CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | zoledronic acid |
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Accession: | CHEBI:46557
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browse the term
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Definition: | An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position. |
Synonyms: | exact_synonym: | [1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) |
| related_synonym: | (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid; (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid; Formula=C5H10N2O7P2; InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14); InChIKey=XRASPMIURGNCCH-UHFFFAOYSA-N; Reclast; SMILES=OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O; ZOL |
| xref: | Beilstein:9205049; CAS:118072-93-8; Chemspider:61986; DrugBank:DB00399; Drug_Central:2868; Gmelin:2609374; KEGG:D08689 |
| xref_mesh: | MESH:C088658 |
| xref: | PDBeChem:ZOL; PMCID:PMC8090009; PMID:12183663; PMID:15161327; PMID:15324309; PMID:16414486; PMID:17691952; PMID:18982915; PMID:19751105; PMID:33908127; PMID:33984339; PMID:34081204; PMID:34157824; PMID:34324430; PMID:34341833; PMID:34393156; PMID:34413050; PMID:34435997; PMID:34447747; PMID:34475752; PMID:34560734; PMID:34585443; Patent:US4939130; Wikipedia:Zoledronic_Acid |
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A4galt |
alpha 1,4-galactosyltransferase |
increases expression |
ISO |
zoledronic acid results in increased expression of A4GALT mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071
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Aadat |
aminoadipate aminotransferase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AADAT mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
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Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of AARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Abca12 |
ATP binding cassette subfamily A member 12 |
increases expression |
ISO |
zoledronic acid results in increased expression of ABCA12 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
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Abca4 |
ATP binding cassette subfamily A member 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of ABCA4 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
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NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
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Abcb6 |
ATP binding cassette subfamily B member 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ABCB6 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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Abcc5 |
ATP binding cassette subfamily C member 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ABCC5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ABCG2 mRNA |
CTD |
PMID:18225567 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Abhd17c |
abhydrolase domain containing 17C, depalmitoylase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ABHD17C mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:138,084,632...138,125,595
Ensembl chr 1:138,084,634...138,125,595
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Abi3bp |
ABI family member 3 binding protein |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ABI3BP mRNA |
CTD |
PMID:24714768 |
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NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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Abtb3 |
ankyrin repeat and BTB domain containing 3 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of ABTB3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:18,035,151...18,310,718
Ensembl chr 7:18,036,083...18,310,834
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Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACAA1 mRNA |
CTD |
PMID:28871336 |
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NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
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Acadl |
acyl-CoA dehydrogenase, long chain |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACADL mRNA |
CTD |
PMID:28871336 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acadm |
acyl-CoA dehydrogenase medium chain |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACADM mRNA |
CTD |
PMID:28871336 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acat2 |
acetyl-CoA acetyltransferase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ACAT2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acbd4 |
acyl-CoA binding domain containing 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACBD4 mRNA |
CTD |
PMID:20977926 |
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NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500
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Acmsd |
aminocarboxymuconate semialdehyde decarboxylase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACMSD mRNA |
CTD |
PMID:24714768 |
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NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209
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Acox1 |
acyl-CoA oxidase 1 |
decreases expression multiple interactions |
ISO |
zoledronic acid results in decreased expression of ACOX1 mRNA; zoledronic acid results in decreased expression of ACOX1 protein Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acox2 |
acyl-CoA oxidase 2 |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acp3 |
acid phosphatase 3 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of ACP3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of ACSL1 mRNA; Zoledronic Acid results in decreased expression of ACSL1 protein |
CTD |
PMID:25596134 PMID:28871336 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACSL3 protein |
CTD |
PMID:28871336 |
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NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of ACSL5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACSM3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ACSS2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
ISO |
zoledronic acid results in increased expression of ACTA2 protein Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] |
CTD |
PMID:28871336 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actbl2 |
actin, beta-like 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ACTBL2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767
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Actg2 |
actin gamma 2, smooth muscle |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACTG2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Actn1 |
actinin, alpha 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACTN1 protein |
CTD |
PMID:28871336 |
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NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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Actn4 |
actinin alpha 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ACTN4 protein |
CTD |
PMID:28871336 |
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NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions decreases activity increases expression |
ISO |
ADAM17 protein promotes the reaction [zoledronic acid results in decreased expression of TNFSF11 protein] zoledronic acid results in decreased activity of ADAM17 protein zoledronic acid results in increased expression of ADAM17 protein |
CTD |
PMID:14753746 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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Adam19 |
ADAM metallopeptidase domain 19 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADAM19 mRNA |
CTD |
PMID:24714768 |
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NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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Adam28 |
ADAM metallopeptidase domain 28 |
increases expression |
ISO |
zoledronic acid results in increased expression of ADAM28 mRNA |
CTD |
PMID:24714768 |
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NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
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Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
increases expression |
ISO |
zoledronic acid results in increased expression of ADAMTS9 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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Adamtsl3 |
ADAMTS-like 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADAMTSL3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
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Adgrf1 |
adhesion G protein-coupled receptor F1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ADGRF1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704
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Adgrg1 |
adhesion G protein-coupled receptor G1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADGRG1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
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Adgrl1 |
adhesion G protein-coupled receptor L1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADGRL1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
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Adgrv1 |
adhesion G protein-coupled receptor V1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ADGRV1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
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Adh6 |
alcohol dehydrogenase 6 (class V) |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of ADH6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
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Adm2 |
adrenomedullin 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADM2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
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Adsl |
adenylosuccinate lyase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ADSL mRNA |
CTD |
PMID:20977926 |
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NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
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Afp |
alpha-fetoprotein |
increases expression |
ISO |
zoledronic acid results in increased expression of AFP protein |
CTD |
PMID:28871336 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of AGPAT5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:70,939,480...70,985,745
Ensembl chr16:70,943,135...70,985,560
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Agr2 |
anterior gradient 2, protein disulphide isomerase family member |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AGR2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
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Agrn |
agrin |
increases expression |
ISO |
zoledronic acid results in increased expression of AGRN protein |
CTD |
PMID:28871336 |
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NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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Ahnak2 |
AHNAK nucleoprotein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AHNAK2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463
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Ahr |
aryl hydrocarbon receptor |
affects activity |
ISO |
zoledronic acid affects the activity of AHR protein |
CTD |
PMID:25596134 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ahsg |
alpha-2-HS-glycoprotein |
increases expression |
ISO |
zoledronic acid results in increased expression of AHSG protein |
CTD |
PMID:28871336 |
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NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
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Ak3 |
adenylate kinase 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AK3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
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Ak5 |
adenylate kinase 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AK5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
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Akap7 |
A-kinase anchoring protein 7 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AKAP7 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
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Akip1 |
A-kinase interacting protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of AKIP1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648
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Akirin2 |
akirin 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AKIRIN2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
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Akr1a1 |
aldo-keto reductase family 1 member A1 |
increases expression |
ISO |
zoledronic acid results in increased expression of AKR1A1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases expression |
ISO |
zoledronic acid results in increased expression of AKR1B1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr1c2 |
aldo-keto reductase family 1, member C2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AKR1C2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein |
CTD |
PMID:19530242 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Akt1s1 |
AKT1 substrate 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of AKT1S1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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Alb |
albumin |
increases expression |
ISO |
zoledronic acid results in increased expression of ALB protein |
CTD |
PMID:28871336 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh18a1 |
aldehyde dehydrogenase 18 family, member A1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ALDH18A1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
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Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
increases expression |
ISO |
zoledronic acid results in increased expression of ALDH1A3 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Aldh3a2 |
aldehyde dehydrogenase 3 family, member A2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ALDH3A2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
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Aldh8a1 |
aldehyde dehydrogenase 8 family, member A1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ALDH8A1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
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Alox5 |
arachidonate 5-lipoxygenase |
increases expression |
ISO |
zoledronic acid results in increased expression of ALOX5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
increases expression |
ISO |
zoledronic acid results in increased expression of ALOX5AP mRNA |
CTD |
PMID:20977926 PMID:24714768 |
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NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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G |
Alpk2 |
alpha-kinase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ALPK2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
decreases activity multiple interactions |
ISO |
zoledronic acid results in decreased activity of ALPL protein TNFRSF11B protein affects the reaction [zoledronic acid results in decreased activity of ALPL protein] |
CTD |
PMID:18496637 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Als2cl |
ALS2 C-terminal like |
increases expression |
ISO |
zoledronic acid results in increased expression of ALS2CL mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
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G |
Ank2 |
ankyrin 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ANK2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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G |
Ankef1 |
ankyrin repeat and EF-hand domain containing 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ANKEF1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 3:123,847,832...123,883,060
Ensembl chr 3:123,847,817...123,883,059
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G |
Ankra2 |
ankyrin repeat family A member 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ANKRA2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730
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G |
Ankrd10 |
ankyrin repeat domain 10 |
increases expression |
ISO |
zoledronic acid results in increased expression of ANKRD10 mRNA |
CTD |
PMID:20977926 |
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NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
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G |
Ankrd22 |
ankyrin repeat domain 22 |
increases expression |
ISO |
zoledronic acid results in increased expression of ANKRD22 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381
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G |
Anln |
anillin, actin binding protein |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ANLN mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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G |
Anpep |
alanyl aminopeptidase, membrane |
increases expression |
ISO |
zoledronic acid results in increased expression of ANPEP mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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G |
Anxa2 |
annexin A2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ANXA2 protein |
CTD |
PMID:28871336 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Ap1s2 |
adaptor related protein complex 1 subunit sigma 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of AP1S2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr X:30,572,746...30,598,961
Ensembl chr X:30,572,751...30,597,262
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G |
Ap1s3 |
adaptor related protein complex 1 subunit sigma 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of AP1S3 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
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G |
Ap4b1 |
adaptor related protein complex 4 subunit beta 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of AP4B1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:191,318,485...191,330,531
Ensembl chr 2:191,318,482...191,330,531
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of APAF1 mRNA |
CTD |
PMID:28871336 |
|
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apba3 |
amyloid beta precursor protein binding family A member 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of APBA3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:8,446,212...8,451,310
Ensembl chr 7:8,446,216...8,451,241
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G |
Aph1a |
aph-1 homolog A, gamma secretase subunit |
increases expression |
ISO |
zoledronic acid results in increased expression of APH1A mRNA |
CTD |
PMID:20977926 |
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NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955
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G |
Api5 |
apoptosis inhibitor 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of API5 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264
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G |
Arap1 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARAP1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184
