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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:furosemide
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Accession:CHEBI:47426 term browser browse the term
Definition:A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.
Synonyms:exact_synonym: 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
 related_synonym: 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid;   4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid;   4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid;   4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid;   Formula=C12H11ClN2O5S;   Frusemide;   InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);   InChIKey=ZZUFCTLCJUWOSV-UHFFFAOYSA-N;   Lasix (TN);   SMILES=NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
 alt_id: CHEBI:47425;   CHEBI:5198
 xref: CAS:54-31-9;   DrugBank:DB00695;   Drug_Central:1258;   HMDB:HMDB0001933;   KEGG:D00331;   LINCS:LSM-5847
 xref_mesh: MESH:D005665
 xref: PMID:15286542;   PMID:18701232;   Reaxys:1399731;   VSDB:1770;   Wikipedia:Furosemide


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furosemide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO
EXP
Furosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
[Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]
CTD PMID:12704183 PMID:19782883 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Furosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12704183 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases export
increases transport
ISO ABCC4 protein results in increased export of Furosemide
ABCC4 protein results in increased transport of Furosemide
CTD PMID:17135398 PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 affects expression EXP Furosemide affects the expression of ADAMTS1 mRNA CTD PMID:16526316 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Agt angiotensinogen increases expression ISO Furosemide results in increased expression of AGT protein modified form CTD PMID:18081357 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation EXP Furosemide affects the phosphorylation of AKT1 protein CTD PMID:17497460 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions
affects binding
ISO [bucolome inhibits the reaction [Furosemide binds to ALB protein]] which affects the abundance of Furosemide; bucolome inhibits the reaction [Furosemide binds to ALB protein] CTD PMID:15640375 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Furosemide results in increased expression of ALDH1A1 mRNA CTD PMID:28138970 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Ang angiogenin affects expression EXP Furosemide affects the expression of ANG mRNA CTD PMID:16526316 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Angpt2 angiopoietin 2 affects expression EXP Furosemide affects the expression of ANGPT2 mRNA CTD PMID:16526316 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 affects expression EXP Furosemide affects the expression of APAF1 mRNA CTD PMID:17497460 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Aqp2 aquaporin 2 increases expression EXP Furosemide results in increased expression of AQP2 mRNA; Furosemide results in increased expression of AQP2 protein CTD PMID:17584643 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression EXP Furosemide affects the expression of ARC mRNA CTD PMID:17497460 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases secretion ISO ARNTL gene mutant form results in decreased secretion of Furosemide CTD PMID:27056296 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Atm ATM serine/threonine kinase affects expression EXP Furosemide affects the expression of ATM mRNA CTD PMID:17497460 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 multiple interactions
increases expression
EXP [Furosemide co-treated with Amiloride] results in increased expression of ATP6V1B1 protein
Furosemide results in increased expression of ATP6V1B1 protein
CTD PMID:17311909 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Avpr2 arginine vasopressin receptor 2 increases expression EXP Furosemide results in increased expression of AVPR2 mRNA CTD PMID:17584643 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression EXP Furosemide affects the expression of BAD mRNA CTD PMID:17497460 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 affects expression EXP Furosemide affects the expression of BAK1 mRNA CTD PMID:17497460 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression EXP Furosemide affects the expression of BAX mRNA CTD PMID:17497460 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression EXP Furosemide affects the expression of BCL10 mRNA CTD PMID:17497460 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression EXP Furosemide affects the expression of BCL2 mRNA CTD PMID:17497460 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l10 BCL2 like 10 affects expression EXP Furosemide affects the expression of BCL2L10 mRNA CTD PMID:17497460 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l11 BCL2 like 11 affects expression EXP Furosemide affects the expression of BCL2L11 mRNA CTD PMID:17497460 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l2 Bcl2-like 2 affects expression EXP Furosemide affects the expression of BCL2L2 mRNA CTD PMID:17497460 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bid BH3 interacting domain death agonist affects expression EXP Furosemide affects the expression of BID mRNA CTD PMID:17497460 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer affects expression EXP Furosemide affects the expression of BIK mRNA CTD PMID:17497460 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects expression EXP Furosemide affects the expression of BIRC2 mRNA CTD PMID:17497460 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects expression EXP Furosemide affects the expression of BIRC5 mRNA CTD PMID:17497460 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 affects expression EXP Furosemide affects the expression of BIRC6 mRNA CTD PMID:17497460 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Bok BCL2 family apoptosis regulator BOK affects expression EXP Furosemide affects the expression of BOK mRNA CTD PMID:17497460 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta decreases expression EXP Furosemide results in decreased expression of BSND mRNA CTD PMID:12759757 NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571
