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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:capsaicinoid
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Accession:CHEBI:46931 term browser browse the term
Definition:A family of aromatic fatty amides produced as secondary metabolites by chilli peppers.
Synonyms:related_synonym: capsaicinoids


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capsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression
increases response to substance		 ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; [Capsaicin results in increased expression of ABCA1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in increased expression of ABCA1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Cyclosporine affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; KT 5720 inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]
ABCA1 results in increased susceptibility to Capsaicin		 CTD PMID:21908651 NCBI chr 5:72,473,676...72,596,563 JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of ABCB1 mRNA; Capsaicin results in increased expression of ABCB1 protein
Capsaicin results in decreased expression of ABCB1A mRNA
Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]		 CTD PMID:16674925 PMID:24013073 NCBI chr 4:26,312,403...26,488,456 JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression EXP Capsaicin results in decreased expression of ABCB1B mRNA CTD PMID:24013073 NCBI chr 4:26,197,706...26,280,156 JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Capsaicin results in increased expression of ABL1 mRNA CTD PMID:19502594 NCBI chr 3:35,377,587...35,480,843 JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression EXP Capsaicin results in decreased expression of ACACB mRNA CTD PMID:16278290 NCBI chr12:48,026,394...48,138,214 JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Capsaicin results in increased expression of ACOX1 mRNA CTD PMID:18533110 NCBI chr10:101,905,083...101,930,136 JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Capsaicin results in decreased expression of ACSL3 mRNA CTD PMID:18533110 NCBI chr 9:80,115,164...80,164,636 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion
increases expression		 ISO Capsaicin results in increased secretion of ADIPOQ protein
Capsaicin results in increased expression of ADIPOQ mRNA; Capsaicin results in increased expression of ADIPOQ protein		 CTD PMID:17295509 PMID:17719033 PMID:19798065 NCBI chr11:91,226,524...91,240,244 JBrowse link
G Adra2a adrenoceptor alpha 2A decreases response to substance ISO ADRA2A results in decreased susceptibility to Capsaicin CTD PMID:15220790 NCBI chr 1:263,066,780...263,069,580 JBrowse link
G Aga aspartylglucosaminidase decreases expression EXP Capsaicin results in decreased expression of AGA mRNA CTD PMID:16278290 NCBI chr16:38,504,661...38,516,607 JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Capsaicin results in increased expression of AGTR1A mRNA CTD PMID:20349343 NCBI chr17:34,383,397...34,435,523 JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein] CTD PMID:21250977 NCBI chr 6:57,961,423...57,998,901 JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO Capsaicin affects the localization of AIFM1 protein CTD PMID:20925121 NCBI chr  X:132,528,107...132,567,237 JBrowse link
G Akirin2 akirin 2 increases expression EXP Capsaicin results in increased expression of AKIRIN2 mRNA CTD PMID:16278290 NCBI chr 5:49,108,231...49,122,566 JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR1A1 protein] CTD PMID:20359164 NCBI chr 5:135,329,605...135,367,037 JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR7A3 protein] CTD PMID:20359164 NCBI chr 5:151,590,968...151,601,394 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
increases phosphorylation
multiple interactions
increases activity		 EXP
ISO		 Capsaicin results in increased expression of AKT1 protein modified form
Capsaicin results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein]; [Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein
Capsaicin results in increased activity of AKT1 protein		 CTD PMID:16360265 PMID:17084039 PMID:17979524 PMID:19011674 PMID:19059400 More... NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Alb albumin increases expression ISO Capsaicin results in increased expression of ALB protein CTD PMID:9537786 PMID:18991268 NCBI chr14:17,891,564...17,907,043 JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 decreases expression EXP Capsaicin results in decreased expression of ALDH3A1 mRNA CTD PMID:16278290 NCBI chr10:46,392,464...46,402,151 JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity		 EXP [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein
Capsaicin results in decreased activity of ALOX5 protein		 CTD PMID:16956363 NCBI chr 4:151,203,948...151,251,126 JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 decreases expression EXP Capsaicin results in decreased expression of AMHR2 mRNA CTD PMID:16278290 NCBI chr 7:135,454,517...135,470,183 JBrowse link
G Amn amnion associated transmembrane protein multiple interactions
increases expression		 EXP AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]
Capsaicin results in increased expression of AMN protein		 CTD PMID:16938409 NCBI chr 6:136,132,567...136,140,008 JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Capsaicin results in increased expression of ANGPT1 mRNA CTD PMID:21310942 NCBI chr 7:75,415,959...75,668,696 JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Capsaicin results in increased expression of ANGPT2 mRNA CTD PMID:21310942 NCBI chr16:71,088,364...71,138,805 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Capsaicin results in increased expression of APAF1 mRNA CTD PMID:19502594 NCBI chr 7:27,381,392...27,466,772 JBrowse link
G Apob apolipoprotein B increases expression EXP Capsaicin results in increased expression of APOB mRNA CTD PMID:16278290 NCBI chr 6:36,563,704...36,603,300 JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Capsaicin results in decreased expression of APOC1 mRNA CTD PMID:18533110 NCBI chr 1:79,347,057...79,350,340 JBrowse link
G Apoe apolipoprotein E multiple interactions ISO APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Cholesterol]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Triglycerides] CTD PMID:21908651 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Aqp1 aquaporin 1 increases response to substance ISO AQP1 results in increased susceptibility to Capsaicin CTD PMID:20018876 NCBI chr 4:85,812,784...85,824,964 JBrowse link
G Ar androgen receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of AR protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of AR protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of AR protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of AR protein]		 CTD PMID:16540674 PMID:19059400 NCBI chr  X:63,104,771...63,273,934 JBrowse link
G Areg amphiregulin multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] CTD PMID:20660715 NCBI chr14:17,256,384...17,265,641 JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP Capsaicin results in increased expression of ARPP19 mRNA CTD PMID:16278290 NCBI chr 8:75,779,640...75,802,474 JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO Capsaicin results in decreased expression of ARRDC4 mRNA CTD PMID:33512557 NCBI chr 1:122,369,355...122,383,351 JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein] CTD PMID:20110283 NCBI chr13:105,274,103...105,331,653 JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
affects localization
increases expression		 ISO Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein]
Capsaicin affects the localization of ATF4 protein		 CTD PMID:18533110 PMID:19139269 PMID:20925121 NCBI chr 7:113,684,681...113,686,739 JBrowse link
G Atg16l1 autophagy related 16-like 1 decreases expression EXP Capsaicin results in decreased expression of ATG16L1 mRNA CTD PMID:20349343 NCBI chr 9:95,869,839...95,905,354 JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression		 ISO ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]
Capsaicin results in increased expression of ATG5 protein		 CTD PMID:22226932 NCBI chr20:49,380,835...49,471,826 JBrowse link
G Atm ATM serine/threonine kinase increases activity
multiple interactions
increases phosphorylation
increases expression		 ISO Capsaicin results in increased activity of ATM protein
3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein
Capsaicin results in increased phosphorylation of ATM protein
Capsaicin results in increased expression of ATM mRNA		 CTD PMID:19502594 PMID:22226932 NCBI chr 8:62,724,939...62,829,040 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects metabolic processing
decreases expression		 EXP Capsaicin affects the metabolism of ATP2A2 protein
Capsaicin results in decreased expression of ATP2A2 protein modified form		 CTD PMID:18037908 NCBI chr12:34,072,710...34,122,142 JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 decreases expression EXP Capsaicin results in decreased expression of ATP6AP1 mRNA CTD PMID:16278290 NCBI chr  X:157,231,243...157,238,323 JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Capsaicin results in increased expression of BAD mRNA CTD PMID:19502594 NCBI chr 1:213,562,719...213,572,034 JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO Capsaicin results in increased expression of BAG3 mRNA CTD PMID:19502594 NCBI chr 1:192,533,460...192,557,281 JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases expression		 ISO Capsaicin results in increased activity of BAK1 protein
Capsaicin results in increased expression of BAK1 mRNA		 CTD PMID:17295509 PMID:19502594 NCBI chr20:5,102,334...5,111,615 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
affects localization
increases activity		 ISO TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
Capsaicin affects the expression of BAX protein
Capsaicin results in increased expression of BAX; Capsaicin results in increased expression of BAX mRNA; Capsaicin results in increased expression of BAX protein
Capsaicin affects the localization of BAX protein
Capsaicin results in increased activity of BAX protein		 CTD PMID:16540674 PMID:17292493 PMID:17295509 PMID:19002586 PMID:19331147 More... NCBI chr 1:105,076,472...105,081,906 JBrowse link
G Bcan brevican decreases expression EXP Capsaicin results in decreased expression of BCAN mRNA CTD PMID:16278290 NCBI chr 2:173,454,479...173,467,717 JBrowse link
G Bcl10 BCL10, immune signaling adaptor increases expression ISO Capsaicin results in increased expression of BCL10 mRNA CTD PMID:19502594 NCBI chr 2:237,501,181...237,510,821 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
affects expression
increases expression
decreases expression		 ISO BCL2 protein results in decreased susceptibility to Capsaicin
Capsaicin affects the expression of BCL2 protein
Capsaicin results in increased expression of BCL2 mRNA
Capsaicin results in decreased expression of BCL2 protein
Capsaicin results in decreased expression of BCL2; Capsaicin results in decreased expression of BCL2 protein		 CTD PMID:9580328 PMID:11275362 PMID:15595419 PMID:17295509 PMID:17306913 More... NCBI chr13:23,204,464...23,366,900 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BCL2L1 protein
Capsaicin results in increased expression of BCL2L1 mRNA		 CTD PMID:17505005 PMID:19502594 NCBI chr 3:161,713,777...161,764,844 JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 increases expression ISO Capsaicin results in increased expression of BCLAF1 mRNA CTD PMID:19502594 NCBI chr 1:16,904,572...16,937,106 JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA] CTD PMID:22264228 NCBI chr 6:130,275,631...130,284,968 JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP
ISO		 Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]
BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]		 CTD PMID:15363968 PMID:17347322 NCBI chr 6:130,237,055...130,267,205 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
affects expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of BDNF protein] CTD PMID:22150557 NCBI chr 3:116,619,633...116,670,212 JBrowse link
G Becn1 beclin 1 increases expression EXP Capsaicin results in increased expression of BECN1 mRNA CTD PMID:20349343 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
increases expression		 ISO Capsaicin results in increased cleavage of BID protein
Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]
Capsaicin results in increased expression of BID mRNA		 CTD PMID:19502594 PMID:22200406 NCBI chr 4:155,785,366...155,808,775 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Capsaicin results in increased expression of BIRC2 mRNA CTD PMID:19502594 NCBI chr 8:13,253,697...13,273,672 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions		 ISO Capsaicin results in decreased expression of BIRC5; Capsaicin results in decreased expression of BIRC5 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]		 CTD PMID:17505005 PMID:19002586 PMID:19939880 NCBI chr10:103,567,369...103,580,069 JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Capsaicin results in increased expression of BNIP2 mRNA CTD PMID:19502594 NCBI chr 8:70,640,436...70,661,782 JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BNIP3 mRNA
Capsaicin results in increased expression of BNIP3 mRNA		 CTD PMID:19502594 PMID:36044967 NCBI chr 1:203,137,778...203,154,962 JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BNIP3L mRNA
Capsaicin results in increased expression of BNIP3L mRNA		 CTD PMID:19502594 PMID:36044967 NCBI chr15:45,350,081...45,373,213 JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 decreases expression EXP Capsaicin results in decreased expression of CACNG3 mRNA CTD PMID:16278290 NCBI chr 1:177,201,361...177,297,019 JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression
increases secretion
decreases expression
multiple interactions
affects response to substance		 ISO
EXP		 Capsaicin results in increased expression of CALCA mRNA; Capsaicin results in increased expression of CALCA protein
Capsaicin results in increased secretion of CALCA protein
Capsaicin results in decreased expression of CALCA mRNA; Capsaicin results in decreased expression of CALCA protein
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; [Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Capsaicin results in decreased susceptibility to safranal] which results in decreased secretion of CALCA protein; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; butaprost promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Capsaicin promotes the reaction [Phenol results in decreased expression of CALCA protein]; Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; Dinoprostone promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Paclitaxel inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA mRNA]
CALCA protein affects the susceptibility to Capsaicin
[Capsaicin co-treated with Ethanol] results in increased expression of CALCA protein; CALCA protein affects the reaction [Capsaicin results in decreased susceptibility to Ethanol]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]		 CTD PMID:2462184 PMID:3412491 PMID:7473211 PMID:8971780 PMID:11738242 More... NCBI chr 1:178,312,636...178,317,588 JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression
decreases activity
multiple interactions
increases secretion		 ISO
EXP		 Capsaicin results in increased expression of CALCB mRNA
CALCB protein alternative form results in decreased activity of Capsaicin
Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]
capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCB mRNA]
Capsaicin results in increased secretion of CALCB protein		 CTD PMID:9932722 PMID:14764656 PMID:17434803 PMID:18584893 NCBI chr 1:168,965,383...168,970,259 JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Capsaicin results in increased phosphorylation of and results in increased expression of CAMK2A protein CTD PMID:12019337 NCBI chr18:56,648,779...56,711,505 JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CAMP protein
Glyoxal promotes the reaction [Capsaicin results in increased expression of CAMP protein]		 CTD PMID:29496360 NCBI chr 8:109,841,729...109,843,543 JBrowse link
G Casp2 caspase 2 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein CTD PMID:19939880 NCBI chr 4:72,116,265...72,134,023 JBrowse link
G Casp3 caspase 3 increases expression
affects cleavage
affects activity
increases activity
multiple interactions
increases cleavage
affects expression		 ISO
EXP		 Capsaicin results in increased expression of CASP3 protein
Capsaicin affects the cleavage of CASP3 protein
Capsaicin affects the activity of CASP3 protein
Capsaicin results in increased activity of CASP3 protein
Capsaicin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased activity of CASP3 protein]
Capsaicin results in increased cleavage of CASP3 protein
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein; Capsaicin promotes the reaction [resveratrol results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein; capsazepine inhibits the reaction [Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; resveratrol promotes the reaction [Capsaicin results in increased activity of CASP3 protein]
Capsaicin affects the expression of CASP3 protein		 CTD PMID:11275362 PMID:16125681 PMID:16477149 PMID:17295509 PMID:17306913 More... NCBI chr16:52,395,539...52,413,794 JBrowse link
G Casp4 caspase 4 increases activity
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in increased activity of CASP4 protein
Capsaicin results in increased cleavage of and results in increased activity of CASP4 protein
Capsaicin results in increased expression of CASP4 mRNA		 CTD PMID:19139269 PMID:19699254 PMID:20349343 PMID:20371669 NCBI chr 8:10,883,817...10,919,978 JBrowse link
G Casp6 caspase 6 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein CTD PMID:19939880 NCBI chr 2:221,140,287...221,152,727 JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity		 ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein
Capsaicin results in increased activity of CASP7 protein		 CTD PMID:19139269 PMID:19699254 PMID:19855437 PMID:19939880 NCBI chr 1:265,442,647...265,481,938 JBrowse link
G Casp8 caspase 8 increases activity
decreases expression
multiple interactions
increases expression		 ISO Capsaicin results in increased activity of CASP8 protein
Capsaicin results in decreased expression of CASP8 protein
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; Capsaicin promotes the reaction [resveratrol results in decreased expression of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of CASP8 protein]
Capsaicin results in increased expression of CASP8 mRNA		 CTD PMID:19502594 PMID:19846903 PMID:19939880 PMID:22200406 NCBI chr 9:67,747,109...67,806,699 JBrowse link
G Casp9 caspase 9 increases cleavage
increases activity
multiple interactions
increases expression
affects expression		 ISO
EXP		 Capsaicin results in increased cleavage of CASP9 protein
Capsaicin results in increased activity of CASP9 protein
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]
Capsaicin results in increased expression of CASP9 protein
Capsaicin affects the expression of CASP9 protein
Capsaicin results in increased expression of CASP9 mRNA		 CTD PMID:16125681 PMID:16477149 PMID:19502594 PMID:19699254 PMID:19855437 More...
