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G |
Abat |
4-aminobutyrate aminotransferase |
decreases expression |
EXP |
1-bromopropane results in decreased expression of ABAT protein |
CTD |
PMID:21925529 |
|
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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G |
Anp32a |
acidic nuclear phosphoprotein 32 family member A |
increases expression |
EXP |
1-bromopropane results in increased expression of ANP32A protein |
CTD |
PMID:21925529 |
|
NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443
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G |
Arg1 |
arginase 1 |
increases expression multiple interactions |
EXP |
1-bromopropane results in increased expression of ARG1 protein allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of ARG1 protein] |
CTD |
PMID:30247689 |
|
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression |
EXP |
1-bromopropane results in decreased expression of ATP5PD protein |
CTD |
PMID:21925529 |
|
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
EXP ISO |
1-bromopropane results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:16815550 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions decreases expression |
ISO EXP |
1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein] 1-bromopropane results in decreased expression of BDNF mRNA |
CTD |
PMID:19189864 PMID:23266320 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Casp3 |
caspase 3 |
increases cleavage |
EXP |
1-bromopropane results in increased cleavage of CASP3 protein |
CTD |
PMID:30247689 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cat |
catalase |
decreases expression |
EXP |
1-bromopropane results in decreased expression of CAT mRNA |
CTD |
PMID:27452781 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccn5 |
cellular communication network factor 5 |
multiple interactions increases expression |
ISO |
ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CCN5 mRNA] |
CTD |
PMID:23384675 |
|
NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
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G |
Ckb |
creatine kinase B |
decreases expression |
EXP |
1-bromopropane results in decreased expression of CKB protein |
CTD |
PMID:21925529 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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|
G |
Ckmt1 |
creatine kinase, mitochondrial 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of CKMT1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
1-bromopropane results in decreased phosphorylation of and results in decreased activity of CREB1 protein |
CTD |
PMID:19189864 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression multiple interactions |
ISO |
1-bromopropane results in increased expression of CXCL12 mRNA ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA] |
CTD |
PMID:23384675 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cybb |
cytochrome b-245 beta chain |
increases expression |
EXP |
1-bromopropane results in increased expression of CYBB mRNA; 1-bromopropane results in increased expression of CYBB protein |
CTD |
PMID:27452781 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases response to substance multiple interactions increases expression |
ISO EXP |
CYP2E1 protein results in increased susceptibility to 1-bromopropane allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1] |
CTD |
PMID:19638432 PMID:30247689 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Drd1 |
dopamine receptor D1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of DRD1 mRNA |
CTD |
PMID:19576243 |
|
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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G |
Drd2 |
dopamine receptor D2 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of DRD2 mRNA |
CTD |
PMID:19576243 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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G |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of ECH1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CCN5 mRNA]; ESR1 protein inhibits the reaction [1-bromopropane results in increased expression of CXCL12 mRNA] |
CTD |
PMID:23384675 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
increases expression |
ISO |
1-bromopropane results in increased expression of ESR2 protein alternative form |
CTD |
PMID:27634370 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Gabra1 |
gamma-aminobutyric acid type A receptor subunit alpha 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of GABRA1 mRNA |
CTD |
PMID:19576243 |
|
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
increases expression |
EXP |
1-bromopropane results in increased expression of GABRG2 mRNA |
CTD |
PMID:19576243 |
|
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions |
ISO |
1-bromopropane results in increased expression of GCLC mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLC mRNA] |
CTD |
PMID:20211940 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA] |
CTD |
PMID:20211940 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gda |
guanine deaminase |
decreases expression |
EXP |
1-bromopropane results in decreased expression of GDA protein |
CTD |
PMID:21925529 |
|
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity |
ISO |
1-bromopropane results in increased activity of GPT protein |
CTD |
PMID:17265426 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
increases expression |
EXP |
1-bromopropane results in increased expression of GRIA1 mRNA |
CTD |
PMID:32715571 |
|
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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G |
Gsr |
glutathione-disulfide reductase |
increases expression decreases activity multiple interactions |
ISO EXP |
1-bromopropane results in increased expression of GSR mRNA 1-bromopropane results in decreased activity of GSR protein NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GSR mRNA] |
CTD |
PMID:20211940 PMID:23395825 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
increases expression |
EXP |
1-bromopropane results in increased expression of GSTA3 protein |
CTD |
PMID:21925529 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gstp1 |
glutathione S-transferase pi 1 |
increases expression |
EXP |
1-bromopropane results in increased expression of GSTP1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
1-bromopropane results in increased expression of HMOX1 mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of HMOX1 mRNA] |
CTD |
PMID:20211940 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of HNRNPH1 protein |
CTD |
PMID:21925529 |
|
NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP ISO |
1-bromopropane results in increased expression of HSPA5 protein |
CTD |
PMID:21925529 PMID:27421776 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
increases expression |
EXP |
1-bromopropane results in increased expression of HSPD1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
decreases expression |
EXP |
1-bromopropane results in decreased expression of HTR1A mRNA |
CTD |
PMID:19576243 |
|
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
decreases expression |
