130,725
Ensembl chr 8:96,193,461...96,251,114

G

Purkinje cell protein 4-like 1

increases expression

sulforaphane results in increased expression of PCP4L1 mRNA

NCBI chr13:86,121,463...86,145,097
Ensembl chr13:83,588,992...83,609,966

G

proprotein convertase subtilisin/kexin type 1

decreases expression

sulforaphane results in decreased expression of PCSK1 mRNA

NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:4,395,543...4,442,434

G

phosphodiesterase 1A

decreases expression

sulforaphane results in decreased expression of PDE1A mRNA

NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:64,747,269...65,024,874

G

phosphodiesterase 3A

decreases expression

sulforaphane results in decreased expression of PDE3A mRNA

NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:174,172,868...174,438,274

G

phosphodiesterase 4B

increases expression
decreases expression

sulforaphane results in increased expression of PDE4B mRNA
sulforaphane results in decreased expression of PDE4B mRNA

PMID:26833863 PMID:31838189

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696

G

phosphodiesterase 5A

decreases expression

sulforaphane results in decreased expression of PDE5A mRNA

NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:210,858,063...210,999,701

G

phosphodiesterase 7B

decreases expression

sulforaphane results in decreased expression of PDE7B mRNA

NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:15,182,704...15,492,900

G

phosphodiesterase 8B

decreases expression

sulforaphane results in decreased expression of PDE8B mRNA

PMID:30529165 PMID:31838189

NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:26,276,635...26,509,209

G

phosphodiesterase 9A

decreases expression

sulforaphane results in decreased expression of PDE9A mRNA

NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,469,848...9,562,948

G

platelet derived growth factor subunit B

increases expression

sulforaphane results in increased expression of PDGFB mRNA

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor C

increases expression

sulforaphane results in increased expression of PDGFC mRNA

NCBI chr 2:168,613,409...168,791,575
Ensembl chr 2:166,316,803...166,493,433

G

platelet derived growth factor receptor beta

decreases expression

sulforaphane results in decreased expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843

G

pyruvate dehydrogenase E1 subunit beta

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of PDHB mRNA

NCBI chr15:19,182,789...19,188,731
Ensembl chr15:16,750,980...16,758,500

G

PDZ and LIM domain 1

decreases expression

sulforaphane results in decreased expression of PDLIM1 mRNA

NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:239,042,385...239,091,076

G

PDZ domain containing 2

decreases expression

sulforaphane results in decreased expression of PDZD2 mRNA

NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:61,386,381...61,770,524

G

PDZK1 interacting protein 1

decreases expression

sulforaphane results in decreased expression of PDZK1IP1 mRNA

NCBI chr 5:128,618,050...128,623,131
Ensembl chr 5:128,618,237...128,623,131

G

paternally expressed 10

decreases expression

sulforaphane results in decreased expression of PEG10 mRNA

NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:32,848,493...32,852,621

G

pellino E3 ubiquitin protein ligase 1

increases expression

sulforaphane results in increased expression of PELI1 mRNA

NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285

G

proenkephalin

increases expression

sulforaphane results in increased expression of PENK mRNA

NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129

G

period circadian regulator 2

decreases expression

sulforaphane results in decreased expression of PER2 mRNA

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

increases expression

sulforaphane results in increased expression of PFKFB1 mRNA

NCBI chr X:22,936,038...22,989,691
Ensembl chr X:19,508,546...19,562,182

G

post-GPI attachment to proteins inositol deacylase 1

decreases expression

sulforaphane results in decreased expression of PGAP1 mRNA

NCBI chr 9:63,470,023...63,538,772
Ensembl chr 9:55,975,667...56,044,464

G

phosphogluconate dehydrogenase

increases expression

sulforaphane results in increased expression of PGD mRNA

PMID:26833863 PMID:31838189

NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:159,561,271...159,742,778

G

phosphoglucomutase 5

decreases expression

sulforaphane results in decreased expression of PGM5 mRNA

NCBI chr 1:231,752,052...231,939,812
Ensembl chr 1:222,325,643...222,513,437

G

phosphoglycolate phosphatase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PGP mRNA

NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,494,291...13,497,858

G

phosphatase and actin regulator 2

increases expression

sulforaphane results in increased expression of PHACTR2 mRNA

NCBI chr 1:9,411,412...9,680,648
Ensembl chr 1:7,597,927...7,860,289

G

phosphoglycerate dehydrogenase

increases expression

sulforaphane results in increased expression of PHGDH mRNA

PMID:30529165 PMID:31838189

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944

G

phosphorylase kinase regulatory subunit alpha 1

increases expression

sulforaphane results in increased expression of PHKA1 mRNA

NCBI chr X:71,639,701...71,778,465
Ensembl chr X:67,601,302...67,738,455

G

phosphohistidine phosphatase 1

decreases expression

sulforaphane results in decreased expression of PHPT1 mRNA

NCBI chr 3:28,791,062...28,792,905

G

phytanoyl-CoA 2-hydroxylase

increases expression

sulforaphane results in increased expression of PHYH mRNA

NCBI chr17:78,238,747...78,255,645
Ensembl chr17:73,329,082...73,346,409

G

phytanoyl-CoA 2-hydroxylase interacting protein

decreases expression

sulforaphane results in decreased expression of PHYHIP mRNA

NCBI chr15:51,943,670...51,954,921
Ensembl chr15:45,533,974...45,545,221

G

phosphatidylinositol 4-kinase beta

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PI4KB mRNA

NCBI chr 2:185,229,392...185,261,697
Ensembl chr 2:182,540,567...182,588,488

G

polymeric immunoglobulin receptor

increases expression

sulforaphane results in increased expression of PIGR mRNA

NCBI chr13:44,851,001...44,879,143
Ensembl chr13:42,298,914...42,326,875

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PIK3C2A mRNA

NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:170,577,942...170,683,472

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

decreases expression

sulforaphane results in decreased expression of PIK3CD mRNA

NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:160,094,952...160,120,930

G

phosphoinositide-3-kinase regulatory subunit 3

decreases expression

sulforaphane results in decreased expression of PIK3R3 mRNA

NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:129,701,229...129,772,583

G

paired immunoglobin-like type 2 receptor alpha

increases expression

sulforaphane results in increased expression of PILRA mRNA

NCBI chr12:23,452,626...23,464,772
Ensembl chr12:17,787,127...17,798,094

G

PTEN induced kinase 1

increases expression
decreases expression

sulforaphane results in increased expression of PINK1 mRNA
sulforaphane results in decreased expression of PINK1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635

G

phosphatidylinositol-4-phosphate 5-kinase type 1 beta

decreases expression

sulforaphane results in decreased expression of PIP5K1B mRNA

NCBI chr 1:231,331,836...231,610,092
Ensembl chr 1:221,914,159...222,183,672

G

pirin

increases expression

sulforaphane results in increased expression of PIR mRNA

NCBI chr X:33,740,428...33,851,049
Ensembl chr X:30,108,538...30,219,218

G

paired-like homeodomain 1

decreases expression

sulforaphane results in decreased expression of PITX1 mRNA

NCBI chr17:8,794,051...8,805,477
Ensembl chr17:8,794,134...8,800,291

G

paired-like homeodomain 3

increases methylation

sulforaphane results in increased methylation of PITX3 gene

NCBI chr 1:254,942,550...254,955,325
Ensembl chr 1:245,001,164...245,013,892

G

protein kinase domain containing, cytoplasmic

decreases expression

sulforaphane results in decreased expression of PKDCC mRNA

NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:11,455,686...11,465,556

G

cAMP-dependent protein kinase inhibitor gamma

decreases expression

sulforaphane results in decreased expression of PKIG mRNA

NCBI chr 3:172,749,871...172,817,514
Ensembl chr 3:152,366,041...152,398,082

G

pyruvate kinase L/R

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A2 group IB

decreases expression

sulforaphane results in decreased expression of PLA2G1B mRNA

NCBI chr12:46,802,932...46,814,511
Ensembl chr12:41,142,200...41,153,226

G

phospholipase A2 receptor 1

decreases expression

sulforaphane results in decreased expression of PLA2R1 mRNA

NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:44,883,943...45,013,660

G

phospholipase A and acyltransferase 3

increases expression

sulforaphane results in increased expression of PLAAT3 mRNA

NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:204,782,729...204,817,667

G

placenta associated 8

decreases expression

sulforaphane results in decreased expression of PLAC8 mRNA

NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,063,048...9,074,264

G

PLAC8-like 1

decreases expression

sulforaphane results in decreased expression of PLAC8L1 mRNA

NCBI chr18:34,419,873...34,452,414
Ensembl chr18:34,168,864...34,190,800

G

plasminogen activator, tissue type

decreases expression
multiple interactions

sulforaphane results in decreased expression of PLAT mRNA
sulforaphane results in decreased activity of and results in decreased secretion of PLAT protein

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223

G

plasminogen activator, urokinase

increases expression

sulforaphane results in increased expression of PLAU mRNA

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775

G

phospholipase C, epsilon 1

decreases expression

sulforaphane results in decreased expression of PLCE1 mRNA

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:236,244,683...236,551,438

G

phospholipase C, eta 2

decreases expression

sulforaphane results in decreased expression of PLCH2 mRNA

NCBI chr 5:170,826,543...170,885,012
Ensembl chr 5:165,544,200...165,602,356

G

phospholipase C-like 1

decreases expression

sulforaphane results in decreased expression of PLCL1 mRNA

NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:56,901,534...57,238,782

G

phospholipase D1

decreases expression

sulforaphane results in decreased expression of PLD1 mRNA

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:110,893,608...111,047,692

G

phospholipase D family, member 4

decreases expression

sulforaphane results in decreased expression of PLD4 mRNA

NCBI chr 6:137,639,948...137,647,462
Ensembl chr 6:131,818,860...131,826,376

G

phospholipase D family, member 6

increases expression

sulforaphane results in increased expression of PLD6 mRNA

NCBI chr10:45,078,081...45,080,732
Ensembl chr10:44,577,675...44,581,077

G

pleckstrin homology domain containing J1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PLEKHJ1 mRNA

NCBI chr 7:8,915,492...8,920,491

G

perilipin 4

increases expression

sulforaphane results in increased expression of PLIN4 mRNA

NCBI chr 9:1,016,334...1,025,249
Ensembl chr 9:929,176...938,056

G

perilipin 5

increases expression

sulforaphane results in increased expression of PLIN5 mRNA

NCBI chr 9:1,026,910...1,033,352
Ensembl chr 9:939,747...946,120

G

polo-like kinase 1

increases expression

sulforaphane results in increased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400

G

polo-like kinase 3

increases expression

sulforaphane results in increased expression of PLK3 mRNA

NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:130,607,142...130,612,317

G

phospholamban

increases expression
multiple interactions

sulforaphane results in increased expression of PLN mRNA; sulforaphane results in increased expression of PLN protein
NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of PLN protein]]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of PLN protein]; sulforaphane promotes the reaction [Oxygen results in increased expression of PLN protein]

NCBI chr20:33,166,512...33,182,241

G

phospholipid phosphatase 1

decreases expression

sulforaphane results in decreased expression of PLPP1 mRNA

NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:44,438,994...44,501,268

G

plexin domain containing 2

increases expression

sulforaphane results in increased expression of PLXDC2 mRNA

NCBI chr17:79,169,238...79,594,279
Ensembl chr17:79,196,369...79,585,282

G

prostate transmembrane protein, androgen induced 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PMEPA1 mRNA

NCBI chr 3:182,430,193...182,478,649
Ensembl chr 3:162,012,751...162,060,454

G

pregnancy up-regulated nonubiquitous CaM kinase

increases expression

sulforaphane results in increased expression of PNCK mRNA

NCBI chr X:156,520,751...156,524,828
Ensembl chr X:151,369,410...151,373,446

G

popeye domain cAMP effector 2

increases expression

sulforaphane results in increased expression of POPDC2 mRNA

NCBI chr11:75,850,068...75,897,094
Ensembl chr11:62,374,759...62,390,756

G

popeye domain cAMP effector 3

increases expression

sulforaphane results in increased expression of POPDC3 mRNA

NCBI chr20:50,354,775...50,383,050
Ensembl chr20:48,772,462...48,800,593

G

cytochrome p450 oxidoreductase

increases expression

sulforaphane results in increased expression of POR mRNA

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245

G

inorganic pyrophosphatase 1

increases expression

sulforaphane results in increased expression of PPA1 mRNA

NCBI chr20:30,132,088...30,160,492
Ensembl chr20:29,590,707...29,619,215

G

peroxisome proliferator-activated receptor gamma

increases expression
multiple interactions

sulforaphane results in increased expression of PPARG mRNA
sulforaphane inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]

PMID:26833863 PMID:36670177

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

increases expression

sulforaphane results in increased expression of PPARGC1A protein
sulforaphane results in increased expression of PPARGC1A mRNA

PMID:27993529 PMID:30529165

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656

G

PPARG coactivator 1 beta

increases expression

sulforaphane results in increased expression of PPARGC1B mRNA

NCBI chr18:57,029,264...57,131,466
Ensembl chr18:54,758,902...54,861,194

G

peptidylprolyl isomerase F

increases expression

sulforaphane results in increased expression of PPIF mRNA

NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,257,106...1,263,913

G

protein phosphatase 1, regulatory subunit 36

increases expression

sulforaphane results in increased expression of PPP1R36 mRNA

NCBI chr 6:100,874,397...100,894,764
Ensembl chr 6:95,139,007...95,159,102

G

protein phosphatase 1, regulatory subunit 3C

decreases expression

sulforaphane results in decreased expression of PPP1R3C mRNA

NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:234,460,652...234,465,961

G

protein phosphatase 1, regulatory subunit 9A

decreases expression

sulforaphane results in decreased expression of PPP1R9A mRNA

NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,024,450...33,286,907

G

protein phosphatase 2, regulatory subunit B, beta

decreases expression

sulforaphane results in decreased expression of PPP2R2B mRNA

NCBI chr18:34,904,686...35,357,299
Ensembl chr18:34,653,721...35,081,025

G

PR/SET domain 1

decreases expression

sulforaphane results in decreased expression of PRDM1 mRNA

PMID:30529165 PMID:31838189

NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488

G

PR/SET domain 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PRDM4 mRNA

NCBI chr 7:19,841,560...19,868,224
Ensembl chr 7:17,954,019...17,980,489

G

peroxiredoxin 1

increases expression
decreases methylation

sulforaphane results in increased expression of PRDX1 mRNA
sulforaphane results in decreased methylation of PRDX1 gene