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G |
Arhgap18 |
Rho GTPase activating protein 18 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARHGAP18 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
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G |
Arhgap19 |
Rho GTPase activating protein 19 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARHGAP19 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:240,571,554...240,617,361
Ensembl chr 1:240,580,871...240,617,287
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G |
Arhgap22 |
Rho GTPase activating protein 22 |
increases expression |
ISO |
zoledronic acid results in increased expression of ARHGAP22 mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548
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G |
Arhgap24 |
Rho GTPase activating protein 24 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARHGAP24 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
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G |
Arhgap26 |
Rho GTPase activating protein 26 |
increases expression |
ISO |
zoledronic acid results in increased expression of ARHGAP26 mRNA |
CTD |
PMID:24714768 |
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NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
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G |
Arhgap29 |
Rho GTPase activating protein 29 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGAP29 mRNA |
CTD |
PMID:16996129 |
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NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARHGDIA protein |
CTD |
PMID:28871336 |
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NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Arhgef12 |
Rho guanine nucleotide exchange factor 12 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF12 mRNA |
CTD |
PMID:16996129 |
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NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
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G |
Arhgef3 |
Rho guanine nucleotide exchange factor 3 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF3 mRNA |
CTD |
PMID:16996129 |
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NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
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G |
Arhgef4 |
Rho guanine nucleotide exchange factor 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARHGEF4 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075
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G |
Arid2 |
AT-rich interaction domain 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARID2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
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G |
Arl14 |
ARF like GTPase 14 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARL14 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:153,468,863...153,470,102
Ensembl chr 2:153,468,977...153,469,555
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G |
Arl4c |
ARF like GTPase 4C |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARL4C mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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G |
Arl5b |
ARF like GTPase 5B |
increases expression |
ISO |
zoledronic acid results in increased expression of ARL5B mRNA |
CTD |
PMID:20977926 |
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NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ARNT2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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G |
Arrdc3 |
arrestin domain containing 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of ARRDC3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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G |
Arrdc4 |
arrestin domain containing 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of ARRDC4 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
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G |
Asic1 |
acid sensing ion channel subunit 1 |
multiple interactions decreases expression |
ISO EXP |
zoledronic acid inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA] zoledronic acid results in decreased expression of ASIC1 mRNA |
CTD |
PMID:16769263 PMID:17323179 |
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NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ASNS mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Asphd2 |
aspartate beta-hydroxylase domain containing 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ASPHD2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr12:44,248,132...44,258,653
Ensembl chr12:44,248,145...44,257,772
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G |
Aspm |
assembly factor for spindle microtubules |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ASPM mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
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G |
Atf4 |
activating transcription factor 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATF4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of ATF5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Atg2a |
autophagy related 2A |
increases expression |
ISO |
zoledronic acid results in increased expression of ATG2A protein |
CTD |
PMID:28871336 |
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NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
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G |
Atoh8 |
atonal bHLH transcription factor 8 |
increases expression |
ISO |
zoledronic acid results in increased expression of ATOH8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
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G |
Atosa |
atos homolog A |
increases expression |
ISO |
Zoledronic Acid results in increased expression of ATOSA mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549
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G |
Atp10b |
ATPase phospholipid transporting 10B |
increases expression |
ISO |
zoledronic acid results in increased expression of ATP10B mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATP1A1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp6v0a4 |
ATPase H+ transporting V0 subunit a4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATP6V0A4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110
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G |
Atp6v1b1 |
ATPase H+ transporting V1 subunit B1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATP6V1B1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
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G |
Atp7b |
ATPase copper transporting beta |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATP7B mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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G |
Atrx |
ATRX, chromatin remodeler |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ATRX mRNA |
CTD |
PMID:20977926 |
|
NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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G |
Atxn1 |
ataxin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ATXN1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
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G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AURKB mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
Avpi1 |
arginine vasopressin-induced 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AVPI1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154
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G |
Axl |
Axl receptor tyrosine kinase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of AXL mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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G |
B3galt5 |
Beta-1,3-galactosyltransferase 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of B3GALT5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
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G |
Baat |
bile acid CoA:amino acid N-acyltransferase |
increases expression |
ISO |
zoledronic acid results in increased expression of BAAT mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions increases expression |
ISO |
[Tretinoin co-treated with zoledronic acid] results in increased expression of BAD protein zoledronic acid results in increased expression of BAD mRNA |
CTD |
PMID:19036117 PMID:20349282 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BAG1 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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G |
Bag3 |
BAG cochaperone 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of BAG3 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BASP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression multiple interactions increases expression |
ISO |
zoledronic acid results in decreased expression of BAX mRNA [Tretinoin co-treated with zoledronic acid] results in increased expression of BAX protein [zoledronic acid co-treated with Doxorubicin] results in increased expression of BAX protein zoledronic acid results in increased expression of BAX mRNA Zoledronic Acid results in increased expression of BAX mRNA |
CTD |
PMID:19036117 PMID:19789217 PMID:20349282 PMID:28871336 PMID:35587103 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbln |
bublin coiled coil protein |
increases expression |
ISO |
Zoledronic Acid results in increased expression of BBLN mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:15,674,577...15,677,322
Ensembl chr 3:15,674,580...15,677,374
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G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BBOX1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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G |
Bbx |
BBX high mobility group box domain containing |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BBX mRNA |
CTD |
PMID:20977926 |
|
NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
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|
G |
Bcap29 |
B-cell receptor-associated protein 29 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of BCAP29 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720
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G |
Bcar3 |
BCAR3 adaptor protein, NSP family member |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of BCAR3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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G |
Bche |
butyrylcholinesterase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BCHE mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases response to substance multiple interactions decreases expression affects expression increases expression |
ISO |
BCL2 protein results in decreased susceptibility to zoledronic acid [Tretinoin co-treated with zoledronic acid] results in decreased expression of BCL2 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of BCL2 protein zoledronic acid results in decreased expression of BCL2 mRNA zoledronic acid affects the expression of BCL2 mRNA Zoledronic Acid results in increased expression of BCL2 mRNA [zoledronic acid co-treated with Doxorubicin] results in decreased expression of BCL2 protein |
CTD |
PMID:11986784 PMID:18225567 PMID:19036117 PMID:19103299 PMID:19789217 PMID:20349282 PMID:24714768 PMID:28871336 PMID:35587103 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BCL2A1 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BCL2L1 mRNA |
CTD |
PMID:19036117 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Bcl2l10 |
Bcl2-like 10 |
affects expression |
ISO |
zoledronic acid affects the expression of BCL2L10 mRNA |
CTD |
PMID:19036117 |
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NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
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Bcl2l11 |
Bcl2-like 11 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNA |
CTD |
PMID:16996129 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Bcl2l15 |
Bcl2-like 15 |
increases expression |
ISO |
zoledronic acid results in increased expression of BCL2L15 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
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Bcl2l2 |
Bcl2-like 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of BCL2L2 mRNA |
CTD |
PMID:19036117 |
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NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
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G |
Becn1 |
beclin 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BECN1 protein |
CTD |
PMID:28871336 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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Bend5 |
BEN domain containing 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BEND5 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
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Bfsp1 |
beaded filament structural protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BFSP1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337
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Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
zoledronic acid results in increased expression of BGLAP mRNA |
CTD |
PMID:14751568 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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Bhlhe40 |
basic helix-loop-helix family, member e40 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of BHLHE40 mRNA |
CTD |
PMID:16996129 |
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NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bicdl1 |
BICD family like cargo adaptor 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BICDL1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130
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Bid |
BH3 interacting domain death agonist |
increases expression |
ISO |
zoledronic acid results in increased expression of BID mRNA |
CTD |
PMID:19036117 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
multiple interactions decreases expression |
ISO |
[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC2 mRNA zoledronic acid results in decreased expression of BIRC2 mRNA |
CTD |
PMID:19036117 PMID:20349282 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of BIRC3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions decreases expression |
ISO |
[Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 mRNA; [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 protein zoledronic acid results in decreased expression of BIRC5 mRNA; zoledronic acid results in decreased expression of BIRC5 protein |
CTD |
PMID:19036117 PMID:20349282 PMID:24714768 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Birc6 |
baculoviral IAP repeat-containing 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BIRC6 mRNA |
CTD |
PMID:19036117 |
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NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
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Bivm |
basic, immunoglobulin-like variable motif containing |
decreases expression |
ISO |
zoledronic acid results in decreased expression of BIVM mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:46,268,758...46,305,038
Ensembl chr 9:46,269,252...46,305,024
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Bloc1s5 |
biogenesis of lysosomal organelles complex 1 subunit 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of BLOC1S5 mRNA |
CTD |
PMID:20977926 |
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NCBI chr17:26,171,965...26,197,276
Ensembl chr17:26,172,018...26,197,251
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of BMAL1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmf |
Bcl2 modifying factor |
increases expression |
ISO |
zoledronic acid results in increased expression of BMF mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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G |
Bmp1 |
bone morphogenetic protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BMP1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of BMP2 mRNA |
CTD |
PMID:14751568 PMID:24714768 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmpr1a |
bone morphogenetic protein receptor type 1A |
increases expression |
ISO |
zoledronic acid results in increased expression of BMPR1A mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
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G |
Bmpr2 |
bone morphogenetic protein receptor type 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of BMPR2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
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G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of BNIP3 mRNA zoledronic acid results in increased expression of BNIP3 mRNA |
CTD |
PMID:19036117 PMID:25596134 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bnip5 |
BCL2 interacting protein 5 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of BNIP5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr20:6,957,736...6,975,062
Ensembl chr20:6,956,201...6,975,091
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G |
Bola2 |
bolA family member 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of BOLA2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
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G |
Bpgm |
bisphosphoglycerate mutase |
increases expression |
ISO |
zoledronic acid results in increased expression of BPGM mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
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G |
Brca2 |
BRCA2, DNA repair associated |
increases expression |
ISO |
zoledronic acid results in increased expression of BRCA2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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G |
Brip1 |
BRCA1 interacting DNA helicase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of BRIP1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
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G |
Btg2 |
BTG anti-proliferation factor 2 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of BTG2 mRNA zoledronic acid results in increased expression of BTG2 mRNA |
CTD |
PMID:20977926 PMID:25596134 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of BUB1 mRNA |
CTD |
PMID:16996129 |
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NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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G |
C13h1orf53 |
similar to human chromosome 1 open reading frame 53 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of C1ORF53 mRNA |
CTD |
PMID:24714768 |
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NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120
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G |
C14h4orf19 |
similar to human chromosome 4 open reading frame 19 |
increases expression |
ISO |
zoledronic acid results in increased expression of C4ORF19 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041
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G |
C14h7orf57 |
similar to human chromosome 7 open reading frame 57 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of C7ORF57 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:83,748,478...83,768,293