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]
Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CAT]		 CTD PMID:14871840 PMID:18023135 PMID:18338764 PMID:21647434 NCBI chr 3:110,297,340...110,329,526 JBrowse link
G Cck cholecystokinin multiple interactions ISO
EXP		 [Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]
Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10683199 PMID:22508518 NCBI chr 8:121,153,499...121,160,194 JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP Capsaicin results in increased expression of CCL19 mRNA CTD PMID:20349343 NCBI chr 5:56,963,364...56,965,308 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
decreases secretion
increases expression		 EXP
ISO		 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CCL2 protein]
Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Capsaicin results in decreased expression of CCL2 mRNA; Capsaicin results in decreased expression of CCL2 protein
Capsaicin results in decreased secretion of CCL2 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of CCL2 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of CCL2 protein]
Capsaicin results in increased expression of CCL2 mRNA; Capsaicin results in increased expression of CCL2 protein		 CTD PMID:17719033 PMID:19798065 PMID:20349343 PMID:22150557 PMID:30244119 NCBI chr10:67,503,077...67,504,875 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CCL20 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]		 CTD PMID:22150557 NCBI chr 9:91,837,139...91,839,736 JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL22 protein] CTD PMID:22150557 NCBI chr19:10,263,589...10,270,359 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO
EXP		 Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]		 CTD PMID:21745629 PMID:22150557 NCBI chr10:68,948,889...68,950,439 JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Capsaicin results in decreased expression of CCNA2 protein CTD PMID:19939880 NCBI chr 2:121,355,363...121,361,762 JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Capsaicin results in decreased expression of CCNB1 protein CTD PMID:19939880 NCBI chr 2:33,646,252...33,655,225 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Capsaicin results in decreased expression of CCND1 protein CTD PMID:17505005 PMID:19855437 NCBI chr 1:209,518,288...209,527,986 JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Capsaicin results in increased expression of CCNL1 mRNA CTD PMID:20349343 NCBI chr 2:152,495,169...152,508,855 JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]		 CTD PMID:22150557 NCBI chr 8:114,176,291...114,182,033 JBrowse link
G Cd46 CD46 molecule increases expression EXP Capsaicin results in increased expression of CD46 mRNA CTD PMID:16278290 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd68 Cd68 molecule decreases expression ISO Capsaicin results in decreased expression of CD68 mRNA CTD PMID:19798065 NCBI chr10:54,880,562...54,882,441 JBrowse link
G Cd80 Cd80 molecule increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CD80 protein
[Naproxen co-treated with Sumatriptan] affects the reaction [Capsaicin results in increased expression of CD80 protein]; Naproxen affects the reaction [Capsaicin results in increased expression of CD80 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CD80 protein]		 CTD PMID:22150557 NCBI chr11:75,760,073...75,798,978 JBrowse link
G Cd8b CD8 subunit beta increases expression EXP Capsaicin results in increased expression of CD8B mRNA CTD PMID:16278290 NCBI chr 4:104,870,911...104,886,838 JBrowse link
G Cdc14a cell division cycle 14A increases expression EXP Capsaicin results in increased expression of CDC14A mRNA CTD PMID:20349343 NCBI chr 2:204,225,540...204,380,927 JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CDH1 protein
acadesine promotes the reaction [Capsaicin results in increased expression of CDH1 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased expression of CDH1 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of CDH1 protein]		 CTD PMID:36044967 NCBI chr19:51,402,178...51,471,572 JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression		 ISO acadesine promotes the reaction [Capsaicin results in decreased expression of CDH2 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein]; dorsomorphin inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein] CTD PMID:36044967 NCBI chr18:8,051,097...8,265,288 JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Capsaicin results in increased expression of CDK1 mRNA CTD PMID:20349343 NCBI chr20:19,265,252...19,280,456 JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Capsaicin results in decreased expression of CDK2 protein CTD PMID:20646592 NCBI chr 7:1,714,392...1,721,964 JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP Capsaicin results in decreased expression of CDK4 mRNA CTD PMID:16278290 NCBI chr 7:64,771,453...64,774,891 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression		 ISO Capsaicin results in increased expression of CDKN1A mRNA; Capsaicin results in increased expression of CDKN1A protein
Capsaicin results in decreased expression of CDKN1A protein		 CTD PMID:16540674 PMID:19502594 PMID:20646592 PMID:22226932 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
decreases expression		 ISO Capsaicin results in increased expression of CDKN1B
Capsaicin results in increased expression of CDKN1B protein
Capsaicin results in decreased expression of CDKN1B protein		 CTD PMID:19855437 PMID:20069556 PMID:22226932 NCBI chr 4:169,491,273...169,496,500 JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Capsaicin results in increased expression of CDKN2A mRNA CTD PMID:18533110 NCBI chr 5:109,100,763...109,114,448 JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of CEBPA protein
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA]		 CTD PMID:17295509 PMID:20359164 NCBI chr 1:87,759,631...87,762,303 JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases activity		 ISO [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]
Capsaicin results in increased activity of CEBPB protein
[Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]		 CTD PMID:20110283 PMID:21250977 NCBI chr 3:176,817,005...176,818,436 JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium; Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein; Egtazic Acid inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] CTD PMID:17303079 NCBI chr 1:212,227,124...212,230,656 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression
decreases expression		 ISO Capsaicin results in increased expression of CFLAR mRNA
Capsaicin results in decreased expression of CFLAR protein alternative form		 CTD PMID:19502594 PMID:19939880 NCBI chr 9:67,679,502...67,747,226 JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Capsaicin results in increased activity of CFTR protein; Capsaicin results in increased activity of CFTR protein mutant form CTD PMID:15155835 NCBI chr 4:47,422,084...47,694,646 JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Capsaicin results in increased expression of CHEK2 mRNA CTD PMID:19502594 NCBI chr12:51,448,838...51,481,159 JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions ISO Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA] CTD PMID:19825429 NCBI chr10:5,139,947...5,187,493 JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CILK1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]		 CTD PMID:22150557 NCBI chr 8:87,868,294...87,922,995 JBrowse link
G Cldn1 claudin 1 increases expression EXP Capsaicin results in increased expression of CLDN1 mRNA CTD PMID:16278290 NCBI chr11:87,926,376...87,941,533 JBrowse link
G Clec2d C-type lectin domain family 2, member D decreases expression EXP Capsaicin results in decreased expression of CLEC2D mRNA CTD PMID:16278290 NCBI chr 4:163,902,124...163,925,587 JBrowse link
G Clk1 CDC-like kinase 1 increases expression EXP Capsaicin results in increased expression of CLK1 mRNA CTD PMID:20349343 NCBI chr 9:67,441,962...67,453,180 JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases activity
affects response to substance		 ISO
EXP		 CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
Capsaicin results in increased activity of CNR1 protein
CNR1 protein affects the susceptibility to Capsaicin		 CTD PMID:11408034 PMID:18987195 NCBI chr 5:53,204,867...53,230,396 JBrowse link
G Cntf ciliary neurotrophic factor increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CNTF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTF protein]		 CTD PMID:22150557 NCBI chr 1:209,887,854...209,889,877 JBrowse link
G Cntfr ciliary neurotrophic factor receptor multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTFR protein] CTD PMID:22150557 NCBI chr 5:56,823,448...56,861,049 JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO Capsaicin results in increased expression of COL18A1 mRNA CTD PMID:21310942 NCBI chr20:11,474,104...11,582,593 JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Capsaicin results in increased expression of COL1A1 mRNA CTD PMID:20349343 NCBI chr10:80,380,458...80,397,461 JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Capsaicin results in increased expression of COL3A1 mRNA CTD PMID:20349343 NCBI chr 9:54,866,646...54,902,578 JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression EXP Capsaicin results in increased expression of COX4I1 protein CTD PMID:18079164 NCBI chr19:65,630,383...65,636,623 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression ISO Capsaicin results in increased expression of COX5A protein CTD PMID:18991268 NCBI chr 8:66,818,284...66,829,691 JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 increases expression EXP Capsaicin results in increased expression of COX6A1 mRNA CTD PMID:16278290 NCBI chr12:41,261,983...41,265,037 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA]
Capsaicin results in increased expression of CPT1A mRNA		 CTD PMID:20359164 PMID:21745629 NCBI chr 1:209,993,881...210,056,329 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; NPC 15437 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein] CTD PMID:15385614 PMID:15631885 PMID:16159392 NCBI chr 9:73,397,333...73,466,339 JBrowse link
G Csf2 colony stimulating factor 2 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CSF2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]		 CTD PMID:22150557 NCBI chr10:38,887,692...38,889,673 JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2A1 protein CTD PMID:20510015 NCBI chr 3:161,170,295...161,217,073 JBrowse link
G Csnk2b casein kinase 2 beta increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2B protein CTD PMID:20510015 NCBI chr20:3,704,833...3,709,999 JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CTNNB1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]		 CTD PMID:22150557 NCBI chr 8:129,517,576...129,544,661 JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 affects expression
multiple interactions		 EXP Capsaicin affects the expression of CX3CL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]		 CTD PMID:22150557 NCBI chr19:10,233,326...10,244,856 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CXCL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]		 CTD PMID:22150557 NCBI chr14:15,989,066...15,991,263 JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CXCL2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]		 CTD PMID:22150557 NCBI chr14:17,465,210...17,467,255 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of CXCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]		 CTD PMID:22150557 NCBI chr13:42,630,383...42,634,288 JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO
EXP		 CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]		 CTD PMID:18203709 PMID:20712533 NCBI chr  X:16,030,596...16,065,065 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression		 ISO [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin affects the expression of and affects the activity of CYP1A1 protein; Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
Capsaicin affects the expression of CYP1A1 mRNA		 CTD PMID:19449198 PMID:21250977 NCBI chr 8:66,991,940...66,998,014 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Capsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 NCBI chr 8:66,971,261...66,978,149 JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP Capsaicin results in decreased expression of CYP2A2 mRNA CTD PMID:16278290 NCBI chr 1:82,263,833...82,289,487 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Capsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 NCBI chr 1:247,879,058...247,916,804 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Capsaicin results in decreased activity of CYP2D6 protein CTD PMID:22375877 NCBI chr 7:115,762,662...115,771,832 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Capsaicin results in increased expression of CYP2E1 CTD PMID:22375877 NCBI chr 1:205,269,967...205,280,365 JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
decreases activity		 EXP
ISO		 Capsaicin results in decreased expression of CYP3A2 mRNA; Capsaicin results in decreased expression of CYP3A2 protein
Capsaicin results in decreased activity of CYP3A4 protein		 CTD PMID:20388821 PMID:24013073 NCBI chr12:14,321,771...14,343,886 JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Capsaicin results in decreased expression of CYP3A23-3A1 mRNA; Capsaicin results in decreased expression of CYP3A23-3A1 protein CTD PMID:24013073 NCBI chr12:14,369,950...14,398,803 JBrowse link
G Dap death-associated protein increases expression ISO Capsaicin results in increased expression of DAP mRNA CTD PMID:36044967 NCBI chr 2:82,199,206...82,251,771 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects localization		 EXP
ISO		 Capsaicin results in increased expression of DDIT3 protein
Capsaicin affects the localization of DDIT3 protein
Capsaicin analog results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3; Capsaicin results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3 protein		 CTD PMID:18533110 PMID:19139269 PMID:19285962 PMID:19331147 PMID:19699254 More... NCBI chr 7:65,001,695...65,006,517 JBrowse link
G Defb2 defensin beta 2 multiple interactions
increases expression		 EXP Glyoxal promotes the reaction [Capsaicin results in increased expression of DEFB2 protein] CTD PMID:29496360 NCBI chr16:70,231,870...70,245,817 JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Capsaicin results in increased expression of DEPP1 mRNA CTD PMID:36044967 NCBI chr 4:149,910,794...149,913,013 JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Capsaicin results in decreased expression of DFFA CTD PMID:16188123 NCBI chr 5:159,540,715...159,553,639 JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression EXP Capsaicin results in decreased expression of DPP3 mRNA CTD PMID:20349343 NCBI chr 1:202,204,683...202,228,501 JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein] CTD PMID:22171160 NCBI chr10:17,184,853...17,187,646 JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Capsaicin results in increased expression of E2F1 mRNA CTD PMID:19502594 NCBI chr 3:163,524,739...163,535,563 JBrowse link
G Edn1 endothelin 1 decreases activity
multiple interactions		 ISO EDN1 protein results in decreased activity of Capsaicin
EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; FR 139317 inhibits the reaction [EDN1 protein results in decreased activity of Capsaicin]		 CTD PMID:9932722 PMID:19429182 NCBI chr17:22,660,799...22,666,687 JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of EEF2 protein] CTD PMID:20359164 NCBI chr 7:9,183,836...9,196,255 JBrowse link
G Egf epidermal growth factor multiple interactions
decreases expression
decreases activity		 ISO
EXP		 Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP14]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein]
Capsaicin results in decreased expression of EGF protein
Capsaicin results in decreased activity of EGF protein		 CTD PMID:9324159 PMID:14521749 PMID:21462327 NCBI chr 2:220,893,660...220,976,331 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
increases phosphorylation		 ISO
EXP		 AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; RTKI cpd inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]
Capsaicin results in decreased expression of EGFR protein
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]		 CTD PMID:14521749 PMID:19855437 PMID:20619260 PMID:20660715 PMID:21462327 NCBI chr14:95,378,626...95,551,358 JBrowse link
G Egr1 early growth response 1 increases expression EXP Capsaicin results in increased expression of EGR1 mRNA CTD PMID:20349343 NCBI chr18:26,737,078...26,740,877 JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO
EXP		 Capsaicin results in increased phosphorylation of EIF2A protein CTD PMID:18533110 PMID:19285962 NCBI chr 2:142,761,303...142,794,767 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Capsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 NCBI chr 6:103,405,880...103,430,549 JBrowse link
G Eln elastin increases expression EXP Capsaicin results in increased expression of ELN mRNA CTD PMID:16278290 NCBI chr12:27,604,983...27,648,413 JBrowse link
G Eno2 enolase 2 multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of ENO2 protein] CTD PMID:19449198 NCBI chr 4:159,258,371...159,267,220 JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 increases response to substance ISO ENOX2 results in increased susceptibility to Capsaicin CTD PMID:15706060 NCBI chr  X:128,270,941...128,593,074 JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr 7:88,092,140...88,214,758 JBrowse link