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

affects binding

PRDX3 protein binds to sulforaphane

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:260,001,637...260,014,111

G

proline and arginine rich end leucine rich repeat protein

decreases expression

sulforaphane results in decreased expression of PRELP mRNA

NCBI chr13:47,920,480...47,943,547
Ensembl chr13:45,370,533...45,380,270

G

proteoglycan 2, pro eosinophil major basic protein

decreases expression

sulforaphane results in decreased expression of PRG2 mRNA

NCBI chr 3:90,469,192...90,472,759
Ensembl chr 3:70,062,535...70,066,101

G

prickle planar cell polarity protein 1

decreases expression

sulforaphane results in decreased expression of PRICKLE1 mRNA

NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:124,639,142...124,658,113

G

protein kinase AMP-activated catalytic subunit alpha 2

multiple interactions

sulforaphane inhibits the reaction [Carbon Monoxide results in decreased expression of PRKAA2 mRNA]

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:119,813,226...119,879,543

G

protein kinase AMP-activated non-catalytic subunit gamma 2

decreases expression

sulforaphane results in decreased expression of PRKAG2 mRNA

NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,010,890...10,252,142

G

protein kinase C, alpha

increases expression

sulforaphane results in increased expression of PRKCA mRNA

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012

G

protein kinase C, beta

increases expression

sulforaphane results in increased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536

G

protein kinase C, iota

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of PRKCI mRNA

NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:112,321,929...112,382,352

G

prolactin receptor

decreases expression

sulforaphane results in decreased expression of PRLR mRNA

NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718

G

protein arginine methyltransferase 8

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PRMT8 mRNA

NCBI chr 4:162,221,986...162,304,036
Ensembl chr 4:160,535,813...160,617,930

G

prominin 2

decreases expression

sulforaphane results in decreased expression of PROM2 mRNA

NCBI chr 3:135,200,944...135,215,130
Ensembl chr 3:114,747,654...114,761,787

G

peripherin

affects binding

PRPH protein binds to sulforaphane

NCBI chr 7:132,096,888...132,101,070
Ensembl chr 7:130,218,357...130,222,136

G

phosphoribosyl pyrophosphate synthetase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PRPS2 mRNA

NCBI chr X:30,592,845...30,630,127
Ensembl chr X:26,976,061...27,013,181

G

proline rich 14

decreases expression

sulforaphane results in decreased expression of PRR14 mRNA

NCBI chr 1:191,514,428...191,519,805
Ensembl chr 1:182,084,126...182,089,317

G

proline rich 5 like

decreases expression

sulforaphane results in decreased expression of PRR5L mRNA

NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:88,003,617...88,082,763

G

proline rich and Gla domain 4

decreases expression

sulforaphane results in decreased expression of PRRG4 mRNA

NCBI chr 3:111,669,508...111,698,205
Ensembl chr 3:91,214,653...91,243,273

G

paired related homeobox 2

decreases expression

sulforaphane results in decreased expression of PRRX2 mRNA

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:14,094,004...14,168,535

G

serine protease 56

decreases expression

sulforaphane results in decreased expression of PRSS56 mRNA

NCBI chr 9:95,289,984...95,307,877
Ensembl chr 9:87,854,805...87,859,978

G

proteinase 3

decreases expression

sulforaphane results in decreased expression of PRTN3 mRNA

NCBI chr 7:10,472,750...10,482,037
Ensembl chr 7:9,822,122...9,831,944

G

phosphoserine aminotransferase 1

increases expression

sulforaphane results in increased expression of PSAT1 mRNA

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit beta 6

multiple interactions

sulforaphane inhibits the reaction [epoxomicin results in increased expression of PSMB6 mRNA]

NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,239,241...55,241,586

G

proteasome 20S subunit beta 8

decreases expression

sulforaphane results in decreased expression of PSMB8 mRNA

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,652,159...4,655,283

G

PSMC3 interacting protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PSMC3IP mRNA

NCBI chr10:86,524,546...86,527,764
Ensembl chr10:86,023,950...86,027,423

G

proteasome 26S subunit, non-ATPase 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PSMD3 mRNA

NCBI chr10:84,139,249...84,151,879
Ensembl chr10:83,643,647...83,655,618

G

phosphotriesterase related

increases expression

sulforaphane results in increased expression of PTER mRNA

NCBI chr17:80,967,463...81,028,707
Ensembl chr17:76,058,503...76,119,627

G

prostaglandin D2 synthase

increases expression

sulforaphane results in increased expression of PTGDS mRNA

NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:8,281,899...8,284,833

G

prostaglandin E receptor 3

increases expression

sulforaphane results in increased expression of PTGER3 mRNA

NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434

G

prostaglandin E synthase 3 like

increases expression

sulforaphane results in increased expression of PTGES3L mRNA

NCBI chr10:86,354,019...86,361,318
Ensembl chr10:86,354,019...86,361,897

G

prostaglandin reductase 1

multiple interactions
increases expression

[sulforaphane co-treated with dibenzoylmethane] results in increased expression of PTGR1 mRNA
sulforaphane results in increased expression of PTGR1 mRNA

PMID:17942926 PMID:31838189

NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:73,784,009...73,802,666

G

prostaglandin-endoperoxide synthase 1

decreases expression

sulforaphane results in decreased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586

G

prostaglandin-endoperoxide synthase 2

decreases expression
multiple interactions

sulforaphane results in decreased expression of PTGS2 protein
sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PTGS2 mRNA; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]; sulforaphane inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]

PMID:17942926 PMID:19071154 PMID:24337631 PMID:30529165

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine kinase 2 beta

decreases expression

sulforaphane results in decreased expression of PTK2B mRNA

NCBI chr15:44,536,275...44,656,754
Ensembl chr15:40,360,723...40,481,282

G

PTOV1, extended AT-hook containing adaptor protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PTOV1 mRNA

NCBI chr 1:104,483,553...104,496,161
Ensembl chr 1:95,347,068...95,353,613

G

protein phosphatase 2 phosphatase activator

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PTPA mRNA

NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:13,689,741...13,722,549

G

protein tyrosine phosphatase, non-receptor type 12

increases expression

sulforaphane results in increased expression of PTPN12 mRNA

NCBI chr 4:14,913,071...14,985,084
Ensembl chr 4:14,021,052...14,092,927

G

protein tyrosine phosphatase, non-receptor type 22

increases expression

sulforaphane results in increased expression of PTPN22 mRNA

NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779

G

protein tyrosine phosphatase, receptor type, G

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of PTPRG mRNA

NCBI chr15:15,298,669...15,982,581
Ensembl chr15:12,871,721...13,554,094

G

PTTG1 regulator of sister chromatid separation, securin

increases expression

sulforaphane results in increased expression of PTTG1 mRNA

NCBI chr10:28,394,940...28,406,410
Ensembl chr10:27,893,689...27,904,837

G

pentraxin 3

increases expression

sulforaphane results in increased expression of PTX3 mRNA

NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:150,487,513...150,493,323

G

pseudouridine synthase 7

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PUS7 mRNA

NCBI chr 4:12,252,553...12,293,547
Ensembl chr 4:11,360,188...11,401,172

G

peroxisomal membrane protein 2

increases expression

sulforaphane results in increased expression of PXMP2 mRNA

NCBI chr12:52,053,951...52,064,283
Ensembl chr12:46,394,193...46,404,557

G

2-phosphoxylose phosphatase 1

decreases expression

sulforaphane results in decreased expression of PXYLP1 mRNA

NCBI chr 8:106,299,303...106,364,603
Ensembl chr 8:97,419,776...97,485,064

G

PYD and CARD domain containing

multiple interactions

sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PYCARD protein]

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955

G

glycogen phosphorylase B

increases expression
multiple interactions

sulforaphane results in increased expression of PYGB mRNA
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of PYGB mRNA

NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:139,611,749...139,663,553

G

glutaminyl-peptide cyclotransferase

increases expression

sulforaphane results in increased expression of QPCT mRNA

NCBI chr 6:21,716,824...21,748,895
Ensembl chr 6:15,964,657...15,996,711

G

glutamine rich 2

increases expression

sulforaphane results in increased expression of QRICH2 mRNA

NCBI chr10:102,168,103...102,196,497
Ensembl chr10:101,669,224...101,697,656

G

quiescin sulfhydryl oxidase 1

increases expression

sulforaphane results in increased expression of QSOX1 mRNA

NCBI chr13:70,500,060...70,537,711
Ensembl chr13:67,949,780...67,987,459

G

queuine tRNA-ribosyltransferase accessory subunit 2

decreases expression

sulforaphane results in decreased expression of QTRT2 mRNA

NCBI chr11:70,312,352...70,343,139
Ensembl chr11:56,806,385...56,837,228

G

RAB10, member RAS oncogene family

increases expression

sulforaphane results in increased expression of RAB10 mRNA

NCBI chr 6:31,974,858...32,039,554
Ensembl chr 6:26,266,859...26,320,193

G

RAB20, member RAS oncogene family

decreases expression

sulforaphane results in decreased expression of RAB20 mRNA

NCBI chr16:84,721,427...84,745,610
Ensembl chr16:78,019,337...78,043,529

G

RAB26, member RAS oncogene family

decreases expression

sulforaphane results in decreased expression of RAB26 mRNA

NCBI chr10:14,057,942...14,062,602
Ensembl chr10:13,553,395...13,558,030

G

RAB2B, member RAS oncogene family

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAB2B mRNA

NCBI chr15:27,441,860...27,462,479
Ensembl chr15:24,968,803...24,989,113

G

RAB3D, member RAS oncogene family

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAB3D mRNA

NCBI chr 8:28,714,706...28,725,379
Ensembl chr 8:20,439,294...20,449,185

G

RAB42, member RAS oncogene family

decreases expression

sulforaphane results in decreased expression of RAB42 mRNA

NCBI chr 5:149,781,181...149,782,851
Ensembl chr 5:144,496,215...144,498,848

G

RAB8B, member RAS oncogene family

increases expression

sulforaphane results in increased expression of RAB8B mRNA

NCBI chr 8:76,340,106...76,417,638
Ensembl chr 8:67,458,923...67,536,384

G

Rap associating with DIL domain

decreases expression

sulforaphane results in decreased expression of RADIL mRNA

NCBI chr12:17,137,872...17,202,021
Ensembl chr12:12,024,395...12,088,540

G

ribonucleic acid export 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAE1 mRNA

NCBI chr 3:182,197,432...182,212,381
Ensembl chr 3:161,779,088...161,794,038

G

ral guanine nucleotide dissociation stimulator like 1

decreases expression

sulforaphane results in decreased expression of RGL1 mRNA

NCBI chr13:67,184,402...67,454,019
Ensembl chr13:64,635,246...64,904,191

G

RAN guanine nucleotide release factor

increases expression

sulforaphane results in increased expression of RANGRF mRNA

NCBI chr10:54,176,325...54,177,696
Ensembl chr10:53,677,467...53,678,840

G

Rap1 GTPase-activating protein

increases expression

sulforaphane results in increased expression of RAP1GAP mRNA

NCBI chr 5:155,157,511...155,222,622
Ensembl chr 5:149,892,019...149,939,253

G

Rap guanine nucleotide exchange factor 4

decreases expression

sulforaphane results in decreased expression of RAPGEF4 mRNA

NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:56,809,270...57,102,316

G

Rap guanine nucleotide exchange factor 5

decreases expression

sulforaphane results in decreased expression of RAPGEF5 mRNA

NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:138,437,991...138,679,936

G

retinoic acid receptor responder 1

increases expression

sulforaphane results in increased expression of RARRES1 mRNA

NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:151,749,715...151,783,978

G

ras related dexamethasone induced 1

increases expression

sulforaphane results in increased expression of RASD1 mRNA

NCBI chr10:45,265,975...45,275,279
Ensembl chr10:44,766,455...44,768,186

G

RAS guanyl releasing protein 3

decreases expression

sulforaphane results in decreased expression of RASGRP3 mRNA

NCBI chr 6:25,647,386...25,745,952
Ensembl chr 6:19,895,390...19,958,578

G

RAS-like, family 10, member B

increases expression

sulforaphane results in increased expression of RASL10B mRNA

NCBI chr10:68,707,315...68,719,642
Ensembl chr10:68,210,275...68,220,376

G

RAS-like family 11 member A

decreases expression

sulforaphane results in decreased expression of RASL11A mRNA

NCBI chr12:13,372,023...13,374,784
Ensembl chr12:8,258,159...8,262,576

G

Ras association domain family member 2

decreases expression

sulforaphane results in decreased expression of RASSF2 mRNA

NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:119,245,821...119,280,431

G

Ras association domain family member 5

decreases expression

sulforaphane results in decreased expression of RASSF5 mRNA

NCBI chr13:45,189,768...45,255,277
Ensembl chr13:42,637,549...42,703,024

G

RB transcriptional corepressor 1

increases phosphorylation

sulforaphane results in increased phosphorylation of RB1 protein

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302

G

RB binding protein 4, chromatin remodeling factor

affects binding

RBBP4 protein binds to sulforaphane

NCBI chr 5:146,940,207...146,959,501
Ensembl chr 5:141,638,421...141,675,284
Ensembl chr 2:141,638,421...141,675,284

G

RB binding protein 8, endonuclease

increases acetylation

Sulforaphane increases acetylation of RBBP8 protein in colon cancer cells

RGD

NCBI chr18:3,198,188...3,263,643
Ensembl chr18:2,921,286...2,988,846

G

RB binding protein 9, serine hydrolase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RBBP9 mRNA

NCBI chr 3:152,378,426...152,392,370
Ensembl chr 3:131,925,341...131,932,156

G

RNA binding motif protein 20

increases expression

sulforaphane results in increased expression of RBM20 mRNA

NCBI chr 1:262,671,311...262,912,551
Ensembl chr 1:252,683,771...252,886,060

G

RNA binding motif protein 24

increases expression

sulforaphane results in increased expression of RBM24 mRNA

NCBI chr17:18,481,893...18,494,440
Ensembl chr17:18,275,688...18,288,102

G

RNA binding motif protein 47

increases expression

sulforaphane results in increased expression of RBM47 mRNA

NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,154,142...42,189,431

G

RNA binding motif protein 48

decreases expression

sulforaphane results in decreased expression of RBM48 mRNA

NCBI chr 4:30,559,063...30,569,409
Ensembl chr 4:30,559,087...30,569,406

G

RNA binding motif, single stranded interacting protein 3

decreases expression

sulforaphane results in decreased expression of RBMS3 mRNA

NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:116,309,882...117,625,423

G

retinol binding protein 7

increases expression

sulforaphane results in increased expression of RBP7 mRNA

NCBI chr 5:165,169,700...165,177,427
Ensembl chr 5:159,889,723...159,894,339

G

recombination signal binding protein for immunoglobulin kappa J region-like

decreases expression

sulforaphane results in decreased expression of RBPJL mRNA

NCBI chr 3:173,553,389...173,565,869
Ensembl chr 3:153,134,140...153,146,513

G

regulator of calcineurin 2

decreases expression

sulforaphane results in decreased expression of RCAN2 mRNA

NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:16,959,480...17,174,856

G

REST corepressor 2

decreases expression

sulforaphane results in decreased expression of RCOR2 mRNA

NCBI chr 1:213,882,585...213,890,022
Ensembl chr 1:204,454,360...204,460,838

G

retinol dehydrogenase 10

decreases expression

sulforaphane results in decreased expression of RDH10 mRNA

NCBI chr 5:7,969,931...7,998,834
Ensembl chr 5:3,188,445...3,215,572

G

receptor accessory protein 4

increases expression

sulforaphane results in increased expression of REEP4 mRNA

NCBI chr15:52,030,022...52,033,229
Ensembl chr15:45,619,941...45,623,526

G

receptor accessory protein 6

decreases expression

sulforaphane results in decreased expression of REEP6 mRNA

NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:9,373,927...9,380,597

G

REL proto-oncogene, NF-kB subunit

multiple interactions
decreases expression

sulforaphane promotes the reaction [Gemcitabine results in decreased expression of REL protein]
sulforaphane results in decreased expression of REL protein

