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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxypolyether
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Accession:CHEBI:46792 term browser browse the term
Definition:A hydroxyether compound containing more than one ether group.


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diethylene glycol monoethyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase increases activity EXP carbitol results in increased activity of GPT protein CTD PMID:25959454 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
Nonidet P-40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO Nonidet P-40 results in decreased expression of ARNT mRNA CTD PMID:26552463 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Nonidet P-40 results in increased expression of ATF4 mRNA CTD PMID:26552463 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Nonidet P-40 results in increased expression of ATF6 mRNA CTD PMID:26552463 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Nonidet P-40 results in increased expression of ATF6B mRNA CTD PMID:26552463 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Atg12 autophagy related 12 increases expression ISO Nonidet P-40 results in increased expression of ATG12 mRNA CTD PMID:26552463 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg5 autophagy related 5 decreases expression ISO Nonidet P-40 results in decreased expression of ATG5 mRNA CTD PMID:26552463 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 decreases expression ISO Nonidet P-40 results in decreased expression of ATG7 mRNA CTD PMID:26552463 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Nonidet P-40 results in decreased expression of ATR mRNA CTD PMID:26552463 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Nonidet P-40 results in increased expression of BBC3 mRNA CTD PMID:26552463 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Becn1 beclin 1 increases expression ISO Nonidet P-40 results in increased expression of BECN1 mRNA CTD PMID:26552463 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Nonidet P-40 results in increased expression of BID mRNA CTD PMID:26552463 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Nonidet P-40 results in increased expression of BNIP3L mRNA CTD PMID:26552463 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO Nonidet P-40 results in decreased expression of CA9 mRNA CTD PMID:26552463 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calr calreticulin decreases expression ISO Nonidet P-40 results in decreased expression of CALR mRNA CTD PMID:26552463 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp1 caspase 1 decreases expression ISO Nonidet P-40 results in decreased expression of CASP1 mRNA CTD PMID:26552463 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Nonidet P-40 results in increased expression of CCL2 mRNA CTD PMID:26552463 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Nonidet P-40 results in increased expression of CDKN1A mRNA CTD PMID:26552463 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Nonidet P-40 results in increased expression of CHEK2 mRNA CTD PMID:26552463 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Crp C-reactive protein increases expression ISO Nonidet P-40 results in increased expression of CRP mRNA CTD PMID:26552463 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of DDB2 mRNA CTD PMID:26552463 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Nonidet P-40 results in increased expression of DDIT3 mRNA CTD PMID:26552463 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Nonidet P-40 results in increased expression of DNAJC3 mRNA CTD PMID:26552463 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Epo erythropoietin decreases expression ISO Nonidet P-40 results in decreased expression of EPO mRNA CTD PMID:26552463 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Nonidet P-40 results in increased expression of GADD45A mRNA CTD PMID:26552463 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Nonidet P-40 results in decreased expression of GCLC mRNA CTD PMID:26552463 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of GRB2 mRNA CTD PMID:26552463 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Nonidet P-40 results in increased expression of HMOX1 mRNA CTD PMID:26552463 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Nonidet P-40 results in increased expression of HSP90AA1 mRNA CTD PMID:26552463 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO Nonidet P-40 results in increased expression of HSPA4 mRNA CTD PMID:26552463 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO Nonidet P-40 results in increased expression of HSPA4L mRNA CTD PMID:26552463 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Nonidet P-40 results in decreased expression of HSPA5 mRNA CTD PMID:26552463 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Nonidet P-40 results in increased expression of HUS1 mRNA CTD PMID:26552463 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825
JBrowse link
G Ifng interferon gamma decreases expression ISO Nonidet P-40 results in decreased expression of IFNG mRNA CTD PMID:26552463 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Nonidet P-40 results in decreased expression of IL1A mRNA CTD PMID:26552463 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 increases expression ISO Nonidet P-40 results in increased expression of IL6 mRNA CTD PMID:26552463 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Nonidet P-40 results in decreased expression of LDHA mRNA CTD PMID:26552463 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Nonidet P-40 results in increased expression of MCL1 mRNA CTD PMID:26552463 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Nonidet P-40 results in decreased expression of MMP9 mRNA CTD PMID:26552463 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease increases expression ISO Nonidet P-40 results in increased expression of MRE11A mRNA CTD PMID:26552463 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489
JBrowse link
