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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:polyether
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Accession:CHEBI:46774 term browser browse the term
Definition:Any ether that contains more than one ether linkage.
Synonyms:related_synonym: polyethers



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(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cat catalase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Il10 interleukin 10 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
(S)-glaucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO glaucine results in increased activity of ABCB1 protein CTD PMID:23273999 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO Verapamil inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
decreases expression
decreases activity
increases activity
affects response to substance
multiple interactions
increases expression
ISO
EXP
ABCB1 protein results in increased transport of Verapamil
Verapamil results in decreased expression of ABCB1A mRNA
Verapamil results in decreased activity of ABCB1 protein; Verapamil results in decreased activity of ABCB1A protein
Verapamil results in increased activity of ABCB1 protein
ABCB1A protein affects the susceptibility to Verapamil
[Verapamil results in decreased activity of ABCB1 protein] inhibits the reaction [P-glycoprotein inducer and activator TX5 results in increased export of Rhodamine 123]; Verapamil inhibits the reaction [ABCB1 results in decreased susceptibility to Cadmium Chloride]
[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]; [Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]; Verapamil promotes the reaction [Vanadates results in decreased activity of ABCB1A protein]
Verapamil results in increased expression of ABCB1 mRNA
Verapamil analog results in increased activity of ABCB1 protein mutant form; Verapamil results in increased activity of ABCB1 protein
Verapamil results in decreased expression of ABCB1 protein
[Endosulfan co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [Endosulfan co-treated with Verapamil] results in decreased activity of ABCB1 protein; [phosalone co-treated with Verapamil] inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; [phosalone co-treated with Verapamil] results in decreased activity of ABCB1 protein; [Verapamil binds to and results in decreased activity of ABCB1 protein] inhibits the reaction [sodium arsenite promotes the reaction [ABCB1 protein results in increased secretion of calcein AM]]; [Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin; [Verapamil binds to and results in decreased activity of ABCB1 protein] which results in decreased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of Digoxin; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of hypaconitine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of mesaconitine; [Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin; [Verapamil results in decreased activity of ABCB1 protein] which results in increased susceptibility to Paclitaxel; [Verapamil results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; Colchicine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]; Cyclosporine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]; Demecolcine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]; Diazinon promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Diazinon promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]; propiconazole promotes the reaction [Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; propiconazole promotes the reaction [Verapamil results in decreased activity of ABCB1 protein]; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]; Verapamil binds to and affects the activity of ABCB1 protein; Verapamil binds to and results in decreased activity of ABCB1 protein; Verapamil inhibits the reaction [5-Methoxypsoralen results in decreased activity of ABCB1 protein]; Verapamil inhibits the reaction [[5-Methoxypsoralen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]; Verapamil inhibits the reaction [[Methoxsalen results in decreased activity of ABCB1 protein] which results in decreased export of and results in increased abundance of Daunorubicin]; Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in decreased abundance of Quercetin]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of Fluorescent Dyes]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of N-cyano-1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-N'-octyl-2(1H)-isoquinoline-carboximidamide]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of quinidinium]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]; Verapamil inhibits the reaction [Acetaminophen results in increased activity of ABCB1 protein]; Verapamil inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]; Verapamil inhibits the reaction [Methoxsalen results in decreased activity of ABCB1 protein]; Verapamil inhibits the reaction [tangeretin results in increased activity of ABCB1 protein]; Verapamil inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]; Verapamil promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate]; Verapamil promotes the reaction [galangin results in increased activity of ABCB1 protein]; Verapamil promotes the reaction [kaempferol results in increased activity of ABCB1 protein]; Verapamil promotes the reaction [propiconazole inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]]; Verapamil promotes the reaction [propiconazole results in decreased activity of ABCB1 protein]; Verapamil promotes the reaction [Quercetin results in increased activity of ABCB1 protein]; Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]
CTD PMID:2900677 PMID:7083125 PMID:7476894 PMID:8917702 PMID:10527640 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases activity
affects response to substance
EXP
ISO
Verapamil results in decreased activity of ABCB1B protein
ABCB1B protein affects the susceptibility to Verapamil
CTD PMID:12202523 PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity
decreases expression
EXP
ISO
Verapamil results in decreased activity of ABCB4 protein
Verapamil results in decreased expression of ABCB4 mRNA
CTD PMID:12202523 PMID:28437613 PMID:28552422 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects activity
multiple interactions
decreases activity
ISO Verapamil affects the activity of ABCC1 protein
Verapamil inhibits the reaction [ABCC1 protein affects the export of 5-carboxyfluorescein diacetate]; Verapamil inhibits the reaction [ABCC1 protein affects the export of Daunorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Verapamil promotes the reaction [ABCC1 protein affects the export of Glutathione]; Verapamil promotes the reaction [ABCC1 protein affects the transport of Glutathione]; Verapamil promotes the reaction [ABCC1 protein results in increased uptake of Glutathione]
Verapamil results in decreased activity of ABCC1 protein
Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
CTD PMID:7954421 PMID:9334814 PMID:10856430 PMID:11278867 PMID:12485947 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Verapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate] CTD PMID:16636798 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Verapamil inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate] CTD PMID:16636798 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases activity ISO Verapamil results in decreased activity of ABCC6 protein CTD PMID:14667841 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Verapamil inhibits the reaction [[Carbon Tetrachloride co-treated with lard co-treated with Ethanol] results in increased expression of ACTA2 protein] CTD PMID:17223571 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
affects binding
ISO [Quinidine co-treated with Verapamil] inhibits the reaction [ADRA1A protein results in increased abundance of Inositol 1,4,5-Trisphosphate]; Verapamil inhibits the reaction [ADRA1A protein results in increased abundance of Inositol 1,4,5-Trisphosphate]
Verapamil binds to ADRA1A protein
CTD PMID:9570190 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
affects binding
ISO [Quinidine co-treated with Verapamil] inhibits the reaction [ADRA1B protein results in increased abundance of Inositol 1,4,5-Trisphosphate]; Verapamil inhibits the reaction [ADRA1B protein results in increased abundance of Inositol 1,4,5-Trisphosphate]
Verapamil binds to ADRA1B protein
CTD PMID:9570190 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions
affects binding
ISO [Quinidine co-treated with Verapamil] inhibits the reaction [ADRA1D protein results in increased abundance of Inositol 1,4,5-Trisphosphate]; Verapamil inhibits the reaction [ADRA1D protein results in increased abundance of Inositol 1,4,5-Trisphosphate]
Verapamil binds to ADRA1D protein
CTD PMID:9570190 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Adrb1 adrenoceptor beta 1 affects response to substance ISO ADRB1 protein polymorphism affects the susceptibility to Verapamil CTD PMID:22192668 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Verapamil inhibits the reaction [Thioacetamide results in decreased expression of AKT1 mRNA] CTD PMID:30526075 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Verapamil inhibits the reaction [cobaltous chloride results in increased expression of AQP1 protein] CTD PMID:22415096 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Verapamil results in increased expression of BAX protein
[Verapamil co-treated with Temozolomide] results in increased expression of BAX mRNA; Temozolomide promotes the reaction [Verapamil results in increased expression of BAX protein]
CTD PMID:30003979 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [Temozolomide co-treated with Verapamil] results in decreased expression of BCL2 mRNA; [Temozolomide co-treated with Verapamil] results in decreased expression of BCL2 protein; [Verapamil co-treated with gambogic acid] results in decreased expression of BCL2 protein
Verapamil results in decreased expression of BCL2 mRNA; Verapamil results in decreased expression of BCL2 protein
CTD PMID:24373880 PMID:30003979 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
increases response to substance
decreases expression
EXP
ISO
Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1C mRNA]; Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1C protein]
Verapamil inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]
CACNA1C gene polymorphism results in increased susceptibility to Verapamil
Verapamil results in decreased expression of CACNA1C mRNA; Verapamil results in decreased expression of CACNA1C protein
CTD PMID:19791473 PMID:20031608 PMID:27095094 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F multiple interactions ISO Verapamil inhibits the reaction [CACNA1F protein results in increased transport of Barium] CTD PMID:14744918 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions
decreases expression
EXP Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1H mRNA]; Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1H protein]
Verapamil results in decreased expression of CACNA1H mRNA; Verapamil results in decreased expression of CACNA1H protein
CTD PMID:19791473 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions ISO Verapamil inhibits the reaction [[Ionomycin co-treated with Lipopolysaccharides] results in increased expression of CALCA protein]; Verapamil inhibits the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] CTD PMID:20682585 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Verapamil inhibits the reaction [LIF protein results in increased activity of CAMK2A protein]; Verapamil inhibits the reaction [LIF protein results in increased phosphorylation of CAMK2A protein] CTD PMID:11073891 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV multiple interactions EXP Verapamil inhibits the reaction [LIF protein results in increased activity of CAMK4 protein] CTD PMID:11073891 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Verapamil inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; Verapamil inhibits the reaction [Cholesterol analog results in increased activity of CASP1 protein] CTD PMID:28633109 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 multiple interactions ISO [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
EXP
ISO
Verapamil inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
[Doxorubicin co-treated with Verapamil] results in increased activity of CASP3 protein; [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP3 protein; [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP3 protein]; Verapamil inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein]
[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]
Verapamil results in increased expression of CASP3 mRNA
CTD PMID:14527821 PMID:15861398 PMID:18358092 PMID:19631781 PMID:19815060 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein] CTD PMID:15861398 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:24373880 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Verapamil co-treated with gambogic acid] results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:24373880 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein] CTD PMID:9929743 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Verapamil inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein] CTD PMID:34217686 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator affects expression ISO Verapamil affects the expression of CIITA mRNA CTD PMID:25811541 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Clu clusterin affects expression ISO Verapamil affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]
Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]
CTD PMID:27095094 PMID:34217686 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 protein] CTD PMID:34217686 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases localization EXP Verapamil results in decreased localization of CSRP3 protein CTD PMID:19376126 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Verapamil results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Verapamil results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Verapamil results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity ISO Verapamil results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP Verapamil inhibits the reaction [Cyclosporine results in increased expression of CYP2C11 protein] CTD PMID:28899749 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Verapamil results in decreased activity of CYP2C8 protein
Verapamil results in decreased activity of CYP2C29 protein
torsemide inhibits the reaction [Verapamil results in decreased activity of CYP2C8 protein]
CTD PMID:15304522 PMID:18420780
