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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dolasetron
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Accession:CHEBI:4682 term browser browse the term
Definition:A heteroarenecarboxylate ester that has formula C19H20N2O3.
Synonyms:related_synonym: Formula=C19H20N2O3;   InChI=1S/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2;   InChIKey=UKTAZPQNNNJVKR-UHFFFAOYSA-N;   MDL 73,147EF;   SMILES=O=C(OC1CC2CC3CC(C1)N2CC3=O)c1c[nH]c2ccccc12;   anemet;   anzemet;   anzemet hydrate;   dolasetron mesilate;   dolasetron mesylate;   dolasetron mesylate hydrate;   dolasetron methanesulfonate hydrate
 xref: CAS:115956-12-2;   Drug_Central:3931;   KEGG:C07866;   KEGG:D07867
 xref_mesh: MESH:C060344


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dolasetron term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO dolasetron results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      atom 19873
        nonmetal atom 19751
          nitrogen atom 18640
            nitrogen molecular entity 18640
              organonitrogen compound 18414
                organonitrogen heterocyclic compound 17579
                  quinolizines 5
                    dolasetron 1
                      dolasetron methanesulfonate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic molecule 19586
                              organic cyclic compound 19395
                                organic heterocyclic compound 18511
                                  organic heteropolycyclic compound 17900
                                    organic heterobicyclic compound 16826
                                      benzopyrrole 9549
                                        indoles 9219
                                          dolasetron 1
                                            dolasetron methanesulfonate 0
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