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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-fluorouracil
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Accession:CHEBI:46345 term browser browse the term
Definition:A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Synonyms:exact_synonym: 5-fluoropyrimidine-2,4(1H,3H)-dione
 related_synonym: 5-FU;   5-Fluoracil;   5-Fluoropyrimidine-2,4-dione;   Formula=C4H3FN2O2;   InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9);   InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N;   SMILES=Fc1c[nH]c(=O)[nH]c1=O;   fluorouracil;   fluorouracilo;   fluorouracilum
 alt_id: CHEBI:2054;   CHEBI:46343
 xref: Beilstein:127172;   CAS:51-21-8;   DrugBank:DB00544;   Drug_Central:26;   HMDB:HMDB0014684;   KEGG:C07649;   KEGG:D00584;   LINCS:LSM-4261
 xref_mesh: MESH:D005472
 xref: PDBeChem:URF;   PMID:11356943;   PMID:12520460;   PMID:14769231;   PMID:19023200;   Reaxys:127172;   Wikipedia:Fluorouracil


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5-fluorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS1 mRNA] CTD PMID:15016801 NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
increases expression
decreases expression		 EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil; ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
Fluorouracil results in increased expression of ABCB1 protein
Fluorouracil results in decreased expression of ABCB1 mRNA		 CTD PMID:12576456 PMID:15239124 PMID:17287894 PMID:21332314 PMID:21833476 More... NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) decreases expression
decreases response to substance		 EXP Fluorouracil results in decreased expression of ABCB6 mRNA
ABCB6 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:20737486 PMID:25202056 NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) multiple interactions EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:32800223 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC11 ATP binding cassette subfamily C member 11 decreases response to substance EXP ABCC11 protein results in decreased susceptibility to Fluorouracil CTD PMID:18310281 NCBI chr16:48,164,819...48,247,539
Ensembl chr16:48,165,773...48,247,568 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 affects response to substance
multiple interactions		 EXP ABCC2 protein affects the susceptibility to Fluorouracil
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA		 CTD PMID:16217747 PMID:32800223 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 decreases response to substance
multiple interactions		 EXP ABCC5 protein results in decreased susceptibility to Fluorouracil
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Fluorouracil]; ABCC5 protein results in increased export of and results in decreased susceptibility to Fluorouracil		 CTD PMID:15897250 PMID:19077464 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 affects response to substance
increases expression		 EXP ABCC6 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of ABCC6 protein		 CTD PMID:15352031 NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:21712253 PMID:21833476 PMID:32800223 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABHD12B abhydrolase domain containing 12B decreases expression EXP Fluorouracil results in decreased expression of ABHD12B mRNA CTD PMID:24737281 NCBI chr14:50,872,053...50,904,970
Ensembl chr14:50,872,053...50,904,970 		JBrowse link
G ABI1 abl interactor 1 increases expression ISO Fluorouracil results in increased expression of ABI1 mRNA CTD PMID:19272435 NCBI chr10:26,746,596...26,860,958
Ensembl chr10:26,746,593...26,861,087 		JBrowse link
G ABI2 abl interactor 2 decreases expression ISO Fluorouracil results in decreased expression of ABI2 mRNA CTD PMID:19272435 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728 		JBrowse link
G ACAD9 acyl-CoA dehydrogenase family member 9 decreases expression EXP Fluorouracil results in decreased expression of ACAD9 mRNA CTD PMID:34151400 NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain increases expression EXP Fluorouracil results in increased expression of ACADL protein CTD PMID:15585135 PMID:16803524 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACKR3 atypical chemokine receptor 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA] CTD PMID:15016801 NCBI chr 2:236,537,122...236,582,354
Ensembl chr 2:236,567,787...236,582,354 		JBrowse link
G ACOT13 acyl-CoA thioesterase 13 affects response to substance EXP ACOT13 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:24,667,077...24,705,046
Ensembl chr 6:24,667,035...24,705,065 		JBrowse link
G ACOT7 acyl-CoA thioesterase 7 affects response to substance EXP ACOT7 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767 		JBrowse link
G ACSM3 acyl-CoA synthetase medium chain family member 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA] CTD PMID:15016801 NCBI chr16:20,674,405...20,797,581
Ensembl chr16:20,610,243...20,797,581 		JBrowse link
G ACTB actin beta decreases expression ISO Fluorouracil results in decreased expression of ACTB protein CTD PMID:21296659 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ACTC1 actin alpha cardiac muscle 1 decreases expression ISO Fluorouracil results in decreased expression of ACTC1 protein CTD PMID:21296659 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589 		JBrowse link
G ACTG2 actin gamma 2, smooth muscle decreases expression EXP Fluorouracil results in decreased expression of ACTG2 mRNA CTD PMID:16709241 NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865 		JBrowse link
G ACTL8 actin like 8 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACTL8 mRNA] CTD PMID:15016801 NCBI chr 1:17,755,333...17,827,063
Ensembl chr 1:17,755,333...17,827,063 		JBrowse link
G ACY1 aminoacylase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA] CTD PMID:15016801 NCBI chr 3:51,983,535...51,989,197
Ensembl chr 3:51,983,340...51,989,197 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA] CTD PMID:15016801 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAM3A ADAM metallopeptidase domain 3A (pseudogene) multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA] CTD PMID:15016801 NCBI chr 8:39,451,045...39,522,989
Ensembl chr 8:39,451,045...39,522,852
Ensembl chr 8:39,451,045...39,522,852 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA] CTD PMID:15016801 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADCY9 adenylate cyclase 9 decreases expression EXP Fluorouracil results in decreased expression of ADCY9 mRNA CTD PMID:19219653 NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442 		JBrowse link
G ADD3 adducin 3 affects response to substance EXP ADD3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 affects response to substance EXP ADGRG1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:57,619,738...57,665,567
Ensembl chr16:57,610,652...57,665,580 		JBrowse link
G ADGRG6 adhesion G protein-coupled receptor G6 affects response to substance EXP ADGRG6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:142,302,007...142,446,261
Ensembl chr 6:142,301,854...142,446,266 		JBrowse link
G ADGRL2 adhesion G protein-coupled receptor L2 affects response to substance EXP ADGRL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:81,306,132...81,993,932
Ensembl chr 1:81,306,147...81,993,932 		JBrowse link
G ADIRF adipogenesis regulatory factor increases expression EXP Fluorouracil results in increased expression of ADIRF mRNA CTD PMID:17039268 NCBI chr10:86,968,482...86,970,915
Ensembl chr10:86,968,432...87,007,922 		JBrowse link
G ADM adrenomedullin affects response to substance EXP ADM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADSS2 adenylosuccinate synthase 2 decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of ADSS2 mRNA
Fluorouracil results in increased expression of ADSS2 protein		 CTD PMID:15585135 PMID:16709241 PMID:16803524 NCBI chr 1:244,408,494...244,452,060
Ensembl chr 1:244,408,494...244,451,909 		JBrowse link
G AFP alpha fetoprotein increases expression
decreases expression		 ISO Fluorouracil results in increased expression of AFP protein
Fluorouracil results in decreased expression of AFP; Fluorouracil results in decreased expression of AFP mRNA		 CTD PMID:20448262 PMID:21296659 PMID:26272751 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 decreases expression EXP Fluorouracil results in decreased expression of AGAP3 mRNA CTD PMID:16709241 NCBI chr 7:151,085,867...151,144,434
Ensembl chr 7:151,085,831...151,144,436 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA] CTD PMID:15016801 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AHNAK AHNAK nucleoprotein decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of AHNAK protein
AHNAK protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions
increases expression		 EXP
ISO		 [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased expression of AIFM1 protein
Fluorouracil results in increased expression of AIFM1 protein
[Fluorouracil co-treated with casticin] results in increased expression of AIFM1 protein		 CTD PMID:16168113 PMID:32270916 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G AKAP12 A-kinase anchoring protein 12 affects expression EXP Fluorouracil affects the expression of AKAP12 mRNA CTD PMID:16584549 NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 affects expression EXP Fluorouracil affects the expression of AKR1B10 mRNA CTD PMID:16584549 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412 		JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 affects response to substance