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Verapamil results in decreased activity of CYP2D22 protein; Verapamil results in decreased activity of CYP2D6 protein CTD PMID:18420780 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP Verapamil results in decreased expression of CYP3A18 mRNA CTD PMID:17973928 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
affects metabolic processing
ISO [Verapamil results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; naringin inhibits the reaction [CYP3A4 protein affects the metabolism of Verapamil]; Verapamil inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Verapamil inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Verapamil inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Verapamil inhibits the reaction [CYP3A4 protein results in increased metabolism of Testosterone]; Verapamil inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
Verapamil results in decreased activity of CYP3A4 protein
CTD PMID:15286053 PMID:15689501 PMID:15692829 PMID:15860655 PMID:16013069 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression
decreases activity
EXP
ISO
Verapamil results in decreased expression of CYP3A9 mRNA
Verapamil results in decreased activity of CYP3A5 protein
CTD PMID:15689501 PMID:17973928 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Verapamil co-treated with gambogic acid] results in increased expression of DDIT3 protein CTD PMID:24373880 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation
ISO Verapamil inhibits the reaction [bisphenol A affects the localization of DNM1L protein]
Verapamil results in increased phosphorylation of DNM1L protein
CTD PMID:31830493 PMID:34023961 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO Verapamil inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9533112 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO Verapamil inhibits the reaction [Raclopride binds to DRD2 protein] CTD PMID:9533112 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Verapamil inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] CTD PMID:34217686 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Verapamil results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein] CTD PMID:27095094 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Verapamil affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Verapamil affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gc GC, vitamin D binding protein affects expression EXP Verapamil affects the expression of GC protein CTD PMID:23533533 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
EXP Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]; Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]
Verapamil results in increased expression of GFAP mRNA
CTD PMID:21863293 PMID:21879721 PMID:22954530 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Verapamil inhibits the reaction [Thioacetamide results in increased expression of GPT protein] CTD PMID:30526075 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsn gelsolin affects expression EXP Verapamil affects the expression of GSN protein CTD PMID:23533533 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO Verapamil promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA] CTD PMID:27095094 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Verapamil results in increased expression of HMOX1 protein
Verapamil inhibits the reaction [Thioacetamide results in decreased expression of HMOX1 mRNA]
CTD PMID:21525764 PMID:30526075 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions EXP Verapamil inhibits the reaction [Glucose results in increased expression of IAPP mRNA] CTD PMID:9142872 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Verapamil inhibits the reaction [Particulate Matter results in increased expression of IL1A mRNA] CTD PMID:15613243 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Verapamil inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:20682585 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Verapamil inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:194,786,500...194,798,575
Ensembl chr 2:194,786,500...194,798,575
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 decreases activity
multiple interactions
ISO Verapamil results in decreased activity of KCNA3 protein
[Verapamil results in decreased activity of KCNA3 protein] which results in decreased import of Thallium
CTD PMID:21362439 NCBI chr 2:194,632,360...194,633,937
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 decreases activity ISO Verapamil results in decreased activity of KCND3 protein CTD PMID:11181069 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO [Verapamil results in decreased activity of KCNH2 protein] which results in decreased import of Thallium; Verapamil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:15671647 PMID:19583963 PMID:21158687 PMID:21362439 PMID:24052561 More... NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 affects response to substance ISO KCNMB1 gene SNP affects the susceptibility to Verapamil CTD PMID:17700361 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions EXP Verapamil inhibits the reaction [LIF protein results in increased activity of CAMK2A protein]; Verapamil inhibits the reaction [LIF protein results in increased activity of CAMK4 protein]; Verapamil inhibits the reaction [LIF protein results in increased phosphorylation of CAMK2A protein] CTD PMID:11073891 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Verapamil inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK1 protein] CTD PMID:15456914 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Verapamil inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK3 protein] CTD PMID:15456914 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP Verapamil promotes the reaction [ferrous sulfate results in increased expression of MMP13 protein] CTD PMID:27095094 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Verapamil promotes the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:17015168 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mybpc3 myosin binding protein C3 affects response to substance ISO MYBPC3 protein affects the susceptibility to Verapamil CTD PMID:23896226 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
decreases expression
ISO Dexamethasone inhibits the reaction [Verapamil results in decreased expression of MYH7 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Verapamil results in decreased expression of MYH7 mRNA]] CTD PMID:19596060 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myl2 myosin light chain 2 multiple interactions
decreases expression
ISO [Verapamil co-treated with Doxorubicin] results in decreased expression of MYL2 mRNA; Dexamethasone inhibits the reaction [[Verapamil co-treated with Doxorubicin] results in decreased expression of MYL2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [[Verapamil co-treated with Doxorubicin] results in decreased expression of MYL2 mRNA]]
Verapamil results in decreased expression of MYL2 mRNA
CTD PMID:19596060 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein]; Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
ISO
EXP
Verapamil affects the localization of NFE2L2 protein
Verapamil inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 mRNA]
CTD PMID:21525764 PMID:30526075 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nppa natriuretic peptide A multiple interactions
increases expression
affects secretion
ISO [Cilazapril co-treated with Verapamil] affects the secretion of NPPA protein
Verapamil results in increased expression of NPPA protein
Verapamil affects the secretion of NPPA protein
CTD PMID:1457087 PMID:11996326 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions
decreases expression
ISO Verapamil promotes the reaction [Cyclic AMP results in decreased expression of NR0B1 mRNA]
Verapamil results in decreased expression of NR0B1 mRNA
CTD PMID:19822634 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO Verapamil results in increased activity of NR1I2 protein
[Verapamil results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Verapamil promotes the reaction [Dexamethasone results in increased activity of NR3C1 protein] CTD PMID:12871829 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Verapamil inhibits the reaction [PARP1 gene mutant form results in decreased uptake of Doxorubicin]
[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]
CTD PMID:15861398 PMID:24373880 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pf4 platelet factor 4 decreases expression ISO Verapamil results in decreased expression of PF4 protein CTD PMID:2962587 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Polr1h RNA polymerase I subunit H multiple interactions ISO Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Doxorubicin]; Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [POLR1H protein results in increased secretion of Doxorubicin] CTD PMID:14726695 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854
JBrowse link
G Ppbp pro-platelet basic protein decreases expression ISO Verapamil results in decreased expression of PPBP protein CTD PMID:2962587 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta multiple interactions ISO Verapamil inhibits the reaction [bisphenol F results in increased expression of PPP3CB protein] CTD PMID:34023961 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Prl prolactin increases secretion
increases expression
multiple interactions
ISO Verapamil results in increased secretion of PRL protein
Verapamil results in increased expression of PRL protein
Verapamil inhibits the reaction [Sulpiride results in increased secretion of PRL protein]; Verapamil promotes the reaction [TRH protein results in increased secretion of PRL protein]
CTD PMID:7851873 PMID:8845563 PMID:8977754 PMID:20595935 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ret ret proto-oncogene affects expression ISO Verapamil affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of SLC11A2 protein] CTD PMID:27095094 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Verapamil inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Verapamil inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Verapamil inhibits the reaction [SLC22A1 protein results in increased import of Tetraethylammonium]; Verapamil inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC22A1 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 PMID:25466967 PMID:25862123 PMID:27450509 PMID:27989701 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO
EXP
Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
Verapamil inhibits the reaction [SLC22A2 protein results in increased uptake of mepiquat]
CTD PMID:21599003 PMID:33639197 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Verapamil inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC22A3 protein results in increased uptake of Metformin] CTD PMID:21641380 PMID:21697722 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Verapamil inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases activity ISO Verapamil results in decreased activity of SLC22A5 protein CTD PMID:15486076 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions
decreases activity
ISO Verapamil inhibits the reaction [SLC47A1 protein results in increased import of Tetraethylammonium]; Verapamil inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC47A1 protein results in increased uptake of Tetraethylammonium]
Verapamil results in decreased activity of SLC47A1 protein
CTD PMID:22419765 PMID:27450509 PMID:27989701 PMID:31364238 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions
decreases activity
ISO Verapamil inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Verapamil inhibits the reaction [SLC47A2 protein results in increased uptake of Tetraethylammonium]
Verapamil results in decreased activity of SLC47A2 protein
CTD PMID:22419765 PMID:27989701 PMID:28629854 PMID:31364238 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions ISO Verapamil inhibits the reaction [SLCO1A2 protein results in increased uptake of Quercetin] CTD PMID:24947867 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO Verapamil inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein] CTD PMID:34217686 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Verapamil inhibits the reaction [Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD1 protein]] CTD PMID:17015168 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Verapamil inhibits the reaction [Dexamethasone inhibits the reaction [Paraquat results in increased activity of SOD2 protein]] CTD PMID:17015168 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA]; Verapamil promotes the reaction [Cyclic AMP results in increased expression of STAR protein] CTD PMID:19822634 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]; Verapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein] CTD PMID:19299911 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
Verapamil inhibits the reaction [[Carbon Tetrachloride co-treated with lard co-treated with Ethanol] results in increased expression of TGFB1 protein]
Verapamil inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 protein]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Verapamil inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Verapamil inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]
CTD PMID:17223571 PMID:34217686 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression
multiple interactions
ISO
EXP
Verapamil affects the expression of TIMP1 protein
Verapamil inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]
CTD PMID:12388792 PMID:27095094 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Verapamil inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]
Verapamil affects the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Verapamil inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]
CTD PMID:15613243 PMID:17092623 PMID:17129690 PMID:17369293 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions ISO Verapamil inhibits the reaction [TRH protein results in increased secretion of TSHB protein]; Verapamil promotes the reaction [TRH protein results in increased secretion of PRL protein] CTD PMID:7851873 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO Verapamil inhibits the reaction [TRH protein results in increased secretion of TSHB protein] CTD PMID:7851873 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Vim vimentin multiple interactions EXP
ISO
Verapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein]; Verapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein]
Verapamil inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]
CTD PMID:21863293 PMID:21879721 PMID:34217686 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
benzoylaconine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of benzoylaconine
[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylaconine
CTD PMID:23200901 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylaconine CTD PMID:23200901 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