NCBI chr14:101,891,238...101,922,324
Ensembl chr14:97,695,161...97,720,892

G

RELA proto-oncogene, NF-kB subunit

affects expression
increases expression
multiple interactions

sulforaphane affects the expression of RELA protein
sulforaphane results in increased expression of RELA protein
NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Oxygen results in increased activity of RELA protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; sulforaphane inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to RELA protein]]; sulforaphane inhibits the reaction [Oxygen results in increased activity of RELA protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of and results in increased phosphorylation of RELA protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of RELA protein modified form]
sulforaphane inhibits the reaction [IL1B protein affects the localization of RELA protein]; sulforaphane inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to RELA protein]]; sulforaphane inhibits the reaction [TNF protein affects the localization of RELA protein]

PMID:15090468 PMID:16890772 PMID:17898303 PMID:19071154 PMID:30529165 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

RRAD and GEM like GTPase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of REM1 mRNA

NCBI chr 3:161,563,984...161,572,478
Ensembl chr 3:141,103,766...141,112,203

G

RAS-like, estrogen-regulated, growth-inhibitor

decreases expression

sulforaphane results in decreased expression of RERG mRNA

NCBI chr 4:171,712,794...171,821,268
Ensembl chr 4:169,982,279...170,089,715

G

resistin

increases expression

sulforaphane results in increased expression of RETN mRNA

PMID:26833863 PMID:30529165

NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620

G

REV1, DNA directed polymerase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of REV1 mRNA

NCBI chr 9:47,773,907...47,847,554
Ensembl chr 9:40,278,101...40,351,576

G

refilin B

increases expression

sulforaphane results in increased expression of RFLNB mRNA

NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976

G

regulator of G-protein signaling 2

decreases expression

sulforaphane results in decreased expression of RGS2 mRNA

NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385

G

regulator of G-protein signaling 5

increases expression

sulforaphane results in increased expression of RGS5 mRNA

NCBI chr13:84,381,077...84,417,875
Ensembl chr13:81,836,304...81,885,518

G

rhomboid 5 homolog 2

increases expression

sulforaphane results in increased expression of RHBDF2 mRNA

NCBI chr10:102,331,991...102,359,117
Ensembl chr10:101,833,157...101,860,283

G

rhomboid like 1

increases expression

sulforaphane results in increased expression of RHBDL1 mRNA

NCBI chr10:15,359,027...15,362,530
Ensembl chr10:14,854,514...14,857,430

G

RHEB like 1

increases expression

sulforaphane results in increased expression of RHEBL1 mRNA

NCBI chr 7:131,905,207...131,910,088
Ensembl chr 7:130,026,341...130,030,248

G

rhodopsin

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RHO mRNA

NCBI chr 4:150,653,205...150,658,367
Ensembl chr 4:148,980,611...148,985,773

G

ras homolog family member B

decreases expression

sulforaphane results in decreased expression of RHOB mRNA

NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:31,363,548...31,366,108

G

ras homolog family member F, filopodia associated

decreases expression

sulforaphane results in decreased expression of RHOF mRNA

NCBI chr12:39,082,413...39,107,528
Ensembl chr12:33,431,280...33,446,703

G

ras homolog family member U

decreases expression

sulforaphane results in decreased expression of RHOU mRNA

NCBI chr19:68,538,960...68,548,733
Ensembl chr19:51,641,227...51,650,552

G

ras homolog family member V

decreases expression

sulforaphane results in decreased expression of RHOV mRNA

NCBI chr 3:126,714,608...126,723,617
Ensembl chr 3:106,260,776...106,269,479

G

rhophilin, Rho GTPase binding protein 1

decreases expression

sulforaphane results in decreased expression of RHPN1 mRNA

NCBI chr 7:109,272,676...109,283,444
Ensembl chr 7:107,391,984...107,402,713

G

RNA sensor RIG-1

increases expression

sulforaphane results in increased expression of RIGI mRNA

NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819

G

Rab interacting lysosomal protein-like 1

increases expression

sulforaphane results in increased expression of RILPL1 mRNA

NCBI chr12:37,732,847...37,770,659
Ensembl chr12:32,071,693...32,109,938

G

Ras and Rab interactor-like

decreases expression

sulforaphane results in decreased expression of RINL mRNA

NCBI chr 1:93,204,543...93,215,851
Ensembl chr 1:84,077,265...84,088,330

G

Ras-like without CAAX 1

increases expression

sulforaphane results in increased expression of RIT1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 2:176,478,616...176,493,269
Ensembl chr 2:174,180,848...174,195,455

G

ribonuclease A family member 3

decreases expression

sulforaphane results in decreased expression of EAR1 mRNA

NCBI chr15:26,985,399...26,986,269
Ensembl chr15:24,511,891...24,512,790

G

ring finger protein 103

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of RNF103 mRNA

NCBI chr 4:105,084,762...105,100,839
Ensembl chr 4:103,526,502...103,555,919

G

ring finger protein 112

increases expression

sulforaphane results in increased expression of RNF112 mRNA

NCBI chr10:46,620,602...46,655,745
Ensembl chr10:46,121,148...46,126,699

G

ring finger protein 128

increases expression

sulforaphane results in increased expression of RNF128 mRNA

NCBI chr X:107,968,973...108,087,037
Ensembl chr X:103,183,831...103,298,423

G

ring finger protein 144B

decreases expression

sulforaphane results in decreased expression of RNF144B mRNA

NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,432,786...17,562,760

G

ring finger protein 150

decreases expression

sulforaphane results in decreased expression of RNF150 mRNA

NCBI chr19:41,912,276...42,133,217
Ensembl chr19:25,006,611...25,228,678

G

ring finger protein 182

decreases expression

sulforaphane results in decreased expression of RNF182 mRNA

NCBI chr17:21,232,084...21,287,329
Ensembl chr17:21,030,214...21,094,911

G

RNA-binding region (RNP1, RRM) containing 3

decreases expression

sulforaphane results in decreased expression of RNPC3 mRNA

NCBI chr 2:204,121,191...204,145,128
Ensembl chr 2:201,432,684...201,456,747

G

rogdi atypical leucine zipper

decreases expression

sulforaphane results in decreased expression of ROGDI mRNA

NCBI chr10:11,074,288...11,078,907
Ensembl chr10:10,567,834...10,572,452

G

RAR-related orphan receptor C

decreases expression

sulforaphane results in decreased expression of RORC mRNA

NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:182,009,286...182,034,907

G

ribosomal protein L7A

decreases expression

sulforaphane results in decreased expression of RPL7A mRNA

NCBI chr 3:30,637,136...30,639,778
Ensembl chr 3:10,239,001...10,241,716
Ensembl chr18:10,239,001...10,241,716

G

reprimo, TP53 dependent G2 arrest mediator homolog

decreases expression

sulforaphane results in decreased expression of RPRM mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:58,948,618...58,950,035
Ensembl chr 3:38,539,581...38,540,998

G

ribosomal protein S6

multiple interactions

sulforaphane inhibits the reaction [INS protein results in increased phosphorylation of RPS6 protein]

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602

G

ribosomal protein SA

affects binding

RPSA protein binds to sulforaphane

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

sulforaphane results in increased expression of RRAD mRNA

NCBI chr19:360,581...363,874
Ensembl chr19:354,198...357,417

G

R-spondin 3

increases expression

sulforaphane results in increased expression of RSPO3 mRNA

NCBI chr 1:30,112,529...30,197,267
Ensembl chr 1:28,283,914...28,367,061

G

arginine and serine rich coiled-coil 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of RSRC1 mRNA

NCBI chr 2:153,536,839...153,942,825
Ensembl chr 2:151,231,156...151,632,765

G

RT1 class II, locus Da

decreases expression

sulforaphane results in decreased expression of HLA-DRA mRNA

NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,512,911...4,518,455

G

RT1 class II, locus DMa

decreases expression

sulforaphane results in decreased expression of HLA-DMA mRNA

NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,707,028...4,710,432

G

RT1 class II, locus Ha

decreases expression

sulforaphane results in decreased expression of HLA-DPA1 mRNA

NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,760,118...4,770,244

G

RT1 class II, locus Hb, pseudogene 1

decreases expression

sulforaphane results in decreased expression of HLA-DPB1 mRNA

NCBI chr20:4,777,494...4,781,486
Ensembl chr20:4,774,650...4,780,618

G

RT1 class Ib, locus M3, gene 1

decreases expression

sulforaphane results in decreased expression of HLA-G mRNA

NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,287,521...1,328,117

G

reticulon 2

decreases expression

sulforaphane results in decreased expression of RTN2 mRNA

NCBI chr 1:88,063,124...88,076,082
Ensembl chr 1:78,935,104...78,948,069

G

relaxin family peptide receptor 1

decreases expression

sulforaphane results in decreased expression of RXFP1 mRNA

NCBI chr 2:167,070,414...167,191,616
Ensembl chr 2:164,774,799...164,893,412

G

retinoid X receptor gamma

increases expression

sulforaphane results in increased expression of RXRG mRNA

NCBI chr13:82,276,330...82,318,097
Ensembl chr13:79,743,563...79,785,167

G

ryanodine receptor 2

increases expression
decreases expression

sulforaphane results in increased expression of RYR2 mRNA
sulforaphane results in decreased expression of RYR2 mRNA

PMID:30529165 PMID:31838189

NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142

G

S100 calcium binding protein A1

increases expression

sulforaphane results in increased expression of S100A1 mRNA

NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:175,993,922...175,999,544

G

S100 calcium-binding protein A4

decreases expression

sulforaphane results in decreased expression of S100A4 mRNA

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:176,091,804...176,093,254

G

S100 calcium binding protein A8

increases expression

sulforaphane results in increased expression of S100A8 mRNA

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

increases expression

sulforaphane results in increased expression of S100A9 mRNA

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230

G

S100 calcium binding protein G

multiple interactions
decreases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of S100G mRNA
sulforaphane results in decreased expression of S100G mRNA

NCBI chr X:35,337,636...35,340,205
Ensembl chr X:31,705,866...31,708,433

G

sphingosine-1-phosphate receptor 1

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of S1PR1 mRNA
sulforaphane results in decreased expression of S1PR1 mRNA

NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:203,621,587...203,629,681

G

sphingosine-1-phosphate receptor 5

decreases expression

sulforaphane results in decreased expression of S1PR5 mRNA

NCBI chr 8:28,062,841...28,068,013
Ensembl chr 8:19,786,663...19,791,795

G

spalt-like transcription factor 4

decreases expression

sulforaphane results in decreased expression of SALL4 mRNA

NCBI chr 3:177,891,705...177,909,743
Ensembl chr 3:157,474,642...157,490,822

G

sterile alpha motif domain containing 11

decreases expression

sulforaphane results in decreased expression of SAMD11 mRNA

NCBI chr 5:172,113,900...172,142,026
Ensembl chr 5:166,831,663...166,850,009

G

sterile alpha motif domain containing 4A

decreases expression

sulforaphane results in decreased expression of SAMD4A mRNA

NCBI chr15:22,616,200...22,831,872
Ensembl chr15:20,134,377...20,348,380

G

suppressor APC domain containing 2

increases expression

sulforaphane results in increased expression of SAPCD2 mRNA

NCBI chr 3:28,583,615...28,590,694
Ensembl chr 3:8,187,266...8,192,546

G

seryl-tRNA synthetase 2, mitochondrial

decreases expression

sulforaphane results in decreased expression of SARS2 mRNA

NCBI chr 1:93,156,514...93,171,943
Ensembl chr 1:84,028,986...84,040,725

G

spermidine/spermine N1-acetyl transferase 1

increases expression

sulforaphane results in increased expression of SAT1 mRNA

NCBI chr X:44,008,089...44,011,376
Ensembl chr X:40,157,046...40,196,813

G

SATB homeobox 1

increases methylation
decreases expression

sulforaphane results in increased methylation of SATB1 gene
sulforaphane results in decreased expression of SATB1 mRNA

NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,680,920...4,753,251

G

stabilizer of axonemal microtubules 4

increases expression

sulforaphane results in increased expression of SAXO4 mRNA

NCBI chr 1:216,538,735...216,548,195
Ensembl chr 1:207,113,809...207,122,358

G

scavenger receptor class A, member 3

increases expression

sulforaphane results in increased expression of SCARA3 mRNA

NCBI chr15:44,315,422...44,348,416
Ensembl chr15:40,140,161...40,172,894

G

scavenger receptor class A, member 5

increases expression

sulforaphane results in increased expression of SCARA5 mRNA

NCBI chr15:44,055,576...44,160,593
Ensembl chr15:39,880,035...39,983,373

G

stearoyl-CoA desaturase

decreases expression

sulforaphane results in decreased expression of SCD mRNA

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562

G

stearoyl-Coenzyme A desaturase 2

decreases expression

sulforaphane results in decreased expression of SCD2 mRNA

NCBI chr 1:253,118,377...253,131,436
Ensembl chr 1:243,169,236...243,182,232

G

sciellin

decreases expression

sulforaphane results in decreased expression of SCEL mRNA

NCBI chr15:86,754,595...86,871,200
Ensembl chr15:80,339,951...80,456,372

G

secretogranin II

increases expression

sulforaphane results in increased expression of SCG2 mRNA

NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:80,803,075...80,821,097

G

scinderin

increases expression

sulforaphane results in increased expression of SCIN mRNA

NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:57,109,403...57,188,242

G

sodium voltage-gated channel alpha subunit 1

decreases expression

sulforaphane results in decreased expression of SCN1A mRNA

NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:50,952,791...51,071,699

G

sodium voltage-gated channel alpha subunit 5

increases expression

sulforaphane results in increased expression of SCN5A mRNA

NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769

G

sodium channel epithelial 1 subunit alpha

decreases expression

sulforaphane results in decreased expression of SCNN1A mRNA

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:158,122,962...158,146,181

G

syndecan 2

decreases expression

sulforaphane results in decreased expression of SDC2 mRNA

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:64,127,110...64,241,081

G

syndecan binding protein

increases expression

sulforaphane results in increased expression of SDCBP mRNA

NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:19,489,961...19,527,572

G

SDE2 telomere maintenance homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SDE2 mRNA