affects expression		 EXP AKR1C1 protein affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of AKR1C1 mRNA		 CTD PMID:16217747 PMID:16584549 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 affects response to substance EXP AKR1C2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 affects expression
affects response to substance		 EXP Fluorouracil affects the expression of AKR1C3 mRNA
AKR1C3 protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16584549 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
affects expression
decreases phosphorylation
affects phosphorylation
increases phosphorylation		 EXP
ISO		 [Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein; AG 1879 inhibits the reaction [Fluorouracil results in increased phosphorylation of AKT1 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Nicotine affects the reaction [Fluorouracil affects the phosphorylation of AKT1 protein]
Fluorouracil affects the expression of AKT1 mRNA
Fluorouracil results in decreased phosphorylation of AKT1 protein
Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]		 CTD PMID:16724238 PMID:17918158 PMID:18794807 PMID:19885610 PMID:24095863 More... NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 increases expression EXP Fluorouracil results in increased expression of AKT2 protein CTD PMID:16803524 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G ALB albumin multiple interactions EXP [Leucovorin co-treated with Cisplatin co-treated with Fluorouracil] results in decreased expression of ALB protein CTD PMID:20180123 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALCAM activated leukocyte cell adhesion molecule affects response to substance
decreases expression		 EXP ALCAM protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALCAM protein		 CTD PMID:15352031 NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 affects response to substance EXP ALDH1A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 affects response to substance
decreases expression		 EXP ALDH1A3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALDH1A3 protein		 CTD PMID:15352031 NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626 		JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 affects response to substance EXP ALDH3A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760 		JBrowse link
G ALG3 ALG3 alpha-1,3- mannosyltransferase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA] CTD PMID:15016801 NCBI chr 3:184,242,301...184,249,525
Ensembl chr 3:184,242,301...184,249,548 		JBrowse link
G ALKBH8 alkB homolog 8, tRNA methyltransferase decreases expression EXP Fluorouracil results in decreased expression of ALKBH8 mRNA CTD PMID:16510598 NCBI chr11:107,502,727...107,565,735
Ensembl chr11:107,502,727...107,565,742 		JBrowse link
G AMFR autocrine motility factor receptor multiple interactions EXP AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr16:56,361,452...56,425,545
Ensembl chr16:56,361,452...56,425,545 		JBrowse link
G AMPD2 adenosine monophosphate deaminase 2 decreases expression EXP Fluorouracil results in decreased expression of AMPD2 mRNA CTD PMID:19219653 NCBI chr 1:109,619,837...109,632,055
Ensembl chr 1:109,616,104...109,632,051 		JBrowse link
G AMT aminomethyltransferase increases expression EXP Fluorouracil results in increased expression of AMT protein CTD PMID:15585135 PMID:16803524 NCBI chr 3:49,416,778...49,422,473
Ensembl chr 3:49,416,778...49,422,685 		JBrowse link
G ANG angiogenin affects response to substance EXP ANG protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANGPT1 angiopoietin 1 multiple interactions
increases expression		 EXP ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein]
Fluorouracil results in increased expression of ANGPT1 protein		 CTD PMID:17786339 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ANGPT2 angiopoietin 2 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of ANGPT2 protein
ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]		 CTD PMID:17786339 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ANGPTL2 angiopoietin like 2 multiple interactions EXP ANGPTL2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635 		JBrowse link
G ANGPTL3 angiopoietin like 3 decreases expression EXP Fluorouracil results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313 		JBrowse link
G ANGPTL4 angiopoietin like 4 affects response to substance EXP ANGPTL4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370 		JBrowse link
G ANKRD1 ankyrin repeat domain 1 increases expression EXP Fluorouracil results in increased expression of ANKRD1 mRNA CTD PMID:17039268 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087 		JBrowse link
G ANKRD11 ankyrin repeat domain containing 11 increases expression
affects expression		 EXP Fluorouracil results in increased expression of ANKRD11 mRNA
Fluorouracil affects the expression of ANKRD11 mRNA		 CTD PMID:16510598 PMID:16584549 NCBI chr16:89,267,630...89,490,561
Ensembl chr16:89,267,619...89,490,561 		JBrowse link
G ANKRD13C-DT ANKRD13C divergent transcript affects expression EXP Fluorouracil affects the expression of ANKRD13C-DT mRNA CTD PMID:16584549 NCBI chr 1:70,354,811...70,368,023
Ensembl chr 1:70,354,780...70,385,339 		JBrowse link
G ANKRD36 ankyrin repeat domain 36 increases expression EXP Fluorouracil results in increased expression of ANKRD36 mRNA CTD PMID:16510598 NCBI chr 2:97,113,153...97,264,521
Ensembl chr 2:97,113,153...97,264,521 		JBrowse link
G ANKRD36B ankyrin repeat domain 36B affects expression EXP Fluorouracil affects the expression of ANKRD36B mRNA CTD PMID:16584549 NCBI chr 2:97,492,663...97,589,877
Ensembl chr 2:97,492,663...97,589,877 		JBrowse link
G ANLN anillin, actin binding protein multiple interactions
decreases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA] CTD PMID:15016801 PMID:17982676 NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791 		JBrowse link
G ANP32E acidic nuclear phosphoprotein 32 family member E multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA] CTD PMID:15016801 NCBI chr 1:150,218,417...150,236,112
Ensembl chr 1:150,218,417...150,236,156 		JBrowse link
G ANXA1 annexin A1 affects response to substance
decreases expression		 EXP ANXA1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ANXA1 protein		 CTD PMID:15352031 PMID:16217747 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G ANXA2 annexin A2 decreases response to substance
multiple interactions
increases expression		 EXP ANXA2 mRNA results in decreased susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA]		 CTD PMID:15152939 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA3 annexin A3 increases expression EXP Fluorouracil results in increased expression of ANXA3 mRNA CTD PMID:17039268 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451 		JBrowse link
G ANXA4 annexin A4 decreases expression EXP Fluorouracil results in decreased expression of ANXA4 mRNA CTD PMID:15109396 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112 		JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of AP2S1 mRNA CTD PMID:16391804 NCBI chr19:46,838,167...46,850,846
Ensembl chr19:46,838,136...46,850,846 		JBrowse link
G AP3S1 adaptor related protein complex 3 subunit sigma 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA] CTD PMID:15016801 NCBI chr 5:115,841,935...115,914,081
Ensembl chr 5:115,841,592...115,914,081 		JBrowse link
G AP4S1 adaptor related protein complex 4 subunit sigma 1 decreases expression EXP Fluorouracil results in decreased expression of AP4S1 mRNA CTD PMID:16510598 NCBI chr14:31,025,106...31,096,450
Ensembl chr14:31,025,106...31,130,996 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression
affects expression		 EXP Fluorouracil results in increased expression of APAF1 mRNA
Fluorouracil affects the expression of APAF1 mRNA		 CTD PMID:16557594 PMID:34151400 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G APBA2 amyloid beta precursor protein binding family A member 2 affects response to substance EXP APBA2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:28,885,974...29,118,315
Ensembl chr15:28,884,483...29,118,315 		JBrowse link
G APBB2 amyloid beta precursor protein binding family B member 2 affects response to substance EXP APBB2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:40,810,027...41,214,542
Ensembl chr 4:40,810,027...41,216,714 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance EXP APEX1 protein mutant form results in increased susceptibility to Fluorouracil CTD PMID:19470598 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APOB apolipoprotein B decreases expression
decreases secretion
multiple interactions		 EXP Fluorouracil results in decreased expression of APOB mRNA
Fluorouracil results in decreased secretion of APOB protein
ursodoxicoltaurine inhibits the reaction [Fluorouracil results in decreased expression of APOB mRNA]		 CTD PMID:32535746 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C decreases expression
increases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of APOBEC3C protein
Fluorouracil results in increased expression of APOBEC3C mRNA
APOBEC3C protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16510598 NCBI chr22:39,014,257...39,020,352
Ensembl chr22:39,014,257...39,020,352 		JBrowse link
G APOC1 apolipoprotein C1 affects response to substance EXP APOC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC3 apolipoprotein C3 decreases secretion
decreases expression		 EXP Fluorouracil results in decreased secretion of APOC3 protein
Fluorouracil results in decreased expression of APOC3 mRNA		 CTD PMID:32535746 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G AQP12B aquaporin 12B decreases expression EXP Fluorouracil results in decreased expression of AQP12B mRNA CTD PMID:34151400 NCBI chr 2:240,676,418...240,683,810