Ensembl chr14:83,748,478...83,767,435
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G |
C1ql4 |
complement C1q like 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of C1QL4 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678
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C1qtnf1 |
C1q and TNF related 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of C1QTNF1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
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C1qtnf6 |
C1q and TNF related 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of C1QTNF6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
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C1r |
complement C1r |
increases expression |
ISO |
zoledronic acid results in increased expression of C1R mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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G |
C1s |
complement C1s |
increases expression |
ISO |
zoledronic acid results in increased expression of C1S mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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G |
C20h6orf89 |
similar to human chromosome 6 open reading frame 89 |
increases expression |
ISO |
zoledronic acid results in increased expression of C6ORF89 mRNA |
CTD |
PMID:20977926 |
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NCBI chr20:7,322,483...7,362,054
Ensembl chr20:7,322,442...7,357,612
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G |
C2cd4a |
C2 calcium-dependent domain containing 4A |
increases expression |
ISO |
zoledronic acid results in increased expression of C2CD4A mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:68,467,017...68,469,781
Ensembl chr 8:68,466,664...68,470,031
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G |
C2cd4b |
C2 calcium-dependent domain containing 4B |
increases expression |
ISO |
zoledronic acid results in increased expression of NLF2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
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G |
C3 |
complement C3 |
increases expression |
ISO |
zoledronic acid results in increased expression of C3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C3h15orf48 |
similar to human chromosome 15 open reading frame 48 |
increases expression |
ISO |
zoledronic acid results in increased expression of C15ORF48 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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G |
C3h15orf62 |
similar to human chromosome 15 open reading frame 62 |
increases expression |
ISO |
zoledronic acid results in increased expression of C15ORF62 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:106,164,179...106,167,404
Ensembl chr 3:106,157,382...106,167,831
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C4bpa |
complement component 4 binding protein, alpha |
increases expression |
ISO |
zoledronic acid results in increased expression of C4BPA mRNA |
CTD |
PMID:24714768 |
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NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
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G |
C6h14orf132 |
similar to human chromosome 14 open reading frame 132 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of C14ORF132 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:124,365,466...124,398,449
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G |
Cacna2d3 |
calcium voltage-gated channel auxiliary subunit alpha2delta 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of CACNA2D3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
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G |
Cactin |
cactin, spliceosome C complex subunit |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CACTIN protein |
CTD |
PMID:28871336 |
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NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829
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G |
Calm1 |
calmodulin 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CALM1 protein |
CTD |
PMID:28871336 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Calml4 |
calmodulin-like 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CALML4 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234
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G |
Camk1d |
calcium/calmodulin-dependent protein kinase ID |
increases expression |
ISO |
zoledronic acid results in increased expression of CAMK1D mRNA |
CTD |
PMID:24714768 |
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NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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G |
Camk2d |
calcium/calmodulin-dependent protein kinase II delta |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAMK2D mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
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G |
Camk2n1 |
calcium/calmodulin-dependent protein kinase II inhibitor 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAMK2N1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
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G |
Camk4 |
calcium/calmodulin-dependent protein kinase IV |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAMK4 protein |
CTD |
PMID:28871336 |
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NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
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G |
Camsap1 |
calmodulin regulated spectrin-associated protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAMSAP1 protein |
CTD |
PMID:28871336 |
|
NCBI chr 3:8,746,176...8,806,067
Ensembl chr 3:8,746,176...8,806,072
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G |
Cant1 |
calcium activated nucleotidase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CANT1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAP2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
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G |
Capn13 |
calpain 13 |
increases expression |
ISO |
zoledronic acid results in increased expression of CAPN13 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:22,071,845...22,166,864
Ensembl chr 6:22,071,845...22,166,850
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G |
Capn6 |
calpain 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAPN6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr X:107,380,774...107,405,489
Ensembl chr X:107,380,774...107,405,489
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G |
Caprin1 |
cell cycle associated protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CAPRIN1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
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G |
Card10 |
caspase recruitment domain family, member 10 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CARD10 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
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G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of CARS1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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G |
Casp1 |
caspase 1 |
affects expression multiple interactions increases expression |
ISO |
zoledronic acid affects the expression of CASP1 mRNA [zoledronic acid co-treated with fluvastatin] results in increased expression of CASP1 mRNA zoledronic acid results in increased expression of CASP1 mRNA |
CTD |
PMID:16996129 PMID:19036117 PMID:24714768 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp14 |
caspase 14 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CASP14 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
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G |
Casp2 |
caspase 2 |
affects expression |
ISO |
zoledronic acid affects the expression of CASP2 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions decreases expression increases activity increases cleavage increases expression |
ISO |
[Tretinoin co-treated with zoledronic acid] results in increased activity of CASP3 protein; [vorinostat co-treated with zoledronic acid] results in increased activity of CASP3 protein; [zoledronic acid co-treated with arsenic trioxide] results in increased cleavage of CASP3 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of CASP3 protein; [zoledronic acid co-treated with Doxorubicin] results in increased expression of CASP3 protein; [zoledronic acid co-treated with Gossypol] results in increased activity of CASP3 protein; vorinostat promotes the reaction [zoledronic acid results in increased activity of CASP3 protein]; zoledronic acid results in increased cleavage of and results in increased activity of CASP3 protein; zoledronic acid results in increased expression of and results in increased activity of CASP3 protein zoledronic acid results in decreased expression of CASP3 protein [zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP3 protein zoledronic acid results in increased cleavage of CASP3 protein Zoledronic Acid results in increased expression of CASP3 mRNA |
CTD |
PMID:11986784 PMID:12796698 PMID:17070308 PMID:17562444 PMID:18025282 PMID:18695136 PMID:19036117 PMID:19789217 PMID:19825521 PMID:19915386 PMID:20349282 PMID:20977926 PMID:24714768 PMID:35587103 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of CASP4 mRNA |
CTD |
PMID:35587103 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
increases activity |
ISO |
zoledronic acid results in increased activity of CASP6 protein |
CTD |
PMID:17070308 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
multiple interactions increases activity |
ISO |
[Tretinoin co-treated with Zoledronic Acid] results in increased activity of CASP7 protein; [Zoledronic Acid co-treated with Gossypol] results in increased activity of CASP7 protein zoledronic acid results in increased activity of CASP7 protein |
CTD |
PMID:19825521 PMID:20349282 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
increases expression multiple interactions |
ISO |
zoledronic acid results in increased expression of CASP8 mRNA [zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP8 protein |
CTD |
PMID:19036117 PMID:19789217 PMID:20977926 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions affects expression |
ISO |
zoledronic acid results in increased activity of CASP9 protein [zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP9 protein zoledronic acid results in increased cleavage of and results in increased activity of CASP9 protein Zoledronic Acid affects the expression of CASP9 mRNA |
CTD |
PMID:12799645 PMID:19036117 PMID:19789217 PMID:35587103 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Casr |
calcium-sensing receptor |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CASR mRNA |
CTD |
PMID:24714768 |
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NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
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G |
Castor1 |
cytosolic arginine sensor for mTORC1 subunit 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CASTOR1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
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G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CAVIN2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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G |
Cbr1 |
carbonyl reductase 1 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of CBR1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Cbs |
cystathionine beta synthase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CBS mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Cbx5 |
chromobox 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of CBX5 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
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G |
Cc2d2a |
coiled-coil and C2 domain containing 2A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CC2D2A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
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G |
Ccdc138 |
coiled-coil domain containing 138 |
increases expression |
ISO |
zoledronic acid results in increased expression of CCDC138 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr20:26,493,624...26,572,367
Ensembl chr20:26,495,235...26,572,376
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
zoledronic acid promotes the reaction [Gossypol results in decreased expression of CCL2 mRNA] zoledronic acid results in increased expression of CCL2 mRNA |
CTD |
PMID:19825521 PMID:24714768 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
zoledronic acid results in increased expression of CCL20 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl28 |
C-C motif chemokine ligand 28 |
increases expression |
ISO |
zoledronic acid results in increased expression of CCL28 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions decreases expression |
ISO |
CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein] Zoledronic Acid results in decreased expression of CCN1 mRNA; Zoledronic Acid results in decreased expression of CCN1 protein |
CTD |
PMID:19530242 |
|
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CCNA2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions decreases expression |
ISO |
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 protein zoledronic acid results in decreased expression of CCNB1 mRNA |
CTD |
PMID:19789217 PMID:20977926 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CCNB2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
ISO |
zoledronic acid results in decreased expression of CCND1 mRNA [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND1 protein zoledronic acid results in decreased expression of CCND1 protein |
CTD |
PMID:16621245 PMID:19789217 PMID:24714768 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd3 |
cyclin D3 |
multiple interactions decreases expression |
ISO |
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND3 protein zoledronic acid results in decreased expression of CCND3 protein |
CTD |
PMID:19789217 |
|
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNE1 protein |
CTD |
PMID:19789217 |
|
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccne2 |
cyclin E2 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of CCNE2 mRNA zoledronic acid results in increased expression of CCNE2 mRNA |
CTD |
PMID:20977926 PMID:25596134 |
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NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD14 mRNA; zoledronic acid results in increased expression of CD14 protein |
CTD |
PMID:24714768 PMID:28871336 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd27 |
CD27 molecule |
affects expression |
ISO |
zoledronic acid affects the expression of CD27 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
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G |
Cd34 |
CD34 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD34 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD40 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CD40LG mRNA |
CTD |
PMID:19036117 |
|
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD44 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
increases expression |
ISO |
zoledronic acid results in increased expression of CD55 mRNA; zoledronic acid results in increased expression of CD55 protein |
CTD |
PMID:20977926 PMID:24714768 PMID:28871336 |
|
NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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G |
Cd59b |
CD59b molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD59 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD68 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cd69 |
Cd69 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD69 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd74 |
CD74 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD74 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD80 protein |
CTD |
PMID:19446661 |
|
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD83 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
zoledronic acid results in increased expression of CD86 protein |
CTD |
PMID:19446661 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc14a |
cell division cycle 14A |
increases expression |
ISO |
zoledronic acid results in increased expression of CDC14A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDC20 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc25c |
cell division cycle 25C |
increases expression |
ISO |
zoledronic acid results in increased expression of CDC25C mRNA |
CTD |
PMID:20977926 |
|
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc26 |
cell division cycle 26 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDC26 protein |
CTD |
PMID:28871336 |
|
NCBI chr 5:75,844,852...75,859,830
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G |
Cdc42 |
cell division cycle 42 |
multiple interactions |
ISO |
zoledronic acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein] zoledronic acid results in increased expression of [CDC42 protein binds to Guanosine Triphosphate]; zoledronic acid results in increased expression of and affects the localization of CDC42 protein |
CTD |
PMID:16734383 PMID:28871336 |
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NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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G |
Cdc42ep2 |
CDC42 effector protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of CDC42EP2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
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G |
Cdc42ep5 |
CDC42 effector protein 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of CDC42EP5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:70,035,921...70,038,990
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G |
Cdc45 |
cell division cycle 45 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of CDC45 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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G |
Cdca5 |
cell division cycle associated 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of CDCA5 protein |
CTD |
PMID:28871336 |
|
NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
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G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDCA7 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdca8 |
cell division cycle associated 8 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDCA8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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G |
Cdh4 |
cadherin 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of CDH4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDK1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK2 protein |
CTD |
PMID:19789217 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of CDK2AP2 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK4 protein |
CTD |
PMID:19789217 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein] zoledronic acid results in increased expression of CDKN1A protein |
CTD |
PMID:19530242 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
ISO |
[Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein; Gefitinib promotes the reaction [[Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein] |
