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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidazopyridine
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Accession:CHEBI:46908 term browser browse the term
Synonyms:related_synonym: imidazopyridines



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2-Amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO 2-amino-(1,6-dimethylfuro(3,2-e)imidazo(4,5-b))pyridine inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:16533016 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases expression EXP Fadrozole results in decreased expression of ACE protein CTD PMID:18586661 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression EXP Fadrozole results in increased expression of ACE2 protein CTD PMID:18586661 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression EXP Fadrozole results in decreased expression of AGTR1 protein CTD PMID:18586661 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression EXP Fadrozole results in increased expression of AGTR2 protein CTD PMID:18586661 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases activity ISO Fadrozole results in decreased activity of CYP11B1 protein CTD PMID:15743198 PMID:15771425 PMID:15985365 PMID:21341743 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases activity ISO Fadrozole results in decreased activity of CYP11B2 protein CTD PMID:15743198 PMID:15771425 PMID:15985365 PMID:21341743 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity ISO Fadrozole results in decreased activity of CYP17A1 protein CTD PMID:15743198 PMID:15771425 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
increases activity
ISO Fadrozole results in decreased activity of CYP19A1 protein
Genistein inhibits the reaction [Fadrozole results in increased activity of CYP19A1 protein]
CTD PMID:15743198 PMID:15771425 PMID:21341743 PMID:21854827 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO Fadrozole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Fadrozole binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Fadrozole binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO [Dexamethasone co-treated with Fadrozole] inhibits the reaction [Testosterone results in increased expression of TFF1 mRNA]; Fadrozole inhibits the reaction [bisphenol A results in increased expression of TFF1 mRNA]; Fadrozole inhibits the reaction [Testosterone results in increased expression of TFF1 mRNA] CTD PMID:15525692 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
ageladine A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases activity
multiple interactions
EXP Ageladine A results in decreased activity of DYRK1A protein
Ageladine A analog binds to and results in decreased activity of DYRK1A protein
CTD PMID:21413800 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases activity ISO Ageladine A results in decreased activity of MMP14 protein CTD PMID:21413800 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO Ageladine A results in decreased activity of MMP2 protein CTD PMID:21413800 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase decreases activity ISO Ageladine A results in decreased activity of PIM1 protein CTD PMID:21413800 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
Glu-P-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases expression ISO 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in increased expression of AHR protein CTD PMID:27644595 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in increased expression of CYP1A1 mRNA CTD PMID:27644595 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
increases hydroxylation
ISO CYP1A2 protein affects the metabolism of 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole
CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole
CYP1A2 protein results in increased hydroxylation of 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole
CTD PMID:2655891 PMID:14725854 PMID:28160022 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G H2ax H2A.X variant histone increases expression ISO 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in increased expression of H2AX protein modified form CTD PMID:28160022 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO NAT2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole CTD PMID:28160022 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions
decreases activity
ISO 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]
2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in decreased activity of SLC22A2 protein
CTD PMID:30189235 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
decreases activity
ISO 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole inhibits the reaction [SLC22A3 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]
2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in decreased activity of SLC22A3 protein
CTD PMID:30189235 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole CTD PMID:28160022 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
Glu-P-2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases expression ISO Glu-P-2 results in increased expression of AHR protein CTD PMID:27644595 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
increases expression
ISO CYP1A2 protein affects the metabolism of Glu-P-2
CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Glu-P-2
Glu-P-2 results in increased expression of CYP1A2 mRNA
CTD PMID:2655891 PMID:27644595 PMID:28160022 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Glu-P-2 results in increased expression of H2AX protein modified form CTD PMID:28160022 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO NAT2 protein results in increased metabolism of and results in increased susceptibility to Glu-P-2 CTD PMID:28160022 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity
multiple interactions
ISO Glu-P-2 results in decreased activity of SLC22A2 protein
Glu-P-2 inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]
CTD PMID:30189235 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
decreases activity
ISO Glu-P-2 inhibits the reaction [SLC22A3 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]
Glu-P-2 results in decreased activity of SLC22A3 protein
CTD PMID:30189235 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO SULT1A1 protein results in increased metabolism of and results in increased susceptibility to Glu-P-2 CTD PMID:28160022 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
GSK690693 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein]
GSK690693 results in increased phosphorylation of AKT1 protein
GSK690693 results in decreased phosphorylation of AKT1 protein
CTD PMID:30871965 PMID:31445927 PMID:31962201 PMID:35259468 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO GSK690693 results in increased expression of BBC3 protein CTD PMID:35259468 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased expression of BCL2 protein] CTD PMID:30871965 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of CASP3 protein] CTD PMID:30871965 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions
ISO GSK690693 results in decreased phosphorylation of EIF4EBP1 protein
[sunitinib co-treated with GSK690693] results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:22532600 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Fas Fas cell surface death receptor affects response to substance ISO GSK690693 affects the susceptibility to FAS protein CTD PMID:31445927 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO GSK690693 results in decreased phosphorylation of FOXO3 protein CTD PMID:35259468 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO GSK690693 results in decreased phosphorylation of GSK3B protein CTD PMID:31962201 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein] CTD PMID:30871965 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF4 protein CTD PMID:31962201 NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF5 protein CTD PMID:31962201 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF6 protein CTD PMID:31962201 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein] CTD PMID:30871965 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnf tumor necrosis factor increases response to substance ISO GSK690693 results in increased susceptibility to TNF protein CTD PMID:31445927 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions
decreases phosphorylation
ISO [sunitinib co-treated with GSK690693] results in decreased phosphorylation of TSC2 protein
GSK690693 results in decreased phosphorylation of TSC2 protein
CTD PMID:22532600 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
N-hydroxy-PhIP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [ABCB1A protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions ISO [ABCB1B protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [ABCC3 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
multiple interactions
ISO ABCG2 protein affects the transport of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCG2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:18322075 PMID:30701287 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [CYP1A1 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:16167840 PMID:17052995 PMID:17279779 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine metabolite
[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:1943715 PMID:16167840 PMID:17279779 PMID:20192249 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:17279779 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO [CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:17279779 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases activity
ISO 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased activity of ESR1 protein
CTD PMID:16533016 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA1 protein CTD PMID:17122891 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA3 protein CTD PMID:17122891 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA4 protein CTD PMID:17122891 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTM1 protein CTD PMID:17122891 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases response to substance
ISO
EXP
[GSTP1 protein co-treated with Glutathione] inhibits the reaction [[Adenosine Triphosphate results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct]; [GSTP1 protein co-treated with Glutathione] inhibits the reaction [Adenosine Triphosphate results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTP1 protein
GSTP1 protein results in decreased susceptibility to 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:11196146 PMID:17122891 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
increases metabolic processing
ISO NAT1 protein affects the acetylation of and affects the activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
NAT1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:11505221 PMID:29596660 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions
increases metabolic processing
increases acetylation
EXP
ISO
4-biphenylamine inhibits the reaction [NAT2 protein results in increased acetylation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
NAT2 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:12222688 PMID:18842621 PMID:29596660 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression
multiple interactions
EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of PDIA3 protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of PDIA3 protein
CTD PMID:19639176 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Rab7a RAB7A, member RAS oncogene family affects expression
multiple interactions
EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of RAB7A protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of RAB7A protein
CTD PMID:19639176 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rps7 ribosomal protein S7 multiple interactions
affects expression
EXP [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of RPS7 protein
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of RPS7 protein
CTD PMID:19639176 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Sar1a secretion associated, Ras related GTPase 1A affects expression
multiple interactions
EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of SAR1A protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of SAR1A protein
CTD PMID:19639176 NCBI chr20:29,623,529...29,635,935
Ensembl chr20:29,623,553...29,635,935
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases metabolic processing
ISO SULT1A1 protein results in increased metabolism of and results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
SULT1A1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:12067565 PMID:29596660 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tp53 tumor protein p53 increases mutagenesis ISO 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of TP53 protein CTD PMID:33189884 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
affects metabolic processing
increases metabolic processing
increases glucuronidation
ISO UGT1A1 promoter polymorphism affects the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]; UGT1A1 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]; UGT1A1 protein results in increased glucuronidation of and results in decreased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 promoter polymorphism affects the metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:11442279 PMID:15310245 PMID:15769885 PMID:15986396 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:15310245 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases metabolic processing
multiple interactions
increases glucuronidation
ISO UGT1A4 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A4 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]
UGT1A4 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:15310245 PMID:15986396 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions
increases metabolic processing
increases glucuronidation
