CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Abcb10
ATP binding cassette subfamily B member 10
decreases expression
ISO
cupric oxide results in decreased expression of ABCB10 mRNA
CTD
PMID:22077320
NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753
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Abcf1
ATP binding cassette subfamily F member 1
decreases expression
ISO
cupric oxide results in decreased expression of ABCF1 protein
CTD
PMID:25470785
NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
ISO
cupric oxide results in increased expression of ACSL3 protein
CTD
PMID:25470785
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acsl4
acyl-CoA synthetase long-chain family member 4
decreases expression
ISO
cupric oxide results in decreased expression of ACSL4 protein
CTD
PMID:25470785
NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Actn4
actinin alpha 4
increases expression
ISO
cupric oxide results in increased expression of ACTN4 protein
CTD
PMID:25470785
NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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Actr3b
actin related protein 3B
decreases expression
ISO
cupric oxide results in decreased expression of ACTR3B mRNA
CTD
PMID:22077320
NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
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Aff1
ALF transcription elongation factor 1
increases expression
ISO
cupric oxide results in increased expression of AFF1 mRNA
CTD
PMID:22077320
NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729
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Ahcy
adenosylhomocysteinase
decreases expression
ISO
cupric oxide results in decreased expression of AHCY protein
CTD
PMID:25470785
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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Ahnak
AHNAK nucleoprotein
decreases expression decreases phosphorylation
ISO
cupric oxide results in decreased expression of AHNAK protein cupric oxide results in decreased phosphorylation of AHNAK protein
CTD
PMID:25470785
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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Ahsa1
activator of Hsp90 ATPase activity 1
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of AHSA1 protein
CTD
PMID:25470785
NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
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Ajuba
ajuba LIM protein
decreases expression
ISO
cupric oxide results in decreased expression of AJUBA mRNA
CTD
PMID:22077320
NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
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Akt1s1
AKT1 substrate 1
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of AKT1S1 protein
CTD
PMID:25470785
NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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Alb
albumin
multiple interactions decreases expression
EXP
[cupric oxide co-treated with lead oxide co-treated with Zinc Oxide] results in decreased expression of ALB protein cupric oxide results in decreased expression of ALB protein
CTD
PMID:28212817
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
decreases expression
ISO
cupric oxide results in decreased expression of ALDH1A1 mRNA
CTD
PMID:32285662
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldoa
aldolase, fructose-bisphosphate A
decreases expression
ISO
cupric oxide results in decreased expression of ALDOA protein
CTD
PMID:25470785
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Aldoc
aldolase, fructose-bisphosphate C
decreases expression
ISO
cupric oxide results in decreased expression of ALDOC protein
CTD
PMID:25470785
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of ALG14 protein
CTD
PMID:25470785
NCBI chr 2:209,368,285...209,445,425
Ensembl chr 2:209,368,312...209,445,431
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Alpk2
alpha-kinase 2
decreases expression
ISO
cupric oxide results in decreased expression of ALPK2 mRNA
CTD
PMID:22077320
NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
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Als2
alsin Rho guanine nucleotide exchange factor ALS2
increases expression
ISO
cupric oxide results in increased expression of ALS2 mRNA
CTD
PMID:22077320
NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
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Angptl4
angiopoietin-like 4
decreases expression
ISO
cupric oxide results in decreased expression of ANGPTL4 mRNA
CTD
PMID:22077320
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Anxa2
annexin A2
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of ANXA2 protein
CTD
PMID:25470785
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Arc
activity-regulated cytoskeleton-associated protein
increases expression
ISO
cupric oxide results in increased expression of ARC mRNA
CTD
PMID:22077320
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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Areg
amphiregulin
decreases expression
ISO
cupric oxide results in decreased expression of AREG mRNA
CTD
PMID:22077320
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Arf3
ADP-ribosylation factor 3
decreases expression
ISO
cupric oxide results in decreased expression of ARF3 protein
CTD
PMID:25470785
NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
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Arhgdia
Rho GDP dissociation inhibitor alpha
decreases expression
ISO
cupric oxide analog results in decreased expression of ARHGDIA protein
CTD
PMID:23882024
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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Arhgdib
Rho GDP dissociation inhibitor beta
decreases expression
ISO
cupric oxide analog results in decreased expression of ARHGDIB protein
CTD
PMID:23882024
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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Asns
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
cupric oxide results in increased expression of ASNS mRNA
CTD
PMID:22077320
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Atf1
activating transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of ATF1 mRNA
CTD
PMID:22077320
NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
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Atf3
activating transcription factor 3
increases expression
ISO
cupric oxide results in increased expression of ATF3 mRNA
CTD
PMID:22077320
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atp6v1a
ATPase H+ transporting V1 subunit A
increases expression
ISO
cupric oxide results in increased expression of ATP6V1A mRNA
CTD
PMID:22077320
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Atp6v1b2
ATPase H+ transporting V1 subunit B2
increases expression
ISO
cupric oxide results in increased expression of ATP6V1B2 mRNA
CTD
PMID:22077320
NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
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Atp6v1c1
ATPase H+ transporting V1 subunit C1
increases expression
ISO
cupric oxide results in increased expression of ATP6V1C1 mRNA
CTD
PMID:22077320
NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
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Atp6v1d
ATPase H+ transporting V1 subunit D
increases expression
ISO
cupric oxide results in increased expression of ATP6V1D mRNA
CTD
PMID:22077320
NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303
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Atp6v1g1
ATPase H+ transporting V1 subunit G1
increases expression
ISO
cupric oxide results in increased expression of ATP6V1G1 mRNA
CTD
PMID:22077320
NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
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Atp6v1h
ATPase H+ transporting V1 subunit H
increases expression decreases expression
ISO
cupric oxide results in increased expression of ATP6V1H mRNA cupric oxide analog results in decreased expression of ATP6V1H protein
CTD
PMID:22077320 PMID:23882024
NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
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Atp7a
ATPase copper transporting alpha
increases expression
ISO
cupric oxide analog results in increased expression of ATP7A mRNA; cupric oxide analog results in increased expression of ATP7A protein
CTD
PMID:24815816
NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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Atp7b
ATPase copper transporting beta
affects localization increases expression
ISO
cupric oxide affects the localization of ATP7B protein cupric oxide analog results in increased expression of ATP7B mRNA; cupric oxide analog results in increased expression of ATP7B protein
CTD
PMID:24343273 PMID:24815816
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Atr
ATR serine/threonine kinase
decreases expression
ISO
cupric oxide results in decreased expression of ATR mRNA
CTD
PMID:22077320
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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Atrx
ATRX, chromatin remodeler
decreases expression
ISO
cupric oxide results in decreased expression of ATRX mRNA
CTD
PMID:22077320
NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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Aurka
aurora kinase A
decreases expression
ISO
cupric oxide results in decreased expression of AURKA mRNA
CTD
PMID:22077320
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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Aurkb
aurora kinase B
decreases expression
ISO
cupric oxide results in decreased expression of AURKB mRNA
CTD
PMID:22077320
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Axin2
axin 2
decreases expression
ISO
cupric oxide results in decreased expression of AXIN2 mRNA
CTD
PMID:32285662
NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
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Axl
Axl receptor tyrosine kinase
decreases expression
ISO
cupric oxide results in decreased expression of AXL mRNA
CTD
PMID:22077320
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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Banf1
BAF nuclear assembly factor 1
decreases expression
ISO
cupric oxide results in decreased expression of BANF1 protein
CTD
PMID:25470785
NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188
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Bard1
BRCA1 associated RING domain 1
decreases expression
ISO
cupric oxide results in decreased expression of BARD1 mRNA
CTD
PMID:22077320
NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
trans-sodium crocetinate inhibits the reaction [cupric oxide results in increased expression of BAX mRNA]
CTD
PMID:25701151
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbc3
Bcl-2 binding component 3
decreases expression
ISO
cupric oxide results in decreased expression of BBC3 mRNA
CTD
PMID:32285662
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Bcar3
BCAR3 adaptor protein, NSP family member
decreases expression
ISO
cupric oxide results in decreased expression of BCAR3 mRNA
CTD
PMID:22077320
NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
ISO
trans-sodium crocetinate inhibits the reaction [cupric oxide results in decreased expression of BCL2 mRNA]
CTD
PMID:25701151 PMID:32285662
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2a1
BCL2-related protein A1
decreases expression
ISO
cupric oxide results in decreased expression of BCL2A1 mRNA
CTD
PMID:22077320
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
cupric oxide results in decreased expression of BCL2L1 mRNA
CTD
PMID:32285662
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bex1
brain expressed X-linked 1
increases expression
ISO
cupric oxide results in increased expression of BEX2 mRNA
CTD
PMID:22077320
NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958
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Bloc1s1
biogenesis of lysosomal organelles complex-1, subunit 1
increases expression
ISO
cupric oxide results in increased expression of BLOC1S1 mRNA
CTD
PMID:22077320
NCBI chr 7:1,347,495...1,351,103
Ensembl chr 7:1,340,934...1,351,558
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Bnip3l
BCL2 interacting protein 3 like
increases expression
ISO
cupric oxide results in increased expression of BNIP3L mRNA
CTD
PMID:22077320
NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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Brca2
BRCA2, DNA repair associated
increases expression
ISO
cupric oxide results in increased expression of BRCA2 mRNA
CTD
PMID:32285662
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Brf2
BRF2, RNA polymerase III transcription initiation factor subunit
increases expression
ISO
cupric oxide results in increased expression of BRF2 mRNA
CTD
PMID:22077320
NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059
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Bsg
basigin
decreases expression
ISO
cupric oxide results in decreased expression of BSG protein
CTD
PMID:25470785
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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C10h5orf58
similar to human chromosome 5 open reading frame 58
increases expression
ISO
cupric oxide results in increased expression of C5ORF58 mRNA
CTD
PMID:22077320
NCBI chr10:18,690,958...18,697,224
Ensembl chr10:18,688,847...18,697,220
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C1qbp
complement C1q binding protein
decreases expression
ISO
cupric oxide results in decreased expression of C1QBP protein
CTD
PMID:25470785
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
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C1s
complement C1s
increases expression
ISO
cupric oxide results in increased expression of C1S mRNA
CTD
PMID:22077320
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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Calm1
calmodulin 1
increases expression
ISO
cupric oxide results in increased expression of CALM1 protein
CTD
PMID:25470785
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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Calr
calreticulin
decreases expression
ISO
cupric oxide results in decreased expression of CALR protein
CTD
PMID:25470785
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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Calu
calumenin
increases expression
ISO
cupric oxide results in increased expression of CALU protein
CTD
PMID:25470785
NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
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Cap1
cyclase associated actin cytoskeleton regulatory protein 1
decreases expression
ISO
cupric oxide results in decreased expression of CAP1 protein
CTD
PMID:25470785
NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
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Capzb
capping actin protein of muscle Z-line subunit beta
increases expression
ISO
cupric oxide results in increased expression of CAPZB protein
CTD
PMID:25470785
NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
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Card6
caspase recruitment domain family, member 6
increases expression
ISO
cupric oxide results in increased expression of CARD6 mRNA
CTD
PMID:22077320
NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846
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Casp3
caspase 3
decreases activity
ISO
cupric oxide results in decreased activity of CASP3 protein
CTD
PMID:22954531
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
