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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zoledronic acid
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Accession:CHEBI:46557 term browser browse the term
Definition:An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.
Synonyms:exact_synonym: [1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
 related_synonym: (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid;   (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid;   Formula=C5H10N2O7P2;   InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);   InChIKey=XRASPMIURGNCCH-UHFFFAOYSA-N;   Reclast;   SMILES=OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O;   ZOL
 xref: Beilstein:9205049;   CAS:118072-93-8;   Chemspider:61986;   DrugBank:DB00399;   Drug_Central:2868;   Gmelin:2609374;   KEGG:D08689
 xref_mesh: MESH:C088658
 xref: PDBeChem:ZOL;   PMCID:PMC8090009;   PMID:12183663;   PMID:15161327;   PMID:15324309;   PMID:16414486;   PMID:17691952;   PMID:18982915;   PMID:19751105;   PMID:33908127;   PMID:33984339;   PMID:34081204;   PMID:34157824;   PMID:34324430;   PMID:34341833;   PMID:34393156;   PMID:34413050;   PMID:34435997;   PMID:34447747;   PMID:34475752;   PMID:34560734;   PMID:34585443;   Patent:US4939130;   Wikipedia:Zoledronic_Acid



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zoledronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase increases expression ISO zoledronic acid results in increased expression of A4GALT mRNA CTD PMID:24714768 NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071
JBrowse link
G Aadat aminoadipate aminotransferase decreases expression ISO zoledronic acid results in decreased expression of AADAT mRNA CTD PMID:24714768 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Zoledronic Acid results in decreased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO zoledronic acid results in increased expression of ABCA12 mRNA CTD PMID:24714768 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 increases expression ISO zoledronic acid results in increased expression of ABCA4 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression ISO zoledronic acid results in decreased expression of ABCB6 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression ISO zoledronic acid results in decreased expression of ABCC5 mRNA CTD PMID:24714768 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO zoledronic acid results in increased expression of ABCG2 mRNA CTD PMID:18225567 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abhd17c abhydrolase domain containing 17C, depalmitoylase decreases expression ISO zoledronic acid results in decreased expression of ABHD17C mRNA CTD PMID:24714768 NCBI chr 1:138,084,632...138,125,595
Ensembl chr 1:138,084,634...138,125,595
JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO zoledronic acid results in decreased expression of ABI3BP mRNA CTD PMID:24714768 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
JBrowse link
G Abtb3 ankyrin repeat and BTB domain containing 3 decreases expression ISO Zoledronic Acid results in decreased expression of ABTB3 mRNA CTD PMID:24714768 NCBI chr 7:18,035,151...18,310,718
Ensembl chr 7:18,036,083...18,310,834
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO zoledronic acid results in decreased expression of ACAA1 mRNA CTD PMID:28871336 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO zoledronic acid results in decreased expression of ACADL mRNA CTD PMID:28871336 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO zoledronic acid results in decreased expression of ACADM mRNA CTD PMID:28871336 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression ISO zoledronic acid results in increased expression of ACAT2 mRNA CTD PMID:24714768 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acbd4 acyl-CoA binding domain containing 4 decreases expression ISO zoledronic acid results in decreased expression of ACBD4 mRNA CTD PMID:20977926 NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO zoledronic acid results in decreased expression of ACMSD mRNA CTD PMID:24714768 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of ACOX1 mRNA; zoledronic acid results in decreased expression of ACOX1 protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]
CTD PMID:28871336 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions
decreases expression
ISO Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] CTD PMID:28871336 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acp3 acid phosphatase 3 decreases expression ISO Zoledronic Acid results in decreased expression of ACP3 mRNA CTD PMID:24714768 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Zoledronic Acid results in decreased expression of ACSL1 mRNA; Zoledronic Acid results in decreased expression of ACSL1 protein CTD PMID:25596134 PMID:28871336 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO zoledronic acid results in decreased expression of ACSL3 protein CTD PMID:28871336 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO zoledronic acid results in increased expression of ACSL5 mRNA CTD PMID:24714768 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO zoledronic acid results in decreased expression of ACSM3 mRNA CTD PMID:24714768 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO zoledronic acid results in increased expression of ACSS2 mRNA CTD PMID:24714768 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO zoledronic acid results in increased expression of ACTA2 protein
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]
CTD PMID:28871336 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO zoledronic acid results in increased expression of ACTBL2 mRNA CTD PMID:24714768 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO zoledronic acid results in decreased expression of ACTG2 mRNA CTD PMID:24714768 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO zoledronic acid results in decreased expression of ACTN1 protein CTD PMID:28871336 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Actn4 actinin alpha 4 decreases expression ISO zoledronic acid results in decreased expression of ACTN4 protein CTD PMID:28871336 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions
decreases activity
increases expression
ISO ADAM17 protein promotes the reaction [zoledronic acid results in decreased expression of TNFSF11 protein]
zoledronic acid results in decreased activity of ADAM17 protein
zoledronic acid results in increased expression of ADAM17 protein
CTD PMID:14753746 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO zoledronic acid results in decreased expression of ADAM19 mRNA CTD PMID:24714768 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 increases expression ISO zoledronic acid results in increased expression of ADAM28 mRNA CTD PMID:24714768 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO zoledronic acid results in increased expression of ADAMTS1 mRNA CTD PMID:24714768 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression ISO zoledronic acid results in increased expression of ADAMTS9 mRNA CTD PMID:24714768 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
JBrowse link
G Adamtsl3 ADAMTS-like 3 decreases expression ISO zoledronic acid results in decreased expression of ADAMTSL3 mRNA CTD PMID:24714768 NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 increases expression ISO zoledronic acid results in increased expression of ADGRF1 mRNA CTD PMID:24714768 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO zoledronic acid results in decreased expression of ADGRG1 mRNA CTD PMID:24714768 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 decreases expression ISO zoledronic acid results in decreased expression of ADGRL1 mRNA CTD PMID:20977926 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases expression ISO zoledronic acid results in increased expression of ADGRV1 mRNA CTD PMID:24714768 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) decreases expression ISO Zoledronic Acid results in decreased expression of ADH6 mRNA CTD PMID:24714768 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Adm2 adrenomedullin 2 decreases expression ISO zoledronic acid results in decreased expression of ADM2 mRNA CTD PMID:24714768 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
JBrowse link
G Adsl adenylosuccinate lyase decreases expression ISO zoledronic acid results in decreased expression of ADSL mRNA CTD PMID:20977926 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
G Afp alpha-fetoprotein increases expression ISO zoledronic acid results in increased expression of AFP protein CTD PMID:28871336 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 increases expression ISO zoledronic acid results in increased expression of AGPAT5 mRNA CTD PMID:24714768 NCBI chr16:70,939,480...70,985,745
Ensembl chr16:70,943,135...70,985,560
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member decreases expression ISO zoledronic acid results in decreased expression of AGR2 mRNA CTD PMID:24714768 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Agrn agrin increases expression ISO zoledronic acid results in increased expression of AGRN protein CTD PMID:28871336 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 decreases expression ISO zoledronic acid results in decreased expression of AHNAK2 mRNA CTD PMID:24714768 NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO zoledronic acid affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO zoledronic acid results in increased expression of AHSG protein CTD PMID:28871336 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO zoledronic acid results in decreased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Ak5 adenylate kinase 5 decreases expression ISO zoledronic acid results in decreased expression of AK5 mRNA CTD PMID:24714768 NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO zoledronic acid results in decreased expression of AKAP7 mRNA CTD PMID:24714768 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Akip1 A-kinase interacting protein 1 increases expression ISO zoledronic acid results in increased expression of AKIP1 mRNA CTD PMID:24714768 NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648
JBrowse link
G Akirin2 akirin 2 decreases expression ISO zoledronic acid results in decreased expression of AKIRIN2 mRNA CTD PMID:20977926 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO zoledronic acid results in increased expression of AKR1A1 mRNA CTD PMID:24714768 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression ISO zoledronic acid results in increased expression of AKR1B1 mRNA CTD PMID:24714768 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO zoledronic acid results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:19530242 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression ISO zoledronic acid results in increased expression of AKT1S1 mRNA CTD PMID:20977926 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Alb albumin increases expression ISO zoledronic acid results in increased expression of ALB protein CTD PMID:28871336 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO zoledronic acid results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO zoledronic acid results in increased expression of ALDH1A3 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO zoledronic acid results in decreased expression of ALDH3A2 mRNA CTD PMID:24714768 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO zoledronic acid results in increased expression of ALDH8A1 mRNA CTD PMID:24714768 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO zoledronic acid results in increased expression of ALOX5 mRNA CTD PMID:24714768 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO zoledronic acid results in increased expression of ALOX5AP mRNA CTD PMID:20977926 PMID:24714768 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO zoledronic acid results in increased expression of ALPK2 mRNA CTD PMID:24714768 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases activity
multiple interactions
ISO zoledronic acid results in decreased activity of ALPL protein
TNFRSF11B protein affects the reaction [zoledronic acid results in decreased activity of ALPL protein]
CTD PMID:18496637 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO zoledronic acid results in increased expression of ALS2CL mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
JBrowse link
G Ank2 ankyrin 2 decreases expression ISO zoledronic acid results in decreased expression of ANK2 mRNA CTD PMID:24714768 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ankef1 ankyrin repeat and EF-hand domain containing 1 increases expression ISO zoledronic acid results in increased expression of ANKEF1 mRNA CTD PMID:20977926 NCBI chr 3:123,847,832...123,883,060
Ensembl chr 3:123,847,817...123,883,059
JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression ISO zoledronic acid results in increased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730
JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO zoledronic acid results in increased expression of ANKRD10 mRNA CTD PMID:20977926 NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO zoledronic acid results in increased expression of ANKRD22 mRNA CTD PMID:24714768 NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO zoledronic acid results in decreased expression of ANLN mRNA CTD PMID:24714768 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anpep alanyl aminopeptidase, membrane increases expression ISO zoledronic acid results in increased expression of ANPEP mRNA CTD PMID:24714768 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Anxa2 annexin A2 decreases expression ISO zoledronic acid results in decreased expression of ANXA2 protein CTD PMID:28871336 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 increases expression ISO zoledronic acid results in increased expression of AP1S2 mRNA CTD PMID:24714768 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 increases expression ISO zoledronic acid results in increased expression of AP1S3 mRNA CTD PMID:20977926 NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G Ap4b1 adaptor related protein complex 4 subunit beta 1 increases expression ISO zoledronic acid results in increased expression of AP4B1 mRNA CTD PMID:24714768 NCBI chr 2:191,318,485...191,330,531
Ensembl chr 2:191,318,482...191,330,531
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO zoledronic acid results in increased expression of APAF1 mRNA CTD PMID:28871336 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apba3 amyloid beta precursor protein binding family A member 3 decreases expression ISO zoledronic acid results in decreased expression of APBA3 mRNA CTD PMID:20977926 NCBI chr 7:8,446,212...8,451,310
Ensembl chr 7:8,446,216...8,451,241
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit increases expression ISO zoledronic acid results in increased expression of APH1A mRNA CTD PMID:20977926 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955
JBrowse link
G Api5 apoptosis inhibitor 5 increases expression ISO zoledronic acid results in increased expression of API5 mRNA CTD PMID:20977926 NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264
JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 decreases expression ISO zoledronic acid results in decreased expression of ARAP1 mRNA CTD PMID:20977926 NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP18 mRNA CTD PMID:20977926 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
JBrowse link
G Arhgap19 Rho GTPase activating protein 19 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP19 mRNA CTD PMID:20977926 NCBI chr 1:240,571,554...240,617,361
Ensembl chr 1:240,580,871...240,617,287