ISO UGT1A9 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]
UGT1A9 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A9 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:11375903 PMID:15310245 PMID:15986396 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
PD123319 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP PD 123319 inhibits the reaction [diminazene aceturate results in increased expression of ACE2 protein] CTD PMID:28688122 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Agt angiotensinogen multiple interactions
decreases activity
decreases response to substance
ISO
EXP
[olmesartan co-treated with PD 123319] inhibits the reaction [AGT protein modified form results in increased abundance of Fatty Acids, Nonesterified]; [olmesartan co-treated with PD 123319] inhibits the reaction [AGT protein modified form results in increased secretion of and results in increased abundance of Triglycerides]; PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 protein]
PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 protein]; PD 123319 inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; PD 123319 inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]]
PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]]; PD 123319 inhibits the reaction [AGT protein results in increased abundance of Nitric Oxide]; PD 123319 inhibits the reaction [AGT protein results in increased expression of ANGPT1 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of ANGPT2 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of EDN1 protein]; PD 123319 inhibits the reaction [AGT protein results in increased expression of KDR mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of MAP2 protein]; PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 protein]; PD 123319 inhibits the reaction [AGT protein results in increased expression of TEK mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of TUBB3 protein]; PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 protein]; PD 123319 inhibits the reaction [AGT protein results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of VEGFA protein]; PD 123319 promotes the reaction [AGT protein results in increased abundance of Prostaglandins E]
PD 123319 results in decreased activity of AGT protein modified form
PD 123319 results in decreased susceptibility to AGT protein
CTD PMID:9176287 PMID:9519251 PMID:11115077 PMID:14597853 PMID:14638905 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
decreases activity
increases expression
decreases expression
ISO
EXP
[PD 123319 binds to and results in decreased activity of AGTR2 protein] inhibits the reaction [candesartan results in increased expression of NOS3 protein]; PD 123319 binds to and results in decreased activity of AGTR2 protein
PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]]
PD 123319 results in decreased activity of AGTR2 protein
PD 123319 results in increased expression of AGTR2 mRNA; PD 123319 results in increased expression of AGTR2 protein
[PD 123319 binds to and results in decreased activity of AGTR2 protein] which affects the susceptibility to Phenylephrine; [PD 123319 results in decreased activity of AGTR2 protein] inhibits the reaction [Valsartan results in increased abundance of Cyclic GMP]; [PD 123319 results in decreased activity of AGTR2 protein] which results in decreased susceptibility to Estradiol; [PD 123319 results in decreased activity of AGTR2 protein] which results in decreased susceptibility to Valsartan; PD 123319 binds to and results in decreased activity of AGTR2 protein
PD 123319 results in decreased expression of AGTR2 mRNA
CTD PMID:9336375 PMID:9740612 PMID:11509473 PMID:11893553 PMID:15807884 More... NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Agtrap angiotensin II receptor-associated protein multiple interactions ISO PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]] CTD PMID:25446015 NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
JBrowse link
G Angpt1 angiopoietin 1 multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of ANGPT1 mRNA] CTD PMID:14638905 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Angpt2 angiopoietin 2 multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of ANGPT2 mRNA] CTD PMID:14638905 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO PD 123319 affects the reaction [BDKRB2 affects the abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:16514058 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA] CTD PMID:15284299 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP PD 123319 inhibits the reaction [Ethylene Glycol results in increased expression of CCL5 protein] CTD PMID:16284884 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]] CTD PMID:25446015 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of EDN1 protein] CTD PMID:15007106 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO PD123319 co-treated with losartan inhibits the reaction [Angiotensin II increases phosphorylation of JAK2 protein in liver] RGD PMID:22613986 RGD:127285667 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kdr kinase insert domain receptor multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of KDR mRNA] CTD PMID:14638905 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kng2 kininogen 2 multiple interactions EXP
ISO
PD 123319 inhibits the reaction [benazepril promotes the reaction [Valsartan results in increased expression of KNG1 protein modified form]]; PD 123319 inhibits the reaction [Valsartan promotes the reaction [benazepril results in increased expression of KNG1 protein modified form]]
PD 123319 affects the reaction [KNG1 affects the abundance of Nitric Oxide]
CTD PMID:11509473 PMID:16514058 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of MAP2 protein] CTD PMID:17068200 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO PD 123319 inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:19041135 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO PD 123319 inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:19041135 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 protein] CTD PMID:18206046 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 multiple interactions EXP PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] CTD PMID:17068200 NCBI chr16:51,202,497...51,347,791
Ensembl chr16:51,253,562...51,347,793
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP PD 123319 inhibits the reaction [Ethylene Glycol results in increased expression of NFKB1 protein] CTD PMID:16284884 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO [PD 123319 binds to and results in decreased activity of AGTR2 protein] inhibits the reaction [candesartan results in increased expression of NOS3 protein] CTD PMID:18551021 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]] CTD PMID:25446015 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]] CTD PMID:25446015 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP PD 123319 results in increased expression of PRKCE protein CTD PMID:11893553 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 multiple interactions EXP PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] CTD PMID:17068200 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 protein] CTD PMID:11115077 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of TEK mRNA] CTD PMID:14638905 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of TUBB3 protein] CTD PMID:17068200 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 multiple interactions ISO
EXP
PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 protein] CTD PMID:16769992 PMID:17068200 NCBI chr11:85,304,528...85,338,430
Ensembl chr11:85,304,526...85,336,369
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP PD 123319 inhibits the reaction [AGT protein results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [AGT protein results in increased expression of VEGFA protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] CTD PMID:14638905 PMID:14718351 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
PhIP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of A2M mRNA CTD PMID:15059925 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Aadat aminoadipate aminotransferase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of AADAT mRNA CTD PMID:33945839 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects transport
affects metabolic processing
multiple interactions
ISO ABCB1A protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCB1A protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCB1A protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCB1A protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
CTD PMID:18322075 PMID:30701287 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects metabolic processing
multiple interactions
ISO ABCB1B protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCB1B protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCB1B protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
CTD PMID:30701287 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ABCC1 mRNA CTD PMID:18680760 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases transport
affects metabolic processing
multiple interactions
affects transport
increases expression
ISO
EXP
ABCC2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCC2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
ABCC2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[Cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ABCC2 mRNA
CTD PMID:11306678 PMID:15057744 PMID:16356829 PMID:16611851 PMID:18680760 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects metabolic processing
multiple interactions
ISO ABCC3 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCC3 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCC3 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
CTD PMID:30701287 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression
multiple interactions
affects metabolic processing
decreases transport
increases expression
increases transport
affects transport
increases secretion
affects abundance
affects response to substance
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ABCG2 protein
[ABCG2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCG2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
ABCG2 gene polymorphism results in decreased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; ABCG2 protein results in decreased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ABCG2 mRNA
ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCG2 protein results in increased secretion of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; Beclomethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Cadmium Chloride inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Dexamethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Estradiol inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Methylprednisolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Triamcinolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
ABCG2 protein affects the abundance of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCG2 results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
ABCG2 affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:14559835 PMID:15365089 PMID:15722455 PMID:18322075 PMID:18680760 More... NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACAA1A mRNA CTD PMID:33945839 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acad8 acyl-CoA dehydrogenase family, member 8 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACAD8 mRNA CTD PMID:33945839 NCBI chr 8:25,382,271...25,406,429
Ensembl chr 8:25,382,273...25,406,414
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACADM mRNA CTD PMID:33945839 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acads acyl-CoA dehydrogenase short chain decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACADS mRNA CTD PMID:33945839 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACMSD mRNA CTD PMID:33945839 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsf3 acyl-CoA synthetase family member 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACSF3 mRNA CTD PMID:33945839 NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACTA1 mRNA CTD PMID:29877212 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACTA2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACTA2 mRNA
CTD PMID:15059925 PMID:15215175 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACTB mRNA CTD PMID:15215175 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg1 actin, gamma 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACTG1 mRNA CTD PMID:15215175 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ACTG2 mRNA CTD PMID:15059925 PMID:29877212 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Actn4 actinin alpha 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ACTN4 mRNA CTD PMID:12376462 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Adcy5 adenylate cyclase 5 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ADCY5 mRNA CTD PMID:12376462 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adss1 adenylosuccinate synthase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ADSSL1 mRNA CTD PMID:15215175 NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects response to substance
ISO [3'-methoxy-4'-nitroflavone results in decreased activity of AHR protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; AHR mutant form inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; AHR mutant form inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]
AHR protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:20816883 PMID:23208499 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor affects response to substance ISO AHRR protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:23208499 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of AKAP12 mRNA CTD PMID:20816883 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Alb albumin affects binding