G Epor erythropoietin receptor increases expression ISO Capsaicin results in increased expression of EPOR mRNA; Capsaicin results in increased expression of EPOR protein CTD PMID:17603282 NCBI chr 8:28,765,738...28,770,371 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects expression
decreases expression		 ISO Capsaicin affects the expression of ERBB2 mRNA
Capsaicin results in decreased expression of ERBB2 protein		 CTD PMID:19502594 PMID:19855437 NCBI chr10:83,907,491...83,931,365 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Capsaicin results in increased expression of ERN1 protein CTD PMID:19139269 PMID:19699254 NCBI chr10:91,826,663...91,920,976 JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein] CTD PMID:22150557 NCBI chr 5:166,606,841...166,620,124 JBrowse link
G Etfa electron transfer flavoprotein subunit alpha multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of ETFA protein] CTD PMID:20359164 NCBI chr 8:55,835,115...55,891,890 JBrowse link
G Exosc8 exosome component 8 decreases expression EXP Capsaicin results in decreased expression of EXOSC8 mRNA CTD PMID:16278290 NCBI chr 2:138,930,405...138,937,009 JBrowse link
G F2 coagulation factor II, thrombin affects expression EXP Capsaicin affects the expression of F2 protein CTD PMID:8285224 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 2:28,507,003...28,519,954 JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of FABP4 mRNA
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of FABP4 mRNA]; Capsaicin inhibits the reaction [Dietary Fats results in increased expression of FABP4 protein]		 CTD PMID:18533110 PMID:20359164 NCBI chr 2:93,488,251...93,492,961 JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Capsaicin results in decreased expression of FABP5 mRNA CTD PMID:18533110 NCBI chr 2:91,765,056...91,768,716 JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions		 EXP Capsaicin results in increased expression of FADD protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FADD protein]		 CTD PMID:22150557 NCBI chr 1:209,169,245...209,175,423 JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression EXP Capsaicin results in decreased expression of FAM162A mRNA CTD PMID:16278290 NCBI chr11:78,186,260...78,215,186 JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
affects expression		 ISO
EXP		 Capsaicin results in increased expression of FAS mRNA; Capsaicin results in increased expression of FAS protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FAS protein]
Capsaicin promotes the reaction [resveratrol results in increased expression of FAS protein]
Capsaicin affects the expression of FAS mRNA		 CTD PMID:19502594 PMID:19846903 PMID:21310942 PMID:22150557 NCBI chr 1:241,212,155...241,245,774 JBrowse link
G Faslg Fas ligand multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FASLG protein] CTD PMID:22150557 NCBI chr13:76,680,885...76,706,042 JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression ISO Capsaicin results in increased expression of FBXL2 mRNA CTD PMID:36044967 NCBI chr 8:113,916,660...113,965,137 JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Capsaicin results in increased expression of FDFT1 mRNA CTD PMID:33512557 NCBI chr15:41,588,114...41,616,168 JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP Capsaicin results in increased expression of FDPS mRNA CTD PMID:16278290 NCBI chr 2:176,795,192...176,804,816 JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Capsaicin results in decreased expression of FGF2 protein CTD PMID:14521749 NCBI chr 2:122,164,454...122,218,796 JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 multiple interactions
affects expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein] CTD PMID:22150557 NCBI chr14:71,316,171...71,319,965 JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression EXP Capsaicin results in decreased expression of FGFR1 protein CTD PMID:14521749 NCBI chr16:73,194,631...73,249,855 JBrowse link
G Fgl1 fibrinogen-like 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FGL1 protein] CTD PMID:22150557 NCBI chr16:51,120,652...51,150,907 JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression EXP Capsaicin results in decreased expression of FKBP4 mRNA CTD PMID:20349343 NCBI chr 4:163,389,464...163,397,918 JBrowse link
G Flcn folliculin increases expression ISO Capsaicin results in increased expression of FLCN mRNA CTD PMID:36044967 NCBI chr10:45,088,164...45,107,581 JBrowse link
G Fmod fibromodulin increases expression EXP Capsaicin results in increased expression of FMOD mRNA CTD PMID:20349343 NCBI chr13:45,493,517...45,504,134 JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha increases expression EXP Capsaicin results in increased expression of FNTA mRNA CTD PMID:16278290 NCBI chr16:66,065,131...66,083,460 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of FOS mRNA
Capsaicin results in increased expression of FOS protein
Capsaicin results in increased expression of FOS; Capsaicin results in increased expression of FOS mRNA; Capsaicin results in increased expression of FOS protein
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Capsaicin results in increased expression of FOS]; 2-amino-4-phosphonobutyric acid inhibits the reaction [Capsaicin results in increased expression of FOS]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased expression of FOS]; Capsaicin inhibits the reaction [8-sulfocholecystokinin octapeptide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein]; Melatonin inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]
Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]; Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]; GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]; HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; LY 344864 inhibits the reaction [Capsaicin results in increased expression of FOS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FOS protein]		 CTD PMID:1922926 PMID:9372230 PMID:9580328 PMID:10401552 PMID:10749792 More... NCBI chr 6:110,852,188...110,855,054 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased expression of FOSL1 protein] CTD PMID:20054487 NCBI chr 1:212,183,885...212,192,391 JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Capsaicin results in decreased expression of FOXA1 mRNA CTD PMID:18533110 NCBI chr 6:75,099,907...75,136,534 JBrowse link
G Foxe3 forkhead box E3 increases expression EXP Capsaicin results in increased expression of FOXE3 mRNA CTD PMID:16278290 NCBI chr 5:128,444,912...128,446,494 JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein] CTD PMID:22150557 NCBI chr11:62,895,391...62,948,581 JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 increases expression EXP Capsaicin results in increased expression of FXYD6 mRNA CTD PMID:16278290 NCBI chr 8:45,679,054...45,705,958 JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 increases expression EXP Capsaicin results in increased expression of GABRR3 mRNA CTD PMID:16278290 NCBI chr11:40,902,812...40,955,263 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Capsaicin results in increased expression of GADD45A mRNA CTD PMID:19502594 NCBI chr 4:97,484,497...97,486,799 JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
increases expression
decreases response to substance		 EXP
ISO		 GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
Capsaicin results in increased expression of GAL mRNA
GAL protein results in decreased susceptibility to Capsaicin		 CTD PMID:8971780 PMID:17999197 PMID:18553211 PMID:19112407 NCBI chr 1:210,079,709...210,084,572 JBrowse link
G Galr2 galanin receptor 2 increases expression EXP Capsaicin results in increased expression of GALR2 mRNA CTD PMID:18553211 NCBI chr10:101,513,689...101,517,176 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of GAPDH protein
Capsaicin inhibits the reaction [Dietary Fats results in increased expression of GAPDH protein]		 CTD PMID:18991268 PMID:20359164 NCBI chr 4:157,962,312...157,967,158 JBrowse link
G Gast gastrin increases secretion
decreases secretion		 EXP Capsaicin results in increased secretion of GAST protein
Capsaicin results in decreased secretion of GAST protein		 CTD PMID:8093880 PMID:19208342 PMID:19296048 NCBI chr10:85,264,832...85,269,393 JBrowse link
G Gata1 GATA binding protein 1 increases expression ISO Capsaicin results in increased expression of GATA1 mRNA CTD PMID:17603282 NCBI chr  X:14,529,706...14,537,530 JBrowse link
G Gcg glucagon multiple interactions ISO Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] CTD PMID:1378463 NCBI chr 3:67,522,489...67,531,533 JBrowse link
G Gch1 GTP cyclohydrolase 1 affects response to substance ISO GCH1 gene SNP affects the susceptibility to Capsaicin CTD PMID:19081190 NCBI chr15:20,404,267...20,437,727 JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases phosphorylation
increases expression		 ISO [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]
Capsaicin results in increased phosphorylation of GDF15 protein		 CTD PMID:20110283 NCBI chr16:18,838,436...18,842,022 JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of GFAP mRNA
Capsaicin results in increased expression of GFAP protein
7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; [7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; pimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]		 CTD PMID:18405923 PMID:19285962 PMID:20826152 NCBI chr10:88,352,987...88,361,661 JBrowse link
G Gfra1 GDNF family receptor alpha 1 affects expression
multiple interactions		 EXP Capsaicin affects the expression of GFRA1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]		 CTD PMID:22150557 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression
multiple interactions		 EXP Capsaicin affects the expression of GFRA2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]		 CTD PMID:22150557 NCBI chr15:52,351,499...52,443,369 JBrowse link
G Gh1 growth hormone 1 decreases secretion
increases expression
multiple interactions		 EXP Capsaicin results in decreased secretion of GH protein
Capsaicin results in increased expression of GH1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GH1 protein]		 CTD PMID:12360474 PMID:22150557 NCBI chr10:91,727,883...91,729,860 JBrowse link
G Ghr growth hormone receptor increases expression
multiple interactions		 EXP Capsaicin results in increased expression of GHR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GHR protein]		 CTD PMID:22150557 NCBI chr 2:52,541,452...52,804,960 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions
decreases activity		 ISO
EXP		 GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin results in decreased activity of GHRL protein
Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]		 CTD PMID:12360474 PMID:15177919 PMID:18202139 NCBI chr 4:146,865,712...146,869,621 JBrowse link
G Gjb6 gap junction protein, beta 6 increases expression EXP Capsaicin results in increased expression of GJB6 mRNA CTD PMID:20349343 NCBI chr15:31,284,561...31,294,552 JBrowse link
G Glp1r glucagon-like peptide 1 receptor decreases expression EXP Capsaicin results in decreased expression of GLP1R mRNA CTD PMID:22031786 NCBI chr20:8,972,004...9,010,241 JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression ISO Capsaicin results in increased expression of GLUD1 protein CTD PMID:18991268 NCBI chr16:9,640,312...9,673,961 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GOT1 protein] CTD PMID:16956363 NCBI chr 1:252,306,541...252,337,622 JBrowse link
G Gpr132 G protein-coupled receptor 132 decreases expression ISO Capsaicin results in decreased expression of GPR132 mRNA CTD PMID:19602228 NCBI chr 6:137,745,142...137,763,037 JBrowse link
G Gpr176 G protein-coupled receptor 176 decreases expression EXP Capsaicin results in decreased expression of GPR176 mRNA CTD PMID:16278290 NCBI chr 3:125,690,750...125,791,172 JBrowse link
G Gpr4 G protein-coupled receptor 4 decreases expression ISO Capsaicin results in decreased expression of GPR4 mRNA CTD PMID:19602228 NCBI chr 1:78,865,376...78,877,126 JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GPT protein] CTD PMID:16956363 NCBI chr 7:110,295,599...110,300,134 JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX1 mRNA] CTD PMID:18926900 NCBI chr 8:117,905,462...117,906,588 JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX4 mRNA] CTD PMID:18926900 NCBI chr 7:10,300,833...10,303,629 JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases phosphorylation
multiple interactions		 EXP Capsaicin results in increased phosphorylation of GRIA1 protein
KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein]		 CTD PMID:12019337 NCBI chr10:41,710,540...42,030,105 JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases phosphorylation
increases expression		 EXP N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN1 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of GRIN1 protein modified form] CTD PMID:17317010 PMID:20054487 NCBI chr 3:28,501,836...28,528,754 JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases phosphorylation
multiple interactions		 EXP Capsaicin results in increased phosphorylation of GRIN2B protein
capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]; Excitatory Amino Acid Antagonists inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]		 CTD PMID:18577691 NCBI chr 4:170,297,811...170,775,420 JBrowse link
G Grk6 G protein-coupled receptor kinase 6 multiple interactions
decreases response to substance		 ISO GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]
GRK6 results in decreased susceptibility to Capsaicin		 CTD PMID:18687398 NCBI chr17:9,182,160...9,198,380 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA] CTD PMID:20110283 NCBI chr11:76,004,502...76,154,665 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSR] CTD PMID:18023135 PMID:18338764 NCBI chr16:65,185,574...65,228,742 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA] CTD PMID:15313406 NCBI chr 1:210,767,237...210,770,242 JBrowse link
G Gypa glycophorin A increases expression ISO Capsaicin results in increased expression of GYPA mRNA CTD PMID:17603282 NCBI chr19:27,450,304...27,465,940 JBrowse link
G Gzma granzyme A multiple interactions
increases expression		 ISO Capsaicin results in increased expression of and results in increased secretion of GZMA protein
Capsaicin results in increased expression of GZMA mRNA		 CTD PMID:21310942 NCBI chr 2:44,740,569...44,752,502 JBrowse link
G H2ax H2A.X variant histone increases localization ISO Capsaicin results in increased localization of H2AX protein CTD PMID:22226932 NCBI chr 8:53,568,718...53,570,072 JBrowse link
G H2bc1 H2B clustered histone 1 decreases expression EXP Capsaicin results in decreased expression of H2BC1 mRNA CTD PMID:16278290 NCBI chr17:41,172,041...41,172,510 JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of H6PD protein] CTD PMID:18338764 NCBI chr 5:160,434,499...160,470,203 JBrowse link
G Hbb hemoglobin subunit beta increases expression ISO Capsaicin results in increased expression of HBB-B1 mRNA CTD PMID:17603282 NCBI chr 1:167,662,310...167,663,721 JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA CTD PMID:20660715 NCBI chr18:28,380,337...28,390,220 JBrowse link
G Hbg1 hemoglobin subunit gamma 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of HBG1 protein] CTD PMID:20359164 NCBI chr 1:158,271,871...158,273,426 JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of HCRT protein] CTD PMID:22150557 NCBI chr10:86,190,289...86,191,524 JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP Capsaicin results in increased expression of HDAC2 mRNA CTD PMID:16278290 NCBI chr20:42,101,815...42,126,486 JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 increases expression EXP Capsaicin results in increased expression of HEY2 mRNA CTD PMID:16278290 NCBI chr 1:26,822,131...26,832,218 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Capsaicin results in increased expression of HIF1A mRNA CTD PMID:12242509 NCBI chr 6:98,357,788...98,405,068 JBrowse link
G Hip1r huntingtin interacting protein 1 related decreases expression EXP Capsaicin results in decreased expression of HIP1R mRNA CTD PMID:20349343 NCBI chr12:38,251,085...38,279,756 JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP Capsaicin results in increased expression of HMGB2 mRNA CTD PMID:16278290 NCBI chr16:37,721,374...37,723,950 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of HMOX1 mRNA; Capsaicin results in increased expression of HMOX1 protein
Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]
Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of HMOX1 mRNA]; Capsaicin promotes the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein]		 CTD PMID:11738242 PMID:17979524 PMID:18617559 PMID:36044967 NCBI chr19:13,452,365...13,479,823 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP Capsaicin results in increased expression of HNRNPA1 mRNA CTD PMID:20349343 NCBI chr 7:136,253,633...136,260,085 JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression EXP Capsaicin results in increased expression of HPCAL1 mRNA CTD PMID:16278290 NCBI chr 6:40,478,206...40,584,721 JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Capsaicin results in increased expression of HRAS mRNA CTD PMID:9461043 NCBI chr 1:205,712,625...205,729,406 JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP Capsaicin results in increased expression of HSF1 mRNA CTD PMID:24746025 NCBI chr 7:110,076,710...110,103,665 JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of HSP90B1 protein
Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP90B1 protein]		 CTD PMID:18991268 PMID:20359164 NCBI chr 7:22,997,962...23,012,293 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
increases localization		 ISO Capsaicin results in increased expression of HSPA5; Capsaicin results in increased expression of HSPA5 protein
Capsaicin results in increased localization of HSPA5 protein		 CTD PMID:19139269 PMID:19331147 PMID:19699254 PMID:21859781 NCBI chr 3:38,453,016...38,457,475 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP27 protein] CTD PMID:20359164 NCBI chr12:26,430,640...26,432,301 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B multiple interactions ISO HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 8:91,395,405...91,414,815 JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D multiple interactions ISO HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 5:153,939,735...153,960,012 JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F multiple interactions ISO HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr11:2,642,751...2,644,150 JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases activity ISO Capsaicin results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:58,138,514...58,150,960 JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B decreases expression EXP Capsaicin results in decreased expression of HTR3B mRNA CTD PMID:16278290 NCBI chr 8:49,279,291...49,308,444 JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of ICAM1] CTD PMID:20600813 NCBI chr 8:27,829,688...27,841,618 JBrowse link
G Ide insulin degrading enzyme multiple interactions
affects expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IDE protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IDE protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IDE protein] CTD PMID:22150557 NCBI chr 1:244,415,495...244,516,925 JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of IFNG
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA]; Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]
[Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of IFNG mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]		 CTD PMID:14530214 PMID:17306834 PMID:19825429 PMID:22150557 PMID:29496360 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression		 ISO
EXP		 CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; Isoflavones promotes the reaction [Capsaicin results in increased expression of IGF1 protein]
Capsaicin results in increased expression of IGF1 mRNA; Capsaicin results in increased expression of IGF1 protein
[Capsaicin co-treated with Isoflavones] results in increased expression of IGF1 protein; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]
capsazepine inhibits the reaction [Capsaicin results in increased expression of IGF1 protein]		 CTD PMID:17307377 PMID:17569567 PMID:17693108 PMID:19502719 PMID:21310942 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of IGF1R mRNA
TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]		 CTD PMID:21310942 NCBI chr 1:130,959,787...131,248,664 JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP Capsaicin results in increased expression of IGF2 mRNA CTD PMID:20349343 NCBI chr 1:197,814,409...197,831,802 JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]
Capsaicin results in increased expression of IL10 mRNA; Capsaicin results in increased expression of IL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL10 protein]		 CTD PMID:15502055 PMID:18460982 PMID:19878665 PMID:22150557 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 decreases expression EXP Capsaicin results in decreased expression of IL11RA1 mRNA CTD PMID:16278290 NCBI chr 5:61,727,650...61,737,265 JBrowse link
G Il12b interleukin 12B decreases expression ISO Capsaicin results in decreased expression of IL12B mRNA CTD PMID:18533110 NCBI chr10:29,390,300...29,405,194 JBrowse link
G Il13 interleukin 13 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL13 protein] CTD PMID:22150557 NCBI chr10:38,290,926...38,293,483 JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] CTD PMID:22150557 NCBI chr 3:136,979,804...136,990,236 JBrowse link
G Il1b interleukin 1 beta decreases secretion
increases response to substance
multiple interactions
increases expression
affects expression		 ISO
EXP		 Capsaicin results in decreased secretion of IL1B protein
IL1B gene SNP results in increased susceptibility to Capsaicin
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of IL1B mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of IL1B protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL1B protein]
Capsaicin results in increased expression of IL1B mRNA; Capsaicin results in increased expression of IL1B protein
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]
Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]		 CTD PMID:12034025 PMID:15265675 PMID:18769453 PMID:19878665 PMID:22150557 More... NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP IL1RN protein inhibits the reaction [Nicotine results in increased activity of Capsaicin] CTD PMID:27180639 NCBI chr 3:27,509,836...27,525,738 JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of IL2
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL2 protein]		 CTD PMID:17306834 PMID:22150557 NCBI chr 2:121,932,968...121,937,672 JBrowse link
G Il3 interleukin 3 multiple interactions
affects expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL3 protein] CTD PMID:22150557 NCBI chr10:38,906,460...38,908,810 JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of IL4
Capsaicin results in increased expression of IL4 mRNA; Capsaicin results in increased expression of IL4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL4 protein]		 CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr10:38,272,003...38,277,549 JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of IL5
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL5 protein]
Capsaicin results in increased expression of IL5 mRNA; Capsaicin results in increased expression of IL5 protein		 CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr10:38,375,132...38,378,003 JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases secretion
decreases expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; RTKI cpd affects the reaction [Capsaicin results in increased secretion of IL6 protein]; Ruthenium Red inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in increased expression of IL6 mRNA; Capsaicin results in increased expression of IL6 protein
Capsaicin results in decreased secretion of IL6 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in decreased expression of IL6 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of IL6 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of IL6 protein]
Capsaicin results in decreased expression of IL6 mRNA; Capsaicin results in decreased expression of IL6 protein		 CTD PMID:15265675 PMID:15502055 PMID:16173059 PMID:17306835 PMID:17505005 More... NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression EXP Capsaicin results in decreased expression of IL6ST protein CTD PMID:19285962 NCBI chr 2:45,798,872...45,839,501 JBrowse link
G Il7 interleukin 7 decreases expression EXP Capsaicin results in decreased expression of IL7 mRNA CTD PMID:16278290 NCBI chr 2:96,142,523...96,186,282 JBrowse link
G Inhba inhibin subunit beta A increases expression
multiple interactions		 EXP Capsaicin results in increased expression of INHBA protein
Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of INHBA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of INHBA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of INHBA protein]		 CTD PMID:22150557 PMID:36925032 NCBI chr17:53,787,159...53,810,942 JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression
increases expression
affects response to substance		 EXP
ISO		 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of INS1 protein]; Capsaicin promotes the reaction [Glucose results in increased secretion of INS1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of INS1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of INS1 protein]
Capsaicin results in decreased expression of INS1 protein
Capsaicin affects the susceptibility to INS1 protein		 CTD PMID:16322403 PMID:17241282 PMID:19798065 PMID:22150557 NCBI chr 1:261,186,119...261,186,686 JBrowse link
G Ins2 insulin 2 multiple interactions EXP [INS protein co-treated with Capsaicin] promotes the reaction [Capsaicin results in increased uptake of cobaltous chloride] CTD PMID:14622148 NCBI chr 1:207,272,738...207,421,998 JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Capsaicin results in increased expression of IRS1 mRNA CTD PMID:19798065 NCBI chr 9:91,001,137...91,053,959 JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP Capsaicin results in increased expression of ITGA5 mRNA CTD PMID:16278290 NCBI chr 7:136,358,097...136,381,305 JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO Capsaicin results in decreased phosphorylation of and results in decreased activity of JAK1 protein CTD PMID:17505005 NCBI chr 5:120,895,606...121,004,207 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of JUN mRNA
Capsaicin results in increased expression of JUN mRNA
[Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]		 CTD PMID:1922926 PMID:9580328 PMID:17292493 PMID:19502594 PMID:21462327 NCBI chr 5:115,009,900...115,012,993 JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression EXP Capsaicin results in increased expression of JUND mRNA CTD PMID:16278290 NCBI chr16:18,734,121...18,735,799 JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 increases expression EXP Capsaicin results in increased expression of KCNQ4 mRNA CTD PMID:16278290 NCBI chr 5:134,275,145...134,326,992 JBrowse link
G Kif11 kinesin family member 11 increases expression EXP Capsaicin results in increased expression of KIF11 mRNA CTD PMID:16278290 NCBI chr 1:244,494,916...244,589,250 JBrowse link
G Klf1 KLF transcription factor 1 increases expression ISO Capsaicin results in increased expression of KLF1 mRNA CTD PMID:17603282 NCBI chr19:23,250,627...23,253,802 JBrowse link
G Klf4 KLF transcription factor 4 increases expression EXP Capsaicin results in increased expression of KLF4 mRNA CTD PMID:20349343 NCBI chr 5:75,074,107...75,079,182 JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein] CTD PMID:16540674 NCBI chr 1:94,402,993...94,407,052 JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression EXP Capsaicin results in increased expression of KLK6 mRNA CTD PMID:20349343 NCBI chr 1:94,278,863...94,286,136 JBrowse link
G Kng1 kininogen 1 increases response to substance
multiple interactions
affects activity		 EXP
ISO		 KNG1 protein results in increased susceptibility to Capsaicin
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]
Capsaicin affects the activity of KNG1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [KNG1 protein results in increased susceptibility to Capsaicin]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]; Capsaicin promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 73343 promotes the reaction [KNG1 protein results in increased susceptibility to Capsaicin]
BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]		 CTD PMID:7807204 PMID:10490893 PMID:15363968 PMID:15750287 PMID:16696851 More... NCBI chr11:77,812,757...77,835,555 JBrowse link
G Lep leptin decreases expression
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of LEP protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of LEP mRNA]; Naproxen inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of LEP protein]
Capsaicin results in increased expression of LEP mRNA; Capsaicin results in increased expression of LEP protein		 CTD PMID:16278290 PMID:17295509 PMID:19798065 PMID:20359164 PMID:22150557 NCBI chr 4:58,626,529...58,640,663 JBrowse link
G Lgals1 galectin 1 increases expression ISO Capsaicin results in increased expression of LGALS1 protein CTD PMID:18991268 NCBI chr 7:112,365,695...112,368,801 JBrowse link
G LOC120095693 small ubiquitin-related modifier 2-like increases expression ISO Capsaicin results in increased expression of SUMO4 protein CTD PMID:18991268 NCBI chr11:79,163,457...79,164,088 JBrowse link
G Lrp1 LDL receptor related protein 1 multiple interactions
decreases response to substance
decreases expression		 ISO 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; [Capsaicin results in decreased expression of LRP1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in decreased expression of LRP1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; Cyclosporine inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; KT 5720 inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]
LRP1 results in decreased susceptibility to Capsaicin		 CTD PMID:21908651 NCBI chr 7:65,265,639...65,346,196 JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 decreases expression EXP Capsaicin results in decreased expression of LTB4R2 mRNA CTD PMID:16278290 NCBI chr15:29,258,712...29,260,531 JBrowse link
G Ltf lactotransferrin increases expression ISO Capsaicin results in increased expression of LTF protein CTD PMID:9537786 NCBI chr 8:110,999,948...111,022,795 JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
affects localization		 ISO acadesine promotes the reaction [Capsaicin affects the localization of MAP1LC3A protein]; dorsomorphin inhibits the reaction [Capsaicin affects the localization of MAP1LC3A protein] CTD PMID:36044967 NCBI chr 3:164,243,204...164,244,850 JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO Capsaicin results in increased expression of MAP2 mRNA CTD PMID:18405923 NCBI chr 9:75,173,038...75,431,606 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO Capsaicin results in increased expression of MAP2K1 mRNA CTD PMID:19502594 NCBI chr 8:73,578,747...73,650,184 JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions ISO 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein] CTD PMID:22171160 NCBI chr 5:51,149,524...51,212,012 JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases activity
increases phosphorylation
multiple interactions
increases expression
increases localization
increases activity		 ISO
EXP		 Capsaicin results in decreased activity of MAPK1 protein
Capsaicin results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]
Capsaicin results in increased expression of MAPK1 protein modified form
Capsaicin results in increased localization of MAPK1 protein modified form		 CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein] CTD PMID:21745629 NCBI chr20:6,751,288...6,812,294 JBrowse link
G Mapk15 mitogen-activated protein kinase 15 increases expression ISO Capsaicin results in increased expression of MAPK15 mRNA CTD PMID:36044967 NCBI chr 7:109,575,619...109,595,339 JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases activity
increases phosphorylation
multiple interactions
increases expression
increases localization
increases activity		 ISO
EXP		 Capsaicin results in decreased activity of MAPK3 protein
Capsaicin results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Ro 31-8425 promotes the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK3 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK3 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]
Capsaicin results in increased expression of MAPK3 protein modified form
Capsaicin results in increased localization of MAPK3 protein modified form		 CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr 1:190,797,189...190,803,411 JBrowse link
G Mapk7 mitogen-activated protein kinase 7 increases phosphorylation EXP Capsaicin results in increased phosphorylation of MAPK7 protein CTD PMID:17237256 NCBI chr10:46,669,721...46,675,768 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity
increases phosphorylation		 ISO 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; 7-oxozeanol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; [Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]
Capsaicin results in increased phosphorylation of MAPK8 protein		 CTD PMID:9580328 PMID:12478662 PMID:17292493 PMID:20619260 PMID:21462327 More... NCBI chr16:8,645,171...8,728,225 JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased activity of MAPK9 protein
Capsaicin results in increased phosphorylation of MAPK9 protein
Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]		 CTD PMID:9580328 PMID:20619260 PMID:21462327 PMID:21745629 NCBI chr10:34,670,750...34,711,972 JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Capsaicin results in increased expression of MAPT mRNA CTD PMID:36044967 NCBI chr10:89,638,618...89,736,108 JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP Capsaicin results in increased expression of MARCKS mRNA CTD PMID:20349343 NCBI chr20:42,240,185...42,245,882 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Capsaicin results in increased expression of MCL1 mRNA CTD PMID:19502594 PMID:36044967 NCBI chr 2:185,884,840...185,912,532 JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MDH1 protein] CTD PMID:20359164 NCBI chr14:95,630,625...95,645,920 JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
decreases expression
