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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:DuP 697
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Accession:CHEBI:4720 term browser browse the term
Definition:A thiophene that has formula C17H12BrFO2S2.
Synonyms:related_synonym: Formula=C17H12BrFO2S2;   InChI=1S/C17H12BrFO2S2/c1-23(20,21)14-8-4-11(5-9-14)15-10-16(18)22-17(15)12-2-6-13(19)7-3-12/h2-10H,1H3;   InChIKey=AJFTZWGGHJXZOB-UHFFFAOYSA-N;   SMILES=CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
 xref: CAS:88149-94-4;   KEGG:C11704;   LINCS:LSM-2119
 xref_mesh: MESH:C064874


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DuP 697 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO DuP 697 inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein] CTD PMID:21163909 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
EXP
ISO
[DuP 697 results in decreased expression of PTGS2] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of Dinoprostone]
DuP 697 results in decreased activity of PTGS2 protein
CTD PMID:19397918 PMID:25451575 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO DuP 697 results in increased expression of TNFRSF10A protein CTD PMID:15572759 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Vegfa vascular endothelial growth factor A affects secretion ISO DuP 697 affects the secretion of VEGFA protein CTD PMID:15705899 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      atom 19772
        nonmetal atom 19651
          sulfur atom 16301
            sulfur molecular entity 16301
              organosulfur compound 15245
                organosulfur heterocyclic compound 5857
                  thiophenes 200
                    DuP 697 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic molecule 19502
                              organic cyclic compound 19329
                                organic heterocyclic compound 18544
                                  organosulfur heterocyclic compound 5857
                                    thiophenes 200
                                      DuP 697 4
paths to the root