increases expression
decreases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to ALB protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ALB mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALB mRNA
CTD PMID:8921513 PMID:15215175 PMID:27028147 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ALDH1A3 mRNA CTD PMID:33945839 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH1B1 mRNA CTD PMID:33945839 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH2 mRNA CTD PMID:33945839 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ALDH3A1 mRNA CTD PMID:20816883 PMID:33945839 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH3A2 mRNA CTD PMID:33945839 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH3B1 mRNA CTD PMID:33945839 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH6A1 mRNA CTD PMID:33945839 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ALDH7A1 mRNA CTD PMID:33945839 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALDH9A1 mRNA CTD PMID:33945839 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ALDOA mRNA CTD PMID:15215175 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ALOX5 mRNA CTD PMID:20816883 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amelx amelogenin, X-linked increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of AMELX mRNA CTD PMID:15215175 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions
increases methylation
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased methylation of ANGPTL4 promoter] which results in decreased expression of ANGPTL4 mRNA; [decitabine co-treated with trichostatin A] inhibits the reaction [[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased methylation of ANGPTL4 promoter] which results in decreased expression of ANGPTL4 mRNA] CTD PMID:21489049 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anxa1 annexin A1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ANXA1 mRNA CTD PMID:12376462 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Aoc1 amine oxidase, copper containing 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of AOC1 mRNA CTD PMID:33945839 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Aoc3 amine oxidase, copper containing 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of AOC3 mRNA CTD PMID:33945839 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of APAF1 mRNA CTD PMID:20816883 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apc APC regulator of WNT signaling pathway increases mutagenesis
multiple interactions
affects response to substance
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of APC gene
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of APC; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of APC gene
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased mutagenesis of APC gene
APC protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:7846077 PMID:8608549 PMID:9163695 PMID:9202738 PMID:11181456 More... NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apoc2 apolipoprotein C2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of APOC2 mRNA CTD PMID:15215175 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G App amyloid beta precursor protein increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of APP protein; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of APP protein modified form CTD PMID:32169473 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aprt adenine phosphoribosyl transferase multiple interactions ISO [CYP1A2 protein co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased mutagenesis of APRT gene CTD PMID:2023932 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of AQP1 mRNA CTD PMID:12376462 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ARHGEF1 mRNA CTD PMID:15215175 NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ARHGEF3 mRNA CTD PMID:15215175 NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ASCL2 mRNA CTD PMID:15059925 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATF4 mRNA CTD PMID:20702593 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATF7IP mRNA CTD PMID:20816883 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
JBrowse link
G Atl1 atlastin GTPase 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATL1 mRNA CTD PMID:20816883 NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATP2A1 mRNA CTD PMID:15215175 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATP5F1B mRNA CTD PMID:15215175 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATPIF1 mRNA CTD PMID:12376462 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATP5MC1 mRNA CTD PMID:15215175 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATP5MC3 mRNA CTD PMID:15215175 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATP5PB mRNA CTD PMID:15215175 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
affects expression
ISO myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of ATR mRNA] CTD PMID:32342131 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of AUH mRNA CTD PMID:33945839 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 increases mutagenesis ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of B4GALNT2 CTD PMID:9202738 NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700
JBrowse link
G Bace1 beta-secretase 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BACE1 protein CTD PMID:32169473 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BAG1 mRNA CTD PMID:15215175 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BASP1 mRNA CTD PMID:12376462 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BAX mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BAX protein
Hexachlorocyclohexane promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BAX protein]
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in decreased expression of BAX protein
CTD PMID:11751460 PMID:16120219 PMID:18174961 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of BCAS3 mRNA CTD PMID:22100608 NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased expression of BCL2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BCL2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BCL2 protein
CTD PMID:11751460 PMID:18174961 PMID:23810796 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of BNC2 mRNA CTD PMID:20816883 NCBI chr 5:98,679,071...99,079,742
Ensembl chr 5:98,687,410...99,079,426
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of BRCA1 protein CTD PMID:12203372 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Btf3 basic transcription factor 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BTF3 mRNA CTD PMID:15215175 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BTN1A1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of BTN1A1 mRNA
CTD PMID:15215175 NCBI chr17:41,654,237...41,663,427
Ensembl chr17:41,654,249...41,664,272
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Bysl bystin-like increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BYSL mRNA CTD PMID:15215175 NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339
JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BZW2 mRNA CTD PMID:15215175 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of C1QTNF3 mRNA CTD PMID:20816883 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G Cab39l calcium binding protein 39-like decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CAB39L mRNA CTD PMID:20816883 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CACNA2D1 mRNA CTD PMID:15059925 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Capg capping actin protein, gelsolin like decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CAPG mRNA CTD PMID:15215175 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CAPRIN1 mRNA CTD PMID:15215175 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CA2 mRNA CTD PMID:15215175 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car4 carbonic anhydrase 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CAR4 mRNA CTD PMID:15059925 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CASK mRNA CTD PMID:12376462 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased activity of CASP3 protein
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of CASP3 protein
CTD PMID:18616682 PMID:20307560 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CASP8 mRNA CTD PMID:20816883 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase increases activity
decreases expression
multiple interactions
EXP
ISO
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of CAT protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CAT mRNA
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Buprenorphine] results in increased activity of CAT protein
CTD PMID:23313794 PMID:32113805 PMID:33945839 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCL20 mRNA CTD PMID:15059925 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccna2 cyclin A2 increases expression
decreases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNA2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNA2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CCNA2 protein
CTD PMID:10728688 PMID:16120219 PMID:29877212 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNB1 protein CTD PMID:16120219 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNB2 mRNA CTD PMID:29877212 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression
increases expression
multiple interactions
ISO
IEP
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCND1 protein
PhIP increases expression of Ccnd1 mRNA and protein in rat mammary gland
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of CCND1 mRNA; Plant Preparations inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCND1 mRNA]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCND1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCND1 protein
CTD
RGD
PMID:12097258 PMID:12376462 PMID:14522882 PMID:18283038 PMID:21081470 More... RGD:2292404 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCND2 mRNA CTD PMID:15059925 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnh cyclin H increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNH mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNH protein CTD PMID:12606953 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCT2 mRNA CTD PMID:15215175 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCT4 mRNA CTD PMID:15215175 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCT5 mRNA CTD PMID:15215175 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCT7 mRNA CTD PMID:15215175 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCT8 mRNA CTD PMID:15215175 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
JBrowse link
G Cd24 CD24 molecule increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CD24A mRNA CTD PMID:15215175 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd27 CD27 molecule increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CD27 mRNA CTD PMID:20816883 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd74 CD74 molecule decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CD74 mRNA CTD PMID:15215175 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd81 Cd81 molecule increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CD81 mRNA CTD PMID:15215175 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDC25C mRNA CTD PMID:16120219 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDC34 mRNA CTD PMID:16120219 NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDC45 mRNA CTD PMID:16120219 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDCA3 mRNA CTD PMID:29877212 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDH1 protein] CTD PMID:22307971 PMID:22581815 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh26 cadherin 26 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDH26 mRNA CTD PMID:20816883 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
increases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDK1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK1 mRNA
CTD PMID:20816883 PMID:29877212 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk13 cyclin-dependent kinase 13 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK13 mRNA CTD PMID:20816883 NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721
JBrowse link
G Cdk2ap1 cyclin-dependent kinase 2 associated protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK2AP1 mRNA CTD PMID:15215175 NCBI chr12:32,249,783...32,258,483
Ensembl chr12:32,249,747...32,258,479
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK4 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK4 protein CTD PMID:12376462 PMID:14522882 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDK9 mRNA CTD PMID:20816883 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDKN1A mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDKN1A protein CTD PMID:11425520 PMID:15635149 PMID:17156947 PMID:23810796 PMID:29877212 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDKN2A mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CDKN2A protein CTD PMID:23313794 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects response to substance
increases phosphorylation
ISO CEBPB protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of CEBPB protein
CTD PMID:23208499 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cenpf centromere protein F increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CENPF mRNA CTD PMID:16120219 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CEP290 mRNA CTD PMID:20816883 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Cfhr4 complement factor H-related 4 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CFHR4 mRNA CTD PMID:20816883 NCBI chr13:51,422,592...51,491,476
Ensembl chr13:51,422,592...51,491,502
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CHAC2 mRNA CTD PMID:33945839 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
JBrowse link