Ensembl chr 2:240,676,418...240,682,906 		JBrowse link
G AQP6 aquaporin 6 decreases expression EXP Fluorouracil results in decreased expression of AQP6 mRNA CTD PMID:34151400 NCBI chr12:49,972,947...49,977,139
Ensembl chr12:49,967,194...49,977,139 		JBrowse link
G AQP9 aquaporin 9 increases uptake ISO AQP9 protein results in increased uptake of Fluorouracil CTD PMID:9733774 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911 		JBrowse link
G AREG amphiregulin affects response to substance
increases expression		 EXP AREG affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of AREG mRNA		 CTD PMID:15067352 PMID:16709241 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARF1 ARF GTPase 1 multiple interactions EXP ARF1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,708...228,099,212 		JBrowse link
G ARF3 ARF GTPase 3 affects response to substance EXP ARF3 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr12:48,935,723...48,957,487
Ensembl chr12:48,935,723...48,957,487 		JBrowse link
G ARFGAP1 ARF GTPase activating protein 1 increases expression EXP Fluorouracil results in increased expression of ARFGAP1 protein CTD PMID:15331170 NCBI chr20:63,272,813...63,289,790
Ensembl chr20:63,272,785...63,289,790 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta affects expression EXP Fluorouracil affects the expression of ARHGDIB mRNA CTD PMID:34151400 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728 		JBrowse link
G ARID5B AT-rich interaction domain 5B affects response to substance EXP ARID5B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944 		JBrowse link
G ARL4C ARF like GTPase 4C increases expression EXP Fluorouracil results in increased expression of ARL4C mRNA CTD PMID:16510598 NCBI chr 2:234,493,041...234,497,081
Ensembl chr 2:234,493,041...234,497,081 		JBrowse link
G ARL6IP5 ARF like GTPase 6 interacting protein 5 multiple interactions EXP ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin] CTD PMID:22452940 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092 		JBrowse link
G ARMCX1 armadillo repeat containing X-linked 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA] CTD PMID:15016801 NCBI chr  X:101,550,547...101,554,700
Ensembl chr  X:101,550,547...101,554,700 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 decreases expression EXP Fluorouracil results in decreased expression of ARPC3 mRNA CTD PMID:16709241 NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 affects response to substance
multiple interactions		 EXP ASAH1 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ASS1 argininosuccinate synthase 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of ASS1 mRNA CTD PMID:16391804 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G ATF3 activating transcription factor 3 affects expression
multiple interactions
increases expression		 EXP Fluorouracil affects the expression of ATF3 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA]
Fluorouracil results in increased expression of ATF3 mRNA; Fluorouracil results in increased expression of ATF3 protein		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:16709241 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATF4 activating transcription factor 4 increases expression EXP Fluorouracil results in increased expression of ATF4 protein CTD PMID:29879413 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686 		JBrowse link
G ATF6 activating transcription factor 6 affects expression EXP Fluorouracil affects the expression of ATF6 mRNA CTD PMID:34151400 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATG12 autophagy related 12 decreases expression EXP Fluorouracil results in decreased expression of ATG12 mRNA CTD PMID:16510598 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATM ATM serine/threonine kinase decreases response to substance EXP ATM protein results in decreased susceptibility to Fluorouracil CTD PMID:35608750 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 affects expression EXP Fluorouracil affects the expression of ATOH8 mRNA CTD PMID:16584549 NCBI chr 2:85,753,991...85,791,383
Ensembl chr 2:85,751,344...85,791,383 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta multiple interactions
affects expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA]
Fluorouracil affects the expression of ATP5F1D mRNA		 CTD PMID:15016801 PMID:34151400 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b affects expression EXP Fluorouracil affects the expression of ATP5PB mRNA CTD PMID:34151400 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773 		JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 increases expression EXP Fluorouracil results in increased expression of ATP5PF mRNA CTD PMID:34151400 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP multiple interactions EXP ATP5PO mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814 		JBrowse link
G ATP7B ATPase copper transporting beta increases response to substance EXP ATP7B mRNA results in increased susceptibility to Fluorouracil CTD PMID:18593893 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G ATP9A ATPase phospholipid transporting 9A (putative) decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of ATP9A protein
ATP9A protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr20:51,596,514...51,768,390
Ensembl chr20:51,596,514...51,768,390 		JBrowse link
G ATXN10 ataxin 10 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA] CTD PMID:15016801 NCBI chr22:45,671,834...45,845,307
Ensembl chr22:45,671,798...45,845,307 		JBrowse link
G AURKA aurora kinase A decreases expression EXP
ISO		 Fluorouracil results in decreased expression of AURKA mRNA CTD PMID:15205334 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G AVEN apoptosis and caspase activation inhibitor decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of AVEN mRNA
Fluorouracil results in increased expression of AVEN mRNA		 CTD PMID:16510598 PMID:16709241 NCBI chr15:33,851,781...34,075,325
Ensembl chr15:33,858,782...34,075,155 		JBrowse link
G AXIN1 axin 1 multiple interactions ISO 5-fluorouracil inhibits the reaction [N-methyl-N-nitrosourea decreases expression of Axin1 mRNA in colon] RGD PMID:28032729 RGD:150530464 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA] CTD PMID:31129132 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAG3 BAG cochaperone 3 affects response to substance EXP BAG3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases expression
multiple interactions
increases response to substance		 EXP Fluorouracil results in increased expression of BAK1; Fluorouracil results in increased expression of BAK1 mRNA; Fluorouracil results in increased expression of BAK1 protein
mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BAK1 protein]
BAK1 mRNA results in increased susceptibility to Fluorouracil		 CTD PMID:9792140 PMID:15489892 PMID:16557594 PMID:18593893 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G BARX2 BARX homeobox 2 increases expression EXP Fluorouracil results in increased expression of BARX2 protein CTD PMID:15585135 PMID:16803524 NCBI chr11:129,375,233...129,452,279
Ensembl chr11:129,375,848...129,452,279 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
decreases expression
increases response to substance		 EXP
ISO		 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in increased expression of BAX mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of BAX protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of BAX protein; [wogonin co-treated with Fluorouracil] results in increased expression of BAX protein; Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BAX mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BAX mRNA]; Fluorouracil affects the reaction [rebamipide results in decreased expression of BAX protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of BAX protein]; Fluorouracil promotes the reaction [andrographolide affects the folding of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]; Fluorouracil promotes the reaction [Plant Extracts results in increased expression of BAX protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]
Fluorouracil results in increased expression of BAX; Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein
[Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein; casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein]
Fluorouracil results in decreased expression of BAX mRNA; Fluorouracil results in decreased expression of BAX protein
BAX protein results in increased susceptibility to Fluorouracil		 CTD PMID:9388485 PMID:9792140 PMID:11062132 PMID:11750847 PMID:12442003 More... NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 increases response to substance
increases expression
multiple interactions		 EXP BBC3 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of BBC3 mRNA; Fluorouracil results in increased expression of BBC3 protein
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]		 CTD PMID:14665630 PMID:15016801 PMID:15489892 PMID:16481741 PMID:16557594 More... NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BBS4 Bardet-Biedl syndrome 4 multiple interactions EXP BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr15:72,686,207...72,738,473
Ensembl chr15:72,686,186...72,742,006 		JBrowse link
G BBX BBX high mobility group box domain containing affects response to substance EXP BBX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:107,522,962...107,811,339
Ensembl chr 3:107,522,936...107,811,339 		JBrowse link
G BCAR3 BCAR3 adaptor protein, NSP family member affects response to substance
decreases expression		 EXP BCAR3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BCAR3 protein		 CTD PMID:15352031 NCBI chr 1:93,561,741...93,848,151
