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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dyclonine
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Accession:CHEBI:4724 term browser browse the term
Definition:N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.
Synonyms:exact_synonym: 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
 related_synonym: 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone;   2-(1-piperidyl)ethyl p-butoxyphenyl ketone;   3-piperidino-4'-butoxypropiophenone;   4'-butoxy-3-piperidinopropiophenone;   4-butoxy-beta-piperidinopropiophenone;   4-n-butoxy-beta-(1-piperidyl)propiophenone;   Formula=C18H27NO2;   InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3;   InChIKey=BZEWSEKUUPWQDQ-UHFFFAOYSA-N;   SMILES=CCCCOc1ccc(cc1)C(=O)CCN1CCCCC1;   diclonina;   dycloninum
 xref: Beilstein:224037;   CAS:586-60-7;   DrugBank:DB00645;   Drug_Central:974;   KEGG:D07881;   LINCS:LSM-5801
 xref_mesh: MESH:C100063
 xref: Wikipedia:Dyclonine


show annotations for term's descendants           Sort by:
dyclonine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO dyclonine results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO dyclonine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO dyclonine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      application 19741
        pharmaceutical 19579
          drug 19579
            anaesthetic 11849
              local anaesthetic 7702
                topical anaesthetic 34
                  dyclonine 3
                    dyclonine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            heteroorganic entity 19559
                              organochalcogen compound 19317
                                organooxygen compound 19231
                                  carbonyl compound 18945
                                    ketone 17194
                                      aromatic ketone 12459
                                        dyclonine 3
                                          dyclonine hydrochloride 0
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