G Chat choline O-acetyltransferase increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CHAT mRNA CTD PMID:20816883 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of CHEK1 protein CTD PMID:32466334 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of CHEK2 protein CTD PMID:32466334 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CHRNB2 mRNA CTD PMID:15215175 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CKAP2 mRNA CTD PMID:29877212 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckm creatine kinase, M-type increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CKM mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CKM mRNA
CTD PMID:15059925 PMID:15215175 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CKS2 mRNA CTD PMID:29877212 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn14 claudin 14 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CLDN14 mRNA CTD PMID:20816883 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Cldn3 claudin 3 multiple interactions EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of CLDN3 mRNA CTD PMID:12097258 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Clk2 CDC-like kinase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CLK2 mRNA CTD PMID:15215175 NCBI chr 2:174,570,614...174,582,645
Ensembl chr 2:174,570,653...174,588,985
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CNBP mRNA CTD PMID:15215175 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cndp1 carnosine dipeptidase 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CNDP1 mRNA CTD PMID:33945839 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765
JBrowse link
G Cnn1 calponin 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CNN1 mRNA CTD PMID:15215175 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Cnn3 calponin 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CNN3 mRNA CTD PMID:12376462 NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COL12A1 mRNA CTD PMID:15215175 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COL1A1 mRNA CTD PMID:15215175 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COL1A2 mRNA CTD PMID:15215175 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col2a1 collagen type II alpha 1 chain increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COL2A1 mRNA CTD PMID:15215175 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of COL5A1 mRNA CTD PMID:12376462 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Comt catechol-O-methyltransferase affects response to substance EXP COMT protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:12901791 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coro1a coronin 1A increases methylation
multiple interactions
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased methylation of CORO1A promoter
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased methylation of CORO1A promoter] which results in decreased expression of CORO1A mRNA
CTD PMID:21489049 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COX6C mRNA CTD PMID:15215175 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COX7A2 mRNA CTD PMID:15215175 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COX7C mRNA CTD PMID:15215175 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CRYAB mRNA CTD PMID:15059925 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csn1s1 casein alpha s1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CSN1S1 mRNA CTD PMID:15215175 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614
JBrowse link
G Csn2 casein beta multiple interactions
increases expression
decreases expression
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] affects the expression of CSN2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CSN2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CSN2 mRNA
CTD PMID:9879772 PMID:15215175 NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817
JBrowse link
G Csn3 casein kappa decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CSN3 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CSN3 mRNA
CTD PMID:15215175 NCBI chr14:20,154,032...20,160,585
Ensembl chr14:20,154,032...20,160,587
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
increases mutagenesis
ISO
EXP
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of CTNNB1 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased mutagenesis of CTNNB1 gene; CTNNB1 gene mutant form results in increased susceptibility to [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate]
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] affects the localization of CTNNB1 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of CTNNB1 mRNA; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of CTNNB1 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased mutagenesis of CTNNB1 gene; Plant Preparations inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CTNNB1 mRNA]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CTNNB1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CTNNB1 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of CTNNB1 gene
CTD PMID:9515794 PMID:10965019 PMID:11756241 PMID:14507667 PMID:15459021 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
EXP
ISO
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of CTSD mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CTSD protein
CTD PMID:12097258 PMID:20951759 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CXCL10 mRNA CTD PMID:15059925 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CXCR3 mRNA CTD PMID:20816883 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Ethanol] results in increased activity of CYP19A1 protein CTD PMID:32113805 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression
affects metabolic processing
increases expression
multiple interactions
increases hydroxylation
increases metabolic processing
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of CYP1A1 protein; CYP1A1 results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CYP1A1 mRNA
CYP1A1 gene SNP affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA
CYP1A1 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 protein]
CYP1A1 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[CYP1A1 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP1A1 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased expression of CYP1A1 mRNA; [[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [Benzo(a)pyrene co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased expression of CYP1A1 mRNA; [CYP1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; AHR mutant form inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]; xanthohumol promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A1 mRNA]
CTD PMID:1913651 PMID:2334931 PMID:8902619 PMID:15598703 PMID:16167840 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation
affects metabolic processing
increases expression
multiple interactions
affects oxidation
increases activity
increases response to substance
increases metabolic processing
affects response to substance
increases oxidation
ISO
EXP
CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 gene SNP affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA
[1-Naphthylisothiocyanate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in decreased expression of CYP1A2 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 1-Naphthylisothiocyanate] results in decreased expression of CYP1A2 protein; Caffeine promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]
CYP1A2 affects the oxidation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein
CYP1A2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 protein results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[CYP1A2 protein co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased mutagenesis of APRT gene; [CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 protein polymorphism results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CYP1A2 results in increased oxidation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [CYP1A2 protein results in decreased ethylation of Phenacetin]; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with CYP1A2 protein] results in increased mutagenesis of HPRT1 gene; [[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine metabolite; AHR mutant form inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]; CYP1A2 protein results in increased hydroxylation of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased hydroxylation of and results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; CYP1A2 protein results in increased oxidation of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; furafylline inhibits the reaction [CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
CTD PMID:1913651 PMID:1943715 PMID:2023932 PMID:2334931 PMID:8020169 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression
increases metabolic processing
increases activity
increases expression
ISO
EXP
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1B1 mRNA; [CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1B1 mRNA]; IL6 protein promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1B1 mRNA]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CYP1B1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of CYP1B1 protein
CTD PMID:17279779 PMID:20307560 PMID:20702593 PMID:20816883 PMID:29362861 More... NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CYP27B1 mRNA CTD PMID:20816883 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2B2 protein CTD PMID:15598703 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases metabolic processing
multiple interactions
ISO CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine; [CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:17279779 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
multiple interactions
ISO CYP2D6 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[CYP2D6 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine
CTD PMID:17279779 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2E1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; 5,15-diphenylporphyrin inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2E1 mRNA]; Ethanol promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2E1 mRNA]; fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2E1 mRNA]
CTD PMID:29362861 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP
ISO
CYP3A4 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP3A4 mRNA
CTD PMID:1913651 PMID:29549414 PMID:31542801 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dab2 DAB adaptor protein 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DAB2 mRNA CTD PMID:15215175 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dag1 dystroglycan 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DAG1 mRNA CTD PMID:15215175 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DAPK3 mRNA CTD PMID:15215175 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Dbi diazepam binding inhibitor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DBI mRNA CTD PMID:12376462 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dcaf1 DDB1 and CUL4 associated factor 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DCAF1 mRNA CTD PMID:20816883 NCBI chr 8:107,466,229...107,540,633
Ensembl chr 8:107,474,312...107,540,627
JBrowse link
G Dcn decorin increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DCN mRNA CTD PMID:15215175 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddc dopa decarboxylase decreases activity
decreases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased activity of DDC protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DDC mRNA
CTD PMID:2243617 PMID:33945839 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Defal1 defensin alpha-like 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DEFAL1 mRNA CTD PMID:15059925 NCBI chr16:70,371,518...70,372,353
Ensembl chr16:70,371,518...70,372,353
JBrowse link
G Des desmin decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DES mRNA CTD PMID:12376462 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DHRS2 mRNA CTD PMID:20816883 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DHX15 mRNA CTD PMID:15215175 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Diaph3 diaphanous-related formin 3 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DIAPH3 mRNA CTD PMID:20816883 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dido1 death inducer-obliterator 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DIDO1 mRNA CTD PMID:20816883 NCBI chr 3:167,772,535...167,825,894
Ensembl chr 3:167,772,770...167,817,218
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DLG4 protein CTD PMID:32169473 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DMBT1 mRNA CTD PMID:15059925 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DNAH11 mRNA CTD PMID:15215175 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536
JBrowse link
G Dnajb8 DnaJ heat shock protein family (Hsp40) member B8 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DNAJB8 mRNA CTD PMID:20816883 NCBI chr 4:120,681,918...120,685,108
Ensembl chr 4:120,681,926...120,687,552
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression
multiple interactions
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of DNMT1 protein
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA
