|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity multiple interactions |
ISO |
Isradipine results in decreased activity of ABCB11 protein Isradipine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] |
CTD |
PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
|
|
G |
Ahr |
aryl hydrocarbon receptor |
increases activity |
ISO |
Isradipine results in increased activity of AHR protein |
CTD |
PMID:27732883 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Cacna1e |
calcium voltage-gated channel subunit alpha1 E |
multiple interactions |
EXP |
Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]; omega-conotoxin-MVIIC promotes the reaction [Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]] |
CTD |
PMID:11179973 |
|
NCBI chr13:66,574,659...67,063,443
|
|
G |
Cacna1f |
calcium voltage-gated channel subunit alpha1 F |
multiple interactions |
ISO |
Isradipine inhibits the reaction [CACNA1F protein results in increased transport of Barium] |
CTD |
PMID:14744918 |
|
NCBI chr X:14,868,096...14,896,413
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression decreases activity |
ISO |
Isradipine results in increased expression of CYP1A1 mRNA Isradipine results in decreased activity of CYP1A1 protein |
CTD |
PMID:27732883 PMID:33814510 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression |
ISO |
Isradipine results in increased expression of CYP1A2 mRNA |
CTD |
PMID:27732883 |
|
NCBI chr 8:66,971,261...66,978,149
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity |
ISO |
Isradipine results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
|
NCBI chr 6:21,093,927...21,103,091
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Isradipine results in increased expression of CYP2B6 mRNA; Isradipine results in increased expression of CYP2B6 protein |
CTD |
PMID:27732883 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases expression multiple interactions affects metabolic processing |
ISO |
Isradipine results in increased expression of CYP3A4 mRNA Isradipine results in increased expression of and results in decreased activity of CYP3A4 protein CYP3A4 protein affects the metabolism of Isradipine |
CTD |
PMID:15286053 PMID:27732883 |
|
NCBI chr12:14,321,771...14,343,886
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
increases secretion |
ISO |
Isradipine results in increased secretion of FGF2 protein |
CTD |
PMID:15257873 |
|
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Isradipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 5:5,835,642...6,069,693
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
Isradipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 7:25,733,471...25,829,440
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
Isradipine results in increased activity of NR1I2 protein |
CTD |
PMID:27732883 |
|
NCBI chr11:75,965,717...76,006,733
|
|
G |
Penk |
proenkephalin |
multiple interactions |
EXP |
Isradipine inhibits the reaction [Oxidopamine results in increased expression of PENK mRNA] |
CTD |
PMID:18947822 |
|
NCBI chr 5:21,981,381...21,987,074
|
|
G |
Ren |
renin |
increases activity |
ISO |
Isradipine results in increased activity of REN protein |
CTD |
PMID:2550243 |
|
NCBI chr13:47,348,312...47,359,539
|
|
G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
Isradipine promotes the reaction [Cyclic AMP results in increased expression of STAR protein] |
CTD |
PMID:19822634 |
|
NCBI chr16:72,969,824...72,974,447
|
|