Ensembl chr 1:93,561,741...93,847,150 		JBrowse link
G BCAS4 breast carcinoma amplified sequence 4 affects response to substance EXP BCAS4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:50,794,894...50,882,676
Ensembl chr20:50,794,894...50,877,177 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA] CTD PMID:15016801 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha affects expression EXP Fluorouracil affects the expression of BCKDHA mRNA CTD PMID:16584549 NCBI chr19:41,397,818...41,425,002
Ensembl chr19:41,397,808...41,425,002 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
affects expression
affects response to substance
decreases expression
increases expression
increases phosphorylation
decreases response to substance		 EXP
ISO		 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 protein; [wogonin co-treated with Fluorouracil] results in decreased expression of BCL2 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BCL2 protein]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BCL2 mRNA]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]
BCL2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of BCL2 mRNA; Fluorouracil results in increased expression of BCL2 protein
[Fluorouracil co-treated with casticin] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]
Fluorouracil results in increased phosphorylation of BCL2 protein
Fluorouracil results in decreased expression of BCL-2 protein; Fluorouracil results in decreased expression of BCL2; Fluorouracil results in decreased expression of BCL2 mRNA; Fluorouracil results in decreased expression of BCL2 protein
BCL2 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:7654318 PMID:9388485 PMID:14503796 PMID:15177426 PMID:15754201 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
affects response to substance
increases expression
decreases expression
affects expression
decreases response to substance		 EXP
ISO		 3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA]; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2L1 protein]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]
BCL2L1 protein affects the susceptibility to Fluorouracil
3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; casticin promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]; Fluorouracil promotes the reaction [casticin results in decreased expression of BCL2L1 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
Fluorouracil results in increased expression of BCL2L1 mRNA; Fluorouracil results in increased expression of BCL2L1 protein
Fluorouracil results in decreased expression of BCL2L1; Fluorouracil results in decreased expression of BCL2L1 mRNA; Fluorouracil results in decreased expression of BCL2L1 protein
Fluorouracil affects the expression of BCL2L1 mRNA; Fluorouracil affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:12442003 PMID:15289866 PMID:15767554 PMID:16407826 PMID:16557594 More... NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions
increases expression		 EXP Fluorouracil affects the reaction [rebamipide results in decreased expression of BCL2L11 protein]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BCL2L11 protein] CTD PMID:29054700 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BCL2L12 BCL2 like 12 multiple interactions EXP [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2L12 mRNA CTD PMID:19015929 NCBI chr19:49,665,142...49,673,916
Ensembl chr19:49,665,142...49,673,916 		JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 decreases expression EXP Fluorouracil results in decreased expression of BDH1 protein CTD PMID:15585135 PMID:16803524 NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323 		JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA] CTD PMID:15016801 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BDNF brain derived neurotrophic factor decreases expression ISO Fluorouracil results in decreased expression of BDNF protein CTD PMID:18702703 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BEAN1 brain expressed associated with NEDD4 1 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of BEAN1 protein
BEAN1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr16:66,427,295...66,495,288
Ensembl chr16:66,427,295...66,493,529 		JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression		 EXP
ISO		 BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fluorouracil results in increased expression of BECN1 protein
Apigenin promotes the reaction [Fluorouracil results in increased expression of BECN1 protein]; Fluorouracil promotes the reaction [Apigenin results in increased expression of BECN1 protein]		 CTD PMID:16896004 PMID:28025107 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression ISO Fluorouracil results in increased expression of BGLAP mRNA CTD PMID:16888818 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 affects response to substance EXP BHLHE41 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037 		JBrowse link
G BID BH3 interacting domain death agonist multiple interactions
increases expression
decreases response to substance
decreases expression
increases response to substance		 EXP
ISO		 [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil results in increased cleavage of and results in increased activity of BID protein; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]
Fluorouracil results in increased expression of BID protein
casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein]
BID protein mutant form results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BID protein		 CTD PMID:15095271 PMID:15289866 PMID:15754201 PMID:21474236 PMID:32270916 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 increases expression EXP Fluorouracil results in increased expression of BIRC2 mRNA CTD PMID:17039268 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 increases expression
affects expression		 EXP Fluorouracil results in increased expression of BIRC3 mRNA
Fluorouracil affects the expression of BIRC3 mRNA		 CTD PMID:16557594 PMID:34151400 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases response to substance
increases expression
decreases expression
multiple interactions
affects response to substance		 EXP BIRC5 protein results in decreased susceptibility to Fluorouracil; BIRC5 results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased expression of BIRC5 mRNA; Fluorouracil results in increased expression of BIRC5 protein
Fluorouracil results in decreased expression of BIRC5 mRNA; Fluorouracil results in decreased expression of BIRC5 protein
[Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]; SM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein]
BIRC5 affects the susceptibility to Fluorouracil; BIRC5 protein affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 PMID:15685548 PMID:16217747 PMID:16546719 More... NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 affects response to substance
decreases response to substance		 EXP BIRC6 protein affects the susceptibility to Fluorouracil
BIRC6 results in decreased susceptibility to Fluorouracil		 CTD PMID:18239605 PMID:21542283 NCBI chr 2:32,357,023...32,618,878
Ensembl chr 2:32,357,023...32,619,571 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 decreases response to substance EXP BIRC7 protein results in decreased susceptibility to Fluorouracil CTD PMID:17437058 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G BLM BLM RecQ like helicase decreases expression ISO Fluorouracil results in decreased expression of BLM mRNA CTD PMID:19272435 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166 		JBrowse link
G BLVRB biliverdin reductase B affects response to substance EXP BLVRB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764 		JBrowse link
G BNIP1 BCL2 interacting protein 1 increases expression EXP Fluorouracil results in increased expression of BNIP1 mRNA CTD PMID:33770205 NCBI chr 5:173,144,531...173,164,387
Ensembl chr 5:173,144,442...173,164,387 		JBrowse link
G BNIP3 BCL2 interacting protein 3 multiple interactions
affects response to substance		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA]
BNIP3 affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:15067352 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like affects response to substance
decreases expression
increases expression		 EXP BNIP3L affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BNIP3L mRNA
Fluorouracil results in increased expression of BNIP3L mRNA		 CTD PMID:15067352 PMID:15109396 PMID:16557594 PMID:16709241 PMID:17039268 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636 		JBrowse link
G BOLL boule homolog, RNA binding protein multiple interactions EXP BOLL mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 2:197,726,890...197,786,206
Ensembl chr 2:197,726,879...197,786,762 		JBrowse link
G BOP1 BOP1 ribosomal biogenesis factor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA] CTD PMID:15016801 NCBI chr 8:144,262,045...144,291,438
Ensembl chr 8:144,262,045...144,291,438 		JBrowse link
G BORA BORA aurora kinase A activator decreases expression EXP Fluorouracil results in decreased expression of BORA mRNA CTD PMID:17374387 NCBI chr13:72,727,923...72,756,196
Ensembl chr13:72,727,749...72,756,198 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase decreases expression EXP Fluorouracil results in decreased expression of BRAF mRNA CTD PMID:38423379 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BRCA1 BRCA1 DNA repair associated increases expression
decreases expression
multiple interactions		 EXP Fluorouracil results in increased expression of BRCA1 mRNA