benzoylhypaconine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport
ISO [Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine
ABCB1 protein results in increased transport of benzoylhypaconine
CTD PMID:23200901 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylhypaconine CTD PMID:23200901 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of benzoylhypaconine CTD PMID:23200901 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
benzoylmesaconine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of benzoylmesaconine
[Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylmesaconine
CTD PMID:23200901 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylmesaconine CTD PMID:23200901 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
copanlisib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO copanlisib results in decreased phosphorylation of AKT1 protein CTD PMID:31445927 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Fas Fas cell surface death receptor affects response to substance ISO copanlisib affects the susceptibility to FAS protein CTD PMID:31445927 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Tnf tumor necrosis factor increases response to substance ISO copanlisib results in increased susceptibility to TNF protein CTD PMID:31445927 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
deguelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO deguelin results in increased expression of ABCC4 mRNA CTD PMID:33512557 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression ISO deguelin results in decreased expression of ABCC5 mRNA CTD PMID:33512557 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 decreases expression ISO deguelin results in decreased expression of ABCF1 mRNA CTD PMID:33512557 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO deguelin results in decreased expression of ADAM12 mRNA CTD PMID:33512557 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 decreases expression ISO deguelin results in decreased expression of ADAM8 mRNA CTD PMID:33512557 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adm adrenomedullin multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ADM mRNA] CTD PMID:22745725 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ado 2-aminoethanethiol dioxygenase increases expression ISO deguelin results in increased expression of ADO mRNA CTD PMID:33512557 NCBI chr20:21,044,815...21,045,983
Ensembl chr20:21,044,555...21,049,235
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO deguelin results in increased expression of AEN mRNA CTD PMID:33512557 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO deguelin results in increased expression of and affects the localization of AIFM1 protein CTD PMID:26592500 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akap8l A-kinase anchoring protein 8 like increases expression ISO deguelin results in increased expression of AKAP8L mRNA CTD PMID:33512557 NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases expression ISO deguelin results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO deguelin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases expression ISO deguelin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
affects phosphorylation
increases phosphorylation
multiple interactions
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of AKT1 protein; deguelin results in decreased expression of AKT1 mRNA; deguelin results in decreased expression of AKT1 protein
deguelin affects the phosphorylation of AKT1 protein
deguelin results in increased phosphorylation of AKT1 protein
deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]
deguelin results in decreased phosphorylation of AKT1 protein
CTD PMID:16288123 PMID:17015749 PMID:18593368 PMID:19139008 PMID:19336726 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO deguelin results in decreased expression of ALDH7A1 mRNA CTD PMID:33512557 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO deguelin results in decreased expression of ALDH8A1 mRNA CTD PMID:33512557 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Amdhd2 amidohydrolase domain containing 2 decreases expression ISO deguelin results in decreased expression of AMDHD2 mRNA CTD PMID:33512557 NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
JBrowse link
G Amer1 APC membrane recruitment protein 1 decreases expression ISO deguelin results in decreased expression of AMER1 mRNA CTD PMID:33512557 NCBI chr  X:60,300,595...60,316,480
Ensembl chr  X:60,295,751...60,316,440
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO deguelin results in decreased expression of ANGPTL2 mRNA CTD PMID:33512557 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] CTD PMID:22745725 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anln anillin, actin binding protein increases expression ISO deguelin results in increased expression of ANLN mRNA CTD PMID:33512557 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Ano10 anoctamin 10 decreases expression ISO deguelin results in decreased expression of ANO10 mRNA CTD PMID:33512557 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670
JBrowse link
G Anxa7 annexin A7 increases expression ISO deguelin results in increased expression of ANXA7 mRNA CTD PMID:33512557 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 decreases expression ISO deguelin results in decreased expression of AP2M1 mRNA CTD PMID:33512557 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 decreases expression ISO deguelin results in decreased expression of AP3M1 mRNA CTD PMID:33512557 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO deguelin results in decreased expression of APLP1 mRNA CTD PMID:33512557 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
JBrowse link
G Ar androgen receptor multiple interactions ISO deguelin results in decreased expression of and affects the localization of AR protein CTD PMID:27255535 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO deguelin results in increased expression of ARHGAP8 mRNA CTD PMID:33512557 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO deguelin results in increased expression of ARHGAP9 mRNA CTD PMID:33512557 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO deguelin results in increased expression of ARHGEF2 mRNA CTD PMID:33512557 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arid4a AT-rich interaction domain 4A decreases expression ISO deguelin results in decreased expression of ARID4A mRNA CTD PMID:33512557 NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 increases expression ISO deguelin results in increased expression of ARIH2 mRNA CTD PMID:33512557 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression ISO deguelin results in increased expression of ARL1 mRNA CTD PMID:33512557 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO deguelin results in increased expression of ARNT mRNA CTD PMID:33512557 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO deguelin results in decreased expression of ARRDC4 mRNA CTD PMID:33512557 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Arsg arylsulfatase G increases expression ISO deguelin results in increased expression of ARSG mRNA CTD PMID:33512557 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO deguelin results in increased expression of ASCC3 mRNA CTD PMID:33512557 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO deguelin results in increased expression of ASCL1 mRNA CTD PMID:33512557 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO deguelin results in decreased expression of ASF1B mRNA CTD PMID:33512557 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO deguelin results in decreased expression of ASGR1 mRNA CTD PMID:33512557 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO deguelin results in increased expression of ASNS mRNA CTD PMID:33512557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO deguelin results in increased expression of ASS1 mRNA CTD PMID:33512557 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO deguelin results in increased expression of ATF4 mRNA CTD PMID:33512557 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO deguelin results in increased expression of ATF5 mRNA CTD PMID:33512557 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atg3 autophagy related 3 increases expression ISO deguelin results in increased expression of ATG3 mRNA CTD PMID:33512557 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression ISO deguelin results in increased expression of ATIC mRNA CTD PMID:33512557 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO deguelin results in decreased expression of ATM mRNA CTD PMID:22227970 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atmin ATM interactor decreases expression ISO deguelin results in decreased expression of ATMIN mRNA CTD PMID:33512557 NCBI chr19:44,996,506...45,013,606
Ensembl chr19:44,996,356...45,013,605
JBrowse link
G Atp11b ATPase phospholipid transporting 11B (putative) decreases expression ISO deguelin results in decreased expression of ATP11B mRNA CTD PMID:33512557 NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
JBrowse link
G Atp11c ATPase phospholipid transporting 11C decreases expression ISO deguelin results in decreased expression of ATP11C mRNA CTD PMID:33512557 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 decreases expression ISO deguelin results in decreased expression of ATP6V0E1 mRNA CTD PMID:33512557 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO deguelin results in decreased expression of ATP6V1B2 mRNA CTD PMID:33512557 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO deguelin results in decreased expression of ATR mRNA CTD PMID:22227970 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor increases expression ISO deguelin results in increased expression of ATRAID mRNA CTD PMID:33512557 NCBI chr 6:25,315,236...25,319,804 JBrowse link
G Aurka aurora kinase A increases expression ISO deguelin results in increased expression of AURKA mRNA CTD PMID:33512557 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G B2m beta-2 microglobulin increases expression ISO deguelin results in increased expression of B2M mRNA CTD PMID:33512557 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 decreases expression ISO deguelin results in decreased expression of B3GALT6 mRNA CTD PMID:33512557 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338
JBrowse link
G B3gat1 beta-1,3-glucuronyltransferase 1 decreases expression ISO deguelin results in decreased expression of B3GAT1 mRNA CTD PMID:33512557 NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO deguelin results in increased expression of BAG3 mRNA CTD PMID:33512557 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO deguelin results in increased expression of BAK1 protein CTD PMID:26592500 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO deguelin results in increased expression of BAX mRNA; deguelin results in increased expression of BAX protein CTD PMID:26592500 PMID:29512685 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO deguelin results in increased expression of BCAT1 mRNA CTD PMID:33512557 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO deguelin results in decreased expression of BCL2 mRNA; deguelin results in decreased expression of BCL2 protein
deguelin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]
CTD PMID:19365708 PMID:22623043 PMID:26592500 PMID:29512685 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]
deguelin results in decreased expression of BCL2L1 mRNA; deguelin results in decreased expression of BCL2L1 protein
CTD PMID:19365708 PMID:21472727 PMID:22623043 PMID:26592500 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 decreases expression ISO deguelin results in decreased expression of BCL2L11 mRNA CTD PMID:33512557 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l13 Bcl2-like 13 decreases expression ISO deguelin results in decreased expression of BCL2L13 mRNA CTD PMID:33512557 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression ISO deguelin results in decreased expression of BCL2L2 mRNA CTD PMID:33512557 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO deguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]
deguelin results in increased expression of BDNF mRNA
CTD PMID:17209049 PMID:33512557 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO deguelin results in decreased expression of BID mRNA CTD PMID:33512557 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
decreases expression
ISO deguelin inhibits the reaction [docetaxel results in increased expression of BIRC5 protein]; deguelin inhibits the reaction [Doxorubicin results in increased expression of BIRC5 protein]
deguelin results in increased expression of BIRC5 mRNA
deguelin results in decreased expression of BIRC5 protein
CTD PMID:17035597 PMID:18593368 PMID:21472727 PMID:33512557 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 increases expression ISO deguelin results in increased expression of BLOC1S2 mRNA CTD PMID:33512557 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO deguelin results in decreased expression of BMF mRNA CTD PMID:33512557 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO deguelin results in increased expression of BNIP3L mRNA CTD PMID:33512557 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bphl biphenyl hydrolase like decreases expression ISO deguelin results in decreased expression of BPHL mRNA CTD PMID:33512557 NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO deguelin results in decreased expression of BRCA1 mRNA CTD PMID:22227970 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brd2 bromodomain containing 2 increases expression ISO deguelin results in increased expression of BRD2 mRNA CTD PMID:33512557 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Brd3 bromodomain containing 3 decreases expression ISO deguelin results in decreased expression of BRD3 mRNA CTD PMID:33512557 NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
JBrowse link
G Brms1l BRMS1 like transcriptional repressor decreases expression ISO deguelin results in decreased expression of BRMS1L mRNA CTD PMID:33512557 NCBI chr 6:73,266,673...73,300,631
Ensembl chr 6:73,266,691...73,300,631
JBrowse link
