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G |
Il13 |
interleukin 13 |
decreases expression decreases secretion |
ISO |
Etazolate results in decreased expression of IL13 mRNA Etazolate results in decreased secretion of IL13 protein |
CTD |
PMID:16083514 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Ltc4s |
leukotriene C4 synthase |
decreases secretion |
ISO |
Etazolate results in decreased secretion of LTC4S protein |
CTD |
PMID:16083514 |
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NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
EXP |
ibudilast inhibits the reaction [Dronabinol results in increased expression of AIF1 protein] |
CTD |
PMID:26499171 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
ibudilast inhibits the reaction [Dronabinol results in increased expression of CNR2 protein] |
CTD |
PMID:26499171 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Ifng |
interferon gamma |
decreases expression |
ISO |
ibudilast results in decreased expression of IFNG protein |
CTD |
PMID:14664469 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il12a |
interleukin 12A |
decreases expression multiple interactions |
ISO |
ibudilast results in decreased expression of IL12A mRNA ibudilast results in decreased expression of [IL12A protein binds to IL12B protein] |
CTD |
PMID:14664469 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
decreases expression multiple interactions |
ISO |
ibudilast results in decreased expression of IL12B mRNA ibudilast results in decreased expression of [IL12A protein binds to IL12B protein] |
CTD |
PMID:14664469 |
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NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
ibudilast inhibits the reaction [Dronabinol results in increased expression of NOS2 protein] |
CTD |
PMID:26499171 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
ibudilast inhibits the reaction [Dronabinol results in increased expression of PTGS2 protein] |
CTD |
PMID:26499171 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
ibudilast inhibits the reaction [Dronabinol results in increased expression of TNF protein] |
CTD |
PMID:26499171 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions increases expression |
EXP |
Thyroxine inhibits the reaction [pexacerfont results in increased expression of TSHB protein] |
CTD |
PMID:33340518 |
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NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases metabolic processing |
ISO |
CYP1A1 protein results in increased metabolism of riociguat |
CTD |
PMID:30950278 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Kcnk3 |
potassium two pore domain channel subfamily K member 3 |
decreases response to substance increases activity |
ISO |
KCNK3 protein mutant form results in decreased susceptibility to riociguat riociguat results in increased activity of KCNK3 protein |
CTD |
PMID:30365877 |
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NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
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