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression ISO zoledronic acid results in increased expression of ARHGAP22 mRNA CTD PMID:24714768 NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression ISO zoledronic acid results in decreased expression of ARHGAP24 mRNA CTD PMID:24714768 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 increases expression ISO zoledronic acid results in increased expression of ARHGAP26 mRNA CTD PMID:24714768 NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGAP29 mRNA CTD PMID:16996129 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO zoledronic acid results in decreased expression of ARHGDIA protein CTD PMID:28871336 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF12 mRNA CTD PMID:16996129 NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ARHGEF3 mRNA CTD PMID:16996129 NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 decreases expression ISO zoledronic acid results in decreased expression of ARHGEF4 mRNA CTD PMID:24714768 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075
JBrowse link
G Arid2 AT-rich interaction domain 2 decreases expression ISO zoledronic acid results in decreased expression of ARID2 mRNA CTD PMID:20977926 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
JBrowse link
G Arl14 ARF like GTPase 14 decreases expression ISO zoledronic acid results in decreased expression of ARL14 mRNA CTD PMID:24714768 NCBI chr 2:153,468,863...153,470,102
Ensembl chr 2:153,468,977...153,469,555
JBrowse link
G Arl4c ARF like GTPase 4C decreases expression ISO zoledronic acid results in decreased expression of ARL4C mRNA CTD PMID:24714768 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Arl5b ARF like GTPase 5B increases expression ISO zoledronic acid results in increased expression of ARL5B mRNA CTD PMID:20977926 NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression ISO zoledronic acid results in decreased expression of ARNT2 mRNA CTD PMID:24714768 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO zoledronic acid results in increased expression of ARRDC3 mRNA CTD PMID:24714768 NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression ISO zoledronic acid results in increased expression of ARRDC4 mRNA CTD PMID:24714768 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions
decreases expression
ISO
EXP
zoledronic acid inhibits the reaction [Freund's Adjuvant results in increased expression of ASIC1 mRNA]
zoledronic acid results in decreased expression of ASIC1 mRNA
CTD PMID:16769263 PMID:17323179 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO zoledronic acid results in decreased expression of ASNS mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asphd2 aspartate beta-hydroxylase domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of ASPHD2 mRNA CTD PMID:24714768 NCBI chr12:44,248,132...44,258,653
Ensembl chr12:44,248,145...44,257,772
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO zoledronic acid results in decreased expression of ASPM mRNA CTD PMID:24714768 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO zoledronic acid results in decreased expression of ATF4 mRNA CTD PMID:24714768 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO zoledronic acid results in increased expression of ATF5 mRNA CTD PMID:24714768 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atg2a autophagy related 2A increases expression ISO zoledronic acid results in increased expression of ATG2A protein CTD PMID:28871336 NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO zoledronic acid results in increased expression of ATOH8 mRNA CTD PMID:24714768 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Atosa atos homolog A increases expression ISO Zoledronic Acid results in increased expression of ATOSA mRNA CTD PMID:25596134 NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549
JBrowse link
G Atp10b ATPase phospholipid transporting 10B increases expression ISO zoledronic acid results in increased expression of ATP10B mRNA CTD PMID:24714768 NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression ISO zoledronic acid results in decreased expression of ATP1A1 mRNA CTD PMID:24714768 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 decreases expression ISO zoledronic acid results in decreased expression of ATP6V0A4 mRNA CTD PMID:24714768 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO zoledronic acid results in decreased expression of ATP6V1B1 mRNA CTD PMID:24714768 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Atp7b ATPase copper transporting beta decreases expression ISO zoledronic acid results in decreased expression of ATP7B mRNA CTD PMID:24714768 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO zoledronic acid results in decreased expression of ATRX mRNA CTD PMID:20977926 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Atxn1 ataxin 1 increases expression ISO zoledronic acid results in increased expression of ATXN1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G Aurkb aurora kinase B decreases expression ISO zoledronic acid results in decreased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Avpi1 arginine vasopressin-induced 1 decreases expression ISO zoledronic acid results in decreased expression of AVPI1 mRNA CTD PMID:24714768 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO zoledronic acid results in decreased expression of AXL mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 decreases expression ISO zoledronic acid results in decreased expression of B3GALT5 mRNA CTD PMID:24714768 NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression ISO zoledronic acid results in increased expression of BAAT mRNA CTD PMID:24714768 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
ISO [Tretinoin co-treated with zoledronic acid] results in increased expression of BAD protein
zoledronic acid results in increased expression of BAD mRNA
CTD PMID:19036117 PMID:20349282 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO zoledronic acid results in increased expression of BAG1 mRNA CTD PMID:19036117 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO zoledronic acid results in increased expression of BAG3 mRNA CTD PMID:19036117 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO zoledronic acid results in increased expression of BASP1 mRNA CTD PMID:24714768 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
increases expression
ISO zoledronic acid results in decreased expression of BAX mRNA
[Tretinoin co-treated with zoledronic acid] results in increased expression of BAX protein
[zoledronic acid co-treated with Doxorubicin] results in increased expression of BAX protein
zoledronic acid results in increased expression of BAX mRNA
Zoledronic Acid results in increased expression of BAX mRNA
CTD PMID:19036117 PMID:19789217 PMID:20349282 PMID:28871336 PMID:35587103 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbln bublin coiled coil protein increases expression ISO Zoledronic Acid results in increased expression of BBLN mRNA CTD PMID:24714768 NCBI chr 3:15,674,577...15,677,322
Ensembl chr 3:15,674,580...15,677,374
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO zoledronic acid results in decreased expression of BBOX1 mRNA CTD PMID:24714768 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bbx BBX high mobility group box domain containing decreases expression ISO zoledronic acid results in decreased expression of BBX mRNA CTD PMID:20977926 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BCAP29 mRNA CTD PMID:16996129 NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression ISO Zoledronic Acid results in decreased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bche butyrylcholinesterase decreases expression ISO zoledronic acid results in decreased expression of BCHE mRNA CTD PMID:24714768 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
decreases expression
affects expression
increases expression
ISO BCL2 protein results in decreased susceptibility to zoledronic acid
[Tretinoin co-treated with zoledronic acid] results in decreased expression of BCL2 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of BCL2 protein
zoledronic acid results in decreased expression of BCL2 mRNA
zoledronic acid affects the expression of BCL2 mRNA
Zoledronic Acid results in increased expression of BCL2 mRNA
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of BCL2 protein
CTD PMID:11986784 PMID:18225567 PMID:19036117 PMID:19103299 PMID:19789217 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO zoledronic acid results in decreased expression of BCL2A1 mRNA CTD PMID:19036117 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO zoledronic acid results in increased expression of BCL2L1 mRNA CTD PMID:19036117 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 affects expression ISO zoledronic acid affects the expression of BCL2L10 mRNA CTD PMID:19036117 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNA CTD PMID:16996129 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l15 Bcl2-like 15 increases expression ISO zoledronic acid results in increased expression of BCL2L15 mRNA CTD PMID:24714768 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO zoledronic acid results in increased expression of BCL2L2 mRNA CTD PMID:19036117 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Becn1 beclin 1 decreases expression ISO zoledronic acid results in decreased expression of BECN1 protein CTD PMID:28871336 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO zoledronic acid results in decreased expression of BEND5 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
JBrowse link
G Bfsp1 beaded filament structural protein 1 decreases expression ISO zoledronic acid results in decreased expression of BFSP1 mRNA CTD PMID:24714768 NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO zoledronic acid results in increased expression of BGLAP mRNA CTD PMID:14751568 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BHLHE40 mRNA CTD PMID:16996129 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bicdl1 BICD family like cargo adaptor 1 increases expression ISO zoledronic acid results in increased expression of BICDL1 mRNA CTD PMID:20977926 NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO zoledronic acid results in increased expression of BID mRNA CTD PMID:19036117 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
decreases expression
ISO [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC2 mRNA
zoledronic acid results in decreased expression of BIRC2 mRNA
CTD PMID:19036117 PMID:20349282 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO zoledronic acid results in increased expression of BIRC3 mRNA CTD PMID:24714768 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 mRNA; [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC5 protein
zoledronic acid results in decreased expression of BIRC5 mRNA; zoledronic acid results in decreased expression of BIRC5 protein
CTD PMID:19036117 PMID:20349282 PMID:24714768 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 decreases expression ISO zoledronic acid results in decreased expression of BIRC6 mRNA CTD PMID:19036117 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Bivm basic, immunoglobulin-like variable motif containing decreases expression ISO zoledronic acid results in decreased expression of BIVM mRNA CTD PMID:24714768 NCBI chr 9:46,268,758...46,305,038
Ensembl chr 9:46,269,252...46,305,024
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex 1 subunit 5 increases expression ISO zoledronic acid results in increased expression of BLOC1S5 mRNA CTD PMID:20977926 NCBI chr17:26,171,965...26,197,276
Ensembl chr17:26,172,018...26,197,251
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO Zoledronic Acid results in increased expression of BMAL1 mRNA CTD PMID:20977926 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO zoledronic acid results in increased expression of BMF mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp1 bone morphogenetic protein 1 increases expression ISO zoledronic acid results in increased expression of BMP1 mRNA CTD PMID:20977926 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO zoledronic acid results in increased expression of BMP2 mRNA CTD PMID:14751568 PMID:24714768 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression ISO zoledronic acid results in increased expression of BMPR1A mRNA CTD PMID:24714768 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression ISO zoledronic acid results in increased expression of BMPR2 mRNA CTD PMID:20977926 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of BNIP3 mRNA
zoledronic acid results in increased expression of BNIP3 mRNA
CTD PMID:19036117 PMID:25596134 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip5 BCL2 interacting protein 5 increases expression ISO Zoledronic Acid results in increased expression of BNIP5 mRNA CTD PMID:24714768 NCBI chr20:6,957,736...6,975,062
Ensembl chr20:6,956,201...6,975,091
JBrowse link
G Bola2 bolA family member 2 increases expression ISO zoledronic acid results in increased expression of BOLA2 mRNA CTD PMID:24714768 NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO zoledronic acid results in increased expression of BPGM mRNA CTD PMID:24714768 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO zoledronic acid results in increased expression of BRCA2 mRNA CTD PMID:20977926 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brip1 BRCA1 interacting DNA helicase 1 increases expression ISO zoledronic acid results in increased expression of BRIP1 mRNA CTD PMID:20977926 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of BTG2 mRNA
zoledronic acid results in increased expression of BTG2 mRNA
CTD PMID:20977926 PMID:25596134 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of BUB1 mRNA CTD PMID:16996129 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C13h1orf53 similar to human chromosome 1 open reading frame 53 decreases expression ISO zoledronic acid results in decreased expression of C1ORF53 mRNA CTD PMID:24714768 NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120
JBrowse link
G C14h4orf19 similar to human chromosome 4 open reading frame 19 increases expression ISO zoledronic acid results in increased expression of C4ORF19 mRNA CTD PMID:24714768 NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041
JBrowse link
G C14h7orf57 similar to human chromosome 7 open reading frame 57 decreases expression ISO zoledronic acid results in decreased expression of C7ORF57 mRNA CTD PMID:24714768 NCBI chr14:83,748,478...83,768,293
Ensembl chr14:83,748,478...83,767,435
JBrowse link
G C1ql4 complement C1q like 4 decreases expression ISO zoledronic acid results in decreased expression of C1QL4 mRNA CTD PMID:24714768 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678
JBrowse link
G C1qtnf1 C1q and TNF related 1 increases expression ISO zoledronic acid results in increased expression of C1QTNF1 mRNA CTD PMID:24714768 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G C1qtnf6 C1q and TNF related 6 decreases expression ISO zoledronic acid results in decreased expression of C1QTNF6 mRNA CTD PMID:24714768 NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
JBrowse link
G C1r complement C1r increases expression ISO zoledronic acid results in increased expression of C1R mRNA CTD PMID:24714768 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
JBrowse link
G C1s complement C1s increases expression ISO zoledronic acid results in increased expression of C1S mRNA CTD PMID:24714768 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C20h6orf89 similar to human chromosome 6 open reading frame 89 increases expression ISO zoledronic acid results in increased expression of C6ORF89 mRNA CTD PMID:20977926 NCBI chr20:7,322,483...7,362,054
Ensembl chr20:7,322,442...7,357,612
JBrowse link
G C2cd4a C2 calcium-dependent domain containing 4A increases expression ISO zoledronic acid results in increased expression of C2CD4A mRNA CTD PMID:24714768 NCBI chr 8:68,467,017...68,469,781
Ensembl chr 8:68,466,664...68,470,031
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO zoledronic acid results in increased expression of NLF2 mRNA CTD PMID:24714768 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C3 complement C3 increases expression ISO zoledronic acid results in increased expression of C3 mRNA CTD PMID:24714768 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 increases expression ISO zoledronic acid results in increased expression of C15ORF48 mRNA CTD PMID:24714768 NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006
Ensembl chr 3:109,719,897...109,724,006
JBrowse link