multiple interactions		 ISO Capsaicin results in increased expression of MDM2 mRNA
Capsaicin results in decreased expression of MDM2 protein
Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]		 CTD PMID:19502594 PMID:19846903 NCBI chr 7:55,176,558...55,201,757 JBrowse link
G Mif macrophage migration inhibitory factor increases expression
multiple interactions		 EXP Capsaicin results in increased expression of MIF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MIF protein]		 CTD PMID:22150557 NCBI chr20:12,790,919...12,791,784 JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Capsaicin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29155087 NCBI chr 1:199,926,150...199,952,847 JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein]
Capsaicin results in increased expression of MMP1 mRNA; Capsaicin results in increased expression of MMP1 protein		 CTD PMID:17508023 PMID:21310942 NCBI chr 8:12,943,453...12,963,966 JBrowse link
G Mmp12 matrix metallopeptidase 12 decreases expression ISO Capsaicin results in decreased expression of MMP12 mRNA; Capsaicin results in decreased expression of MMP12 protein CTD PMID:18441096 NCBI chr 8:4,581,785...4,591,687 JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression
multiple interactions
increases expression		 EXP Capsaicin results in decreased expression of MMP13 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]		 CTD PMID:16278290 PMID:22150557 NCBI chr 8:4,497,960...4,508,239 JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased expression of MMP14] CTD PMID:21462327 NCBI chr15:27,887,795...27,897,020 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO
EXP		 Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]
Capsaicin results in increased expression of MMP2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]		 CTD PMID:21462327 PMID:22150557 NCBI chr19:30,327,643...30,355,856 JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 ISO 4-aminobenzamide inhibits the reaction [Capsaicin results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin results in increased expression of and results in increased activity of MMP9 protein; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]
Capsaicin results in increased expression of MMP9 mRNA		 CTD PMID:21310942 PMID:21462327 PMID:22230393 NCBI chr 3:174,103,474...174,111,434 JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein increases expression EXP Capsaicin results in increased expression of MOBP mRNA CTD PMID:20349343 NCBI chr 8:119,869,504...119,899,605 JBrowse link
G Mog myelin oligodendrocyte glycoprotein increases expression EXP Capsaicin results in increased expression of MOG mRNA CTD PMID:20349343 NCBI chr20:1,514,110...1,528,716 JBrowse link
G Mpo myeloperoxidase affects activity
decreases expression
multiple interactions		 EXP Capsaicin affects the activity of MPO protein
Capsaicin results in decreased expression of MPO protein
Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Iodoacetamide results in increased activity of MPO protein]; Capsaicin promotes the reaction [Ethanol results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein]		 CTD PMID:10671773 PMID:12024109 PMID:12893632 PMID:15046732 PMID:15573930 NCBI chr10:73,092,124...73,102,057 JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 decreases expression EXP Capsaicin results in decreased expression of MRPL3 mRNA CTD PMID:16278290 NCBI chr 8:105,670,184...105,693,544 JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Capsaicin results in increased expression of MSMO1 mRNA CTD PMID:18533110 NCBI chr16:24,980,680...24,997,927 JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases response to substance
multiple interactions		 ISO ND1 gene mutant form results in increased susceptibility to Capsaicin
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein		 CTD PMID:29991444 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein]; acadesine promotes the reaction [Capsaicin results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Capsaicin results in decreased phosphorylation of MTOR protein]; Wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein] CTD PMID:19139269 PMID:22226932 PMID:36044967 NCBI chr 5:164,167,985...164,277,438 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases secretion
multiple interactions		 ISO Capsaicin results in increased secretion of MUC5AC protein
Capsaicin promotes the reaction [Citric Acid results in increased secretion of MUC5AC protein]		 CTD PMID:22566028 NCBI chr 1:206,293,717...206,326,006 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming increases secretion ISO Capsaicin results in increased secretion of MUC5B protein CTD PMID:21981454 NCBI chr 1:196,916,861...196,948,830 JBrowse link
G Musk muscle associated receptor tyrosine kinase multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MUSK protein] CTD PMID:22150557 NCBI chr 5:77,853,560...77,967,653 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Capsaicin results in increased expression of MYC mRNA CTD PMID:9461043 PMID:19502594 NCBI chr 7:95,483,105...95,488,031 JBrowse link
G Myl1 myosin, light chain 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MYL1 protein] CTD PMID:20359164 NCBI chr 9:68,437,514...68,458,256 JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Capsaicin results in decreased expression of MYL4 mRNA CTD PMID:33512557 NCBI chr10:89,949,733...89,985,308 JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 increases expression EXP Capsaicin results in increased expression of NCR1 mRNA CTD PMID:16278290 NCBI chr 1:78,657,409...78,665,255 JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 decreases expression EXP Capsaicin results in decreased expression of NDUFB4 mRNA CTD PMID:16278290 NCBI chr11:76,569,178...76,575,879 JBrowse link
G Nectin1 nectin cell adhesion molecule 1 increases expression EXP Capsaicin results in increased expression of NECTIN1 mRNA CTD PMID:16278290 NCBI chr 8:44,101,776...44,164,863 JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO Capsaicin results in increased expression of NEK2 mRNA CTD PMID:33512557 NCBI chr13:105,936,809...105,950,054 JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases localization EXP Capsaicin results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr15:33,256,912...33,284,522 JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression ISO Capsaicin results in increased expression of NFE2 mRNA CTD PMID:17603282 NCBI chr 7:134,382,758...134,395,364 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases localization		 ISO Acetylcysteine inhibits the reaction [Capsaicin results in increased localization of NFE2L2 protein] CTD PMID:17979524 NCBI chr 3:81,001,529...81,031,165 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression
multiple interactions		 ISO Capsaicin affects the expression of NFKB1 mRNA
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]		 CTD PMID:19502594 PMID:22171160 NCBI chr 2:226,689,745...226,805,897 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases localization
increases phosphorylation
decreases degradation		 ISO 7-oxozeanol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]
Capsaicin results in increased localization of NFKBIA protein
Capsaicin results in decreased degradation of NFKBIA protein		 CTD PMID:12214859 PMID:16540674 PMID:22171160 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Ngf nerve growth factor multiple interactions
increases response to substance
increases expression
decreases expression		 ISO
EXP		 NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
Capsaicin results in increased expression of NGF protein
Capsaicin results in decreased expression of NGF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]; bisindolylmaleimide I inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Promethazine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of NGF protein]; staurosporine aglycone inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGF protein]; U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; U 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]
NGF protein results in increased susceptibility to Capsaicin; NGF results in increased susceptibility to Capsaicin
Capsaicin results in decreased expression of NGF mRNA
bisindolylmaleimide I inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]; KN 62 inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Staurosporine inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; wortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin]		 CTD PMID:9259450 PMID:10683199 PMID:11166474 PMID:12815188 PMID:15265675 More... NCBI chr 2:192,589,580...192,642,971 JBrowse link
G Ngfr nerve growth factor receptor increases expression
multiple interactions
decreases expression		 EXP Capsaicin results in increased expression of NGFR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGFR protein]
Capsaicin results in decreased expression of NGFR mRNA		 CTD PMID:8971780 PMID:22150557 NCBI chr10:81,012,077...81,030,305 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression ISO Capsaicin results in increased expression of NME2 mRNA CTD PMID:21310942 NCBI chr10:79,394,999...79,400,418 JBrowse link
G Nos1 nitric oxide synthase 1 increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in increased expression of NOS1 mRNA; Capsaicin results in increased expression of NOS1 protein
TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]		 CTD PMID:7477891 PMID:10880996 PMID:11576744 PMID:19846903 NCBI chr12:44,276,011...44,456,371 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]
Capsaicin inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]
Capsaicin results in increased expression of NOS2; Capsaicin results in increased expression of NOS2 mRNA; Capsaicin results in increased expression of NOS2 protein
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:10671773 PMID:11576744 PMID:14530214 PMID:15681035 PMID:19846903 More... NCBI chr10:64,313,335...64,349,221 JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]
Capsaicin results in decreased expression of NOS3 mRNA		 CTD PMID:16278290 PMID:18037908 PMID:19846903 NCBI chr 4:11,686,088...11,706,604 JBrowse link
G Nox3 NADPH oxidase 3 multiple interactions
increases expression		 EXP
ISO		 NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]
NOX3 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]
Capsaicin results in increased expression of NOX3 mRNA; Capsaicin results in increased expression of NOX3 protein		 CTD PMID:20712533 NCBI chr 1:44,238,012...44,302,851 JBrowse link
G Nox4 NADPH oxidase 4 affects expression ISO Capsaicin affects the expression of NOX4 mRNA; Capsaicin affects the expression of NOX4 protein CTD PMID:34939720 NCBI chr 1:150,313,736...150,491,480 JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Capsaicin results in increased expression of NPC1 mRNA CTD PMID:18533110 PMID:36044967 NCBI chr18:3,379,482...3,425,100 JBrowse link
G Npy neuropeptide Y multiple interactions EXP Capsaicin inhibits the reaction [NPY protein affects the susceptibility to Potassium] CTD PMID:18055875 NCBI chr 4:80,212,111...80,219,310 JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions
increases response to substance		 EXP neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [NPY1R protein results in increased susceptibility to Capsaicin] CTD PMID:16714086 NCBI chr16:27,804,416...27,814,070 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
decreases expression		 ISO
EXP		 Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of NQO1 protein]
Capsaicin results in increased expression of NQO1 mRNA
Capsaicin results in decreased expression of NQO1 protein		 CTD PMID:10880996 PMID:17979524 PMID:19449198 PMID:33512557 NCBI chr19:52,205,374...52,220,267 JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of NQO2 protein] CTD PMID:20359164 NCBI chr17:30,909,482...30,938,725 JBrowse link
G Nrp1 neuropilin 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NRP1 protein] CTD PMID:22150557 NCBI chr19:73,256,557...73,411,705 JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions
decreases expression		 ISO
EXP		 NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
Capsaicin results in decreased expression of NTRK1 mRNA		 CTD PMID:8971780 PMID:9259450 PMID:17324588 NCBI chr 2:175,534,844...175,551,664 JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Capsaicin results in increased expression of NUPR1 mRNA CTD PMID:36044967 NCBI chr 1:190,643,866...190,645,901 JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of OGDH] CTD PMID:18023135 NCBI chr14:81,150,021...81,217,479 JBrowse link
G Olig1 oligodendrocyte transcription factor 1 increases expression EXP Capsaicin results in increased expression of OLIG1 mRNA CTD PMID:20349343 NCBI chr11:30,514,379...30,516,521 JBrowse link
G Olr1271 olfactory receptor 1271 increases expression EXP Capsaicin results in increased expression of OLR1271 mRNA CTD PMID:16278290 NCBI chr 8:39,127,409...39,131,889 JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions EXP OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17640294 NCBI chr 3:189,209,495...189,225,406 JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein] CTD PMID:12406535 NCBI chr 1:45,565,371...45,818,722 JBrowse link
G Optn optineurin increases expression ISO Capsaicin results in increased expression of OPTN mRNA CTD PMID:36044967 NCBI chr17:73,209,572...73,260,251 JBrowse link
G Or2ak6e olfactory receptor family 2 subfamily AK member 6E multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of OR2AK6E protein] CTD PMID:20359164 NCBI chr10:43,072,884...43,073,804 JBrowse link
G P22k15 cystatin related protein 2 decreases expression EXP Capsaicin results in decreased expression of P22K15 mRNA CTD PMID:16278290 NCBI chr 3:136,960,300...136,967,358 JBrowse link
G P2ry2 purinergic receptor P2Y2 affects response to substance
multiple interactions		 ISO P2RY2 protein affects the susceptibility to Capsaicin
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]		 CTD PMID:18343036 NCBI chr 1:164,764,119...164,779,578 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases ADP-ribosylation
increases expression		 ISO Capsaicin results in increased cleavage of PARP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]; Caffeine promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein; pifithrin promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]		 CTD PMID:17295509 PMID:17505005 PMID:19855437 PMID:22200406 PMID:22226932 NCBI chr13:94,839,484...94,871,295 JBrowse link
G Pclaf PCNA clamp associated factor increases expression EXP Capsaicin results in increased expression of PCLAF mRNA CTD PMID:20349343 NCBI chr 8:66,420,606...66,432,994 JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP Capsaicin results in increased expression of PCOLCE mRNA CTD PMID:16278290 NCBI chr12:19,084,191...19,090,508 JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 decreases expression EXP Capsaicin results in decreased expression of PCSK5 mRNA CTD PMID:16278290 NCBI chr 1:214,837,847...215,267,626 JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Capsaicin results in decreased expression of PCTP mRNA CTD PMID:18533110 NCBI chr10:74,808,887...74,856,260 JBrowse link
G Pde2a phosphodiesterase 2A decreases expression EXP Capsaicin results in decreased expression of PDE2A mRNA CTD PMID:20349343 NCBI chr 1:155,823,590...155,915,434 JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression
multiple interactions		 EXP Capsaicin results in increased expression of PDGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]		 CTD PMID:22150557 NCBI chr12:15,645,549...15,667,056 JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression EXP Capsaicin results in decreased expression of PDX1 mRNA CTD PMID:16278290 NCBI chr12:12,793,957...12,799,156 JBrowse link
G Pdyn prodynorphin increases expression
multiple interactions		 EXP Capsaicin results in increased expression of PDYN mRNA; Capsaicin results in increased expression of PDYN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of PDYN protein]		 CTD PMID:15385614 NCBI chr 3:137,354,161...137,366,503 JBrowse link
G Pdzd2 PDZ domain containing 2 increases expression EXP Capsaicin results in increased expression of PDZD2 mRNA CTD PMID:16278290 NCBI chr 2:61,384,614...61,770,516 JBrowse link
G Per2 period circadian regulator 2 increases expression EXP Capsaicin results in increased expression of PER2 mRNA CTD PMID:24746025 NCBI chr 9:99,454,828...99,497,069 JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression
decreases expression		 ISO
EXP		 Capsaicin results in increased expression of PGM1 mRNA; Capsaicin results in increased expression of PGM1 protein
Capsaicin results in decreased expression of PGM1 mRNA		 CTD PMID:19891501 PMID:20349343 NCBI chr 5:119,710,734...119,770,159 JBrowse link
G Phb2 prohibitin 2 multiple interactions ISO Capsaicin binds to and results in increased localization of PHB2 protein CTD PMID:19116139 NCBI chr 4:157,517,662...157,522,268 JBrowse link
G Phox2a paired-like homeobox 2a increases expression EXP Capsaicin results in increased expression of PHOX2A mRNA CTD PMID:16278290 NCBI chr 1:156,178,754...156,183,118 JBrowse link
G Phykpl 5-phosphohydroxy-L-lysine phospho-lyase increases expression EXP Capsaicin results in increased expression of PHYKPL mRNA CTD PMID:20349343 NCBI chr10:35,839,965...35,863,631 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin] CTD PMID:17324588 NCBI chr 2:34,612,946...34,697,660 JBrowse link
