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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dyclonine
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Accession:CHEBI:4724 term browser browse the term
Definition:N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.
Synonyms:exact_synonym: 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
 related_synonym: 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone;   2-(1-piperidyl)ethyl p-butoxyphenyl ketone;   3-piperidino-4'-butoxypropiophenone;   4'-butoxy-3-piperidinopropiophenone;   4-butoxy-beta-piperidinopropiophenone;   4-n-butoxy-beta-(1-piperidyl)propiophenone;   Formula=C18H27NO2;   InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3;   InChIKey=BZEWSEKUUPWQDQ-UHFFFAOYSA-N;   SMILES=CCCCOc1ccc(cc1)C(=O)CCN1CCCCC1;   diclonina;   dycloninum
 xref: Beilstein:224037;   CAS:586-60-7;   DrugBank:DB00645;   Drug_Central:974;   KEGG:D07881;   LINCS:LSM-5801
 xref_mesh: MESH:C100063
 xref: Wikipedia:Dyclonine


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dyclonine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO dyclonine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO dyclonine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            anaesthetic 5284
              local anaesthetic 3042
                topical anaesthetic 29
                  dyclonine 2
                    dyclonine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      ketone 16171
                                        aromatic ketone 11909
                                          dyclonine 2
                                            dyclonine hydrochloride 0
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