G Nbn nibrin increases expression ISO Nonidet P-40 results in increased expression of NBN mRNA CTD PMID:26552463 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Nonidet P-40 results in increased expression of NQO1 mRNA CTD PMID:26552463 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nonidet P-40 results in decreased expression of PARP1 mRNA CTD PMID:26552463 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component increases expression ISO Nonidet P-40 results in increased expression of RAD17 mRNA CTD PMID:26552463 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Nonidet P-40 results in decreased expression of RAD51 mRNA CTD PMID:26552463 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO Nonidet P-40 results in increased expression of RAD9A mRNA CTD PMID:26552463 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Nonidet P-40 results in decreased expression of SERPINE1 mRNA CTD PMID:26552463 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Nonidet P-40 results in increased expression of SLC2A1 mRNA CTD PMID:26552463 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Nonidet P-40 results in decreased expression of SQSTM1 mRNA CTD PMID:26552463 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Nonidet P-40 results in decreased expression of TLR4 mRNA CTD PMID:26552463 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF10A mRNA CTD PMID:26552463 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF1A mRNA CTD PMID:26552463 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Nonidet P-40 results in decreased expression of TP53 mRNA CTD PMID:26552463 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Nonidet P-40 results in decreased expression of TXN mRNA CTD PMID:26552463 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Nonidet P-40 results in increased expression of TXNRD1 mRNA CTD PMID:26552463 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases expression ISO Nonidet P-40 results in decreased expression of ULK1 mRNA CTD PMID:26552463 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nonidet P-40 results in decreased expression of VEGFA mRNA CTD PMID:26552463 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression ISO Nonidet P-40 results in decreased expression of XPC mRNA CTD PMID:26552463 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
polysorbate 40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO polysorbate 40 results in increased expression of HMOX1 mRNA CTD PMID:17225922 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
Triton X-100 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnfn cornifelin increases expression ISO Octoxynol results in increased expression of CNFN mRNA; Octoxynol results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 1:82,234,032...82,236,602
Ensembl chr 1:82,234,032...82,236,179
JBrowse link
G Egr1 early growth response 1 increases expression ISO Octoxynol results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ezr ezrin increases expression ISO Octoxynol results in increased expression of EZR mRNA CTD PMID:29893927 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Octoxynol results in decreased expression of FN1 mRNA CTD PMID:25377654 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO Octoxynol results in increased secretion of IL1A protein CTD PMID:23999410 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Octoxynol results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Octoxynol results in increased expression of SCD mRNA CTD PMID:29155129 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Octoxynol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:17038422 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      atom 19784
        nonmetal atom 19659
          oxygen atom 19323
            oxygen molecular entity 19323
              organooxygen compound 18778
                ether 15940
                  polyether 244
                    hydroxypolyether 66
                      2-(2-methoxyethoxy)ethanol 0
                      Nonidet P-40 58
                      diethylene glycol monoethyl ether 1
                      heptacosaethylene glycol monomethyl ether 0
                      hexaethylene glycol monomethyl ether 0
                      hydroxypolyether aldehyde + 0
                      laureth-5 0
                      methoxypoly(ethylene glycol) 0
                      nonaethylene glycol monomethyl ether + 0
                      octaethyleneglycol monododecyl ether 0
                      pentaerythritol ethoxylate (3/4 EO/OH) 0
                      pentaerythritol propoxylate (5/4 PO/OH) 0
                      polidocanol 0
                      poly(ethylene glycol monomethacrylate) 0
                      poly(ethylene glycol) + 65
                      poly(propylene glycol) macromolecule + 0
                      polysorbate + 1
                      tergitol + 0
                      tetraethylene glycol monooctyl ether 0
                      tetratriacontaethylene glycol monomethyl ether 0
                      triethylene glycol monomethyl ether 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organochalcogen compound 18856
                                organooxygen compound 18778
                                  ether 15940
                                    polyether 244
                                      hydroxypolyether 66
                                        2-(2-methoxyethoxy)ethanol 0
                                        Nonidet P-40 58
                                        diethylene glycol monoethyl ether 1
                                        heptacosaethylene glycol monomethyl ether 0
                                        hexaethylene glycol monomethyl ether 0
                                        hydroxypolyether aldehyde + 0
                                        laureth-5 0
                                        methoxypoly(ethylene glycol) 0
                                        nonaethylene glycol monomethyl ether + 0
                                        octaethyleneglycol monododecyl ether 0
                                        pentaerythritol ethoxylate (3/4 EO/OH) 0
                                        pentaerythritol propoxylate (5/4 PO/OH) 0
                                        polidocanol 0
                                        poly(ethylene glycol monomethacrylate) 0
                                        poly(ethylene glycol) + 65
                                        poly(propylene glycol) macromolecule + 0
                                        polysorbate + 1
                                        tergitol + 0
                                        tetraethylene glycol monooctyl ether 0
                                        tetratriacontaethylene glycol monomethyl ether 0
                                        triethylene glycol monomethyl ether 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.