EXP |
1-bromopropane results in decreased expression of HTR2A mRNA |
CTD |
PMID:19576243 |
|
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Htr2c |
5-hydroxytryptamine receptor 2C |
increases expression |
EXP |
1-bromopropane results in increased expression of HTR2C mRNA |
CTD |
PMID:19576243 |
|
NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
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G |
Htr3a |
5-hydroxytryptamine receptor 3A |
affects expression |
EXP |
1-bromopropane affects the expression of HTR3A mRNA |
CTD |
PMID:19576243 |
|
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases secretion increases expression |
ISO |
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] 1-bromopropane results in increased secretion of IL1B protein 1-bromopropane results in increased expression of IL1B mRNA |
CTD |
PMID:16815550 PMID:18164123 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases secretion increases expression |
ISO |
1-bromopropane results in increased secretion of IL6 protein 1-bromopropane results in increased expression of IL6 mRNA |
CTD |
PMID:18164123 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
1-bromopropane results in increased phosphorylation of MAPK1 protein MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]] |
CTD |
PMID:18164123 PMID:22353212 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
1-bromopropane results in increased phosphorylation of MAPK3 protein MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]] |
CTD |
PMID:18164123 PMID:22353212 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions decreases response to substance decreases expression |
ISO EXP |
NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLC mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GSR mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of HMOX1 mRNA]; NFE2L2 promotes the reaction [1-bromopropane results in increased expression of NQO1 mRNA] NFE2L2 results in decreased susceptibility to 1-bromopropane 1-bromopropane results in decreased expression of NFE2L2 mRNA |
CTD |
PMID:20211940 PMID:27452781 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] 1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]; MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]; MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]] |
CTD |
PMID:16815550 PMID:18164123 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions increases degradation |
ISO |
1-bromopropane inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] 1-bromopropane results in increased degradation of NFKBIA protein |
CTD |
PMID:16815550 PMID:18164123 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of NOS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [1-bromopropane results in increased expression of NOS2 mRNA] allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of NOS2 protein] |
CTD |
PMID:18164123 PMID:30247689 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
1-bromopropane results in increased expression of NQO1 mRNA NFE2L2 promotes the reaction [1-bromopropane results in increased expression of NQO1 mRNA] |
CTD |
PMID:20211940 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of NR3C1 mRNA |
CTD |
PMID:23266320 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Park7 |
Parkinsonism associated deglycase |
decreases expression |
EXP |
1-bromopropane results in decreased expression of PARK7 protein |
CTD |
PMID:21925529 |
|
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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G |
Phgdh |
phosphoglycerate dehydrogenase |
increases expression |
EXP |
1-bromopropane results in increased expression of PHGDH protein |
CTD |
PMID:21925529 |
|
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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G |
Pmpcb |
peptidase, mitochondrial processing subunit beta |
decreases expression |
EXP |
1-bromopropane results in decreased expression of PMPCB protein |
CTD |
PMID:21925529 |
|
NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367
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G |
Psma1 |
proteasome 20S subunit alpha 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of PSMA1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
1-bromopropane results in increased expression of and results in increased activity of PTGS2 protein; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [1-bromopropane results in increased expression of PTGS2 protein] 1-bromopropane results in increased expression of PTGS2 mRNA |
CTD |
PMID:22353212 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ran |
RAN, member RAS oncogene family |
increases expression |
EXP ISO |
1-bromopropane results in increased expression of RAN protein |
CTD |
PMID:21925529 PMID:27421776 |
|
NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
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G |
Rbfox3 |
RNA binding fox-1 homolog 3 |
multiple interactions increases expression |
EXP |
allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of RBFOX3 protein] |
CTD |
PMID:30247689 |
|
NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization |
ISO EXP |
1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] 1-bromopropane inhibits the reaction [IL1B protein results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]; 1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]; MAPK1 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]]; MAPK3 protein affects the reaction [1-bromopropane results in increased activity of [NFKB1 protein binds to RELA protein]] 1-bromopropane affects the localization of RELA protein 1-bromopropane results in increased phosphorylation of and results in increased activity of RELA protein; allyl sulfide inhibits the reaction [1-bromopropane results in increased phosphorylation of and results in increased activity of RELA protein] |
CTD |
PMID:16815550 PMID:18164123 PMID:30247689 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Scn1a |
sodium voltage-gated channel alpha subunit 1 |
increases expression |
EXP |
1-bromopropane results in increased expression of SCN1A mRNA |
CTD |
PMID:32715571 |
|
NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
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G |
Sod1 |
superoxide dismutase 1 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of SOD1 mRNA |
CTD |
PMID:27452781 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
EXP |
1-bromopropane results in decreased expression of SOD2 mRNA |
CTD |
PMID:27452781 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Tnf |
tumor necrosis factor |
increases expression increases secretion |
ISO |
1-bromopropane results in increased expression of TNF mRNA 1-bromopropane results in increased secretion of TNF protein |
CTD |
PMID:18164123 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tpi1 |
triosephosphate isomerase 1 |
increases expression decreases expression |
EXP |
1-bromopropane results in increased expression of TPI1 protein 1-bromopropane results in decreased expression of TPI1 protein |
CTD |
PMID:21925529 |
|
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
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