NCBI chr13:95,110,598...95,126,929
Ensembl chr13:92,578,874...92,595,140

G

succinate dehydrogenase complex iron sulfur subunit B

multiple interactions
increases expression

NFE2L2 protein affects the reaction [Oxygen inhibits the reaction [sulforaphane results in increased expression of SDHB protein]]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of SDHB protein]; Oxygen inhibits the reaction [sulforaphane results in increased expression of SDHB protein]
sulforaphane results in increased expression of SDHB mRNA; sulforaphane results in increased expression of SDHB protein

NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:153,264,899...153,314,293

G

sidekick cell adhesion molecule 2

decreases expression

sulforaphane results in decreased expression of SDK2 mRNA

NCBI chr10:99,324,047...99,601,683
Ensembl chr10:98,828,348...99,101,759

G

short chain dehydrogenase/reductase family 16C, member 5

decreases expression

sulforaphane results in decreased expression of SDR16C5 mRNA

NCBI chr 5:21,816,394...21,841,596
Ensembl chr 5:17,018,813...17,040,970

G

SEC16 homolog B, endoplasmic reticulum export factor

decreases expression
multiple interactions

sulforaphane results in decreased expression of SEC16B mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of SEC16B mRNA

NCBI chr13:72,206,778...72,260,733
Ensembl chr13:69,684,291...69,727,196

G

SECIS binding protein 2-like

decreases expression

sulforaphane results in decreased expression of SECISBP2L mRNA

NCBI chr 3:133,443,023...133,489,467
Ensembl chr 3:112,991,908...113,035,884

G

SEL1L family member 3

increases expression

sulforaphane results in increased expression of SEL1L3 mRNA

NCBI chr14:61,988,350...62,095,542
Ensembl chr14:57,775,501...57,882,644

G

selenium binding protein 1

decreases expression

sulforaphane results in decreased expression of SELENBP1 mRNA

NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:182,493,978...182,504,594

G

selenoprotein H

decreases expression

sulforaphane results in decreased expression of SELENOH mRNA

NCBI chr 3:90,158,541...90,160,108
Ensembl chr 3:69,752,757...69,753,417

G

selenoprotein M

decreases expression

sulforaphane results in decreased expression of SELENOM mRNA

NCBI chr14:82,619,453...82,622,056
Ensembl chr14:78,395,826...78,398,429

G

selenoprotein P

decreases expression

sulforaphane results in decreased expression of SELENOP mRNA

NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852

G

selectin P

increases expression

sulforaphane results in increased expression of SELP mRNA

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845

G

semaphorin 3B

decreases expression

sulforaphane results in decreased expression of SEMA3B mRNA

NCBI chr 8:117,150,307...117,161,570
Ensembl chr 8:108,271,666...108,282,919

G

semaphorin 3C

decreases expression

sulforaphane results in decreased expression of SEMA3C mRNA

NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:17,583,212...17,746,534

G

semaphorin 3F

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SEMA3F mRNA

NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:108,357,629...108,387,083

G

semaphorin 7A (John Milton Hagen blood group)

decreases expression

sulforaphane results in decreased expression of SEMA7A mRNA

NCBI chr 8:67,244,318...67,267,060
Ensembl chr 8:58,348,448...58,370,536

G

septin 3

decreases expression

sulforaphane results in decreased expression of SEPTIN3 mRNA

NCBI chr 7:115,659,414...115,691,173
Ensembl chr 7:113,783,095...113,811,087

G

septin 6

decreases expression

sulforaphane results in decreased expression of SEPTIN6 mRNA

PMID:26833863 PMID:31838189

NCBI chr X:121,018,951...121,157,677
Ensembl chr X:116,153,255...116,230,115

G

serine incorporator 5

decreases expression

sulforaphane results in decreased expression of SERINC5 mRNA

NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346

G

serpin family E member 1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of SERPINE1 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein]

PMID:24967692 PMID:29353218 PMID:30096613

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657

G

serpin family E member 2

increases expression

sulforaphane results in increased expression of SERPINE2 mRNA

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826

G

serpin family G member 1

affects binding

SERPING1 protein binds to sulforaphane

NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:69,842,739...69,852,034

G

SEC14 and spectrin domain containing 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SESTD1 mRNA

NCBI chr 3:82,530,796...82,627,960
Ensembl chr 3:62,129,887...62,220,546

G

splicing factor 3b, subunit 5

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SF3B5 mRNA

NCBI chr 1:9,177,189...9,177,901
Ensembl chr 1:7,350,731...7,357,839

G

stratifin

affects binding

SFN protein binds to sulforaphane

NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314

G

secreted frizzled-related protein 1

increases expression

sulforaphane results in increased expression of SFRP1 mRNA

NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286

G

sarcoglycan, alpha

increases expression

sulforaphane results in increased expression of SGCA mRNA

NCBI chr10:80,397,158...80,416,165
Ensembl chr10:79,908,738...79,922,813

G

serum/glucocorticoid regulated kinase 1

increases expression

sulforaphane results in increased expression of SGK1 mRNA

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:22,980,261...23,098,283

G

sphingomyelin synthase 2

increases expression

sulforaphane results in increased expression of SGMS2 mRNA

NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:219,893,572...219,967,546

G

shugoshin 2

increases expression

sulforaphane results in increased expression of SGO2 mRNA

NCBI chr 9:67,032,083...67,067,439
Ensembl chr 9:59,548,683...59,573,229

G

sphingosine-1-phosphate phosphatase 2

decreases expression

sulforaphane results in decreased expression of SGPP2 mRNA

NCBI chr 9:87,211,155...87,331,787
Ensembl chr 9:79,763,284...79,880,457

G

SH2 domain containing 5

increases expression

sulforaphane results in increased expression of SH2D5 mRNA

NCBI chr 5:155,753,087...155,763,936
Ensembl chr 5:150,467,728...150,479,955

G

SH3 domain containing 19

decreases expression

sulforaphane results in decreased expression of SH3D19 mRNA

NCBI chr 2:173,654,234...173,814,030
Ensembl chr 2:171,356,251...171,515,561

G

SH3 and PX domains 2A

decreases expression
increases methylation

sulforaphane results in decreased expression of SH3PXD2A mRNA
sulforaphane results in increased methylation of SH3PXD2A gene

NCBI chr 1:256,094,991...256,301,120
Ensembl chr 1:246,160,502...246,360,166

G

SH3 domain containing ring finger 3

increases expression

sulforaphane results in increased expression of SH3RF3 mRNA

NCBI chr20:27,306,937...27,642,315
Ensembl chr20:26,765,015...27,099,257

G

SH3 domain and tetratricopeptide repeats 2

increases expression

sulforaphane results in increased expression of SH3TC2 mRNA

NCBI chr18:57,686,701...57,747,735
Ensembl chr18:55,416,413...55,483,083

G

Src homology 2 domain containing E

decreases expression

sulforaphane results in decreased expression of SHE mRNA

NCBI chr 2:177,559,636...177,585,485
Ensembl chr 2:175,262,442...175,286,669

G

sialic acid binding Ig-like lectin 10

increases expression

sulforaphane results in increased expression of SIGLEC10 mRNA

NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:93,817,335...93,825,931

G

sialic acid binding Ig-like lectin 5

decreases expression

sulforaphane results in decreased expression of SIGLEC6 mRNA

NCBI chr 1:102,904,705...102,913,281
Ensembl chr 1:93,768,319...93,776,694

G

signal-induced proliferation-associated 1 like 1

increases expression

sulforaphane results in increased expression of SIPA1L1 mRNA

NCBI chr 6:107,570,569...107,849,613
Ensembl chr 6:101,839,404...102,116,950

G

sirtuin 1

increases expression

sulforaphane results in increased expression of SIRT1 protein

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260

G

spindle and kinetochore associated complex subunit 2

decreases expression

sulforaphane results in decreased expression of SKA2 mRNA

NCBI chr10:72,418,707...72,436,721
Ensembl chr10:71,921,582...71,939,458

G

SKI-like proto-oncogene

increases expression

sulforaphane results in increased expression of SKIL mRNA

NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080

G

SLAM family member 6

decreases expression

sulforaphane results in decreased expression of SLAMF6 mRNA

NCBI chr13:86,916,956...86,937,697
Ensembl chr13:84,383,742...84,405,300

G

solute carrier family 10 member 1

decreases expression

sulforaphane results in decreased expression of SLC10A1 mRNA

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 10 member 6

decreases expression

sulforaphane results in decreased expression of SLC10A6 mRNA

NCBI chr14:6,385,348...6,407,532
Ensembl chr14:6,080,717...6,103,037

G

solute carrier family 12 member 3

decreases expression

sulforaphane results in decreased expression of SLC12A3 mRNA

NCBI chr19:10,636,594...10,690,008
Ensembl chr19:10,631,393...10,669,091

G

solute carrier family 12 member 7

increases expression

sulforaphane results in increased expression of SLC12A7 mRNA

NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 12, member 8

increases expression

sulforaphane results in increased expression of SLC12A8 mRNA

NCBI chr11:80,622,000...80,771,674
Ensembl chr11:67,116,877...67,266,834

G

solute carrier family 13 member 1

increases expression

sulforaphane results in increased expression of SLC13A1 mRNA

NCBI chr 4:53,534,763...53,612,704
Ensembl chr 4:52,569,375...52,647,099

G

solute carrier family 16, member 14

increases expression

sulforaphane results in increased expression of SLC16A14 mRNA

NCBI chr 9:93,558,144...93,585,396
Ensembl chr 9:86,112,894...86,137,318

G

solute carrier family 16, member 4

decreases expression

sulforaphane results in decreased expression of SLC16A4 mRNA

NCBI chr 2:197,593,738...197,621,569
Ensembl chr 2:194,911,236...194,933,117

G

solute carrier family 1 member 3

increases expression

sulforaphane results in increased expression of SLC1A3 mRNA

NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 1 member 5

increases expression

sulforaphane results in increased expression of SLC1A5 mRNA

NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 20 member 1

increases expression

sulforaphane results in increased expression of SLC20A1 mRNA

NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 22, member 23

increases expression

sulforaphane results in increased expression of SLC22A23 mRNA

NCBI chr17:30,749,445...30,915,139
Ensembl chr17:30,544,106...30,709,790

G

solute carrier family 22 member 8

affects expression

sulforaphane affects the expression of SLC22A8 protein

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:205,498,084...205,517,450

G

solute carrier family 25 member 29

decreases expression

sulforaphane results in decreased expression of SLC25A29 mRNA

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 25, member 51

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SLC25A51 mRNA

NCBI chr 5:64,445,610...64,459,172
Ensembl chr 5:59,649,744...59,663,581

G

solute carrier family 26 member 2

increases expression

sulforaphane results in increased expression of SLC26A2 mRNA

NCBI chr18:56,918,662...56,937,032
Ensembl chr18:54,652,951...54,666,626

G

solute carrier family 27 member 1

increases expression

sulforaphane results in increased expression of SLC27A1 mRNA

NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 27 member 2

increases expression

sulforaphane results in increased expression of SLC27A2 mRNA

NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 27 member 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SLC27A4 mRNA

NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943

G

solute carrier family 28 member 3

decreases expression

sulforaphane results in decreased expression of SLC28A3 mRNA

NCBI chr17:6,068,034...6,120,421
Ensembl chr17:6,062,549...6,114,038

G

solute carrier family 2 member 3

increases expression

sulforaphane results in increased expression of SLC2A3 mRNA

NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472

G

solute carrier family 2 member 4

increases expression

sulforaphane results in increased expression of SLC2A4 mRNA

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:54,666,015...54,671,565

G

solute carrier family 2 member 5

decreases expression

sulforaphane results in decreased expression of SLC2A5 mRNA

NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 35, member G2

increases expression

sulforaphane results in increased expression of SLC35G2 mRNA

NCBI chr 8:109,964,589...109,992,347
Ensembl chr 8:101,085,545...101,113,349

G

solute carrier family 37, member 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SLC37A3 mRNA

NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:68,081,939...68,153,568

G

solute carrier family 38, member 3

decreases expression

sulforaphane results in decreased expression of SLC38A3 mRNA

NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:108,323,894...108,339,988

G

solute carrier family 38, member 4

decreases expression

sulforaphane results in decreased expression of SLC38A4 mRNA

NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:128,144,807...128,202,995

G

solute carrier family 38, member 6

increases expression

sulforaphane results in increased expression of SLC38A6 mRNA

NCBI chr 6:97,723,526...97,814,394
Ensembl chr 6:91,987,672...92,049,935

G

solute carrier family 39 member 2

multiple interactions

sulforaphane promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]

NCBI chr15:27,063,699...27,066,349
Ensembl chr15:24,590,738...24,592,850

G

solute carrier family 3 member 2

decreases expression

sulforaphane results in decreased expression of SLC3A2 mRNA

NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 40 member 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [Busulfan results in decreased expression of SLC40A1 protein]; sulforaphane inhibits the reaction [Lipopolysaccharides results in decreased expression of SLC40A1 mRNA]
sulforaphane results in increased expression of SLC40A1 protein

PMID:21303654 PMID:32416107

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 43, member 3

decreases expression

sulforaphane results in decreased expression of SLC43A3 mRNA

NCBI chr 3:90,414,822...90,450,654
Ensembl chr 3:70,009,313...70,029,749

G

solute carrier family 44, member 4

increases expression

sulforaphane results in increased expression of SLC44A4 mRNA

NCBI chr20:3,907,737...3,923,911
Ensembl chr20:3,903,099...3,919,215

G

solute carrier family 47 member 1

increases expression

sulforaphane results in increased expression of SLC47A1 mRNA

NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,034,122...46,087,637

G

solute carrier family 48 member 1

increases expression

sulforaphane results in increased expression of SLC48A1 mRNA

NCBI chr 7:130,794,233...130,802,119
Ensembl chr 7:128,915,195...128,923,024

G

solute carrier family 4 member 3

increases expression

sulforaphane results in increased expression of SLC4A3 mRNA

NCBI chr 9:84,484,749...84,497,746
Ensembl chr 9:77,037,016...77,049,105

G

solute carrier family 4 member 8

decreases expression

sulforaphane results in decreased expression of SLC4A8 mRNA

NCBI chr 7:133,742,830...133,818,056
Ensembl chr 7:131,864,102...131,931,051

G

solute carrier family 51 member A

decreases expression

sulforaphane results in decreased expression of SLC51A mRNA

NCBI chr11:81,804,141...81,818,539
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 6 member 6

increases expression

sulforaphane results in increased expression of SLC6A6 mRNA

NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:124,195,218...124,268,875

G

solute carrier family 7 member 11

increases expression

sulforaphane results in increased expression of SLC7A11 mRNA

PMID:31838189 PMID:34767876

NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536

G

solute carrier organic anion transporter family, member 2a1

decreases expression

sulforaphane results in decreased expression of SLCO2A1 mRNA

NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:103,588,916...103,672,546

G

solute carrier organic anion transporter family, member 3a1

decreases expression

sulforaphane results in decreased expression of SLCO3A1 mRNA

NCBI chr 1:137,516,037...137,797,836
Ensembl chr 1:128,106,228...128,387,925

G

solute carrier organic anion transporter family, member 4C1

increases expression

sulforaphane results in increased expression of SLCO4C1 mRNA

NCBI chr 9:104,624,802...104,676,462
Ensembl chr 9:97,178,861...97,229,715

G

SMC5-SMC6 complex localization factor 1

decreases expression

sulforaphane results in decreased expression of SLF1 mRNA

NCBI chr 2:8,498,776...8,606,251
Ensembl chr 2:6,767,015...6,867,149

G

secreted Ly6/Plaur domain containing 1

increases expression

sulforaphane results in increased expression of SLURP1 mRNA

NCBI chr 7:108,500,933...108,502,349
Ensembl chr 7:106,611,949...106,613,365

G

SPARC related modular calcium binding 1

increases expression

sulforaphane results in increased expression of SMOC1 mRNA

NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:100,701,346...100,862,699

G

spermine oxidase

increases expression

sulforaphane results in increased expression of SMOX mRNA

NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:118,731,900...118,765,710
Ensembl chr X:118,731,900...118,765,710