G C3h15orf62 similar to human chromosome 15 open reading frame 62 increases expression ISO zoledronic acid results in increased expression of C15ORF62 mRNA CTD PMID:24714768 NCBI chr 3:106,164,179...106,167,404
Ensembl chr 3:106,157,382...106,167,831
JBrowse link
G C4bpa complement component 4 binding protein, alpha increases expression ISO zoledronic acid results in increased expression of C4BPA mRNA CTD PMID:24714768 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C6h14orf132 similar to human chromosome 14 open reading frame 132 decreases expression ISO zoledronic acid results in decreased expression of C14ORF132 mRNA CTD PMID:24714768 NCBI chr 6:124,365,466...124,398,449 JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 increases expression ISO zoledronic acid results in increased expression of CACNA2D3 mRNA CTD PMID:24714768 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
JBrowse link
G Cactin cactin, spliceosome C complex subunit decreases expression ISO zoledronic acid results in decreased expression of CACTIN protein CTD PMID:28871336 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO zoledronic acid results in decreased expression of CALM1 protein CTD PMID:28871336 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calml4 calmodulin-like 4 decreases expression ISO zoledronic acid results in decreased expression of CALML4 mRNA CTD PMID:20977926 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO zoledronic acid results in increased expression of CAMK1D mRNA CTD PMID:24714768 NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression ISO zoledronic acid results in decreased expression of CAMK2D mRNA CTD PMID:24714768 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 decreases expression ISO zoledronic acid results in decreased expression of CAMK2N1 mRNA CTD PMID:24714768 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO zoledronic acid results in decreased expression of CAMK4 protein CTD PMID:28871336 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 decreases expression ISO zoledronic acid results in decreased expression of CAMSAP1 protein CTD PMID:28871336 NCBI chr 3:8,746,176...8,806,067
Ensembl chr 3:8,746,176...8,806,072
JBrowse link
G Cant1 calcium activated nucleotidase 1 increases expression ISO zoledronic acid results in increased expression of CANT1 mRNA CTD PMID:20977926 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression ISO zoledronic acid results in decreased expression of CAP2 mRNA CTD PMID:24714768 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
JBrowse link
G Capn13 calpain 13 increases expression ISO zoledronic acid results in increased expression of CAPN13 mRNA CTD PMID:24714768 NCBI chr 6:22,071,845...22,166,864
Ensembl chr 6:22,071,845...22,166,850
JBrowse link
G Capn6 calpain 6 decreases expression ISO zoledronic acid results in decreased expression of CAPN6 mRNA CTD PMID:24714768 NCBI chr  X:107,380,774...107,405,489
Ensembl chr  X:107,380,774...107,405,489
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression ISO zoledronic acid results in increased expression of CAPRIN1 mRNA CTD PMID:20977926 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Card10 caspase recruitment domain family, member 10 decreases expression ISO zoledronic acid results in decreased expression of CARD10 mRNA CTD PMID:24714768 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 increases expression ISO Zoledronic Acid results in increased expression of CARS1 mRNA CTD PMID:20977926 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Casp1 caspase 1 affects expression
multiple interactions
increases expression
ISO zoledronic acid affects the expression of CASP1 mRNA
[zoledronic acid co-treated with fluvastatin] results in increased expression of CASP1 mRNA
zoledronic acid results in increased expression of CASP1 mRNA
CTD PMID:16996129 PMID:19036117 PMID:24714768 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp14 caspase 14 decreases expression ISO zoledronic acid results in decreased expression of CASP14 mRNA CTD PMID:19036117 NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
JBrowse link
G Casp2 caspase 2 affects expression ISO zoledronic acid affects the expression of CASP2 mRNA CTD PMID:19036117 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases activity
increases cleavage
increases expression
ISO [Tretinoin co-treated with zoledronic acid] results in increased activity of CASP3 protein; [vorinostat co-treated with zoledronic acid] results in increased activity of CASP3 protein; [zoledronic acid co-treated with arsenic trioxide] results in increased cleavage of CASP3 protein; [zoledronic acid co-treated with docetaxel] results in decreased expression of CASP3 protein; [zoledronic acid co-treated with Doxorubicin] results in increased expression of CASP3 protein; [zoledronic acid co-treated with Gossypol] results in increased activity of CASP3 protein; vorinostat promotes the reaction [zoledronic acid results in increased activity of CASP3 protein]; zoledronic acid results in increased cleavage of and results in increased activity of CASP3 protein; zoledronic acid results in increased expression of and results in increased activity of CASP3 protein
zoledronic acid results in decreased expression of CASP3 protein
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP3 protein
zoledronic acid results in increased cleavage of CASP3 protein
Zoledronic Acid results in increased expression of CASP3 mRNA
CTD PMID:11986784 PMID:12796698 PMID:17070308 PMID:17562444 PMID:18025282 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Zoledronic Acid results in increased expression of CASP4 mRNA CTD PMID:35587103 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 increases activity ISO zoledronic acid results in increased activity of CASP6 protein CTD PMID:17070308 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO [Tretinoin co-treated with Zoledronic Acid] results in increased activity of CASP7 protein; [Zoledronic Acid co-treated with Gossypol] results in increased activity of CASP7 protein
zoledronic acid results in increased activity of CASP7 protein
CTD PMID:19825521 PMID:20349282 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
ISO zoledronic acid results in increased expression of CASP8 mRNA
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP8 protein
CTD PMID:19036117 PMID:19789217 PMID:20977926 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
affects expression
ISO zoledronic acid results in increased activity of CASP9 protein
[zoledronic acid co-treated with Doxorubicin] results in increased activity of CASP9 protein
zoledronic acid results in increased cleavage of and results in increased activity of CASP9 protein
Zoledronic Acid affects the expression of CASP9 mRNA
CTD PMID:12799645 PMID:19036117 PMID:19789217 PMID:35587103 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casr calcium-sensing receptor decreases expression ISO zoledronic acid results in decreased expression of CASR mRNA CTD PMID:24714768 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression ISO zoledronic acid results in increased expression of CASTOR1 mRNA CTD PMID:24714768 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO zoledronic acid results in decreased expression of CAVIN2 mRNA CTD PMID:24714768 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Cbr1 carbonyl reductase 1 decreases expression ISO Zoledronic Acid results in decreased expression of CBR1 mRNA CTD PMID:24714768 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cbs cystathionine beta synthase decreases expression ISO zoledronic acid results in decreased expression of CBS mRNA CTD PMID:24714768 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cbx5 chromobox 5 increases expression ISO zoledronic acid results in increased expression of CBX5 mRNA CTD PMID:20977926 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO zoledronic acid results in decreased expression of CC2D2A mRNA CTD PMID:24714768 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
JBrowse link
G Ccdc138 coiled-coil domain containing 138 increases expression ISO zoledronic acid results in increased expression of CCDC138 mRNA CTD PMID:20977926 NCBI chr20:26,493,624...26,572,367
Ensembl chr20:26,495,235...26,572,376
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO zoledronic acid promotes the reaction [Gossypol results in decreased expression of CCL2 mRNA]
zoledronic acid results in increased expression of CCL2 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO zoledronic acid results in increased expression of CCL20 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 increases expression ISO zoledronic acid results in increased expression of CCL28 mRNA CTD PMID:24714768 NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
decreases expression
ISO CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein]
Zoledronic Acid results in decreased expression of CCN1 mRNA; Zoledronic Acid results in decreased expression of CCN1 protein
CTD PMID:19530242 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO zoledronic acid results in decreased expression of CCNA2 mRNA CTD PMID:24714768 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 protein
zoledronic acid results in decreased expression of CCNB1 mRNA
CTD PMID:19789217 PMID:20977926 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO zoledronic acid results in decreased expression of CCNB2 mRNA CTD PMID:24714768 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CCND1 mRNA
[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND1 protein
zoledronic acid results in decreased expression of CCND1 protein
CTD PMID:16621245 PMID:19789217 PMID:24714768 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression
ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCND3 protein
zoledronic acid results in decreased expression of CCND3 protein
CTD PMID:19789217 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNE1 protein CTD PMID:19789217 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of CCNE2 mRNA
zoledronic acid results in increased expression of CCNE2 mRNA
CTD PMID:20977926 PMID:25596134 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd14 CD14 molecule increases expression ISO zoledronic acid results in increased expression of CD14 mRNA; zoledronic acid results in increased expression of CD14 protein CTD PMID:24714768 PMID:28871336 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd27 CD27 molecule affects expression ISO zoledronic acid affects the expression of CD27 mRNA CTD PMID:19036117 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd34 CD34 molecule increases expression ISO zoledronic acid results in increased expression of CD34 mRNA CTD PMID:24714768 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
JBrowse link
G Cd40 CD40 molecule increases expression ISO zoledronic acid results in increased expression of CD40 mRNA CTD PMID:24714768 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO zoledronic acid results in decreased expression of CD40LG mRNA CTD PMID:19036117 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd44 CD44 molecule increases expression ISO zoledronic acid results in increased expression of CD44 mRNA CTD PMID:24714768 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO zoledronic acid results in increased expression of CD55 mRNA; zoledronic acid results in increased expression of CD55 protein CTD PMID:20977926 PMID:24714768 PMID:28871336 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd59b CD59b molecule increases expression ISO zoledronic acid results in increased expression of CD59 mRNA CTD PMID:24714768 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cd68 Cd68 molecule increases expression ISO zoledronic acid results in increased expression of CD68 mRNA CTD PMID:24714768 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd69 Cd69 molecule increases expression ISO zoledronic acid results in increased expression of CD69 mRNA CTD PMID:24714768 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd74 CD74 molecule increases expression ISO zoledronic acid results in increased expression of CD74 mRNA CTD PMID:24714768 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd80 Cd80 molecule increases expression ISO zoledronic acid results in increased expression of CD80 protein CTD PMID:19446661 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd83 CD83 molecule increases expression ISO zoledronic acid results in increased expression of CD83 mRNA CTD PMID:24714768 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule increases expression ISO zoledronic acid results in increased expression of CD86 protein CTD PMID:19446661 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc14a cell division cycle 14A increases expression ISO zoledronic acid results in increased expression of CDC14A mRNA CTD PMID:24714768 NCBI chr 2:204,225,540...204,380,927
Ensembl chr 2:204,225,540...204,380,927
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO zoledronic acid results in decreased expression of CDC20 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO zoledronic acid results in increased expression of CDC25C mRNA CTD PMID:20977926 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc26 cell division cycle 26 decreases expression ISO zoledronic acid results in decreased expression of CDC26 protein CTD PMID:28871336 NCBI chr 5:75,844,852...75,859,830 JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO zoledronic acid results in increased abundance of [Guanosine Triphosphate binds to CDC42 protein]
zoledronic acid results in increased expression of [CDC42 protein binds to Guanosine Triphosphate]; zoledronic acid results in increased expression of and affects the localization of CDC42 protein
CTD PMID:16734383 PMID:28871336 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 increases expression ISO zoledronic acid results in increased expression of CDC42EP2 mRNA CTD PMID:24714768 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 increases expression ISO zoledronic acid results in increased expression of CDC42EP5 mRNA CTD PMID:24714768 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Zoledronic Acid results in decreased expression of CDC45 mRNA CTD PMID:24714768 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO zoledronic acid results in increased expression of CDCA5 protein CTD PMID:28871336 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO zoledronic acid results in decreased expression of CDCA7 mRNA CTD PMID:24714768 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO zoledronic acid results in decreased expression of CDCA8 mRNA CTD PMID:24714768 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh4 cadherin 4 increases expression ISO zoledronic acid results in increased expression of CDH4 mRNA CTD PMID:24714768 NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO zoledronic acid results in decreased expression of CDK1 mRNA CTD PMID:24714768 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK2 protein CTD PMID:19789217 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of CDK2AP2 mRNA CTD PMID:16996129 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK4 protein CTD PMID:19789217 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO CCN1 protein affects the reaction [Zoledronic Acid results in increased expression of CDKN1A protein]
zoledronic acid results in increased expression of CDKN1A protein
CTD PMID:19530242 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein; Gefitinib promotes the reaction [[Zoledronic Acid co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of CDKN1B protein]; Zoledronic Acid promotes the reaction [CCN1 protein affects the expression of CDKN1B protein] CTD PMID:16322342 PMID:19530242 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO zoledronic acid results in increased expression of CDKN1C mRNA CTD PMID:20977926 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2aip CDKN2A interacting protein decreases expression ISO zoledronic acid results in decreased expression of CDKN2AIP mRNA CTD PMID:24714768 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO zoledronic acid results in increased expression of CDKN2B mRNA CTD PMID:24714768 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO zoledronic acid results in decreased expression of CDKN3 mRNA CTD PMID:24714768 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO zoledronic acid results in decreased expression of CDT1 mRNA CTD PMID:24714768 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 increases expression ISO zoledronic acid results in increased expression of CDV3 mRNA CTD PMID:20977926 NCBI chr 8:103,934,006...103,947,173