decreases activity multiple interactions decreases expression
ISO EXP
cupric oxide results in decreased activity of CAT protein CAT protein inhibits the reaction [cupric oxide results in increased abundance of Reactive Oxygen Species] cupric oxide analog results in decreased expression of CAT protein costus absolute inhibits the reaction [cupric oxide analog results in decreased expression of CAT protein]
CTD
PMID:19699289 PMID:20171267 PMID:36286243
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccdc80
coiled-coil domain containing 80
decreases expression
ISO
cupric oxide results in decreased expression of CCDC80 mRNA
CTD
PMID:22077320
NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137
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Ccl2
C-C motif chemokine ligand 2
increases secretion affects expression
ISO
cupric oxide results in increased secretion of CCL2 protein cupric oxide affects the expression of CCL2 mRNA
CTD
PMID:28705761
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccna2
cyclin A2
decreases expression
ISO
cupric oxide results in decreased expression of CCNA2 mRNA
CTD
PMID:22077320
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
cupric oxide results in decreased expression of CCNB1 mRNA
CTD
PMID:22077320
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnb2
cyclin B2
decreases expression
ISO
cupric oxide results in decreased expression of CCNB2 mRNA
CTD
PMID:22077320
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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Ccnk
cyclin K
increases expression
ISO
cupric oxide results in increased expression of CCNK mRNA
CTD
PMID:22077320
NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
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Cct3
chaperonin containing TCP1 subunit 3
decreases expression
ISO
cupric oxide results in decreased expression of CCT3 protein
CTD
PMID:25470785
NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
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Cct5
chaperonin containing TCP1 subunit 5
increases expression
ISO
cupric oxide results in increased expression of CCT5 protein
CTD
PMID:25470785
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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Cct6a
chaperonin containing TCP1 subunit 6A
increases expression
ISO
cupric oxide results in increased expression of CCT6A protein
CTD
PMID:25470785
NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
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Cct8
chaperonin containing TCP1 subunit 8
increases expression
ISO
cupric oxide results in increased expression of CCT8 protein
CTD
PMID:25470785
NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
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Cdc20
cell division cycle 20
decreases expression
ISO
cupric oxide results in decreased expression of CDC20 mRNA
CTD
PMID:22077320
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc40
cell division cycle 40
increases expression
ISO
cupric oxide results in increased expression of CDC40 mRNA
CTD
PMID:22077320
NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358
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Cdc42
cell division cycle 42
decreases expression
ISO
cupric oxide results in decreased expression of CDC42 protein
CTD
PMID:25470785
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdca3
cell division cycle associated 3
decreases expression
ISO
cupric oxide results in decreased expression of CDCA3 mRNA
CTD
PMID:22077320
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
cupric oxide results in decreased expression of CDK1 mRNA
CTD
PMID:22077320
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk5r2
cyclin-dependent kinase 5 regulatory subunit 2
increases expression
ISO
cupric oxide results in increased expression of CDK5R2 mRNA
CTD
PMID:22077320
NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344
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Cdk6
cyclin-dependent kinase 6
decreases expression
ISO
cupric oxide results in decreased expression of CDK6 mRNA
CTD
PMID:22077320
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdkl3
cyclin-dependent kinase-like 3
increases expression
ISO
cupric oxide results in increased expression of CDKL3 mRNA
CTD
PMID:22077320
NCBI chr10:36,263,212...36,349,268
Ensembl chr10:36,266,977...36,349,268
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
cupric oxide results in increased expression of CDKN1A mRNA
CTD
PMID:32285662
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
decreases expression
ISO
cupric oxide results in decreased expression of CDKN1B mRNA
CTD
PMID:22077320 PMID:32285662
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cdkn2aip
CDKN2A interacting protein
increases expression
ISO
cupric oxide results in increased expression of CDKN2AIP mRNA
CTD
PMID:22077320
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
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Cdkn2c
cyclin-dependent kinase inhibitor 2C
decreases expression
ISO
cupric oxide results in decreased expression of CDKN2C mRNA
CTD
PMID:22077320
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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Cebpg
CCAAT/enhancer binding protein gamma
increases expression
ISO
cupric oxide results in increased expression of CEBPG mRNA
CTD
PMID:22077320
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
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Celf1
CUGBP, Elav-like family member 1
increases expression
ISO
cupric oxide results in increased expression of CELF1 mRNA
CTD
PMID:22077320
NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
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Cenpa
centromere protein A
decreases expression
ISO
cupric oxide results in decreased expression of CENPA mRNA
CTD
PMID:22077320
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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Cfl1
cofilin 1
increases expression
ISO
cupric oxide results in increased expression of CFL1 protein
CTD
PMID:25470785
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Champ1
chromosome alignment maintaining phosphoprotein 1
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of CHAMP1 protein
CTD
PMID:25470785
NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984
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Cit
citron rho-interacting serine/threonine kinase
decreases expression
ISO
cupric oxide results in decreased expression of CIT mRNA
CTD
PMID:22077320
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
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Ckap2
cytoskeleton associated protein 2
decreases expression
ISO
cupric oxide results in decreased expression of CKAP2 mRNA
CTD
PMID:22077320
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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Ckap5
cytoskeleton associated protein 5
decreases expression
ISO
cupric oxide results in decreased expression of CKAP5 mRNA
CTD
PMID:22077320
NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
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Ckb
creatine kinase B
multiple interactions
EXP
costus absolute inhibits the reaction [cupric oxide analog results in increased secretion of [CKM protein binds to CKB protein]]; cupric oxide analog results in increased secretion of [CKM protein binds to CKB protein]
CTD
PMID:36286243
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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Ckm
creatine kinase, M-type
multiple interactions
EXP
costus absolute inhibits the reaction [cupric oxide analog results in increased secretion of [CKM protein binds to CKB protein]]; cupric oxide analog results in increased secretion of [CKM protein binds to CKB protein]
CTD
PMID:36286243
NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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Clcn6
chloride voltage-gated channel 6
increases expression
ISO
cupric oxide results in increased expression of CLCN6 mRNA
CTD
PMID:22077320
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
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Cldn23
claudin 23
decreases expression
ISO
cupric oxide results in decreased expression of CLDN23 mRNA
CTD
PMID:22077320
NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
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Clic1
chloride intracellular channel 1
decreases expression
ISO
cupric oxide analog results in decreased expression of CLIC1 protein
CTD
PMID:23882024
NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
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Clk1
CDC-like kinase 1
increases expression
ISO
cupric oxide results in increased expression of CLK1 mRNA
CTD
PMID:22077320
NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
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Clu
clusterin
increases expression
ISO
cupric oxide results in increased expression of CLU mRNA
CTD
PMID:22077320
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cnn3
calponin 3
increases expression
ISO
cupric oxide results in increased expression of CNN3 protein
CTD
PMID:25470785
NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
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Coch
cochlin
decreases expression
ISO
cupric oxide results in decreased expression of COCH mRNA
CTD
PMID:22077320
NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
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Col4a1
collagen type IV alpha 1 chain
decreases expression
ISO
cupric oxide results in decreased expression of COL4A1 mRNA
CTD
PMID:22077320
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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Col5a1
collagen type V alpha 1 chain
decreases expression
ISO
cupric oxide results in decreased expression of COL5A1 mRNA
CTD
PMID:22077320
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
decreases expression
ISO
cupric oxide results in decreased expression of COL5A2 mRNA
CTD
PMID:22077320
NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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Cpeb4
cytoplasmic polyadenylation element binding protein 4
increases expression
ISO
cupric oxide results in increased expression of CPEB4 mRNA
CTD
PMID:22077320
NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
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Crem
cAMP responsive element modulator
increases expression
ISO
cupric oxide results in increased expression of CREM mRNA
CTD
PMID:22077320
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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Cript
CXXC repeat containing interactor of PDZ3 domain
increases expression
ISO
cupric oxide results in increased expression of CRIPT mRNA
CTD
PMID:22077320
NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399
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Cryab
crystallin, alpha B
increases expression
ISO
cupric oxide results in increased expression of CRYAB mRNA
CTD
PMID:22077320
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Crybg1
crystallin beta-gamma domain containing 1
increases expression
ISO
cupric oxide results in increased expression of CRYBG1 protein
CTD
PMID:25470785
NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392
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Csta
cystatin A
increases expression
ISO
cupric oxide results in increased expression of CSTA mRNA
CTD
PMID:22077320
NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
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Cyb5r2
cytochrome b5 reductase 2
increases expression
ISO
cupric oxide results in increased expression of CYB5R2 mRNA
CTD
PMID:22077320
NCBI chr 1:161,655,862...161,664,359
Ensembl chr 1:161,655,864...161,664,097
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Dapk1
death associated protein kinase 1
decreases expression
ISO
cupric oxide results in decreased expression of DAPK1 mRNA
CTD
PMID:22077320
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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Dbf4
DBF4-CDC7 kinase regulatory subunit
decreases expression
ISO
cupric oxide results in decreased expression of DBF4 mRNA
CTD
PMID:22077320
NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
cupric oxide results in increased expression of DDIT3 mRNA
CTD
PMID:32285662
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx5
DEAD-box helicase 5
increases expression
ISO
cupric oxide results in increased expression of DDX5 protein
CTD
PMID:25470785
NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
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Dhrs2
dehydrogenase/reductase 2
increases expression
ISO
cupric oxide results in increased expression of DHRS2 mRNA
CTD
PMID:22077320
NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
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Dhx58
DEXH-box helicase 58
increases expression
ISO
cupric oxide results in increased expression of DHX58 mRNA
CTD
PMID:22077320
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
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Dis3l
DIS3-like exosome 3'-5' exoribonuclease
decreases expression
ISO
cupric oxide results in decreased expression of DIS3L mRNA
CTD
PMID:22077320
NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165
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Dlc1
DLC1 Rho GTPase activating protein
decreases expression
ISO
cupric oxide results in decreased expression of DLC1 mRNA
CTD
PMID:22077320
NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
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Dlg5
discs large MAGUK scaffold protein 5
decreases expression
ISO
cupric oxide results in decreased expression of DLG5 mRNA
CTD
PMID:22077320
NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
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Dlgap5
DLG associated protein 5
decreases expression
ISO
cupric oxide results in decreased expression of DLGAP5 mRNA
CTD
PMID:22077320
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
increases expression
ISO
cupric oxide results in increased expression of DNAJA1 mRNA
CTD
PMID:22077320
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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Dnaja4
DnaJ heat shock protein family (Hsp40) member A4
increases expression
ISO
cupric oxide results in increased expression of DNAJA4 mRNA
CTD
PMID:22077320
NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
G
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
increases expression
ISO
cupric oxide results in increased expression of DNAJB1 mRNA
CTD
PMID:22077320
NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
G
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
increases expression
ISO
cupric oxide results in increased expression of DNAJB6 mRNA
CTD
PMID:22077320
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
G
Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
increases expression
ISO
cupric oxide results in increased expression of DNAJB9 mRNA
CTD
PMID:22077320
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
G
Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
increases expression
ISO
cupric oxide results in increased expression of DNAJC3 mRNA
CTD
PMID:22077320
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
G
Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
decreases expression
ISO
cupric oxide results in decreased expression of DNAJC5 mRNA
CTD
PMID:22077320
NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
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Dst
dystonin
decreases expression
ISO
cupric oxide results in decreased expression of DST mRNA
CTD
PMID:22077320
NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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E2f1
E2F transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of E2F1 mRNA
CTD
PMID:32285662
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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E2f6
E2F transcription factor 6
increases expression
ISO
cupric oxide results in increased expression of E2F6 mRNA
CTD
PMID:22077320
NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683
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E2f7
E2F transcription factor 7
decreases expression
ISO
cupric oxide results in decreased expression of E2F7 mRNA
CTD
PMID:22077320
NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
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E2f8
E2F transcription factor 8
decreases expression
ISO
cupric oxide results in decreased expression of E2F8 mRNA
CTD
PMID:22077320
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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Echs1
enoyl-CoA hydratase, short chain 1
decreases expression
ISO
cupric oxide results in decreased expression of ECHS1 protein
CTD
PMID:25470785
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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Eef1b2
eukaryotic translation elongation factor 1 beta 2
decreases expression increases expression
ISO
cupric oxide analog results in decreased expression of EEF1B2 protein cupric oxide results in increased expression of EEF1B2 protein
CTD
PMID:23882024 PMID:25470785
NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737
G
Eef1d
eukaryotic translation elongation factor 1 delta
decreases expression
ISO
cupric oxide analog results in decreased expression of EEF1D protein
CTD
PMID:23882024
NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
G
Efemp1
EGF containing fibulin extracellular matrix protein 1
decreases expression
ISO
cupric oxide results in decreased expression of EFEMP1 mRNA
CTD
PMID:22077320
NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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Efhb
EF hand domain family, member B
decreases expression
ISO
cupric oxide results in decreased expression of EFHB mRNA
CTD
PMID:22077320
NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919
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Egr1
early growth response 1
increases expression
ISO
cupric oxide results in increased expression of EGR1 mRNA
CTD
PMID:22077320
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Ehmt1
euchromatic histone lysine methyltransferase 1
decreases expression
ISO
cupric oxide results in decreased expression of EHMT1 mRNA
CTD
PMID:22077320
NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
G
Eif2ak4
eukaryotic translation initiation factor 2 alpha kinase 4
decreases expression
ISO
cupric oxide results in decreased expression of EIF2AK4 mRNA
CTD
PMID:22077320
NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
G
Eif3b
eukaryotic translation initiation factor 3, subunit B
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of EIF3B protein
CTD
PMID:25470785
NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
G
Eif3f
eukaryotic translation initiation factor 3, subunit F
decreases expression
ISO
cupric oxide results in decreased expression of EIF3F protein
CTD
PMID:25470785
NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
G
Eif3g
eukaryotic translation initiation factor 3, subunit G
affects phosphorylation
ISO
cupric oxide affects the phosphorylation of EIF3G protein
CTD
PMID:25470785
NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
G
Eif3l
eukaryotic translation initiation factor 3, subunit L
increases expression
ISO
cupric oxide results in increased expression of EIF3L protein
CTD
PMID:25470785
NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
G
Eif4h
eukaryotic translation initiation factor 4H
increases expression
ISO
cupric oxide results in increased expression of EIF4H protein
CTD
PMID:25470785
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
G
Eif5a
eukaryotic translation initiation factor 5A
decreases expression
ISO
cupric oxide analog results in decreased expression of EIF5A protein
CTD
PMID:23882024
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
G
Eif5b
eukaryotic translation initiation factor 5B
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of EIF5B protein
CTD
PMID:25470785
NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
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Ell
elongation factor for RNA polymerase II
increases expression
ISO
cupric oxide results in increased expression of ELL mRNA
CTD
PMID:22077320
NCBI chr16:18,843,775...18,891,484
Ensembl chr16:18,843,780...18,891,118
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Ephb2
Eph receptor B2
decreases expression
ISO
cupric oxide results in decreased expression of EPHB2 mRNA
CTD
PMID:22077320
NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
G
Ephx1
epoxide hydrolase 1
decreases expression
ISO
cupric oxide results in decreased expression of EPHX1 mRNA
CTD
PMID:32285662
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Erbb2
erb-b2 receptor tyrosine kinase 2
decreases expression
ISO
cupric oxide results in decreased expression of ERBB2 mRNA
CTD
PMID:22077320
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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Erp29
endoplasmic reticulum protein 29
increases expression
ISO
cupric oxide analog results in increased expression of ERP29 protein
CTD
PMID:23882024
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Esd
esterase D
increases expression
ISO
cupric oxide analog results in increased expression of ESD protein
CTD
PMID:23882024
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
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Evi5
ecotropic viral integration site 5
decreases expression
ISO
cupric oxide results in decreased expression of EVI5 mRNA
CTD
PMID:22077320
NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
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Ezr
ezrin
decreases expression
ISO
cupric oxide results in decreased expression of EZR protein
CTD
PMID:25470785
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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Fam241b
family with sequence similarity 241 member B
increases expression
ISO
cupric oxide results in increased expression of FAM241B mRNA
CTD
PMID:22077320
NCBI chr20:30,052,315...30,055,247
Ensembl chr20:30,052,324...30,055,084
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Fam83d
family with sequence similarity 83, member D
decreases expression
ISO
cupric oxide results in decreased expression of FAM83D mRNA
CTD
PMID:22077320
NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
G
Fbxl19
F-box and leucine-rich repeat protein 19
increases expression
ISO
cupric oxide results in increased expression of FBXL19 mRNA
CTD
PMID:22077320
NCBI chr 1:182,356,899...182,380,839
Ensembl chr 1:182,360,830...182,380,083
G
Fbxl4
F-box and leucine-rich repeat protein 4
decreases expression
ISO
cupric oxide results in decreased expression of FBXL4 mRNA
CTD
PMID:22077320
NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
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Fbxo5
F-box protein 5
decreases expression
ISO
cupric oxide results in decreased expression of FBXO5 mRNA
CTD
PMID:22077320
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
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Fdps
farnesyl diphosphate synthase
decreases expression
ISO
cupric oxide analog results in decreased expression of FDPS protein
CTD
PMID:23882024
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
G
Fkbp7
FKBP prolyl isomerase 7
decreases expression
ISO
cupric oxide results in decreased expression of FKBP7 mRNA
CTD
PMID:22077320
NCBI chr 3:61,609,384...61,623,710
Ensembl chr 3:61,608,557...61,623,280
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
cupric oxide results in increased expression of FOS mRNA
CTD
PMID:22077320
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
cupric oxide results in increased expression of FOSB mRNA
CTD
PMID:22077320
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
G
Foxf2
forkhead box F2
decreases expression
ISO
cupric oxide results in decreased expression of FOXF2 mRNA
CTD
PMID:22077320
NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176
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Foxn3
forkhead box N3
increases expression
ISO
cupric oxide results in increased expression of FOXN3 mRNA
CTD
PMID:22077320
NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401
G
Fsd1l
fibronectin type III and SPRY domain containing 1-like
increases expression
ISO
cupric oxide results in increased expression of FSD1L mRNA
CTD
PMID:22077320
NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928
G
Fshb
follicle stimulating hormone subunit beta
increases expression
EXP
cupric oxide results in increased expression of FSHB protein
CTD
PMID:28212817
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G0s2
G0/G1switch 2
decreases expression
ISO
cupric oxide results in decreased expression of G0S2 mRNA
CTD
PMID:22077320
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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Gabarapl1
GABA type A receptor associated protein like 1
increases expression
ISO
cupric oxide results in increased expression of GABARAPL1 mRNA
CTD
PMID:22077320
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
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Gabpa
GA binding protein transcription factor subunit alpha
increases expression
ISO
cupric oxide results in increased expression of GABPA mRNA
CTD
PMID:22077320
NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
cupric oxide results in increased expression of GADD45A mRNA
CTD
PMID:32285662
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression decreases response to substance
ISO
cupric oxide results in increased expression of GADD45B mRNA; cupric oxide results in increased expression of GADD45B protein GADD45B protein results in decreased susceptibility to cupric oxide
CTD
PMID:22077320
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
cupric oxide results in increased expression of GADD45G mRNA; cupric oxide results in increased expression of GADD45G protein
CTD
PMID:22077320
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
G
Galk1
galactokinase 1
decreases expression
ISO
cupric oxide analog results in decreased expression of GALK1 protein
CTD
PMID:23882024
NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
G
Gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of GBF1 protein
CTD
PMID:25470785
NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
cupric oxide analog results in increased expression of GCLM protein cupric oxide results in increased expression of GCLM mRNA
CTD
PMID:23882024 PMID:24343273
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdf15
growth differentiation factor 15
increases expression
ISO
cupric oxide results in increased expression of GDF15 mRNA
CTD
PMID:22077320
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gem
GTP binding protein overexpressed in skeletal muscle
increases expression
ISO
cupric oxide results in increased expression of GEM mRNA
CTD
PMID:22077320
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
G
Gemin5
gem (nuclear organelle) associated protein 5
decreases expression
ISO
cupric oxide results in decreased expression of GEMIN5 mRNA
CTD
PMID:22077320
NCBI chr10:42,295,729...42,342,902
Ensembl chr10:42,297,515...42,342,892
G
Ggt1
gamma-glutamyltransferase 1
multiple interactions
EXP
[cupric oxide co-treated with lead oxide co-treated with Zinc Oxide] results in increased activity of GGT1 protein; [cupric oxide co-treated with lead oxide] results in increased activity of GGT1 protein
CTD
PMID:28212817
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
G
Glo1
glyoxalase 1
decreases expression
ISO
cupric oxide results in decreased expression of GLO1 protein
CTD
PMID:25470785
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
G
Glud1
glutamate dehydrogenase 1
increases expression
ISO
cupric oxide analog results in increased expression of GLUD1 protein
CTD
PMID:23882024
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
cupric oxide analog results in decreased expression of GNAI2 protein
CTD
PMID:23882024
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
G
Gpsm2
G-protein signaling modulator 2
decreases expression
ISO
cupric oxide results in decreased expression of GPSM2 mRNA
CTD
PMID:22077320
NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154
G
Gpx1
glutathione peroxidase 1
multiple interactions decreases expression
ISO
trans-sodium crocetinate inhibits the reaction [cupric oxide results in decreased expression of GPX1 mRNA]
CTD
PMID:25701151
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx2
glutathione peroxidase 2
decreases expression
ISO
cupric oxide results in decreased expression of GPX2 mRNA
CTD
PMID:32285662
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx4
glutathione peroxidase 4
decreases expression multiple interactions
ISO
cupric oxide results in decreased expression of GPX4 mRNA trans-sodium crocetinate inhibits the reaction [cupric oxide results in decreased expression of GPX4 mRNA]
CTD
PMID:25701151
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grn
granulin precursor
increases expression
ISO
cupric oxide results in increased expression of GRN mRNA
CTD
PMID:22077320
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
G
Gsr
glutathione-disulfide reductase
decreases activity
ISO EXP
cupric oxide results in decreased activity of GSR protein
CTD
PMID:19699289 PMID:20600438
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gtf2b
general transcription factor IIB
increases expression
ISO
cupric oxide results in increased expression of GTF2B mRNA
CTD
PMID:22077320
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
G
Gtse1
G-2 and S-phase expressed 1
decreases expression
ISO
cupric oxide results in decreased expression of GTSE1 mRNA
CTD
PMID:22077320
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
G
H1f10
H1.10 linker histone
decreases expression
ISO
cupric oxide results in decreased expression of H1-10 mRNA
CTD
PMID:22077320
NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448
G
H2ac21
H2A clustered histone 21
increases expression
ISO
cupric oxide results in increased expression of H2AC21 mRNA
CTD
PMID:22077320
NCBI chr 2:183,779,355...183,779,788
G
H2ax
H2A.X variant histone
increases expression decreases expression
ISO
cupric oxide analog results in increased expression of H2AX protein cupric oxide results in decreased expression of H2AX mRNA
CTD
PMID:22077320 PMID:27270449
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
G
Hbp1
HMG-box transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of HBP1 mRNA
CTD
PMID:22077320
NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
G
Hdac1
histone deacetylase 1
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of HDAC1 protein
CTD
PMID:25470785
NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
G
Hdgf
heparin binding growth factor
increases expression
ISO
cupric oxide results in increased expression of HDGF protein
CTD
PMID:25470785
NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