G Pink1 PTEN induced kinase 1 increases expression ISO Capsaicin results in increased expression of PINK1 mRNA CTD PMID:36044967 NCBI chr 5:155,813,838...155,825,950 JBrowse link
G Pla2g15 phospholipase A2, group XV decreases expression EXP Capsaicin results in decreased expression of PLA2G15 mRNA CTD PMID:20349343 NCBI chr19:34,050,685...34,068,070 JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions
increases phosphorylation		 ISO SB 203580 inhibits the reaction [Capsaicin results in increased phosphorylation of PLA2G4A protein] CTD PMID:19959817 NCBI chr13:64,427,921...64,572,352 JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Capsaicin results in increased expression of PLAU mRNA CTD PMID:21310942 NCBI chr15:3,505,485...3,511,987 JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Capsaicin results in increased expression of PLAUR mRNA CTD PMID:21310942 NCBI chr 1:89,181,363...89,196,308 JBrowse link
G Plcb3 phospholipase C beta 3 decreases expression EXP Capsaicin results in decreased expression of PLCB3 mRNA CTD PMID:20349343 NCBI chr 1:204,143,257...204,160,384 JBrowse link
G Plin2 perilipin 2 affects expression
multiple interactions		 EXP Capsaicin affects the expression of PLIN2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]		 CTD PMID:22150557 NCBI chr 5:106,202,634...106,258,748 JBrowse link
G Plp1 proteolipid protein 1 increases expression EXP Capsaicin results in increased expression of PLP1 mRNA CTD PMID:20349343 NCBI chr  X:104,933,921...104,993,317 JBrowse link
G Pnisr PNN interacting serine and arginine rich protein increases expression EXP Capsaicin results in increased expression of PNISR mRNA CTD PMID:20349343 NCBI chr 5:40,190,214...40,219,619 JBrowse link
G Polb DNA polymerase beta decreases expression EXP Capsaicin results in decreased expression of POLB mRNA CTD PMID:16278290 NCBI chr16:69,379,438...69,402,710 JBrowse link
G Polr2f RNA polymerase II, I and III subunit F increases expression EXP Capsaicin results in increased expression of POLR2F mRNA CTD PMID:16278290 NCBI chr 7:110,712,528...110,724,234 JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; CP 96345 inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Lidocaine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of POMC protein] CTD PMID:2846107 PMID:8925284 PMID:22150557 NCBI chr 6:32,659,137...32,665,175 JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of POR protein] CTD PMID:19449198 NCBI chr12:26,587,674...26,655,612 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases expression		 ISO Capsaicin results in decreased expression of PPARA mRNA
Capsaicin results in increased expression of PPARA mRNA		 CTD PMID:18769453 PMID:19798065 NCBI chr 7:118,712,261...118,780,723 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Capsaicin results in decreased expression of PPARD mRNA CTD PMID:18769453 NCBI chr20:6,300,527...6,365,707 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases activity
decreases expression		 ISO
EXP		 bisphenol A diglycidyl ether inhibits the reaction [Capsaicin results in increased activity of PPARG protein]
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]
Capsaicin results in decreased expression of PPARG protein
Capsaicin results in decreased expression of PPARG mRNA		 CTD PMID:15383218 PMID:17295509 PMID:18769453 PMID:20359164 NCBI chr 4:150,095,743...150,221,104 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of PPARGC1A mRNA
Capsaicin promotes the reaction [Dietary Fats results in increased expression of PPARGC1A mRNA]		 CTD PMID:19798065 PMID:20359164 NCBI chr14:63,073,505...63,729,215 JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO Capsaicin inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein] CTD PMID:21474433 NCBI chr 7:45,368,922...45,480,158 JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17590514 NCBI chr 2:227,839,058...228,113,560 JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit increases expression EXP Capsaicin results in increased expression of PPP5C mRNA CTD PMID:16278290 NCBI chr 1:86,818,297...86,842,505 JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of PRDX1 protein] CTD PMID:20359164 NCBI chr 5:135,383,906...135,399,504 JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO Capsaicin results in increased expression of PRDX6 protein CTD PMID:18991268 NCBI chr13:73,528,746...73,539,295 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases phosphorylation
increases expression		 ISO
EXP		 [Genistein co-treated with Capsaicin] results in increased activity of PRKAA1 protein; acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA1 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]
Capsaicin results in increased phosphorylation of PRKAA1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]		 CTD PMID:19723084 PMID:22150557 PMID:36044967 NCBI chr 2:55,967,766...56,003,450 JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased phosphorylation of PRKAA2 protein
acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA2 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of PRKAA2 protein]		 CTD PMID:36044967 NCBI chr 5:125,036,945...125,109,010 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases phosphorylation ISO Capsaicin results in increased phosphorylation of PRKACA protein CTD PMID:21908651 NCBI chr19:41,059,843...41,083,189 JBrowse link
G Prkca protein kinase C, alpha increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in increased expression of PRKCA mRNA; Capsaicin results in increased expression of PRKCA protein
bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]
chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]		 CTD PMID:18752301 PMID:21474332 NCBI chr10:93,388,991...93,787,617 JBrowse link
G Prkcd protein kinase C, delta increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PRKCD protein
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]		 CTD PMID:22171160 NCBI chr16:5,775,681...5,806,122 JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 6:13,718,050...14,204,931 JBrowse link
G Prkcz protein kinase C, zeta increases response to substance ISO PRKCZ protein alternative form results in increased susceptibility to Capsaicin CTD PMID:27899695 NCBI chr 5:171,101,774...171,212,694 JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO
EXP		 PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]		 CTD PMID:15471852 NCBI chr 6:73,460,640...73,774,433 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
increases phosphorylation		 ISO 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]; Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein] CTD PMID:22226932 NCBI chr11:98,544,952...98,762,499 JBrowse link
G Prlr prolactin receptor increases expression
multiple interactions		 EXP Capsaicin results in increased expression of PRLR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of PRLR protein]		 CTD PMID:22150557 NCBI chr 2:60,861,391...61,051,883 JBrowse link
G Prok1 prokineticin 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PROK1 protein] CTD PMID:22150557 NCBI chr 2:194,850,539...194,859,343 JBrowse link
G Prok2 prokineticin 2 increases response to substance ISO PROK2 protein results in increased susceptibility to Capsaicin CTD PMID:17107623 NCBI chr 4:132,346,681...132,361,754 JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions
increases response to substance		 ISO PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]
PROKR1 protein results in increased susceptibility to Capsaicin		 CTD PMID:16793879 NCBI chr 4:120,022,301...120,033,367 JBrowse link
G Prokr2 prokineticin receptor 2 decreases expression EXP Capsaicin results in decreased expression of PROKR2 mRNA CTD PMID:16278290 NCBI chr 3:119,624,738...119,639,442 JBrowse link
G Ptgir prostaglandin I2 receptor increases response to substance ISO PTGIR results in increased susceptibility to Capsaicin CTD PMID:15985616 NCBI chr 1:86,707,690...86,710,073 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 Capsaicin promotes the reaction [Genistein results in decreased expression of PTGS2 protein]
Capsaicin results in increased expression of PTGS2 mRNA; Capsaicin results in increased expression of PTGS2 protein
[Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Botulinum Toxins, Type A inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
Capsaicin results in decreased expression of PTGS2 mRNA
Capsaicin results in decreased expression of PTGS2 protein		 CTD PMID:11125845 PMID:14530214 PMID:17141941 PMID:17719033 PMID:19723084 More... NCBI chr13:64,714,063...64,722,320 JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein] CTD PMID:21462327 NCBI chr 7:107,015,730...107,220,865 JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 increases expression ISO Capsaicin results in increased expression of PTPN22 mRNA CTD PMID:36044967 NCBI chr 2:191,366,761...191,414,782 JBrowse link
G Ranbp3l RAN binding protein 3-like increases expression EXP Capsaicin results in increased expression of RANBP3L mRNA CTD PMID:20349343 NCBI chr 2:58,057,887...58,113,158 JBrowse link
G Rarres2 retinoic acid receptor responder 2 multiple interactions ISO RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:20383154 NCBI chr 4:77,522,549...77,525,733 JBrowse link
G Rbm5 RNA binding motif protein 5 increases expression EXP Capsaicin results in increased expression of RBM5 mRNA CTD PMID:20349343 NCBI chr 8:117,298,866...117,328,107 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity
decreases localization		 ISO Capsaicin results in decreased activity of RELA protein
Capsaicin results in decreased localization of RELA protein		 CTD PMID:12214859 PMID:16540674 PMID:17719033 NCBI chr 1:212,354,336...212,364,815 JBrowse link
G Retn resistin increases expression
multiple interactions		 EXP Capsaicin results in increased expression of RETN protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETN protein]		 CTD PMID:22150557 NCBI chr12:6,508,653...6,511,115 JBrowse link
G Retnlb resistin like beta multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETNLB protein] CTD PMID:22150557 NCBI chr11:51,983,482...51,985,368 JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO Capsaicin results in increased expression of RIPK2 mRNA CTD PMID:19502594 NCBI chr 5:34,428,573...34,459,808 JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO Capsaicin results in increased expression of RPS6KA3 protein CTD PMID:18991268 NCBI chr  X:39,325,926...39,432,017 JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
increases phosphorylation		 ISO Capsaicin results in decreased phosphorylation of RPS6KB1 protein
Capsaicin results in increased phosphorylation of RPS6KB1 mRNA		 CTD PMID:22226932 PMID:36044967 NCBI chr10:71,817,794...71,865,211 JBrowse link
G Rragc Ras-related GTP binding C increases expression ISO Capsaicin results in increased expression of RRAGC mRNA CTD PMID:36044967 NCBI chr 5:141,433,014...141,452,546 JBrowse link
G Rragd Ras-related GTP binding D increases expression ISO Capsaicin results in increased expression of RRAGD mRNA CTD PMID:36044967 NCBI chr 5:52,170,234...52,205,700 JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA] CTD PMID:19825429 NCBI chr20:4,598,475...4,604,118 JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Capsaicin results in decreased expression of RXRA mRNA CTD PMID:18769453 NCBI chr 3:31,387,892...31,474,415 JBrowse link
G Rxrb retinoid X receptor beta decreases expression ISO Capsaicin results in decreased expression of RXRB mRNA CTD PMID:18769453 NCBI chr20:4,816,813...4,823,267 JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Capsaicin results in increased expression of S100A4 mRNA CTD PMID:21310942 NCBI chr 2:178,388,529...178,390,838 JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Capsaicin results in increased expression of S100B protein CTD PMID:17635592 NCBI chr20:12,372,345...12,381,159 JBrowse link
G S100g S100 calcium binding protein G increases expression EXP Capsaicin results in increased expression of S100G mRNA CTD PMID:16278290 NCBI chr  X:31,705,853...31,708,422 JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
increases response to substance		 ISO SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
SCN10A results in increased susceptibility to Capsaicin		 CTD PMID:12351708 PMID:18845912 NCBI chr 8:128,228,424...128,340,749 JBrowse link
G Scp2 sterol carrier protein 2 decreases expression ISO Capsaicin results in decreased expression of SCP2 mRNA CTD PMID:18533110 NCBI chr 5:128,035,714...128,110,015 JBrowse link
G Sele selectin E increases expression
multiple interactions		 EXP Capsaicin results in increased expression of SELE protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELE protein]		 CTD PMID:22150557 NCBI chr13:78,935,997...78,945,905 JBrowse link
G Sell selectin L increases expression
multiple interactions		 EXP Capsaicin results in increased expression of SELL protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELL protein]		 CTD PMID:22150557 NCBI chr13:78,950,100...78,969,604 JBrowse link
G Senp5 SUMO specific peptidase 5 decreases expression EXP Capsaicin results in decreased expression of SENP5 mRNA CTD PMID:20349343 NCBI chr11:68,784,699...68,819,569 JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Capsaicin results in decreased expression of SERPINE1 mRNA CTD PMID:21310942 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Sesn1 sestrin 1 increases expression ISO Capsaicin results in increased expression of SESN1 mRNA CTD PMID:36044967 NCBI chr20:46,876,918...46,970,010 JBrowse link
G Sesn3 sestrin 3 increases expression ISO Capsaicin results in increased expression of SESN3 mRNA CTD PMID:36044967 NCBI chr 8:19,415,307...19,470,943 JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression EXP Capsaicin results in increased expression of SFPQ mRNA CTD PMID:20349343 NCBI chr 5:139,338,034...139,353,476 JBrowse link
G Sh3bp5 SH3-domain binding protein 5 decreases expression EXP Capsaicin results in decreased expression of SH3BP5 mRNA CTD PMID:16278290 NCBI chr16:6,583,462...6,678,344 JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression EXP Capsaicin results in increased expression of SH3KBP1 mRNA CTD PMID:16278290 NCBI chr  X:38,686,530...39,031,658 JBrowse link
G Sirt1 sirtuin 1 affects expression ISO Capsaicin affects the expression of SIRT1 mRNA; Capsaicin affects the expression of SIRT1 protein CTD PMID:34939720 NCBI chr20:25,305,953...25,328,000 JBrowse link
G Slc12a1 solute carrier family 12 member 1 multiple interactions
increases expression		 EXP [Capsaicin co-treated with Sodium Chloride, Dietary] results in increased expression of SLC12A1 mRNA
Capsaicin results in increased expression of SLC12A1 mRNA		 CTD PMID:17414671 NCBI chr 3:112,406,140...112,482,913 JBrowse link
G Slc12a2 solute carrier family 12 member 2 affects response to substance ISO SLC12A2 affects the susceptibility to Capsaicin CTD PMID:15135928 NCBI chr18:51,348,282...51,416,448 JBrowse link
G Slc16a10 solute carrier family 16 member 10 decreases expression EXP Capsaicin results in decreased expression of SLC16A10 mRNA CTD PMID:16278290 NCBI chr20:43,454,819...43,567,839 JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Capsaicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019 JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Capsaicin results in increased expression of SLC2A4 mRNA CTD PMID:19798065 NCBI chr10:55,164,721...55,170,289 JBrowse link
G Slc37a1 solute carrier family 37 member 1 decreases expression EXP Capsaicin results in decreased expression of SLC37A1 mRNA CTD PMID:20349343 NCBI chr20:9,360,501...9,433,895 JBrowse link
G Slit1 slit guidance ligand 1 increases expression EXP Capsaicin results in increased expression of SLIT1 mRNA CTD PMID:16278290 NCBI chr 1:240,409,559...240,558,127 JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases response to substance
multiple interactions		 ISO Capsaicin results in increased expression of SOD2 protein modified form
SOD2 results in decreased susceptibility to Capsaicin
phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]		 CTD PMID:19129394 NCBI chr 1:50,043,323...50,050,168 JBrowse link
G Sostdc1 sclerostin domain containing 1 increases expression EXP Capsaicin results in increased expression of SOSTDC1 mRNA CTD PMID:20349343 NCBI chr 6:58,778,623...58,782,797 JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases localization		 ISO Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]
Capsaicin results in increased localization of SP1 protein		 CTD PMID:22200406 NCBI chr 7:135,419,864...135,450,513 JBrowse link
G Spi1 Spi-1 proto-oncogene increases expression ISO Capsaicin results in increased expression of SPI1 mRNA CTD PMID:17603282 NCBI chr 3:77,059,744...77,093,730 JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Sumatriptan promotes the reaction [Capsaicin results in increased expression of SPP1 protein] CTD PMID:22150557 NCBI chr14:5,613,569...5,620,695 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases activity		 ISO
EXP		 Capsaicin results in decreased phosphorylation of and results in decreased activity of SRC protein
AG 1879 inhibits the reaction [Capsaicin results in increased activity of SRC protein]
SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]		 CTD PMID:17505005 PMID:20660715 PMID:21340460 NCBI chr 3:166,511,616...166,559,463 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Capsaicin results in increased expression of SREBF1 mRNA CTD PMID:36044967 NCBI chr10:45,507,152...45,529,164 JBrowse link