JBrowse link
G Calb1 calbindin 1 increases expression ISO Furosemide results in increased expression of CALB1 mRNA; Furosemide results in increased expression of CALB1 protein CTD PMID:17652376 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity
increases expression
ISO
EXP
Furosemide results in decreased activity of CA2 protein
Furosemide results in increased expression of CA2 mRNA
CTD PMID:16858005 PMID:28138970 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp1 caspase 1 affects expression EXP Furosemide affects the expression of CASP1 mRNA CTD PMID:17497460 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 affects expression EXP Furosemide affects the expression of CASP12 mRNA CTD PMID:17497460 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp14 caspase 14 affects expression EXP Furosemide affects the expression of CASP14 mRNA CTD PMID:17497460 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Casp2 caspase 2 affects expression EXP Furosemide affects the expression of CASP2 mRNA CTD PMID:17497460 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 affects expression EXP Furosemide affects the expression of CASP3 mRNA CTD PMID:17497460 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 affects expression EXP Furosemide affects the expression of CASP4 mRNA CTD PMID:17497460 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 affects expression EXP Furosemide affects the expression of CASP6 mRNA CTD PMID:17497460 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 affects expression EXP Furosemide affects the expression of CASP8 mRNA CTD PMID:17497460 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 affects expression EXP Furosemide affects the expression of CASP9 mRNA CTD PMID:17497460 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cd40 CD40 molecule affects expression EXP Furosemide affects the expression of CD40 mRNA CTD PMID:17497460 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd70 Cd70 molecule affects expression EXP Furosemide affects the expression of CD70 mRNA CTD PMID:17497460 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
JBrowse link
G Cdh5 cadherin 5 decreases expression EXP Furosemide results in decreased expression of CDH5 mRNA CTD PMID:16526316 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Chek1 checkpoint kinase 1 affects expression EXP Furosemide affects the expression of CHEK1 mRNA CTD PMID:17497460 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 affects expression EXP Furosemide affects the expression of CHEK2 mRNA CTD PMID:17497460 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chga chromogranin A increases expression EXP Furosemide results in increased expression of CHGA mRNA CTD PMID:16526316 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP Furosemide affects the expression of CIDEA mRNA CTD PMID:17497460 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression EXP Furosemide affects the expression of CIDEB mRNA CTD PMID:17497460 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression EXP Furosemide results in decreased expression of CLCNKA mRNA CTD PMID:12759757 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP Furosemide results in decreased expression of COL18A1 mRNA CTD PMID:16526316 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain affects expression EXP Furosemide affects the expression of CRADD mRNA CTD PMID:17497460 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP Furosemide results in increased expression of CSF3 mRNA CTD PMID:16526316 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Dapk2 death-associated protein kinase 2 affects expression EXP Furosemide affects the expression of DAPK2 mRNA CTD PMID:17497460 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Furosemide results in increased expression of DDIT3 mRNA CTD PMID:24813929 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dffa DNA fragmentation factor subunit alpha affects expression EXP Furosemide affects the expression of DFFA mRNA CTD PMID:17497460 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Efna5 ephrin A5 increases expression EXP Furosemide results in increased expression of EFNA5 mRNA CTD PMID:16526316 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
JBrowse link
G Fadd Fas associated via death domain affects expression EXP Furosemide affects the expression of FADD mRNA CTD PMID:17497460 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faslg Fas ligand affects expression EXP Furosemide affects the expression of FASLG mRNA CTD PMID:17497460 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf16 fibroblast growth factor 16 affects expression EXP Furosemide affects the expression of FGF16 mRNA CTD PMID:16526316 NCBI chr  X:70,816,658...70,827,270
Ensembl chr  X:70,817,433...70,878,717
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Furosemide results in decreased expression of FGF2 mRNA CTD PMID:16526316 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression EXP Furosemide results in increased expression of FGF4 mRNA CTD PMID:16526316 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects expression EXP Furosemide affects the expression of FGFR4 mRNA CTD PMID:16526316 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression EXP Furosemide results in increased expression of FLT1 mRNA CTD PMID:16526316 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Furosemide results in increased expression of FOS protein
Losartan inhibits the reaction [Furosemide results in increased expression of FOS protein]
