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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-ethoxyethanol
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Accession:CHEBI:46788 term browser browse the term
Definition:A hydroxyether that is the ethyl ether derivative of ethylene glycol.
Synonyms:related_synonym: 2-ethoxyethyl alcohol;   2EE;   Cellosolve;   Formula=C4H10O2;   HOCH2CH2OC2H5;   InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3;   InChIKey=ZNQVEEAIQZEUHB-UHFFFAOYSA-N;   Oxitol;   SMILES=CCOCCO;   beta-ethoxyethanol;   ethylene glycol ethyl ether;   ethylene glycol monoethyl ether
 alt_id: CHEBI:34272;   CHEBI:42340
 xref: Beilstein:1098271;   CAS:110-80-5;   DrugBank:DB02249;   Gmelin:82142;   HMDB:HMDB0031213;   KEGG:C14687
 xref_mesh: MESH:C021296
 xref: PDBeChem:ETX;   PMID:12209180;   PMID:24399739;   PMID:2625497;   PMID:7151721;   Reaxys:1098271;   Wikipedia:2-Ethoxyethanol



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2-ethoxyethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of AKT2 mRNA CTD PMID:19643169 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 increases expression EXP 2-ethoxyethanol results in increased expression of AKT3 mRNA CTD PMID:19643169 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases reaction ISO ALDH2 protein promotes the reaction 2-ethoxyethanol CTD PMID:17878629 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G App amyloid beta precursor protein increases expression EXP 2-ethoxyethanol results in increased expression of APP mRNA CTD PMID:19643169 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression EXP 2-ethoxyethanol results in increased expression of ARF3 mRNA CTD PMID:19643169 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Atf2 activating transcription factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of ATF2 mRNA CTD PMID:19643169 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bag6 BAG cochaperone 6 increases expression EXP 2-ethoxyethanol results in increased expression of BAG6 mRNA CTD PMID:19643169 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP 2-ethoxyethanol results in increased expression of BCL2L1 mRNA CTD PMID:19643169 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Cat catalase decreases activity EXP 2-ethoxyethanol results in decreased activity of CAT protein CTD PMID:20172899 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression EXP 2-ethoxyethanol results in increased expression of CAV mRNA CTD PMID:19643169 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression EXP 2-ethoxyethanol results in increased expression of CEBPG mRNA CTD PMID:19643169 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Cel carboxyl ester lipase increases expression EXP 2-ethoxyethanol results in increased expression of CEL mRNA CTD PMID:19643169 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of CHP1 mRNA CTD PMID:19643169 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Cltc clathrin heavy chain increases expression EXP 2-ethoxyethanol results in increased expression of CLTC mRNA CTD PMID:19643169 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1A1 mRNA CTD PMID:19643169 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Csnk1d casein kinase 1, delta increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1D mRNA CTD PMID:19643169 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1G3 mRNA CTD PMID:19643169 NCBI chr18:47,287,466...47,386,538
Ensembl chr18:47,299,579...47,386,535
JBrowse link
G Cttn cortactin increases expression EXP 2-ethoxyethanol results in increased expression of CTTN mRNA CTD PMID:19643169 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP 2-ethoxyethanol results in increased expression of DHCR7 mRNA CTD PMID:19643169 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of DYNC1LI1 mRNA CTD PMID:19643169 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
JBrowse link
G Eloa elongin A increases expression EXP 2-ethoxyethanol results in increased expression of ELOA mRNA CTD PMID:19643169 NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765
JBrowse link
G Eno2 enolase 2 increases expression EXP 2-ethoxyethanol results in increased expression of ENO2 mRNA CTD PMID:19643169 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Epn2 epsin 2 increases expression EXP 2-ethoxyethanol results in increased expression of EPN2 mRNA CTD PMID:19643169 NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642
JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of GATA4 mRNA CTD PMID:19643169 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP 2-ethoxyethanol results in increased expression of GATA6 mRNA CTD PMID:19643169 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression EXP 2-ethoxyethanol results in increased expression of GDI2 mRNA CTD PMID:19643169 NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
JBrowse link
