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Accession:CHEBI:472805 term browser browse the term
Definition:A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.
Synonyms:exact_synonym: 3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide
 related_synonym: 3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide;   Formula=C29H44O12;   G-Strophanthin;   InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1;   InChIKey=LPMXVESGRSUGHW-HBYQJFLCSA-N;   Ouabagenin L-Rhamnoside;   Ouabagenin-L-rhamnosid;   Ouabain anhydrous;   Ouabaine;   Oubain;   SMILES=[H][C@@]12CC[C@]3(O)C[C@H](C[C@@H](O)[C@]3(CO)[C@@]1([H])[C@H](O)C[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O;   Strodival
 alt_id: CHEBI:44461;   CHEBI:7805
 xref: Beilstein:101712 "Beilstein";   CAS:630-60-4 "ChemIDplus";   CAS:630-60-4 "KEGG COMPOUND";   DrugBank:DB01092;   Drug_Central:2004 "DrugCentral";   HMDB:HMDB0015224;   KEGG:C01443;   KEGG:D00112;   KNApSAcK:C00003633;   LINCS:LSM-2781;   LIPID_MAPS_instance:LMST01120022 "LIPID MAPS"
 xref_mesh: MESH:D010042
 xref: PDBeChem:OBN;   PMID:10438974 "Europe PMC";   PMID:1316269 "Europe PMC";   PMID:16529963 "Europe PMC";   PMID:20372980 "Europe PMC";   PMID:9872395 "Europe PMC";   Reaxys:101712 "Reaxys";   Wikipedia:Ouabain

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ouabain term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464

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  CHEBI ontology 223
    role 223
      biological role 223
        molecular messenger 50
          hormone 30
            steroid hormone 11
              ouabain 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            heteroorganic entity 198
                              organochalcogen compound 168
                                organooxygen compound 167
                                  carbohydrates and carbohydrate derivatives 38
                                    carbohydrate 38
                                      carbohydrate derivative 33
                                        glycosyl compound 29
                                          glycoside 24
                                            deoxy hexoside 6
                                              rhamnoside 1
                                                alpha-L-rhamnoside 1
                                                  ouabain 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.