CTD |
PMID:16322342 PMID:19530242 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
increases expression |
ISO |
zoledronic acid results in increased expression of CDKN1C mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2aip |
CDKN2A interacting protein |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDKN2AIP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
increases expression |
ISO |
zoledronic acid results in increased expression of CDKN2B mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDKN3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cdt1 |
chromatin licensing and DNA replication factor 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CDT1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
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G |
Cdv3 |
carnitine deficiency-associated gene expressed in ventricle 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of CDV3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:103,934,006...103,947,173
Ensembl chr 8:103,933,996...103,947,192
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G |
Ceacam6 |
CEA cell adhesion molecule 6 |
increases expression |
ISO |
zoledronic acid results in increased expression of CEACAM6 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
increases expression |
ISO |
zoledronic acid results in increased expression of CEBPA mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
zoledronic acid results in increased expression of CEBPB mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
increases expression |
ISO |
zoledronic acid results in increased expression of CEBPD mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CENPA mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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G |
Cenpf |
centromere protein F |
decreases expression decreases farnesylation |
ISO |
zoledronic acid results in decreased expression of CENPF mRNA zoledronic acid results in decreased farnesylation of CENPF protein |
CTD |
PMID:20015195 PMID:24714768 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Cenpi |
centromere protein I |
increases expression |
ISO |
zoledronic acid results in increased expression of CENPI mRNA |
CTD |
PMID:20977926 |
|
NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657
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G |
Cenpm |
centromere protein M |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CENPM mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258
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G |
Cep120 |
centrosomal protein 120 |
increases expression |
ISO |
zoledronic acid results in increased expression of CEP120 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964
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G |
Cep20 |
centrosomal protein 20 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of CEP20 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837
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G |
Cep295 |
centrosomal protein 295 |
increases expression |
ISO |
zoledronic acid results in increased expression of CEP295 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552
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G |
Cep55 |
centrosomal protein 55 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CEP55 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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G |
Cep57 |
centrosomal protein 57 |
increases expression |
ISO |
zoledronic acid results in increased expression of CEP57 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249
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G |
Cept1 |
choline/ethanolamine phosphotransferase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CEPT1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
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G |
Cfb |
complement factor B |
increases expression |
ISO |
zoledronic acid results in increased expression of CFB mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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G |
Cfl1 |
cofilin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CFL1 protein |
CTD |
PMID:28871336 |
|
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
zoledronic acid results in increased expression of CFLAR mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Cgn |
cingulin |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CGN mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
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G |
Cgnl1 |
cingulin-like 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CGNL1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CHAC1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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G |
Chmp4b |
charged multivesicular body protein 4B |
increases expression |
ISO |
zoledronic acid results in increased expression of CHMP4B mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
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G |
Chmp6 |
charged multivesicular body protein 6 |
increases expression |
ISO |
zoledronic acid results in increased expression of CHMP6 protein |
CTD |
PMID:28871336 |
|
NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640
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G |
Chst4 |
carbohydrate sulfotransferase 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of CHST4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:37,993,471...38,002,123
Ensembl chr19:37,991,417...38,003,608
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G |
Ciita |
class II, major histocompatibility complex, transactivator |
increases expression |
ISO |
zoledronic acid results in increased expression of CIITA mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
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G |
Cimip2c |
ciliary microtubule inner protein 2C |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of CIMIP2C mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:25,905,294...25,923,615
Ensembl chr 6:25,905,294...25,923,615
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G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of CKS2 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr17:13,570,611...13,575,770
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G |
Clcn5 |
chloride voltage-gated channel 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CLCN5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264
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G |
Clcnka |
chloride voltage-gated channel Ka |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CLCNKA mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
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G |
Clcnkb |
chloride voltage-gated channel Kb |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CLCNKB mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
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G |
Cldn14 |
claudin 14 |
increases expression |
ISO |
zoledronic acid results in increased expression of CLDN14 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
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G |
Cldn16 |
claudin 16 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CLDN16 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:74,290,298...74,309,588
Ensembl chr11:74,290,298...74,309,588
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G |
Cldn2 |
claudin 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CLDN2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
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G |
Cldn3 |
claudin 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of CLDN3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
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G |
Clec4e |
C-type lectin domain family 4, member E |
increases expression |
ISO |
zoledronic acid results in increased expression of CLEC4E mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
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|
G |
Cln3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
increases expression |
ISO |
zoledronic acid results in increased expression of CLN3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
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G |
Cngb1 |
cyclic nucleotide gated channel subunit beta 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CNGB1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173
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G |
Cntnap1 |
contactin associated protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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G |
Col16a1 |
collagen type XVI alpha 1 chain |
increases expression |
ISO |
zoledronic acid results in increased expression of COL16A1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825
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G |
Col18a1 |
collagen type XVIII alpha 1 chain |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COL18A1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression multiple interactions increases expression |
ISO |
zoledronic acid results in decreased expression of COL1A1 mRNA; zoledronic acid results in decreased expression of COL1A1 protein Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:19597852 PMID:28871336 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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|
G |
Col3a1 |
collagen type III alpha 1 chain |
increases expression multiple interactions |
ISO |
zoledronic acid results in increased expression of COL3A1 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA] |
CTD |
PMID:28871336 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
|
|
G |
Col4a1 |
collagen type IV alpha 1 chain |
increases expression multiple interactions |
ISO |
zoledronic acid results in increased expression of COL4A1 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:28871336 |
|
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
|
|
G |
Col4a3 |
collagen type IV alpha 3 chain |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COL4A3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
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G |
Col4a5 |
collagen type IV alpha 5 chain |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COL4A5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692
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|
G |
Col5a1 |
collagen type V alpha 1 chain |
increases expression |
ISO |
zoledronic acid results in increased expression of COL5A1 protein |
CTD |
PMID:28871336 |
|
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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|
G |
Col9a2 |
collagen type IX alpha 2 chain |
increases expression |
ISO |
zoledronic acid results in increased expression of COL9A2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677
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G |
Comp |
cartilage oligomeric matrix protein |
increases expression |
ISO |
zoledronic acid results in increased expression of COMP protein |
CTD |
PMID:28871336 |
|
NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
|
|
G |
Coq3 |
coenzyme Q3 methyltransferase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COQ3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
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G |
Coq4 |
coenzyme Q4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COQ4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
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G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of COX17 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr11:62,400,733...62,406,507
|
|
G |
Cp |
ceruloplasmin |
increases expression |
ISO |
zoledronic acid results in increased expression of CP mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Cpa4 |
carboxypeptidase A4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CPA4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255
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|
G |
Cpd |
carboxypeptidase D |
increases expression |
ISO |
zoledronic acid results in increased expression of CPD mRNA |
CTD |
PMID:20977926 |
|
NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
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|
G |
Cpeb2 |
cytoplasmic polyadenylation element binding protein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CPEB2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
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G |
Cpne3 |
copine 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of CPNE3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
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|
G |
Cpne8 |
copine 8 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CPNE8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
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|
G |
Cpq |
carboxypeptidase Q |
decreases expression |
ISO |
zoledronic acid results in decreased expression of PGCP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
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|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
decreases expression multiple interactions |
ISO |
zoledronic acid results in decreased expression of CPT1A mRNA; zoledronic acid results in decreased expression of CPT1A protein Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA] |
CTD |
PMID:28871336 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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|
G |
Cpt2 |
carnitine palmitoyltransferase 2 |
decreases expression multiple interactions |
ISO |
zoledronic acid results in decreased expression of CPT2 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA] |
CTD |
PMID:28871336 |
|
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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|
G |
Cpvl |
carboxypeptidase, vitellogenic-like |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CPVL mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655
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|
G |
Crat |
carnitine O-acetyltransferase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CRAT mRNA |
CTD |
PMID:28871336 |
|
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
|
|
G |
Creb5 |
cAMP responsive element binding protein 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CREB5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
|
|
G |
Crls1 |
cardiolipin synthase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CRLS1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
|
|
G |
Cryab |
crystallin, alpha B |
increases expression |
ISO |
zoledronic acid results in increased expression of CRYAB mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
|
|
G |
Csf1 |
colony stimulating factor 1 |
increases expression decreases expression |
ISO |
zoledronic acid results in increased expression of CSF1 mRNA zoledronic acid results in decreased expression of CSF1 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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|
G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of CSF2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
|
|
G |
Csrp2 |
cysteine and glycine-rich protein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CSRP2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
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|
G |
Cst3 |
cystatin C |
increases expression |
ISO |
zoledronic acid results in increased expression of CST3 protein |
CTD |
PMID:28871336 |
|
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
|
|
G |
Ctbs |
chitobiase |
increases expression |
ISO |
zoledronic acid results in increased expression of CTBS mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 2:235,340,520...235,355,091
Ensembl chr 2:235,340,547...235,355,091
|
|
G |
Cth |
cystathionine gamma-lyase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CTH mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
|
|
G |
Ctsb |
cathepsin B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CTSB protein |
CTD |
PMID:16475674 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
|
|
G |
Ctsc |
cathepsin C |
increases expression |
ISO |
zoledronic acid results in increased expression of CTSC mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
|
|
G |
Ctse |
cathepsin E |
increases expression |
ISO |
zoledronic acid results in increased expression of CTSE mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
|
|
G |
Ctss |
cathepsin S |
increases expression |
ISO |
zoledronic acid results in increased expression of CTSS mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
|
|
G |
Cttn |
cortactin |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CTTN mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
|
|
G |
Ctu2 |
cytosolic thiouridylase subunit 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CTU2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623
|
|
G |
Cubn |
cubilin |
increases expression |
ISO |
zoledronic acid results in increased expression of CUBN mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
|
|
G |
Cul4a |
cullin 4A |
increases expression |
ISO |
zoledronic acid results in increased expression of CUL4A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
|
|
G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CX3CL1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
|
|
G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
[zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA zoledronic acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:19825521 PMID:24714768 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
zoledronic acid results in increased expression of CXCL10 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
|
|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CXCL12 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CXCL14 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
|
|
G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
increases expression |
ISO |
zoledronic acid results in increased expression of CXCL16 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of CXCL2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA zoledronic acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:19825521 PMID:24714768 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of CXCR4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyb5r3 |
cytochrome b5 reductase 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYB5R3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
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G |
Cycs |
cytochrome c, somatic |
increases expression |
ISO |
Zoledronic Acid results in increased expression of CYCS mRNA |
CTD |
PMID:35587103 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyfip2 |
cytoplasmic FMR1 interacting protein 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CYFIP2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP1A1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP1A2 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP1B1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP3A5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp4b1 |