CTD PMID:10760498 PMID:15528393 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP Furosemide results in decreased activity of G6PD protein CTD PMID:26820767 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases activity EXP Furosemide results in decreased activity of GABRA4 protein CTD PMID:15613639 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP Furosemide results in decreased expression of GAD1 mRNA CTD PMID:14596865 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression EXP Furosemide affects the expression of GADD45A mRNA CTD PMID:17497460 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP Furosemide results in decreased activity of GSR protein CTD PMID:26820767 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMGB1 protein; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMGB1 protein CTD PMID:29860548 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Furosemide results in increased expression of HMOX1 mRNA
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMOX1 mRNA; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMOX1 mRNA
CTD PMID:24813929 PMID:29860548 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrk harakiri, BCL2 interacting protein affects expression EXP Furosemide affects the expression of HRK mRNA CTD PMID:17497460 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity EXP Furosemide results in decreased activity of HSD11B1 protein CTD PMID:11749789 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hus1 HUS1 checkpoint clamp component affects expression EXP Furosemide affects the expression of HUS1 mRNA CTD PMID:17497460 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression EXP Furosemide results in decreased expression of ID1 mRNA CTD PMID:16526316 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression EXP Furosemide results in decreased expression of ID3 mRNA CTD PMID:16526316 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ifna1 interferon, alpha 1 increases expression EXP Furosemide results in increased expression of IFNA1 mRNA CTD PMID:16526316 NCBI chr 5:103,095,767...103,098,260 JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Furosemide results in increased expression of IGF1 mRNA CTD PMID:16526316 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il10 interleukin 10 decreases secretion ISO Furosemide results in decreased secretion of IL10 protein CTD PMID:16612254 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il6 interleukin 6 decreases secretion ISO Furosemide results in decreased secretion of IL6 protein CTD PMID:16612254 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression EXP Furosemide results in decreased expression of ITGA5 mRNA CTD PMID:16526316 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Kdr kinase insert domain receptor increases expression EXP Furosemide results in increased expression of KDR mRNA CTD PMID:16526316 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lta lymphotoxin alpha affects expression EXP Furosemide affects the expression of LTA mRNA CTD PMID:17497460 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ltb lymphotoxin beta affects expression EXP Furosemide affects the expression of LTB mRNA CTD PMID:17497460 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Ltbr lymphotoxin beta receptor affects expression EXP Furosemide affects the expression of LTBR mRNA CTD PMID:17497460 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Mdk midkine increases expression EXP Furosemide results in increased expression of MDK mRNA CTD PMID:16526316 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mdm2 MDM2 proto-oncogene affects expression EXP Furosemide affects the expression of MDM2 mRNA CTD PMID:17497460 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Msr1 macrophage scavenger receptor 1 increases expression EXP Furosemide results in increased expression of MSR1 mRNA CTD PMID:16526316 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Furosemide results in increased expression of MT1 mRNA CTD PMID:24813929 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 affects expression EXP Furosemide affects the expression of NAIP2 mRNA CTD PMID:17497460 NCBI chr 2:31,507,423...31,559,098 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases localization
decreases response to substance
ISO Furosemide results in increased localization of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to Furosemide
CTD PMID:18078705 PMID:24813929 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein CTD PMID:29860548 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nol3 nucleolar protein 3 affects expression EXP Furosemide affects the expression of NOL3 mRNA CTD PMID:17497460 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Furosemide affects the expression of NOS3 mRNA CTD PMID:16526316 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A decreases expression ISO Furosemide results in decreased expression of NPPA protein CTD PMID:2146706 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of NQO1 mRNA CTD PMID:29860548 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha affects expression EXP Furosemide affects the expression of PDGFRA mRNA CTD PMID:16526316 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression EXP Furosemide results in increased expression of PDGFRB mRNA CTD PMID:16526316 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Furosemide results in increased expression of PECAM1 mRNA CTD PMID:16526316 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Furosemide results in decreased expression of PF4 mRNA CTD PMID:16526316 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Furosemide results in decreased activity of PGD protein CTD PMID:26820767 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgf placental growth factor decreases expression EXP Furosemide results in decreased expression of PGF mRNA CTD PMID:16526316 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions ISO PTGER4 protein affects the reaction [Furosemide results in increased expression of REN mRNA]; PTGER4 protein affects the reaction [Furosemide results in increased expression of REN protein] CTD PMID:15976003 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression EXP Furosemide affects the expression of PTGS1 mRNA; Furosemide affects the expression of PTGS1 protein CTD PMID:11961000 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions
increases expression
EXP Furosemide affects the expression of PTGS2 mRNA; Furosemide affects the expression of PTGS2 protein
[Furosemide results in increased expression of PTGS2 mRNA] which results in increased abundance of Prostaglandins; [rofecoxib results in decreased activity of PTGS2 protein] inhibits the reaction [Furosemide results in increased abundance of Prostaglandins]
Furosemide results in increased expression of PTGS2 mRNA; Furosemide results in increased expression of PTGS2 protein
CTD PMID:11135058 PMID:11703585 PMID:11961000 PMID:19031110 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth parathyroid hormone increases expression
multiple interactions
EXP Furosemide results in increased expression of PTH protein
NPS R-467 inhibits the reaction [Furosemide results in increased expression of PTH protein]
CTD PMID:15086907 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Ptn pleiotrophin affects expression EXP Furosemide affects the expression of PTN mRNA CTD PMID:16526316 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Ren renin multiple interactions
increases expression
increases secretion
increases activity
ISO
EXP
Furosemide inhibits the reaction [Ethinyl Estradiol results in increased expression of REN protein]; Indomethacin inhibits the reaction [Furosemide results in increased expression of REN protein]; Ketoprofen inhibits the reaction [Furosemide results in increased activity of REN protein]; Sulindac inhibits the reaction [Furosemide results in increased expression of REN protein]
Furosemide results in increased secretion of REN protein
Furosemide results in increased expression of REN mRNA; Furosemide results in increased expression of REN protein
PTGER4 protein affects the reaction [Furosemide results in increased expression of REN mRNA]; PTGER4 protein affects the reaction [Furosemide results in increased expression of REN protein]
CTD PMID:599795 PMID:1924052 PMID:3530574 PMID:4028619 PMID:7954537 More... NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 affects expression EXP Furosemide affects the expression of RIPK1 mRNA CTD PMID:17497460 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Rpa3 replication protein A3 affects expression EXP Furosemide affects the expression of RPA3 mRNA CTD PMID:17497460 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709
JBrowse link
G S100b S100 calcium binding protein B multiple interactions EXP [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]]; [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23880158 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G S100g S100 calcium binding protein G affects expression ISO Furosemide affects the expression of S100G mRNA CTD PMID:17652376 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression EXP Furosemide results in increased expression of S1PR1 mRNA CTD PMID:16526316 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Serpinb5 serpin family B member 5 increases expression EXP Furosemide results in increased expression of SERPINB5 mRNA CTD PMID:16526316 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinf1 serpin family F member 1 affects expression EXP Furosemide affects the expression of SERPINF1 mRNA CTD PMID:16526316 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases activity ISO Furosemide results in decreased activity of SLC12A1 protein CTD PMID:11249848 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions
decreases activity
EXP
ISO
[Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]]; [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein]; [Furosemide results in decreased activity of SLC12A2 protein] promotes the reaction [Thioctic Acid results in decreased activity of Ammonia]; [Furosemide results in decreased activity of SLC12A2 protein] which results in decreased susceptibility to Ammonia; [Furosemide results in decreased activity of SLC12A2 protein] which results in increased activity of Ammonia
Furosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]
CTD PMID:23880158 PMID:29959396 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc12a5 solute carrier family 12 member 5 decreases activity
multiple interactions
EXP
ISO
Furosemide results in decreased activity of SLC12A5 protein
Furosemide inhibits the reaction [SLC12A5 protein results in increased import of Thallium]
CTD PMID:18094240 PMID:20086212 NCBI chr 3:153,696,522...153,735,801
Ensembl chr 3:153,696,517...153,735,765
JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO Furosemide results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression
increases secretion
decreases activity
EXP
ISO
Furosemide results in increased expression of SLC22A6 protein
SLC22A6 protein results in increased secretion of Furosemide
Furosemide results in decreased activity of SLC22A6 protein
CTD PMID:12897087 PMID:18216144 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO Furosemide inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline] CTD PMID:15901346 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity
multiple interactions
increases secretion
ISO
EXP
Furosemide results in decreased activity of SLC22A8 protein
Furosemide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]
Furosemide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
SLC22A8 protein results in increased secretion of Furosemide
CTD PMID:10224140 PMID:11306713 PMID:18216144 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc26a4 solute carrier family 26 member 4 multiple interactions
affects localization
EXP [Furosemide co-treated with Amiloride] affects the localization of SLC26A4 protein
Furosemide affects the localization of SLC26A4 protein