G
Hes1
hes family bHLH transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of HES1 mRNA
CTD
PMID:22077320
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
G
Hey1
hes-related family bHLH transcription factor with YRPW motif 1
increases expression
ISO
cupric oxide results in increased expression of HEY1 mRNA
CTD
PMID:22077320
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
G
Hint3
histidine triad nucleotide binding protein 3
increases expression
ISO
cupric oxide results in increased expression of HINT3 mRNA
CTD
PMID:22077320
NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721
G
Hmgb2
high mobility group box 2
decreases expression
ISO
cupric oxide results in decreased expression of HMGB2 mRNA
CTD
PMID:22077320
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
[Buthionine Sulfoximine co-treated with Dehydroascorbic Acid] promotes the reaction [cupric oxide results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [cupric oxide results in increased expression of HMOX1 mRNA]; Dehydroascorbic Acid promotes the reaction [cupric oxide results in increased expression of HMOX1 mRNA] cupric oxide results in increased expression of HMOX1 mRNA; cupric oxide results in increased expression of HMOX1 protein cupric oxide analog results in increased expression of HMOX1 protein
CTD
PMID:19683516 PMID:23882024 PMID:24343273 PMID:32285662 PMID:33839236
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
increases expression
ISO
cupric oxide results in increased expression of HNRNPH2 mRNA
CTD
PMID:22077320
NCBI chr X:97,780,890...97,786,846
Ensembl chr X:97,780,785...97,787,041
G
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of HNRNPK protein
CTD
PMID:25470785
NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
G
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
decreases expression
ISO
cupric oxide results in decreased expression of HNRNPL protein
CTD
PMID:25470785
NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553
G
Hrh1
histamine receptor H 1
increases expression
ISO
cupric oxide results in increased expression of HRH1 mRNA
CTD
PMID:22077320
NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
G
Hsf2
heat shock transcription factor 2
increases expression
ISO
cupric oxide results in increased expression of HSF2 mRNA
CTD
PMID:22077320
NCBI chr20:36,819,864...36,847,490
Ensembl chr20:36,819,864...36,850,174
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
cupric oxide results in increased expression of HSP90AA1 mRNA
CTD
PMID:22077320
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa13
heat shock protein family A (Hsp70) member 13
increases expression
ISO
cupric oxide results in increased expression of HSPA13 mRNA
CTD
PMID:22077320
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
cupric oxide results in increased expression of HSPA1A mRNA; cupric oxide results in increased expression of HSPA1A protein
CTD
PMID:25470785 PMID:32285662
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
cupric oxide results in increased expression of HSPA6 mRNA
CTD
PMID:22077320 PMID:24343273
NCBI chr13:83,273,176...83,274,317
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
cupric oxide results in increased expression of HSPA8 protein
CTD
PMID:25470785
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hspa9
heat shock protein family A (Hsp70) member 9
decreases expression
ISO
cupric oxide results in decreased expression of HSPA9 protein
CTD
PMID:25470785
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of HSPB1 protein
CTD
PMID:25470785
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Hspb8
heat shock protein family B (small) member 8
increases expression
ISO
cupric oxide results in increased expression of HSPB8 mRNA
CTD
PMID:22077320
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
G
Hspe1
heat shock protein family E (Hsp10) member 1
decreases expression
ISO
cupric oxide results in decreased expression of HSPE1 protein
CTD
PMID:25470785
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
G
Hsph1
heat shock protein family H (Hsp110) member 1
increases expression
ISO
cupric oxide results in increased expression of HSPH1 mRNA
CTD
PMID:22077320
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
G
Htra3
HtrA serine peptidase 3
increases expression
ISO
cupric oxide results in increased expression of HTRA3 mRNA
CTD
PMID:22077320
NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315
G
Hus1
HUS1 checkpoint clamp component
increases expression
ISO
cupric oxide results in increased expression of HUS1 mRNA
CTD
PMID:22077320
NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
G
Hyls1
HYLS1, centriolar and ciliogenesis associated
decreases expression
ISO
cupric oxide results in decreased expression of HYLS1 mRNA
CTD
PMID:22077320
NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760
G
Igf2
insulin-like growth factor 2
increases expression
ISO
cupric oxide results in increased expression of IGF2 mRNA
CTD
PMID:22077320
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Igfbp3
insulin-like growth factor binding protein 3
decreases expression
ISO
cupric oxide results in decreased expression of IGFBP3 mRNA
CTD
PMID:22077320
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
cupric oxide results in increased expression of and results in increased secretion of IL1A protein
CTD
PMID:22954531
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il6
interleukin 6
multiple interactions increases secretion affects expression
ISO
cupric oxide results in increased expression of and results in increased secretion of IL6 protein cupric oxide results in increased secretion of IL6 protein cupric oxide affects the expression of IL6 mRNA
CTD
PMID:22954531 PMID:28705761
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ilf3
interleukin enhancer binding factor 3
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of ILF3 protein
CTD
PMID:25470785
NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
G
Impa1
inositol monophosphatase 1
decreases expression
ISO
cupric oxide analog results in decreased expression of IMPA1 protein
CTD
PMID:23882024
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
G
Ing4
inhibitor of growth family, member 4
increases expression
ISO
cupric oxide results in increased expression of ING4 mRNA
CTD
PMID:22077320
NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265
G
Insig1
insulin induced gene 1
increases expression
ISO
cupric oxide results in increased expression of INSIG1 mRNA
CTD
PMID:22077320
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
G
Ipp
intracisternal A particle-promoted polypeptide
decreases expression
ISO
cupric oxide results in decreased expression of IPP mRNA
CTD
PMID:22077320
NCBI chr 5:129,962,528...130,001,237
Ensembl chr 5:129,962,643...130,001,242
G
Iqgap1
IQ motif containing GTPase activating protein 1
increases expression
ISO
cupric oxide results in increased expression of IQGAP1 protein
CTD
PMID:25470785
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
G
Irs1
insulin receptor substrate 1
decreases expression
ISO
cupric oxide results in decreased expression of IRS1 mRNA
CTD
PMID:22077320
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
G
Isg20
interferon stimulated exonuclease gene 20
increases expression
ISO
cupric oxide results in increased expression of ISG20 mRNA
CTD
PMID:22077320
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
G
Isy1
ISY1 splicing factor homolog
increases expression
ISO
cupric oxide results in increased expression of ISY1 mRNA
CTD
PMID:22077320
NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188
G
Jdp2
Jun dimerization protein 2
increases expression
ISO
cupric oxide results in increased expression of JDP2 mRNA
CTD
PMID:22077320
NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
G
Jpt1
Jupiter microtubule associated homolog 1
decreases expression
ISO
cupric oxide results in decreased expression of JPT1 mRNA
CTD
PMID:22077320
NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
cupric oxide results in increased expression of JUN mRNA
CTD
PMID:32285662
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kbtbd4
kelch repeat and BTB domain containing 4
increases expression
ISO
cupric oxide results in increased expression of KBTBD4 mRNA
CTD
PMID:22077320
NCBI chr 3:76,883,671...76,889,769
Ensembl chr 3:76,883,014...76,890,799
G
Kbtbd8
kelch repeat and BTB domain containing 8
increases expression
ISO
cupric oxide results in increased expression of KBTBD8 mRNA
CTD
PMID:22077320
NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
G
Keap1
Kelch-like ECH-associated protein 1
decreases expression
ISO
cupric oxide results in decreased expression of KEAP1 mRNA
CTD
PMID:32285662
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Kif18a
kinesin family member 18A
decreases expression
ISO
cupric oxide results in decreased expression of KIF18A mRNA
CTD
PMID:22077320
NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
G
Kif18b
kinesin family member 18B
decreases expression
ISO
cupric oxide results in decreased expression of KIF18B mRNA
CTD
PMID:22077320
NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
G
Kif20a
kinesin family member 20A
decreases expression
ISO
cupric oxide results in decreased expression of KIF20A mRNA
CTD
PMID:22077320
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
G
Kif20b
kinesin family member 20B
decreases expression
ISO
cupric oxide results in decreased expression of KIF20B mRNA
CTD
PMID:22077320
NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
G
Kif23
kinesin family member 23
decreases expression
ISO
cupric oxide results in decreased expression of KIF23 mRNA
CTD
PMID:22077320
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
G
Kifc1
kinesin family member C1
decreases expression
ISO
cupric oxide results in decreased expression of KIFC1 mRNA
CTD
PMID:22077320
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
G
Klf7
KLF transcription factor 7
increases expression
ISO
cupric oxide results in increased expression of KLF7 mRNA
CTD
PMID:22077320
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
G
Klhl18
kelch-like family member 18
increases expression
ISO
cupric oxide results in increased expression of KLHL18 mRNA
CTD
PMID:22077320
NCBI chr 8:110,400,679...110,459,442
Ensembl chr 8:110,400,681...110,459,323
G
Klhl42
kelch-like family, member 42
decreases expression
ISO
cupric oxide results in decreased expression of KLHL42 mRNA
CTD
PMID:22077320
NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
G
Knstrn
kinetochore-localized astrin/SPAG5 binding protein
decreases expression
ISO
cupric oxide results in decreased expression of KNSTRN mRNA
CTD
PMID:22077320
NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
G
Larp4
La ribonucleoprotein 4
increases expression
ISO
cupric oxide results in increased expression of LARP4 mRNA
CTD
PMID:22077320
NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811
G
Lat
linker for activation of T cells
increases expression
ISO
cupric oxide results in increased expression of LAT mRNA
CTD
PMID:22077320
NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578
G
Lats2
large tumor suppressor kinase 2
increases expression
ISO
cupric oxide results in increased expression of LATS2 mRNA
CTD
PMID:22077320
NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
G
Lgals1
galectin 1
increases expression
ISO
cupric oxide results in increased expression of LGALS1 protein
CTD
PMID:25470785
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
G
Lig1
DNA ligase 1
increases expression
ISO
cupric oxide results in increased expression of LIG1 mRNA
CTD
PMID:32285662
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
G
Lima1
LIM domain and actin binding 1
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of LIMA1 protein
CTD
PMID:25470785
NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
G
Limk2
LIM domain kinase 2
decreases expression
ISO
cupric oxide results in decreased expression of LIMK2 mRNA
CTD
PMID:22077320
NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007
G
Lmnb1
lamin B1
decreases expression
ISO
cupric oxide results in decreased expression of LMNB1 mRNA; cupric oxide results in decreased expression of LMNB1 protein
CTD
PMID:22077320 PMID:25470785
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
G
Lmnb2
lamin B2
decreases expression
ISO
cupric oxide results in decreased expression of LMNB2 mRNA
CTD
PMID:22077320
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
G
Lrrc59
leucine rich repeat containing 59
increases expression
ISO
cupric oxide results in increased expression of LRRC59 protein
CTD
PMID:25470785
NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533
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Maff
MAF bZIP transcription factor F
increases expression
ISO
cupric oxide results in increased expression of MAFF mRNA
CTD
PMID:22077320
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
cupric oxide results in increased expression of MAFG mRNA
CTD
PMID:22077320
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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Mafk
MAF bZIP transcription factor K
increases expression
ISO
cupric oxide results in increased expression of MAFK mRNA
CTD
PMID:22077320
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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Magoh
mago homolog, exon junction complex subunit
increases expression
ISO
cupric oxide results in increased expression of MAGOH mRNA
CTD
PMID:22077320
NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617
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Map1b
microtubule-associated protein 1B
affects phosphorylation
ISO
cupric oxide affects the phosphorylation of MAP1B protein
CTD
PMID:25470785
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
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Map3k21
mitogen-activated protein kinase kinase kinase 21
decreases expression
ISO
cupric oxide results in decreased expression of MAP3K21 mRNA
CTD
PMID:22077320
NCBI chr19:53,880,032...53,913,560
Ensembl chr19:53,880,238...53,913,576
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Map4
microtubule-associated protein 4
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of MAP4 protein
CTD
PMID:25470785
NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362
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Mapk1
mitogen activated protein kinase 1
increases activity
ISO
cupric oxide analog results in increased activity of MAPK1 protein
CTD
PMID:25336953
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
increases activity
ISO
cupric oxide analog results in increased activity of MAPK3 protein
CTD
PMID:25336953
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Marf1
meiosis regulator and mRNA stability factor 1
increases expression
ISO
cupric oxide results in increased expression of MARF1 mRNA
CTD
PMID:22077320
NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753
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Mb
myoglobin
multiple interactions increases secretion
EXP
costus absolute inhibits the reaction [cupric oxide analog results in increased secretion of MB protein]
CTD
PMID:36286243
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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Mcm2
minichromosome maintenance complex component 2
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of MCM2 protein
CTD
PMID:25470785
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Mcm4
minichromosome maintenance complex component 4
decreases expression
ISO
cupric oxide results in decreased expression of MCM4 mRNA