cytochrome P450, family 4, subfamily b, polypeptide 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP4B1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
zoledronic acid results in increased expression of CYP51A1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
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G |
Cys1 |
cystin 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of CYS1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:41,300,836...41,318,071
Ensembl chr 6:41,300,836...41,318,071
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G |
Cytip |
cytohesin 1 interacting protein |
increases expression |
ISO |
zoledronic acid results in increased expression of CYTIP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
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G |
Dapk1 |
death associated protein kinase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DAPK1 mRNA |
CTD |
PMID:19036117 |
|
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dapp1 |
dual adaptor of phosphotyrosine and 3-phosphoinositides 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of DAPP1 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423
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G |
Dcaf15 |
DDB1 and CUL4 associated factor 15 |
increases expression |
ISO |
zoledronic acid results in increased expression of DCAF15 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277
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G |
Dcdc2 |
doublecortin domain containing 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DCDC2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
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G |
Dcun1d4 |
defective in cullin neddylation 1 domain containing 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of DCUN1D4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207
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G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DDAH1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of DDIT3 mRNA |
CTD |
PMID:35587103 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DDIT4 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
ISO |
zoledronic acid results in increased expression of DDIT4L mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
increases expression decreases expression |
ISO |
zoledronic acid results in increased expression of DDR1 mRNA zoledronic acid monohydrate decreases expression of DDR1 mRNA and protein in human PC3 cancer cell line |
CTD RGD |
PMID:24714768 PMID:26366216 |
RGD:151347692 |
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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G |
Ddx10 |
DEAD-box helicase 10 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DDX10 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
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G |
Ddx42 |
DEAD-box helicase 42 |
increases expression |
ISO |
zoledronic acid results in increased expression of DDX42 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939
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G |
Defb1 |
defensin beta 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of DEFB1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
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G |
Defb5 |
defensin beta 5 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of DEFB4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
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|
G |
Dennd2a |
DENN domain containing 2A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DENND2A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:68,233,016...68,332,235
Ensembl chr 4:68,233,958...68,332,105
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G |
Dennd2b |
DENN domain containing 2B |
increases expression |
ISO |
Zoledronic Acid results in increased expression of DENND2B mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680
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G |
Dennd2d |
DENN domain containing 2D |
increases expression |
ISO |
zoledronic acid results in increased expression of DENND2D mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
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G |
Depdc1 |
DEP domain containing 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DEPDC1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
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G |
Depp1 |
DEPP autophagy regulator 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of DEPP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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G |
Deptor |
DEP domain containing MTOR-interacting protein |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of DEPTOR mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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G |
Dffa |
DNA fragmentation factor subunit alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DFFA mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
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|
G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
zoledronic acid results in increased expression of DHCR7 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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|
G |
Dhrs11 |
dehydrogenase/reductase 11 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DHRS11 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
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G |
Dhrs3 |
dehydrogenase/reductase 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DHRS3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
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G |
Dhx35 |
DEAH-box helicase 35 |
increases expression |
ISO |
zoledronic acid results in increased expression of DHX35 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
multiple interactions |
ISO |
[Tretinoin co-treated with zoledronic acid] results in decreased expression of DIABLO protein |
CTD |
PMID:20349282 |
|
NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Diaph3 |
diaphanous-related formin 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DIAPH3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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G |
Dio2 |
iodothyronine deiodinase 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DIO2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DKK1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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|
G |
Dlc1 |
DLC1 Rho GTPase activating protein |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DLC1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of DLG1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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G |
Dlgap4 |
DLG associated protein 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DLGAP4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490
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G |
Dlgap5 |
DLG associated protein 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DLGAP5 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dlx1 |
distal-less homeobox 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DLX1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
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|
G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
zoledronic acid results in increased expression of DNAJB9 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnase1l1 |
deoxyribonuclease 1-like 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of DNASE1L1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr X:152,056,942...152,065,518
Ensembl chr X:152,056,942...152,065,518
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G |
Dner |
delta/notch-like EGF repeat containing |
increases expression |
ISO |
zoledronic acid results in increased expression of DNER mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
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G |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
zoledronic acid results in increased expression of DOCK10 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
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G |
Dpp9 |
dipeptidyl peptidase 9 |
increases expression |
ISO |
zoledronic acid results in increased expression of DPP9 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541
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G |
Dse |
dermatan sulfate epimerase |
increases expression |
ISO |
zoledronic acid results in increased expression of DSE mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
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G |
Dsel |
dermatan sulfate epimerase-like |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DSEL mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
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G |
Dtwd2 |
DTW domain containing 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DTWD2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832
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G |
Dtx3 |
deltex E3 ubiquitin ligase 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of DTX3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
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G |
Dusp18 |
dual specificity phosphatase 18 |
increases expression |
ISO |
zoledronic acid results in increased expression of DUSP18 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr14:78,790,183...78,811,576
Ensembl chr14:78,787,505...78,811,576
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G |
Dusp4 |
dual specificity phosphatase 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DUSP4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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|
G |
Dusp5 |
dual specificity phosphatase 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DUSP5 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DUSP6 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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|
G |
Dync2li1 |
dynein cytoplasmic 2 light intermediate chain 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of DYNC2LI1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:9,992,537...10,025,355
Ensembl chr 6:9,992,541...10,025,336
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G |
E2f2 |
E2F transcription factor 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of E2F2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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G |
Ebi3 |
Epstein-Barr virus induced 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of EBI3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
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G |
Ebp |
EBP, cholestenol delta-isomerase |
increases expression |
ISO |
zoledronic acid results in increased expression of EBP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Ece1 |
endothelin converting enzyme 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ECE1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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|
G |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ECH1 mRNA |
CTD |
PMID:28871336 |
|
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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|
G |
Ecm1 |
extracellular matrix protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ECM1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
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|
G |
Edn1 |
endothelin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of EDN1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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|
G |
Efhd1 |
EF-hand domain family, member D1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EFHD1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
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|
G |
Efna1 |
ephrin A1 |
increases expression |
ISO |
zoledronic acid results in increased expression of EFNA1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
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|
G |
Efnb2 |
ephrin B2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EFNB2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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|
G |
Egfl6 |
EGF-like-domain, multiple 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EGFL6 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044
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|
G |
Egln2 |
egl-9 family hypoxia-inducible factor 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of EGLN2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
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|
G |
Egr1 |
early growth response 1 |
increases expression decreases expression |
ISO |
zoledronic acid results in increased expression of EGR1 mRNA zoledronic acid results in decreased expression of EGR1 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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|
G |
Egr2 |
early growth response 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of EGR2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Egr4 |
early growth response 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of EGR4 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EHHADH mRNA |
CTD |
PMID:28871336 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G |
Elk1 |
ETS transcription factor ELK1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ELK1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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G |
Ell2 |
elongation factor for RNA polymerase II 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ELL2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
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G |
Elob |
elongin B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ELOB mRNA |
CTD |
PMID:24714768 |
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NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
zoledronic acid results in increased expression of ELOVL6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Eml4 |
EMAP like 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of EML4 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
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G |
Emp3 |
epithelial membrane protein 3 |
multiple interactions increases expression |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of EMP3 mRNA zoledronic acid results in increased expression of EMP3 mRNA |
CTD |
PMID:16996129 PMID:20977926 |
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NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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G |
Enpp6 |
ectonucleotide pyrophosphatase/phosphodiesterase 6 |
increases expression |
ISO |
zoledronic acid results in increased expression of ENPP6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
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G |
Ep400 |
E1A binding protein p400 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EP400 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
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G |
Epha4 |
Eph receptor A4 |
increases expression |
ISO |
zoledronic acid results in increased expression of EPHA4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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G |
Ephb3 |
Eph receptor B3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EPHB3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370
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G |
Ephb4 |
EPH receptor B4 |
multiple interactions |
ISO |
[zoledronic acid co-treated with Gossypol] results in decreased expression of EPHB4 mRNA |
CTD |
PMID:19825521 |
|
NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314
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G |
Ephx2 |
epoxide hydrolase 2 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of EPHX2 mRNA zoledronic acid results in increased expression of EPHX2 protein |
CTD |
PMID:24714768 PMID:28871336 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zoledronic Acid results in decreased expression of EPRS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Epsti1 |
epithelial stromal interaction 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of EPSTI1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
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G |
Ercc5 |
ERCC excision repair 5, endonuclease |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of ERCC5 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
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G |
Erg |
ETS transcription factor ERG |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of ERG mRNA |
CTD |
PMID:16996129 |
|
NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871
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G |
Ergic2 |
ERGIC and golgi 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ERGIC2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:181,090,808...181,123,060
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G |
Erlin1 |
ER lipid raft associated 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ERLIN1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of ERN1 mRNA; Zoledronic Acid results in increased expression of ERN1 protein |
CTD |
PMID:35587103 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
ISO |
Zoledronic Acid results in increased expression of ERO1A mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
Erp27 |
endoplasmic reticulum protein 27 |
increases expression |
ISO |
zoledronic acid results in increased expression of ERP27 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660
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G |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ESCO2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
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G |
Esrrg |
estrogen-related receptor gamma |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ESRRG mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
increases expression |
ISO |
zoledronic acid results in increased expression of ETS1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ETS2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
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G |
Etv4 |
ETS variant transcription factor 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ETV4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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G |
Eva1a |
eva-1 homolog A, regulator of programmed cell death |
decreases expression |
ISO |
zoledronic acid results in decreased expression of EVA1A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011
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G |
Exoc5 |
exocyst complex component 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of EXOC5 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr15:22,310,682...22,355,695
Ensembl chr15:22,308,946...22,355,335