CTD PMID:12097258 PMID:22581815 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DPYD mRNA CTD PMID:33945839 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Edn1 endothelin 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EDN1 mRNA CTD PMID:15215175 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EEF1A1 mRNA CTD PMID:12376462 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of EFEMP1 mRNA CTD PMID:12376462 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Egf epidermal growth factor decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of EGF mRNA CTD PMID:20816883 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EGFR mRNA CTD PMID:8603490 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EGR1 mRNA CTD PMID:20816883 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehf ets homologous factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EHF mRNA CTD PMID:15215175 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EIF5A mRNA CTD PMID:15215175 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Eno1 enolase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ENO1 mRNA CTD PMID:12376462 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of EPHX1 mRNA CTD PMID:12376462 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eps8l3 EPS8 like 3 affects response to substance ISO EPS8L3 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:19223546 Ensembl chr 2:195,514,692...195,528,085 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ERBB2 mRNA CTD PMID:8603490 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ERCC1 mRNA CTD PMID:22100608 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Erh ERH, mRNA splicing and mitosis factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ERH mRNA CTD PMID:15215175 NCBI chr 6:100,280,930...100,291,449
Ensembl chr 6:100,280,930...100,291,210
JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ERP44 mRNA CTD PMID:15215175 NCBI chr 5:62,516,550...62,610,762
Ensembl chr 5:62,516,551...62,610,761
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects response to substance
increases expression
increases activity
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to and results in increased activity of ESR1 protein; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; [fulvestrant results in decreased expression of ESR1 protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; Estradiol inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to ESR1 protein]; fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of ESR1 protein]
ESR1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR1 protein
CTD PMID:15319301 PMID:15637090 PMID:16533016 PMID:23208499 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR2 protein CTD PMID:15637090 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ezr ezrin increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EZR mRNA CTD PMID:12376462 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of F2R mRNA CTD PMID:20816883 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of FHIT mRNA CTD PMID:22100608 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fn1 fibronectin 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of FN1 mRNA CTD PMID:12376462 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fnbp1l formin binding protein 1-like increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of FNBP1L mRNA CTD PMID:20816883 NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP
ISO
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of FOS mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of FOS protein CTD PMID:20816883 PMID:23313794 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of FURIN mRNA CTD PMID:12376462 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of G0S2 mRNA CTD PMID:15215175 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gab1 GRB2-associated binding protein 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GAB1 mRNA CTD PMID:20816883 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GADD45A mRNA CTD PMID:23810796 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gap43 growth associated protein 43 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GAP43 mRNA CTD PMID:15059925 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GCDH mRNA CTD PMID:33945839 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gda guanine deaminase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GDA mRNA CTD PMID:12376462 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Ggct gamma-glutamyl cyclotransferase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GGCT mRNA CTD PMID:33945839 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GGT1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GGT1 mRNA
CTD PMID:12376462 PMID:33945839 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ggt7 gamma-glutamyltransferase 7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GGT7 mRNA CTD PMID:33945839 NCBI chr 3:143,978,073...144,004,597
Ensembl chr 3:143,978,082...144,001,492
JBrowse link
G Glul glutamate-ammonia ligase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GLUL mRNA CTD PMID:15215175 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gna13 G protein subunit alpha 13 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GNA13 mRNA CTD PMID:20816883 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GNAI2 mRNA CTD PMID:15215175 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GNAT1 mRNA CTD PMID:20816883 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GNMT mRNA CTD PMID:22100608 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Golga4 golgin A4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GOLGA4 mRNA CTD PMID:15215175 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Gpc3 glypican 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GPC3 mRNA CTD PMID:15215175 NCBI chr  X:131,868,983...132,236,837
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpr135 G protein-coupled receptor 135 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GPR135 mRNA CTD PMID:20816883 NCBI chr 6:90,627,533...90,636,311
Ensembl chr 6:90,629,178...90,630,551
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX1 mRNA CTD PMID:33945839 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX2 protein CTD PMID:18056462 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX3 mRNA CTD PMID:33945839 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX4 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GPX4 mRNA
CTD PMID:15215175 PMID:33945839 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX7 mRNA CTD PMID:33945839 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
JBrowse link
G Gpx8 glutathione peroxidase 8 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GPX8 mRNA CTD PMID:33945839 NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195
JBrowse link
G Grm3 glutamate metabotropic receptor 3 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GRM3 mRNA CTD PMID:20816883 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Grm4 glutamate metabotropic receptor 4 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GRM4 mRNA CTD PMID:20816883 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Gspt1 G1 to S phase transition 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSPT1 mRNA CTD PMID:15215175 NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSR mRNA CTD PMID:33945839 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSS mRNA CTD PMID:12376462 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects response to substance
multiple interactions
decreases expression
ISO GSTA1 gene polymorphism affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[xanthohumol co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased expression of GSTA1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTA1 mRNA
CTD PMID:14601045 PMID:22138251 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTA3 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA3 mRNA
CTD PMID:15215175 PMID:33945839 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTA4 mRNA CTD PMID:33945839 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA6 mRNA CTD PMID:33945839 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTK1 mRNA CTD PMID:33945839 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:22564066 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTM2 mRNA CTD PMID:33945839 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTM4 mRNA CTD PMID:33945839 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm6 glutathione S-transferase, mu 6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTM5 mRNA CTD PMID:15059925 NCBI chr 2:195,579,566...195,584,340
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTO1 mRNA CTD PMID:33945839 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases expression
affects response to substance
EXP
ISO
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of GSTP1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTP1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GSTP1 protein
GSTP1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:12097258 PMID:19223546 PMID:22581815 PMID:33945839 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 gene polymorphism affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:22564066 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GUCY1A1 mRNA CTD PMID:15059925 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G H2ax H2A.X variant histone increases expression
increases phosphorylation
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of H2AX protein modified form
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of H2AX protein
CTD PMID:28160022 PMID:32466334 PMID:34510228 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H3f3b H3.3 histone B increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of H3F3B mRNA CTD PMID:15215175 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G H3f4 H3.4 histone decreases methylation
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased methylation of H3-4 protein
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 4-biphenylamine co-treated with Benzo(a)pyrene co-treated with Tetrachlorodibenzodioxin] results in decreased methylation of H3-4 protein
CTD PMID:17468514 NCBI chr10:43,740,797...43,741,207 JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HAAO mRNA CTD PMID:33945839 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HADH mRNA CTD PMID:33945839 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HADHB mRNA CTD PMID:33945839 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HBA1 mRNA CTD PMID:12376462 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions
decreases expression
affects response to substance
ISO
EXP
kaempferol inhibits the reaction [HBB gene polymorphism results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Quercetin inhibits the reaction [HBB gene polymorphism results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HBB mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HBB-B1 mRNA
HBB protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
CTD PMID:14691983 PMID:15215175 PMID:29877212 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hccs holocytochrome c synthase decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HCCS mRNA CTD PMID:20816883 NCBI chr  X:24,932,943...24,942,376
Ensembl chr  X:24,933,002...24,942,366
JBrowse link
G Hemk1 HemK methyltransferase family member 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HEMK1 mRNA CTD PMID:20816883 NCBI chr 8:107,999,658...108,010,732
Ensembl chr 8:107,999,644...108,010,256
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HIBCH mRNA CTD PMID:33945839 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HIF1A protein CTD PMID:22307971 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMGB2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMGB2 protein CTD PMID:29877212 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMGCLL1 mRNA CTD PMID:33945839 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HMGCS2 mRNA CTD PMID:15059925 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMGN1 mRNA CTD PMID:15215175 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMGN2 mRNA CTD PMID:15215175 NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of HMOX1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HMOX1 mRNA
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA
CTD PMID:12097258 PMID:20307560 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1b HNF1 homeobox B decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HNF1B mRNA CTD PMID:20816883 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis
multiple interactions
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 intron
Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]; beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]; Vitamin E inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with CYP1A2 protein] results in increased mutagenesis of HPRT1 gene; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct] which results in increased mutagenesis of HPRT1 gene; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased mutagenesis of HPRT1 gene; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 intron] which affects the splicing of HPRT1 mRNA
CTD PMID:7728948 PMID:8625468 PMID:10728688 PMID:10987307 PMID:11289141 More... NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression
increases mutagenesis
multiple interactions
affects response to substance
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HRAS mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HRAS protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HRAS gene
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of and results in increased activity of HRAS; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct] which results in increased mutagenesis of HRAS gene; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HRAS gene] which results in increased activity of HRAS protein; Dietary Fats affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HRAS gene]
HRAS protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of Reactive Oxygen Species]; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOX1 protein]; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK3 protein]
CTD PMID:8039140 PMID:9433479 PMID:11165753 PMID:12507937 PMID:15132766 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSD17B10 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HSD17B10 mRNA
CTD PMID:15215175 PMID:33945839 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSP90AA1 mRNA CTD PMID:15215175 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSP90AB1 mRNA CTD PMID:15215175 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPA1A mRNA CTD PMID:29877212