G Bsg basigin (Ok blood group) increases expression ISO deguelin results in increased expression of BSG mRNA CTD PMID:33512557 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO deguelin results in increased expression of BTG3 mRNA CTD PMID:33512557 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 decreases expression ISO deguelin results in decreased expression of BZW1 mRNA CTD PMID:33512557 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C1s complement C1s decreases expression ISO deguelin results in decreased expression of C1S mRNA CTD PMID:33512557 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 decreases expression ISO deguelin results in decreased expression of C2CD5 mRNA CTD PMID:33512557 NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 decreases expression ISO deguelin results in decreased expression of CALCOCO1 mRNA CTD PMID:33512557 NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO deguelin results in decreased expression of CALM1 mRNA CTD PMID:33512557 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO deguelin results in decreased expression of CALM3 mRNA CTD PMID:33512557 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Calr calreticulin decreases expression ISO deguelin results in decreased expression of CALR mRNA CTD PMID:33512557 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Calu calumenin decreases expression ISO deguelin results in decreased expression of CALU mRNA CTD PMID:33512557 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO deguelin results in decreased expression of CAMK2B mRNA CTD PMID:33512557 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cant1 calcium activated nucleotidase 1 decreases expression ISO deguelin results in decreased expression of CANT1 mRNA CTD PMID:33512557 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Canx calnexin increases expression ISO deguelin results in increased expression of CANX mRNA CTD PMID:33512557 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capn1 calpain 1 decreases expression ISO deguelin results in decreased expression of CAPN1 mRNA CTD PMID:33512557 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Caps calcyphosine decreases expression ISO deguelin results in decreased expression of CAPS mRNA CTD PMID:33512557 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
JBrowse link
G Car9 carbonic anhydrase 9 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA] CTD PMID:22745725 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO deguelin results in decreased expression of CARMIL1 mRNA CTD PMID:33512557 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO deguelin results in increased expression of CARS1 mRNA CTD PMID:33512557 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases expression ISO deguelin results in increased expression of CASK mRNA CTD PMID:33512557 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
ISO deguelin results in increased cleavage of CASP3 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein
deguelin results in increased activity of CASP3 protein
CTD PMID:18593368 PMID:19336726 PMID:22623043 PMID:22986522 PMID:25242579 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein CTD PMID:25242579 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression ISO deguelin metabolite results in increased expression of CASP7 protein modified form; deguelin results in increased expression of CASP7 protein modified form CTD PMID:19139008 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein CTD PMID:25242579 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cast calpastatin decreases expression ISO deguelin results in decreased expression of CAST mRNA CTD PMID:33512557 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO deguelin results in decreased expression of CBLB mRNA CTD PMID:33512557 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cbx4 chromobox 4 increases expression ISO deguelin results in increased expression of CBX4 mRNA CTD PMID:33512557 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP deguelin promotes the reaction [Oxygen deficiency results in increased expression of CCL2 mRNA] CTD PMID:22745725 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:28529457 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression ISO deguelin results in decreased expression of CCL15 mRNA CTD PMID:33512557 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccna2 cyclin A2 increases expression ISO deguelin results in increased expression of CCNA2 mRNA CTD PMID:33512557 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO deguelin results in increased expression of CCNB1 mRNA CTD PMID:33512557 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO deguelin results in increased expression of CCNB2 mRNA CTD PMID:33512557 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of CCND1 protein] CTD PMID:15960896 PMID:17015749 PMID:19861542 PMID:21472727 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO deguelin results in decreased expression of CCND3 mRNA CTD PMID:33512557 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO deguelin results in decreased expression of CCNE1 mRNA CTD PMID:29512685 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO deguelin results in decreased expression of CCNE2 mRNA CTD PMID:33512557 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng1 cyclin G1 increases expression ISO deguelin results in increased expression of CCNG1 mRNA CTD PMID:33512557 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccnh cyclin H increases expression ISO deguelin results in increased expression of CCNH mRNA CTD PMID:33512557 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression ISO deguelin results in increased expression of CCT6A mRNA CTD PMID:33512557 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein CTD PMID:25242579 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd163 CD163 molecule multiple interactions EXP [deguelin co-treated with Oxygen deficiency] results in increased expression of CD163 mRNA CTD PMID:22745725 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd19 CD19 molecule decreases expression ISO deguelin results in decreased expression of CD19 mRNA CTD PMID:33512557 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Cd24 CD24 molecule decreases expression ISO deguelin results in decreased expression of CD24 mRNA CTD PMID:33512557 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO deguelin results in decreased expression of CD44 mRNA; deguelin results in decreased expression of CD44 protein CTD PMID:26884827 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO deguelin results in decreased expression of CDC45 mRNA CTD PMID:33512557 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO deguelin results in decreased expression of CDC6 mRNA CTD PMID:34642769 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh1 cadherin 1 multiple interactions
affects localization
increases expression
ISO deguelin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein]
deguelin affects the localization of CDH1 protein
deguelin results in increased expression of CDH1 mRNA; deguelin results in increased expression of CDH1 protein
CTD PMID:22986522 PMID:28509438 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh10 cadherin 10 decreases expression ISO deguelin results in decreased expression of CDH10 mRNA CTD PMID:33512557 NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO deguelin results in decreased expression of CDH2 mRNA; deguelin results in decreased expression of CDH2 protein CTD PMID:22986522 PMID:33512557 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh3 cadherin 3 increases expression ISO deguelin results in increased expression of CDH3 mRNA CTD PMID:19861542 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdh7 cadherin 7 increases expression ISO deguelin results in increased expression of CDH7 mRNA CTD PMID:19861542 NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
JBrowse link
G Cdh9 cadherin 9 increases expression ISO deguelin results in increased expression of CDH9 mRNA CTD PMID:19861542 NCBI chr 2:66,280,422...66,367,121
Ensembl chr 2:66,228,117...66,367,121
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO deguelin results in increased expression of CDK1 mRNA CTD PMID:33512557 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO deguelin metabolite results in decreased expression of CDK4 protein; deguelin results in decreased expression of CDK4 protein CTD PMID:19139008 PMID:19336726 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO deguelin results in decreased expression of CDK5 mRNA CTD PMID:33512557 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 decreases expression ISO deguelin results in decreased expression of CDK5R1 mRNA CTD PMID:33512557 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO deguelin results in increased expression of CDK6 mRNA CTD PMID:33512557 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; deguelin metabolite results in decreased expression of CDKN1A protein; deguelin results in decreased expression of CDKN1A protein
deguelin results in increased expression of CDKN1A mRNA
CTD PMID:19139008 PMID:25242579 PMID:29512685 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO deguelin results in increased expression of CDKN1B mRNA CTD PMID:33512557 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO deguelin results in increased expression of CDKN3 mRNA CTD PMID:33512557 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO deguelin results in increased expression of CDT1 mRNA CTD PMID:33512557 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein CTD PMID:25242579 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO deguelin results in increased expression of CEBPB mRNA CTD PMID:33512557 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cel carboxyl ester lipase decreases expression ISO deguelin results in decreased expression of CEL mRNA CTD PMID:33512557 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO deguelin results in decreased expression of CEMIP2 mRNA CTD PMID:33512557 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Cenpf centromere protein F increases expression ISO deguelin results in increased expression of CENPF mRNA CTD PMID:33512557 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpk centromere protein K decreases expression ISO deguelin results in decreased expression of CENPK mRNA CTD PMID:33512557 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Cenpu centromere protein U increases expression ISO deguelin results in increased expression of CENPU mRNA CTD PMID:33512557 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
JBrowse link
G Cep55 centrosomal protein 55 increases expression ISO deguelin results in increased expression of CEP55 mRNA CTD PMID:33512557 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Cetn3 centrin 3 decreases expression ISO deguelin results in decreased expression of CETN3 mRNA CTD PMID:33512557 NCBI chr 2:12,089,025...12,101,828
Ensembl chr 2:12,089,226...12,101,828
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]
deguelin results in decreased expression of CFLAR mRNA
CTD PMID:22623043 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO deguelin results in increased expression of CHAC1 mRNA CTD PMID:33512557 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO deguelin results in increased expression of CHEK1 mRNA CTD PMID:33512557 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chka choline kinase alpha increases expression ISO deguelin results in increased expression of CHKA mRNA CTD PMID:33512557 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chn1 chimerin 1 increases expression ISO deguelin results in increased expression of CHN1 mRNA CTD PMID:33512557 NCBI chr 3:58,509,822...58,676,774
Ensembl chr 3:58,510,536...58,676,490
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO deguelin results in decreased expression of CHRNA4 mRNA CTD PMID:33512557 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression ISO deguelin results in decreased expression of CHRNB2 mRNA CTD PMID:33512557 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression ISO deguelin results in increased expression of CHUK mRNA CTD PMID:33512557 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression ISO deguelin results in increased expression of CISD1 mRNA CTD PMID:33512557 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression ISO deguelin results in increased expression of CKS1B mRNA CTD PMID:33512557 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO deguelin results in increased expression of CKS2 mRNA CTD PMID:33512557 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn2 claudin 2 increases expression ISO deguelin results in increased expression of CLDN2 mRNA CTD PMID:19861542 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn5 claudin 5 increases expression
decreases expression
ISO deguelin results in increased expression of CLDN5 mRNA
deguelin results in decreased expression of CLDN5 mRNA
CTD PMID:19861542 PMID:33512557 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO deguelin results in increased expression of CLIC4 mRNA CTD PMID:33512557 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO deguelin results in increased expression of CLK1 mRNA CTD PMID:33512557 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO deguelin results in increased expression of CLPX mRNA CTD PMID:33512557 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Cltc clathrin heavy chain increases expression ISO deguelin results in increased expression of CLTC mRNA CTD PMID:33512557 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cmss1 cms1 ribosomal small subunit homolog increases expression ISO deguelin results in increased expression of CMSS1 mRNA CTD PMID:33512557 NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624
JBrowse link
G Cntn1 contactin 1 decreases expression ISO deguelin results in decreased expression of CNTN1 mRNA CTD PMID:33512557 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 increases expression ISO deguelin results in increased expression of COA6 mRNA CTD PMID:33512557 NCBI chr19:54,395,682...54,398,918
Ensembl chr19:54,395,742...54,399,407
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO deguelin results in increased expression of COL4A2 mRNA CTD PMID:33512557 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO deguelin results in increased expression of COMT mRNA CTD PMID:33512557 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cops5 COP9 signalosome subunit 5 decreases expression ISO deguelin results in decreased expression of COPS5 mRNA CTD PMID:33512557 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731
JBrowse link
G Coro1a coronin 1A decreases expression ISO deguelin results in decreased expression of CORO1A mRNA CTD PMID:33512557 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Cpne3 copine 3 decreases expression ISO deguelin results in decreased expression of CPNE3 mRNA CTD PMID:33512557 NCBI chr 5:33,014,658...33,064,004
Ensembl chr 5:33,016,307...33,063,934
JBrowse link
G Cramp1 cramped chromatin regulator homolog 1 decreases expression ISO deguelin results in decreased expression of CRAMP1 mRNA CTD PMID:33512557 NCBI chr10:13,983,781...14,032,409
Ensembl chr10:13,983,866...14,032,392
JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO deguelin results in increased expression of CREBRF mRNA CTD PMID:33512557 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression ISO deguelin results in decreased expression of CRK mRNA CTD PMID:33512557 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein increases expression ISO deguelin results in increased expression of CRKL mRNA CTD PMID:33512557 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases expression ISO deguelin results in decreased expression of CSNK1A1 mRNA CTD PMID:33512557 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO deguelin results in increased expression of CSRNP1 mRNA CTD PMID:33512557 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO deguelin results in increased expression of CTH mRNA CTD PMID:33512557 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO deguelin results in increased expression of CTNNAL1 mRNA CTD PMID:33512557 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
increases degradation
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein]
deguelin results in decreased expression of CTNNB1 mRNA; deguelin results in decreased expression of CTNNB1 protein
CTD PMID:21472727 PMID:22986522 PMID:33512557 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 decreases expression ISO deguelin results in decreased expression of CTNND1 mRNA CTD PMID:33512557 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO deguelin results in decreased expression of CTPS1 mRNA CTD PMID:33512557 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D increases expression ISO deguelin results in increased expression of CTSD mRNA CTD PMID:33512557 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctss cathepsin S decreases expression ISO deguelin results in decreased expression of CTSS mRNA CTD PMID:33512557 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cttn cortactin decreases expression ISO deguelin results in decreased expression of CTTN mRNA CTD PMID:33512557 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CXCR4 mRNA]
deguelin results in decreased expression of CXCR4 mRNA
CTD PMID:22745725 PMID:33512557 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO deguelin results in decreased expression of CYCS mRNA CTD PMID:33512557 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO deguelin inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA] CTD PMID:19961161 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO deguelin results in decreased expression of CYP26B1 mRNA CTD PMID:33512557 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression ISO deguelin affects the expression of CYP3A5 mRNA CTD PMID:34642769 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO deguelin results in decreased expression of DAAM1 mRNA CTD PMID:33512557 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
JBrowse link
G Daxx death-domain associated protein decreases expression ISO deguelin results in decreased expression of DAXX mRNA CTD PMID:33512557 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO deguelin results in increased expression of DBF4 mRNA CTD PMID:33512557 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Dbndd2 dysbindin domain containing 2 decreases expression ISO deguelin results in decreased expression of DBNDD2 mRNA CTD PMID:33512557 NCBI chr 3:153,193,213...153,220,651
Ensembl chr 3:153,191,090...153,220,651
JBrowse link
G Dctd dCMP deaminase increases expression ISO deguelin results in increased expression of DCTD mRNA CTD PMID:33512557 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446
JBrowse link
G Dcx doublecortin decreases expression ISO deguelin results in decreased expression of DCX mRNA CTD PMID:33512557 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO deguelin results in decreased expression of DDC mRNA CTD PMID:33512557 PMID:34642769 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO deguelin results in increased expression of DDIT3 mRNA CTD PMID:33512557 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dennd3 DENN domain containing 3 decreases expression ISO deguelin results in decreased expression of DENND3 mRNA CTD PMID:33512557 NCBI chr 7:105,415,870...105,473,583
Ensembl chr 7:105,415,677...105,473,592
JBrowse link
G Depdc1b DEP domain containing 1B increases expression ISO deguelin results in increased expression of DEPDC1B mRNA CTD PMID:33512557 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO deguelin results in decreased expression of DFFB mRNA CTD PMID:33512557 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit decreases expression ISO deguelin results in decreased expression of DHDDS mRNA CTD PMID:33512557 NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression ISO deguelin results in increased expression of DHRS7 mRNA CTD PMID:33512557 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression ISO deguelin results in increased expression of DHX15 mRNA CTD PMID:33512557 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 decreases expression ISO deguelin results in decreased expression of DKK2 mRNA CTD PMID:19861542 NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO deguelin results in increased expression of DKK4 mRNA CTD PMID:19861542 NCBI chr16:69,402,989...69,406,580
Ensembl chr16:69,402,989...69,406,580
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO deguelin results in increased expression of DLAT mRNA CTD PMID:33512557 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO deguelin results in increased expression of DLGAP5 mRNA CTD PMID:33512557 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dll4 delta like canonical Notch ligand 4 decreases expression ISO deguelin results in decreased expression of DLL4 mRNA CTD PMID:33512557 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO deguelin results in increased expression of DNAJB1 mRNA CTD PMID:33512557 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO deguelin results in increased expression of DNAJB9 mRNA CTD PMID:33512557 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression ISO deguelin results in increased expression of DNAJC15 mRNA CTD PMID:33512557 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
JBrowse link
G Dnm1 dynamin 1 decreases expression ISO deguelin results in decreased expression of DNM1 mRNA CTD PMID:33512557 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnm1l dynamin 1-like increases expression ISO deguelin results in increased expression of DNM1L mRNA CTD PMID:33512557 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dpp10 dipeptidyl peptidase like 10 increases expression ISO deguelin results in increased expression of DPP10 mRNA CTD PMID:33512557 NCBI chr13:34,584,420...36,269,619
Ensembl chr13:34,595,868...36,269,292
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO deguelin results in decreased expression of DRD2 mRNA CTD PMID:33512557 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dusp14 dual specificity phosphatase 14 increases expression ISO deguelin results in increased expression of DUSP14 mRNA CTD PMID:33512557 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
JBrowse link
G Dusp3 dual specificity phosphatase 3 increases expression ISO deguelin results in increased expression of DUSP3 mRNA CTD PMID:33512557 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO deguelin results in increased expression of DUSP4 mRNA CTD PMID:33512557 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 decreases expression ISO deguelin results in decreased expression of DYRK3 mRNA CTD PMID:33512557 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO deguelin results in decreased expression of E2F1 mRNA CTD PMID:33512557 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO deguelin results in decreased expression of EBF1 mRNA CTD PMID:33512557 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 decreases expression ISO deguelin results in decreased expression of EBNA1BP2 mRNA CTD PMID:33512557 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
JBrowse link
G Eea1 early endosome antigen 1 increases expression ISO deguelin results in increased expression of EEA1 mRNA CTD PMID:33512557 NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO deguelin results in increased expression of EEF1B2 mRNA CTD PMID:33512557 NCBI chr 9:64,580,009...64,582,737
Ensembl chr 9:64,579,893...64,582,737
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO deguelin metabolite results in decreased expression of EGFR protein; deguelin results in decreased expression of EGFR protein CTD PMID:19139008 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of EGLN3 mRNA] CTD PMID:22745725 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO deguelin results in increased expression of EIF1 mRNA CTD PMID:33512557 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO deguelin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25322282 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta increases expression ISO deguelin results in increased expression of EIF2S2 mRNA CTD PMID:33512557 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B increases expression ISO deguelin results in increased expression of EIF4B mRNA CTD PMID:33512557 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
increases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of EIF4EBP1 protein modified form; deguelin results in decreased expression of EIF4EBP1 protein modified form
deguelin results in increased expression of EIF4EBP1 mRNA
deguelin results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:19139008 PMID:27255535 PMID:33512557 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 decreases expression ISO deguelin results in decreased expression of ELAVL1 mRNA CTD PMID:33512557 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Elmod1 ELMO domain containing 1 decreases expression ISO deguelin results in decreased expression of ELMOD1 mRNA CTD PMID:33512557 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO deguelin results in decreased expression of ELP1 mRNA CTD PMID:33512557 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Endog endonuclease G decreases expression ISO deguelin results in decreased expression of ENDOG mRNA CTD PMID:33512557 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Eno2 enolase 2 decreases secretion
decreases expression
ISO deguelin results in decreased secretion of ENO2 protein
deguelin results in decreased expression of ENO2 mRNA
CTD PMID:26884827 PMID:33512557 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein] CTD PMID:27899277 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO deguelin results in decreased expression of EP300 mRNA CTD PMID:33512557 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephb2 Eph receptor B2 decreases expression ISO deguelin results in decreased expression of EPHB2 mRNA CTD PMID:33512557 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO deguelin results in increased expression of EPS15 mRNA CTD PMID:33512557 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO deguelin results in decreased expression of ERN1 protein CTD PMID:25322282 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO deguelin results in increased expression of ERO1A mRNA CTD PMID:33512557 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression ISO deguelin results in increased expression of ETF1 mRNA CTD PMID:33512557 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810
JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO deguelin results in decreased expression of ETNK1 mRNA CTD PMID:33512557 NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO deguelin results in increased expression of ETS1 mRNA CTD PMID:33512557 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Etv1 ETS variant transcription factor 1 decreases expression ISO deguelin results in decreased expression of ETV1 mRNA CTD PMID:33512557 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
JBrowse link
G Evl Enah/Vasp-like decreases expression ISO deguelin results in decreased expression of EVL mRNA CTD PMID:33512557 NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344
JBrowse link
G Exosc4 exosome component 4 decreases expression ISO deguelin results in decreased expression of EXOSC4 mRNA CTD PMID:33512557 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
JBrowse link
G Exosc8 exosome component 8 increases expression ISO deguelin results in increased expression of EXOSC8 mRNA CTD PMID:33512557 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Fam174a family with sequence similarity 174, member A decreases expression ISO deguelin results in decreased expression of FAM174A mRNA CTD PMID:33512557 NCBI chr 9:95,742,815...95,761,083
Ensembl chr 9:95,742,927...95,761,081
JBrowse link
G Fam72a family with sequence similarity 72, member A increases expression ISO deguelin results in increased expression of FAM72A mRNA CTD PMID:33512557 NCBI chr13:42,968,409...42,978,976
Ensembl chr13:42,967,578...42,984,208
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO deguelin results in increased expression of FAS mRNA CTD PMID:33512557 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase decreases expression ISO deguelin results in decreased expression of FASN mRNA CTD PMID:33512557 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fastkd5 FAST kinase domains 5 decreases expression ISO deguelin results in decreased expression of FASTKD5 mRNA CTD PMID:33512557 NCBI chr 3:117,830,227...117,847,737
Ensembl chr 3:117,830,083...117,847,820
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO deguelin results in increased expression of FGF2 mRNA CTD PMID:33512557 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO deguelin results in increased expression of FIBIN mRNA CTD PMID:33512557 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase decreases expression ISO deguelin results in decreased expression of FIG4 mRNA CTD PMID:33512557 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 decreases expression ISO deguelin results in decreased expression of FKBP14 mRNA CTD PMID:33512557 NCBI chr 4:83,705,531...83,721,515
Ensembl chr 4:83,705,652...83,721,528
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO deguelin results in increased expression of FKBP4 mRNA CTD PMID:33512557 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Flna filamin A increases expression ISO deguelin results in increased expression of FLNA mRNA CTD PMID:33512557 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:9270009 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO deguelin results in increased expression of FOSL1 mRNA CTD PMID:33512557 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxj3 forkhead box J3 increases expression ISO deguelin results in increased expression of FOXJ3 mRNA CTD PMID:33512557 NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
JBrowse link
G Foxo4 forkhead box O4 decreases expression ISO deguelin results in decreased expression of FOXO4 mRNA CTD PMID:33512557 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Frzb frizzled-related protein increases expression ISO deguelin results in increased expression of FRZB mRNA CTD PMID:19861542 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO deguelin results in decreased expression of FSTL1 mRNA CTD PMID:33512557 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO deguelin results in increased expression of FTH1 mRNA CTD PMID:33512557 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO deguelin results in increased expression of FTL mRNA CTD PMID:33512557 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO deguelin results in decreased expression of FYN mRNA CTD PMID:33512557 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Fzd10 frizzled class receptor 10 increases expression ISO deguelin results in increased expression of FZD10 mRNA CTD PMID:19861542 NCBI chr12:28,098,371...28,101,566