Fluorouracil results in decreased expression of BRCA1 mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA]		 CTD PMID:15607317 PMID:16101138 PMID:16557594 PMID:17982676 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRIX1 biogenesis of ribosomes BRX1 decreases expression EXP Fluorouracil results in decreased expression of BRIX1 mRNA CTD PMID:16510598 NCBI chr 5:34,915,711...34,925,996
Ensembl chr 5:34,915,677...34,925,996 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of BTG2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA]		 CTD PMID:15016801 PMID:17982676 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 multiple interactions EXP BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr21:17,593,653...17,612,901
Ensembl chr21:17,593,653...17,612,945 		JBrowse link
G BTN3A3 butyrophilin subfamily 3 member A3 increases expression EXP Fluorouracil results in increased expression of BTN3A3 mRNA CTD PMID:16101138 NCBI chr 6:26,440,504...26,453,415
Ensembl chr 6:26,440,472...26,453,415 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression EXP
ISO		 Fluorouracil results in decreased expression of BUB1 mRNA CTD PMID:16709241 PMID:19272435 NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B decreases expression EXP
ISO		 Fluorouracil results in decreased expression of BUB1B mRNA CTD PMID:16557594 PMID:16709241 PMID:19272435 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G BUB3 BUB3 mitotic checkpoint protein affects response to substance
decreases expression		 EXP BUB3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BUB3 protein		 CTD PMID:15548681 PMID:15585135 PMID:16803524 NCBI chr10:123,154,402...123,170,467
Ensembl chr10:123,154,402...123,170,467 		JBrowse link
G C11orf24 chromosome 11 open reading frame 24 affects response to substance EXP C11ORF24 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:68,261,338...68,271,973
Ensembl chr11:68,261,338...68,272,001 		JBrowse link
G C14orf132 chromosome 14 open reading frame 132 increases expression EXP Fluorouracil results in increased expression of C14ORF132 mRNA CTD PMID:16510598 NCBI chr14:96,039,362...96,093,971
Ensembl chr14:96,039,362...96,093,971 		JBrowse link
G C1orf35 chromosome 1 open reading frame 35 affects expression EXP Fluorouracil affects the expression of C1ORF35 mRNA CTD PMID:16584549 NCBI chr 1:228,100,731...228,103,325
Ensembl chr 1:228,100,726...228,105,411 		JBrowse link
G C4BPB complement component 4 binding protein beta affects expression EXP Fluorouracil affects the expression of C4BPB mRNA CTD PMID:16584549 NCBI chr 1:207,088,860...207,099,993
Ensembl chr 1:207,088,860...207,099,993 		JBrowse link
G CA12 carbonic anhydrase 12 multiple interactions EXP CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CA14 carbonic anhydrase 14 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA] CTD PMID:15016801 NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078 		JBrowse link
G CABYR calcium binding tyrosine phosphorylation regulated affects response to substance EXP CABYR protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr18:24,139,062...24,161,600
Ensembl chr18:24,138,987...24,161,600 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA] CTD PMID:15016801 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943 		JBrowse link
G CALB2 calbindin 2 increases response to substance
increases expression		 EXP CALB2 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of CALB2 mRNA		 CTD PMID:16510598 NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436 		JBrowse link
G CANX calnexin multiple interactions EXP CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA] CTD PMID:15016801 PMID:18678097 NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641 		JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 affects response to substance EXP CAP2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780 		JBrowse link
G CASD1 CAS1 domain containing 1 affects expression ISO Fluorouracil affects the expression of CASD1 mRNA CTD PMID:20421339 NCBI chr 7:94,509,809...94,634,172
Ensembl chr 7:94,509,219...94,557,019 		JBrowse link
G CASP1 caspase 1 increases cleavage EXP Fluorouracil results in increased cleavage of CASP1 protein CTD PMID:15162350 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP10 caspase 10 increases expression EXP Fluorouracil results in increased expression of CASP10 mRNA CTD PMID:34151400 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428 		JBrowse link
G CASP2 caspase 2 decreases expression EXP Fluorouracil results in decreased expression of CASP2 mRNA CTD PMID:34151400 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696 		JBrowse link
G CASP3 caspase 3 increases expression
increases cleavage
affects expression
multiple interactions
increases activity
decreases cleavage
decreases expression		 EXP
ISO		 Fluorouracil results in increased expression of CASP3; Fluorouracil results in increased expression of CASP3 mRNA; Fluorouracil results in increased expression of CASP3 protein; Fluorouracil results in increased expression of CASP3 protein modified form
Fluorouracil results in increased cleavage of CASP3 protein
Fluorouracil affects the expression of CASP3 mRNA
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in decreased cleavage of CASP3 protein]; Bosentan inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; Silybin inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]
Fluorouracil results in increased activity of CASP3 protein
Fluorouracil results in decreased cleavage of CASP3 protein
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP3 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP3; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP3 protein; [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein; [Fluorouracil co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased activity of CASP3 protein; [SM-1 compound co-treated with Fluorouracil] results in increased cleavage of CASP3 protein; [wogonin co-treated with Fluorouracil] results in increased activity of CASP3 protein; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; Celecoxib inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]; chan-yu-bao-yuan-tang promotes the reaction [Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP3 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [chan-yu-bao-yuan-tang results in increased cleavage of and results in increased expression of CASP3 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Fluorouracil results in increased activity of and results in increased cleavage of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein; HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [Fluorouracil results in decreased cleavage of CASP3 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]
Fluorouracil results in decreased expression of CASP3 mRNA
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; casticin inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP3 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form]		 CTD PMID:10891390 PMID:11300326 PMID:12414664 PMID:12934351 PMID:12941601 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of CASP4 protein
CASP4 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16217747 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CASP6 caspase 6 multiple interactions
affects expression		 EXP Fluorouracil results in increased cleavage of and results in increased activity of CASP6 protein; resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]; TP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]
Fluorouracil affects the expression of CASP6 mRNA		 CTD PMID:18497562 PMID:34151400 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CASP7 caspase 7 multiple interactions
increases expression
increases cleavage		 EXP [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein
Fluorouracil results in increased expression of CASP7 mRNA
Fluorouracil results in increased cleavage of CASP7 protein		 CTD PMID:16168113 PMID:26544897 PMID:34151400 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 multiple interactions
increases activity
increases cleavage
decreases expression
increases expression		 EXP
ISO		 [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP8 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP8; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP8 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP8 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein]; Cadmium Chloride affects the reaction [Fluorouracil results in decreased expression of CASP8 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; CASP8 results in increased susceptibility to [andrographolide co-treated with Fluorouracil]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; Fluorouracil affects the reaction [Cadmium Chloride results in decreased expression of CASP8 mRNA]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP8 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP8 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Fluorouracil results in increased activity of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]
Fluorouracil results in increased cleavage of CASP8 protein
Fluorouracil results in increased expression of CASP8 mRNA; Fluorouracil results in increased expression of CASP8 protein		 CTD PMID:10779637 PMID:10891390 PMID:12414664 PMID:14607657 PMID:15585135 More... NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity
decreases expression
increases expression
increases cleavage		 EXP
ISO		 [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of CASP9 mRNA; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP9; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP9 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP9 protein; Cadmium Chloride promotes the reaction [Fluorouracil results in decreased expression of CASP9 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP9 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]
Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; casticin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP9 protein]
Fluorouracil results in increased expression of CASP9 protein
Fluorouracil results in increased cleavage of CASP9 protein		 CTD PMID:10779637 PMID:12414664 PMID:15546879 PMID:15996812 PMID:16168113 More... NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions
decreases expression
decreases activity		 ISO
EXP		 Fluorouracil inhibits the reaction [casticin results in increased expression of CAT protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Luteolin results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Valsartan results in decreased activity of CAT protein]; Luteolin promotes the reaction [Fluorouracil results in decreased activity of CAT protein]; Valsartan promotes the reaction [Fluorouracil results in decreased activity of CAT protein]
[Fluorouracil co-treated with Leucovorin co-treated with 1,2-Dimethylhydrazine] results in increased expression of CAT protein; Silybin inhibits the reaction [Fluorouracil results in decreased expression of CAT protein]
[Fluorouracil co-treated with Arsenic Trioxide] results in decreased activity of CAT protein		 CTD PMID:27836789 PMID:29117755 PMID:31288002 PMID:32270916 PMID:32524861 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 affects response to substance
increases expression
decreases expression		 EXP CAV1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CAV1 mRNA
Fluorouracil results in decreased expression of CAV1 protein		 CTD PMID:15352031 PMID:24737281 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CAV2 caveolin 2 decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of CAV2 mRNA
Fluorouracil results in increased expression of CAV2 mRNA		 CTD PMID:16510598 PMID:24737281 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541 		JBrowse link
G CBR3 carbonyl reductase 3 affects expression ISO Fluorouracil affects the expression of CBR3 mRNA CTD PMID:20421339 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562 		JBrowse link
G CBS cystathionine beta-synthase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA] CTD PMID:15016801 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CBX1 chromobox 1 affects response to substance EXP CBX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478 		JBrowse link
G CCAT2 colon cancer associated transcript 2 decreases response to substance EXP CCAT2 results in decreased susceptibility to Fluorouracil CTD PMID:35968984 NCBI chr 8:127,400,399...127,402,150
Ensembl chr 8:127,400,399...127,402,150 		JBrowse link
G CCDC186 coiled-coil domain containing 186 increases expression EXP Fluorouracil results in increased expression of CCDC186 mRNA CTD PMID:16510598 NCBI chr10:114,120,862...114,174,220
Ensembl chr10:114,120,862...114,174,232 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CCL2 mRNA
Fluorouracil promotes the reaction [Valsartan results in decreased expression of CCL2 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of CCL2 mRNA]		 CTD PMID:35235860 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCN1 cellular communication network factor 1 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of CCN1 mRNA; Fluorouracil results in increased expression of CCN1 protein
CCN1 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:17699798 PMID:24737281 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCN2 cellular communication network factor 2 affects expression EXP Fluorouracil affects the expression of CCN2 mRNA CTD PMID:15205334 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCN3 cellular communication network factor 3 increases expression EXP Fluorouracil results in increased expression of CCN3 mRNA CTD PMID:16510598 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434 		JBrowse link
G CCNA1 cyclin A1 multiple interactions
affects expression		 EXP [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCNA1 protein; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCNA1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCNA1 mRNA]
Fluorouracil affects the expression of CCNA1 mRNA; Fluorouracil affects the expression of CCNA1 protein		 CTD PMID:23941782 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNA2 cyclin A2 multiple interactions
affects response to substance
affects expression
decreases expression		 EXP N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]
CCNA2 protein affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of CCNA2 mRNA
Fluorouracil results in decreased expression of CCNA2 mRNA; Fluorouracil results in decreased expression of CCNA2 protein		 CTD PMID:15205334 PMID:15546879 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 multiple interactions
decreases expression		 EXP N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]
Fluorouracil results in decreased expression of CCNB1 mRNA; Fluorouracil results in decreased expression of CCNB1 protein		 CTD PMID:15016801 PMID:15205334 PMID:15546879 PMID:16557594 PMID:17982676 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCNB2 cyclin B2 multiple interactions
decreases expression		 EXP
ISO		 TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA]
Fluorouracil results in decreased expression of CCNB2 mRNA; Fluorouracil results in decreased expression of CCNB2 protein		 CTD PMID:15016801 PMID:16557594 PMID:16709241 PMID:17982488 PMID:19272435 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045 		JBrowse link
G CCNC cyclin C decreases expression EXP Fluorouracil results in decreased expression of CCNC mRNA CTD PMID:16709241 NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825 		JBrowse link
G CCND1 cyclin D1 affects response to substance
decreases expression
multiple interactions
affects expression		 EXP
ISO		 CCND1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CCND1 protein
Fluorouracil promotes the reaction [Luteolin results in decreased expression of CCND1 protein]; Luteolin promotes the reaction [Fluorouracil results in decreased expression of CCND1 protein]
Fluorouracil affects the expression of CCND1 mRNA; Fluorouracil affects the expression of CCND1 protein
Fluorouracil results in decreased expression of CCND1 mRNA; Fluorouracil results in decreased expression of CCND1 protein
[allose co-treated with Fluorouracil] results in decreased expression of CCND1 protein; [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCND1 protein; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCND1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCND1 mRNA]; Fluorouracil promotes the reaction [allose results in decreased expression of CCND1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein]		 CTD PMID:15352031 PMID:17982676 PMID:18930000 PMID:23941782 PMID:31288002 More... NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 increases expression
decreases expression
multiple interactions
affects response to substance		 EXP
ISO		 Fluorouracil results in increased expression of CCND2 protein
Fluorouracil results in decreased expression of CCND2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA]
CCND2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:15352031 PMID:19272435 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCND3 cyclin D3 affects response to substance
increases expression		 EXP CCND3 affects the susceptibility to Fluorouracil; CCND3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCND3 mRNA		 CTD PMID:15067352 PMID:15548681 PMID:16709241 PMID:18383818 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357 		JBrowse link
G CCNE1 cyclin E1 decreases expression
multiple interactions
increases expression		 EXP Fluorouracil results in decreased expression of CCNE1 mRNA
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA; [Leucovorin co-treated with Fluorouracil] results in increased expression of CCNE1 mRNA
Fluorouracil results in increased expression of CCNE1 mRNA; Fluorouracil results in increased expression of CCNE1 protein		 CTD PMID:9930367 PMID:15342418 PMID:16101138 PMID:18930000 PMID:31587439 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CCNE2 cyclin E2 affects response to substance EXP CCNE2 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678 		JBrowse link
G CCNF cyclin F affects response to substance EXP CCNF affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr16:2,429,447...2,458,854
Ensembl chr16:2,429,394...2,458,854 		JBrowse link
G CCNG1 cyclin G1 affects response to substance
increases expression
multiple interactions
decreases expression		 EXP
ISO		 CCNG1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCNG1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA]
Fluorouracil results in decreased expression of CCNG1 mRNA		 CTD PMID:15152939 PMID:16217747 PMID:16557594 PMID:16709241 PMID:17982676 More... NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CCNG2 cyclin G2 affects response to substance
decreases expression
increases expression		 EXP
ISO		 CCNG2 affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CCNG2 mRNA
Fluorouracil results in increased expression of CCNG2 mRNA		 CTD PMID:15067352 PMID:16510598 PMID:16557594 PMID:17039268 PMID:18754885 More... NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCNJL cyclin J like affects expression EXP Fluorouracil affects the expression of CCNJL mRNA CTD PMID:16584549 NCBI chr 5:160,249,083...160,339,570
Ensembl chr 5:160,249,083...160,345,396 		JBrowse link
G CD109 CD109 molecule affects response to substance EXP CD109 protein affects the susceptibility to Fluorouracil CTD PMID:37661780 NCBI chr 6:73,679,192...73,828,313
Ensembl chr 6:73,695,785...73,828,316 		JBrowse link
G CD24 CD24 molecule increases expression EXP Fluorouracil results in increased expression of CD24 mRNA CTD PMID:16510598 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD274 CD274 molecule increases expression EXP Fluorouracil results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD34 CD34 molecule increases expression ISO Fluorouracil results in increased expression of CD34 protein CTD PMID:21296659 NCBI chr 1:207,880,972...207,911,125
Ensembl chr 1:207,880,972...207,911,402 		JBrowse link
G CD38 CD38 molecule affects expression EXP Fluorouracil affects the expression of CD38 mRNA CTD PMID:16584549 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G CD40 CD40 molecule decreases response to substance
multiple interactions		 EXP CD40 results in decreased susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]		 CTD PMID:15611226 PMID:20188757 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand multiple interactions EXP Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD44 CD44 molecule (IN blood group) multiple interactions ISO [gimeracil co-treated with Fluorouracil] results in decreased expression of CD44 CTD PMID:12364819 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CD52 CD52 molecule affects expression
multiple interactions		 EXP Fluorouracil affects the expression of CD52 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA]		 CTD PMID:15016801 PMID:16584549 NCBI chr 1:26,317,958...26,320,523
Ensembl chr 1:26,317,958...26,320,523 		JBrowse link
G CD63 CD63 molecule decreases expression EXP Fluorouracil results in decreased expression of CD63 CTD PMID:15485462 NCBI chr12:55,723,535...55,730,041
Ensembl chr12:55,725,323...55,729,707 		JBrowse link
G CD8A CD8 subunit alpha multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA] CTD PMID:15016801 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396 		JBrowse link
G CD8B CD8 subunit beta affects response to substance
decreases expression		 EXP CD8B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CD8B protein		 CTD PMID:15352031 NCBI chr 2:86,815,369...86,861,886
Ensembl chr 2:86,815,339...86,861,924 		JBrowse link
G CD9 CD9 molecule decreases expression ISO Fluorouracil results in decreased expression of CD9 protein CTD PMID:21296659 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CDA cytidine deaminase multiple interactions ISO [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil CTD PMID:10811482 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903 		JBrowse link
G CDC20 cell division cycle 20 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA] CTD PMID:15016801 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC25A cell division cycle 25A decreases expression EXP Fluorouracil results in decreased expression of CDC25A mRNA CTD PMID:16510598 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417 		JBrowse link
G CDC25B cell division cycle 25B decreases expression EXP
ISO		 Fluorouracil results in decreased expression of CDC25B mRNA CTD PMID:16709241 PMID:19272435 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121 		JBrowse link
G CDC25C cell division cycle 25C affects response to substance
decreases expression		 EXP
ISO		 CDC25C protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDC25C mRNA		 CTD PMID:15548681 PMID:19272435 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme affects response to substance EXP CDC34 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:531,760...542,087
Ensembl chr19:531,760...542,092 		JBrowse link
G CDC40 cell division cycle 40 increases expression EXP Fluorouracil results in increased expression of CDC40 protein CTD PMID:16803524 NCBI chr 6:110,180,427...110,232,232
Ensembl chr 6:110,180,141...110,254,275 		JBrowse link
G CDC42EP1 CDC42 effector protein 1 affects response to substance EXP CDC42EP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:37,560,480...37,569,405
Ensembl chr22:37,560,480...37,569,405 		JBrowse link
G CDC45 cell division cycle 45 multiple interactions
decreases expression
affects expression		 EXP
ISO		 [Leucovorin co-treated with Fluorouracil] results in increased expression of CDC45 mRNA
Fluorouracil results in decreased expression of CDC45 mRNA
Fluorouracil affects the expression of CDC45 mRNA		 CTD PMID:15342418 PMID:16557594 PMID:19272435 NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612 		JBrowse link
G CDC6 cell division cycle 6 affects expression
decreases expression
multiple interactions
increases expression		 EXP
ISO		 Fluorouracil affects the expression of CDC6 mRNA
Fluorouracil results in decreased expression of CDC6 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC6 mRNA
Fluorouracil results in increased expression of CDC6 mRNA		 CTD PMID:15342418 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657 		JBrowse link
G CDC73 cell division cycle 73 decreases expression EXP Fluorouracil results in decreased expression of CDC73 mRNA CTD PMID:16510598 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CDCA5 cell division cycle associated 5 increases expression EXP Fluorouracil results in increased expression of CDCA5 mRNA CTD PMID:16709241 NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164 		JBrowse link
G CDCA7 cell division cycle associated 7 affects expression ISO Fluorouracil affects the expression of CDCA7 mRNA CTD PMID:20421339 NCBI chr 2:173,354,872...173,368,997
Ensembl chr 2:173,354,820...173,368,997 		JBrowse link
G CDCA8 cell division cycle associated 8 decreases expression EXP Fluorouracil results in decreased expression of CDCA8 mRNA CTD PMID:17374387 NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719 		JBrowse link
G CDH1 cadherin 1 affects response to substance
decreases expression
multiple interactions		 EXP CDH1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDH1 protein
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CDH1 protein]		 CTD PMID:15352031 PMID:26310874 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH5 cadherin 5 increases expression
multiple interactions		 ISO
EXP		 Fluorouracil results in increased expression of CDH5 protein
Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]		 CTD PMID:21296659 PMID:31404653 NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784 		JBrowse link
G CDH6 cadherin 6 decreases expression EXP Fluorouracil results in decreased expression of CDH6 mRNA CTD PMID:24737281 NCBI chr 5:31,193,686...31,329,146
Ensembl chr 5:31,193,686...31,329,146 		JBrowse link
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase affects expression EXP Fluorouracil affects the expression of CDIPT mRNA CTD PMID:16584549 NCBI chr16:29,858,357...29,863,226
Ensembl chr16:29,858,357...29,863,414 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression
multiple interactions
increases expression
affects expression		 EXP
ISO		 Fluorouracil results in decreased expression of CDK1 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK1 mRNA
Fluorouracil results in increased expression of CDK1 mRNA
Fluorouracil affects the expression of CDK1 mRNA		 CTD PMID:15152939 PMID:15205334 PMID:15342418 PMID:16557594 PMID:17039268 More... NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK2 cyclin dependent kinase 2 affects response to substance
multiple interactions
increases expression		 EXP CDK2 protein affects the susceptibility to Fluorouracil; CDK2 protein modified form affects the susceptibility to Fluorouracil
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA
Fluorouracil results in increased expression of CDK2 mRNA		 CTD PMID:15342418 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 affects expression EXP Fluorouracil affects the expression of CDK5R1 mRNA CTD PMID:15205334 NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A affects response to substance
multiple interactions
increases expression
decreases degradation
decreases expression
decreases response to substance
increases response to substance		 EXP
ISO		 CDKN1A affects the susceptibility to Fluorouracil; CDKN1A protein affects the susceptibility to Fluorouracil
Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]
Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein
Fluorouracil results in increased expression of CDKN1A; Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein
Fluorouracil results in decreased degradation of CDKN1A protein
Fluorouracil results in decreased expression of CDKN1A mRNA; Fluorouracil results in decreased expression of CDKN1A protein
[Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA; [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased expression of CDKN1A protein; [Fluorouracil co-treated with Plant Extracts] results in increased expression of CDKN1A protein; [Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA; CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; CDKN1A protein affects the reaction [Fluorouracil results in decreased expression of UBE2C protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CDKN1A mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CDKN1A mRNA]; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of CDKN1A protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Simvastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]
CDKN1A protein results in decreased susceptibility to Fluorouracil
CDKN1A protein results in increased susceptibility to Fluorouracil		 CTD PMID:14646558 PMID:14665630 PMID:15016801 PMID:15067352 PMID:15205334 More... NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B affects response to substance