CTD
PMID:22077320
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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Mcm6
minichromosome maintenance complex component 6
decreases expression
ISO
cupric oxide results in decreased expression of MCM6 mRNA
CTD
PMID:22077320
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mdh1
malate dehydrogenase 1
decreases expression
ISO
cupric oxide analog results in decreased expression of MDH1 protein
CTD
PMID:23882024
NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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Med13
mediator complex subunit 13
increases expression
ISO
cupric oxide results in increased expression of MED13 mRNA
CTD
PMID:22077320
NCBI chr10:71,086,978...71,176,535
Ensembl chr10:71,090,516...71,177,242
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Med21
mediator complex subunit 21
increases expression
ISO
cupric oxide results in increased expression of MED21 mRNA
CTD
PMID:22077320
NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548
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Melk
maternal embryonic leucine zipper kinase
decreases expression
ISO
cupric oxide results in decreased expression of MELK mRNA
CTD
PMID:22077320
NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937
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Mettl14
methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
increases expression
ISO
cupric oxide results in increased expression of METTL14 mRNA
CTD
PMID:22077320
NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821
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Mlxipl
MLX interacting protein-like
increases expression
ISO
cupric oxide results in increased expression of MLXIPL mRNA
CTD
PMID:22077320
NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
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Mmp15
matrix metallopeptidase 15
increases expression
ISO
cupric oxide results in increased expression of MMP15 protein
CTD
PMID:25470785
NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
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Mob3b
MOB kinase activator 3B
decreases expression
ISO
cupric oxide results in decreased expression of MOB3B mRNA
CTD
PMID:22077320
NCBI chr 5:49,546,254...49,737,934
Ensembl chr 5:49,545,815...49,737,934
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Msi2
musashi RNA-binding protein 2
increases expression
ISO
cupric oxide results in increased expression of MSI2 mRNA
CTD
PMID:22077320
NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157
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Msn
moesin
increases expression
ISO
cupric oxide results in increased expression of MSN protein
CTD
PMID:25470785
NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
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Mt1
metallothionein 1
increases expression
ISO
cupric oxide analog results in increased expression of MT1A mRNA; cupric oxide results in increased expression of MT1A mRNA
CTD
PMID:22077320 PMID:24815816 PMID:33839236
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt1-ps3
metallothionein 1, pseudogene 3
increases expression
ISO
cupric oxide results in increased expression of MT1E mRNA
CTD
PMID:22077320
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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Mt2A
metallothionein 2A
increases expression
ISO
cupric oxide results in increased expression of MT2A mRNA
CTD
PMID:22077320 PMID:32285662 PMID:33839236
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mtf1
metal-regulatory transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of MTF1 mRNA
CTD
PMID:22077320
NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Mtrex
Mtr4 exosome RNA helicase
decreases expression
ISO
cupric oxide results in decreased expression of MTREX protein
CTD
PMID:25470785
NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
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Mtx1
Metaxin 1
increases expression
ISO
cupric oxide results in increased expression of MTX1 mRNA
CTD
PMID:32285662
NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982
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Muc2
mucin 2, oligomeric mucus/gel-forming
increases expression
ISO
cupric oxide results in increased expression of MUC2 mRNA
CTD
PMID:33839236
NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
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Mvd
mevalonate diphosphate decarboxylase
increases expression
ISO
cupric oxide results in increased expression of MVD mRNA
CTD
PMID:22077320
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mxi1
MAX interactor 1, dimerization protein
increases expression
ISO
cupric oxide results in increased expression of MXI1 mRNA
CTD
PMID:22077320
NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
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Mybbp1a
MYB binding protein 1a
decreases expression
ISO
cupric oxide results in decreased expression of MYBBP1A mRNA
CTD
PMID:22077320
NCBI chr10:57,056,897...57,067,258
Ensembl chr10:57,056,874...57,067,255
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Mybl1
MYB proto-oncogene like 1
decreases expression
ISO
cupric oxide results in decreased expression of MYBL1 mRNA
CTD
PMID:22077320
NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
cupric oxide results in decreased expression of MYC mRNA
CTD
PMID:22077320
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myh9
myosin, heavy chain 9
decreases expression
ISO
cupric oxide results in decreased expression of MYH9 mRNA
CTD
PMID:22077320
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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Mynn
myoneurin
increases expression
ISO
cupric oxide results in increased expression of MYNN mRNA
CTD
PMID:22077320
NCBI chr 2:112,779,654...112,797,188
Ensembl chr 2:112,779,657...112,796,397
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Myo1b
myosin Ib
decreases expression
ISO
cupric oxide results in decreased expression of MYO1B mRNA
CTD
PMID:22077320
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
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Myo5c
myosin VC
decreases expression
ISO
cupric oxide results in decreased expression of MYO5C mRNA
CTD
PMID:22077320
NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
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Naca
nascent polypeptide associated complex subunit alpha
increases expression
ISO
cupric oxide results in increased expression of NACA protein
CTD
PMID:25470785
NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992
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Nap1l4
nucleosome assembly protein 1-like 4
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of NAP1L4 protein
CTD
PMID:25470785
NCBI chr 1:198,709,697...198,746,093
Ensembl chr 1:198,709,701...198,746,020
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Nap1l5
nucleosome assembly protein 1-like 5
increases expression
ISO
cupric oxide results in increased expression of NAP1L5 mRNA
CTD
PMID:22077320
NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654
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Nat1
N-acetyltransferase 1
increases expression
ISO
cupric oxide results in increased expression of NAT1 mRNA
CTD
PMID:32285662
NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
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Ncapd2
non-SMC condensin I complex, subunit D2
decreases expression
ISO
cupric oxide results in decreased expression of NCAPD2 mRNA
CTD
PMID:22077320
NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
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Ncl
nucleolin
increases expression
ISO
cupric oxide results in increased expression of NCL protein
CTD
PMID:25470785
NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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Ndc80
NDC80 kinetochore complex component
decreases expression
ISO
cupric oxide results in decreased expression of NDC80 mRNA
CTD
PMID:22077320
NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
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Ndufs8
NADH:ubiquinone oxidoreductase core subunit S8
increases expression
ISO
cupric oxide analog results in increased expression of NDUFS8 protein
CTD
PMID:23882024
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
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Nfatc1
nuclear factor of activated T-cells 1
increases expression
ISO
cupric oxide results in increased expression of NFATC1 mRNA
CTD
PMID:22077320
NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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Nfe2l3
NFE2 like bZIP transcription factor 3
decreases expression
ISO
cupric oxide results in decreased expression of NFE2L3 mRNA
CTD
PMID:22077320
NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
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Nfil3
nuclear factor, interleukin 3 regulated
increases expression
ISO
cupric oxide results in increased expression of NFIL3 mRNA
CTD
PMID:22077320
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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Nfkb2
nuclear factor kappa B subunit 2
increases expression
ISO
cupric oxide results in increased expression of NFKB2 mRNA
CTD
PMID:32285662
NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
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Nlk
nemo like kinase
increases expression
ISO
cupric oxide results in increased expression of NLK mRNA
CTD
PMID:22077320
NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730
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Nono
non-POU domain containing, octamer-binding
decreases expression
ISO
cupric oxide results in decreased expression of NONO protein
CTD
PMID:25470785
NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952
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Npm1
nucleophosmin 1
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of NPM1 protein
CTD
PMID:25470785
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression
ISO
cupric oxide results in decreased expression of NQO1 mRNA
CTD
PMID:32285662
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
decreases expression
ISO
cupric oxide results in decreased expression of NR2F2 mRNA
CTD
PMID:22077320
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression decreases response to substance
ISO
cupric oxide results in increased expression of NR4A1 mRNA; cupric oxide results in increased expression of NR4A1 protein NR4A1 protein results in decreased susceptibility to cupric oxide
CTD
PMID:22077320
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
cupric oxide results in increased expression of NR4A3 mRNA; cupric oxide results in increased expression of NR4A3 protein
CTD
PMID:22077320
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of NUCKS1 protein
CTD
PMID:25470785
NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
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Nuf2
NUF2 component of NDC80 kinetochore complex
decreases expression
ISO
cupric oxide results in decreased expression of NUF2 mRNA
CTD
PMID:22077320
NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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Nupr1
nuclear protein 1, transcriptional regulator
increases expression
ISO
cupric oxide results in increased expression of NUPR1 mRNA
CTD
PMID:22077320
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
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Obsl1
obscurin like cytoskeletal adaptor 1
decreases expression
ISO
cupric oxide results in decreased expression of OBSL1 mRNA
CTD
PMID:22077320
NCBI chr 9:76,967,802...76,993,771
Ensembl chr 9:76,974,253...76,993,560
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Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase
increases expression
ISO
cupric oxide results in increased expression of OGT mRNA
CTD
PMID:22077320
NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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Olfml2a
olfactomedin-like 2A
decreases expression
ISO
cupric oxide results in decreased expression of OLFML2A mRNA
CTD
PMID:22077320
NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909
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Or5ar1
olfactory receptor family 5 subfamily AR member 1
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of OR5AR1 protein
CTD
PMID:25470785
NCBI chr 3:70,907,592...70,908,524
Ensembl chr 3:70,906,547...70,912,666
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Or5l14b
olfactory receptor family 5 subfamily L member 14B
increases expression
ISO
cupric oxide results in increased expression of OR5L2 mRNA
CTD
PMID:22077320
NCBI chr 3:73,432,677...73,433,615
Ensembl chr 3:73,432,677...73,433,615
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Otub1
OTU deubiquitinase, ubiquitin aldehyde binding 1
decreases expression
ISO
cupric oxide analog results in decreased expression of OTUB1 protein
CTD
PMID:23882024
NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483
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Otud4
OTU deubiquitinase 4
decreases expression
ISO
cupric oxide results in decreased expression of OTUD4 mRNA
CTD
PMID:22077320
NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815
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P4hb
prolyl 4-hydroxylase subunit beta
decreases expression
ISO
cupric oxide results in decreased expression of P4HB protein
CTD
PMID:25470785
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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Pabpc6
poly(A) binding protein, cytoplasmic 6
decreases expression
ISO
cupric oxide results in decreased expression of PABPC3 mRNA
CTD
PMID:22077320
NCBI chr 1:51,045,264...51,048,340
Ensembl chr 1:51,045,233...51,048,340
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Paip2
poly(A) binding protein interacting protein 2
increases expression
ISO
cupric oxide results in increased expression of PAIP2 mRNA
CTD
PMID:22077320
NCBI chr18:27,199,762...27,218,359
Ensembl chr18:27,199,796...27,214,863
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Pald1
phosphatase domain containing, paladin 1
decreases expression
ISO
cupric oxide results in decreased expression of PALD1 mRNA
CTD
PMID:22077320
NCBI chr20:29,269,814...29,334,850
Ensembl chr20:29,270,193...29,334,858
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Papola
poly (A) polymerase alpha
increases expression
ISO
cupric oxide results in increased expression of PAPOLA mRNA
CTD
PMID:22077320
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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Parp4
poly (ADP-ribose) polymerase family, member 4
decreases expression
ISO
cupric oxide results in decreased expression of PARP4 mRNA
CTD
PMID:22077320
NCBI chr15:30,690,503...30,792,868
Ensembl chr15:30,686,613...30,828,810
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Pcbp1
poly(rC) binding protein 1
increases expression
ISO
cupric oxide results in increased expression of PCBP1 protein
CTD
PMID:25470785
NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500
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Pcdh9
protocadherin 9
decreases expression
ISO
cupric oxide results in decreased expression of PCDH9 mRNA
CTD
PMID:22077320
NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538
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Pcf11
PCF11 cleavage and polyadenylation factor subunit