Ensembl chr12:28,098,371...28,101,566
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO deguelin results in increased expression of FZD4 mRNA CTD PMID:19861542 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Fzd8 frizzled class receptor 8 increases expression ISO deguelin results in increased expression of FZD8 mRNA CTD PMID:19861542 NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 decreases expression ISO deguelin results in decreased expression of G3BP2 mRNA CTD PMID:33512557 NCBI chr14:15,932,356...16,020,555
Ensembl chr14:15,987,417...16,020,548
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO deguelin results in decreased expression of G6PD mRNA CTD PMID:33512557 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gaa alpha glucosidase decreases expression ISO deguelin results in decreased expression of GAA mRNA CTD PMID:33512557 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gabpb1 GA binding protein transcription factor subunit beta 1 increases expression ISO deguelin results in increased expression of GABPB1 mRNA CTD PMID:33512557 NCBI chr 3:113,879,972...113,924,744
Ensembl chr 3:113,879,973...113,923,696
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO deguelin results in increased expression of GADD45A mRNA CTD PMID:33512557 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression ISO deguelin results in decreased expression of GALE mRNA CTD PMID:33512557 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 decreases expression ISO deguelin results in decreased expression of GALNT3 mRNA CTD PMID:33512557 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO deguelin results in decreased expression of GAP43 mRNA CTD PMID:33512557 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gata2 GATA binding protein 2 increases expression ISO deguelin results in increased expression of GATA2 mRNA CTD PMID:33512557 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO deguelin results in increased expression of GCLC mRNA CTD PMID:33512557 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO deguelin results in increased expression of GCLM mRNA CTD PMID:33512557 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO deguelin results in increased expression of GDF15 mRNA CTD PMID:33512557 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO deguelin results in decreased expression of GINS2 mRNA CTD PMID:33512557 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO deguelin results in decreased expression of GINS3 mRNA CTD PMID:33512557 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO deguelin results in decreased expression of GLDC mRNA CTD PMID:33512557 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO deguelin results in decreased expression of GLI3 mRNA CTD PMID:33512557 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Glrx glutaredoxin decreases expression ISO deguelin results in decreased expression of GLRX mRNA CTD PMID:33512557 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gmip Gem-interacting protein decreases expression ISO deguelin results in decreased expression of GMIP mRNA CTD PMID:33512557 NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
JBrowse link
G Gmpr2 guanosine monophosphate reductase 2 decreases expression ISO deguelin results in decreased expression of GMPR2 mRNA CTD PMID:33512557 NCBI chr15:29,165,421...29,175,933
Ensembl chr15:29,165,783...29,174,935
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression ISO deguelin results in decreased expression of GNAI2 mRNA CTD PMID:33512557 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO deguelin results in decreased expression of GNPDA1 mRNA CTD PMID:33512557 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO deguelin results in increased expression of GOT1 mRNA CTD PMID:33512557 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpc1 glypican 1 decreases expression ISO deguelin results in decreased expression of GPC1 mRNA CTD PMID:33512557 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO deguelin results in increased expression of GRB10 mRNA CTD PMID:33512557 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Grb14 growth factor receptor bound protein 14 increases expression ISO deguelin results in increased expression of GRB14 mRNA CTD PMID:33512557 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression ISO deguelin results in decreased expression of GRIA2 mRNA CTD PMID:33512557 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression ISO deguelin results in decreased expression of GRIN2D mRNA CTD PMID:33512557 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grm4 glutamate metabotropic receptor 4 decreases expression ISO deguelin results in decreased expression of GRM4 mRNA CTD PMID:33512557 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grn granulin precursor decreases expression ISO deguelin results in decreased expression of GRN mRNA CTD PMID:33512557 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO deguelin results in decreased phosphorylation of GSK3B protein CTD PMID:19336726 PMID:21472727 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO deguelin results in increased expression of GSR mRNA CTD PMID:33512557 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO deguelin results in decreased expression of GSTM2 mRNA CTD PMID:33512557 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO deguelin results in increased expression of GTF2E2 mRNA CTD PMID:33512557 NCBI chr16:58,399,307...58,449,467
Ensembl chr16:58,399,107...58,449,371
JBrowse link
G Gtpbp8 GTP-binding protein 8 (putative) increases expression ISO deguelin results in increased expression of GTPBP8 mRNA CTD PMID:33512557 NCBI chr11:55,945,778...55,955,743
Ensembl chr11:55,945,795...55,955,635
JBrowse link
G Gucy2c guanylate cyclase 2C decreases expression ISO deguelin results in decreased expression of GUCY2C mRNA CTD PMID:33512557 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092
JBrowse link
G H1f0 H1.0 linker histone increases expression ISO deguelin results in increased expression of H1-0 mRNA CTD PMID:33512557 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO deguelin results in increased expression of H1-2 mRNA CTD PMID:33512557 NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H2az2 H2A.Z variant histone 2 decreases expression ISO deguelin results in decreased expression of H2AZ2 mRNA CTD PMID:33512557 NCBI chr14:81,293,299...81,312,209
Ensembl chr14:81,293,299...81,312,144
JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO deguelin results in increased expression of H2BC12 mRNA CTD PMID:33512557 NCBI chr17:42,485,746...42,486,126 JBrowse link
G Hba-a3 hemoglobin alpha, adult chain 3 increases expression ISO deguelin results in increased expression of HBA2 mRNA CTD PMID:33512557 NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO deguelin results in increased expression of HELLS mRNA CTD PMID:33512557 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO deguelin results in increased expression of HERPUD1 mRNA CTD PMID:33512557 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO deguelin results in increased expression of HES1 mRNA CTD PMID:33512557 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression ISO deguelin results in decreased expression of HEXA mRNA CTD PMID:33512557 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta increases expression ISO deguelin results in increased expression of HEXB mRNA CTD PMID:33512557 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hhip Hedgehog-interacting protein increases expression ISO deguelin results in increased expression of HHIP mRNA CTD PMID:33512557 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases degradation
multiple interactions
ISO deguelin results in increased degradation of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; deguelin metabolite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD PMID:17764071 PMID:18575727 PMID:19139008 PMID:22745725 PMID:27899277 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO deguelin results in increased expression of H2AC8 mRNA CTD PMID:33512557 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H increases expression ISO deguelin results in increased expression of H2AC11 mRNA CTD PMID:33512557 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO deguelin results in increased expression of H2BC5 mRNA CTD PMID:33512557 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO deguelin results in increased expression of HMGA2 mRNA CTD PMID:33512557 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO deguelin results in increased expression of HMMR mRNA CTD PMID:33512557 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO deguelin results in increased expression of HMOX1 mRNA CTD PMID:33512557 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M decreases expression ISO deguelin results in decreased expression of HNRNPM mRNA CTD PMID:33512557 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Homer2 homer scaffold protein 2 decreases expression ISO deguelin results in decreased expression of HOMER2 mRNA CTD PMID:33512557 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO deguelin results in increased expression of HPRT1 mRNA CTD PMID:33512557 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO deguelin results in increased expression of HSD17B11 mRNA CTD PMID:33512557 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 decreases expression ISO deguelin results in decreased expression of HSD17B8 mRNA CTD PMID:33512557 NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO deguelin results in increased expression of HSP90AA1 mRNA CTD PMID:33512557 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression ISO deguelin results in increased expression of HSP90AB1 mRNA CTD PMID:33512557 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO deguelin results in increased expression of HSPA1B mRNA CTD PMID:33512557 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO deguelin results in increased expression of HSPA4 mRNA CTD PMID:33512557 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO deguelin results in increased expression of HSPA8 mRNA CTD PMID:33512557 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO deguelin results in increased expression of HSPB1 mRNA CTD PMID:33512557 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO deguelin results in increased expression of HSPD1 mRNA CTD PMID:33512557 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO deguelin results in increased expression of HSPE1 mRNA CTD PMID:33512557 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO deguelin results in increased expression of HYOU1 mRNA CTD PMID:33512557 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:17015749 PMID:22745725 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO deguelin results in decreased expression of ID1 mRNA CTD PMID:33512557 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression ISO deguelin results in increased expression of IDH3A mRNA CTD PMID:33512557 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO deguelin results in decreased expression of IFI44 mRNA CTD PMID:33512557 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO deguelin results in increased expression of IFI44L mRNA CTD PMID:33512557 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO deguelin results in decreased expression of IFITM2 mRNA CTD PMID:33512557 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression ISO deguelin results in decreased expression of IFITM3 mRNA CTD PMID:33512557 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Ifng interferon gamma multiple interactions EXP
ISO
deguelin inhibits the reaction [Perfadex results in increased expression of IFNG protein]
[deguelin co-treated with OVAL protein] results in increased expression of IFNG protein
CTD PMID:22745725 PMID:28529457 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO deguelin results in increased expression of IFRD1 mRNA CTD PMID:33512557 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 increases expression ISO deguelin results in increased expression of IFRD2 mRNA CTD PMID:33512557 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of VEGFA mRNA] CTD PMID:17764071 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO deguelin metabolite results in decreased expression of IGF1R protein; deguelin results in decreased expression of IGF1R mRNA; deguelin results in decreased expression of IGF1R protein CTD PMID:19139008 PMID:33512557 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression ISO deguelin results in decreased expression of IGFBP2 mRNA CTD PMID:33512557 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 decreases expression ISO deguelin results in decreased expression of IGHMBP2 mRNA CTD PMID:33512557 NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO deguelin results in increased expression of IHH mRNA CTD PMID:19861542 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ikbip IKBKB interacting protein increases expression ISO deguelin results in increased expression of IKBIP mRNA CTD PMID:33512557 NCBI chr 7:25,579,759...25,598,548
Ensembl chr 7:25,579,832...25,605,162
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 decreases expression ISO deguelin results in decreased expression of IKZF1 mRNA CTD PMID:33512557 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il10 interleukin 10 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA] CTD PMID:22745725 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of IL13 protein] CTD PMID:28529457 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 multiple interactions EXP
ISO
deguelin inhibits the reaction [Oxygen deficiency results in decreased expression of IL4 mRNA]
deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 mRNA]; deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 protein]
