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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzoxazine
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Accession:CHEBI:46969 term browser browse the term
Synonyms:related_synonym: benzoxazines


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cetilistat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression ISO cetilistat results in decreased expression of HBA1 protein modified form CTD PMID:19461584 NCBI chr10:15,323,830...15,324,677 JBrowse link
efavirenz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO efavirenz inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
efavirenz results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
decreases secretion
ISO efavirenz results in decreased expression of ADIPOQ mRNA
efavirenz results in decreased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alb albumin affects binding ISO efavirenz binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bcl2l11 BCL2 like 11 increases response to substance
increases expression
ISO BCL2L11 protein results in increased susceptibility to efavirenz metabolite
efavirenz metabolite results in increased expression of BCL2L11 mRNA; efavirenz metabolite results in increased expression of BCL2L11 protein; efavirenz results in increased expression of BCL2L11 mRNA; efavirenz results in increased expression of BCL2L11 protein
CTD PMID:21958719 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Canx calnexin affects localization ISO efavirenz affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp3 caspase 3 multiple interactions ISO efavirenz metabolite results in increased cleavage of and results in increased activity of CASP3 protein; efavirenz results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:21958719 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO efavirenz results in increased secretion of CCL2 protein CTD PMID:21619898 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO efavirenz results in decreased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
decreases activity
multiple interactions
increases metabolic processing
ISO CYP2B6 gene polymorphism affects the metabolism of efavirenz; CYP2B6 protein affects the metabolism of efavirenz
efavirenz results in decreased activity of CYP2B6 protein
[efavirenz results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion; [efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in increased metabolism of efavirenz
CTD PMID:15622315 PMID:15769884 PMID:17041008 PMID:17559344 PMID:26599973 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO efavirenz results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
increases expression
increases activity
ISO efavirenz results in decreased activity of CYP3A4 protein
efavirenz results in increased expression of CYP3A4 mRNA
efavirenz results in increased activity of CYP3A4 protein
CTD PMID:15980690 PMID:16837568 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO efavirenz results in increased expression of DDIT3 protein CTD PMID:28940366 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnm1l dynamin 1-like affects localization ISO efavirenz affects the localization of DNM1L protein modified form CTD PMID:28940366 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO efavirenz results in increased expression of EIF2AK3 protein modified form CTD PMID:28940366 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO efavirenz results in increased expression of FIS1 mRNA CTD PMID:28940366 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Hgf hepatocyte growth factor increases secretion ISO efavirenz results in increased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Il6 interleukin 6 increases secretion ISO efavirenz results in increased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of JUN protein; efavirenz results in increased phosphorylation of JUN protein CTD PMID:21958719 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lep leptin decreases expression ISO efavirenz results in decreased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial multiple interactions
increases expression
increases response to substance
ISO efavirenz results in increased expression of and affects the localization of LONP1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [efavirenz results in increased expression of LONP1 mRNA]
LONP1 protein results in increased susceptibility to efavirenz
CTD PMID:28940366 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO efavirenz results in decreased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of MAP3K5 protein; efavirenz results in increased phosphorylation of MAP3K5 protein CTD PMID:21958719 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]
efavirenz metabolite results in increased phosphorylation of MAPK8 protein; efavirenz results in increased phosphorylation of MAPK8 protein
CTD PMID:21958719 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO efavirenz results in increased expression of MFN2 mRNA CTD PMID:28940366 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity EXP efavirenz results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity
ISO
EXP
[efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 PMID:27732639 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression ISO efavirenz results in increased expression of OPA1 mRNA CTD PMID:28940366 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO efavirenz results in decreased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 increases expression ISO efavirenz results in increased expression of RMDN3 protein CTD PMID:28940366 NCBI chr 3:106,125,961...106,146,568
Ensembl chr 3:106,125,951...106,146,586
JBrowse link
G Serpine1 serpin family E member 1 increases secretion ISO efavirenz results in increased secretion of SERPINE1 protein CTD PMID:21619898 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tg thyroglobulin increases expression ISO efavirenz results in increased expression of TG mRNA; efavirenz results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tpo thyroid peroxidase increases expression ISO efavirenz results in increased expression of TPO mRNA; efavirenz results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein; efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO efavirenz results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
olodaterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 multiple interactions
affects expression
increases expression
ISO Cycloheximide inhibits the reaction [olodaterol affects the expression of ADRB2 mRNA]; EDN1 protein promotes the reaction [olodaterol results in increased expression of ADRB2 mRNA]; ICI 118551 inhibits the reaction [olodaterol affects the expression of ADRB2 mRNA]; olodaterol promotes the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] CTD PMID:22483689 PMID:24705868 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Edn1 endothelin 1 multiple interactions
decreases expression
ISO 2'-O-methyl-8-(4-chlorophenylthio)cAMP inhibits the reaction [olodaterol results in decreased expression of EDN1 mRNA]; EDN1 protein promotes the reaction [olodaterol results in increased expression of ADRB2 mRNA]; ICI 118551 inhibits the reaction [olodaterol results in decreased expression of EDN1 mRNA]; N(6)-benzyl-cyclic adenosine 5'-monophosphate inhibits the reaction [olodaterol results in decreased expression of EDN1 mRNA]; olodaterol inhibits the reaction [Oxotremorine results in increased expression of EDN1 mRNA]; olodaterol inhibits the reaction [TGFB1 protein results in increased expression of EDN1 mRNA]; olodaterol promotes the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] CTD PMID:22483689 PMID:22796455 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO olodaterol inhibits the reaction [TGFB1 protein results in increased expression of EDN1 mRNA] CTD PMID:22796455 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          nitrogen atom 18765
            nitrogen molecular entity 18765
              organonitrogen compound 18538
                organonitrogen heterocyclic compound 17643
                  benzoxazine 42
                    (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one 0
                    (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2H-1,4-benzoxazin-3(4H)-one 0
                    1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one 0
                    1-methyl-7-nitroisatoic anhydride 0
                    2,4-Dihydroxy-6,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one 0
                    2-(2,3,4-trimethoxyphenyl)-2,3-dihydro-1,3-benzoxazin-4-one 0
                    2-(2-ethyl-6-methyl-3-oxo-1,4-benzoxazin-4-yl)-N-[(5-methyl-2-furanyl)methyl]-N-(3-pyridinylmethyl)acetamide 0
                    2-(2-methyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)acetamide 0
                    2-(3-nitrophenyl)-3,1-benzoxazin-4-one 0
                    2-(3-thiophenyl)acetic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                    2-(5-bromo-2-furanyl)-6-methyl-3,1-benzoxazin-4-one 0
                    2-Hydroxy-4,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one 0
                    2-[2,2-dimethyl-6-[4-morpholinyl(oxo)methyl]-3-oxo-1,4-benzoxazin-4-yl]-N-phenylacetamide 0
                    2-[4-[(4-chlorophenyl)-oxomethyl]-2,3-dihydro-1,4-benzoxazin-3-yl]acetic acid methyl ester 0
                    2-hydroxy-2-phenyl-3H-1,3-benzoxazin-4-one 0
                    3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA 0
                    3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid 0
                    3-(2,6-dimethyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)propanamide 0
                    3-(2-oxopropyl)-1,4-benzoxazin-2-one 0
                    3-chloro-1-benzothiophene-2-carboxylic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                    3-methyl-N-[4-(4-oxo-3,1-benzoxazin-2-yl)phenyl]butanamide 0
                    3-phenyl-2H-1,4-benzoxazine 0
                    4-(6-chloro-2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)-4-oxo-N-(phenylmethyl)butanamide 0
                    4-(dimethylsulfamoyl)benzoic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                    4-[(3-oxo-4H-1,4-benzoxazin-7-yl)sulfonyl]-1-piperazinecarboxylic acid ethyl ester 0
                    4-[[(4-acetyl-2,3-dihydro-1,4-benzoxazin-7-yl)sulfonylamino]methyl]-N-(3-methylphenyl)-1-cyclohexanecarboxamide 0
                    6-(2,4-diamino-6-ethylpyrimidin-5-yl)-4-(3-methoxypropyl)-2,2-dimethyl-2H-1,4-benzoxazin-3(4H)-one 0
