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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclopentafuran
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Accession:CHEBI:47783 term browser browse the term
Synonyms:related_synonym: cyclopentafurans


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prostaglandin I2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Agt angiotensinogen multiple interactions
increases abundance 		EXP 1-Butanol inhibits the reaction [AGT protein results in increased abundance of Epoprostenol]; arachidonyltrifluoromethane inhibits the reaction [AGT protein results in increased abundance of Epoprostenol]; midostaurin inhibits the reaction [AGT protein results in increased abundance of Epoprostenol]; PTGS2 protein affects the reaction [AGT protein results in increased abundance of Epoprostenol]
AGT protein results in increased abundance of Epoprostenol; AGT results in increased abundance of Epoprostenol 		CTD PMID:3888613 PMID:14613874 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Epoprostenol results in increased expression of CCL2 protein CTD PMID:15302794 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Fbn1 fibrillin 1 multiple interactions ISO FBN1 protein affects the reaction [Phenylephrine results in increased secretion of Epoprostenol metabolite] CTD PMID:17641673 NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP IL10 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Epoprostenol] CTD PMID:12632514 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1a interleukin 1 alpha increases abundance ISO IL1A protein results in increased abundance of Epoprostenol CTD PMID:21513769 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases secretion EXP IL1B protein results in increased secretion of Epoprostenol CTD PMID:11882577 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Kng1 kininogen 1 increases abundance EXP KNG1 results in increased abundance of Epoprostenol CTD PMID:3888613 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity ISO Epoprostenol results in increased activity of MAPK1 protein CTD PMID:19201774 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity ISO Epoprostenol results in increased activity of MAPK3 protein CTD PMID:19201774 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions
increases abundance 		ISO 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulfonyl)phenyl-2(5H)-furanone inhibits the reaction [PDGFA results in increased abundance of Epoprostenol]; celecoxib inhibits the reaction [PDGFA results in increased abundance of Epoprostenol]; Ibuprofen inhibits the reaction [PDGFA results in increased abundance of Epoprostenol]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [PDGFA results in increased abundance of Epoprostenol] CTD PMID:19201774 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Epoprostenol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP PTGS2 protein affects the reaction [AGT protein results in increased abundance of Epoprostenol] CTD PMID:14613874 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    chemical entity 20854
      atom 20854
        nonmetal atom 20762
          oxygen atom 20455
            oxygen molecular entity 20455
              organooxygen compound 19804
                oxacycle 18292
                  cyclopentafuran 13
                    N-s-butyl-N-[(2R,3S)-3-(\{[(3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yloxy]carbonyl\}amino)-2-hydroxy-4-phenylbutyl]-4-(hydroxymethyl)benzenesulfonamide 0
                    prostaglandins I + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            organic molecule 20649
                              organic cyclic compound 20400
                                organic heterocyclic compound 19383
                                  organic heteropolycyclic compound 18642
                                    organic heterobicyclic compound 17527
                                      cyclopentafuran 13
                                        N-s-butyl-N-[(2R,3S)-3-(\{[(3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yloxy]carbonyl\}amino)-2-hydroxy-4-phenylbutyl]-4-(hydroxymethyl)benzenesulfonamide 0
                                        prostaglandins I + 13
paths to the root