increases expression
ISO
cupric oxide results in increased expression of PCF11 mRNA
CTD
PMID:22077320
NCBI chr 1:146,694,045...146,724,030
Ensembl chr 1:146,697,646...146,724,124
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Pcna
proliferating cell nuclear antigen
decreases expression increases expression multiple interactions
ISO EXP
cupric oxide results in decreased expression of PCNA mRNA cupric oxide analog results in decreased expression of PCNA protein cupric oxide analog results in increased expression of PCNA protein costus absolute inhibits the reaction [cupric oxide analog results in increased expression of PCNA protein]
CTD
PMID:22077320 PMID:23882024 PMID:36286243
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdgfa
platelet derived growth factor subunit A
decreases expression
ISO
cupric oxide results in decreased expression of PDGFA mRNA
CTD
PMID:22077320
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdia3
protein disulfide isomerase family A, member 3
decreases expression
ISO
cupric oxide results in decreased expression of PDIA3 protein
CTD
PMID:25470785
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pdia4
protein disulfide isomerase family A, member 4
decreases expression
ISO
cupric oxide results in decreased expression of PDIA4 protein
CTD
PMID:25470785
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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Pdia6
protein disulfide isomerase family A, member 6
decreases expression
ISO
cupric oxide results in decreased expression of PDIA6 protein
CTD
PMID:25470785
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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Pfn1
profilin 1
decreases expression
ISO
cupric oxide results in decreased expression of PFN1 protein
CTD
PMID:25470785
NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
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Phb2
prohibitin 2
increases expression
ISO
cupric oxide results in increased expression of PHB2 protein
CTD
PMID:25470785
NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
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Phc3
polyhomeotic homolog 3
increases expression
ISO
cupric oxide results in increased expression of PHC3 mRNA
CTD
PMID:22077320
NCBI chr 2:112,408,709...112,483,719
Ensembl chr 2:112,408,531...112,476,540
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Phf1
PHD finger protein 1
increases expression
ISO
cupric oxide results in increased expression of PHF1 mRNA
CTD
PMID:22077320
NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
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Phtf1
putative homeodomain transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of PHTF1 mRNA
CTD
PMID:22077320
NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
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Picalm
phosphatidylinositol binding clathrin assembly protein
increases expression
ISO
cupric oxide results in increased expression of PICALM protein
CTD
PMID:25470785
NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
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Pif1
PIF1 5'-to-3' DNA helicase
decreases expression
ISO
cupric oxide results in decreased expression of PIF1 mRNA
CTD
PMID:22077320
NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
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Pilrb2l8
paired immunoglobin like type 2 receptor beta 2 like 8
increases expression
ISO
cupric oxide results in increased expression of ZNF37A mRNA
CTD
PMID:22077320
NCBI chr12:17,744,315...17,756,074
Ensembl chr12:17,752,830...17,755,922
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Plagl1
PLAG1 like zinc finger 1
decreases expression
ISO
cupric oxide results in decreased expression of PLAGL1 mRNA
CTD
PMID:22077320
NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
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Plk2
polo-like kinase 2
decreases expression
ISO
cupric oxide results in decreased expression of PLK2 mRNA
CTD
PMID:22077320
NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
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Plrg1
pleiotropic regulator 1
increases expression
ISO
cupric oxide results in increased expression of PLRG1 mRNA
CTD
PMID:22077320
NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
cupric oxide results in increased expression of PMAIP1 mRNA
CTD
PMID:32285662
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Pms1
PMS1 homolog 1, mismatch repair system component
decreases expression
ISO
cupric oxide results in decreased expression of PMS1 mRNA
CTD
PMID:22077320
NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237
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Pnpla8
patatin-like phospholipase domain containing 8
increases expression
ISO
cupric oxide results in increased expression of PNPLA8 mRNA
CTD
PMID:22077320
NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734
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Podxl
podocalyxin-like
decreases expression
ISO
cupric oxide results in decreased expression of PODXL mRNA
CTD
PMID:22077320
NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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Poli
DNA polymerase iota
decreases expression
ISO
cupric oxide results in decreased expression of POLI mRNA
CTD
PMID:22077320
NCBI chr18:64,116,774...64,134,373
Ensembl chr18:64,116,774...64,163,418
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Ppia
peptidylprolyl isomerase A
decreases expression
ISO
cupric oxide analog results in decreased expression of PPIA protein
CTD
PMID:23882024
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Ppib
peptidylprolyl isomerase B
increases expression
ISO
cupric oxide results in increased expression of PPIB protein
CTD
PMID:25470785
NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
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Ppp1r3b
protein phosphatase 1, regulatory subunit 3B
increases expression
ISO
cupric oxide results in increased expression of PPP1R3B mRNA
CTD
PMID:22077320
NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
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Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
increases expression
ISO
cupric oxide results in increased expression of PPP2R1A protein
CTD
PMID:25470785
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
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Prdx1
peroxiredoxin 1
increases expression
ISO
cupric oxide analog results in increased expression of PRDX1 protein
CTD
PMID:23882024
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx2
peroxiredoxin 2
increases expression
ISO
cupric oxide results in increased expression of PRDX2 protein
CTD
PMID:25470785
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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Prdx6
peroxiredoxin 6
increases expression decreases expression
ISO
cupric oxide results in increased expression of PRDX6 protein cupric oxide results in decreased expression of PRDX6 protein
CTD
PMID:23882024 PMID:25470785
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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Prkar1a
protein kinase cAMP-dependent type I regulatory subunit alpha
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of PRKAR1A protein
CTD
PMID:25470785
NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
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Prkcsh
PRKCSH beta subunit of glucosidase II
decreases expression
ISO
cupric oxide results in decreased expression of PRKCSH protein
CTD
PMID:25470785
NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
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Prl
prolactin
multiple interactions
EXP
[cupric oxide co-treated with lead oxide] results in increased expression of PRL protein
CTD
PMID:28212817
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Prop1
PROP paired-like homeobox 1
increases expression
ISO
cupric oxide results in increased expression of PROP1 mRNA
CTD
PMID:22077320
NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434
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Prpf18
pre-mRNA processing factor 18
increases expression
ISO
cupric oxide results in increased expression of PRPF18 mRNA
CTD
PMID:22077320
NCBI chr17:73,630,560...73,661,210
Ensembl chr17:73,630,571...73,690,979
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Prss23
serine protease 23
decreases expression
ISO
cupric oxide results in decreased expression of PRSS23 mRNA
CTD
PMID:22077320
NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091
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Pskh1
protein serine kinase H1
decreases expression
ISO
cupric oxide results in decreased expression of PSKH1 mRNA
CTD
PMID:22077320
NCBI chr19:33,794,919...33,827,040
Ensembl chr19:33,794,935...33,827,032
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Psrc1
proline and serine rich coiled-coil 1
decreases expression
ISO
cupric oxide results in decreased expression of PSRC1 mRNA
CTD
PMID:22077320
NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
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Ptpn13
protein tyrosine phosphatase, non-receptor type 13
decreases expression
ISO
cupric oxide results in decreased expression of PTPN13 mRNA
CTD
PMID:22077320
NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
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Pttg1
PTTG1 regulator of sister chromatid separation, securin
decreases expression
ISO
cupric oxide results in decreased expression of PTTG1 mRNA
CTD
PMID:22077320
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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Rab1b
RAB1B, member RAS oncogene family
decreases expression
ISO
cupric oxide results in decreased expression of RAB1B protein
CTD
PMID:25470785
NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868 Ensembl chr X:202,405,759...202,413,868
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Racgap1
Rac GTPase-activating protein 1
decreases expression
ISO
cupric oxide results in decreased expression of RACGAP1 mRNA
CTD
PMID:22077320
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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Rad23a
RAD23 homolog A, nucleotide excision repair protein
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of RAD23A protein
CTD
PMID:25470785
NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
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Rad51
RAD51 recombinase
increases expression
ISO
cupric oxide results in increased expression of RAD51 mRNA
CTD
PMID:32285662
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
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Rapgef6
Rap guanine nucleotide exchange factor 6
decreases expression
ISO
cupric oxide results in decreased expression of RAPGEF6 mRNA
CTD
PMID:22077320
NCBI chr10:38,655,854...38,824,227
Ensembl chr10:38,655,867...38,823,211
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Rbbp6
RB binding protein 6, ubiquitin ligase
increases expression
ISO
cupric oxide results in increased expression of RBBP6 mRNA
CTD
PMID:22077320
NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
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Rbbp8
RB binding protein 8, endonuclease
decreases expression
ISO
cupric oxide results in decreased expression of RBBP8 mRNA
CTD
PMID:22077320
NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
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Rfx4
regulatory factor X4
increases phosphorylation
ISO
cupric oxide results in increased phosphorylation of RFX4 protein
CTD
PMID:25470785
NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
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Riok3
RIO kinase 3
increases expression
ISO
cupric oxide results in increased expression of RIOK3 mRNA
CTD
PMID:22077320
NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
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Rit1
Ras-like without CAAX 1
increases expression
ISO
cupric oxide results in increased expression of RIT1 mRNA
CTD
PMID:22077320
NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
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Rlf
RLF zinc finger
increases expression
ISO
cupric oxide results in increased expression of RLF mRNA
CTD
PMID:22077320
NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257
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Rlim
ring finger protein, LIM domain interacting
increases expression
ISO
cupric oxide results in increased expression of RLIM mRNA
CTD
PMID:22077320
NCBI chr X:68,983,259...69,004,368
Ensembl chr X:68,988,375...69,004,271
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Rnf11
ring finger protein 11
increases expression
ISO
cupric oxide results in increased expression of RNF11 mRNA
CTD
PMID:22077320
NCBI chr 5:124,212,433...124,243,125
Ensembl chr 5:124,212,445...124,234,750
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Rnf185
ring finger protein 185
increases expression
ISO
cupric oxide results in increased expression of RNF185 mRNA
CTD
PMID:22077320
NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
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Rnmt
RNA (guanine-7-) methyltransferase
increases expression
ISO
cupric oxide results in increased expression of RNMT mRNA
CTD
PMID:22077320
NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
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Ror1
receptor tyrosine kinase-like orphan receptor 1
decreases expression
ISO
cupric oxide results in decreased expression of ROR1 mRNA
CTD
PMID:22077320
NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
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Rp2
RP2 activator of ARL3 GTPase
increases expression
ISO
cupric oxide results in increased expression of RP2 mRNA
CTD
PMID:22077320
NCBI chr X:1,872,582...1,916,704
Ensembl chr X:1,873,306...1,916,688
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Rplp0
ribosomal protein lateral stalk subunit P0
increases expression
ISO
cupric oxide results in increased expression of RPLP0 protein cupric oxide analog results in increased expression of RPLP0 protein
CTD
PMID:23882024 PMID:25470785
NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
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Rplp1
ribosomal protein lateral stalk subunit P1
increases expression
ISO
cupric oxide results in increased expression of RPLP1 protein
CTD
PMID:25470785
NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
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Rps2
ribosomal protein S2
increases expression
ISO
cupric oxide results in increased expression of RPS2 protein
CTD
PMID:25470785
NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
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Rps3
ribosomal protein S3
increases expression
ISO
cupric oxide results in increased expression of RPS3 protein
CTD
PMID:25470785
NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
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Rps5
ribosomal protein S5
increases expression
ISO
cupric oxide results in increased expression of RPS5 protein
CTD
PMID:25470785
NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
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Rps7
ribosomal protein S7
decreases expression
ISO
cupric oxide results in decreased expression of RPS7 protein
CTD
PMID:25470785
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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Rpsa