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HSPA2 mRNA CTD PMID:15059925 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPA5 mRNA CTD PMID:15215175 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPA8 mRNA CTD PMID:15215175 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of HSPB1 mRNA CTD PMID:15059925 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of HSPD1 mRNA; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of HSPD1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPD1 mRNA
CTD PMID:12097258 PMID:15215175 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions
increases expression
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of HSPE1 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPE1 mRNA
CTD PMID:12097258 PMID:15215175 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HSPH1 mRNA CTD PMID:15215175 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of ICAM1 mRNA CTD PMID:12097258 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ID2 mRNA CTD PMID:15215175 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ID3 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ID3 mRNA
CTD PMID:12376462 PMID:15059925 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ID4 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ID4 protein CTD PMID:14633621 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IDH1 mRNA CTD PMID:33945839 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IDH2 mRNA CTD PMID:33945839 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IDO1 mRNA CTD PMID:33945839 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IFNAR2 mRNA CTD PMID:15215175 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124
JBrowse link
G Ifng interferon gamma increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IFNG mRNA CTD PMID:20702593 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IGFBP1 mRNA CTD PMID:15059925 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IGFBP2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IGFBP2 mRNA
CTD PMID:15215175 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IL1B mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IL1B mRNA
CTD PMID:15059925 PMID:20702593 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 decreases secretion
decreases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased secretion of IL2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IL2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]
CTD PMID:16168555 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IL4I1 mRNA CTD PMID:33945839 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IL6 mRNA
[IL6 protein co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in decreased expression of MIR27B mRNA; IL6 protein promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1B1 mRNA]
CTD PMID:20702593 PMID:31515600 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IL6ST mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IL6ST protein CTD PMID:12606953 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of IMPDH2 mRNA CTD PMID:15215175 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of INMT mRNA CTD PMID:33945839 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in decreased expression of BAX protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased activity of STAT5A protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased expression of BCL2 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased expression of STAT5A protein modified form CTD PMID:11751460 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of INSIG1 mRNA CTD PMID:12376462 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Itga7 integrin subunit alpha 7 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ITGA7 mRNA CTD PMID:15059925 NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of IVD mRNA CTD PMID:33945839 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of JAK2 mRNA CTD PMID:29362861 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of JUN mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of JUN protein
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of JUN mRNA
CTD PMID:18283038 PMID:23313794 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kat6b lysine acetyltransferase 6B increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KAT6B mRNA CTD PMID:20816883 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KCNK1 mRNA CTD PMID:15215175 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kctd2 potassium channel tetramerization domain containing 2 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KCTD2 mRNA CTD PMID:20816883 NCBI chr10:100,663,013...100,674,756
Ensembl chr10:100,662,884...100,674,336
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of and affects the localization of KDM1A protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 4-biphenylamine co-treated with Benzo(a)pyrene] affects the localization of KDM1A protein CTD PMID:17468514 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kif20a kinesin family member 20A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KIF20A mRNA CTD PMID:29877212 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Klf10 Kruppel-like factor 10 multiple interactions EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of KLF10 mRNA CTD PMID:12097258 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Kmo kynurenine 3-monooxygenase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KMO mRNA CTD PMID:33945839 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Krt19 keratin 19 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KRT19 mRNA CTD PMID:15215175 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt5 keratin 5 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KRT5 mRNA CTD PMID:12376462 NCBI chr 7:132,846,355...132,851,986
Ensembl chr 7:132,846,136...132,851,850
JBrowse link
G Kyat3 kynurenine aminotransferase 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of KYAT3 mRNA CTD PMID:33945839 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227
JBrowse link
G Kynu kynureninase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of KYNU mRNA CTD PMID:33945839 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LAPTM4B mRNA CTD PMID:15215175 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Lcn2 lipocalin 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LCN2 mRNA CTD PMID:15215175 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of LIN7A mRNA CTD PMID:12376462 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Lmo4 LIM domain only 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of LMO4 mRNA CTD PMID:15215175 NCBI chr 2:233,264,180...233,280,881
Ensembl chr 2:233,264,182...233,280,880
JBrowse link
G LOC100909569 zinc finger protein 91-like decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ZNF624 mRNA CTD PMID:20816883 NCBI chr 7:7,853,363...7,891,014
Ensembl chr 7:7,853,403...7,890,974
JBrowse link
G Loxl2 lysyl oxidase-like 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of LOXL2 mRNA CTD PMID:29877212 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Lpl lipoprotein lipase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of LPL mRNA CTD PMID:12376462 PMID:15059925 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LRP1 mRNA CTD PMID:15215175 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of LRRIQ3 mRNA CTD PMID:20816883 NCBI chr 2:244,119,975...244,214,590
Ensembl chr 2:244,126,200...244,212,339
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LSR mRNA CTD PMID:12376462 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LTBP3 mRNA CTD PMID:15215175 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Lum lumican increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of LUM mRNA CTD PMID:15215175 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MANF mRNA CTD PMID:15215175 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Maoa monoamine oxidase A decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MAOA mRNA CTD PMID:33945839 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MAOB mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAOB mRNA
CTD PMID:15059925 PMID:33945839 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAP2K1 protein CTD PMID:22307971 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases phosphorylation ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAP2K2 protein CTD PMID:22307971 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases expression
ISO fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPK1 protein modified form]; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK1 protein]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK1 protein]
CTD PMID:15319301 PMID:18056474 PMID:18845389 PMID:22307971 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of MAPK14 mRNA CTD PMID:20702593 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
increases expression
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK3 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK3 protein]
fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPK3 protein modified form]; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of MAPK3 protein]
CTD PMID:15319301 PMID:18056474 PMID:18845389 PMID:22307971 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPT protein modified form CTD PMID:32169473 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MAT2A mRNA CTD PMID:20816883 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Matr3 matrin 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MATR3 mRNA CTD PMID:15215175 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166
JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCCC1 mRNA CTD PMID:33945839 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222
JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MCEE mRNA CTD PMID:33945839 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM2 mRNA CTD PMID:16120219 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM6 mRNA CTD PMID:16120219 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM7 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM7 protein CTD PMID:16120219 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MCM8 mRNA CTD PMID:16120219 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MDH2 mRNA CTD PMID:12376462 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mdk midkine increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MDK mRNA CTD PMID:15215175 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MDM2 protein CTD PMID:15635149 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Melk maternal embryonic leucine zipper kinase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MELK mRNA CTD PMID:29877212 NCBI chr 5:58,540,393...58,600,937
Ensembl chr 5:58,540,449...58,600,937
JBrowse link
G Mep1a meprin A subunit alpha decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MEP1A mRNA CTD PMID:15059925 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MFGE8 mRNA CTD PMID:15215175 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MGMT mRNA CTD PMID:12706856 PMID:15215175 PMID:29877212 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgp matrix Gla protein increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MGP mRNA CTD PMID:12376462 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MGST1 mRNA CTD PMID:33945839 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MGST2 mRNA CTD PMID:33945839 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MGST3 mRNA CTD PMID:33945839 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mif macrophage migration inhibitory factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MIF mRNA CTD PMID:12376462 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir106b microRNA 106b decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR106B mRNA CTD PMID:24877718 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Mir141 microRNA 141 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR141 mRNA CTD PMID:24877718 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir200c microRNA 200c decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR200C mRNA CTD PMID:24877718 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir21 microRNA 21 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR21 mRNA CTD PMID:24877718 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir27b microRNA 27b multiple interactions ISO [IL6 protein co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in decreased expression of MIR27B mRNA CTD PMID:31515600 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir30d microRNA 30d decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR30D mRNA CTD PMID:24877718 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472
JBrowse link
G Mir330 microRNA 330 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR330 mRNA CTD PMID:24877718 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
JBrowse link
G Mir494 microRNA 494 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MIR494 mRNA CTD PMID:24877718 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir615 microRNA 615 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MIR615 mRNA CTD PMID:24877718 NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MKI67 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MKI67 protein
CTD PMID:23535288 PMID:29877212 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MKNK2 mRNA CTD PMID:15215175 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mlh1 mutL homolog 1 affects response to substance ISO MLH1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:11425520 PMID:16256150 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mlycd malonyl-CoA decarboxylase decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MLYCD mRNA CTD PMID:33945839 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MMP12 mRNA CTD PMID:15059925 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MMP2 protein] CTD PMID:22307971 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MMP7 mRNA CTD PMID:15059925 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases secretion
