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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dobutamine
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Accession:CHEBI:4670 term browser browse the term
Definition:A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.
Synonyms:exact_synonym: 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
 related_synonym: (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol;   3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine;   4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol;   DL-dobutamine;   Formula=C18H23NO3;   InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3;   InChIKey=JRWZLRBJNMZMFE-UHFFFAOYSA-N;   SMILES=CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1;   dobutamina;   dobutaminum;   rac-dobutamine;   racemic-dobutamine
 alt_id: CHEBI:184505;   CHEBI:554519
 xref: Beilstein:2946389;   CAS:34368-04-2;   DrugBank:DB00841;   Drug_Central:937;   HMDB:HMDB0014979;   KEGG:C06967;   KEGG:D03879;   LINCS:LSM-1807
 xref_mesh: MESH:D004280
 xref: PMID:11280019;   PMID:11950781;   PMID:18323735;   PMID:22537238;   Patent:DE2317710;   Patent:US3987200;   Reaxys:2946389;   Wikipedia:Dobutamine

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Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        molecular messenger 0
          monoamine molecular messenger 0
            catecholamine 0
              dobutamine 0
                (R)-dobutamine 0
                (S)-dobutamine 0
                dobutamine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    main group molecular entity 0
                      s-block molecular entity 0
                        hydrogen molecular entity 0
                          hydrides 0
                            inorganic hydride 0
                              pnictogen hydride 0
                                nitrogen hydride 0
                                  azane 0
                                    ammonia 0
                                      organic amino compound 0
                                        aralkylamino compound 0
                                          monoamine 0
                                            monoamine molecular messenger 0
                                              catecholamine 0
                                                dobutamine 0
                                                  (R)-dobutamine 0
                                                  (S)-dobutamine 0
                                                  dobutamine hydrochloride 0
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