ribosomal protein SA
increases expression
ISO
cupric oxide results in increased expression of RPSA protein
CTD
PMID:25470785
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Rpusd4
RNA pseudouridine synthase D4
increases expression
ISO
cupric oxide results in increased expression of RPUSD4 mRNA
CTD
PMID:22077320
NCBI chr 8:33,617,384...33,626,873
Ensembl chr 8:33,617,379...33,626,873
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Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
ISO
cupric oxide results in decreased expression of RRM2 mRNA
CTD
PMID:22077320
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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Rybp
RING1 and YY1 binding protein
increases expression
ISO
cupric oxide results in increased expression of RYBP mRNA
CTD
PMID:22077320
NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
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Sass6
SAS-6 centriolar assembly protein
decreases expression
ISO
cupric oxide results in decreased expression of SASS6 mRNA
CTD
PMID:22077320
NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
cupric oxide results in increased expression of SAT1 mRNA
CTD
PMID:22077320
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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Sbno1
strawberry notch homolog 1
increases expression
ISO
cupric oxide results in increased expression of SBNO1 mRNA
CTD
PMID:22077320
NCBI chr12:32,175,176...32,234,200
Ensembl chr12:32,185,485...32,230,158
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Scml1
Scm polycomb group protein like 1
increases expression
ISO
cupric oxide results in increased expression of SCML1 mRNA
CTD
PMID:22077320
NCBI chr X:32,893,100...32,912,686
Ensembl chr X:32,894,327...32,911,366
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Scn10a
sodium voltage-gated channel alpha subunit 10
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of SCN10A protein
CTD
PMID:25470785
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
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Sec14l1
SEC14-like lipid binding 1
increases expression
ISO
cupric oxide results in increased expression of SEC14L1 mRNA
CTD
PMID:22077320
NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068
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Sec61a2
SEC61 translocon subunit alpha 2
increases expression
ISO
cupric oxide results in increased expression of SEC61A2 mRNA
CTD
PMID:22077320
NCBI chr17:72,407,574...72,445,630
Ensembl chr17:72,407,671...72,434,494
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Selenop
selenoprotein P
decreases expression
ISO
cupric oxide results in decreased expression of SELENOP mRNA
CTD
PMID:32285662
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Serpine1
serpin family E member 1
increases expression multiple interactions
ISO
cupric oxide results in increased expression of SERPINE1 mRNA; cupric oxide results in increased expression of SERPINE1 protein SB 203580 inhibits the reaction [cupric oxide results in increased expression of SERPINE1 mRNA]
CTD
PMID:20171267
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Setbp1
SET binding protein 1
decreases expression
ISO
cupric oxide results in decreased expression of SETBP1 mRNA
CTD
PMID:22077320
NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556
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Setd2
SET domain containing 2, histone lysine methyltransferase
decreases phosphorylation
ISO
cupric oxide results in decreased phosphorylation of SETD2 protein
CTD
PMID:25470785
NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489
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Sfpq
splicing factor proline and glutamine rich
increases expression
ISO
cupric oxide results in increased expression of SFPQ protein
CTD
PMID:25470785
NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
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Sfrp1
secreted frizzled-related protein 1
decreases expression
ISO
cupric oxide results in decreased expression of SFRP1 mRNA
CTD
PMID:22077320
NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
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Sim2
SIM bHLH transcription factor 2
decreases expression
ISO
cupric oxide results in decreased expression of SIM2 mRNA
CTD
PMID:22077320
NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
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Sin3b
SIN3 transcription regulator family member B
increases expression
ISO
cupric oxide results in increased expression of SIN3B mRNA
CTD
PMID:22077320
NCBI chr16:17,123,277...17,159,978
Ensembl chr16:17,123,434...17,159,978
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Sirt6
sirtuin 6
increases expression
ISO
cupric oxide results in increased expression of SIRT6 mRNA
CTD
PMID:22077320
NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
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Slc25a3
solute carrier family 25 member 3
decreases expression
ISO
cupric oxide results in decreased expression of SLC25A3 protein
CTD
PMID:25470785
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
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Slc25a44
solute carrier family 25, member 44
increases expression
ISO
cupric oxide results in increased expression of SLC25A44 mRNA
CTD
PMID:22077320
NCBI chr 2:173,868,317...173,883,137
Ensembl chr 2:173,868,320...173,883,020
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Slc27a2
solute carrier family 27 member 2
decreases expression
ISO
cupric oxide results in decreased expression of SLC27A2 mRNA
CTD
PMID:22077320
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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Slc30a1
solute carrier family 30 member 1
increases expression
ISO
cupric oxide results in increased expression of SLC30A1 mRNA
CTD
PMID:24343273 PMID:32285662
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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Slc31a1
solute carrier family 31 member 1
increases expression
ISO
cupric oxide analog results in increased expression of SLC31A1 mRNA; cupric oxide analog results in increased expression of SLC31A1 protein
CTD
PMID:24815816
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
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Slu7
SLU7 homolog, splicing factor
increases expression
ISO
cupric oxide results in increased expression of SLU7 mRNA
CTD
PMID:22077320
NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349
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Snai1
snail family transcriptional repressor 1
increases expression
ISO
cupric oxide results in increased expression of SNAI1 mRNA
CTD
PMID:22077320
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snd1
staphylococcal nuclease and tudor domain containing 1
increases expression
ISO
cupric oxide results in increased expression of SND1 protein
CTD
PMID:25470785
NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
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Snip1
Smad nuclear interacting protein 1
increases expression
ISO
cupric oxide results in increased expression of SNIP1 mRNA
CTD
PMID:22077320
NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845
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Snx8
sorting nexin 8
increases expression
ISO
cupric oxide results in increased expression of SNX8 mRNA
CTD
PMID:22077320
NCBI chr12:14,251,829...14,300,435
Ensembl chr12:14,251,859...14,300,432
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Sod1
superoxide dismutase 1
multiple interactions decreases expression increases expression
ISO
trans-sodium crocetinate inhibits the reaction [cupric oxide results in decreased expression of SOD1 mRNA] cupric oxide results in increased expression of SOD1 mRNA
CTD
PMID:25701151 PMID:32285662
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
increases expression multiple interactions decreases expression
ISO
cupric oxide results in increased expression of SOD2 mRNA trans-sodium crocetinate inhibits the reaction [cupric oxide results in decreased expression of SOD2 mRNA]
CTD
PMID:22077320 PMID:25701151 PMID:32285662
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sox8
SRY-box transcription factor 8
increases expression
ISO
cupric oxide results in increased expression of SOX8 mRNA
CTD
PMID:22077320
NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
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Sp1
Sp1 transcription factor
increases expression
ISO
cupric oxide results in increased expression of SP1 mRNA
CTD
PMID:22077320
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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Sptan1
spectrin, alpha, non-erythrocytic 1
increases expression
ISO
cupric oxide results in increased expression of SPTAN1 protein
CTD
PMID:25470785
NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
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Sptbn1
spectrin, beta, non-erythrocytic 1
decreases expression
ISO
cupric oxide results in decreased expression of SPTBN1 mRNA
CTD
PMID:22077320
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
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Srebf2
sterol regulatory element binding transcription factor 2
increases expression
ISO
cupric oxide results in increased expression of SREBF2 mRNA
CTD
PMID:22077320
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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Srgap2
SLIT-ROBO Rho GTPase activating protein 2
decreases expression
ISO
cupric oxide results in decreased expression of SRGAP2 mRNA
CTD
PMID:22077320
NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058
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St13
ST13, Hsp70 interacting protein
increases expression
ISO
cupric oxide results in increased expression of ST13 mRNA
CTD
PMID:22077320
NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
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Strap
serine/threonine kinase receptor associated protein
decreases expression
ISO
cupric oxide analog results in decreased expression of STRAP protein
CTD
PMID:23882024
NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828
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Supt4h1
SPT4 homolog, DSIF elongation factor subunit
increases expression
ISO
cupric oxide results in increased expression of SUPT4H1 mRNA
CTD
PMID:22077320
NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
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Taf13
TATA-box binding protein associated factor 13
increases expression
ISO
cupric oxide results in increased expression of TAF13 mRNA
CTD
PMID:22077320
NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
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Taf7
TATA-box binding protein associated factor 7
increases expression
ISO
cupric oxide results in increased expression of TAF7 mRNA
CTD
PMID:22077320
NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
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Taf8
TATA-box binding protein associated factor 8
increases expression
ISO
cupric oxide results in increased expression of TAF8 mRNA
CTD
PMID:22077320
NCBI chr 9:13,491,892...13,511,713
Ensembl chr 9:13,491,937...13,511,717
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Tagln2
transgelin 2
increases expression
ISO
cupric oxide results in increased expression of TAGLN2 protein
CTD
PMID:25470785
NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
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Tbc1d15
TBC1 domain family, member 15
increases expression
ISO
cupric oxide results in increased expression of TBC1D15 mRNA
CTD
PMID:22077320
NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175
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Tbc1d9b
TBC1 domain family member 9B
decreases expression
ISO
cupric oxide results in decreased expression of TBC1D9B mRNA
CTD
PMID:22077320
NCBI chr10:34,459,930...34,497,146
Ensembl chr10:34,459,953...34,497,145
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Tdg
thymine-DNA glycosylase
increases expression
ISO
cupric oxide results in increased expression of TDG mRNA
CTD
PMID:22077320
NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567
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Tead1
TEA domain transcription factor 1
increases expression
ISO
cupric oxide results in increased expression of TEAD1 mRNA
CTD
PMID:22077320
NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369
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Tfip11
tuftelin interacting protein 11
increases expression
ISO
cupric oxide results in increased expression of TFIP11 mRNA
CTD
PMID:22077320
NCBI chr12:44,299,619...44,311,851
Ensembl chr12:44,299,622...44,311,855
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Tgfb2
transforming growth factor, beta 2
decreases expression
ISO
cupric oxide results in decreased expression of TGFB2 mRNA
CTD
PMID:22077320
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Thap1
THAP domain containing 1
increases expression
ISO
cupric oxide results in increased expression of THAP1 mRNA
CTD
PMID:22077320
NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
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Thsd7a
thrombospondin type 1 domain containing 7A
decreases expression
ISO
cupric oxide results in decreased expression of THSD7A mRNA
CTD
PMID:22077320
NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:40,460,814...40,899,583
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Timm10b
translocase of inner mitochondrial membrane 10B
increases expression
ISO
cupric oxide results in increased expression of TIMM10B mRNA
CTD
PMID:22077320
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
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Tkt
transketolase
increases expression
ISO
cupric oxide results in increased expression of TKT protein
CTD
PMID:25470785
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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Tlnrd1
talin rod domain containing 1
decreases expression
ISO
cupric oxide results in decreased expression of TLNRD1 mRNA
CTD
PMID:22077320
NCBI chr 1:137,864,340...137,866,359
Ensembl chr 1:137,864,343...137,866,359
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Tmed4
transmembrane p24 trafficking protein 4
decreases expression
ISO
cupric oxide results in decreased expression of TMED4 protein
CTD
PMID:25470785
NCBI chr14:81,125,049...81,129,646
Ensembl chr14:81,125,053...81,129,631
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Tmem171
transmembrane protein 171
decreases expression
ISO
cupric oxide results in decreased expression of TMEM171 mRNA
CTD
PMID:22077320
NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049
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Tmod3
tropomodulin 3
increases expression
ISO
cupric oxide results in increased expression of TMOD3 protein
CTD
PMID:25470785
NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977
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Tmsb4x
thymosin beta 4, X-linked
decreases expression
ISO
cupric oxide results in decreased expression of TMSB4X mRNA
CTD
PMID:22077320
NCBI chr X:27,144,666...27,146,667
Ensembl chr X:27,128,610...27,146,667
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Tnf
tumor necrosis factor
multiple interactions
ISO
cupric oxide results in increased expression of and results in increased secretion of TNF protein
CTD
PMID:22954531