G Sst somatostatin multiple interactions
increases secretion
decreases expression
increases expression		 EXP
ISO		 AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]
Capsaicin results in increased secretion of SST protein
Capsaicin results in decreased expression of SST mRNA		 CTD PMID:8093704 PMID:8093880 PMID:9932722 PMID:16938409 PMID:19296048 More... NCBI chr11:76,956,896...76,958,173 JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression
multiple interactions
increases response to substance		 EXP
ISO		 Capsaicin results in increased expression of STAT1 mRNA; Capsaicin results in increased expression of STAT1 protein
Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein
STAT1 results in increased susceptibility to Capsaicin
Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein; CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]		 CTD PMID:14530214 PMID:20712533 NCBI chr 9:56,911,522...56,951,926 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases phosphorylation
affects localization		 ISO
EXP		 Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein; pervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]
Capsaicin results in increased phosphorylation of STAT3 protein
Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein]
Capsaicin affects the localization of STAT3 protein		 CTD PMID:16788306 PMID:17505005 PMID:19285962 NCBI chr10:86,311,528...86,363,513 JBrowse link
G Steap3 STEAP3 metalloreductase multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of STEAP3 protein] CTD PMID:20359164 NCBI chr13:33,904,710...33,950,100 JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 decreases expression EXP Capsaicin results in decreased expression of SUV39H1 mRNA CTD PMID:16278290 NCBI chr  X:146,828,818...146,831,485 JBrowse link
G Syn2 synapsin II increases response to substance ISO SYN2 results in increased susceptibility to Capsaicin CTD PMID:18701217 NCBI chr 4:148,178,846...148,347,010 JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 affects response to substance ISO SYNGAP1 affects the susceptibility to Capsaicin CTD PMID:21525372 NCBI chr20:5,026,366...5,056,659 JBrowse link
G Syt7 synaptotagmin 7 increases expression EXP Capsaicin results in increased expression of SYT7 mRNA CTD PMID:16278290 NCBI chr 1:207,031,359...207,093,787 JBrowse link
G Tac1 tachykinin, precursor 1 affects expression
decreases activity
decreases expression
decreases secretion
increases secretion
increases expression
multiple interactions		 ISO
EXP		 Capsaicin affects the expression of TAC1 protein
TAC1 protein results in decreased activity of Capsaicin
Capsaicin results in decreased expression of TAC1 mRNA; Capsaicin results in decreased expression of TAC1 protein
Capsaicin results in decreased secretion of TAC1 protein
Capsaicin results in increased secretion of TAC1 protein; Capsaicin results in increased secretion of TAC1 protein alternative form
Capsaicin results in increased expression of TAC1 mRNA; Capsaicin results in increased expression of TAC1 protein
[Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]; SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]; bisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of TAC1 mRNA]; Capsaicin inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]; Capsaicin results in increased expression of and results in increased secretion of TAC1 protein; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; capsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; cochinchinenin inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; CP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; dragon's blood inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Gabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; Go 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; HU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Iloprost promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Indomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Morphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Pregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; pyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; SB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]
Capsaicin results in increased secretion of TAC1 protein; Capsaicin results in increased secretion of TAC1 protein alternative form; Capsaicin results in increased secretion of TAC1 protein modified form		 CTD PMID:2325850 PMID:2480171 PMID:3412491 PMID:6205719 PMID:7473211 More... NCBI chr 4:36,645,344...36,653,548 JBrowse link
G Tac3 tachykinin precursor 3 decreases expression EXP Capsaicin results in decreased expression of TAC2 mRNA CTD PMID:16278290 NCBI chr 7:63,562,552...63,569,170 JBrowse link
G Tacr1 tachykinin receptor 1 decreases expression
increases expression
multiple interactions
affects expression
increases response to substance		 ISO
EXP		 Capsaicin results in decreased expression of TACR1 mRNA; Capsaicin results in decreased expression of TACR1 protein
Capsaicin results in increased expression of TACR1 protein
Capsaicin affects the reaction [Vehicle Emissions affects the expression of TACR1 mRNA]; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR1 mRNA]; Capsaicin promotes the reaction [Vehicle Emissions results in increased expression of TACR1 protein]
Capsaicin affects the expression of TACR1 mRNA
TACR1 results in increased susceptibility to Capsaicin		 CTD PMID:10360863 PMID:11166975 PMID:13680092 PMID:18441096 PMID:19399481 More... NCBI chr 4:116,478,617...116,647,492 JBrowse link
G Tacr2 tachykinin receptor 2 increases response to substance
multiple interactions
decreases expression		 ISO
EXP		 TACR2 gene polymorphism results in increased susceptibility to Capsaicin
Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR2 mRNA]
Capsaicin results in decreased expression of TACR2 mRNA		 CTD PMID:16278290 PMID:16893949 PMID:19399481 NCBI chr20:30,208,907...30,223,446 JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor increases expression
multiple interactions		 EXP Capsaicin results in increased expression of TAL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]		 CTD PMID:22150557 NCBI chr 5:128,586,776...128,600,976 JBrowse link
G Tek TEK receptor tyrosine kinase increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in increased expression of TEK protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TEK protein]
Capsaicin results in increased expression of TEK mRNA		 CTD PMID:21310942 PMID:22150557 NCBI chr 5:114,722,815...114,849,535 JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Capsaicin results in increased expression of TGFA mRNA; Capsaicin results in increased expression of TGFA protein CTD PMID:11989832 NCBI chr 4:120,175,549...120,258,342 JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in decreased expression of TGFB1 mRNA
Capsaicin results in increased expression of TGFB1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]		 CTD PMID:18533110 PMID:22150557 NCBI chr 1:90,324,312...90,340,627 JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of TGFB2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]		 CTD PMID:22150557 NCBI chr13:98,160,075...98,261,771 JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein] CTD PMID:22150557 NCBI chr 6:111,435,170...111,457,646 JBrowse link
G Thop1 thimet oligopeptidase 1 increases expression EXP Capsaicin results in increased expression of THOP1 mRNA CTD PMID:16278290 NCBI chr 7:9,283,617...9,295,957 JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of TIMP1 mRNA
Capsaicin results in increased expression of TIMP1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]		 CTD PMID:21310942 PMID:22150557 NCBI chr  X:3,766,509...3,772,578 JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of TIMP2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]		 CTD PMID:22150557 NCBI chr10:104,041,604...104,089,214 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of TIMP3 mRNA
Capsaicin results in increased expression of TIMP3 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]		 CTD PMID:21310942 PMID:22150557 NCBI chr 7:19,408,539...19,459,558 JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions		 EXP Capsaicin results in increased expression of TLR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]		 CTD PMID:22150557 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression ISO Capsaicin results in decreased expression of TM7SF2 mRNA CTD PMID:18533110 NCBI chr 1:203,355,930...203,360,287 JBrowse link
G Tmem37 transmembrane protein 37 increases expression EXP Capsaicin results in increased expression of TMEM37 mRNA CTD PMID:16278290 NCBI chr13:31,184,322...31,191,477 JBrowse link
G Tnc tenascin C decreases expression ISO Capsaicin results in decreased expression of TNC mRNA CTD PMID:33512557 NCBI chr 5:82,391,340...82,476,197 JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression
decreases expression
multiple interactions
increases secretion
increases response to substance
affects response to substance		 ISO
EXP		 Capsaicin results in decreased secretion of TNF protein
Capsaicin results in increased expression of TNF mRNA; Capsaicin results in increased expression of TNF protein
Capsaicin results in decreased expression of TNF mRNA; Capsaicin results in decreased expression of TNF protein
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of TNF mRNA; [Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Capsaicin] results in increased expression of TNF protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of TNF mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in decreased expression of TNF protein]; Capsaicin inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]; capsazepine inhibits the reaction [Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of TNF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNF protein]
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]
Capsaicin results in increased secretion of TNF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TNF protein]
TNF protein results in increased susceptibility to Capsaicin
TNF protein affects the susceptibility to Capsaicin		 CTD PMID:11408036 PMID:11744139 PMID:12024109 PMID:12034025 PMID:15265675 More... NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Capsaicin results in increased expression of TNFRSF10A mRNA; Capsaicin results in increased expression of TNFRSF10A protein CTD PMID:19502594 PMID:19846903 NCBI chr15:51,249,883...51,278,091 JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 affects expression
multiple interactions		 EXP Capsaicin affects the expression of TNFRSF19 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]		 CTD PMID:22150557 NCBI chr15:39,268,305...39,334,566 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TNFRSF1A mRNA
capsazepine inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]		 CTD PMID:19531269 PMID:21310942 NCBI chr 4:159,837,119...159,849,817 JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO Capsaicin results in increased expression of TNFRSF25 mRNA CTD PMID:19502594 NCBI chr 5:162,621,669...162,626,341 JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases expression
increases response to substance
increases activity		 ISO
EXP		 [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]; Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; TNFRSF10B mutant form inhibits the reaction [Capsaicin results in increased susceptibility to TNFSF10 protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]
Capsaicin results in increased expression of TNFSF10 mRNA; Capsaicin results in increased expression of TNFSF10 protein
Capsaicin results in increased activity of TNFSF10 protein		 CTD PMID:19939880 PMID:22150557 PMID:22200406 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tom1 target of myb1 membrane trafficking protein decreases expression EXP Capsaicin results in decreased expression of TOM1 mRNA CTD PMID:20349343 NCBI chr19:13,405,482...13,440,384 JBrowse link
G Tp53 tumor protein p53 decreases degradation
affects response to substance
increases phosphorylation
multiple interactions
increases expression
increases degradation		 ISO Capsaicin results in decreased degradation of TP53 protein
TP53 affects the susceptibility to Capsaicin
Capsaicin results in increased phosphorylation of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; Caffeine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Capsaicin promotes the reaction [resveratrol results in increased expression of TP53 protein]; Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; pyrazolanthrone inhibits the reaction [Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of TP53 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]; TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; Tunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein]
Capsaicin results in increased expression of TP53 mRNA; Capsaicin results in increased expression of TP53 protein
Capsaicin results in increased expression of TRP53		 CTD PMID:9461043 PMID:14871840 PMID:16540674 PMID:17292493 PMID:18991268 More... NCBI chr10:54,798,871...54,810,300 JBrowse link
G Tp53inp2 tumor protein p53 inducible nuclear protein 2 increases expression ISO Capsaicin results in increased expression of TP53INP2 mRNA CTD PMID:36044967 NCBI chr 3:143,881,427...143,890,104 JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Capsaicin results in increased expression of TPI1 mRNA; Capsaicin results in increased expression of TPI1 protein CTD PMID:19891501 NCBI chr 4:159,301,558...159,305,088 JBrowse link
G Traf3 Tnf receptor-associated factor 3 increases expression ISO Capsaicin results in increased expression of TRAF3 mRNA CTD PMID:19502594 NCBI chr 6:136,025,097...136,128,363 JBrowse link
G Traf4 Tnf receptor associated factor 4 increases expression ISO Capsaicin results in increased expression of TRAF4 mRNA CTD PMID:19502594 NCBI chr10:63,054,169...63,060,284 JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression EXP Capsaicin results in increased expression of TRAFD1 mRNA CTD PMID:16278290 NCBI chr12:40,826,251...40,840,169 JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Capsaicin results in increased expression of TRIB3 mRNA CTD PMID:36044967 NCBI chr 3:161,269,939...161,275,533 JBrowse link
G Triml1 tripartite motif family-like 1 increases expression ISO Capsaicin results in increased expression of TRIML1 mRNA CTD PMID:36044967 NCBI chr16:48,994,968...49,005,343 JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity
decreases expression		 EXP
ISO		 Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]
Capsaicin results in increased activity of TRPA1 protein
Capsaicin results in decreased expression of TRPA1 mRNA		 CTD PMID:17590514 PMID:18079164 PMID:29054683 NCBI chr 5:9,163,060...9,217,325 JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 increases expression EXP Capsaicin results in increased expression of TRPC5 mRNA CTD PMID:16278290 NCBI chr  X:107,946,163...108,230,991 JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression
increases activity		 EXP
ISO		 Capsaicin results in decreased expression of TRPM8 mRNA
Capsaicin results in increased activity of TRPM8 protein		 CTD PMID:18079164 PMID:29054683 NCBI chr 9:96,315,567...96,437,959 JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects response to substance
decreases expression
increases response to substance
increases activity
increases expression
affects binding
affects localization
multiple interactions
decreases response to substance		 ISO
EXP		 TRPV1 protein affects the susceptibility to Capsaicin; TRPV1 protein polymorphism affects the susceptibility to Capsaicin analog
Capsaicin results in decreased expression of TRPV1 mRNA; Capsaicin results in decreased expression of TRPV1 protein
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 protein results in increased susceptibility to Capsaicin analog
Capsaicin results in increased activity of TRPV1 protein
Capsaicin results in increased expression of TRPV1 mRNA; Capsaicin results in increased expression of TRPV1 protein
Capsaicin results in increased activity of TRPV1; Capsaicin results in increased activity of TRPV1 protein
Capsaicin binds to TRPV1 protein
Capsaicin affects the localization of TRPV1 protein
Capsaicin analog results in increased activity of TRPV1 protein; Capsaicin results in increased activity of TRPV1; Capsaicin results in increased activity of TRPV1 protein
