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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dioxane
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Accession:CHEBI:46923 term browser browse the term
Definition:Any member of the class of dioxanes that is a cyclohexane in which two carbon atoms are replaced by oxygen atoms.
Synonyms:related_synonym: Formula=C4H8O2


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1,4-dioxane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 increases expression ISO 1,4-dioxane results in increased expression of CCNB1 protein CTD PMID:20025956 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP 1,4-dioxane results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:15490126 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP 1,4-dioxane results in increased expression of and results in increased activity of CYP2B2 protein CTD PMID:15490126 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases activity
increases expression
EXP 1,4-dioxane results in increased expression of and results in increased activity of CYP2E1 protein
1,4-dioxane results in increased activity of CYP2E1 protein
1,4-dioxane results in increased expression of CYP2E1 mRNA
CTD PMID:15490126 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO 1,4-dioxane results in increased expression of HELLS protein CTD PMID:20025956 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO 1,4-dioxane results in increased expression of IL1RL1 protein CTD PMID:20025956 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO 1,4-dioxane results in increased expression of MCM3 protein CTD PMID:20025956 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 1,4-dioxane results in increased expression of MGMT mRNA CTD PMID:22084566 PMID:30155721 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 1,4-dioxane results in increased expression of PCNA mRNA CTD PMID:30155721 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO 1,4-dioxane results in increased expression of PHEX protein CTD PMID:20025956 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO 1,4-dioxane results in increased expression of RAD51AP1 protein CTD PMID:20025956 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 increases expression ISO 1,4-dioxane results in increased expression of SLC9A3R1 protein CTD PMID:22434383 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    chemical entity 19840
      atom 19838
        nonmetal atom 19718
          oxygen atom 19386
            oxygen molecular entity 19386
              organooxygen compound 18847
                oxacycle 17276
                  dioxanes 12
                    dioxane 12
                      1,2-dioxane 0
                      1,3-dioxane 0
                      1,4-dioxane 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19730
                    p-block element atom 19730
                      carbon group element atom 19635
                        carbon atom 19624
                          organic molecular entity 19624
                            organic molecule 19555
                              organic cyclic compound 19364
                                organic heterocyclic compound 18482
                                  organic heteromonocyclic compound 16591
                                    saturated organic heteromonocyclic parent 5809
                                      dioxane 12
                                        1,2-dioxane 0
                                        1,3-dioxane 0
                                        1,4-dioxane 12
paths to the root