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G |
Ezr |
ezrin |
increases expression |
ISO |
zoledronic acid results in increased expression of EZR mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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G |
F3 |
coagulation factor III, tissue factor |
decreases expression |
ISO |
zoledronic acid results in decreased expression of F3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp1 |
fatty acid binding protein 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of FABP1 mRNA |
CTD |
PMID:35587103 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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|
G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO |
[Tretinoin co-treated with zoledronic acid] results in increased expression of FADD protein |
CTD |
PMID:20349282 |
|
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads2 |
fatty acid desaturase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of FADS2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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G |
Fads3 |
fatty acid desaturase 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of FADS3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
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G |
Fam107a |
family with sequence similarity 107, member A |
increases expression |
ISO |
zoledronic acid results in increased expression of FAM107A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
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G |
Fam167a |
family with sequence similarity 167, member A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FAM167A mRNA |
CTD |
PMID:25596134 |
|
NCBI chr15:37,685,221...37,715,472
Ensembl chr15:37,700,919...37,715,469
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G |
Fam171b |
family with sequence similarity 171, member B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FAM171B mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
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G |
Fam20a |
FAM20A, golgi associated secretory pathway pseudokinase |
increases expression |
ISO |
zoledronic acid results in increased expression of FAM20A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672
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G |
Fam222b |
family with sequence similarity 222, member B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FAM222B mRNA |
CTD |
PMID:20977926 |
|
NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350
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G |
Fam43a |
family with sequence similarity 43, member A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FAM43A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
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G |
Fas |
Fas cell surface death receptor |
increases expression multiple interactions |
ISO |
zoledronic acid results in increased expression of FAS mRNA [Tretinoin co-treated with zoledronic acid] results in increased expression of FAS protein |
CTD |
PMID:19036117 PMID:20349282 PMID:25596134 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
affects expression |
ISO |
zoledronic acid affects the expression of FASLG mRNA |
CTD |
PMID:19036117 |
|
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fblim1 |
filamin binding LIM protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FBLIM1 protein |
CTD |
PMID:28871336 |
|
NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
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G |
Fbln1 |
fibulin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FBLN1 mRNA; zoledronic acid results in increased expression of FBLN1 protein |
CTD |
PMID:24714768 PMID:28871336 |
|
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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G |
Fbln5 |
fibulin 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of FBLN5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755
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G |
Fbn1 |
fibrillin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FBN1 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
|
NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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G |
Fcgbp |
Fc gamma binding protein |
increases expression |
ISO |
zoledronic acid results in increased expression of FCGBP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083
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G |
Fcgrt |
Fc gamma receptor and transporter |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FCGRT mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
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G |
Fcmr |
Fc mu receptor |
increases expression |
ISO |
zoledronic acid results in increased expression of FCMR mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
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G |
Fcrl2 |
Fc receptor-like 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of FCRL2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
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G |
Fcrla |
Fc receptor-like A |
increases expression |
ISO |
zoledronic acid results in increased expression of FCRLA mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:83,160,453...83,170,170
Ensembl chr13:83,160,398...83,170,762
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
multiple interactions increases expression |
ISO EXP |
[zoledronic acid co-treated with fluvastatin] results in increased expression of FDFT1 mRNA zoledronic acid results in increased expression of FDFT1 mRNA |
CTD |
PMID:16996129 PMID:18325729 |
|
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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G |
Fdps |
farnesyl diphosphate synthase |
affects binding decreases activity multiple interactions increases activity increases expression |
ISO EXP |
zoledronic acid binds to FDPS protein zoledronic acid results in decreased activity of FDPS protein [zoledronic acid results in decreased activity of FDPS protein] which results in increased abundance of isopentenyl pyrophosphate zoledronic acid results in increased activity of FDPS protein zoledronic acid results in increased expression of FDPS mRNA |
CTD |
PMID:11160603 PMID:12846887 PMID:16684881 PMID:17208200 PMID:18325729 PMID:19621390 PMID:19699819 PMID:24714768 More...
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NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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G |
Fech |
ferrochelatase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FECH mRNA |
CTD |
PMID:24714768 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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G |
Fem1b |
fem-1 homolog B |
increases expression |
ISO |
zoledronic acid results in increased expression of FEM1B mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
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G |
Fez1 |
fasciculation and elongation protein zeta 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FEZ1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
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G |
Fgf18 |
fibroblast growth factor 18 |
increases expression |
ISO |
zoledronic acid results in increased expression of FGF18 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression multiple interactions |
ISO |
zoledronic acid results in decreased expression of FGF2 mRNA zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGF2 mRNA] |
CTD |
PMID:19825521 PMID:24714768 |
|
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf9 |
fibroblast growth factor 9 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FGF9 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfbp1 |
fibroblast growth factor binding protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FGFBP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
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|
G |
Fgfr3 |
fibroblast growth factor receptor 3 |
multiple interactions decreases expression |
ISO |
zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGFR3 mRNA] zoledronic acid results in decreased expression of FGFR3 mRNA |
CTD |
PMID:19825521 PMID:24714768 |
|
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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|
G |
Fgfr4 |
fibroblast growth factor receptor 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FGFR4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
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G |
Fgl2 |
fibrinogen-like 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FGL2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
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G |
Fhl1 |
four and a half LIM domains 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FHL1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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G |
Fhl2 |
four and a half LIM domains 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FHL2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
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G |
Fignl1 |
fidgetin-like 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FIGNL1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
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G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FILIP1L mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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G |
Fjx1 |
four-jointed box kinase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FJX1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
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|
G |
Fkbp1a |
FKBP prolyl isomerase 1A |
increases expression |
ISO |
zoledronic acid results in increased expression of FKBP1A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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G |
Fmnl3 |
formin-like 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of FMNL3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626
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G |
Fn1 |
fibronectin 1 |
multiple interactions increases expression |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased expression of FN1 protein] Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of FN1 protein]; SLC27A2 gene mutant form inhibits the reaction [Zoledronic Acid results in increased expression of FN1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [Zoledronic Acid results in increased expression of FN1 protein] zoledronic acid results in increased expression of FN1 mRNA; zoledronic acid results in increased expression of FN1 protein |
CTD |
PMID:28871336 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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|
G |
Fnbp1 |
formin binding protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FNBP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881
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|
G |
Fnta |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of FNTA mRNA |
CTD |
PMID:16996129 |
|
NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
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|
G |
Folr1 |
folate receptor alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FOLR1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression multiple interactions |
ISO EXP |
zoledronic acid results in decreased expression of FOS mRNA zoledronic acid results in decreased expression of FOS protein zoledronic acid inhibits the reaction [Freund's Adjuvant results in increased expression of FOS protein] |
CTD |
PMID:16769263 PMID:17323179 PMID:24714768 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Foxj1 |
forkhead box J1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FOXJ1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237
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|
G |
Foxo1 |
forkhead box O1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FOXO1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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|
G |
Frem2 |
FRAS1 related extracellular matrix 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FREM2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785
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|
G |
Frk |
fyn-related Src family tyrosine kinase |
increases expression |
ISO |
zoledronic acid results in increased expression of FRK mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
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|
G |
Fscn1 |
fascin actin-bundling protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FSCN1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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|
G |
Fsd1l |
fibronectin type III and SPRY domain containing 1-like |
increases expression |
ISO |
zoledronic acid results in increased expression of FSD1L mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928
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|
G |
Fstl1 |
follistatin-like 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FSTL1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
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|
G |
Fstl3 |
follistatin like 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FSTL3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
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|
G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FTH1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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|
G |
Fuca1 |
alpha-L-fucosidase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of FUCA1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
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|
G |
Fut8 |
fucosyltransferase 8 |
increases expression |
ISO |
zoledronic acid results in increased expression of FUT8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677
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|
G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FXYD2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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|
G |
Fyb1 |
FYN binding protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of FYB1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
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|
G |
Fzd5 |
frizzled class receptor 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of FZD5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457
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|
G |
Gabarapl1 |
GABA type A receptor associated protein like 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GABARAPL1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
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|
G |
Gabrp |
gamma-aminobutyric acid type A receptor subunit pi |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GABRP mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
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|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GADD45A mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
multiple interactions increases expression |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of GADD45B mRNA zoledronic acid results in increased expression of GADD45B mRNA |
CTD |
PMID:16996129 PMID:20977926 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
ISO |
zoledronic acid results in increased expression of GADD45G mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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|
G |
Galnt10 |
polypeptide N-acetylgalactosaminyltransferase 10 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GALNT10 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013
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|
G |
Galnt11 |
polypeptide N-acetylgalactosaminyltransferase 11 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GALNT11 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
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|
G |
Galnt16 |
polypeptide N-acetylgalactosaminyltransferase 16 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GALNT16 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
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|
G |
Galnt18 |
polypeptide N-acetylgalactosaminyltransferase 18 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of GALNT18 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268
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|
G |
Gbp2 |
guanylate binding protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GBP2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
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|
G |
Gbp4 |
guanylate binding protein 4 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of GBP4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
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|
G |
Gbp5 |
guanylate binding protein 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of GBP5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
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|
G |
Gc |
GC, vitamin D binding protein |
increases expression |
ISO |
zoledronic acid results in increased expression of GC protein |
CTD |
PMID:28871336 |
|
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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|
G |
Gcnt1 |
glucosaminyl (N-acetyl) transferase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GCNT1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
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|
G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
zoledronic acid results in increased expression of GCNT3 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
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|
G |
Gdf15 |
growth differentiation factor 15 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GDF15 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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|
G |
Gdi2 |
GDP dissociation inhibitor 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GDI2 protein |
CTD |
PMID:28871336 |
|
NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
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|
G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GEM mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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|
G |
Ggps1 |
geranylgeranyl diphosphate synthase 1 |
decreases activity |
ISO |
zoledronic acid results in decreased activity of GGPS1 protein |
CTD |
PMID:17208200 |
|
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GGT1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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|
G |
Gins2 |
GINS complex subunit 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GINS2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
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|
G |
Gjb1 |
gap junction protein, beta 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GJB1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GJB2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
