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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:AMP-PNP
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Accession:CHEBI:47785 term browser browse the term
Definition:An adenosine 5'-phosphate that has formula C10H17N6O12P3.
Synonyms:exact_synonym: 5'-O-(hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl)adenosine
 related_synonym: AMPPNP;   Adenylyl imidodiphosphate;   Formula=C10H17N6O12P3;   InChI=1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1;   InChIKey=PVKSNHVPLWYQGJ-KQYNXXCUSA-N;   O(5')-(1,2-dihydroxy-2-phosphonoaminodiphosphoryl)adenosine;   SMILES=Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O;   adenyl-5'-yl imidodiphosphate;   gamma-Imino-ATP
 xref: Beilstein:1064472;   CAS:25612-73-1
 xref_mesh: MESH:D000266


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AMP-PNP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions ISO Adenylyl Imidodiphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CFTR CF transmembrane conductance regulator affects activity EXP Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 affects binding EXP Adenylyl Imidodiphosphate binds to CSNK2A1 protein CTD PMID:34344863 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G PTGDR prostaglandin D2 receptor multiple interactions EXP Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        pharmacological role 22058
          analgesic 15532
            adenosine 410
              adenosine phosphate 305
                adenosine 5'-phosphate 304
                  AMP-PNP 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      chalcogen 24917
                        oxygen atom 24817
                          oxygen molecular entity 24806
                            hydroxides 24049
                              oxoacid 22975
                                pnictogen oxoacid 13799
                                  phosphorus oxoacid 12848
                                    phosphoric acids 11880
                                      phosphoric acid 11872
                                        phosphoric acid derivative 11674
                                          phosphate 11673
                                            organic phosphate 11673
                                              carbohydrate phosphate 1897
                                                phospho sugar 1742
                                                  aldose phosphate 1739
                                                    aldopentose phosphate 1731
                                                      ribose phosphate 1724
                                                        ribonucleotide 1683
                                                          purine ribonucleotide 1650
                                                            adenyl ribonucleotide 1348
                                                              adenosine phosphate 305
                                                                adenosine 5'-phosphate 304
                                                                  AMP-PNP 4
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