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]]; capsazepine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Egtazic Acid inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]; Xenon inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 2,3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 2,4-bis(4'-fluorophenethylamino)-6-(3'-(N,N-dimethylamino)propylamino)-1,3,5-triazine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-amino-5-((2-((2-methoxyethyl)amino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)oxy)quinoxalin-2(1H)-one inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and affects the activity of TRPV1 protein] which results in increased secretion of Adenosine Triphosphate; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; Acrylamide analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Amitriptyline inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Bupivacaine affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Cadmium inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TRPV1 mRNA]; Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [TRPV1 protein binds to TRPV1 protein]; capsazepine inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Cobalt inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; Copper inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Docosahexaenoic Acids promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Fulvestrant inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; gamma-Linolenic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; geldanamycin affects the reaction [Capsaicin results in increased activity of TRPV1]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin binds to TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; KJM 429 inhibits the reaction [Capsaicin binds to TRPV1 protein]; Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; MCS-18 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-((4-(((3-(6-((2-amino-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)) -6-(trifluoromethyl)pyridin-2-yl)amino)methyl)-2-fluorophenyl)methanesulfonamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Nickel inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Octoxynol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Tamoxifen inhibits the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Tamoxifen inhibits the reaction [Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; tert-butyl-2-(6-((2-(acetylamino)-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenylcarbamate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetracaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Capsaicin binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Linolenic Acids inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 results in increased susceptibility to Capsaicin
TRPV1 protein mutant form results in decreased susceptibility to Capsaicin; TRPV1 results in decreased susceptibility to Capsaicin		 CTD PMID:11140687 PMID:11278420 PMID:11358970 PMID:11606325 PMID:11930156 More... NCBI chr10:58,349,936...58,375,021 JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression EXP Capsaicin results in increased expression of TRPV4 mRNA CTD PMID:16278290 NCBI chr12:47,599,161...47,638,143 JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
increases response to substance		 ISO TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
TRPV6 protein results in increased susceptibility to Capsaicin		 CTD PMID:17292493 NCBI chr 4:70,507,347...70,523,013 JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Capsaicin results in decreased expression of TXNIP mRNA CTD PMID:33512557 NCBI chr 2:186,781,933...186,785,736 JBrowse link
G Ucp1 uncoupling protein 1 decreases expression
multiple interactions		 EXP Capsaicin results in decreased expression of UCP1 mRNA; Capsaicin results in decreased expression of UCP1 protein
Capsaicin promotes the reaction [Dietary Fats results in increased expression of UCP1 mRNA]		 CTD PMID:18079164 PMID:20359164 NCBI chr19:41,713,350...41,721,421 JBrowse link
G Ucp2 uncoupling protein 2 affects response to substance
multiple interactions		 ISO
EXP		 UCP2 protein polymorphism affects the susceptibility to Capsaicin analog
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of UCP2 mRNA]		 CTD PMID:19056576 PMID:20359164 NCBI chr 1:164,251,373...164,257,742 JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions EXP Capsaicin inhibits the reaction [Dietary Fats results in increased expression of UCP3 protein] CTD PMID:20517883 NCBI chr 1:154,815,777...154,828,764 JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 9:96,249,143...96,256,264 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 9:96,144,786...96,256,264 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression ISO Capsaicin results in increased expression of ULK1 mRNA CTD PMID:36044967 NCBI chr12:51,511,492...51,537,746 JBrowse link
G Unc13a unc-13 homolog A increases expression EXP Capsaicin results in increased expression of UNC13A mRNA CTD PMID:16278290 NCBI chr16:18,333,910...18,381,813 JBrowse link
G Usp5 ubiquitin specific peptidase 5 decreases expression EXP Capsaicin results in decreased expression of USP5 mRNA CTD PMID:20349343 NCBI chr 4:159,305,927...159,321,345 JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression EXP Capsaicin results in decreased expression of VAMP2 mRNA CTD PMID:20349343 NCBI chr10:54,292,423...54,296,657 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of VCAM1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]		 CTD PMID:9973426 PMID:22150557 NCBI chr 2:206,723,050...206,742,783 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
multiple interactions
decreases activity
increases secretion		 ISO
EXP		 Capsaicin results in decreased expression of VEGFA protein
Capsaicin results in increased expression of VEGFA mRNA
Capsaicin results in increased expression of VEGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of VEGFA protein]
Capsaicin results in decreased activity of VEGFA
Capsaicin results in increased secretion of VEGFA protein		 CTD PMID:12242509 PMID:14744780 PMID:17505005 PMID:21310942 PMID:22150557 NCBI chr 9:22,452,854...22,468,194 JBrowse link
G Vim vimentin multiple interactions
decreases expression		 EXP
ISO		 Capsaicin inhibits the reaction [Dietary Fats results in increased expression of VIM protein]
Capsaicin results in decreased expression of VIM protein		 CTD PMID:20359164 PMID:36044967 NCBI chr17:81,577,261...81,585,746 JBrowse link
G Vip vasoactive intestinal peptide decreases expression
increases expression		 EXP Capsaicin results in decreased expression of VIP mRNA
Capsaicin results in increased expression of VIP mRNA		 CTD PMID:8971780 PMID:20349343 NCBI chr 1:44,470,232...44,478,561 JBrowse link
G Vom1r90 vomeronasal 1 receptor 90 increases expression EXP Capsaicin results in increased expression of VOM1R90 mRNA CTD PMID:16278290 NCBI chr 4:122,139,053...122,148,056 JBrowse link
G Wnt7a Wnt family member 7A decreases expression EXP Capsaicin results in decreased expression of WNT7A mRNA CTD PMID:16278290 NCBI chr 4:123,863,108...123,908,981 JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Capsaicin results in increased expression of ZC3H12A mRNA CTD PMID:36044967 NCBI chr 5:142,661,193...142,670,051 JBrowse link
G Zfp2 zinc finger protein 2 increases expression EXP Capsaicin results in increased expression of ZFP2 mRNA CTD PMID:16278290 NCBI chr10:35,209,187...35,228,849 JBrowse link
G Zfp866 zinc finger protein 866 multiple interactions
increases expression		 EXP [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein] CTD PMID:22150557 NCBI chr16:19,653,966...19,675,968 JBrowse link
dihydrocapsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO dihydrocapsaicin results in increased expression of ATF4 protein CTD PMID:19139269 NCBI chr 7:113,684,681...113,686,739 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO 3-methyladenine promotes the reaction [dihydrocapsaicin results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [3-methyladenine promotes the reaction [dihydrocapsaicin results in increased activity of CASP3 protein]]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [dihydrocapsaicin promotes the reaction [3-methyladenine results in increased activity of CASP3 protein]]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [dihydrocapsaicin results in increased activity of CASP3 protein]; dihydrocapsaicin promotes the reaction [3-methyladenine results in increased activity of CASP3 protein] CTD PMID:18818525 PMID:19139269 NCBI chr16:52,395,539...52,413,794 JBrowse link
G Casp4 caspase 4 multiple interactions ISO dihydrocapsaicin results in increased cleavage of and results in increased activity of CASP4 protein CTD PMID:19139269 NCBI chr 8:10,883,817...10,919,978 JBrowse link
G Casp7 caspase 7 increases activity ISO dihydrocapsaicin results in increased activity of CASP7 protein CTD PMID:19139269 NCBI chr 1:265,442,647...265,481,938 JBrowse link
G Cat catalase multiple interactions
increases expression		 ISO [dihydrocapsaicin results in decreased expression of CAT protein] which results in increased abundance of Reactive Oxygen Species; [dihydrocapsaicin results in increased expression of CAT protein] which results in decreased abundance of Reactive Oxygen Species; CAT protein affects the reaction [dihydrocapsaicin results in decreased abundance of Reactive Oxygen Species]; CAT protein affects the reaction [dihydrocapsaicin results in increased expression of MAP1LC3A protein] CTD PMID:18818525 PMID:20417273 NCBI chr 3:110,297,340...110,329,526 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO dihydrocapsaicin results in increased expression of CDKN1A protein CTD PMID:19139269 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO dihydrocapsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 NCBI chr 8:66,971,261...66,978,149 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO dihydrocapsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 NCBI chr 1:247,879,058...247,916,804 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO dihydrocapsaicin results in decreased activity of CYP2D6 protein CTD PMID:22375877 NCBI chr 7:115,762,662...115,771,832 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP dihydrocapsaicin results in increased expression of CYP2E1 CTD PMID:22375877 NCBI chr 1:205,269,967...205,280,365 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO dihydrocapsaicin results in increased expression of and results in increased activity of DDIT3 protein; pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of DDIT3 protein] CTD PMID:19139269 NCBI chr 7:65,001,695...65,006,517 JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO dihydrocapsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 NCBI chr 6:103,405,880...103,430,549 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO pyrazolanthrone inhibits the reaction [dihydrocapsaicin results in increased expression of ERN1 protein] CTD PMID:19139269 NCBI chr10:91,826,663...91,920,976 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO dihydrocapsaicin results in increased expression of HSPA5 protein CTD PMID:19139269 NCBI chr 3:38,453,016...38,457,475 JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO dihydrocapsaicin results in increased expression of IGF1 protein CTD PMID:17307377 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression		 ISO Amitrole inhibits the reaction [dihydrocapsaicin results in increased expression of MAP1LC3A protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane promotes the reaction [dihydrocapsaicin results in increased expression of MAP1LC3A protein]; CAT protein affects the reaction [dihydrocapsaicin results in increased expression of MAP1LC3A protein] CTD PMID:18818525 NCBI chr 3:164,243,204...164,244,850 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO dihydrocapsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:19139269 NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO dihydrocapsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:19139269 NCBI chr 1:190,797,189...190,803,411 JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO dihydrocapsaicin results in increased phosphorylation of TP53 protein CTD PMID:19139269 NCBI chr10:54,798,871...54,810,300 JBrowse link
nonivamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO nonivamide results in increased expression of ATF3 mRNA
[nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of ATF3 mRNA		 CTD PMID:17332266 NCBI chr13:105,274,103...105,331,653 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression		 ISO [nonivamide binds to and results in increased activity of CCND1 protein] which results in decreased expression of CCND1 mRNA
nonivamide results in decreased expression of CCND1 mRNA; nonivamide results in decreased expression of CCND1 protein		 CTD PMID:17332266 PMID:37989449 NCBI chr 1:209,518,288...209,527,986 JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression		 ISO [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of CCNG2 mRNA
nonivamide results in increased expression of CCNG2 mRNA		 CTD PMID:17332266 NCBI chr14:15,088,694...15,097,190 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO nonivamide results in decreased expression of CDKN1A protein CTD PMID:37989449 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO nonivamide results in increased expression of CXCL2 mRNA CTD PMID:22155782 NCBI chr14:17,465,210...17,467,255 JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO nonivamide results in increased expression of CXCL1 mRNA CTD PMID:22155782 NCBI chr14:17,571,900...17,573,624 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases response to substance
increases expression
affects expression
multiple interactions		 ISO DDIT3 protein results in decreased susceptibility to nonivamide
nonivamide results in increased expression of DDIT3 mRNA; nonivamide results in increased expression of DDIT3 protein
nonivamide affects the expression of DDIT3 mRNA
[nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of DDIT3 mRNA		 CTD PMID:17332266 PMID:21343315 PMID:21949157 NCBI chr 7:65,001,695...65,006,517 JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases phosphorylation
decreases response to substance		 ISO [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of EIF2A protein; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased phosphorylation of EIF2A protein; salubrinal inhibits the reaction [EIF2A protein results in decreased susceptibility to nonivamide]
nonivamide results in increased phosphorylation of EIF2A protein		 CTD PMID:17332266 NCBI chr 2:142,761,303...142,794,767 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression		 ISO [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of GADD45A mRNA
nonivamide results in increased expression of GADD45A mRNA		 CTD PMID:17332266 NCBI chr 4:97,484,497...97,486,799 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 ISO [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of HSPA5 mRNA
nonivamide results in increased expression of HSPA5 mRNA		 CTD PMID:17332266 NCBI chr 3:38,453,016...38,457,475 JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO nonivamide results in increased expression of IGF1 protein CTD PMID:17307377 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Il6 interleukin 6 increases expression ISO nonivamide results in increased expression of IL6 mRNA CTD PMID:22155782 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO nonivamide inhibits the reaction [TNF protein affects the localization of RELA protein modified form] CTD PMID:36847817 NCBI chr 1:212,354,336...212,364,815 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO nonivamide inhibits the reaction [TNF protein affects the localization of RELA protein modified form] CTD PMID:36847817 NCBI chr20:3,626,685...3,629,303 JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions ISO nonivamide inhibits the reaction [Smoke results in increased expression of TRPA1 mRNA] CTD PMID:36847817 NCBI chr 5:9,163,060...9,217,325 JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
increases response to substance		 ISO [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of ATF3 mRNA; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of CCNG2 mRNA; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of DDIT3 mRNA; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of EIF2A protein; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of GADD45A mRNA; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of HSPA5 mRNA; [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased phosphorylation of EIF2A protein; nonivamide binds to and results in increased activity of TRPV1 protein
nonivamide results in increased activity of TRPV1 protein
TRPV1 protein results in increased susceptibility to nonivamide		 CTD PMID:17332266 PMID:21343315 PMID:22155782 PMID:37989449 NCBI chr10:58,349,936...58,375,021 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      biological role 19867
        biochemical role 19577
          metabolite 19563
            capsaicinoid 524
              6'',7''-dihydro-5',5'''-dicapsaicin 0
              capsaicin 522
              dihydrocapsaicin 19
              nonivamide 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19535
                              organochalcogen compound 19296
                                organooxygen compound 19213
                                  carbon oxoacid 18682
                                    carboxylic acid 18679
                                      carboacyl group 17726
                                        univalent carboacyl group 17726
                                          carbamoyl group 17570
                                            carboxamide 17570
                                              monocarboxylic acid amide 15746
                                                fatty amide 830
                                                  capsaicinoid 524
                                                    6'',7''-dihydro-5',5'''-dicapsaicin 0
                                                    capsaicin 522
                                                    dihydrocapsaicin 19
                                                    nonivamide 16
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