CTD PMID:22745725 PMID:28529457 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of IL5 protein] CTD PMID:28529457 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions EXP deguelin inhibits the reaction [Perfadex results in decreased expression of IL6 protein] CTD PMID:22745725 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression ISO deguelin results in decreased expression of INA mRNA CTD PMID:33512557 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Ipo5 importin 5 increases expression ISO deguelin results in increased expression of IPO5 mRNA CTD PMID:33512557 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO deguelin results in increased expression of IQGAP1 mRNA CTD PMID:33512557 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein CTD PMID:25242579 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 decreases expression ISO deguelin results in decreased expression of ITPR2 mRNA CTD PMID:33512557 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO deguelin results in increased expression of JMJD6 mRNA CTD PMID:33512557 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO deguelin results in increased phosphorylation of JUN protein CTD PMID:25322282 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO deguelin results in decreased expression of JUNB mRNA CTD PMID:33512557 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kat6a lysine acetyltransferase 6A increases expression ISO deguelin results in increased expression of KAT6A mRNA CTD PMID:33512557 NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 increases expression ISO deguelin results in increased expression of KCNJ8 mRNA CTD PMID:33512557 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO deguelin results in decreased expression of KCNK1 mRNA CTD PMID:33512557 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression ISO deguelin results in increased expression of KCTD9 mRNA CTD PMID:33512557 NCBI chr15:41,942,165...41,969,862
Ensembl chr15:41,942,381...41,969,862
JBrowse link
G Kdm5b lysine demethylase 5B decreases expression ISO deguelin results in decreased expression of KDM5B mRNA CTD PMID:33512557 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO deguelin metabolite results in decreased expression of KDR protein; deguelin results in decreased expression of KDR protein CTD PMID:19139008 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO deguelin results in increased expression of KEAP1 mRNA CTD PMID:33512557 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO deguelin results in increased expression of KHDRBS3 mRNA CTD PMID:33512557 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Kif15 kinesin family member 15 increases expression ISO deguelin results in increased expression of KIF15 mRNA CTD PMID:33512557 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO deguelin results in increased expression of KIF20A mRNA CTD PMID:33512557 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif23 kinesin family member 23 increases expression ISO deguelin results in increased expression of KIF23 mRNA CTD PMID:33512557 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C increases expression ISO deguelin results in increased expression of KIF2C mRNA CTD PMID:33512557 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO deguelin results in decreased expression of KIF5C mRNA CTD PMID:33512557 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO deguelin results in decreased expression of KIT mRNA CTD PMID:33512557 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO deguelin results in increased expression of KLHL24 mRNA CTD PMID:34642769 NCBI chr11:80,843,621...80,877,693
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Knl1 kinetochore scaffold 1 increases expression ISO deguelin results in increased expression of KNL1 mRNA CTD PMID:33512557 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Krt17 keratin 17 increases expression ISO deguelin results in increased expression of KRT17 mRNA CTD PMID:33512557 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt18 keratin 18 increases expression
multiple interactions
ISO deguelin results in increased expression of KRT18 protein
deguelin inhibits the reaction [TGFB1 protein results in decreased expression of KRT18 protein]
CTD PMID:22986522 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Ktn1 kinectin 1 increases expression ISO deguelin results in increased expression of KTN1 mRNA CTD PMID:33512557 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
JBrowse link
G L1cam L1 cell adhesion molecule decreases expression ISO deguelin results in decreased expression of L1CAM mRNA CTD PMID:33512557 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lamc2 laminin subunit gamma 2 decreases expression ISO deguelin results in decreased expression of LAMC2 mRNA CTD PMID:33512557 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 decreases expression ISO deguelin results in decreased expression of LAMP1 mRNA CTD PMID:33512557 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression ISO deguelin results in increased expression of LEF1 mRNA CTD PMID:33512557 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgmn legumain decreases expression ISO deguelin results in decreased expression of LGMN mRNA CTD PMID:33512557 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
JBrowse link
G Lmod1 leiomodin 1 decreases expression ISO deguelin results in decreased expression of LMOD1 mRNA CTD PMID:33512557 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G LOC100125598 metallothionein 1a pseudogene increases expression ISO deguelin results in increased expression of MT1G mRNA CTD PMID:33512557 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G LOC102549061 histone H2B type 1-N-like increases expression ISO deguelin results in increased expression of H2BC3 mRNA CTD PMID:33512557 NCBI chr17:41,380,058...41,380,685 JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like decreases expression ISO deguelin results in decreased expression of CBR1 mRNA CTD PMID:33512557 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO deguelin results in increased expression of H2AC6 mRNA CTD PMID:33512557 NCBI chr17:42,707,863...42,708,420 JBrowse link
G LOC498265 similar to hypothetical protein FLJ10706 decreases expression ISO deguelin results in decreased expression of C1ORF112 mRNA CTD PMID:33512557 NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804
JBrowse link
G LOC684841 similar to CG31613-PA increases expression ISO deguelin results in increased expression of H3C10 mRNA CTD PMID:33512557
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO deguelin results in increased expression of HSPA6 mRNA CTD PMID:33512557 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lox lysyl oxidase multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:22745725 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO deguelin results in decreased expression of LOXL1 mRNA CTD PMID:33512557 NCBI chr 8:58,692,592...58,716,356
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lpar2 lysophosphatidic acid receptor 2 decreases expression ISO deguelin results in decreased expression of LPAR2 mRNA CTD PMID:33512557 NCBI chr16:19,592,067...19,600,850
Ensembl chr16:19,595,655...19,599,998
JBrowse link
G Lrp4 LDL receptor related protein 4 increases expression ISO deguelin results in increased expression of LRP4 mRNA CTD PMID:33512557 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO deguelin results in increased expression of LSM2 mRNA CTD PMID:33512557 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266
JBrowse link
G Lss lanosterol synthase decreases expression ISO deguelin results in decreased expression of LSS mRNA CTD PMID:33512557 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 decreases expression ISO deguelin results in decreased expression of MAGI1 mRNA CTD PMID:33512557 NCBI chr 4:126,205,667...126,811,354
Ensembl chr 4:126,206,816...126,811,691
JBrowse link
G Map1b microtubule-associated protein 1B decreases expression ISO deguelin results in decreased expression of MAP1B mRNA CTD PMID:33512557 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO deguelin results in increased expression of MAP1LC3B mRNA CTD PMID:33512557 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO deguelin results in decreased expression of MAP2 mRNA CTD PMID:33512557 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression ISO deguelin metabolite results in decreased expression of MAP2K1 protein; deguelin results in decreased expression of MAP2K1 protein CTD PMID:19139008 PMID:19336726 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO deguelin results in decreased expression of MAP2K2 protein CTD PMID:19336726 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 decreases expression ISO deguelin results in decreased expression of MAP2K7 protein CTD PMID:25322282 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO deguelin affects the expression of MAP3K3 protein CTD PMID:25322282 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map6 microtubule-associated protein 6 decreases expression ISO deguelin results in decreased expression of MAP6 mRNA CTD PMID:33512557 NCBI chr 1:153,568,019...153,634,415
Ensembl chr 1:153,568,368...153,634,414
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO deguelin affects the phosphorylation of MAPK1 protein CTD PMID:25322282 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 decreases expression ISO deguelin results in decreased expression of MAPK12 mRNA CTD PMID:33512557 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like increases expression ISO deguelin results in increased expression of MAPK1IP1L mRNA CTD PMID:33512557 NCBI chr15:20,545,028...20,567,010
Ensembl chr15:20,545,059...20,569,674
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation
decreases expression
ISO deguelin affects the phosphorylation of MAPK3 protein
deguelin results in decreased expression of MAPK3 mRNA
CTD PMID:25322282 PMID:33512557 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 decreases expression ISO deguelin results in decreased expression of MAPRE3 mRNA CTD PMID:33512557 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO deguelin results in decreased expression of MARCKS mRNA CTD PMID:33512557 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO deguelin results in decreased expression of MAT2A mRNA CTD PMID:33512557 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 decreases expression ISO deguelin results in decreased expression of MBTPS1 mRNA CTD PMID:33512557 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO deguelin results in decreased expression of MCL1 protein CTD PMID:21472727 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO deguelin results in decreased expression of MCM3 mRNA CTD PMID:33512557 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 decreases expression ISO deguelin results in decreased expression of MCOLN1 mRNA CTD PMID:33512557 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 increases expression ISO deguelin results in increased expression of MCUR1 mRNA CTD PMID:33512557 NCBI chr17:21,142,526...21,159,651
Ensembl chr17:21,141,602...21,159,651
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO deguelin results in increased expression of MDM2 mRNA CTD PMID:33512557 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me1 malic enzyme 1 increases expression ISO deguelin results in increased expression of ME1 mRNA CTD PMID:33512557 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Me2 malic enzyme 2 increases expression ISO deguelin results in increased expression of ME2 mRNA CTD PMID:33512557 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987
JBrowse link
G Metrn meteorin, glial cell differentiation regulator decreases expression ISO deguelin results in decreased expression of METRN mRNA CTD PMID:33512557 NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
JBrowse link
G Mfsd10 major facilitator superfamily domain containing 10 decreases expression ISO deguelin results in decreased expression of MFSD10 mRNA CTD PMID:33512557 NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377
JBrowse link
G Mfsd14a major facilitator superfamily domain containing 14A increases expression ISO deguelin results in increased expression of MFSD14A mRNA CTD PMID:33512557 NCBI chr 2:204,579,174...204,611,600
Ensembl chr 2:204,579,174...204,659,319
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO deguelin results in decreased expression of MGMT mRNA CTD PMID:22227970 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO deguelin results in decreased expression of MKI67 protein CTD PMID:22623043 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases expression ISO deguelin results in decreased expression of MLLT11 mRNA CTD PMID:33512557 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO deguelin results in decreased expression of MMP1 protein CTD PMID:25322282 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression ISO deguelin results in decreased expression of MMP13 protein CTD PMID:25322282 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO deguelin results in decreased expression of and results in decreased activity of MMP2 protein
deguelin results in decreased expression of MMP2 mRNA; deguelin results in decreased expression of MMP2 protein
CTD PMID:25322282 PMID:26884827 PMID:33512557 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO deguelin results in decreased expression of MMP7 mRNA CTD PMID:25322282 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases activity
ISO deguelin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
deguelin results in decreased expression of MMP9 mRNA; deguelin results in decreased expression of MMP9 protein
deguelin results in decreased activity of MMP9 protein
CTD PMID:17015749 PMID:25322282 PMID:26884827 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnd1 meiotic nuclear divisions 1 increases expression ISO deguelin results in increased expression of MND1 mRNA CTD PMID:33512557 NCBI chr 2:169,433,538...169,496,081
Ensembl chr 2:169,433,540...169,496,096
JBrowse link
G Morn2 MORN repeat containing 2 decreases expression ISO deguelin results in decreased expression of MORN2 mRNA CTD PMID:33512557 NCBI chr 6:14,718,799...14,725,281 JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP deguelin promotes the reaction [Oxygen deficiency results in increased expression of MRC1 mRNA] CTD PMID:22745725 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 increases expression ISO deguelin results in increased expression of MRPL19 mRNA CTD PMID:33512557 NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053
JBrowse link
G Mrpl58 mitochondrial ribosomal protein L58 increases expression ISO deguelin results in increased expression of MRPL58 mRNA CTD PMID:33512557 NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 decreases expression ISO deguelin results in decreased expression of MRPS6 mRNA CTD PMID:33512557 NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
JBrowse link