Ensembl chr 8:103,933,996...103,947,192
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression ISO zoledronic acid results in increased expression of CEACAM6 mRNA CTD PMID:24714768 NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO zoledronic acid results in increased expression of CEBPA mRNA CTD PMID:20977926 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO zoledronic acid results in increased expression of CEBPB mRNA CTD PMID:24714768 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO zoledronic acid results in increased expression of CEBPD mRNA CTD PMID:24714768 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cenpa centromere protein A decreases expression ISO zoledronic acid results in decreased expression of CENPA mRNA CTD PMID:24714768 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpf centromere protein F decreases expression
decreases farnesylation
ISO zoledronic acid results in decreased expression of CENPF mRNA
zoledronic acid results in decreased farnesylation of CENPF protein
CTD PMID:20015195 PMID:24714768 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpi centromere protein I increases expression ISO zoledronic acid results in increased expression of CENPI mRNA CTD PMID:20977926 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657
JBrowse link
G Cenpm centromere protein M decreases expression ISO zoledronic acid results in decreased expression of CENPM mRNA CTD PMID:24714768 NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258
JBrowse link
G Cep120 centrosomal protein 120 increases expression ISO zoledronic acid results in increased expression of CEP120 mRNA CTD PMID:20977926 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964
JBrowse link
G Cep20 centrosomal protein 20 increases expression ISO Zoledronic Acid results in increased expression of CEP20 mRNA CTD PMID:20977926 NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837
JBrowse link
G Cep295 centrosomal protein 295 increases expression ISO zoledronic acid results in increased expression of CEP295 mRNA CTD PMID:20977926 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO zoledronic acid results in decreased expression of CEP55 mRNA CTD PMID:24714768 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Cep57 centrosomal protein 57 increases expression ISO zoledronic acid results in increased expression of CEP57 mRNA CTD PMID:20977926 NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 increases expression ISO zoledronic acid results in increased expression of CEPT1 mRNA CTD PMID:24714768 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Cfb complement factor B increases expression ISO zoledronic acid results in increased expression of CFB mRNA CTD PMID:24714768 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfl1 cofilin 1 increases expression ISO zoledronic acid results in increased expression of CFL1 protein CTD PMID:28871336 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO zoledronic acid results in increased expression of CFLAR mRNA CTD PMID:24714768 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cgn cingulin decreases expression ISO zoledronic acid results in decreased expression of CGN mRNA CTD PMID:24714768 NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
JBrowse link
G Cgnl1 cingulin-like 1 decreases expression ISO zoledronic acid results in decreased expression of CGNL1 mRNA CTD PMID:24714768 NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO zoledronic acid results in increased expression of CHAC1 mRNA CTD PMID:20977926 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chmp4b charged multivesicular body protein 4B increases expression ISO zoledronic acid results in increased expression of CHMP4B mRNA CTD PMID:20977926 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G Chmp6 charged multivesicular body protein 6 increases expression ISO zoledronic acid results in increased expression of CHMP6 protein CTD PMID:28871336 NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640
JBrowse link
G Chst4 carbohydrate sulfotransferase 4 increases expression ISO zoledronic acid results in increased expression of CHST4 mRNA CTD PMID:24714768 NCBI chr19:37,993,471...38,002,123
Ensembl chr19:37,991,417...38,003,608
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO zoledronic acid results in increased expression of CIITA mRNA CTD PMID:24714768 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cimip2c ciliary microtubule inner protein 2C decreases expression ISO Zoledronic Acid results in decreased expression of CIMIP2C mRNA CTD PMID:24714768 NCBI chr 6:25,905,294...25,923,615
Ensembl chr 6:25,905,294...25,923,615
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of CKS2 mRNA CTD PMID:16996129 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clcn5 chloride voltage-gated channel 5 decreases expression ISO zoledronic acid results in decreased expression of CLCN5 mRNA CTD PMID:24714768 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression ISO zoledronic acid results in decreased expression of CLCNKA mRNA CTD PMID:24714768 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases expression ISO zoledronic acid results in decreased expression of CLCNKB mRNA CTD PMID:24714768 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Cldn14 claudin 14 increases expression ISO zoledronic acid results in increased expression of CLDN14 mRNA CTD PMID:24714768 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Cldn16 claudin 16 decreases expression ISO zoledronic acid results in decreased expression of CLDN16 mRNA CTD PMID:24714768 NCBI chr11:74,290,298...74,309,588
Ensembl chr11:74,290,298...74,309,588
JBrowse link
G Cldn2 claudin 2 decreases expression ISO zoledronic acid results in decreased expression of CLDN2 mRNA CTD PMID:24714768 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn3 claudin 3 increases expression ISO zoledronic acid results in increased expression of CLDN3 mRNA CTD PMID:20977926 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO zoledronic acid results in increased expression of CLEC4E mRNA CTD PMID:24714768 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin increases expression ISO zoledronic acid results in increased expression of CLN3 mRNA CTD PMID:24714768 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 increases expression ISO zoledronic acid results in increased expression of CNGB1 mRNA CTD PMID:24714768 NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173
JBrowse link
G Cntnap1 contactin associated protein 1 increases expression ISO zoledronic acid results in increased expression of CNTNAP1 mRNA CTD PMID:24714768 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
JBrowse link
G Col16a1 collagen type XVI alpha 1 chain increases expression ISO zoledronic acid results in increased expression of COL16A1 mRNA CTD PMID:24714768 NCBI chr 5:142,388,376...142,442,825
Ensembl chr 5:142,388,426...142,442,825
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO zoledronic acid results in decreased expression of COL18A1 mRNA CTD PMID:24714768 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
increases expression
ISO zoledronic acid results in decreased expression of COL1A1 mRNA; zoledronic acid results in decreased expression of COL1A1 protein
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]
CTD PMID:19597852 PMID:28871336 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions
ISO zoledronic acid results in increased expression of COL3A1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]
CTD PMID:28871336 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression
multiple interactions
ISO zoledronic acid results in increased expression of COL4A1 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]
CTD PMID:28871336 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col4a3 collagen type IV alpha 3 chain decreases expression ISO zoledronic acid results in decreased expression of COL4A3 mRNA CTD PMID:24714768 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression ISO zoledronic acid results in decreased expression of COL4A5 mRNA CTD PMID:24714768 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO zoledronic acid results in increased expression of COL5A1 protein CTD PMID:28871336 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Col9a2 collagen type IX alpha 2 chain increases expression ISO zoledronic acid results in increased expression of COL9A2 mRNA CTD PMID:24714768 NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677
JBrowse link
G Comp cartilage oligomeric matrix protein increases expression ISO zoledronic acid results in increased expression of COMP protein CTD PMID:28871336 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO zoledronic acid results in decreased expression of COQ3 mRNA CTD PMID:24714768 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coq4 coenzyme Q4 decreases expression ISO zoledronic acid results in decreased expression of COQ4 mRNA CTD PMID:20977926 NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO zoledronic acid results in decreased expression of COX17 mRNA CTD PMID:20977926 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cp ceruloplasmin increases expression ISO zoledronic acid results in increased expression of CP mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpa4 carboxypeptidase A4 decreases expression ISO zoledronic acid results in decreased expression of CPA4 mRNA CTD PMID:24714768 NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255
JBrowse link
G Cpd carboxypeptidase D increases expression ISO zoledronic acid results in increased expression of CPD mRNA CTD PMID:20977926 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 decreases expression ISO zoledronic acid results in decreased expression of CPEB2 mRNA CTD PMID:24714768 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
JBrowse link
G Cpne3 copine 3 increases expression ISO zoledronic acid results in increased expression of CPNE3 mRNA CTD PMID:20977926 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
JBrowse link
G Cpne8 copine 8 decreases expression ISO zoledronic acid results in decreased expression of CPNE8 mRNA CTD PMID:24714768 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Cpq carboxypeptidase Q decreases expression ISO zoledronic acid results in decreased expression of PGCP mRNA CTD PMID:24714768 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CPT1A mRNA; zoledronic acid results in decreased expression of CPT1A protein
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]
CTD PMID:28871336 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of CPT2 mRNA
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]; SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]
CTD PMID:28871336 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Cpvl carboxypeptidase, vitellogenic-like decreases expression ISO zoledronic acid results in decreased expression of CPVL mRNA CTD PMID:24714768 NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655
JBrowse link
G Crat carnitine O-acetyltransferase decreases expression ISO zoledronic acid results in decreased expression of CRAT mRNA CTD PMID:28871336 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO zoledronic acid results in decreased expression of CREB5 mRNA CTD PMID:24714768 NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression ISO zoledronic acid results in decreased expression of CRLS1 mRNA CTD PMID:20977926 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Cryab crystallin, alpha B increases expression ISO zoledronic acid results in increased expression of CRYAB mRNA CTD PMID:24714768 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csf1 colony stimulating factor 1 increases expression
decreases expression
ISO zoledronic acid results in increased expression of CSF1 mRNA
zoledronic acid results in decreased expression of CSF1 mRNA
CTD PMID:20977926 PMID:24714768 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO zoledronic acid results in increased expression of CSF2 mRNA CTD PMID:24714768 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO zoledronic acid results in decreased expression of CSRP2 mRNA CTD PMID:24714768 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cst3 cystatin C increases expression ISO zoledronic acid results in increased expression of CST3 protein CTD PMID:28871336 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Ctbs chitobiase increases expression ISO zoledronic acid results in increased expression of CTBS mRNA CTD PMID:20977926 NCBI chr 2:235,340,520...235,355,091
Ensembl chr 2:235,340,547...235,355,091
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO zoledronic acid results in decreased expression of CTH mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctsb cathepsin B decreases expression ISO zoledronic acid results in decreased expression of CTSB protein CTD PMID:16475674 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsc cathepsin C increases expression ISO zoledronic acid results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctse cathepsin E increases expression ISO zoledronic acid results in increased expression of CTSE mRNA CTD PMID:24714768 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
JBrowse link
G Ctss cathepsin S increases expression ISO zoledronic acid results in increased expression of CTSS mRNA CTD PMID:24714768 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cttn cortactin decreases expression ISO zoledronic acid results in decreased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 decreases expression ISO zoledronic acid results in decreased expression of CTU2 mRNA CTD PMID:20977926 NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623
JBrowse link
G Cubn cubilin increases expression ISO zoledronic acid results in increased expression of CUBN mRNA CTD PMID:24714768 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cul4a cullin 4A increases expression ISO zoledronic acid results in increased expression of CUL4A mRNA CTD PMID:24714768 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO zoledronic acid results in increased expression of CX3CL1 mRNA CTD PMID:24714768 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA
zoledronic acid results in increased expression of CXCL1 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO zoledronic acid results in increased expression of CXCL10 mRNA CTD PMID:24714768 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO zoledronic acid results in decreased expression of CXCL12 mRNA CTD PMID:24714768 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO zoledronic acid results in decreased expression of CXCL14 mRNA CTD PMID:24714768 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 increases expression ISO zoledronic acid results in increased expression of CXCL16 mRNA CTD PMID:24714768 NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO zoledronic acid results in increased expression of CXCL2 mRNA CTD PMID:24714768 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of CXCL1 mRNA
zoledronic acid results in increased expression of CXCL1 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO zoledronic acid results in increased expression of CXCR4 mRNA CTD PMID:24714768 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression ISO zoledronic acid results in increased expression of CYB5R3 mRNA CTD PMID:20977926 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Zoledronic Acid results in increased expression of CYCS mRNA CTD PMID:35587103 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 decreases expression ISO zoledronic acid results in decreased expression of CYFIP2 mRNA CTD PMID:24714768 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP1A1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO zoledronic acid results in increased expression of CYP1A2 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP1B1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO zoledronic acid results in increased expression of CYP3A5 mRNA CTD PMID:24714768 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression ISO zoledronic acid results in increased expression of CYP4B1 mRNA CTD PMID:24714768 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO zoledronic acid results in increased expression of CYP51A1 mRNA CTD PMID:24714768 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410