G Hk1 hexokinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of HK1 mRNA CTD PMID:19643169 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of HK2 mRNA CTD PMID:19643169 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of IGF2 mRNA CTD PMID:19643169 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Jak2 Janus kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of JAK2 mRNA CTD PMID:19643169 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of LYN mRNA CTD PMID:19643169 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 decreases expression EXP 2-ethoxyethanol results in decreased expression of MAP3K12 mRNA CTD PMID:19643169 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK1 mRNA CTD PMID:19643169 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK10 mRNA CTD PMID:19643169 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression EXP 2-ethoxyethanol results in increased expression of MXI1 mRNA CTD PMID:19643169 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Nab1 Ngfi-A binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of NAB1 mRNA CTD PMID:19643169 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
JBrowse link
G Nfia nuclear factor I/A increases expression EXP 2-ethoxyethanol results in increased expression of NFIA mRNA CTD PMID:19643169 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression EXP 2-ethoxyethanol results in increased expression of NR2F2 mRNA CTD PMID:19643169 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PAK2 mRNA CTD PMID:19643169 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PFKFB2 mRNA CTD PMID:19643169 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression EXP 2-ethoxyethanol results in increased expression of PLA2G4A mRNA CTD PMID:19643169 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plcb3 phospholipase C beta 3 increases expression EXP 2-ethoxyethanol results in increased expression of PLCB3 mRNA CTD PMID:19643169 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Pou2f3 POU class 2 homeobox 3 increases expression EXP 2-ethoxyethanol results in increased expression of POU2F3 mRNA CTD PMID:19643169 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases expression EXP 2-ethoxyethanol results in increased expression of PRKAR2A mRNA CTD PMID:19643169 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP 2-ethoxyethanol results in increased expression of RAB5A mRNA CTD PMID:19643169 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rnf4 ring finger protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of RNF4 mRNA CTD PMID:19643169 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of ROS1 mRNA CTD PMID:19643169 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 increases expression EXP 2-ethoxyethanol results in increased expression of SEC14L2 mRNA CTD PMID:19643169 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SIK1 mRNA CTD PMID:19643169 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Snrk SNF related kinase increases expression EXP 2-ethoxyethanol results in increased expression of SNRK mRNA CTD PMID:19643169 NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323
JBrowse link
G Snx16 sorting nexin 16 increases expression EXP 2-ethoxyethanol results in increased expression of SNX16 mRNA CTD PMID:19643169 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SOAT1 mRNA CTD PMID:19643169 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP 2-ethoxyethanol results in increased expression of STK17B mRNA CTD PMID:19643169 NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:55,307,668...55,338,031
JBrowse link
G Stx2 syntaxin 2 increases expression EXP 2-ethoxyethanol results in increased expression of STX2 mRNA CTD PMID:19643169 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of STXBP1 mRNA CTD PMID:19643169 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP1 mRNA CTD PMID:19643169 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737
JBrowse link
G Sycp2 synaptonemal complex protein 2 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP2 mRNA CTD PMID:19643169 NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789
JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP3 mRNA CTD PMID:19643169 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor increases expression EXP 2-ethoxyethanol results in increased expression of TLE4 mRNA CTD PMID:19643169 NCBI chr 1:211,661,738...211,798,458
Ensembl chr 1:211,661,746...211,797,862
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP 2-ethoxyethanol results in increased expression of TMED2 mRNA CTD PMID:19643169 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Wt1 WT1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of WT1 mRNA CTD PMID:19643169 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Yy1 YY1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of YY1 mRNA CTD PMID:19643169 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      application 19737
        solvent 16667
          ethylene glycol 137
            2-ethoxyethanol 62
              2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      chalcogen 19673
                        oxygen atom 19644
                          oxygen molecular entity 19644
                            hydroxides 19375
                              organic hydroxy compound 18890
                                polyol 11027
                                  diol 3352
                                    glycol 3117
                                      glycol ether 912
                                        2-ethoxyethanol 62
                                          2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
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