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|
G |
Gk |
glycerol kinase |
increases expression |
ISO |
zoledronic acid results in increased expression of GK mRNA |
CTD |
PMID:20977926 |
|
NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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|
G |
Gla |
galactosidase, alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GLA protein |
CTD |
PMID:28871336 |
|
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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|
G |
Glce |
glucuronic acid epimerase |
increases expression |
ISO |
zoledronic acid results in increased expression of GLCE mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
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|
G |
Glg1 |
golgi glycoprotein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GLG1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
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|
G |
Glipr1 |
GLI pathogenesis-related 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GLIPR1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
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|
G |
Glrx3 |
glutaredoxin 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GLRX3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
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|
G |
Gnb2 |
G protein subunit beta 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GNB2 protein |
CTD |
PMID:28871336 |
|
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
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|
G |
Gnb4 |
G protein subunit beta 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of GNB4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
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|
G |
Gng10 |
G protein subunit gamma 10 |
increases expression |
ISO |
zoledronic acid results in increased expression of GNG10 protein |
CTD |
PMID:28871336 |
|
NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012 Ensembl chr 5:73,856,164...73,863,012
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|
G |
Gng7 |
G protein subunit gamma 7 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GNG7 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
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|
G |
Golt1a |
golgi transport 1A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GOLT1A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:44,760,356...44,773,123
Ensembl chr13:44,760,380...44,773,122
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|
G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of GOT1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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|
G |
Gpc3 |
glypican 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GPC3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798
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|
G |
Gpc4 |
glypican 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GPC4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
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|
G |
Gpnmb |
glycoprotein nmb |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GPNMB mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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|
G |
Gpr141 |
G protein-coupled receptor 141 |
increases expression |
ISO |
zoledronic acid results in increased expression of GPR141 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:45,117,818...45,180,053
Ensembl chr17:45,117,812...45,180,027
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|
G |
Gpr37l1 |
G protein-coupled receptor 37-like 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of GPR37L1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
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|
G |
Gprc5a |
G protein-coupled receptor, class C, group 5, member A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GPRC5A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
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|
G |
Grb14 |
growth factor receptor bound protein 14 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GRB14 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
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|
G |
Grip2 |
glutamate receptor interacting protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GRIP2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
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|
G |
Grk5 |
G protein-coupled receptor kinase 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of GRK5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
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|
G |
Grm8 |
glutamate metabotropic receptor 8 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GRM8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
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|
G |
Gtf2i |
general transcription factor II I |
increases expression |
ISO |
zoledronic acid results in increased expression of GTF2I mRNA |
CTD |
PMID:20977926 |
|
NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
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|
G |
Gtf2ird1 |
GTF2I repeat domain containing 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of GTF2IRD1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
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|
G |
Gtf3c4 |
general transcription factor IIIC subunit 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of GTF3C4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 3:12,154,803...12,172,795
Ensembl chr 3:12,154,805...12,172,725
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|
G |
Gtpbp2 |
GTP binding protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of GTPBP2 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
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|
G |
Gzmb |
granzyme B |
affects expression multiple interactions |
ISO |
zoledronic acid affects the expression of GZMB mRNA IL2 protein affects the reaction [zoledronic acid affects the expression of GZMB mRNA] |
CTD |
PMID:19446661 |
|
NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
|
|
G |
H1f2 |
H1.2 linker histone, cluster member |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H1-2 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
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|
G |
H2ac18 |
H2A clustered histone 18 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2AC18 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:183,808,398...183,808,992
|
|
G |
H2ac20 |
H2A clustered histone 20 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2AC20 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:183,779,879...183,780,357
|
|
G |
H2ax |
H2A.X variant histone |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2AX mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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|
G |
H2bc12 |
H2B clustered histone 12 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2BC12 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:42,485,699...42,486,162
|
|
G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HADHA mRNA |
CTD |
PMID:28871336 |
|
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
|
|
G |
Hapln3 |
hyaluronan and proteoglycan link protein 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of HAPLN3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HAVCR1 mRNA |
CTD |
PMID:28871336 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hdac9 |
histone deacetylase 9 |
increases expression |
ISO |
zoledronic acid results in increased expression of HDAC9 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdgf |
heparin binding growth factor |
increases expression |
ISO |
zoledronic acid results in increased expression of HDGF mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
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|
G |
Heg1 |
heart development protein with EGF-like domains 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HEG1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051
|
|
G |
Herc4 |
HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HERC4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657
|
|
G |
Hes1 |
hes family bHLH transcription factor 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HES1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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|
G |
Hes2 |
hes family bHLH transcription factor 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HES2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235
|
|
G |
Hgd |
homogentisate 1, 2-dioxygenase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HGD mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
|
|
G |
Hhla2 |
HHLA2 member of B7 family |
increases expression |
ISO |
zoledronic acid results in increased expression of HHLA2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr11:51,257,681...51,271,408
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
zoledronic acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein] |
CTD |
PMID:25818600 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
|
|
G |
Hint2 |
histidine triad nucleotide binding protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of HINT2 protein |
CTD |
PMID:28871336 |
|
NCBI chr 5:57,904,613...57,906,868
Ensembl chr 5:57,904,614...57,907,097
|
|
G |
Hist1h2al1 |
histone cluster 1 H2A family like 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2AC6 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:42,707,954...42,708,420
|
|
G |
Hist1h2bc |
histone cluster 1, H2bc |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2BC21 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
|
|
G |
Hist1h2bd |
histone cluster 1 H2B family member D |
increases expression |
ISO |
Zoledronic Acid results in increased expression of H2BC5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:42,792,887...42,793,268
|
|
G |
Hlf |
HLF transcription factor, PAR bZIP family member |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HLF mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
|
|
G |
Hmcn1 |
hemicentin 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HMCN1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
|
|
G |
Hmgb3 |
high mobility group box 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of HMGB3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292
|
|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HMGCS1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
|
|
G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HMMR mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
|
|
G |
Hmox1 |
heme oxygenase 1 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of HMOX1 mRNA Zoledronic Acid results in increased expression of HMOX1 mRNA |
CTD |
PMID:24714768 PMID:25596134 PMID:35587103 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hmox2 |
heme oxygenase 2 |
multiple interactions |
ISO |
[Tretinoin co-treated with zoledronic acid] results in increased expression of HMOX2 protein |
CTD |
PMID:20349282 |
|
NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
|
|
G |
Hp1bp3 |
heterochromatin protein 1, binding protein 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of HP1BP3 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000
|
|
G |
Hpcal4 |
hippocalcin-like 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HPCAL4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416
|
|
G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HPGD mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
decreases localization increases expression |
ISO |
zoledronic acid results in decreased localization of HRAS protein zoledronic acid results in increased expression of HRAS protein |
CTD |
PMID:11986784 PMID:28871336 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
|
|
G |
Hs3st1 |
heparan sulfate-glucosamine 3-sulfotransferase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HS3ST1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248
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|
G |
Hs3st3a1 |
heparan sulfate-glucosamine 3-sulfotransferase 3A1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HS3ST3A1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676
|
|
G |
Hs3st3b1 |
heparan sulfate-glucosamine 3-sulfotransferase 3B1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HS3ST3B1 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970
|
|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of HSD11B1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
|
|
G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HSD11B2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
|
|
G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of HSD17B2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
|
|
G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HSD17B4 mRNA |
CTD |
PMID:28871336 |
|
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
|
|
G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HSPA12A mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
|
|
G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of HSPA2 protein |
CTD |
PMID:28871336 |
|
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression decreases expression |
ISO |
zoledronic acid results in increased expression of HSPA5 mRNA Zoledronic Acid results in decreased expression of HSPA5 mRNA; Zoledronic Acid results in decreased expression of HSPA5 protein |
CTD |
PMID:25596134 PMID:35587103 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of HSPA6 protein |
CTD |
PMID:28871336 |
|
NCBI chr13:83,273,176...83,274,317
|
|
G |
Hspb8 |
heat shock protein family B (small) member 8 |
increases expression |
ISO |
zoledronic acid results in increased expression of HSPB8 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
|
|
G |
Htr4 |
5-hydroxytryptamine receptor 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of HTR4 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321
|
|
G |
Htra1 |
HtrA serine peptidase 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of HTRA1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
|
|
G |
Ibsp |
integrin-binding sialoprotein |
multiple interactions increases expression |
ISO |
[zoledronic acid results in decreased geranoylation of RHOA protein] which results in increased expression of IBSP mRNA; geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA]; zoledronic acid inhibits the reaction [RHOA protein results in decreased expression of IBSP mRNA]; zoledronic acid results in increased expression of and results in decreased degradation of IBSP mRNA zoledronic acid results in increased expression of IBSP protein |
CTD |
PMID:15324309 |
|
NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ICAM1 protein |
CTD |
PMID:19446661 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
|
|
G |
Icoslg |
inducible T-cell co-stimulator ligand |
increases expression |
ISO |
zoledronic acid results in increased expression of ICOSLG mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703
|
|
G |
Id1 |
inhibitor of DNA binding 1 |
multiple interactions |
ISO |
zoledronic acid promotes the reaction [Gossypol results in decreased expression of ID1 mRNA] |
CTD |
PMID:19825521 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
|
|
G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of ID3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
|
|
G |
Id4 |
inhibitor of DNA binding 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of ID4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
decreases expression increases expression |
ISO |
zoledronic acid results in decreased expression of IDH2 mRNA zoledronic acid results in increased expression of IDH2 protein |
CTD |
PMID:24714768 PMID:28871336 |
|
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
|
|
G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
increases expression |
ISO EXP |
zoledronic acid results in increased expression of IDI1 mRNA |
CTD |
PMID:18325729 PMID:24714768 |
|
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
|
|
G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of IDO1 mRNA; zoledronic acid results in increased expression of INDO mRNA |
CTD |
PMID:24714768 |
|
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
|
|
G |
Ier5 |
immediate early response 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of IER5 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
|
|
G |
Iffo2 |
intermediate filament family orphan 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of IFFO2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 5:151,830,900...151,876,948
Ensembl chr 5:151,830,701...151,925,345
|
|
G |
Ifi27 |
interferon, alpha-inducible protein 27 |
increases expression |
ISO |
zoledronic acid results in increased expression of IFI27 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
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|
G |
Ifng |
interferon gamma |
multiple interactions increases expression |
ISO |
zoledronic acid promotes the reaction [IL2 protein affects the expression of IFNG protein] zoledronic acid results in increased expression of IFNG protein |
CTD |
PMID:19400555 PMID:19818098 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Ifngr1 |
interferon gamma receptor 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of IFNGR1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
|
|
G |
Ift81 |
intraflagellar transport 81 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IFT81 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
|
|
G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of IGF1 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
|
|
G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of IGFBP5 mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
|
|
G |
Ikbke |
inhibitor of nuclear factor kappa B kinase subunit epsilon |
increases expression |
ISO |
zoledronic acid results in increased expression of IKBKE mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
|
|
G |
Ikzf5 |
IKAROS family zinc finger 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IKZF5 mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 1:186,169,108...186,188,847
Ensembl chr 1:186,170,788...186,188,834
|
|
G |
Il10 |
interleukin 10 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IL10 protein |
CTD |
PMID:19818098 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il10ra |
interleukin 10 receptor subunit alpha |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of IL10RA mRNA |
CTD |
PMID:16996129 |
|
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
|
|
G |
Il13ra2 |
interleukin 13 receptor subunit alpha 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of IL13RA2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381
|
|
G |
Il17rb |
interleukin 17 receptor B |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IL17RB mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
|
|
G |
Il18r1 |
interleukin 18 receptor 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of IL18R1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
|
|
G |
Il19 |
interleukin 19 |
increases expression increases secretion |
ISO |