G

sphingomyelin phosphodiesterase, acid-like 3B

decreases expression

sulforaphane results in decreased expression of SMPDL3B mRNA

NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:144,944,636...144,966,720

G

small muscle protein, X-linked

increases expression

sulforaphane results in increased expression of SMPX mRNA

NCBI chr X:41,049,354...41,107,323
Ensembl chr X:37,234,294...37,276,708

G

SET and MYND domain containing 1

increases expression

sulforaphane results in increased expression of SMYD1 mRNA

NCBI chr 4:104,757,281...104,811,307
Ensembl chr 4:103,200,322...103,311,766

G

snail family transcriptional repressor 1

multiple interactions

sulforaphane inhibits the reaction [Paraquat results in increased expression of SNAI1 protein]

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

snail family transcriptional repressor 2

decreases expression

sulforaphane results in decreased expression of SNAI2 mRNA

NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200

G

synaptosome associated protein 25

decreases expression

sulforaphane results in decreased expression of SNAP25 mRNA

NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:124,041,898...124,123,760

G

small nuclear RNA activating complex, polypeptide 3

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SNAPC3 mRNA
sulforaphane results in decreased expression of SNAPC3 mRNA

NCBI chr 5:102,863,867...102,890,573
Ensembl chr 5:97,817,947...97,844,650

G

SNAP-associated protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SNAPIN mRNA

NCBI chr 2:178,269,157...178,271,746
Ensembl chr 2:175,971,257...175,974,231

G

synuclein, gamma

decreases expression

sulforaphane results in decreased expression of SNCG mRNA

NCBI chr16:9,706,765...9,712,072
Ensembl chr16:9,700,514...9,705,368

G

staphylococcal nuclease and tudor domain containing 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SND1 mRNA

NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:57,095,208...57,530,843

G

small nucleolar RNA host gene 11

decreases expression

sulforaphane results in decreased expression of SNHG11 mRNA

NCBI chr 3:167,451,272...167,456,945

G

small nucleolar RNA, H/ACA box 3A

increases expression

sulforaphane results in increased expression of SNORA3A mRNA

NCBI chr 7:125,820,534...125,820,664
Ensembl chr 1:163,540,664...163,540,793

G

SNF related kinase

decreases expression

sulforaphane results in decreased expression of SNRK mRNA

NCBI chr 8:130,657,204...130,711,461
Ensembl chr 8:121,793,302...121,832,323

G

small nuclear ribonucleoprotein U11/U12 subunit 48

decreases expression

sulforaphane results in decreased expression of SNRNP48 mRNA

NCBI chr17:26,801,818...26,821,605
Ensembl chr17:26,596,275...26,616,040

G

sorting nexin 25

decreases expression

sulforaphane results in decreased expression of SNX25 mRNA

NCBI chr16:52,867,102...52,971,028
Ensembl chr16:46,125,804...46,238,440

G

superoxide dismutase 1

increases expression
multiple interactions

sulforaphane results in increased expression of SOD1 protein
sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]

PMID:24707343 PMID:25111660

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

increases expression
multiple interactions

sulforaphane results in increased expression of SOD2 mRNA; sulforaphane results in increased expression of SOD2 protein
sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

sorbin and SH3 domain containing 2

increases expression
decreases expression

sulforaphane results in increased expression of SORBS2 mRNA
sulforaphane results in decreased expression of SORBS2 mRNA

PMID:30529165 PMID:31838189

NCBI chr16:53,167,795...53,481,300
Ensembl chr16:46,435,237...46,626,514

G

sortilin-related VPS10 domain containing receptor 2

decreases expression

sulforaphane results in decreased expression of SORCS2 mRNA

NCBI chr14:78,592,290...78,960,582
Ensembl chr14:74,371,415...74,735,943

G

sortilin related receptor 1

decreases expression

sulforaphane results in decreased expression of SORL1 mRNA

NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513

G

SRY-box transcription factor 15

decreases expression

sulforaphane results in decreased expression of SOX15 mRNA

NCBI chr10:54,871,793...54,873,497
Ensembl chr10:54,372,403...54,376,591

G

SRY-box transcription factor 4

decreases expression

sulforaphane results in decreased expression of SOX4 mRNA

NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,667,537...35,673,665

G

SRY-box transcription factor 9

increases expression

sulforaphane results in increased expression of SOX9 mRNA; sulforaphane results in increased expression of SOX9 protein

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994

G

sperm acrosome associated 6

decreases expression

sulforaphane results in decreased expression of SPACA6 mRNA

NCBI chr 1:67,345,996...67,365,210
Ensembl chr 1:58,677,797...58,688,562

G

spermatogenesis associated 17

increases expression

sulforaphane results in increased expression of SPATA17 mRNA

NCBI chr13:101,137,415...101,316,221
Ensembl chr13:98,605,986...98,784,929

G

spermatogenesis associated 24

increases expression

sulforaphane results in increased expression of SPATA24 mRNA

NCBI chr18:27,523,133...27,531,375
Ensembl chr18:27,248,609...27,257,124

G

serine peptidase inhibitor Kazal type 13

decreases expression

sulforaphane results in decreased expression of SPINK13 mRNA

NCBI chr18:58,335,146...58,476,569
Ensembl chr18:56,064,839...56,206,257

G

serine peptidase inhibitor, Kunitz type 1

decreases expression

sulforaphane results in decreased expression of SPINT1 mRNA

NCBI chr 3:126,685,017...126,697,957
Ensembl chr 3:106,231,444...106,244,119

G

spondin 2

decreases expression

sulforaphane results in decreased expression of SPON2 mRNA

NCBI chr14:81,713,070...81,742,510
Ensembl chr14:77,511,901...77,517,996

G

secreted phosphoprotein 1

increases expression

sulforaphane results in increased expression of SPP1 mRNA

PMID:26833863 PMID:27562236

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162

G

sprouty-related, EVH1 domain containing 1

increases expression

sulforaphane results in increased expression of SPRED1 mRNA

NCBI chr 3:124,437,230...124,504,358
Ensembl chr 3:103,983,072...104,049,718

G

sprouty-related, EVH1 domain containing 2

increases expression

sulforaphane results in increased expression of SPRED2 mRNA

NCBI chr14:98,350,577...98,452,143
Ensembl chr14:94,148,837...94,249,162

G

sprouty-related, EVH1 domain containing 3

increases expression

sulforaphane results in increased expression of SPRED3 mRNA

NCBI chr 1:93,586,259...93,597,692
Ensembl chr 1:84,459,314...84,470,249

G

small proline-rich protein 1A

increases expression

sulforaphane results in increased expression of SPRR1A mRNA

NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:178,055,096...178,057,063

G

sprouty RTK signaling antagonist 4

increases expression

sulforaphane results in increased expression of SPRY4 mRNA

NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,436,443...30,453,004

G

splA/ryanodine receptor domain and SOCS box containing 1

increases expression

sulforaphane results in increased expression of SPSB1 mRNA

NCBI chr 5:165,641,255...165,701,482
Ensembl chr 5:160,358,308...160,418,468

G

serine palmitoyltransferase, long chain base subunit 3

decreases expression

sulforaphane results in decreased expression of SPTLC3 mRNA

NCBI chr 3:147,301,570...147,431,696
Ensembl chr 3:126,847,878...126,978,010

G

sequestosome 1

multiple interactions
increases expression
decreases expression

sulforaphane inhibits the reaction [sodium arsenite affects the localization of SQSTM1 protein]
sulforaphane results in increased expression of SQSTM1 mRNA; sulforaphane results in increased expression of SQSTM1 protein
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of SQSTM1 protein]
sulforaphane results in decreased expression of SQSTM1 mRNA

PMID:23589329 PMID:29950142 PMID:31838189 PMID:33894213 PMID:35724838

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673

G

steroid 5 alpha-reductase 3

decreases expression

sulforaphane results in decreased expression of SRD5A3 mRNA

NCBI chr14:32,400,603...32,414,987
Ensembl chr14:32,046,408...32,060,747

G

sterol regulatory element binding transcription factor 1

multiple interactions
decreases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of SREBF1 mRNA
sulforaphane inhibits the reaction [bisphenol A results in increased expression of SREBF1 mRNA]; sulforaphane promotes the reaction [NFE2L2 protein results in increased expression of SREBF1 mRNA]
sulforaphane results in decreased expression of SREBF1 mRNA

PMID:25450479 PMID:28796629 PMID:31838189 PMID:34767876 PMID:36670177

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

SLIT-ROBO Rho GTPase activating protein 3

decreases expression

sulforaphane results in decreased expression of SRGAP3 mRNA

NCBI chr 4:147,391,082...147,626,407
Ensembl chr 4:145,840,078...146,070,575

G

serglycin

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SRGN mRNA
sulforaphane results in increased expression of SRGN mRNA

PMID:30529165 PMID:31838189

NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,442,813...30,457,406

G

sarcalumenin

increases expression

sulforaphane results in increased expression of SRL mRNA

NCBI chr10:11,540,365...11,584,506
Ensembl chr10:11,034,035...11,078,101

G

sulfiredoxin 1

increases expression
decreases expression

sulforaphane results in increased expression of SRXN1 mRNA; sulforaphane results in increased expression of SRXN1 protein
sulforaphane results in decreased expression of SRXN1 mRNA

PMID:26833863 PMID:31838189 PMID:35724838

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448

G

single-stranded DNA binding protein 2

decreases expression

sulforaphane results in decreased expression of SSBP2 mRNA

NCBI chr 2:24,385,494...24,673,768
Ensembl chr 2:22,651,258...22,933,696

G

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

decreases expression

sulforaphane results in decreased expression of ST6GALNAC2 mRNA

NCBI chr10:102,409,048...102,427,299
Ensembl chr10:101,909,971...101,915,008
Ensembl chr10:101,909,971...101,915,008

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

increases expression

sulforaphane results in increased expression of ST8SIA6 mRNA

NCBI chr17:81,649,866...81,847,970
Ensembl chr17:76,745,224...76,884,299

G

stabilin 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of STAB1 mRNA

NCBI chr16:6,336,871...6,367,374
Ensembl chr16:6,330,444...6,360,923

G

SH3 and cysteine rich domain 2

decreases expression

sulforaphane results in decreased expression of STAC2 mRNA

NCBI chr10:83,528,741...83,544,583
Ensembl chr10:83,032,417...83,048,260

G

STAM binding protein-like 1

increases expression

sulforaphane results in increased expression of STAMBPL1 mRNA

NCBI chr 1:241,095,695...241,158,225
Ensembl chr 1:231,699,995...231,745,032

G

StAR-related lipid transfer domain containing 10

decreases expression

sulforaphane results in decreased expression of STARD10 mRNA

NCBI chr 1:165,130,408...165,159,134
Ensembl chr 1:155,718,389...155,747,094

G

StAR-related lipid transfer domain containing 13

decreases expression

sulforaphane results in decreased expression of STARD13 mRNA

NCBI chr12:5,401,878...5,797,937
Ensembl chr12:566,310...959,421

G

signal transducer and activator of transcription 3

decreases expression

sulforaphane results in decreased expression of STAT3 mRNA

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057

G

STEAP family member 1

increases expression

sulforaphane results in increased expression of STEAP1 mRNA

NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:28,276,909...28,287,479

G

STEAP4 metalloreductase

increases expression
decreases expression

sulforaphane results in increased expression of STEAP4 mRNA
sulforaphane results in decreased expression of STEAP4 mRNA

PMID:30529165 PMID:31838189

NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:26,054,671...26,099,859

G

stonin 1

decreases expression

sulforaphane results in decreased expression of STON1 mRNA

NCBI chr 6:11,596,726...11,646,098
Ensembl chr 6:5,843,185...5,892,449

G

storkhead box 2

decreases expression

sulforaphane results in decreased expression of STOX2 mRNA

NCBI chr16:51,580,855...51,819,909
Ensembl chr16:44,848,078...45,085,105

G

striatin interacting protein 2

increases expression

sulforaphane results in increased expression of STRIP2 mRNA

NCBI chr 4:59,503,478...59,545,745
Ensembl chr 4:58,536,055...58,578,291

G

syntaxin 12

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of STX12 mRNA

NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:145,063,587...145,092,377

G

succinate receptor 1

increases expression

sulforaphane results in increased expression of SUCNR1 mRNA

NCBI chr 2:146,368,858...146,380,360
Ensembl chr 2:144,219,122...144,230,034

G

sulfatase 2

increases expression

sulforaphane results in increased expression of SULF2 mRNA

NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:154,822,085...154,904,415

G

SPT20 homolog, SAGA complex component

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SUPT20 mRNA

NCBI chr 2:141,047,479...141,080,656
Ensembl chr 2:138,897,416...138,930,495

G

synaptic vesicle glycoprotein 2b

decreases expression

sulforaphane results in decreased expression of SV2B mRNA

NCBI chr 1:138,388,268...138,562,635
Ensembl chr 1:128,978,473...129,152,479

G

SWT1 RNA endoribonuclease homolog

increases expression

sulforaphane results in increased expression of SWT1 mRNA

NCBI chr13:66,002,477...66,059,962
Ensembl chr13:63,452,496...63,509,980

G

synaptogyrin 1

decreases expression

sulforaphane results in decreased expression of SYNGR1 mRNA

NCBI chr 7:113,516,246...113,542,918
Ensembl chr 7:111,635,918...111,659,341

G

synaptogyrin 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of SYNGR2 mRNA

NCBI chr10:103,528,599...103,533,167
Ensembl chr10:103,029,917...103,034,473

G

synaptogyrin 3

decreases expression

sulforaphane results in decreased expression of SYNGR3 mRNA

NCBI chr10:14,215,088...14,219,844
Ensembl chr10:13,704,998...13,715,669

G

synemin

decreases expression

sulforaphane results in decreased expression of SYNM mRNA

NCBI chr 1:130,743,891...130,774,254
Ensembl chr 1:121,333,720...121,363,652

G

synaptopodin

decreases expression
increases methylation

sulforaphane results in decreased expression of SYNPO mRNA
sulforaphane results in increased methylation of SYNPO gene