                    6-[1-oxo-2-[[4-(phenylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]ethyl]-4H-1,4-benzoxazin-3-one 0
                    6-[2-(2-methoxyphenyl)imino-3-(2-oxolanylmethyl)-4-thiazolyl]-4H-1,4-benzoxazin-3-one 0
                    6-[2-butylimino-3-(cyclopentylideneamino)-4-thiazolyl]-4H-1,4-benzoxazin-3-one 0
                    6-bromo-N-(3,4-dimethylphenyl)-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                    6-chloro-3-(3,3-dimethyl-2-oxobutyl)-1,4-benzoxazin-2-one 0
                    6-chloro-3-(4-methyl-2-oxopentyl)-1,4-benzoxazin-2-one 0
                    6-chloro-3-[2-(2-furanyl)-2-oxoethyl]-1,4-benzoxazin-2-one 0
                    6-chloro-N-(3,4-dimethylphenyl)-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                    6-hydroxy-2-(4-nitrophenyl)-3,1-benzoxazin-4-one 0
                    Avenalumin II 0
                    Avenalumin III 0
                    Azasetron hydrochloride 0
                    Benoxacor 0
                    DIBOA + 0
                    DIMBOA + 0
                    DIMBOA glucoside + 0
                    Dianthalexin 0
                    HBOA + 0
                    HMBOA beta-D-glucoside 0
                    LSM-11779 0
                    LSM-33653 0
                    LSM-33656 0
                    N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide 0
                    N-(3,5-dimethoxyphenyl)-6-methyl-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                    N-[(1S)-1-(1H-benzimidazol-2-yl)-2-\{4-[(5S)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide 0
                    N-[(4-fluorophenyl)methyl]-2-[3-oxo-6-(1-piperidinylsulfonyl)-1,4-benzoxazin-4-yl]acetamide 0
                    N-[(4-tert-butylphenyl)methyl]-3-oxo-4H-1,4-benzoxazine-6-carboxamide 0
                    N-[2-(\{2-amino-6-ethyl-5-[4-(3-methoxypropyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl]pyrimidin-4-yl\}amino)ethyl]naphthalene-2-sulfonamide 0
                    N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-2-(3-oxo-1,4-benzoxazin-4-yl)acetamide 0
                    N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-3-(3-oxo-1,4-benzoxazin-4-yl)propanamide 0
                    N-[4-(4-oxo-2,3-dihydro-1,3-benzoxazin-2-yl)phenyl]acetamide 0
                    N-\{2-[6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl]ethyl\}acetamide 0
                    N-butyl-4-[(4-methyl-3-oxo-1,4-benzoxazin-2-ylidene)methyl]benzamide 0
                    N-methylisatoic anhydride 0
                    TRIBOA + 0
                    TRIBOA beta-D-glucoside 0
                    acetic acid [2-(2-methylphenyl)-4-oxo-3,1-benzoxazin-7-yl] ester 0
                    acetic acid [3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester 0
                    bentranil 0
                    caroxazone 0
                    carsalam 0
                    cetilistat 1
                    chlorthenoxazine 0
                    efavirenz 38
                    etifoxine 0
                    flumioxazin 0
                    olodaterol 3
                    platensimycin B2 0
                    trifludimoxazin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  organic heteropolycyclic compound 18064
                                    organic heterobicyclic compound 16868
                                      benzoxazine 42
                                        (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one 0
                                        (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2H-1,4-benzoxazin-3(4H)-one 0
                                        1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one 0
                                        1-methyl-7-nitroisatoic anhydride 0
                                        2,4-Dihydroxy-6,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one 0
                                        2-(2,3,4-trimethoxyphenyl)-2,3-dihydro-1,3-benzoxazin-4-one 0
                                        2-(2-ethyl-6-methyl-3-oxo-1,4-benzoxazin-4-yl)-N-[(5-methyl-2-furanyl)methyl]-N-(3-pyridinylmethyl)acetamide 0
                                        2-(2-methyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)acetamide 0
                                        2-(3-nitrophenyl)-3,1-benzoxazin-4-one 0
                                        2-(3-thiophenyl)acetic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                                        2-(5-bromo-2-furanyl)-6-methyl-3,1-benzoxazin-4-one 0
                                        2-Hydroxy-4,7-dimethoxy-2H-1,4-benzoxazin-3(4H)-one 0
                                        2-[2,2-dimethyl-6-[4-morpholinyl(oxo)methyl]-3-oxo-1,4-benzoxazin-4-yl]-N-phenylacetamide 0
                                        2-[4-[(4-chlorophenyl)-oxomethyl]-2,3-dihydro-1,4-benzoxazin-3-yl]acetic acid methyl ester 0
                                        2-hydroxy-2-phenyl-3H-1,3-benzoxazin-4-one 0
                                        3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA 0
                                        3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid 0
                                        3-(2,6-dimethyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)propanamide 0
