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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-ethoxyethanol
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Accession:CHEBI:46788 term browser browse the term
Definition:A hydroxyether that is the ethyl ether derivative of ethylene glycol.
Synonyms:related_synonym: 2-ethoxyethyl alcohol;   2EE;   Cellosolve;   Formula=C4H10O2;   HOCH2CH2OC2H5;   InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3;   InChIKey=ZNQVEEAIQZEUHB-UHFFFAOYSA-N;   Oxitol;   SMILES=CCOCCO;   beta-ethoxyethanol;   ethylene glycol ethyl ether;   ethylene glycol monoethyl ether
 alt_id: CHEBI:34272;   CHEBI:42340
 xref: Beilstein:1098271;   CAS:110-80-5;   DrugBank:DB02249;   Gmelin:82142;   HMDB:HMDB0031213;   KEGG:C14687
 xref_mesh: MESH:C021296
 xref: PDBeChem:ETX;   PMID:12209180;   PMID:24399739;   PMID:2625497;   PMID:7151721;   Reaxys:1098271;   Wikipedia:2-Ethoxyethanol

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2-ethoxyethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of AKT2 mRNA CTD PMID:19643169 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 increases expression EXP 2-ethoxyethanol results in increased expression of AKT3 mRNA CTD PMID:19643169 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases reaction ISO ALDH2 protein promotes the reaction 2-ethoxyethanol CTD PMID:17878629 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G App amyloid beta precursor protein increases expression EXP 2-ethoxyethanol results in increased expression of APP mRNA CTD PMID:19643169 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression EXP 2-ethoxyethanol results in increased expression of ARF3 mRNA CTD PMID:19643169 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467 		JBrowse link
G Atf2 activating transcription factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of ATF2 mRNA CTD PMID:19643169 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Bag6 BAG cochaperone 6 increases expression EXP 2-ethoxyethanol results in increased expression of BAG6 mRNA CTD PMID:19643169 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP 2-ethoxyethanol results in increased expression of BCL2L1 mRNA CTD PMID:19643169 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Cat catalase decreases activity EXP 2-ethoxyethanol results in decreased activity of CAT protein CTD PMID:20172899 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cav1 caveolin 1 increases expression EXP 2-ethoxyethanol results in increased expression of CAV mRNA CTD PMID:19643169 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression EXP 2-ethoxyethanol results in increased expression of CEBPG mRNA CTD PMID:19643169 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656 		JBrowse link
G Cel carboxyl ester lipase increases expression EXP 2-ethoxyethanol results in increased expression of CEL mRNA CTD PMID:19643169 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of CHP1 mRNA CTD PMID:19643169 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989 		JBrowse link
G Cltc clathrin heavy chain increases expression EXP 2-ethoxyethanol results in increased expression of CLTC mRNA CTD PMID:19643169 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1A1 mRNA CTD PMID:19643169 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345 		JBrowse link
G Csnk1d casein kinase 1, delta increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1D mRNA CTD PMID:19643169 NCBI chr10:110,147,786...110,182,413
Ensembl chr10:110,148,600...110,182,408 		JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1G3 mRNA CTD PMID:19643169 NCBI chr18:48,831,209...48,913,341
Ensembl chr18:48,853,418...48,911,122 		JBrowse link
G Cttn cortactin increases expression EXP 2-ethoxyethanol results in increased expression of CTTN mRNA CTD PMID:19643169 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP 2-ethoxyethanol results in increased expression of DHCR7 mRNA CTD PMID:19643169 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of DYNC1LI1 mRNA CTD PMID:19643169 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806 		JBrowse link
G Eloa elongin A increases expression EXP 2-ethoxyethanol results in increased expression of ELOA mRNA CTD PMID:19643169 NCBI chr 5:154,348,167...154,363,324
Ensembl chr 5:154,347,391...154,363,329 		JBrowse link
G Eno2 enolase 2 increases expression EXP 2-ethoxyethanol results in increased expression of ENO2 mRNA CTD PMID:19643169 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Epn2 epsin 2 increases expression EXP 2-ethoxyethanol results in increased expression of EPN2 mRNA CTD PMID:19643169 NCBI chr10:47,795,496...47,857,373
Ensembl chr10:47,795,524...47,857,326 		JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of GATA4 mRNA CTD PMID:19643169 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965 		JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP 2-ethoxyethanol results in increased expression of GATA6 mRNA CTD PMID:19643169 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338 		JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression EXP 2-ethoxyethanol results in increased expression of GDI2 mRNA CTD PMID:19643169 NCBI chr17:70,299,177...70,325,864
Ensembl chr17:70,299,183...70,325,855 		JBrowse link
G Hk1 hexokinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of HK1 mRNA CTD PMID:19643169 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649 		JBrowse link
G Hk2 hexokinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of HK2 mRNA CTD PMID:19643169 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of IGF2 mRNA CTD PMID:19643169 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911 		JBrowse link