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tns3
tensin 3
decreases expression
ISO
cupric oxide results in decreased expression of TNS3 mRNA
CTD
PMID:22077320
NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
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Top2a
DNA topoisomerase II alpha
decreases expression
ISO
cupric oxide results in decreased expression of TOP2A mRNA
CTD
PMID:22077320
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tp53
tumor protein p53
decreases expression multiple interactions
ISO
cupric oxide results in decreased expression of TP53 mRNA cupric oxide analog results in decreased phosphorylation of and results in decreased expression of TP53 protein cupric oxide analog results in decreased phosphorylation of and results in decreased expression of TRP53 protein
CTD
PMID:22077320 PMID:25336953 PMID:32285662
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpm1
tropomyosin 1
decreases expression
ISO
cupric oxide results in decreased expression of TPM1 mRNA
CTD
PMID:22077320
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Tpx2
TPX2, microtubule nucleation factor
decreases expression
ISO
cupric oxide results in decreased expression of TPX2 mRNA
CTD
PMID:22077320
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Traf7
TNF receptor associated factor 7
decreases expression
ISO
cupric oxide results in decreased expression of TRAF7 mRNA
CTD
PMID:22077320
NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203
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Tram1
translocation associated membrane protein 1
decreases expression
ISO
cupric oxide results in decreased expression of TRAM1 mRNA
CTD
PMID:22077320
NCBI chr 5:5,642,579...5,667,666
Ensembl chr 5:5,642,546...5,686,971
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Trib3
tribbles pseudokinase 3
increases expression
ISO
cupric oxide results in increased expression of TRIB3 mRNA
CTD
PMID:22077320
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim14
tripartite motif-containing 14
decreases expression
ISO
cupric oxide results in decreased expression of TRIM14 mRNA
CTD
PMID:22077320
NCBI chr 5:60,800,568...60,824,858
Ensembl chr 5:60,800,032...60,824,858
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Trim59
tripartite motif-containing 59
decreases expression
ISO
cupric oxide results in decreased expression of TRIM59 mRNA
CTD
PMID:22077320
NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031
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Trim6
tripartite motif containing 6
decreases expression
ISO
cupric oxide results in decreased expression of TRIM6 mRNA
CTD
PMID:22077320
NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
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Triobp
TRIO and F-actin binding protein
decreases expression
ISO
cupric oxide results in decreased expression of TRIOBP mRNA
CTD
PMID:22077320
NCBI chr 7:110,505,916...110,569,301
Ensembl chr 7:110,506,248...110,562,474
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Ttc1
tetratricopeptide repeat domain 1
increases expression
ISO
cupric oxide results in increased expression of TTC1 mRNA
CTD
PMID:22077320
NCBI chr10:28,202,325...28,227,464
Ensembl chr10:28,202,325...28,227,472
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Ttf1
transcription termination factor 1
increases expression
ISO
cupric oxide results in increased expression of TTF1 mRNA
CTD
PMID:22077320
NCBI chr 3:12,384,626...12,409,257
Ensembl chr 3:12,384,655...12,409,257
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Tuba3b
tubulin, alpha 3B
decreases expression
ISO
cupric oxide results in decreased expression of TUBA3D mRNA
CTD
PMID:22077320
NCBI chr 4:178,588,779...178,594,328
Ensembl chr 4:178,588,779...178,594,326
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Tubb2b
tubulin, beta 2B class IIb
decreases expression
ISO
cupric oxide results in decreased expression of TUBB2B mRNA
CTD
PMID:22077320
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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Tubb6
tubulin, beta 6 class V
decreases expression
ISO
cupric oxide results in decreased expression of TUBB6 mRNA; cupric oxide results in decreased expression of TUBB6 protein
CTD
PMID:22077320 PMID:25470785
NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418
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Uba1
ubiquitin-like modifier activating enzyme 1
increases expression
ISO
cupric oxide results in increased expression of UBA1 protein
CTD
PMID:25470785
NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
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Ube2l3
ubiquitin-conjugating enzyme E2L 3
increases expression
ISO
cupric oxide results in increased expression of UBE2L3 protein
CTD
PMID:25470785
NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862
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Ube2t
ubiquitin-conjugating enzyme E2T
decreases expression
ISO
cupric oxide results in decreased expression of UBE2T mRNA
CTD
PMID:22077320
NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835
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Uchl1
ubiquitin C-terminal hydrolase L1
decreases activity
ISO
cupric oxide results in decreased activity of UCHL1 protein
CTD
PMID:25470785
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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Uhmk1
U2AF homology motif kinase 1
increases expression
ISO
cupric oxide results in increased expression of UHMK1 mRNA
CTD
PMID:22077320
NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
decreases expression
ISO
cupric oxide results in decreased expression of UHRF1 mRNA
CTD
PMID:22077320
NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
increases expression
ISO
cupric oxide analog results in increased expression of UQCRC1 protein
CTD
PMID:23882024
NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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Usp15
ubiquitin specific peptidase 15
increases expression
ISO
cupric oxide results in increased expression of USP15 mRNA
CTD
PMID:22077320
NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
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Usp32
ubiquitin specific peptidase 32
increases expression
ISO
cupric oxide results in increased expression of USP32 mRNA
CTD
PMID:22077320
NCBI chr10:69,855,895...70,029,075
Ensembl chr10:69,855,885...70,029,137
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Utp11
UTP11, small subunit processome component
increases expression
ISO
cupric oxide results in increased expression of UTP11 mRNA
CTD
PMID:22077320
NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191
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Utrn
utrophin
decreases expression
ISO
cupric oxide results in decreased expression of UTRN mRNA
CTD
PMID:22077320
NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
cupric oxide results in increased expression of VEGFA mRNA
CTD
PMID:22077320
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vim
vimentin
decreases expression
ISO
cupric oxide analog results in decreased expression of VIM protein
CTD
PMID:23882024
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Ybx1
Y box binding protein 1
increases expression
ISO
cupric oxide results in increased expression of YBX1 protein
CTD
PMID:25470785
NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
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Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
decreases expression
ISO
cupric oxide analog results in decreased expression of YWHAB protein
CTD
PMID:23882024
NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
decreases expression
ISO
cupric oxide analog results in decreased expression of YWHAG protein
CTD
PMID:23882024
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
decreases expression
ISO
cupric oxide results in decreased expression of YWHAH mRNA
CTD
PMID:22077320
NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
decreases expression
ISO
cupric oxide analog results in decreased expression of YWHAZ protein
CTD
PMID:23882024
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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Zbtb43
zinc finger and BTB domain containing 43
increases expression
ISO
cupric oxide results in increased expression of ZBTB43 mRNA
CTD
PMID:22077320
NCBI chr 3:16,744,535...16,763,854
Ensembl chr 3:16,744,535...16,763,909
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Zbtb5
zinc finger and BTB domain containing 5
increases expression
ISO
cupric oxide results in increased expression of ZBTB5 mRNA
CTD
PMID:22077320
NCBI chr 5:59,244,132...59,265,461
Ensembl chr 5:59,243,307...59,265,426
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Zfp110
zinc finger protein 110
increases expression
ISO
cupric oxide results in increased expression of ZNF274 mRNA
CTD
PMID:22077320
NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
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Zfp12
zinc finger protein 12
increases expression
ISO
cupric oxide results in increased expression of ZNF12 mRNA
CTD
PMID:22077320
NCBI chr12:11,316,971...11,330,498
Ensembl chr12:11,316,872...11,330,558
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Zfp143
zinc finger protein 143
increases expression
ISO
cupric oxide results in increased expression of ZNF143 mRNA
CTD
PMID:22077320
NCBI chr 1:164,109,041...164,144,902
Ensembl chr 1:164,109,116...164,144,902
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Zfp185
zinc finger protein 185
decreases expression
ISO
cupric oxide results in decreased expression of ZNF185 mRNA
CTD
PMID:22077320
NCBI chr X:150,831,869...150,877,652
Ensembl chr X:150,831,862...150,874,810
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Zfp236
zinc finger protein 236
increases expression
ISO
cupric oxide results in increased expression of ZNF236 mRNA
CTD
PMID:22077320
NCBI chr18:75,976,478...76,072,428
Ensembl chr18:75,978,231...76,073,737
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Zfp277
zinc finger protein 277
increases expression
ISO
cupric oxide results in increased expression of ZNF277 mRNA
CTD
PMID:22077320
NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765
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Zfp286a
zinc finger protein 286A
increases expression
ISO
cupric oxide results in increased expression of ZNF286A mRNA
CTD
PMID:22077320
NCBI chr10:47,450,469...47,461,267
Ensembl chr10:47,450,469...47,463,258
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Zfp34
zinc finger protein 34
increases expression
ISO
cupric oxide results in increased expression of ZNF34 mRNA
CTD
PMID:22077320
NCBI chr 5:157,509,762...157,513,970
Ensembl chr 5:157,509,451...157,599,926
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Zfp35
zinc finger protein 35
increases expression
ISO
cupric oxide results in increased expression of ZNF79 mRNA
CTD
PMID:22077320
NCBI chr18:15,268,852...15,284,334
Ensembl chr18:15,268,814...15,285,088
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Zfp36l1
zinc finger protein 36, C3H type-like 1
decreases expression
ISO
cupric oxide results in decreased expression of ZFP36L1 mRNA
CTD
PMID:22077320
NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
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Zfp36l2
zinc finger protein 36, C3H type-like 2
decreases expression
ISO
cupric oxide results in decreased expression of ZFP36L2 mRNA
CTD
PMID:22077320
NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
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Zfp394
zinc finger protein 394
increases expression
ISO
cupric oxide results in increased expression of ZNF394 mRNA
CTD
PMID:22077320
NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246
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Zfp46
zinc finger protein 46
increases expression
ISO
cupric oxide results in increased expression of ZNF436 mRNA
CTD
PMID:22077320
NCBI chr 5:148,519,398...148,529,903
Ensembl chr 5:148,520,855...148,529,459
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Zfp473
zinc finger protein 473
increases expression
ISO
cupric oxide results in increased expression of ZNF473 mRNA
CTD
PMID:22077320
NCBI chr 1:95,222,683...95,243,328
Ensembl chr 1:95,223,433...95,243,325
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Zfp507
zinc finger protein 507
increases expression
ISO
cupric oxide results in increased expression of ZNF507 mRNA
CTD
PMID:22077320
NCBI chr 1:88,435,787...88,468,577
Ensembl chr 1:88,438,246...88,468,518
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Zfp512
zinc finger protein 512
increases expression
ISO
cupric oxide results in increased expression of ZNF512 mRNA
CTD
PMID:22077320
NCBI chr 6:24,976,903...25,007,913
Ensembl chr 6:24,976,906...25,007,819
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Zfp560
zinc finger protein 560
increases expression
ISO
cupric oxide results in increased expression of ZNF121 mRNA
CTD
PMID:22077320
NCBI chr 8:18,900,142...18,914,444
Ensembl chr 8:18,900,528...18,914,442
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Zfp707
zinc finger protein 707
increases expression
ISO
cupric oxide results in increased expression of ZNF707 mRNA
CTD
PMID:22077320
NCBI chr 7:107,679,597...107,686,556
Ensembl chr 7:107,650,217...107,703,459
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Zfp719
zinc finger protein 719
increases expression
ISO
cupric oxide results in increased expression of ZNF175 mRNA
CTD
PMID:22077320
NCBI chr 1:94,009,957...94,027,342
Ensembl chr 1:93,992,492...94,023,023
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Zfp84
zinc finger protein 84
increases expression
ISO
cupric oxide results in increased expression of ZNF565 mRNA
CTD
PMID:22077320
NCBI chr 1:84,987,352...85,015,478
Ensembl chr 1:85,004,920...85,015,478 Ensembl chr 1:85,004,920...85,015,478
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Znf780b
zinc finger protein 780B
increases expression
ISO
cupric oxide results in increased expression of ZNF780B mRNA
CTD
PMID:22077320
NCBI chr 1:83,009,174...83,030,463
Ensembl chr 1:83,009,189...83,082,107
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Znf8
zinc finger protein 8
increases expression
ISO
cupric oxide results in increased expression of ZNF8 mRNA
CTD
PMID:22077320
NCBI chr 1:73,498,526...73,511,929
Ensembl chr 1:73,498,491...73,511,119
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Zranb2
zinc finger RANBP2-type containing 2
increases expression
ISO
cupric oxide results in increased expression of ZRANB2 mRNA
CTD
PMID:22077320
NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942
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Zrsr2
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2
increases expression
ISO
cupric oxide results in increased expression of ZRSR2 mRNA
CTD
PMID:22077320
NCBI chr X:30,547,424...30,571,613
Ensembl chr X:30,547,536...30,570,125
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Zscan2
zinc finger and SCAN domain containing 2
increases expression
ISO
cupric oxide results in increased expression of ZSCAN2 mRNA
CTD
PMID:22077320
NCBI chr 1:134,833,701...134,848,957
Ensembl chr 1:134,833,871...134,848,952
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Zscan20
zinc finger and SCAN domain containing 20
increases expression
ISO
cupric oxide results in increased expression of ZSCAN20 mRNA
CTD
PMID:22077320
NCBI chr 5:140,926,596...140,956,285
Ensembl chr 5:140,930,689...140,956,336
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