zoledronic acid results in increased expression of IL19 mRNA zoledronic acid results in increased secretion of IL19 protein |
CTD |
PMID:24714768 |
|
NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
|
|
G |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
zoledronic acid results in increased expression of IL1B mRNA |
CTD |
PMID:24714768 PMID:28871336 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il1r1 |
interleukin 1 receptor type 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of IL1R1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
|
|
G |
Il1r2 |
interleukin 1 receptor type 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IL1R2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
|
|
G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
IL2 protein affects the reaction [zoledronic acid affects the expression of GZMB mRNA]; zoledronic acid promotes the reaction [IL2 protein affects the expression of IFNG protein] |
CTD |
PMID:19400555 PMID:19446661 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
|
|
G |
Il23a |
interleukin 23 subunit alpha |
increases expression |
ISO |
zoledronic acid results in increased expression of IL23A mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
|
|
G |
Il2rg |
interleukin 2 receptor subunit gamma |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of IL2RG mRNA |
CTD |
PMID:16996129 |
|
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
|
|
G |
Il36g |
interleukin 36, gamma |
increases expression |
ISO |
Zoledronic Acid results in increased expression of IL36G mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
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G |
Il4i1 |
interleukin 4 induced 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of IL4I1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
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G |
Il6 |
interleukin 6 |
decreases expression increases expression multiple interactions |
ISO |
Zoledronic Acid results in decreased expression of IL6 mRNA; Zoledronic Acid results in decreased expression of IL6 protein zoledronic acid results in increased expression of IL6 mRNA; zoledronic acid results in increased expression of IL6 protein SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of IL6 mRNA] |
CTD |
PMID:9351880 PMID:18601766 PMID:28871336 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il7 |
interleukin 7 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IL7 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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G |
Inhbe |
inhibin subunit beta E |
increases expression |
ISO |
zoledronic acid results in increased expression of INHBE mRNA |
CTD |
PMID:20977926 |
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NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of INSIG1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Iqcd |
IQ motif containing D |
increases expression |
ISO |
zoledronic acid results in increased expression of IQCD mRNA |
CTD |
PMID:24714768 |
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NCBI chr12:35,955,522...35,972,420
Ensembl chr12:35,934,716...35,972,523
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G |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of IRAK2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of IREB2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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G |
Irf2 |
interferon regulatory factor 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of IRF2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
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G |
Irf2bp1 |
interferon regulatory factor 2 binding protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IRF2BP1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530
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G |
Irf2bpl |
interferon regulatory factor 2 binding protein-like |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IRF2BPL mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
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G |
Irf8 |
interferon regulatory factor 8 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IRF8 mRNA |
CTD |
PMID:24714768 |
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NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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G |
Irx3 |
iroquois homeobox 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IRX3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317
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G |
Ism1 |
isthmin 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ISM1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:127,023,296...127,102,228
Ensembl chr 3:127,021,865...127,101,894
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G |
Ism2 |
isthmin 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ISM2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514
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G |
Itfg2 |
integrin alpha FG-GAP repeat containing 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ITFG2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
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G |
Itga1 |
integrin subunit alpha 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of ITGA1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
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G |
Itgb2 |
integrin subunit beta 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of ITGB2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Itgb5 |
integrin subunit beta 5 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ITGB5 mRNA |
CTD |
PMID:24714768 |
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NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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G |
Itih3 |
inter-alpha trypsin inhibitor, heavy chain 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of ITIH3 protein |
CTD |
PMID:28871336 |
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NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
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G |
Itprid2 |
ITPR interacting domain containing 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of ITPRID2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
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G |
Ivns1abp |
influenza virus NS1A binding protein |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IVNS1ABP mRNA |
CTD |
PMID:24714768 |
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NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
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G |
Iyd |
iodotyrosine deiodinase |
decreases expression |
ISO |
zoledronic acid results in decreased expression of IYD mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Izumo4 |
IZUMO family member 4 |
increases expression |
ISO |
zoledronic acid results in increased expression of IZUMO4 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:9,007,276...9,010,428
Ensembl chr 7:9,007,280...9,010,032
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G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of JAK1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of JAK2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jak3 |
Janus kinase 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of JAK3 mRNA |
CTD |
PMID:20977926 |
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NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
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G |
Josd1 |
Josephin domain containing 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of JOSD1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 7:111,230,318...111,244,241
Ensembl chr 7:111,230,318...111,244,652
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G |
Kat2b |
lysine acetyltransferase 2B |
multiple interactions |
ISO |
[zoledronic acid co-treated with fluvastatin] results in increased expression of KAT2B mRNA |
CTD |
PMID:16996129 |
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NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
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G |
Kbtbd2 |
kelch repeat and BTB domain containing 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of KBTBD2 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211
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G |
Kcnh1 |
potassium voltage-gated channel subfamily H member 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KCNH1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
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G |
Kcnh3 |
potassium voltage-gated channel subfamily H member 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KCNH3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:130,365,593...130,383,859
Ensembl chr 7:130,366,011...130,383,855
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G |
Kcnip3 |
potassium voltage-gated channel interacting protein 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of KCNIP3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
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G |
Kcnip4 |
potassium voltage-gated channel interacting protein 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KCNIP4 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:61,380,699...62,531,399
Ensembl chr14:61,381,076...62,530,144
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G |
Kcnj1 |
potassium inwardly-rectifying channel, subfamily J, member 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KCNJ1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
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G |
Kcns3 |
potassium voltage-gated channel, modifier subfamily S, member 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of KCNS3 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125
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G |
Kctd5 |
potassium channel tetramerization domain containing 5 |
increases expression |
ISO |
zoledronic acid results in increased expression of KCTD5 mRNA |
CTD |
PMID:20977926 |
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NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209
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G |
Kdm3a |
lysine demethylase 3A |
increases expression |
ISO |
zoledronic acid results in increased expression of KDM3A mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
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G |
Kiaa0930 |
KIAA0930 homolog |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KIAA0930 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:116,067,974...116,107,678
Ensembl chr 7:116,071,447...116,107,727
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G |
Kif13a |
kinesin family member 13A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KIF13A protein |
CTD |
PMID:28871336 |
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NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615
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G |
Kif20a |
kinesin family member 20A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KIF20A mRNA |
CTD |
PMID:20977926 PMID:24714768 |
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NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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G |
Kif4a |
kinesin family member 4A |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KIF4A mRNA |
CTD |
PMID:24714768 |
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NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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G |
Kifc1 |
kinesin family member C1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KIFC1 mRNA |
CTD |
PMID:24714768 |
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NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
zoledronic acid results in increased expression of KIT mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KITLG mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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G |
Klf11 |
KLF transcription factor 11 |
increases expression |
ISO |
zoledronic acid results in increased expression of KLF11 mRNA |
CTD |
PMID:20977926 PMID:24714768 |
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NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
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G |
Klf7 |
KLF transcription factor 7 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of KLF7 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
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G |
Klhl13 |
kelch-like family member 13 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KLHL13 mRNA |
CTD |
PMID:24714768 |
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NCBI chr X:113,942,309...114,107,299
Ensembl chr X:113,942,309...114,107,321
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G |
Klk10 |
kallikrein related-peptidase 10 |
increases expression |
ISO |
zoledronic acid results in increased expression of KLK10 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376
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G |
Klk6 |
kallikrein related-peptidase 6 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KLK6 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
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G |
Klrg2 |
killer cell lectin like receptor G2 |
increases expression |
ISO |
zoledronic acid results in increased expression of KLRG2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147
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G |
Kras |
KRAS proto-oncogene, GTPase |
increases expression |
ISO |
zoledronic acid results in increased expression of KRAS protein |
CTD |
PMID:28871336 |
|
NCBI chr 4:178,185,418...178,218,484
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G |
Krcc1 |
lysine-rich coiled-coil 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of KRCC1 mRNA |
CTD |
PMID:20977926 |
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NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156
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G |
Krt15 |
keratin 15 |
increases expression |
ISO |
zoledronic acid results in increased expression of KRT15 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799
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G |
Krt8 |
keratin 8 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KRT8 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Krt80 |
keratin 80 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KRT80 mRNA |
CTD |
PMID:24714768 |
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NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508
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G |
Krt81 |
keratin 81 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of KRT81 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
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G |
Kynu |
kynureninase |
increases expression |
ISO |
zoledronic acid results in increased expression of KYNU mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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G |
L3mbtl3 |
L3MBTL histone methyl-lysine binding protein 3 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of L3MBTL3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263
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G |
Lama1 |
laminin subunit alpha 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LAMA1 mRNA |
CTD |
PMID:24714768 PMID:25596134 |
|
NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
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G |
Lama3 |
laminin subunit alpha 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of LAMA3 mRNA |
CTD |
PMID:20977926 PMID:24714768 PMID:25596134 |
|
NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
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G |
Lama4 |
laminin subunit alpha 4 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LAMA4 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lama5 |
laminin subunit alpha 5 |
multiple interactions |
ISO |
[zoledronic acid co-treated with Gossypol] results in decreased expression of LAMA5 mRNA |
CTD |
PMID:19825521 |
|
NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
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G |
Lamb1 |
laminin subunit beta 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LAMB1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamb3 |
laminin subunit beta 3 |
increases expression |
ISO |
zoledronic acid results in increased expression of LAMB3 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
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G |
Lamc2 |
laminin subunit gamma 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of LAMC2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LAMP1 protein |
CTD |
PMID:28871336 |
|
NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
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G |
Lbh |
LBH regulator of WNT signaling pathway |
increases expression |
ISO |
zoledronic acid results in increased expression of LBH mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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G |
Lcn2 |
lipocalin 2 |
increases expression increases secretion |
ISO |
zoledronic acid results in increased expression of LCN2 mRNA zoledronic acid results in increased secretion of LCN2 protein |
CTD |
PMID:24714768 |
|
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of LCP1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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G |
Ldaf1 |
lipid droplet assembly factor 1 |
increases expression |
ISO |
Zoledronic Acid results in increased expression of LDAF1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:174,484,438...174,503,037
Ensembl chr 1:174,484,447...174,503,036
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|
G |
Ldb2 |
LIM domain binding 2 |
increases expression |
ISO |
zoledronic acid results in increased expression of LDB2 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
zoledronic acid results in increased expression of LDLR mRNA |
CTD |
PMID:20977926 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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|
G |
Ldoc1 |
LDOC1, regulator of NFKB signaling |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LDOC1 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr X:139,965,509...140,074,355
Ensembl chr X:139,965,509...140,074,355
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|
G |
Leg1 |
liver enriched gene 1 |
increases expression |
ISO |
zoledronic acid results in increased expression of C6ORF58 mRNA |
CTD |
PMID:24714768 |
|
NCBI chr 1:28,799,902...28,816,230
Ensembl chr 1:28,799,902...28,815,993
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G |
Lgi2 |
leucine-rich repeat LGI family, member 2 |
decreases expression |
ISO |
zoledronic acid results in decreased expression of LGI2 mRNA |
CTD |
PMID:24714768 |
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NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407
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