G Msh6 mutS homolog 6 increases expression ISO deguelin results in increased expression of MSH6 mRNA CTD PMID:33512557 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msi2 musashi RNA-binding protein 2 decreases expression ISO deguelin results in decreased expression of MSI2 mRNA CTD PMID:33512557 NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO deguelin results in decreased expression of ND6 mRNA CTD PMID:33512557 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt2A metallothionein 2A increases expression ISO deguelin results in increased expression of MT2A mRNA CTD PMID:33512557 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtf2 metal response element binding transcription factor 2 increases expression ISO deguelin results in increased expression of MTF2 mRNA CTD PMID:33512557 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 increases expression ISO deguelin results in increased expression of MTHFD1 mRNA CTD PMID:33512557 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO deguelin results in increased expression of MTHFD2 mRNA CTD PMID:33512557 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of MTOR protein; deguelin results in decreased expression of MTOR protein
deguelin results in decreased phosphorylation of MTOR protein
CTD PMID:19139008 PMID:27255535 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO deguelin results in decreased expression of MUC1 mRNA CTD PMID:33512557 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of MUC5AC mRNA] CTD PMID:28529457 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Mybl1 MYB proto-oncogene like 1 decreases expression ISO deguelin results in decreased expression of MYBL1 mRNA CTD PMID:33512557 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
decreases expression
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MYC protein]
deguelin results in increased expression of MYC mRNA
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]
CTD PMID:9270009 PMID:17015749 PMID:21472727 PMID:33512557 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl1 myosin, light chain 1 decreases expression ISO deguelin results in decreased expression of MYL1 mRNA CTD PMID:33512557 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO deguelin results in decreased expression of MYL4 mRNA CTD PMID:33512557 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO deguelin results in increased expression of NAMPT mRNA CTD PMID:33512557 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO deguelin results in decreased expression of NAT1 mRNA CTD PMID:33512557 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nav1 neuron navigator 1 decreases expression ISO deguelin results in decreased expression of NAV1 mRNA CTD PMID:33512557 NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
JBrowse link
G Ncan neurocan decreases expression ISO deguelin results in decreased expression of NCAN mRNA CTD PMID:33512557 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO deguelin results in increased expression of NCAPH mRNA CTD PMID:33512557 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Nck1 NCK adaptor protein 1 increases expression ISO deguelin results in increased expression of NCK1 mRNA CTD PMID:33512557 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 decreases expression ISO deguelin results in decreased expression of NCOA3 mRNA; deguelin results in decreased expression of NCOA3 protein CTD PMID:19365708 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO deguelin results in decreased expression of NDRG1 mRNA CTD PMID:33512557 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression ISO deguelin results in increased expression of NDUFV3 mRNA CTD PMID:33512557 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO deguelin results in decreased expression of NEFH mRNA CTD PMID:33512557 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression ISO deguelin results in decreased expression of NEFL mRNA CTD PMID:33512557 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Neil3 nei-like DNA glycosylase 3 increases expression ISO deguelin results in increased expression of NEIL3 mRNA CTD PMID:33512557 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression
increases expression
ISO deguelin results in decreased expression of NEK2 mRNA; deguelin results in decreased expression of NEK2 protein
deguelin results in increased expression of NEK2 mRNA
CTD PMID:28509438 PMID:33512557 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Neurod1 neuronal differentiation 1 increases expression ISO deguelin results in increased expression of NEUROD1 mRNA CTD PMID:33512557 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO deguelin results in increased expression of NFE2L1 mRNA CTD PMID:33512557 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
deguelin inhibits the reaction [OVAL protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:17015749 PMID:22623043 PMID:28529457 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nisch nischarin decreases expression ISO deguelin results in decreased expression of NISCH mRNA CTD PMID:33512557 NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression ISO deguelin results in decreased expression of NOLC1 mRNA CTD PMID:33512557 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression ISO deguelin results in increased expression of NOP58 mRNA CTD PMID:33512557 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
ISO deguelin results in decreased expression of NOS2 protein
deguelin inhibits the reaction [OVAL protein results in increased expression of NOS2 mRNA]
CTD PMID:25322282 PMID:28529457 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression
increases expression
ISO deguelin results in decreased expression of NOS3 protein
deguelin results in increased expression of NOS3 mRNA
CTD PMID:19336726 PMID:34642769 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch2 notch receptor 2 increases expression ISO deguelin results in increased expression of NOTCH2 mRNA CTD PMID:33512557 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Notch3 notch receptor 3 decreases expression ISO deguelin results in decreased expression of NOTCH3 mRNA CTD PMID:33512557 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 decreases expression ISO deguelin results in decreased expression of NPDC1 mRNA CTD PMID:33512557 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Npm1 nucleophosmin 1 decreases expression
multiple interactions
increases response to substance
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of TP53 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein
CTD PMID:25242579 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nptx1 neuronal pentraxin 1 decreases expression ISO deguelin results in decreased expression of NPTX1 mRNA CTD PMID:33512557 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO deguelin results in increased expression of NQO1 mRNA CTD PMID:33512557 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO deguelin results in decreased expression of NR2F1 mRNA CTD PMID:33512557 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO deguelin results in increased expression of NR3C1 mRNA CTD PMID:33512557 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO deguelin results in decreased expression of NR4A2 mRNA CTD PMID:33512557 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO deguelin results in decreased expression of NR5A1 mRNA CTD PMID:33512557 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO deguelin results in decreased expression of NRAS mRNA CTD PMID:33512557 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO deguelin results in decreased expression of NRCAM mRNA CTD PMID:33512557 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO deguelin results in increased expression of NRIP1 mRNA CTD PMID:33512557 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nrxn1 neurexin 1 decreases expression ISO deguelin results in decreased expression of NRXN1 mRNA CTD PMID:33512557 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 decreases expression ISO deguelin results in decreased expression of NSG1 mRNA CTD PMID:33512557 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of NT5E protein] CTD PMID:27899277 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression ISO deguelin results in decreased expression of NTRK1 mRNA CTD PMID:33512557 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Nudcd3 NudC domain containing 3 decreases expression ISO deguelin results in decreased expression of NUDCD3 mRNA CTD PMID:33512557 NCBI chr14:80,975,417...81,059,183
Ensembl chr14:80,976,328...81,058,962
JBrowse link
G Nudt5 nudix hydrolase 5 decreases expression ISO deguelin results in decreased expression of NUDT5 mRNA CTD PMID:33512557 NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001
JBrowse link
G Nudt9 nudix hydrolase 9 increases expression ISO deguelin results in increased expression of NUDT9 mRNA CTD PMID:33512557 NCBI chr14:5,675,376...5,693,332
Ensembl chr14:5,675,382...5,693,142
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases expression ISO deguelin results in increased expression of NUF2 mRNA CTD PMID:33512557 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nup85 nucleoporin 85 decreases expression ISO deguelin results in decreased expression of NUP85 mRNA CTD PMID:33512557 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043
JBrowse link
G Nup88 nucleoporin 88 decreases expression ISO deguelin results in decreased expression of NUP88 mRNA CTD PMID:33512557 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G Nup98 nucleoporin 98 and 96 precursor decreases expression ISO deguelin results in decreased expression of NUP98 mRNA; deguelin results in decreased expression of NUP98 protein CTD PMID:17490514 NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415
JBrowse link
G Nvl nuclear VCP-like increases expression ISO deguelin results in increased expression of NVL mRNA CTD PMID:33512557 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 increases expression ISO deguelin results in increased expression of OAZ1 mRNA CTD PMID:33512557 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity
multiple interactions
ISO deguelin results in increased activity of ODC1 protein
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
CTD PMID:9270009 PMID:9834970 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Oip5 Opa interacting protein 5 increases expression ISO deguelin results in increased expression of OIP5 mRNA CTD PMID:33512557 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
JBrowse link
G Olfml2b olfactomedin-like 2B decreases expression ISO deguelin results in decreased expression of OLFML2B mRNA CTD PMID:33512557 NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
JBrowse link
G Onecut1 one cut homeobox 1 decreases expression ISO deguelin results in decreased expression of ONECUT1 mRNA CTD PMID:33512557 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Orc3 origin recognition complex, subunit 3 decreases expression ISO deguelin results in decreased expression of ORC3 mRNA CTD PMID:33512557 NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633
JBrowse link
G Oxa1l OXA1L, mitochondrial inner membrane protein increases expression ISO deguelin results in increased expression of OXA1L mRNA CTD PMID:33512557 NCBI chr15:27,813,688...27,821,319
Ensembl chr15:27,813,625...27,821,319
JBrowse link
G P2rx3 purinergic receptor P2X 3 decreases expression ISO deguelin results in decreased expression of P2RX3 mRNA CTD PMID:33512557 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression ISO deguelin results in increased expression of PAFAH1B1 mRNA CTD PMID:33512557 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Pafah1b3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 decreases expression ISO deguelin results in decreased expression of PAFAH1B3 mRNA CTD PMID:33512557 NCBI chr 1:80,881,263...80,883,789
Ensembl chr 1:80,881,309...80,883,893
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO deguelin results in decreased expression of PAIP1 mRNA CTD PMID:33512557 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]
deguelin results in increased cleavage of PARP1 protein
deguelin metabolite results in increased expression of PARP1 protein modified form; deguelin results in increased expression of PARP1 protein modified form
CTD PMID:17015749 PMID:17035597 PMID:19139008 PMID:22986522 PMID:25242579 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 increases expression ISO deguelin results in increased expression of PARP2 mRNA CTD PMID:33512557 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Pbk PDZ binding kinase increases expression ISO deguelin results in increased expression of PBK mRNA CTD PMID:33512557 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pcdha1 protocadherin alpha 1 decreases expression ISO deguelin results in decreased expression of PCDHA1 mRNA CTD PMID:33512557 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha9 protocadherin alpha 9 decreases expression ISO deguelin results in decreased expression of PCDHA9 mRNA CTD PMID:33512557
G Pde1a phosphodiesterase 1A decreases expression ISO deguelin results in decreased expression of PDE1A mRNA CTD PMID:33512557 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pdgfb platelet derived growth factor subunit B decreases expression ISO deguelin results in decreased expression of PDGFB mRNA CTD PMID:33512557 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X increases expression ISO deguelin results in increased expression of PDHX mRNA CTD PMID:33512557 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO deguelin metabolite results in decreased expression of PDK1 protein; deguelin results in decreased expression of PDK1 protein CTD PMID:19139008 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO deguelin results in decreased expression of PEBP1 mRNA CTD PMID:33512557 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Peg10 paternally expressed 10 decreases expression ISO deguelin results in decreased expression of PEG10 mRNA CTD PMID:33512557 NCBI chr 4:32,842,394...32,855,641
Ensembl chr 4:32,848,493...32,852,621
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 decreases expression ISO deguelin results in decreased expression of PFKFB4 mRNA CTD PMID:33512557 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Pfkl phosphofructokinase, liver type decreases expression ISO deguelin results in decreased expression of PFKL mRNA CTD PMID:33512557 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
JBrowse link
G Pfkp phosphofructokinase, platelet increases expression ISO deguelin results in increased expression of PFKP mRNA CTD PMID:34642769 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pga5 pepsinogen A5 increases expression ISO deguelin results in increased expression of PGA5 mRNA CTD PMID:33512557 NCBI chr 1:207,317,021...207,327,156
Ensembl chr 1:207,317,021...207,327,156
JBrowse link
G Pgf placental growth factor decreases expression ISO deguelin results in decreased expression of PGF mRNA CTD PMID:33512557 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO deguelin results in decreased expression of PGK1 mRNA CTD PMID:33512557 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO deguelin results in increased expression of PGM1 mRNA CTD PMID:33512557 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO deguelin results in increased expression of PHGDH mRNA CTD PMID:33512557 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda1