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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:47619 term browser browse the term
Definition:A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.
Synonyms:related_synonym: 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide;   3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-p-anisamide;   3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide;   Formula=C18H18Cl2N2O3;   InChI=1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)22-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23);   InChIKey=RRRUXBQSQLKHEL-UHFFFAOYSA-N;   RP 73-401;   RP 73401;   SMILES=COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)cncc1Cl;   piclamilastum
 xref: CAS:144035-83-6;   DrugBank:DB01791;   KEGG:D05474
 xref_mesh: MESH:C087566
 xref: PDBeChem:PIL;   PMID:10485818;   PMID:22360706;   PMID:7647982;   PMID:7889300;   PMID:8864527;   PMID:9316851;   Reaxys:6937319;   Wikipedia:Piclamilast

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piclamilast term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of piclamilast CTD PMID:12464242 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Epx eosinophil peroxidase multiple interactions EXP piclamilast inhibits the reaction [sephadex results in increased expression of EPX protein] CTD PMID:10850854 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        anti-inflammatory agent 15836
          piclamilast 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        carboacyl group 17482
                                          univalent carboacyl group 17482
                                            carbamoyl group 17298
                                              carboxamide 17298
                                                monocarboxylic acid amide 15014
                                                  arenecarboxamide 7265
                                                    benzamides 7265
                                                      piclamilast 2
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