JBrowse link
G Cys1 cystin 1 decreases expression ISO zoledronic acid results in decreased expression of CYS1 mRNA CTD PMID:24714768 NCBI chr 6:41,300,836...41,318,071
Ensembl chr 6:41,300,836...41,318,071
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO zoledronic acid results in increased expression of CYTIP mRNA CTD PMID:24714768 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO zoledronic acid results in decreased expression of DAPK1 mRNA CTD PMID:19036117 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO zoledronic acid results in increased expression of DAPP1 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423
JBrowse link
G Dcaf15 DDB1 and CUL4 associated factor 15 increases expression ISO zoledronic acid results in increased expression of DCAF15 mRNA CTD PMID:20977926 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277
JBrowse link
G Dcdc2 doublecortin domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of DCDC2 mRNA CTD PMID:24714768 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 increases expression ISO zoledronic acid results in increased expression of DCUN1D4 mRNA CTD PMID:20977926 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO zoledronic acid results in decreased expression of DDAH1 mRNA CTD PMID:24714768 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Zoledronic Acid results in increased expression of DDIT3 mRNA CTD PMID:35587103 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO zoledronic acid results in decreased expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO zoledronic acid results in increased expression of DDIT4L mRNA CTD PMID:24714768 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression
decreases expression
ISO zoledronic acid results in increased expression of DDR1 mRNA
zoledronic acid monohydrate decreases expression of DDR1 mRNA and protein in human PC3 cancer cell line
CTD
RGD
PMID:24714768 PMID:26366216 RGD:151347692 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddx10 DEAD-box helicase 10 decreases expression ISO zoledronic acid results in decreased expression of DDX10 mRNA CTD PMID:24714768 NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
JBrowse link
G Ddx42 DEAD-box helicase 42 increases expression ISO zoledronic acid results in increased expression of DDX42 mRNA CTD PMID:20977926 NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939
JBrowse link
G Defb1 defensin beta 1 increases expression ISO zoledronic acid results in increased expression of DEFB1 mRNA CTD PMID:24714768 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Defb5 defensin beta 5 increases expression ISO Zoledronic Acid results in increased expression of DEFB4 mRNA CTD PMID:24714768 NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
JBrowse link
G Dennd2a DENN domain containing 2A decreases expression ISO zoledronic acid results in decreased expression of DENND2A mRNA CTD PMID:24714768 NCBI chr 4:68,233,016...68,332,235
Ensembl chr 4:68,233,958...68,332,105
JBrowse link
G Dennd2b DENN domain containing 2B increases expression ISO Zoledronic Acid results in increased expression of DENND2B mRNA CTD PMID:24714768 NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680
JBrowse link
G Dennd2d DENN domain containing 2D increases expression ISO zoledronic acid results in increased expression of DENND2D mRNA CTD PMID:24714768 NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression ISO zoledronic acid results in decreased expression of DEPDC1 mRNA CTD PMID:24714768 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO zoledronic acid results in increased expression of DEPP1 mRNA CTD PMID:24714768 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Zoledronic Acid results in decreased expression of DEPTOR mRNA CTD PMID:24714768 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO zoledronic acid results in decreased expression of DFFA mRNA CTD PMID:20977926 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO zoledronic acid results in increased expression of DHCR7 mRNA CTD PMID:24714768 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO zoledronic acid results in decreased expression of DHRS11 mRNA CTD PMID:24714768 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression ISO zoledronic acid results in decreased expression of DHRS3 mRNA CTD PMID:24714768 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dhx35 DEAH-box helicase 35 increases expression ISO zoledronic acid results in increased expression of DHX35 mRNA CTD PMID:20977926 NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Tretinoin co-treated with zoledronic acid] results in decreased expression of DIABLO protein CTD PMID:20349282 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression ISO zoledronic acid results in decreased expression of DIAPH3 mRNA CTD PMID:24714768 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO zoledronic acid results in decreased expression of DIO2 mRNA CTD PMID:24714768 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO zoledronic acid results in decreased expression of DKK1 mRNA CTD PMID:24714768 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein decreases expression ISO zoledronic acid results in decreased expression of DLC1 mRNA CTD PMID:24714768 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 increases expression ISO zoledronic acid results in increased expression of DLG1 mRNA CTD PMID:20977926 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dlgap4 DLG associated protein 4 decreases expression ISO zoledronic acid results in decreased expression of DLGAP4 mRNA CTD PMID:20977926 NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO zoledronic acid results in decreased expression of DLGAP5 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO zoledronic acid results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO zoledronic acid results in increased expression of DNAJB9 mRNA CTD PMID:20977926 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnase1l1 deoxyribonuclease 1-like 1 increases expression ISO zoledronic acid results in increased expression of DNASE1L1 mRNA CTD PMID:20977926 NCBI chr  X:152,056,942...152,065,518
Ensembl chr  X:152,056,942...152,065,518
JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO zoledronic acid results in increased expression of DNER mRNA CTD PMID:24714768 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO zoledronic acid results in increased expression of DOCK10 mRNA CTD PMID:24714768 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
JBrowse link
G Dpp9 dipeptidyl peptidase 9 increases expression ISO zoledronic acid results in increased expression of DPP9 mRNA CTD PMID:20977926 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541
JBrowse link
G Dse dermatan sulfate epimerase increases expression ISO zoledronic acid results in increased expression of DSE mRNA CTD PMID:24714768 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dsel dermatan sulfate epimerase-like decreases expression ISO zoledronic acid results in decreased expression of DSEL mRNA CTD PMID:24714768 NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647
JBrowse link
G Dtwd2 DTW domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of DTWD2 mRNA CTD PMID:20977926 NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832
JBrowse link
G Dtx3 deltex E3 ubiquitin ligase 3 increases expression ISO zoledronic acid results in increased expression of DTX3 mRNA CTD PMID:20977926 NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
JBrowse link
G Dusp18 dual specificity phosphatase 18 increases expression ISO zoledronic acid results in increased expression of DUSP18 mRNA CTD PMID:20977926 NCBI chr14:78,790,183...78,811,576
Ensembl chr14:78,787,505...78,811,576
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO zoledronic acid results in decreased expression of DUSP4 mRNA CTD PMID:24714768 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO zoledronic acid results in decreased expression of DUSP5 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO zoledronic acid results in decreased expression of DUSP6 mRNA CTD PMID:24714768 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 decreases expression ISO zoledronic acid results in decreased expression of DYNC2LI1 mRNA CTD PMID:24714768 NCBI chr 6:9,992,537...10,025,355
Ensembl chr 6:9,992,541...10,025,336
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO zoledronic acid results in increased expression of E2F2 mRNA CTD PMID:20977926 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression ISO zoledronic acid results in increased expression of EBI3 mRNA CTD PMID:24714768 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression ISO zoledronic acid results in increased expression of EBP mRNA CTD PMID:24714768 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression ISO zoledronic acid results in increased expression of ECE1 mRNA CTD PMID:24714768 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO zoledronic acid results in decreased expression of ECH1 mRNA CTD PMID:28871336 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO zoledronic acid results in increased expression of ECM1 mRNA CTD PMID:24714768 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
JBrowse link
G Edn1 endothelin 1 increases expression ISO zoledronic acid results in increased expression of EDN1 mRNA CTD PMID:24714768 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Efhd1 EF-hand domain family, member D1 decreases expression ISO zoledronic acid results in decreased expression of EFHD1 mRNA CTD PMID:24714768 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
JBrowse link
G Efna1 ephrin A1 increases expression ISO zoledronic acid results in increased expression of EFNA1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Efnb2 ephrin B2 decreases expression ISO zoledronic acid results in decreased expression of EFNB2 mRNA CTD PMID:24714768 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Egfl6 EGF-like-domain, multiple 6 decreases expression ISO zoledronic acid results in decreased expression of EGFL6 mRNA CTD PMID:24714768 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases expression ISO zoledronic acid results in increased expression of EGLN2 mRNA CTD PMID:20977926 NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751
JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression
ISO zoledronic acid results in increased expression of EGR1 mRNA
zoledronic acid results in decreased expression of EGR1 mRNA
CTD PMID:20977926 PMID:24714768 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO zoledronic acid results in increased expression of EGR2 mRNA CTD PMID:20977926 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr4 early growth response 4 increases expression ISO zoledronic acid results in increased expression of EGR4 mRNA CTD PMID:20977926 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression ISO zoledronic acid results in decreased expression of EHHADH mRNA CTD PMID:28871336 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO zoledronic acid results in increased expression of ELK1 mRNA CTD PMID:20977926 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO zoledronic acid results in increased expression of ELL2 mRNA CTD PMID:20977926 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Elob elongin B decreases expression ISO zoledronic acid results in decreased expression of ELOB mRNA CTD PMID:24714768 NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO zoledronic acid results in increased expression of ELOVL6 mRNA CTD PMID:24714768 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Eml4 EMAP like 4 increases expression ISO zoledronic acid results in increased expression of EML4 mRNA CTD PMID:20977926 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Emp3 epithelial membrane protein 3 multiple interactions
increases expression
ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of EMP3 mRNA
zoledronic acid results in increased expression of EMP3 mRNA
CTD PMID:16996129 PMID:20977926 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 increases expression ISO zoledronic acid results in increased expression of ENPP6 mRNA CTD PMID:24714768 NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO zoledronic acid results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
JBrowse link
G Epha4 Eph receptor A4 increases expression ISO zoledronic acid results in increased expression of EPHA4 mRNA CTD PMID:24714768 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Ephb3 Eph receptor B3 decreases expression ISO zoledronic acid results in decreased expression of EPHB3 mRNA CTD PMID:24714768 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370
JBrowse link
G Ephb4 EPH receptor B4 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of EPHB4 mRNA CTD PMID:19825521 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of EPHX2 mRNA
zoledronic acid results in increased expression of EPHX2 protein
CTD PMID:24714768 PMID:28871336 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 decreases expression ISO Zoledronic Acid results in decreased expression of EPRS1 mRNA CTD PMID:25596134 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
JBrowse link
G Epsti1 epithelial stromal interaction 1 increases expression ISO zoledronic acid results in increased expression of EPSTI1 mRNA CTD PMID:24714768 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ERCC5 mRNA CTD PMID:16996129 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Erg ETS transcription factor ERG multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of ERG mRNA CTD PMID:16996129 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871
JBrowse link
G Ergic2 ERGIC and golgi 2 decreases expression ISO zoledronic acid results in decreased expression of ERGIC2 mRNA CTD PMID:20977926 NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:181,090,808...181,123,060
JBrowse link
G Erlin1 ER lipid raft associated 1 increases expression ISO zoledronic acid results in increased expression of ERLIN1 mRNA CTD PMID:20977926 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Zoledronic Acid results in increased expression of ERN1 mRNA; Zoledronic Acid results in increased expression of ERN1 protein CTD PMID:35587103 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Zoledronic Acid results in increased expression of ERO1A mRNA CTD PMID:24714768 PMID:25596134 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Erp27 endoplasmic reticulum protein 27 increases expression ISO zoledronic acid results in increased expression of ERP27 mRNA CTD PMID:24714768 NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO zoledronic acid results in increased expression of ESCO2 mRNA CTD PMID:20977926 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Esrrg estrogen-related receptor gamma decreases expression ISO zoledronic acid results in decreased expression of ESRRG mRNA CTD PMID:24714768 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO zoledronic acid results in increased expression of ETS1 mRNA CTD PMID:24714768 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO zoledronic acid results in decreased expression of ETS2 mRNA CTD PMID:24714768 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Etv4 ETS variant transcription factor 4 decreases expression ISO zoledronic acid results in decreased expression of ETV4 mRNA CTD PMID:24714768 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death decreases expression ISO zoledronic acid results in decreased expression of EVA1A mRNA CTD PMID:24714768 NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011
JBrowse link