CTD PMID:17311909 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression EXP Furosemide results in increased expression of SPARC mRNA CTD PMID:16526316 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP Furosemide results in increased expression of SPINK1 mRNA CTD PMID:28138970 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein; iodixanol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein]; Iohexol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] CTD PMID:29860548 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression EXP Furosemide results in increased expression of TEK mRNA CTD PMID:16526316 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Furosemide results in increased expression of TGFA mRNA CTD PMID:16526316 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression EXP Furosemide affects the expression of TGFB1 protein CTD PMID:18001696 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Furosemide results in increased expression of TGFB2 mRNA CTD PMID:16526316 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Furosemide results in increased expression of TGFBR1 mRNA CTD PMID:16526316 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP Furosemide results in increased expression of TGFBR2 mRNA CTD PMID:16526316 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thbs1 thrombospondin 1 affects expression EXP Furosemide affects the expression of THBS1 mRNA CTD PMID:16526316 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Furosemide results in increased expression of THBS2 mRNA CTD PMID:16526316 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Thbs3 thrombospondin 3 affects expression EXP Furosemide affects the expression of THBS3 mRNA CTD PMID:16526316 NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594
JBrowse link
G Thbs4 thrombospondin 4 affects expression EXP Furosemide affects the expression of THBS4 mRNA CTD PMID:16526316 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 increases expression EXP Furosemide results in increased expression of TIE1 mRNA CTD PMID:16526316 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 affects expression EXP Furosemide affects the expression of TIMP2 mRNA CTD PMID:16526316 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tnf tumor necrosis factor decreases secretion
affects expression
ISO
EXP
Furosemide results in decreased secretion of TNF protein
Furosemide affects the expression of TNF mRNA
CTD PMID:16526316 PMID:16612254 PMID:17497460 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A affects expression EXP Furosemide affects the expression of TNFRSF11A mRNA CTD PMID:17497460 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A affects expression EXP Furosemide affects the expression of TNFRSF1A mRNA CTD PMID:17497460 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B affects expression EXP Furosemide affects the expression of TNFRSF1B mRNA CTD PMID:17497460 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 affects expression EXP Furosemide affects the expression of TNFRSF25 mRNA CTD PMID:17497460 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 affects expression EXP Furosemide affects the expression of TNFRSF8 mRNA CTD PMID:17497460 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 affects expression EXP Furosemide affects the expression of TNFRSF9 mRNA CTD PMID:17497460 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 affects expression EXP Furosemide affects the expression of TNFSF10 mRNA CTD PMID:17497460 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf11 TNF superfamily member 11 affects expression EXP Furosemide affects the expression of TNFSF11 mRNA CTD PMID:17497460 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnfsf12 TNF superfamily member 12 affects expression EXP Furosemide affects the expression of TNFSF12 mRNA CTD PMID:17497460 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Tnfsf13 TNF superfamily member 13 affects expression EXP Furosemide affects the expression of TNFSF13 mRNA CTD PMID:17497460 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Tnfsf8 TNF superfamily member 8 affects expression EXP Furosemide affects the expression of TNFSF8 mRNA CTD PMID:17497460 NCBI chr 5:77,253,881...77,277,078
Ensembl chr 5:77,251,373...77,277,421
JBrowse link
G Tnfsf9 TNF superfamily member 9 affects expression EXP Furosemide affects the expression of TNFSF9 mRNA CTD PMID:17497460 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Tpmt thiopurine S-methyltransferase decreases activity ISO Furosemide results in decreased activity of TPMT protein CTD PMID:8866635 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709
JBrowse link
G Traf5 TNF receptor-associated factor 5 affects expression EXP Furosemide affects the expression of TRAF5 mRNA CTD PMID:17497460 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Traf6 TNF receptor associated factor 6 affects expression EXP Furosemide affects the expression of TRAF6 mRNA CTD PMID:17497460 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 increases expression ISO Furosemide results in increased expression of TRPV5 mRNA; Furosemide results in increased expression of TRPV5 protein CTD PMID:17652376 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases expression ISO Furosemide results in increased expression of TRPV6 mRNA CTD PMID:17652376 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Furosemide results in increased expression of UGT1A1 mRNA CTD PMID:18227147 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Furosemide CTD PMID:15117964 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Furosemide results in increased expression of VCAM1 mRNA CTD PMID:16526316 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression EXP Furosemide affects the expression of VEGFA mRNA CTD PMID:16526316 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C increases expression EXP Furosemide results in increased expression of VEGFC mRNA CTD PMID:16526316 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Xiap X-linked inhibitor of apoptosis affects expression EXP Furosemide affects the expression of XIAP mRNA CTD PMID:17497460 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          furosemide 168
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        aromatic carboxylic acid 11710
                                          benzoic acids 11683
                                            chlorobenzoic acid 168
                                              furosemide 168
paths to the root