                                        3-(2-oxopropyl)-1,4-benzoxazin-2-one 0
                                        3-chloro-1-benzothiophene-2-carboxylic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                                        3-methyl-N-[4-(4-oxo-3,1-benzoxazin-2-yl)phenyl]butanamide 0
                                        3-phenyl-2H-1,4-benzoxazine 0
                                        4-(6-chloro-2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)-4-oxo-N-(phenylmethyl)butanamide 0
                                        4-(dimethylsulfamoyl)benzoic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester 0
                                        4-[(3-oxo-4H-1,4-benzoxazin-7-yl)sulfonyl]-1-piperazinecarboxylic acid ethyl ester 0
                                        4-[[(4-acetyl-2,3-dihydro-1,4-benzoxazin-7-yl)sulfonylamino]methyl]-N-(3-methylphenyl)-1-cyclohexanecarboxamide 0
                                        6-(2,4-diamino-6-ethylpyrimidin-5-yl)-4-(3-methoxypropyl)-2,2-dimethyl-2H-1,4-benzoxazin-3(4H)-one 0
                                        6-[1-oxo-2-[[4-(phenylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]ethyl]-4H-1,4-benzoxazin-3-one 0
                                        6-[2-(2-methoxyphenyl)imino-3-(2-oxolanylmethyl)-4-thiazolyl]-4H-1,4-benzoxazin-3-one 0
                                        6-[2-butylimino-3-(cyclopentylideneamino)-4-thiazolyl]-4H-1,4-benzoxazin-3-one 0
                                        6-bromo-N-(3,4-dimethylphenyl)-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                                        6-chloro-3-(3,3-dimethyl-2-oxobutyl)-1,4-benzoxazin-2-one 0
                                        6-chloro-3-(4-methyl-2-oxopentyl)-1,4-benzoxazin-2-one 0
                                        6-chloro-3-[2-(2-furanyl)-2-oxoethyl]-1,4-benzoxazin-2-one 0
                                        6-chloro-N-(3,4-dimethylphenyl)-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                                        6-hydroxy-2-(4-nitrophenyl)-3,1-benzoxazin-4-one 0
                                        Avenalumin II 0
                                        Avenalumin III 0
                                        Azasetron hydrochloride 0
                                        Benoxacor 0
                                        DIBOA + 0
                                        DIMBOA + 0
                                        DIMBOA glucoside + 0
                                        Dianthalexin 0
                                        HBOA + 0
                                        HMBOA beta-D-glucoside 0
                                        LSM-11779 0
                                        LSM-33653 0
                                        LSM-33656 0
                                        N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide 0
                                        N-(3,5-dimethoxyphenyl)-6-methyl-3-oxo-4H-1,4-benzoxazine-7-sulfonamide 0
                                        N-[(1S)-1-(1H-benzimidazol-2-yl)-2-\{4-[(5S)-1,1-dioxido-3-oxo-1,2-thiazolidin-5-yl]phenyl\}ethyl]-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide 0
                                        N-[(4-fluorophenyl)methyl]-2-[3-oxo-6-(1-piperidinylsulfonyl)-1,4-benzoxazin-4-yl]acetamide 0
                                        N-[(4-tert-butylphenyl)methyl]-3-oxo-4H-1,4-benzoxazine-6-carboxamide 0
                                        N-[2-(\{2-amino-6-ethyl-5-[4-(3-methoxypropyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl]pyrimidin-4-yl\}amino)ethyl]naphthalene-2-sulfonamide 0
                                        N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-2-(3-oxo-1,4-benzoxazin-4-yl)acetamide 0
                                        N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-3-(3-oxo-1,4-benzoxazin-4-yl)propanamide 0
                                        N-[4-(4-oxo-2,3-dihydro-1,3-benzoxazin-2-yl)phenyl]acetamide 0
                                        N-\{2-[6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl]ethyl\}acetamide 0
                                        N-butyl-4-[(4-methyl-3-oxo-1,4-benzoxazin-2-ylidene)methyl]benzamide 0
                                        N-methylisatoic anhydride 0
                                        TRIBOA + 0
                                        TRIBOA beta-D-glucoside 0
                                        acetic acid [2-(2-methylphenyl)-4-oxo-3,1-benzoxazin-7-yl] ester 0
                                        acetic acid [3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester 0
                                        bentranil 0
                                        caroxazone 0
                                        carsalam 0
                                        cetilistat 1
                                        chlorthenoxazine 0
                                        efavirenz 38
                                        etifoxine 0
                                        flumioxazin 0
                                        olodaterol 3
                                        platensimycin B2 0
                                        trifludimoxazin 0
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