G Exoc5 exocyst complex component 5 increases expression ISO zoledronic acid results in increased expression of EXOC5 mRNA CTD PMID:20977926 NCBI chr15:22,310,682...22,355,695
Ensembl chr15:22,308,946...22,355,335
JBrowse link
G Ezr ezrin increases expression ISO zoledronic acid results in increased expression of EZR mRNA CTD PMID:20977926 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO zoledronic acid results in decreased expression of F3 mRNA CTD PMID:24714768 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Zoledronic Acid results in increased expression of FABP1 mRNA CTD PMID:35587103 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [Tretinoin co-treated with zoledronic acid] results in increased expression of FADD protein CTD PMID:20349282 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fads2 fatty acid desaturase 2 increases expression ISO zoledronic acid results in increased expression of FADS2 mRNA CTD PMID:24714768 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO zoledronic acid results in increased expression of FADS3 mRNA CTD PMID:20977926 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression ISO zoledronic acid results in increased expression of FAM107A mRNA CTD PMID:24714768 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fam167a family with sequence similarity 167, member A decreases expression ISO zoledronic acid results in decreased expression of FAM167A mRNA CTD PMID:25596134 NCBI chr15:37,685,221...37,715,472
Ensembl chr15:37,700,919...37,715,469
JBrowse link
G Fam171b family with sequence similarity 171, member B decreases expression ISO zoledronic acid results in decreased expression of FAM171B mRNA CTD PMID:24714768 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase increases expression ISO zoledronic acid results in increased expression of FAM20A mRNA CTD PMID:24714768 NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672
JBrowse link
G Fam222b family with sequence similarity 222, member B decreases expression ISO zoledronic acid results in decreased expression of FAM222B mRNA CTD PMID:20977926 NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350
JBrowse link
G Fam43a family with sequence similarity 43, member A decreases expression ISO zoledronic acid results in decreased expression of FAM43A mRNA CTD PMID:24714768 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO zoledronic acid results in increased expression of FAS mRNA
[Tretinoin co-treated with zoledronic acid] results in increased expression of FAS protein
CTD PMID:19036117 PMID:20349282 PMID:25596134 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand affects expression ISO zoledronic acid affects the expression of FASLG mRNA CTD PMID:19036117 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fblim1 filamin binding LIM protein 1 decreases expression ISO zoledronic acid results in decreased expression of FBLIM1 protein CTD PMID:28871336 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
JBrowse link
G Fbln1 fibulin 1 increases expression ISO zoledronic acid results in increased expression of FBLN1 mRNA; zoledronic acid results in increased expression of FBLN1 protein CTD PMID:24714768 PMID:28871336 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fbln5 fibulin 5 increases expression ISO zoledronic acid results in increased expression of FBLN5 mRNA CTD PMID:24714768 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755
JBrowse link
G Fbn1 fibrillin 1 increases expression ISO zoledronic acid results in increased expression of FBN1 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fcgbp Fc gamma binding protein increases expression ISO zoledronic acid results in increased expression of FCGBP mRNA CTD PMID:24714768 NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083
JBrowse link
G Fcgrt Fc gamma receptor and transporter decreases expression ISO zoledronic acid results in decreased expression of FCGRT mRNA CTD PMID:24714768 NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
JBrowse link
G Fcmr Fc mu receptor increases expression ISO zoledronic acid results in increased expression of FCMR mRNA CTD PMID:24714768 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Fcrl2 Fc receptor-like 2 increases expression ISO zoledronic acid results in increased expression of FCRL2 mRNA CTD PMID:24714768 NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
JBrowse link
G Fcrla Fc receptor-like A increases expression ISO zoledronic acid results in increased expression of FCRLA mRNA CTD PMID:24714768 NCBI chr13:83,160,453...83,170,170
Ensembl chr13:83,160,398...83,170,762
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions
increases expression
ISO
EXP
[zoledronic acid co-treated with fluvastatin] results in increased expression of FDFT1 mRNA
zoledronic acid results in increased expression of FDFT1 mRNA
CTD PMID:16996129 PMID:18325729 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase affects binding
decreases activity
multiple interactions
increases activity
increases expression
ISO
EXP
zoledronic acid binds to FDPS protein
zoledronic acid results in decreased activity of FDPS protein
[zoledronic acid results in decreased activity of FDPS protein] which results in increased abundance of isopentenyl pyrophosphate
zoledronic acid results in increased activity of FDPS protein
zoledronic acid results in increased expression of FDPS mRNA
CTD PMID:11160603 PMID:12846887 PMID:16684881 PMID:17208200 PMID:18325729 More... NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fech ferrochelatase decreases expression ISO zoledronic acid results in decreased expression of FECH mRNA CTD PMID:24714768 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fem1b fem-1 homolog B increases expression ISO zoledronic acid results in increased expression of FEM1B mRNA CTD PMID:20977926 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression ISO zoledronic acid results in increased expression of FEZ1 mRNA CTD PMID:24714768 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Fgf18 fibroblast growth factor 18 increases expression ISO zoledronic acid results in increased expression of FGF18 mRNA CTD PMID:24714768 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
multiple interactions
ISO zoledronic acid results in decreased expression of FGF2 mRNA
zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGF2 mRNA]
CTD PMID:19825521 PMID:24714768 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf9 fibroblast growth factor 9 decreases expression ISO zoledronic acid results in decreased expression of FGF9 mRNA CTD PMID:24714768 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 increases expression ISO zoledronic acid results in increased expression of FGFBP1 mRNA CTD PMID:24714768 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions
decreases expression
ISO zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGFR3 mRNA]
zoledronic acid results in decreased expression of FGFR3 mRNA
CTD PMID:19825521 PMID:24714768 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO zoledronic acid results in decreased expression of FGFR4 mRNA CTD PMID:24714768 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fgl2 fibrinogen-like 2 decreases expression ISO zoledronic acid results in decreased expression of FGL2 mRNA CTD PMID:24714768 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression ISO zoledronic acid results in increased expression of FHL1 mRNA CTD PMID:20977926 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO zoledronic acid results in decreased expression of FHL2 mRNA CTD PMID:24714768 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fignl1 fidgetin-like 1 increases expression ISO zoledronic acid results in increased expression of FIGNL1 mRNA CTD PMID:20977926 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
JBrowse link
G Filip1l filamin A interacting protein 1-like decreases expression ISO zoledronic acid results in decreased expression of FILIP1L mRNA CTD PMID:24714768 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
JBrowse link
G Fjx1 four-jointed box kinase 1 decreases expression ISO zoledronic acid results in decreased expression of FJX1 mRNA CTD PMID:24714768 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression ISO zoledronic acid results in increased expression of FKBP1A mRNA CTD PMID:24714768 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fmnl3 formin-like 3 increases expression ISO zoledronic acid results in increased expression of FMNL3 mRNA CTD PMID:24714768 NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [zoledronic acid results in increased expression of FN1 protein]
Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of FN1 protein]; SLC27A2 gene mutant form inhibits the reaction [Zoledronic Acid results in increased expression of FN1 mRNA]; SLC27A2 gene mutant form inhibits the reaction [Zoledronic Acid results in increased expression of FN1 protein]
zoledronic acid results in increased expression of FN1 mRNA; zoledronic acid results in increased expression of FN1 protein
CTD PMID:28871336 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO zoledronic acid results in increased expression of FNBP1 mRNA CTD PMID:24714768 NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881
JBrowse link
G Fnta farnesyltransferase, CAAX box, subunit alpha multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of FNTA mRNA CTD PMID:16996129 NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO zoledronic acid results in decreased expression of FOLR1 mRNA CTD PMID:24714768 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO
EXP
zoledronic acid results in decreased expression of FOS mRNA
zoledronic acid results in decreased expression of FOS protein
zoledronic acid inhibits the reaction [Freund's Adjuvant results in increased expression of FOS protein]
CTD PMID:16769263 PMID:17323179 PMID:24714768 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxj1 forkhead box J1 decreases expression ISO zoledronic acid results in decreased expression of FOXJ1 mRNA CTD PMID:24714768 NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237
JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO zoledronic acid results in decreased expression of FOXO1 mRNA CTD PMID:24714768 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression ISO zoledronic acid results in decreased expression of FREM2 mRNA CTD PMID:25596134 NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785
JBrowse link
G Frk fyn-related Src family tyrosine kinase increases expression ISO zoledronic acid results in increased expression of FRK mRNA CTD PMID:24714768 NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO zoledronic acid results in increased expression of FSCN1 mRNA CTD PMID:20977926 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like increases expression ISO zoledronic acid results in increased expression of FSD1L mRNA CTD PMID:24714768 NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928
JBrowse link
G Fstl1 follistatin-like 1 increases expression ISO zoledronic acid results in increased expression of FSTL1 mRNA CTD PMID:24714768 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fstl3 follistatin like 3 decreases expression ISO zoledronic acid results in decreased expression of FSTL3 mRNA CTD PMID:24714768 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO zoledronic acid results in increased expression of FTH1 mRNA CTD PMID:25596134 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Fuca1 alpha-L-fucosidase 1 increases expression ISO zoledronic acid results in increased expression of FUCA1 mRNA CTD PMID:24714768 NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO zoledronic acid results in increased expression of FUT8 mRNA CTD PMID:24714768 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 decreases expression ISO zoledronic acid results in decreased expression of FXYD2 mRNA CTD PMID:24714768 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G Fyb1 FYN binding protein 1 decreases expression ISO zoledronic acid results in decreased expression of FYB1 mRNA CTD PMID:24714768 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Fzd5 frizzled class receptor 5 increases expression ISO zoledronic acid results in increased expression of FZD5 mRNA CTD PMID:24714768 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO zoledronic acid results in decreased expression of GABARAPL1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi decreases expression ISO zoledronic acid results in decreased expression of GABRP mRNA CTD PMID:24714768 NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO zoledronic acid results in decreased expression of GADD45A mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions
increases expression
ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of GADD45B mRNA
zoledronic acid results in increased expression of GADD45B mRNA
CTD PMID:16996129 PMID:20977926 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO zoledronic acid results in increased expression of GADD45G mRNA CTD PMID:24714768 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 decreases expression ISO zoledronic acid results in decreased expression of GALNT10 mRNA CTD PMID:24714768 NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 decreases expression ISO zoledronic acid results in decreased expression of GALNT11 mRNA CTD PMID:24714768 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 decreases expression ISO zoledronic acid results in decreased expression of GALNT16 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
JBrowse link
G Galnt18 polypeptide N-acetylgalactosaminyltransferase 18 increases expression ISO Zoledronic Acid results in increased expression of GALNT18 mRNA CTD PMID:24714768 NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO zoledronic acid results in increased expression of GBP2 mRNA CTD PMID:24714768 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gbp4 guanylate binding protein 4 increases expression ISO Zoledronic Acid results in increased expression of GBP4 mRNA CTD PMID:24714768 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
JBrowse link
G Gbp5 guanylate binding protein 5 increases expression ISO zoledronic acid results in increased expression of GBP5 mRNA CTD PMID:24714768 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Gc GC, vitamin D binding protein increases expression ISO zoledronic acid results in increased expression of GC protein CTD PMID:28871336 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 decreases expression ISO zoledronic acid results in decreased expression of GCNT1 mRNA CTD PMID:24714768 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO zoledronic acid results in increased expression of GCNT3 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO zoledronic acid results in decreased expression of GDF15 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression ISO zoledronic acid results in increased expression of GDI2 protein CTD PMID:28871336 NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle decreases expression ISO zoledronic acid results in decreased expression of GEM mRNA CTD PMID:24714768 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 decreases activity ISO zoledronic acid results in decreased activity of GGPS1 protein CTD PMID:17208200 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression ISO zoledronic acid results in decreased expression of GGT1 mRNA CTD PMID:24714768 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO zoledronic acid results in decreased expression of GINS2 mRNA CTD PMID:24714768 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression ISO zoledronic acid results in decreased expression of GJB1 mRNA CTD PMID:24714768 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO zoledronic acid results in increased expression of GJB2 mRNA CTD PMID:24714768 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gk glycerol kinase increases expression ISO zoledronic acid results in increased expression of GK mRNA CTD PMID:20977926 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gla galactosidase, alpha decreases expression ISO zoledronic acid results in decreased expression of GLA protein CTD PMID:28871336 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glce glucuronic acid epimerase increases expression ISO zoledronic acid results in increased expression of GLCE mRNA CTD PMID:24714768 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Glg1 golgi glycoprotein 1 decreases expression ISO zoledronic acid results in decreased expression of GLG1 mRNA CTD PMID:20977926 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Glipr1 GLI pathogenesis-related 1 decreases expression ISO zoledronic acid results in decreased expression of GLIPR1 mRNA CTD PMID:20977926 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