NCBI chr18:56,326,369...56,347,359
Ensembl chr18:54,026,152...54,102,126

G

synaptotagmin 12

decreases expression

sulforaphane results in decreased expression of SYT12 mRNA

NCBI chr 1:211,158,745...211,189,780
Ensembl chr 1:201,730,371...201,759,609

G

synaptotagmin 7

decreases expression

sulforaphane results in decreased expression of SYT7 mRNA

NCBI chr 1:216,456,148...216,518,718
Ensembl chr 1:207,031,592...207,089,026

G

SZT2 subunit of KICSTOR complex

decreases expression

sulforaphane results in decreased expression of SZT2 mRNA

NCBI chr 5:137,182,648...137,229,349
Ensembl chr 5:131,897,275...131,943,904

G

tumor-associated calcium signal transducer 2

increases expression

sulforaphane results in increased expression of TACSTD2 mRNA

NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:96,707,951...96,709,650

G

transgelin 2

decreases expression

sulforaphane results in decreased expression of TAGLN2 mRNA

NCBI chr13:87,499,350...87,506,328
Ensembl chr13:84,967,009...84,973,972

G

transaldolase 1

increases expression

sulforaphane results in increased expression of TALDO1 mRNA

NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:196,493,589...196,503,974

G

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

decreases expression

sulforaphane results in decreased expression of TANC2 mRNA

NCBI chr10:91,052,860...91,373,291
Ensembl chr10:90,553,002...90,868,756

G

transporter 1, ATP binding cassette subfamily B member

increases expression

sulforaphane results in increased expression of TAP1 mRNA

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,656,263...4,666,901

G

TLR adaptor interacting with endolysosomal SLC15A4

decreases expression

sulforaphane results in decreased expression of TASL mRNA

NCBI chr X:54,354,755...54,373,930
Ensembl chr X:50,361,248...50,423,269

G

TBC1 domain family, member 30

decreases expression

sulforaphane results in decreased expression of TBC1D30 mRNA

NCBI chr 7:58,665,054...58,754,427
Ensembl chr 7:56,782,165...56,870,515

G

tubulin folding cofactor B

affects binding
decreases expression

TBCB protein binds to sulforaphane
sulforaphane results in decreased expression of TBCB mRNA

PMID:21838287 PMID:31838189

NCBI chr 1:94,605,100...94,610,949
Ensembl chr 1:85,477,640...85,483,488

G

transducin (beta)-like 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of TBL3 mRNA

NCBI chr10:14,230,660...14,235,873
Ensembl chr10:13,726,129...13,731,372

G

T-box transcription factor 1

decreases expression

sulforaphane results in decreased expression of TBX1 mRNA

NCBI chr11:95,913,610...95,923,392
Ensembl chr11:82,409,275...82,418,380

G

T-box transcription factor 15

decreases methylation

sulforaphane results in decreased methylation of TBX15 gene

NCBI chr 2:189,265,373...189,376,466
Ensembl chr 2:186,576,676...186,687,663

G

thromboxane A2 receptor

decreases expression

sulforaphane results in decreased expression of TBXA2R mRNA

NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:8,383,378...8,388,176

G

transcription elongation factor A like 3

decreases expression

sulforaphane results in decreased expression of TCEAL3 mRNA

NCBI chr  X:104,802,966...104,804,926
Ensembl chr  X:100,010,690...100,012,654
Ensembl chr  X:100,010,690...100,012,654

G

transcription factor 19

decreases expression

sulforaphane results in decreased expression of TCF19 mRNA

NCBI chr20:3,223,464...3,227,569
Ensembl chr20:3,218,693...3,223,271

G

transcription factor 21

decreases expression

sulforaphane results in decreased expression of TCF21 mRNA

NCBI chr 1:24,520,499...24,523,358
Ensembl chr 1:22,701,353...22,704,202

G

transcription factor 7 like 1

decreases expression

sulforaphane results in decreased expression of TCF7L1 mRNA

NCBI chr 4:106,238,892...106,404,012
Ensembl chr 4:104,680,739...104,845,287

G

transcriptional and immune response regulator

decreases expression

sulforaphane results in decreased expression of TCIM mRNA

NCBI chr16:74,298,344...74,299,637
Ensembl chr16:67,593,410...67,597,581

G

t-complex 11 like 1

decreases expression

sulforaphane results in decreased expression of TCP11L1 mRNA

NCBI chr 3:111,478,787...111,547,553
Ensembl chr 3:90,998,270...91,092,006

G

TEA domain transcription factor 2

decreases expression

sulforaphane results in decreased expression of TEAD2 mRNA

NCBI chr 1:104,838,795...104,855,635
Ensembl chr 1:95,703,005...95,719,186

G

trans-2,3-enoyl-CoA reductase-like

increases expression

sulforaphane results in increased expression of TECRL mRNA

NCBI chr14:25,086,930...25,159,957
Ensembl chr14:24,732,241...24,805,272

G

tektin 4

increases expression

sulforaphane results in increased expression of TEKT4 mRNA

NCBI chr10:14,992,284...14,997,460
Ensembl chr10:14,487,760...14,492,936

G

terminal nucleotidyltransferase 5B

decreases expression

sulforaphane results in decreased expression of TENT5B mRNA

NCBI chr 5:150,979,238...150,986,548
Ensembl chr 5:145,695,362...145,706,073
Ensembl chr11:145,695,362...145,706,073

G

telomerase reverse transcriptase

decreases expression

sulforaphane results in decreased expression of TERT mRNA

NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561

G

testis expressed 11

decreases expression

sulforaphane results in decreased expression of TEX11 mRNA

NCBI chr X:69,973,012...70,236,544
Ensembl chr X:65,932,988...66,196,187

G

transcription factor A, mitochondrial

increases expression

sulforaphane results in increased expression of TFAM protein

NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292

G

transcription factor binding to IGHM enhancer 3

increases expression

sulforaphane results in increased expression of TFE3 mRNA

NCBI chr X:17,401,466...17,414,829
Ensembl chr X:14,729,550...14,742,571

G

transcription factor EC

decreases expression

sulforaphane results in decreased expression of TFEC mRNA

NCBI chr 4:46,072,093...46,146,200
Ensembl chr 4:45,107,641...45,180,236

G

trefoil factor 2

increases expression

sulforaphane results in increased expression of TFF2 mRNA

NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,215,761...9,219,619

G

transferrin receptor

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta 1

multiple interactions

sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]

PMID:24707343 PMID:24967692 PMID:29353218

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor, beta 3

decreases expression

sulforaphane results in decreased expression of TGFB3 mRNA

NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:105,704,236...105,726,564

G

transforming growth factor, beta receptor 1

affects methylation

sulforaphane affects the methylation of TGFBR1 promoter

NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:61,653,233...61,710,777

G

transglutaminase 1

decreases expression

sulforaphane results in decreased expression of TGM1 mRNA

NCBI chr15:33,160,985...33,175,632
Ensembl chr15:29,191,041...29,204,523

G

tyrosine hydroxylase

multiple interactions

sulforaphane inhibits the reaction [Oxidopamine results in decreased expression of TH protein]

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767

G

THAP domain containing 1

increases methylation

sulforaphane results in increased methylation of THAP1 gene

NCBI chr16:72,608,096...72,612,690
Ensembl chr16:65,904,230...65,909,942

G

thymocyte selection associated family member 2

increases expression

sulforaphane results in increased expression of THEMIS2 mRNA

NCBI chr 5:150,275,094...150,290,343
Ensembl chr 5:144,991,112...145,006,400

G

thyroid hormone responsive

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of THRSP mRNA
sulforaphane results in increased expression of THRSP mRNA

PMID:25450479 PMID:30529165

NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:151,723,086...151,728,075

G

TIMP metallopeptidase inhibitor 1

increases expression

sulforaphane results in increased expression of TIMP1 mRNA

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664

G

TIMP metallopeptidase inhibitor 2

increases expression

sulforaphane results in increased expression of TIMP2 mRNA

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611

G

TIMP metallopeptidase inhibitor 4

increases expression

sulforaphane results in increased expression of TIMP4 mRNA

PMID:30529165 PMID:31838189

NCBI chr 4:149,978,667...149,985,350
Ensembl chr 4:148,304,490...148,312,558

G

tubulointerstitial nephritis antigen

decreases expression
multiple interactions

sulforaphane results in decreased expression of TINAG mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TINAG mRNA

NCBI chr 8:86,680,441...86,765,485
Ensembl chr 8:77,800,032...77,885,077

G

tight junction protein 3

decreases expression

sulforaphane results in decreased expression of TJP3 mRNA

NCBI chr 7:9,078,757...9,097,003
Ensembl chr 7:8,432,811...8,446,279

G

TLE family member 6, subcortical maternal complex member

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TLE6 mRNA

NCBI chr 7:8,757,846...8,769,405
Ensembl chr 7:8,107,207...8,118,639

G

tolloid-like 1

decreases expression

sulforaphane results in decreased expression of TLL1 mRNA

NCBI chr16:30,275,492...30,476,673
Ensembl chr16:25,509,146...25,709,543

G

toll-like receptor 4

increases expression
multiple interactions

sulforaphane results in increased expression of TLR4 mRNA
sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of TLR4 protein]

PMID:26833863 PMID:31838189 PMID:33007382

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628

G

toll-like receptor 6

increases expression

sulforaphane results in increased expression of TLR6 mRNA

PMID:26833863 PMID:31838189

NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685

G

transmembrane 6 superfamily member 1

increases expression

sulforaphane results in increased expression of TM6SF1 mRNA

NCBI chr 1:145,209,052...145,237,725
Ensembl chr 1:135,786,381...135,828,443

G

transmembrane BAX inhibitor motif containing 1

increases expression

sulforaphane results in increased expression of TMBIM1 mRNA

NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:75,871,835...75,889,069

G

transmembrane channel-like 5

decreases expression

sulforaphane results in decreased expression of TMC5 mRNA

NCBI chr 1:182,349,102...182,433,679
Ensembl chr 1:172,914,457...172,999,474

G

transmembrane and coiled-coil domain family 2

decreases expression

sulforaphane results in decreased expression of TMCC2 mRNA

NCBI chr13:46,346,177...46,383,862
Ensembl chr13:43,794,029...43,831,716

G

transmembrane protein with EGF-like and two follistatin-like domains 2

decreases expression

sulforaphane results in decreased expression of TMEFF2 mRNA

NCBI chr 9:57,937,873...58,225,372
Ensembl chr 9:50,436,079...50,733,475

G

transmembrane protein 100

decreases expression

sulforaphane results in decreased expression of TMEM100 mRNA

NCBI chr10:75,351,891...75,357,748
Ensembl chr10:74,854,468...74,862,941

G

transmembrane protein 107

increases expression
decreases expression

sulforaphane results in increased expression of TMEM107 mRNA
sulforaphane results in decreased expression of TMEM107 mRNA

PMID:30529165 PMID:31838189

NCBI chr10:54,268,218...54,273,520
Ensembl chr10:53,771,784...53,774,676

G

transmembrane protein 116

increases expression

sulforaphane results in increased expression of TMEM116 mRNA

NCBI chr12:40,681,346...40,750,106
Ensembl chr12:35,041,572...35,089,430

G

transmembrane protein 121

decreases expression

sulforaphane results in decreased expression of TMEM121 mRNA

NCBI chr 6:132,262,182...132,265,797
Ensembl chr 6:132,262,176...132,265,914

G

transmembrane protein 156

increases expression

sulforaphane results in increased expression of TMEM156 mRNA

NCBI chr14:43,568,131...43,606,109
Ensembl chr14:43,223,381...43,252,449

G

transmembrane protein 160

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of TMEM160 mRNA

NCBI chr 1:86,292,582...86,295,290
Ensembl chr 1:77,164,448...77,167,156

G

transmembrane protein 178B

decreases expression

sulforaphane results in decreased expression of TMEM178B mRNA

NCBI chr 4:69,626,188...70,002,400
Ensembl chr 4:68,657,343...69,035,690

G

transmembrane protein 192

increases expression

sulforaphane results in increased expression of TMEM192 mRNA

NCBI chr16:24,740,166...24,760,994
Ensembl chr16:24,740,124...24,761,021

G

transmembrane protein 232

increases expression

sulforaphane results in increased expression of TMEM232 mRNA

NCBI chr 9:112,334,569...112,562,627
Ensembl chr 9:104,887,669...105,143,027

G

transmembrane protein 243

decreases expression

sulforaphane results in decreased expression of TMEM243 mRNA

NCBI chr 4:25,905,740...25,923,588
Ensembl chr 4:24,950,791...24,968,642

G

transmembrane protein 25

decreases expression

sulforaphane results in decreased expression of TMEM25 mRNA

NCBI chr 8:54,003,907...54,009,469
Ensembl chr 8:45,107,121...45,116,389

G

transmembrane protein 37

increases expression

sulforaphane results in increased expression of TMEM37 mRNA

NCBI chr13:33,737,096...33,743,602
Ensembl chr13:31,171,355...31,191,077

G

transmembrane protein 45b

increases expression

sulforaphane results in increased expression of TMEM45B mRNA

NCBI chr 8:38,123,423...38,168,599
Ensembl chr 8:29,865,278...29,910,453

G

transmembrane protein 71

increases expression

sulforaphane results in increased expression of TMEM71 mRNA

NCBI chr 7:100,166,038...100,212,234
Ensembl chr 7:98,276,975...98,315,858

G

transmembrane protein 80

decreases expression

sulforaphane results in decreased expression of TMEM80 mRNA

NCBI chr 1:205,865,564...205,873,933
Ensembl chr 1:196,436,003...196,444,367
Ensembl chr 1:196,436,003...196,444,367

