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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dyclonine
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Accession:CHEBI:4724 term browser browse the term
Definition:N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.
Synonyms:exact_synonym: 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one
 related_synonym: 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone;   2-(1-piperidyl)ethyl p-butoxyphenyl ketone;   3-piperidino-4'-butoxypropiophenone;   4'-butoxy-3-piperidinopropiophenone;   4-butoxy-beta-piperidinopropiophenone;   4-n-butoxy-beta-(1-piperidyl)propiophenone;   Formula=C18H27NO2;   InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3;   InChIKey=BZEWSEKUUPWQDQ-UHFFFAOYSA-N;   SMILES=CCCCOc1ccc(cc1)C(=O)CCN1CCCCC1;   diclonina;   dycloninum
 xref: Beilstein:224037;   CAS:586-60-7;   DrugBank:DB00645;   Drug_Central:974;   KEGG:D07881;   LINCS:LSM-5801
 xref_mesh: MESH:C100063
 xref: Wikipedia:Dyclonine


show annotations for term's descendants           Sort by:
dyclonine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO dyclonine results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO dyclonine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO dyclonine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      application 19615
        pharmaceutical 19493
          drug 19493
            anaesthetic 11781
              local anaesthetic 7619
                topical anaesthetic 30
                  dyclonine 3
                    dyclonine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      carbon group element atom 19698
                        carbon atom 19693
                          organic molecular entity 19693
                            organic group 18902
                              organic divalent group 18884
                                organodiyl group 18884
                                  carbonyl group 18850
                                    carbonyl compound 18850
                                      ketone 17140
                                        aromatic ketone 12412
                                          dyclonine 3
                                            dyclonine hydrochloride 0
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