JBrowse link
G Glrx3 glutaredoxin 3 decreases expression ISO zoledronic acid results in decreased expression of GLRX3 mRNA CTD PMID:20977926 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Gnb2 G protein subunit beta 2 increases expression ISO zoledronic acid results in increased expression of GNB2 protein CTD PMID:28871336 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO zoledronic acid results in increased expression of GNB4 mRNA CTD PMID:20977926 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gng10 G protein subunit gamma 10 increases expression ISO zoledronic acid results in increased expression of GNG10 protein CTD PMID:28871336 NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012
Ensembl chr 5:73,856,164...73,863,012
JBrowse link
G Gng7 G protein subunit gamma 7 decreases expression ISO zoledronic acid results in decreased expression of GNG7 mRNA CTD PMID:24714768 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Golt1a golgi transport 1A decreases expression ISO zoledronic acid results in decreased expression of GOLT1A mRNA CTD PMID:24714768 NCBI chr13:44,760,356...44,773,123
Ensembl chr13:44,760,380...44,773,122
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO zoledronic acid results in increased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpc3 glypican 3 decreases expression ISO zoledronic acid results in decreased expression of GPC3 mRNA CTD PMID:24714768 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpc4 glypican 4 decreases expression ISO zoledronic acid results in decreased expression of GPC4 mRNA CTD PMID:24714768 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO zoledronic acid results in decreased expression of GPNMB mRNA CTD PMID:24714768 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr141 G protein-coupled receptor 141 increases expression ISO zoledronic acid results in increased expression of GPR141 mRNA CTD PMID:24714768 NCBI chr17:45,117,818...45,180,053
Ensembl chr17:45,117,812...45,180,027
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 increases expression ISO zoledronic acid results in increased expression of GPR37L1 mRNA CTD PMID:24714768 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO zoledronic acid results in decreased expression of GPRC5A mRNA CTD PMID:24714768 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Grb14 growth factor receptor bound protein 14 decreases expression ISO zoledronic acid results in decreased expression of GRB14 mRNA CTD PMID:24714768 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression ISO zoledronic acid results in increased expression of GRIP2 mRNA CTD PMID:24714768 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO zoledronic acid results in increased expression of GRK5 mRNA CTD PMID:24714768 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Grm8 glutamate metabotropic receptor 8 decreases expression ISO zoledronic acid results in decreased expression of GRM8 mRNA CTD PMID:24714768 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Gtf2i general transcription factor II I increases expression ISO zoledronic acid results in increased expression of GTF2I mRNA CTD PMID:20977926 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 decreases expression ISO zoledronic acid results in decreased expression of GTF2IRD1 mRNA CTD PMID:24714768 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
JBrowse link
G Gtf3c4 general transcription factor IIIC subunit 4 increases expression ISO zoledronic acid results in increased expression of GTF3C4 mRNA CTD PMID:20977926 NCBI chr 3:12,154,803...12,172,795
Ensembl chr 3:12,154,805...12,172,725
JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO zoledronic acid results in increased expression of GTPBP2 mRNA CTD PMID:20977926 NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
JBrowse link
G Gzmb granzyme B affects expression
multiple interactions
ISO zoledronic acid affects the expression of GZMB mRNA
IL2 protein affects the reaction [zoledronic acid affects the expression of GZMB mRNA]
CTD PMID:19446661 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Zoledronic Acid results in increased expression of H1-2 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO Zoledronic Acid results in increased expression of H2AC18 mRNA CTD PMID:24714768 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Zoledronic Acid results in increased expression of H2AC20 mRNA CTD PMID:24714768 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2ax H2A.X variant histone increases expression ISO Zoledronic Acid results in increased expression of H2AX mRNA CTD PMID:20977926 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO Zoledronic Acid results in increased expression of H2BC12 mRNA CTD PMID:24714768 NCBI chr17:42,485,699...42,486,162 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO zoledronic acid results in decreased expression of HADHA mRNA CTD PMID:28871336 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression ISO zoledronic acid results in increased expression of HAPLN3 mRNA CTD PMID:24714768 NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO zoledronic acid results in increased expression of HAVCR1 mRNA CTD PMID:28871336 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO zoledronic acid results in increased expression of HDAC9 mRNA CTD PMID:24714768 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
JBrowse link
G Hdgf heparin binding growth factor increases expression ISO zoledronic acid results in increased expression of HDGF mRNA CTD PMID:24714768 NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747
JBrowse link
G Heg1 heart development protein with EGF-like domains 1 increases expression ISO zoledronic acid results in increased expression of HEG1 mRNA CTD PMID:24714768 NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051
JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 decreases expression ISO zoledronic acid results in decreased expression of HERC4 mRNA CTD PMID:20977926 NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO zoledronic acid results in decreased expression of HES1 mRNA CTD PMID:24714768 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes2 hes family bHLH transcription factor 2 decreases expression ISO zoledronic acid results in decreased expression of HES2 mRNA CTD PMID:24714768 NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression ISO zoledronic acid results in decreased expression of HGD mRNA CTD PMID:24714768 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hhla2 HHLA2 member of B7 family increases expression ISO zoledronic acid results in increased expression of HHLA2 mRNA CTD PMID:24714768 NCBI chr11:51,257,681...51,271,408 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions EXP zoledronic acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein] CTD PMID:25818600 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hint2 histidine triad nucleotide binding protein 2 increases expression ISO zoledronic acid results in increased expression of HINT2 protein CTD PMID:28871336 NCBI chr 5:57,904,613...57,906,868
Ensembl chr 5:57,904,614...57,907,097
JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO Zoledronic Acid results in increased expression of H2AC6 mRNA CTD PMID:24714768 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Zoledronic Acid results in increased expression of H2BC21 mRNA CTD PMID:24714768 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO Zoledronic Acid results in increased expression of H2BC5 mRNA CTD PMID:24714768 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO zoledronic acid results in decreased expression of HLF mRNA CTD PMID:24714768 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmcn1 hemicentin 1 decreases expression ISO zoledronic acid results in decreased expression of HMCN1 mRNA CTD PMID:24714768 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
JBrowse link
G Hmgb3 high mobility group box 3 increases expression ISO zoledronic acid results in increased expression of HMGB3 mRNA CTD PMID:24714768 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO zoledronic acid results in increased expression of HMGCS1 mRNA CTD PMID:24714768 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO zoledronic acid results in decreased expression of HMMR mRNA CTD PMID:24714768 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of HMOX1 mRNA
Zoledronic Acid results in increased expression of HMOX1 mRNA
CTD PMID:24714768 PMID:25596134 PMID:35587103 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions ISO [Tretinoin co-treated with zoledronic acid] results in increased expression of HMOX2 protein CTD PMID:20349282 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hp1bp3 heterochromatin protein 1, binding protein 3 increases expression ISO zoledronic acid results in increased expression of HP1BP3 mRNA CTD PMID:20977926 NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000
JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression ISO zoledronic acid results in decreased expression of HPCAL4 mRNA CTD PMID:24714768 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression ISO zoledronic acid results in decreased expression of HPGD mRNA CTD PMID:24714768 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases localization
increases expression
ISO zoledronic acid results in decreased localization of HRAS protein
zoledronic acid results in increased expression of HRAS protein
CTD PMID:11986784 PMID:28871336 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 increases expression ISO zoledronic acid results in increased expression of HS3ST1 mRNA CTD PMID:24714768 NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248
JBrowse link
G Hs3st3a1 heparan sulfate-glucosamine 3-sulfotransferase 3A1 increases expression ISO zoledronic acid results in increased expression of HS3ST3A1 mRNA CTD PMID:24714768 NCBI chr10:49,092,850...49,180,676
Ensembl chr10:49,094,026...49,180,676
JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 decreases expression ISO zoledronic acid results in decreased expression of HS3ST3B1 mRNA CTD PMID:20977926 NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression ISO zoledronic acid results in increased expression of HSD11B1 mRNA CTD PMID:24714768 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression ISO zoledronic acid results in decreased expression of HSD11B2 mRNA CTD PMID:24714768 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO zoledronic acid results in increased expression of HSD17B2 mRNA CTD PMID:24714768 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO zoledronic acid results in decreased expression of HSD17B4 mRNA CTD PMID:28871336 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A decreases expression ISO zoledronic acid results in decreased expression of HSPA12A mRNA CTD PMID:24714768 NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO zoledronic acid results in increased expression of HSPA2 protein CTD PMID:28871336 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
decreases expression
ISO zoledronic acid results in increased expression of HSPA5 mRNA
Zoledronic Acid results in decreased expression of HSPA5 mRNA; Zoledronic Acid results in decreased expression of HSPA5 protein
CTD PMID:25596134 PMID:35587103 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Zoledronic Acid results in increased expression of HSPA6 protein CTD PMID:28871336 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression ISO zoledronic acid results in increased expression of HSPB8 mRNA CTD PMID:24714768 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 increases expression ISO zoledronic acid results in increased expression of HTR4 mRNA CTD PMID:20977926 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321
JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression ISO zoledronic acid results in decreased expression of HTRA1 mRNA CTD PMID:24714768 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions
increases expression
ISO [zoledronic acid results in decreased geranoylation of RHOA protein] which results in increased expression of IBSP mRNA; geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA]; zoledronic acid inhibits the reaction [RHOA protein results in decreased expression of IBSP mRNA]; zoledronic acid results in increased expression of and results in decreased degradation of IBSP mRNA
zoledronic acid results in increased expression of IBSP protein
CTD PMID:15324309 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO zoledronic acid results in increased expression of ICAM1 protein CTD PMID:19446661 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icoslg inducible T-cell co-stimulator ligand increases expression ISO zoledronic acid results in increased expression of ICOSLG mRNA CTD PMID:24714768 NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703
JBrowse link
G Id1 inhibitor of DNA binding 1 multiple interactions ISO zoledronic acid promotes the reaction [Gossypol results in decreased expression of ID1 mRNA] CTD PMID:19825521 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO zoledronic acid results in increased expression of ID3 mRNA CTD PMID:24714768 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Id4 inhibitor of DNA binding 4 increases expression ISO zoledronic acid results in increased expression of ID4 mRNA CTD PMID:24714768 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression
increases expression
ISO zoledronic acid results in decreased expression of IDH2 mRNA
zoledronic acid results in increased expression of IDH2 protein
CTD PMID:24714768 PMID:28871336 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO
EXP
zoledronic acid results in increased expression of IDI1 mRNA CTD PMID:18325729 PMID:24714768 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO zoledronic acid results in increased expression of IDO1 mRNA; zoledronic acid results in increased expression of INDO mRNA CTD PMID:24714768 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ier5 immediate early response 5 increases expression ISO zoledronic acid results in increased expression of IER5 mRNA CTD PMID:24714768 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Iffo2 intermediate filament family orphan 2 increases expression ISO zoledronic acid results in increased expression of IFFO2 mRNA CTD PMID:24714768 NCBI chr 5:151,830,900...151,876,948
Ensembl chr 5:151,830,701...151,925,345
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO zoledronic acid results in increased expression of IFI27 mRNA CTD PMID:24714768 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO zoledronic acid promotes the reaction [IL2 protein affects the expression of IFNG protein]
zoledronic acid results in increased expression of IFNG protein
CTD PMID:19400555 PMID:19818098 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO zoledronic acid results in increased expression of IFNGR1 mRNA CTD PMID:24714768 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ift81 intraflagellar transport 81 decreases expression ISO zoledronic acid results in decreased expression of IFT81 mRNA CTD PMID:20977926 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of IGF1 mRNA CTD PMID:16996129 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of IGFBP5 mRNA CTD PMID:16996129 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO zoledronic acid results in increased expression of IKBKE mRNA CTD PMID:24714768 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Ikzf5 IKAROS family zinc finger 5 decreases expression ISO zoledronic acid results in decreased expression of IKZF5 mRNA CTD PMID:20977926 NCBI chr 1:186,169,108...186,188,847
Ensembl chr 1:186,170,788...186,188,834