G

transmembrane protein 87B

increases expression

sulforaphane results in increased expression of TMEM87B mRNA

NCBI chr 3:136,515,155...136,550,644
Ensembl chr 3:116,062,204...116,097,367

G

TMEM9 domain family, member B

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of TMEM9B mRNA

NCBI chr 1:173,199,225...173,218,674
Ensembl chr 1:163,764,433...163,783,278

G

tropomodulin 1

decreases expression

sulforaphane results in decreased expression of TMOD1 mRNA

NCBI chr 5:65,112,062...65,189,563
Ensembl chr 5:60,338,512...60,393,956

G

tropomodulin 2

increases expression

sulforaphane results in increased expression of TMOD2 mRNA

NCBI chr 8:85,197,222...85,250,627
Ensembl chr 8:76,325,667...76,365,720

G

transmembrane serine protease 3

decreases expression

sulforaphane results in decreased expression of TMPRSS3 mRNA

NCBI chr20:9,253,497...9,275,167
Ensembl chr20:9,254,109...9,274,363

G

thiol methyltransferase 1A

decreases expression

sulforaphane results in decreased expression of TMT1A mRNA

NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:131,451,641...131,460,154

G

tenascin C

decreases expression

sulforaphane results in decreased expression of TNC mRNA

NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:77,375,851...77,460,624

G

tumor necrosis factor

multiple interactions
increases expression
decreases expression

NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]; sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF protein]; sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of TNF mRNA]
sulforaphane results in increased expression of TNF mRNA
sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of TNF protein]; sulforaphane inhibits the reaction [TNF protein affects the localization of NFKBIA protein]; sulforaphane inhibits the reaction [TNF protein affects the localization of RELA protein]; sulforaphane inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; sulforaphane inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TNF mRNA]; tin protoporphyrin IX inhibits the reaction [sulforaphane inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of TNF protein]]
sulforaphane metabolite results in decreased expression of TNF mRNA; sulforaphane results in decreased expression of TNF mRNA

PMID:21684301 PMID:24707343 PMID:26833863 PMID:29353218 PMID:30965051 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 2

increases expression

sulforaphane results in increased expression of TNFAIP2 mRNA

NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:130,476,889...130,489,914

G

TNF alpha induced protein 3

decreases expression
multiple interactions
increases expression

sulforaphane results in decreased expression of TNFAIP3 mRNA
sulforaphane inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]; sulforaphane inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]
sulforaphane results in increased expression of TNFAIP3 mRNA; sulforaphane results in increased expression of TNFAIP3 protein

PMID:31838189 PMID:35724838

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

G

TNF receptor superfamily member 10b

increases expression

sulforaphane results in increased expression of TNFRSF10A mRNA

NCBI chr15:51,249,883...51,278,091
Ensembl chr15:44,840,386...44,867,467

G

TNF receptor superfamily member 12A

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of TNFRSF12A mRNA

NCBI chr10:13,211,670...13,213,666
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 21

increases expression

sulforaphane results in increased expression of TNFRSF21 mRNA

NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085

G

TNF receptor superfamily member 9

increases expression

sulforaphane results in increased expression of TNFRSF9 mRNA

NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:161,381,662...161,408,000

G

TNF superfamily member 10

increases activity
multiple interactions

sulforaphane results in increased activity of TNFSF10 protein
[sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP3 protein; [sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP8 protein; [sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP9 protein; [sulforaphane co-treated with TNFSF10 protein] results in increased cleavage of BID protein; [sulforaphane co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; [sulforaphane co-treated with TNFSF10 protein] results in increased expression of TNFRSF10B protein

NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 14

increases expression

sulforaphane results in increased expression of TNFSF14 mRNA

NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,069,104...2,073,216

G

troponin C1, slow skeletal and cardiac type

increases expression

sulforaphane results in increased expression of TNNC1 mRNA

NCBI chr16:6,408,607...6,412,070
Ensembl chr16:6,402,171...6,405,634

G

troponin I3, cardiac type

increases expression
multiple interactions

sulforaphane results in increased expression of TNNI3 mRNA
sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TNNI3 protein]

PMID:30529165 PMID:37906532

NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:69,299,900...69,303,580

G

troponin T2, cardiac type

increases expression
decreases expression

sulforaphane results in increased expression of TNNT2 mRNA
sulforaphane results in decreased expression of TNNT2 mRNA

PMID:30529165 PMID:31838189

NCBI chr13:49,819,123...49,837,125
Ensembl chr13:47,267,204...47,285,388

G

TOP6B like initiator of meiotic double strand breaks

decreases expression

sulforaphane results in decreased expression of TOP6BL mRNA

NCBI chr 1:211,331,973...211,419,015

G

thymocyte selection-associated high mobility group box

decreases expression

sulforaphane results in decreased expression of TOX mRNA

NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:19,874,467...20,171,272

G

tumor protein p53

multiple interactions
decreases expression

sulforaphane inhibits the reaction [TRP53 gene mutant form results in decreased susceptibility to Doxorubicin]; sulforaphane inhibits the reaction [TRP53 gene polymorphism results in decreased susceptibility to Doxorubicin]
sulforaphane results in decreased expression of TP53 protein
sulforaphane inhibits the reaction [triptolide results in increased expression of TP53 protein]

PMID:16843502 PMID:17404018 PMID:27878984 PMID:36990132

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 inducible protein 11

decreases expression

sulforaphane results in decreased expression of TP53I11 mRNA

NCBI chr 3:99,600,213...99,615,462
Ensembl chr 3:79,144,895...79,160,050

G

tumor protein p73

increases expression

sulforaphane results in increased expression of TP73 protein

NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128

G

tropomyosin 1

affects binding
increases expression

TPM1 protein binds to sulforaphane
sulforaphane results in increased expression of TPM1 mRNA

PMID:21838287 PMID:30529165

NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:67,635,479...67,662,802

G

tropomyosin 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of TPM4 mRNA

NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,683,195...17,705,984

G

TNF receptor-associated factor 1

decreases expression

sulforaphane results in decreased expression of TRAF1 mRNA

NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:18,222,054...18,241,807

G

TRAF type zinc finger domain containing 1

decreases expression

sulforaphane results in decreased expression of TRAFD1 mRNA

NCBI chr12:40,826,251...40,840,169
Ensembl chr12:35,165,606...35,179,525

G

triggering receptor expressed on myeloid cells 1

increases expression

sulforaphane results in increased expression of TREM1 mRNA

NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:12,763,819...12,779,203

G

triggering receptor expressed on myeloid cells-like 2

increases expression

sulforaphane results in increased expression of TREML2 mRNA

NCBI chr 9:12,694,453...12,705,379
Ensembl chr 9:12,694,697...12,705,324

G

tribbles pseudokinase 2

decreases expression

sulforaphane results in decreased expression of TRIB2 mRNA

NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:38,545,975...38,569,370

G

tribbles pseudokinase 3

decreases expression

sulforaphane results in decreased expression of TRIB3 mRNA

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif-containing 16

increases expression

sulforaphane results in increased expression of TRIM16 mRNA

NCBI chr10:47,985,235...48,008,242
Ensembl chr10:47,486,297...47,551,907

G

tripartite motif-containing 29

decreases expression

sulforaphane results in decreased expression of TRIM29 mRNA

NCBI chr 8:52,579,175...52,603,919
Ensembl chr 8:43,682,221...43,706,992

G

tripartite motif-containing 5

decreases expression

sulforaphane results in decreased expression of TRIM5 mRNA

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:158,720,410...158,814,012

G

tripartite motif-containing 54

increases expression

sulforaphane results in increased expression of TRIM54 mRNA

NCBI chr 6:30,959,306...30,978,475
Ensembl chr 6:25,239,340...25,258,511

G

thyroid hormone receptor interactor 13

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of TRIP13 mRNA

NCBI chr 1:31,185,700...31,230,638
Ensembl chr 1:29,357,130...29,402,074

G

tRNA methyltransferase 13 homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of TRMT13 mRNA

NCBI chr 2:207,217,399...207,232,467
Ensembl chr 2:204,533,632...204,546,843

G

transient receptor potential cation channel, subfamily C, member 6

decreases expression

sulforaphane results in decreased expression of TRPC6 mRNA

NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:5,758,935...5,828,092

G

transcriptional repressor GATA binding 1

increases expression

sulforaphane results in increased expression of TRPS1 mRNA

NCBI chr 7:83,806,121...84,032,609
Ensembl chr 7:81,921,601...82,141,905

G

TSC22 domain family, member 3

decreases expression

sulforaphane results in decreased expression of TSC22D3 mRNA

NCBI chr X:109,006,410...109,066,389
Ensembl chr X:104,217,925...104,276,861

G

teashirt zinc finger homeobox 2

decreases expression

sulforaphane results in decreased expression of TSHZ2 mRNA

NCBI chr 3:178,824,221...179,271,151
Ensembl chr 3:158,405,423...158,850,128

G

tetraspanin 1

increases expression

sulforaphane results in increased expression of TSPAN1 mRNA

NCBI chr 5:134,883,704...134,896,083
Ensembl chr 5:129,646,993...129,652,017

G

tetraspanin 14

increases expression

sulforaphane results in increased expression of TSPAN14 mRNA

NCBI chr16:16,818,344...16,875,462
Ensembl chr16:16,783,234...16,841,400

G

tetraspanin 2

decreases expression

sulforaphane results in decreased expression of TSPAN2 mRNA

NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660

G

TSPO associated protein 1

decreases expression

sulforaphane results in decreased expression of TSPOAP1 mRNA

NCBI chr10:73,053,414...73,083,640
Ensembl chr10:72,560,980...72,586,412

G

tetratricopeptide repeat domain 39A

increases expression

sulforaphane results in increased expression of TTC39A mRNA

NCBI chr 5:129,379,560...129,441,779
Ensembl chr 5:124,151,760...124,204,973

G

tetratricopeptide repeat domain 7A

decreases expression

sulforaphane results in decreased expression of TTC7A mRNA

NCBI chr 6:12,912,822...13,015,374
Ensembl chr 6:7,159,061...7,261,892

G

Ttk protein kinase

increases expression

sulforaphane results in increased expression of TTK mRNA

NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:84,754,315...84,792,651

G

tubulin tyrosine ligase like 7

decreases expression

sulforaphane results in decreased expression of TTLL7 mRNA

NCBI chr 2:238,425,786...238,549,296
Ensembl chr 2:235,765,835...235,885,047

G

titin

increases expression

sulforaphane results in increased expression of TTN mRNA

NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741

G

alpha tocopherol transfer protein

decreases expression

sulforaphane results in decreased expression of TTPA mRNA

NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:33,497,137...33,518,073

G

tubulin, alpha 1A

affects binding

TUBA1A protein binds to sulforaphane

NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, alpha 3B

affects binding

TUBA3D protein binds to sulforaphane

NCBI chr 4:180,319,600...180,325,149
Ensembl chr 4:178,588,779...178,594,326

G

tubulin, alpha 4A

increases acetylation
affects binding
increases expression

sulforaphane results in increased acetylation of TUBA4A protein
TUBA4A protein binds to sulforaphane
sulforaphane results in increased expression of TUBA4A mRNA

PMID:19805354 PMID:21838287 PMID:26833863 PMID:31838189

NCBI chr 9:84,158,871...84,174,041
Ensembl chr 9:76,709,614...76,713,918

G

tubulin, beta 1 class VI

affects binding
multiple interactions

TUBB1 protein binds to sulforaphane
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of TUBB1 mRNA

PMID:21838287 PMID:30529165

NCBI chr 3:183,666,189...183,675,656
Ensembl chr 3:163,247,967...163,256,063

G

tubulin, beta 4A class IVa

decreases expression

sulforaphane results in decreased expression of TUBB4A mRNA

NCBI chr 9:2,004,836...2,012,281
Ensembl chr 9:1,917,845...1,925,291

G

tubulin, beta 4B class IVb

affects binding
increases expression

TUBB4B protein binds to sulforaphane
sulforaphane results in increased expression of TUBB4B mRNA

PMID:21838287 PMID:31838189

NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:8,037,799...8,040,296

G

trans-golgi network vesicle protein 23 homolog A

increases expression

sulforaphane results in increased expression of TVP23A mRNA

NCBI chr10:5,734,100...5,770,002
Ensembl chr10:5,227,220...5,263,180

G

taxilin beta

increases expression

sulforaphane results in increased expression of TXLNB mRNA

NCBI chr 1:14,224,647...14,269,837
Ensembl chr 1:12,404,859...12,449,975

G

taxilin gamma

decreases expression

sulforaphane results in decreased expression of TXLNG mRNA

NCBI chr X:35,495,822...35,544,716
Ensembl chr X:31,864,111...31,912,926

G

thioredoxin 1

increases expression
decreases methylation
multiple interactions

sulforaphane metabolite results in increased expression of TXN mRNA; sulforaphane results in increased expression of TXN mRNA; sulforaphane results in increased expression of TXN protein
sulforaphane results in decreased methylation of TXN gene
sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TXN mRNA]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TXN mRNA]

PMID:19123792 PMID:20442190 PMID:25683455 PMID:31838189 PMID:32387680

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin reductase 1

multiple interactions
increases activity
decreases activity
increases expression
decreases expression

1-(5-isoquinolinylsulfonyl)-3-methylpiperazine inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; [sulforaphane co-treated with Selenium] results in increased activity of TXNRD1 protein; [sulforaphane co-treated with Sodium Selenite] results in increased activity of TXNRD1 protein; Buthionine Sulfoximine inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; Dactinomycin inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of TXNRD1 protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of TXNRD1 protein]; Selenium promotes the reaction [sulforaphane results in increased expression of and results in increased activity of TXNRD1 protein]; Sodium Selenite promotes the reaction [sulforaphane results in increased activity of TXNRD1 protein]; Sodium Selenite promotes the reaction [sulforaphane results in increased expression of TXNRD1 mRNA]; Sodium Selenite promotes the reaction [sulforaphane results in increased expression of TXNRD1 protein]; sulforaphane metabolite promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TXNRD1 mRNA]; sulforaphane promotes the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of TXNRD1 mRNA]; sulforaphane results in increased expression of and results in increased activity of TXNRD1 protein
sulforaphane results in decreased activity of TXNRD1 protein
sulforaphane results in increased expression of TXNRD1 mRNA; sulforaphane results in increased expression of TXNRD1 protein
sulforaphane metabolite results in increased expression of TXNRD1 mRNA; sulforaphane results in increased expression of TXNRD1 mRNA; sulforaphane results in increased expression of TXNRD1 protein
sulforaphane results in decreased expression of TXNRD1 mRNA

PMID:12663510 PMID:12949356 PMID:15740016 PMID:17150329 PMID:17937621 More...