increases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased secretion of MMP9 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MMP9 protein
U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MMP9 protein]
CTD PMID:20951759 PMID:22307971 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Morc4 MORC family CW-type zinc finger 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MORC4 mRNA CTD PMID:29877212 NCBI chr  X:103,477,366...103,529,026
Ensembl chr  X:103,480,603...103,528,956
JBrowse link
G Msh2 mutS homolog 2 affects response to substance ISO
EXP
MSH2 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:11593414 PMID:12901791 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 affects response to substance
increases expression
ISO MSH6 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MSH6 protein
CTD PMID:11425520 PMID:26091049 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of COX1 mRNA CTD PMID:12376462 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CYTB mRNA CTD PMID:20816883 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt1 metallothionein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MT1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MT1A mRNA CTD PMID:15215175 PMID:29877212 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MT2A mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of MT2A mRNA
CTD PMID:15215175 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mutyh mutY DNA glycosylase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MUTYH mRNA CTD PMID:15215175 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
multiple interactions
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MYC protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MYC mRNA
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of MYC mRNA; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of MYC protein; [Dietary Fats co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased expression of MYC mRNA; Caffeine promotes the reaction [[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of MYC mRNA]; Plant Preparations promotes the reaction [[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of MYC mRNA]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MYC protein alternative form
CTD PMID:8603490 PMID:15059925 PMID:15319301 PMID:18283038 PMID:18616682 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh11 myosin heavy chain 11 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MYH11 mRNA CTD PMID:15215175 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
JBrowse link
G Myl6 myosin light chain 6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MYL6 mRNA CTD PMID:15215175 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
JBrowse link
G N4bp1 Nedd4 binding protein 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of N4BP1 mRNA CTD PMID:20816883 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570
JBrowse link
G Nat1 N-acetyltransferase 1 affects response to substance
increases expression
ISO NAT1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NAT1 mRNA
CTD PMID:18499698 PMID:31542801 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nat2 N-acetyltransferase 2 increases activity
increases expression
decreases expression
ISO NAT2 protein polymorphism results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; NAT2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NAT2 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of NAT2 mRNA
CTD PMID:15110095 PMID:22138251 PMID:29549414 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nat8f1 N-acetyltransferase 8 (GCN5-related) family member 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of NAT8F1 mRNA CTD PMID:33945839 NCBI chr 4:118,336,208...118,342,923
Ensembl chr 4:118,332,862...118,344,035
JBrowse link
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of NAT8F3 mRNA CTD PMID:33945839 NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500
JBrowse link
G Nav2 neuron navigator 2 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NAV2 mRNA CTD PMID:20816883 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
JBrowse link
G Ndn necdin, MAGE family member multiple interactions
increases methylation
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased methylation of NDN promoter] which results in decreased expression of NDN mRNA CTD PMID:21489049 NCBI chr 1:115,849,168...115,850,767
Ensembl chr 1:115,849,105...115,850,767
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of NDRG2 mRNA CTD PMID:15059925 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NDUFA2 mRNA CTD PMID:15215175 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NEK2 mRNA CTD PMID:16120219 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NFE2L2 mRNA
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased expression of NFE2L2 mRNA
CTD PMID:20307560 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of NFE2L3 mRNA CTD PMID:15215175 NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NFKB1 CTD PMID:20715105 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NKG7 mRNA CTD PMID:20816883 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Nme9 NME/NM23 family member 9 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NME9 mRNA CTD PMID:20816883 NCBI chr 8:100,013,190...100,034,511 JBrowse link
G Nnat neuronatin increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NNAT mRNA CTD PMID:15215175 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Nop10 NOP10 ribonucleoprotein increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOP10 mRNA CTD PMID:15215175 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of NOS2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOS2 protein
CTD PMID:15459021 PMID:21081470 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nox1 NADPH oxidase 1 increases expression
affects response to substance
multiple interactions
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOX1 protein
NOX1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[diphenyleneiodonium results in decreased activity of NOX1 protein] inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of Reactive Oxygen Species]; [diphenyleneiodonium results in decreased activity of NOX1 protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; HRAS protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOX1 protein]; NOX1 protein affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased abundance of Reactive Oxygen Species]; U 0126 inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOX1 protein]
CTD PMID:20715105 PMID:22307971 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nox4 NADPH oxidase 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NOX4 CTD PMID:20715105 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NPM1 mRNA CTD PMID:15215175 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NSMF mRNA CTD PMID:12376462 NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NTRK1 mRNA CTD PMID:20816883 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Numb NUMB, endocytic adaptor protein increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NUMB mRNA CTD PMID:15215175 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of NUSAP1 mRNA CTD PMID:29877212 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:9581821 PMID:10503888 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Odf4 outer dense fiber of sperm tails 4 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ODF4 mRNA CTD PMID:20816883 NCBI chr10:53,628,592...53,634,525
Ensembl chr10:53,628,759...53,634,359
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Osm oncostatin M increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of OSM mRNA CTD PMID:20816883 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of OXCT1 mRNA CTD PMID:33945839 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
JBrowse link
G Padi4 peptidyl arginine deiminase 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PADI4 mRNA CTD PMID:12376462 NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362
JBrowse link
G Papola poly (A) polymerase alpha increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PAPOLA mRNA CTD PMID:15215175 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Paqr7 progestin and adipoQ receptor family member 7 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PAQR7 mRNA CTD PMID:20816883 NCBI chr 5:146,709,085...146,720,577
Ensembl chr 5:146,708,900...146,720,673
JBrowse link
G Pbk PDZ binding kinase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PBK mRNA CTD PMID:29877212 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pcbp1 poly(rC) binding protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PCBP1 mRNA CTD PMID:15215175 NCBI chr 4:118,972,698...118,974,722
Ensembl chr 4:118,972,661...118,976,500
JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PCCA mRNA CTD PMID:33945839 NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PCK1 mRNA CTD PMID:15215175 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pclaf PCNA clamp associated factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PCLAF mRNA CTD PMID:29877212 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PCNA mRNA CTD PMID:15215175 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcp4 Purkinje cell protein 4 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PCP4 mRNA CTD PMID:15059925 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
JBrowse link
G Pdcd1 programmed cell death 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PDCD1 mRNA CTD PMID:20816883 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PDE10A mRNA CTD PMID:15215175 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression
increases expression
EXP
IEP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PDGFA mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PDGFA protein
PhIP increases expression of Pdgfa mRNA and protein in rat mammary gland
CTD
RGD
PMID:12376462 PMID:15215175 PMID:12376462 RGD:2292404 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PDIA4 mRNA CTD PMID:15215175 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdzd7 PDZ domain containing 7 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PDZD7 mRNA CTD PMID:20816883 NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PEBP1 mRNA CTD PMID:12376462 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR protein alternative form
fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR protein alternative form]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR protein
CTD PMID:15319301 PMID:15637090 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb1 prohibitin 1 increases expression
increases expression
EXP
IEP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PHB1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PHB1 protein
PhIP increases expression of Phb1 mRNA and protein in rat mammary gland
CTD
RGD
PMID:12376462 PMID:12376462 RGD:2292404 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PHGDH mRNA CTD PMID:15215175 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PIK3R1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PIK3R1 protein CTD PMID:12606953 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase affects response to substance ISO PIM1 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:8895492 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PKM mRNA CTD PMID:15215175 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plcb1 phospholipase C beta 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PLCB1 mRNA CTD PMID:15059925 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plk2 polo-like kinase 2 increases expression
increases expression
EXP
IEP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PLK2 mRNA
PhIP increases expression of Plk2 mRNA and protein in rat mammary gland
CTD
RGD
PMID:12376462 PMID:12376462 RGD:2292404 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Polh DNA polymerase eta affects activity ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the activity of POLH protein CTD PMID:19628463 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723
JBrowse link
G Polk DNA polymerase kappa affects activity ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the activity of POLK protein CTD PMID:19628463 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:9581821 PMID:10503888 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Poted POTE ankyrin domain family member D decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of POTED mRNA CTD PMID:20816883 NCBI chr17:57,942,124...57,975,149
Ensembl chr17:57,942,162...57,975,654
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PPARA mRNA CTD PMID:11137312 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppic peptidylprolyl isomerase C increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PPIC mRNA CTD PMID:15215175 NCBI chr18:46,842,410...46,855,016
Ensembl chr18:46,842,409...46,855,017
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PRC1 mRNA CTD PMID:29877212 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prcc proline rich mitotic checkpoint control factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PRCC mRNA CTD PMID:15215175 NCBI chr 2:173,326,261...173,351,799
Ensembl chr 2:173,326,259...173,351,825
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PRDX2 mRNA CTD PMID:15215175 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PRKAR2B mRNA CTD PMID:20816883 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prl prolactin multiple interactions ISO
EXP
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in decreased expression of BAX protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased activity of STAT5A protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased expression of BCL2 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in increased expression of STAT5A protein modified form