JBrowse link
G Il10 interleukin 10 decreases expression ISO zoledronic acid results in decreased expression of IL10 protein CTD PMID:19818098 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of IL10RA mRNA CTD PMID:16996129 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO zoledronic acid results in increased expression of IL13RA2 mRNA CTD PMID:24714768 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il17rb interleukin 17 receptor B decreases expression ISO zoledronic acid results in decreased expression of IL17RB mRNA CTD PMID:24714768 PMID:25596134 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
JBrowse link
G Il18r1 interleukin 18 receptor 1 increases expression ISO zoledronic acid results in increased expression of IL18R1 mRNA CTD PMID:24714768 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Il19 interleukin 19 increases expression
increases secretion
ISO zoledronic acid results in increased expression of IL19 mRNA
zoledronic acid results in increased secretion of IL19 protein
CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il1b interleukin 1 beta increases expression ISO zoledronic acid results in increased expression of IL1B mRNA CTD PMID:24714768 PMID:28871336 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO zoledronic acid results in increased expression of IL1R1 mRNA CTD PMID:24714768 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression ISO zoledronic acid results in decreased expression of IL1R2 mRNA CTD PMID:24714768 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il2 interleukin 2 multiple interactions ISO IL2 protein affects the reaction [zoledronic acid affects the expression of GZMB mRNA]; zoledronic acid promotes the reaction [IL2 protein affects the expression of IFNG protein] CTD PMID:19400555 PMID:19446661 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO zoledronic acid results in increased expression of IL23A mRNA CTD PMID:20977926 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of IL2RG mRNA CTD PMID:16996129 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Zoledronic Acid results in increased expression of IL36G mRNA CTD PMID:24714768 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO zoledronic acid results in increased expression of IL4I1 mRNA CTD PMID:24714768 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
multiple interactions
ISO Zoledronic Acid results in decreased expression of IL6 mRNA; Zoledronic Acid results in decreased expression of IL6 protein
zoledronic acid results in increased expression of IL6 mRNA; zoledronic acid results in increased expression of IL6 protein
SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of IL6 mRNA]
CTD PMID:9351880 PMID:18601766 PMID:28871336 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 decreases expression ISO zoledronic acid results in decreased expression of IL7 mRNA CTD PMID:24714768 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO zoledronic acid results in increased expression of INHBE mRNA CTD PMID:20977926 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO zoledronic acid results in increased expression of INSIG1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Iqcd IQ motif containing D increases expression ISO zoledronic acid results in increased expression of IQCD mRNA CTD PMID:24714768 NCBI chr12:35,955,522...35,972,420
Ensembl chr12:35,934,716...35,972,523
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO zoledronic acid results in increased expression of IRAK2 mRNA CTD PMID:24714768 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO zoledronic acid results in increased expression of IREB2 mRNA CTD PMID:20977926 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irf2 interferon regulatory factor 2 increases expression ISO zoledronic acid results in increased expression of IRF2 mRNA CTD PMID:24714768 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 decreases expression ISO zoledronic acid results in decreased expression of IRF2BP1 mRNA CTD PMID:20977926 NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530
JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like decreases expression ISO zoledronic acid results in decreased expression of IRF2BPL mRNA CTD PMID:24714768 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
JBrowse link
G Irf8 interferon regulatory factor 8 decreases expression ISO zoledronic acid results in decreased expression of IRF8 mRNA CTD PMID:24714768 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irx3 iroquois homeobox 3 decreases expression ISO zoledronic acid results in decreased expression of IRX3 mRNA CTD PMID:24714768 NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317
JBrowse link
G Ism1 isthmin 1 increases expression ISO zoledronic acid results in increased expression of ISM1 mRNA CTD PMID:24714768 NCBI chr 3:127,023,296...127,102,228
Ensembl chr 3:127,021,865...127,101,894
JBrowse link
G Ism2 isthmin 2 decreases expression ISO zoledronic acid results in decreased expression of ISM2 mRNA CTD PMID:24714768 NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 decreases expression ISO zoledronic acid results in decreased expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
JBrowse link
G Itga1 integrin subunit alpha 1 increases expression ISO zoledronic acid results in increased expression of ITGA1 mRNA CTD PMID:24714768 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression ISO zoledronic acid results in increased expression of ITGB2 mRNA CTD PMID:24714768 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO zoledronic acid results in decreased expression of ITGB5 mRNA CTD PMID:24714768 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression ISO zoledronic acid results in increased expression of ITIH3 protein CTD PMID:28871336 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itprid2 ITPR interacting domain containing 2 decreases expression ISO zoledronic acid results in decreased expression of ITPRID2 mRNA CTD PMID:24714768 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
JBrowse link
G Ivns1abp influenza virus NS1A binding protein decreases expression ISO zoledronic acid results in decreased expression of IVNS1ABP mRNA CTD PMID:24714768 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Iyd iodotyrosine deiodinase decreases expression ISO zoledronic acid results in decreased expression of IYD mRNA CTD PMID:24714768 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Izumo4 IZUMO family member 4 increases expression ISO zoledronic acid results in increased expression of IZUMO4 mRNA CTD PMID:24714768 NCBI chr 7:9,007,276...9,010,428
Ensembl chr 7:9,007,280...9,010,032
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO zoledronic acid results in increased expression of JAK1 mRNA CTD PMID:24714768 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 increases expression ISO zoledronic acid results in increased expression of JAK2 mRNA CTD PMID:24714768 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jak3 Janus kinase 3 increases expression ISO zoledronic acid results in increased expression of JAK3 mRNA CTD PMID:20977926 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Josd1 Josephin domain containing 1 increases expression ISO zoledronic acid results in increased expression of JOSD1 mRNA CTD PMID:20977926 NCBI chr 7:111,230,318...111,244,241
Ensembl chr 7:111,230,318...111,244,652
JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO [zoledronic acid co-treated with fluvastatin] results in increased expression of KAT2B mRNA CTD PMID:16996129 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 increases expression ISO zoledronic acid results in increased expression of KBTBD2 mRNA CTD PMID:20977926 NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 decreases expression ISO zoledronic acid results in decreased expression of KCNH1 mRNA CTD PMID:24714768 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
JBrowse link
G Kcnh3 potassium voltage-gated channel subfamily H member 3 decreases expression ISO zoledronic acid results in decreased expression of KCNH3 mRNA CTD PMID:24714768 NCBI chr 7:130,365,593...130,383,859
Ensembl chr 7:130,366,011...130,383,855
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 increases expression ISO zoledronic acid results in increased expression of KCNIP3 mRNA CTD PMID:24714768 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
JBrowse link
G Kcnip4 potassium voltage-gated channel interacting protein 4 decreases expression ISO zoledronic acid results in decreased expression of KCNIP4 mRNA CTD PMID:24714768 NCBI chr14:61,380,699...62,531,399
Ensembl chr14:61,381,076...62,530,144
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 decreases expression ISO zoledronic acid results in decreased expression of KCNJ1 mRNA CTD PMID:24714768 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcns3 potassium voltage-gated channel, modifier subfamily S, member 3 increases expression ISO zoledronic acid results in increased expression of KCNS3 mRNA CTD PMID:24714768 NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression ISO zoledronic acid results in increased expression of KCTD5 mRNA CTD PMID:20977926 NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO zoledronic acid results in increased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Kiaa0930 KIAA0930 homolog decreases expression ISO zoledronic acid results in decreased expression of KIAA0930 mRNA CTD PMID:24714768 NCBI chr 7:116,067,974...116,107,678
Ensembl chr 7:116,071,447...116,107,727
JBrowse link
G Kif13a kinesin family member 13A decreases expression ISO zoledronic acid results in decreased expression of KIF13A protein CTD PMID:28871336 NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO zoledronic acid results in decreased expression of KIF20A mRNA CTD PMID:20977926 PMID:24714768 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO zoledronic acid results in decreased expression of KIF4A mRNA CTD PMID:24714768 NCBI chr  X:65,721,746...65,824,277
Ensembl chr  X:65,721,779...65,824,139
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO zoledronic acid results in decreased expression of KIFC1 mRNA CTD PMID:24714768 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO zoledronic acid results in increased expression of KIT mRNA CTD PMID:24714768 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kitlg KIT ligand decreases expression ISO zoledronic acid results in decreased expression of KITLG mRNA CTD PMID:24714768 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf11 KLF transcription factor 11 increases expression ISO zoledronic acid results in increased expression of KLF11 mRNA CTD PMID:20977926 PMID:24714768 NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO Zoledronic Acid results in increased expression of KLF7 mRNA CTD PMID:20977926 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Klhl13 kelch-like family member 13 decreases expression ISO zoledronic acid results in decreased expression of KLHL13 mRNA CTD PMID:24714768 NCBI chr  X:113,942,309...114,107,299
Ensembl chr  X:113,942,309...114,107,321
JBrowse link
G Klk10 kallikrein related-peptidase 10 increases expression ISO zoledronic acid results in increased expression of KLK10 mRNA CTD PMID:24714768 NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376
JBrowse link
G Klk6 kallikrein related-peptidase 6 decreases expression ISO zoledronic acid results in decreased expression of KLK6 mRNA CTD PMID:24714768 NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
JBrowse link
G Klrg2 killer cell lectin like receptor G2 increases expression ISO zoledronic acid results in increased expression of KLRG2 mRNA CTD PMID:24714768 NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression ISO zoledronic acid results in increased expression of KRAS protein CTD PMID:28871336 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krcc1 lysine-rich coiled-coil 1 increases expression ISO zoledronic acid results in increased expression of KRCC1 mRNA CTD PMID:20977926 NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156
JBrowse link
G Krt15 keratin 15 increases expression ISO zoledronic acid results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt8 keratin 8 decreases expression ISO zoledronic acid results in decreased expression of KRT8 mRNA CTD PMID:24714768 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Krt80 keratin 80 decreases expression ISO zoledronic acid results in decreased expression of KRT80 mRNA CTD PMID:24714768 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Krt81 keratin 81 decreases expression ISO zoledronic acid results in decreased expression of KRT81 mRNA CTD PMID:24714768 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
JBrowse link
G Kynu kynureninase increases expression ISO zoledronic acid results in increased expression of KYNU mRNA CTD PMID:24714768 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G L3mbtl3 L3MBTL histone methyl-lysine binding protein 3 decreases expression ISO zoledronic acid results in decreased expression of L3MBTL3 mRNA CTD PMID:24714768 NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263
JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression ISO zoledronic acid results in decreased expression of LAMA1 mRNA CTD PMID:24714768 PMID:25596134 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO zoledronic acid results in increased expression of LAMA3 mRNA CTD PMID:20977926 PMID:24714768 PMID:25596134 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
JBrowse link
G Lama4 laminin subunit alpha 4 decreases expression ISO zoledronic acid results in decreased expression of LAMA4 mRNA CTD PMID:24714768 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions ISO [zoledronic acid co-treated with Gossypol] results in decreased expression of LAMA5 mRNA CTD PMID:19825521 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO zoledronic acid results in decreased expression of LAMB1 mRNA CTD PMID:24714768 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO zoledronic acid results in increased expression of LAMB3 mRNA CTD PMID:24714768 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO zoledronic acid results in increased expression of LAMC2 mRNA CTD PMID:24714768 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 decreases expression ISO zoledronic acid results in decreased expression of LAMP1 protein CTD PMID:28871336 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO zoledronic acid results in increased expression of LBH mRNA CTD PMID:24714768 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
JBrowse link
G Lcn2 lipocalin 2 increases expression
increases secretion
ISO zoledronic acid results in increased expression of LCN2 mRNA
zoledronic acid results in increased secretion of LCN2 protein
CTD PMID:24714768 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression ISO zoledronic acid results in increased expression of LCP1 mRNA CTD PMID:24714768 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Ldaf1 lipid droplet assembly factor 1 increases expression ISO Zoledronic Acid results in increased expression of LDAF1 mRNA CTD PMID:24714768 NCBI chr 1:174,484,438...174,503,037
Ensembl chr 1:174,484,447...174,503,036
JBrowse link
G Ldb2 LIM domain binding 2 increases expression ISO zoledronic acid results in increased expression of LDB2 mRNA CTD PMID:24714768 NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO zoledronic acid results in increased expression of LDLR mRNA CTD PMID:20977926 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldoc1 LDOC1, regulator of NFKB signaling decreases expression ISO zoledronic acid results in decreased expression of LDOC1 mRNA CTD PMID:24714768 NCBI chr  X:139,965,509...140,074,355
Ensembl chr  X:139,965,509...140,074,355
JBrowse link
G Leg1 liver enriched gene 1 increases expression ISO zoledronic acid results in increased expression of C6ORF58 mRNA CTD PMID:24714768 NCBI chr 1:28,799,902...28,816,230
Ensembl chr 1:28,799,902...28,815,993
JBrowse link
G Lgi2 leucine-rich repeat LGI family, member 2 decreases expression ISO zoledronic acid results in decreased expression of LGI2 mRNA CTD PMID:24714768 NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407