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ONTOLOGY REPORT - ANNOTATIONS


Term:emedastine
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Accession:CHEBI:4779 term browser browse the term
Definition:1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
Synonyms:exact_synonym: 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
 related_synonym: 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole;   1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole;   1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole;   Formula=C17H26N4O;   InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3;   InChIKey=KBUZBQVCBVDWKX-UHFFFAOYSA-N;   SMILES=CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1;   emedastina;   emedastinum
 alt_id: CHEBI:119712
 xref: Beilstein:6068161;   CAS:87233-61-2;   DrugBank:DB01084;   Drug_Central:999;   KEGG:C07785;   KEGG:D07890;   LINCS:LSM-5331
 xref_mesh: MESH:C043345
 xref: Patent:US4430343;   Wikipedia:Emedastine


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emedastine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      application 19385
        pharmaceutical 19254
          drug 19254
            anti-allergic agent 3795
              emedastine 1
                emedastine difumarate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      p-block molecular entity 19674
                        carbon group molecular entity 19572
                          organic molecular entity 19561
                            organic molecule 19483
                              organic cyclic compound 19246
                                organic heterocyclic compound 18366
                                  organic heteropolycyclic compound 17709
                                    organic heterobicyclic compound 16486
                                      benzimidazoles 846
                                        emedastine 1
                                          emedastine difumarate 0
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