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased secretion of PRL protein]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of and results in increased secretion of PRL protein; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of and results in increased secretion of PRL protein]
CTD PMID:11751460 PMID:17909072 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PSAT1 mRNA CTD PMID:29877212 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMA2 mRNA CTD PMID:15215175 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMA6 mRNA CTD PMID:15215175 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMB1 mRNA CTD PMID:15215175 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMB2 mRNA CTD PMID:15215175 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMB4 mRNA CTD PMID:15215175 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMB6 mRNA CTD PMID:15215175 NCBI chr10:55,239,274...55,241,581
Ensembl chr10:55,239,241...55,241,586
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSMB9 mRNA CTD PMID:15215175 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PSME1 mRNA CTD PMID:15215175 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTBP1 mRNA CTD PMID:12376462 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
JBrowse link
G Pten phosphatase and tensin homolog decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PTEN protein CTD PMID:22581815 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptger1 prostaglandin E receptor 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTGER1 mRNA CTD PMID:11751431 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptges3 prostaglandin E synthase 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTGES3 mRNA CTD PMID:15215175 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases metabolic processing ISO PTGS1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:11159734 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing
multiple interactions
increases expression
ISO PTGS2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTGS2 protein
fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTGS2 protein]
CTD PMID:11159734 PMID:15459021 PMID:20951759 PMID:21081470 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of PTPRM mRNA CTD PMID:29877212 NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698
JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAB11A mRNA CTD PMID:15215175 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Rab1a RAB1A, member RAS oncogene family increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAB1A mRNA CTD PMID:15215175 NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248
JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAB1B mRNA CTD PMID:15215175 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
JBrowse link
G Rab2a RAB2A, member RAS oncogene family increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAB2 mRNA CTD PMID:15215175 NCBI chr 5:21,676,219...21,738,833
Ensembl chr 5:21,676,129...21,739,899
JBrowse link
G Rac2 Rac family small GTPase 2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAC2 mRNA CTD PMID:15215175 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RACGAP1 mRNA CTD PMID:29877212 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rack1 receptor for activated C kinase 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RACK1 mRNA CTD PMID:15215175 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RAD23B mRNA CTD PMID:20816883 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases phosphorylation ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of RAF1 protein CTD PMID:22307971 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Ralb RAS like proto-oncogene B increases expression
decreases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RALB mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RALB mRNA
CTD PMID:15215175 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RAN mRNA CTD PMID:12376462 PMID:15215175 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RAPGEF1 mRNA CTD PMID:20816883 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Rasa1 RAS p21 protein activator 1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RASA1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RASA1 protein CTD PMID:12606953 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RASGRF2 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RASGRF2 protein CTD PMID:12606953 NCBI chr 2:23,113,613...23,361,537
Ensembl chr 2:23,117,004...23,361,240
JBrowse link
G RatNP-3b defensin RatNP-3 precursor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RATNP-3B mRNA CTD PMID:15059925 NCBI chr16:70,544,364...70,546,533
Ensembl chr16:70,513,888...70,546,522
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
increases expression
ISO
EXP
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased phosphorylation of RB1 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RB1 protein modified form
CTD PMID:14522882 PMID:15635149 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RBBP4 mRNA CTD PMID:15215175 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284
JBrowse link
G Rbm14 RNA binding motif protein 14 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RBM14 mRNA CTD PMID:20816883 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
JBrowse link
G Rbp1 retinol binding protein 1 increases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RBP1 mRNA; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RBP1 protein
PhIP increases expression of Rbp1 mRNA and protein in rat mammary gland
CTD
RGD
PMID:12376462 PMID:12376462 RGD:2292404 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Rbp7 retinol binding protein 7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RBP7 mRNA CTD PMID:15215175 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RELA CTD PMID:20715105 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1308564 similar to L-amino acid oxidase 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RGD1308564 mRNA CTD PMID:33945839 NCBI chr10:42,459,948...42,477,215
Ensembl chr10:42,459,781...42,477,177
JBrowse link
G Rhoa ras homolog family member A decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RHOA mRNA CTD PMID:15215175 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoj ras homolog family member J decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RHOJ mRNA CTD PMID:15059925 NCBI chr 6:94,035,307...94,117,642
Ensembl chr 6:94,035,483...94,118,275
JBrowse link
G Rims4 regulating synaptic membrane exocytosis 4 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RIMS4 mRNA CTD PMID:20816883 NCBI chr 3:152,520,982...152,585,068
Ensembl chr 3:152,524,095...152,584,780
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RND3 mRNA CTD PMID:15215175 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf186 ring finger protein 186 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RNF186 mRNA CTD PMID:20816883 NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716
JBrowse link
G Rnf34 ring finger protein 34 decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RNF34 mRNA CTD PMID:20816883 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Rpgr retinitis pigmentosa GTPase regulator decreases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RPGR mRNA CTD PMID:20816883 NCBI chr  X:12,566,447...12,628,171
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Rpgrip1 RPGR interacting protein 1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPGRIP1 mRNA CTD PMID:20816883 NCBI chr15:24,814,576...24,867,522
Ensembl chr15:24,814,614...24,868,605
JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL10A mRNA CTD PMID:15215175 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl12 ribosomal protein L12 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL12 mRNA CTD PMID:15215175 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL13 mRNA CTD PMID:15215175 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl13a ribosomal protein L13A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL13A mRNA CTD PMID:15215175 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Rpl19 ribosomal protein L19 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL19 mRNA CTD PMID:15215175 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rpl21 ribosomal protein L21 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL21 mRNA CTD PMID:15215175 NCBI chr12:8,268,641...8,272,290
Ensembl chr12:8,267,196...8,272,281
JBrowse link
G Rpl22 ribosomal protein L22 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL22 mRNA CTD PMID:15215175 NCBI chr 5:162,835,251...162,841,977
Ensembl chr 5:162,833,740...162,843,368
JBrowse link
G Rpl26 ribosomal protein L26 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL26 mRNA CTD PMID:15215175 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Rpl27a ribosomal protein L27A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL27A mRNA CTD PMID:15215175 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl28 ribosomal protein L28 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL28 mRNA CTD PMID:15215175 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpl3 ribosomal protein L3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL3 mRNA CTD PMID:15215175 NCBI chr 7:111,622,257...111,627,639
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl35 ribosomal protein L35 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL35 mRNA CTD PMID:15215175 NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243
JBrowse link
G Rpl35a ribosomal protein L35A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL35A mRNA CTD PMID:15215175 NCBI chr11:67,726,034...67,730,023
Ensembl chr11:67,726,032...67,729,942
JBrowse link
G Rpl36 ribosomal protein L36 decreases expression
increases expression
EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RPL36 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL36 mRNA
CTD PMID:15215175 NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
JBrowse link
G Rpl37a ribosomal protein L37A increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL37A mRNA CTD PMID:15215175
G Rpl41 ribosomal protein L41 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL41 mRNA CTD PMID:15215175 NCBI chr 7:977,885...978,965 JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL6 mRNA CTD PMID:12376462 PMID:15215175 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rpl7 ribosomal protein L7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL7 mRNA CTD PMID:15215175 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPL8 mRNA CTD PMID:15215175 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPLP0 mRNA CTD PMID:15215175 NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPLP1 mRNA CTD PMID:15215175 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPLP2 mRNA CTD PMID:15215175 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
JBrowse link
G Rps11 ribosomal protein S11 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS11 mRNA CTD PMID:15215175 NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874
JBrowse link
G Rps14 ribosomal protein S14 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS14 mRNA CTD PMID:15215175 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
JBrowse link
G Rps15 ribosomal protein S15 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS15 mRNA CTD PMID:15215175 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps17 ribosomal protein S17 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS17 mRNA CTD PMID:15215175 NCBI chr 1:135,295,920...135,298,506
Ensembl chr 1:135,295,919...135,298,535
JBrowse link
G Rps19 ribosomal protein S19 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS19 mRNA CTD PMID:15215175 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps2 ribosomal protein S2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS2 mRNA CTD PMID:15215175 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Rps23 ribosomal protein S23 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS23 mRNA CTD PMID:15215175 NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
JBrowse link
G Rps24 ribosomal protein S24 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS24 mRNA CTD PMID:15215175 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279
JBrowse link
G Rps29 ribosomal protein S29 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS29 mRNA CTD PMID:15215175 NCBI chr 6:87,635,229...87,636,605
Ensembl chr 6:87,635,230...87,636,636
JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS3 mRNA CTD PMID:15215175 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS3A mRNA CTD PMID:15215175 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps5 ribosomal protein S5 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS5 mRNA CTD PMID:15215175 NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
increases expression
EXP [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of RPS6 mRNA; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in increased expression of RPS6 mRNA
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS6 mRNA
CTD PMID:12097258 PMID:15215175 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
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G Rps7 ribosomal protein S7 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPS7 mRNA CTD PMID:15215175 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RPSA mRNA CTD PMID:15215175 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RRM2 mRNA CTD PMID:29877212 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G RT1-Da RT1 class II, locus Da decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of RT1-DA mRNA CTD PMID:15215175 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G S100a1 S100 calcium binding protein A1 increases expression ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of S100A1 mRNA CTD PMID:20816883 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of S100A9 mRNA CTD PMID:15059925 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression EXP 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of S1PR1 mRNA CTD PMID:12376462