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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dipicolinic acid
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Accession:CHEBI:46837 term browser browse the term
Definition:A pyridinedicarboxylic acid carrying two carboxy groups at positions 2 and 6.
Synonyms:related_synonym: 2,6-Dipicolinic acid;   2,6-dicarboxypyridine;   2,6-pyridinedicarboxylic acid;   Formula=C7H5NO4;   InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12);   InChIKey=WJJMNDUMQPNECX-UHFFFAOYSA-N;   PYRIDINE-2,6-DICARBOXYLIC ACID;   SMILES=OC(=O)c1cccc(n1)C(O)=O
 alt_id: CHEBI:36171;   CHEBI:44858
 xref: Beilstein:131629;   CAS:499-83-2;   DrugBank:DB04267;   Gmelin:50798;   HMDB:HMDB0033161
 xref_mesh: MESH:C004860
 xref: PDBeChem:PDC;   PMID:23396907;   PMID:24123749;   Patent:US5298478;   Reaxys:131629;   Wikipedia:Dipicolinic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:46835


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dipicolinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 multiple interactions
decreases activity
ISO dipicolinic acid inhibits the reaction [[GLUD1 protein co-treated with Ketoglutaric Acids co-treated with NADP co-treated with Aminooxyacetic Acid] affects the reaction [Carbon Tetrachloride affects the abundance of Ammonia]]
dipicolinic acid results in decreased activity of GLUD1 protein
CTD PMID:26639393 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO dipicolinic acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      chemical role 19336
        environmental contaminant 18636
          pyridine 50
            pyridinedicarboxylic acid 30
              dipicolinic acid 2
                (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid 0
                2,3,4,5-tetrahydrodipicolinic acid + 0
                3-(2-deoxy-5-O-phosphonoribofuranosyl)pyridine-2,6-dicarboxylic acid 0
                dihydrodipicolinic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      dicarboxylic acids and O-substituted derivatives 10364
                                        dicarboxylic acid 10357
                                          pyridinedicarboxylic acid 30
                                            dipicolinic acid 2
                                              (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid 0
                                              2,3,4,5-tetrahydrodipicolinic acid + 0
                                              3-(2-deoxy-5-O-phosphonoribofuranosyl)pyridine-2,6-dicarboxylic acid 0
                                              dihydrodipicolinic acid + 0
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