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863

G

tyrosinase

decreases expression

sulforaphane results in decreased expression of TYR mRNA

NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:141,115,036...141,210,207

G

transmembrane immune signaling adaptor Tyrobp

increases expression

sulforaphane results in increased expression of TYROBP mRNA

NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:85,672,994...85,676,848

G

ubiquitin-conjugating enzyme E2D 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of UBE2D3 mRNA

NCBI chr 2:226,543,194...226,571,001
Ensembl chr 2:223,868,730...223,898,081

G

ubiquitin-conjugating enzyme E2S

increases expression

sulforaphane results in increased expression of UBE2S mRNA

NCBI chr 1:78,057,659...78,061,719
Ensembl chr 1:69,028,750...69,032,914

G

UBX domain protein 2A

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of UBXN2A mRNA

NCBI chr 6:33,603,804...33,645,958
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649

G

UDP-glucose 6-dehydrogenase

increases expression

sulforaphane results in increased expression of UGDH mRNA

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase family 1 member A1

multiple interactions
decreases expression
increases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of UGT1A1 mRNA]; [sulforaphane co-treated with Apigenin] results in increased expression of UGT1A1 mRNA
sulforaphane results in decreased expression of UGT1A1 mRNA
sulforaphane results in increased expression of UGT1A1 mRNA; sulforaphane results in increased expression of UGT1A1 protein

PMID:12151360 PMID:12756216 PMID:12949046 PMID:15090468 PMID:15896333

NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465

G

unk like zinc finger

increases expression

sulforaphane results in increased expression of UNKL mRNA

NCBI chr10:14,710,627...14,756,725
Ensembl chr10:14,206,189...14,252,225

G

uroplakin 3B

decreases expression

sulforaphane results in decreased expression of UPK3B mRNA

NCBI chr12:26,266,838...26,274,240
Ensembl chr12:20,631,525...20,637,724

G

uridine phosphorylase 1

increases expression

sulforaphane results in increased expression of UPP1 mRNA

NCBI chr14:88,023,155...88,043,036
Ensembl chr14:83,809,960...83,829,462

G

ubiquinol-cytochrome c reductase, complex III subunit XI

increases expression

sulforaphane results in increased expression of UQCR11 mRNA

NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,305,058...9,309,750

G

ubiquinol-cytochrome c reductase core protein 1

increases expression

sulforaphane results in increased expression of UQCRC1 mRNA

NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:109,589,706...109,601,480

G

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

increases expression

sulforaphane results in increased expression of UQCRFS1 mRNA

NCBI chr17:34,173,787...34,190,952
Ensembl chr17:33,977,921...33,982,479

G

ubiquinol-cytochrome c reductase, complex III subunit VII

increases expression

sulforaphane results in increased expression of UQCRQ mRNA

NCBI chr10:38,086,691...38,093,871
Ensembl chr10:37,586,888...37,589,169

G

USH1 protein network component harmonin

decreases expression

sulforaphane results in decreased expression of USH1C mRNA

NCBI chr 1:105,831,719...105,880,082
Ensembl chr 1:96,695,307...96,743,671

G

ubiquitin specific peptidase 12

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of USP12 mRNA

NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656

G

ubiquitin specific peptidase 2

decreases expression
multiple interactions

sulforaphane results in decreased expression of USP2 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of USP2 mRNA

PMID:26833863 PMID:30529165

NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:44,411,607...44,438,331

G

ubiquitin specific peptidase 33

decreases expression

sulforaphane results in decreased expression of USP33 mRNA

NCBI chr 2:243,938,958...243,988,424
Ensembl chr 2:241,292,985...241,328,479

G

ubiquitin specific peptidase 43

decreases expression

sulforaphane results in decreased expression of USP43 mRNA

NCBI chr10:53,047,368...53,110,099
Ensembl chr10:52,548,963...52,611,533

G

ubiquitin specific peptidase 5

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of USP5 mRNA

NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:157,619,643...157,634,711

G

vasohibin 2

decreases expression

sulforaphane results in decreased expression of VASH2 mRNA

NCBI chr13:105,060,857...105,092,325
Ensembl chr13:102,529,719...102,560,391

G

vascular cell adhesion molecule 1

multiple interactions
increases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of VCAM1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in increased expression of VCAM1 protein]
sulforaphane results in increased expression of VCAM1 mRNA

PMID:24707343 PMID:30096613 PMID:35724838

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

valosin-containing protein

affects binding

VCP protein binds to sulforaphane

NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:57,210,168...57,229,571

G

voltage-dependent anion channel 1

multiple interactions

NFE2L2 protein affects the reaction [sulforaphane promotes the reaction [Oxygen results in increased expression of VDAC1 protein]]; sulforaphane promotes the reaction [Oxygen results in increased expression of VDAC1 protein]

NCBI chr10:37,029,377...37,060,542
Ensembl chr10:36,532,244...36,559,640

G

vascular endothelial growth factor A

decreases expression

sulforaphane results in decreased expression of VEGFA mRNA

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor B

increases expression

sulforaphane results in increased expression of VEGFB mRNA

NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:204,172,225...204,177,944

G

vascular endothelial growth factor D

decreases expression

sulforaphane results in decreased expression of VEGFD mRNA

NCBI chr X:33,704,582...33,740,305
Ensembl chr X:30,074,163...30,108,295

G

vestigial-like family member 3

decreases expression

sulforaphane results in decreased expression of VGLL3 mRNA

NCBI chr11:17,089,484...17,136,501
Ensembl chr11:3,643,069...3,689,140

G

villin-like

increases expression

sulforaphane results in increased expression of VILL mRNA

NCBI chr 8:127,654,491...127,672,742
Ensembl chr 8:118,776,742...118,794,983

G

vimentin

affects binding
multiple interactions

VIM protein binds to sulforaphane
sulforaphane inhibits the reaction [Paraquat results in increased expression of VIM protein]

PMID:21838287 PMID:28624451

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

G

vasoactive intestinal peptide receptor 2

decreases expression

sulforaphane results in decreased expression of VIPR2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 6:143,139,672...143,213,609
Ensembl chr 6:137,001,511...137,070,597

G

vitrin

increases expression
decreases expression

sulforaphane results in increased expression of VIT mRNA
sulforaphane results in decreased expression of VIT mRNA

PMID:30529165 PMID:31838189

NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665

G

V-set and immunoglobulin domain containing 2

decreases expression

sulforaphane results in decreased expression of VSIG2 mRNA

NCBI chr 8:45,438,865...45,443,908
Ensembl chr 8:37,250,107...37,255,150

G

V-set immunoregulatory receptor

decreases expression

sulforaphane results in decreased expression of VSIR mRNA

NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878

G

vitronectin

decreases expression

sulforaphane results in decreased expression of VTN mRNA

NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,394,719...63,397,810

G

von Willebrand factor A domain containing 5A

decreases expression

sulforaphane results in decreased expression of VWA5A mRNA

NCBI chr 8:47,712,352...47,745,847
Ensembl chr 8:38,815,210...38,839,112

G

von Willebrand factor A domain containing 7

decreases expression

sulforaphane results in decreased expression of VWA7 mRNA

NCBI chr20:3,794,991...3,805,646
Ensembl chr20:3,794,991...3,805,525

G

WASP family member 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of WASF2 mRNA

NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:145,336,842...145,399,242

G

WD repeat domain 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of WDR3 mRNA

NCBI chr 2:190,194,474...190,217,087
Ensembl chr 2:187,505,816...187,528,432

G

WD repeat domain 44

decreases expression

sulforaphane results in decreased expression of WDR44 mRNA

NCBI chr X:119,286,802...119,392,240
Ensembl chr X:114,482,006...114,587,224

G

WD repeat domain 54

decreases expression

sulforaphane results in decreased expression of WDR54 mRNA

NCBI chr 4:117,212,677...117,236,456
Ensembl chr 4:115,654,968...115,661,562

G

WD repeat domain 75

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of WDR75 mRNA

NCBI chr 9:55,395,232...55,425,412
Ensembl chr 9:47,903,200...47,933,399

G

WD repeat domain 76

decreases expression

sulforaphane results in decreased expression of WDR76 mRNA

NCBI chr 3:128,910,500...128,945,241
Ensembl chr 3:108,456,815...108,490,840

G

Wnt family member 6

decreases expression

sulforaphane results in decreased expression of WNT6 mRNA

NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523

G

XIAP associated factor 1

decreases expression

sulforaphane results in decreased expression of XAF1 mRNA

NCBI chr10:57,415,935...57,428,348
Ensembl chr10:56,917,121...56,929,770

G

X-box binding protein 1

multiple interactions

sulforaphane inhibits the reaction [bisphenol A results in increased expression of XBP1 protein alternative form]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased splicing of XBP1 mRNA]

PMID:22922937 PMID:36670177

NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693

G

X-linked inhibitor of apoptosis

decreases expression

sulforaphane results in decreased expression of XIAP protein

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:120,897,907...120,934,700

G

exportin for tRNA

increases expression

sulforaphane results in increased expression of XPOT mRNA

NCBI chr 7:58,997,025...59,037,506
Ensembl chr 7:57,111,536...57,152,099

G

tyrosyl-tRNA synthetase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of YARS1 mRNA

NCBI chr 5:146,820,163...146,848,377
Ensembl chr 5:141,535,759...141,563,833

G

Yip1 domain family, member 7

increases expression

sulforaphane results in increased expression of YIPF7 mRNA

NCBI chr14:38,924,994...38,953,021
Ensembl chr14:38,571,066...38,599,055

G

YjeF N-terminal domain containing 3

increases expression

sulforaphane results in increased expression of YJEFN3 mRNA

NCBI chr16:19,567,565...19,573,667
Ensembl chr16:19,533,788...19,539,728

G

yippee-like 3

decreases expression

sulforaphane results in decreased expression of YPEL3 mRNA

NCBI chr 1:190,814,920...190,818,248
Ensembl chr 1:181,384,357...181,387,705

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

affects binding

YWHAB protein binds to sulforaphane

NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:152,659,651...152,682,105

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

affects binding

YWHAE protein binds to sulforaphane

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

affects binding

YWHAQ protein binds to sulforaphane

NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:40,935,949...40,966,273

G

zinc finger and BTB domain containing 18

increases expression

sulforaphane results in increased expression of ZBTB18 mRNA

NCBI chr13:91,971,602...91,980,058
Ensembl chr13:89,439,420...89,448,862

G

zinc finger CCCH-type containing 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZC3H4 mRNA

NCBI chr 1:86,234,457...86,271,963
Ensembl chr 1:77,106,250...77,142,691

G

zinc finger, DHHC-type containing 11

increases expression

sulforaphane results in increased expression of ZDHHC11 mRNA

NCBI chr 1:31,124,900...31,156,075
Ensembl chr 1:29,296,334...29,326,898

G

zinc finger DHHC-type palmitoyltransferase 16

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZDHHC16 mRNA

NCBI chr 1:240,745,606...240,757,009
Ensembl chr 1:240,745,641...240,757,009

G

zinc finger DHHC-type palmitoyltransferase 3

increases expression
decreases expression

sulforaphane results in increased expression of ZDHHC3 mRNA
sulforaphane results in decreased expression of ZDHHC3 mRNA

PMID:26833863 PMID:30529165

NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529

G

zinc finger E-box binding homeobox 1

increases expression

sulforaphane results in increased expression of ZEB1 mRNA

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

decreases expression

sulforaphane results in decreased expression of ZEB2 mRNA

NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157

G

zyg-11 related, cell cycle regulator

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZER1 mRNA

NCBI chr 3:33,767,520...33,806,716
Ensembl chr 3:13,369,688...13,397,420

G

zinc finger AN1-type containing 2A

decreases expression

sulforaphane results in decreased expression of ZFAND2A mRNA

NCBI chr12:20,275,435...20,286,513
Ensembl chr12:15,161,639...15,172,677

G

zinc finger protein 462

decreases expression

sulforaphane results in decreased expression of ZNF462 mRNA

NCBI chr 5:74,465,383...74,606,020
Ensembl chr 5:69,670,328...69,810,327

G

zinc finger protein 521

decreases expression

sulforaphane results in decreased expression of ZNF521 mRNA

NCBI chr18:5,050,297...5,343,188
Ensembl chr18:4,787,295...5,068,458

G

zinc finger protein 58

affects binding

ZNF429 protein binds to sulforaphane

NCBI chr 1:36,848,858...36,861,605
Ensembl chr 1:35,002,321...35,033,216

G

zinc finger protein 608

decreases expression

sulforaphane results in decreased expression of ZNF608 mRNA

NCBI chr18:50,503,043...50,611,019
Ensembl chr18:48,304,880...48,410,465

G

zinc finger protein 612

decreases expression

sulforaphane results in decreased expression of ZFP612 mRNA

NCBI chr19:54,963,400...54,976,888
Ensembl chr19:38,053,967...38,067,455

G

zinc finger protein 62

decreases expression

sulforaphane results in decreased expression of ZFP62 mRNA

NCBI chr10:34,019,367...34,040,564
Ensembl chr10:33,500,323...33,542,013

G

zinc finger protein 644

decreases expression

sulforaphane results in decreased expression of ZFP644 mRNA

NCBI chr14:3,248,350...3,324,820
Ensembl chr14:3,105,178...3,179,940

G

zinc finger protein 712

increases expression

sulforaphane results in increased expression of ZNF28 mRNA

NCBI chr 2:86,139,430...86,187,530
Ensembl chr 2:84,432,276...84,467,360

G

zinc finger protein 746

increases expression

sulforaphane results in increased expression of ZNF746 mRNA

NCBI chr 4:78,385,945...78,410,240
Ensembl chr 4:77,055,008...77,078,897

G

zinc finger protein 831

decreases expression

sulforaphane results in decreased expression of ZNF831 mRNA

NCBI chr 3:183,811,489...183,931,900
Ensembl chr 3:163,438,006...163,509,095

G

ZFP92 zinc finger protein

increases expression

sulforaphane results in increased expression of ZFP92 mRNA

NCBI chr X:156,268,220...156,293,790
Ensembl chr X:151,117,102...151,143,177

G

zinc finger, matrin type 3

decreases expression
multiple interactions

sulforaphane results in decreased expression of ZMAT3 mRNA
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZMAT3 mRNA

NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:115,106,966...115,136,863

G

zinc finger, MYND-type containing 12

decreases expression

sulforaphane results in decreased expression of ZMYND12 mRNA

NCBI chr 5:138,312,257...138,345,269
Ensembl chr 5:133,027,009...133,059,995

G

zona pellucida glycoprotein 3

increases expression

sulforaphane results in increased expression of ZP3 mRNA

NCBI chr12:26,327,161...26,334,126
Ensembl chr12:20,690,547...20,697,513

G

zinc finger and SCAN domain containing 5B

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZSCAN5B mRNA

NCBI chr 1:76,699,772...76,707,325
Ensembl chr 1:67,666,691...67,674,238

G

ZW10 interacting kinetochore protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZWINT mRNA

NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,938,157...15,953,957

G

ZXD family zinc finger C

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZXDA mRNA

NCBI chr 4:124,439,560...124,471,694
Ensembl chr 4:122,882,336...122,916,496

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19909
role	19880
chemical role	19506
antioxidant	16196
sulforaphane	1834
(R)-sulforaphane	0
(S)-sulforaphane	0
Path 2
Term	Annotations
CHEBI ontology	19909
subatomic particle	19907
composite particle	19907
hadron	19907
baryon	19907
nucleon	19907
atomic nucleus	19907
atom	19907
main group element atom	19846
p-block element atom	19846
carbon group element atom	19784
carbon atom	19781
organic molecular entity	19781
heteroorganic entity	19540
organochalcogen compound	19301
organosulfur compound	17518
sulfoxide	6533
sulforaphane	1834
(R)-sulforaphane	0
(S)-sulforaphane	0

paths to the root