G Jak2 Janus kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of JAK2 mRNA CTD PMID:19643169 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of LYN mRNA CTD PMID:19643169 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 decreases expression EXP 2-ethoxyethanol results in decreased expression of MAP3K12 mRNA CTD PMID:19643169 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK1 mRNA CTD PMID:19643169 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK10 mRNA CTD PMID:19643169 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression EXP 2-ethoxyethanol results in increased expression of MXI1 mRNA CTD PMID:19643169 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071 		JBrowse link
G Nab1 Ngfi-A binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of NAB1 mRNA CTD PMID:19643169 NCBI chr 9:53,906,073...53,945,474
Ensembl chr 9:53,906,073...53,945,473 		JBrowse link
G Nfia nuclear factor I/A increases expression EXP 2-ethoxyethanol results in increased expression of NFIA mRNA CTD PMID:19643169 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression EXP 2-ethoxyethanol results in increased expression of NR2F2 mRNA CTD PMID:19643169 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PAK2 mRNA CTD PMID:19643169 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PFKFB2 mRNA CTD PMID:19643169 NCBI chr13:47,413,453...47,440,682
Ensembl chr13:47,413,458...47,440,682 		JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression EXP 2-ethoxyethanol results in increased expression of PLA2G4A mRNA CTD PMID:19643169 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693 		JBrowse link
G Plcb3 phospholipase C beta 3 increases expression EXP 2-ethoxyethanol results in increased expression of PLCB3 mRNA CTD PMID:19643169 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910 		JBrowse link
G Pou2f3 POU class 2 homeobox 3 increases expression EXP 2-ethoxyethanol results in increased expression of POU2F3 mRNA CTD PMID:19643169 NCBI chr 8:47,412,063...47,495,042
Ensembl chr 8:47,410,220...47,494,982 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases expression EXP 2-ethoxyethanol results in increased expression of PRKAR2A mRNA CTD PMID:19643169 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP 2-ethoxyethanol results in increased expression of RAB5A mRNA CTD PMID:19643169 NCBI chr 9:5,910...6,065 JBrowse link
G Rnf4 ring finger protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of RNF4 mRNA CTD PMID:19643169 NCBI chr14:81,658,400...81,679,756
Ensembl chr14:81,660,354...81,679,082 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of ROS1 mRNA CTD PMID:19643169 NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 increases expression EXP 2-ethoxyethanol results in increased expression of SEC14L2 mRNA CTD PMID:19643169 NCBI chr14:84,335,594...84,360,354
Ensembl chr14:84,335,597...84,355,528 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SIK1 mRNA CTD PMID:19643169 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283 		JBrowse link
G Snrk SNF related kinase increases expression EXP 2-ethoxyethanol results in increased expression of SNRK mRNA CTD PMID:19643169 NCBI chr 8:130,749,806...130,805,225
Ensembl chr 8:130,749,838...130,803,597 		JBrowse link
G Snx16 sorting nexin 16 increases expression EXP 2-ethoxyethanol results in increased expression of SNX16 mRNA CTD PMID:19643169 NCBI chr 2:93,518,796...93,541,056
Ensembl chr 2:93,518,806...93,540,328 		JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SOAT1 mRNA CTD PMID:19643169 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783 		JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP 2-ethoxyethanol results in increased expression of STK17B mRNA CTD PMID:19643169 NCBI chr 9:60,399,261...60,430,081
Ensembl chr 9:60,399,261...60,430,081 		JBrowse link
G Stx2 syntaxin 2 increases expression EXP 2-ethoxyethanol results in increased expression of STX2 mRNA CTD PMID:19643169 NCBI chr12:31,324,203...31,360,249
Ensembl chr12:31,335,372...31,360,254 		JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of STXBP1 mRNA CTD PMID:19643169 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417 		JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP1 mRNA CTD PMID:19643169 NCBI chr 2:205,274,766...205,426,869
Ensembl chr 2:205,274,769...205,426,869 		JBrowse link
G Sycp2 synaptonemal complex protein 2 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP2 mRNA CTD PMID:19643169 NCBI chr 3:173,884,559...173,948,304
Ensembl chr 3:173,884,287...173,947,018 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP3 mRNA CTD PMID:19643169 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251 		JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor increases expression EXP 2-ethoxyethanol results in increased expression of TLE4 mRNA CTD PMID:19643169 NCBI chr 1:231,394,606...231,531,396
Ensembl chr 1:231,393,379...231,530,786 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP 2-ethoxyethanol results in increased expression of TMED2 mRNA CTD PMID:19643169 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297 		JBrowse link
G Wt1 WT1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of WT1 mRNA CTD PMID:19643169 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Yy1 YY1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of YY1 mRNA CTD PMID:19643169 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      application 19505
        solvent 16574
          ethylene glycol 136
            2-ethoxyethanol 62
              2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              organic hydroxy compound 18696
                                polyol 7820
                                  diol 2724
                                    glycol 2453
                                      ethylene glycol 136
                                        2-ethoxyethanol 62
                                          2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
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