decreases expression		 EXP CDKN1B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDKN1B mRNA		 CTD PMID:17217824 PMID:18930000 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C affects response to substance
increases expression		 EXP
ISO		 CDKN1C affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CDKN1C mRNA		 CTD PMID:15067352 PMID:19272435 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A decreases expression EXP Fluorouracil results in decreased expression of CDKN2A protein CTD PMID:17982676 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN2AIP CDKN2A interacting protein affects response to substance EXP CDKN2AIP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:183,444,636...183,449,064
Ensembl chr 4:183,444,635...183,449,064 		JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C decreases expression EXP Fluorouracil results in decreased expression of CDKN2C mRNA CTD PMID:16557594 NCBI chr 1:50,960,745...50,974,634
Ensembl chr 1:50,960,745...50,974,634 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA] CTD PMID:15016801 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CDX2 caudal type homeobox 2 decreases expression ISO
EXP		 Fluorouracil results in decreased expression of CDX2 protein
Fluorouracil results in decreased expression of CDX2 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr13:27,960,918...27,969,315
Ensembl chr13:27,960,918...27,969,315 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression EXP Fluorouracil results in increased expression of CEBPB mRNA CTD PMID:16557594 PMID:16584549 PMID:34151400 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CENPQ centromere protein Q affects response to substance
increases expression		 EXP CENPQ protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CENPQ mRNA		 CTD PMID:15331170 NCBI chr 6:49,463,370...49,493,107
Ensembl chr 6:49,463,370...49,493,107 		JBrowse link
G CENPU centromere protein U affects response to substance EXP CENPU protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 4:184,694,085...184,734,096
Ensembl chr 4:184,694,085...184,734,130 		JBrowse link
G CENPX centromere protein X affects response to substance EXP CENPX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:82,018,703...82,022,878
Ensembl chr17:82,018,702...82,024,107 		JBrowse link
G CEP55 centrosomal protein 55 decreases expression EXP Fluorouracil results in decreased expression of CEP55 mRNA CTD PMID:17039268 NCBI chr10:93,496,612...93,529,092
Ensembl chr10:93,496,612...93,529,092 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist increases expression
decreases expression		 ISO
EXP		 Fluorouracil results in increased expression of CER1 mRNA
Fluorouracil results in decreased expression of CER1 mRNA		 CTD PMID:24737281 PMID:26272751 NCBI chr 9:14,717,326...14,722,733
Ensembl chr 9:14,719,724...14,722,733 		JBrowse link
G CES2 carboxylesterase 2 multiple interactions
increases expression		 EXP Fluorouracil promotes the reaction [TP53 protein binds to CES2 intron]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA] CTD PMID:15205334 PMID:16963839 PMID:17287894 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator multiple interactions
affects response to substance
decreases expression
increases expression		 EXP [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; [Fluorouracil results in decreased expression of CFLAR protein] which results in increased susceptibility to TNFSF10 protein; CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]; CFLAR protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]
CFLAR protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CFLAR mRNA; Fluorouracil results in decreased expression of CFLAR protein
Fluorouracil results in increased expression of CFLAR mRNA		 CTD PMID:15152939 PMID:15548681 PMID:16217747 PMID:16373718 PMID:17045692 More... NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHEK1 checkpoint kinase 1 affects response to substance
decreases expression
increases expression
multiple interactions		 EXP
ISO		 CHEK1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CHEK1 mRNA
Fluorouracil results in increased expression of CHEK1 protein
[CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK1 protein; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]		 CTD PMID:15016801 PMID:18698031 PMID:19272435 PMID:21613406 PMID:22194930 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255 		JBrowse link
G CHEK2 checkpoint kinase 2 multiple interactions EXP Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK2 protein CTD PMID:21613406 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G CHI3L1 chitinase 3 like 1 increases expression EXP Fluorouracil results in increased expression of CHI3L1 mRNA CTD PMID:15205334 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA] CTD PMID:15016801 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401 		JBrowse link
G CHST7 carbohydrate sulfotransferase 7 affects response to substance EXP CHST7 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:46,573,765...46,598,496
Ensembl chr  X:46,573,765...46,598,496 		JBrowse link
G CIAO1 cytosolic iron-sulfur assembly component 1 affects response to substance EXP CIAO1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 2:96,266,225...96,274,173
Ensembl chr 2:96,266,159...96,274,173 		JBrowse link
G CIDEB cell death inducing DFFA like effector b increases expression EXP Fluorouracil results in increased expression of CIDEB protein CTD PMID:15585135 PMID:16803524 NCBI chr14:24,305,187...24,311,435
Ensembl chr14:24,305,187...24,311,430 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 affects response to substance EXP CITED2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G CKB creatine kinase B affects response to substance EXP CKB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833 		JBrowse link
G CKS2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP
ISO		 Fluorouracil results in decreased expression of CKS2 mRNA CTD PMID:17374387 PMID:19272435 NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 affects response to substance EXP CLCN3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CLDN2 claudin 2 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of CLDN2 protein
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CLDN2 protein]		 CTD PMID:26310874 NCBI chr  X:106,900,164...106,930,861
Ensembl chr  X:106,900,164...106,930,861 		JBrowse link
G CLDN4 claudin 4 affects response to substance
decreases expression		 EXP CLDN4 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLDN4 protein		 CTD PMID:15352031 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690 		JBrowse link
G CLEC11A C-type lectin domain containing 11A affects response to substance
decreases expression		 EXP CLEC11A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLEC11A protein		 CTD PMID:15352031 NCBI chr19:50,723,364...50,725,708
Ensembl chr19:50,723,364...50,725,708 		JBrowse link
G CLIC1 chloride intracellular channel 1 affects response to substance EXP CLIC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763 		JBrowse link
G CLTC clathrin heavy chain multiple interactions EXP CLTC protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA] CTD PMID:15016801 PMID:18927307 NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956 		JBrowse link
G COCH cochlin affects response to substance EXP COCH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:30,874,559...30,895,615
Ensembl chr14:30,874,514...30,895,065 		JBrowse link
G COL12A1 collagen type XII alpha 1 chain decreases expression EXP Fluorouracil results in decreased expression of COL12A1 mRNA CTD PMID:15205334 PMID:16510598 NCBI chr 6:75,084,326...75,206,053
Ensembl chr 6:75,084,326...75,206,267 		JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of COL1A1 mRNA; Fluorouracil results in decreased expression of COL1A1 protein
Fluorouracil promotes the reaction [Valsartan results in decreased expression of COL1A1 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of COL1A1 mRNA]		 CTD PMID:21296659 PMID:35235860 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL1A2 collagen type I alpha 2 chain affects expression ISO Fluorouracil affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227 		JBrowse link
G COL2A1 collagen type II alpha 1 chain decreases expression ISO
EXP		 Fluorouracil results in decreased expression of COL2A1 protein
Fluorouracil results in decreased expression of COL2A1 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G COL3A1 collagen type III alpha 1 chain affects response to substance EXP COL3A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL4A2 collagen type IV alpha 2 chain affects response to substance
decreases expression		 EXP COL4A2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of COL4A2 protein		 CTD PMID:15352031 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209 		JBrowse link
G COL5A2 collagen type V alpha 2 chain affects response to substance EXP COL5A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain affects response to substance
multiple interactions		 EXP COL6A3 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328 		JBrowse link
G COX14 cytochrome c oxidase assembly factor COX14 affects expression EXP Fluorouracil affects the expression of COX14 mRNA CTD PMID:34151400 NCBI chr12:50,112,236...50,120,453
Ensembl chr12:50,112,082...50,120,457 		JBrowse link
G COX5B cytochrome c oxidase subunit 5B affects expression EXP Fluorouracil affects the expression of COX5B mRNA CTD PMID:34151400 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383 		JBrowse link
G COX6C cytochrome c oxidase subunit 6C affects expression EXP Fluorouracil affects the expression of COX6C mRNA CTD PMID:34151400 NCBI chr 8:99,877,865...99,893,707
Ensembl chr 8:99,873,200...99,893,707 		JBrowse link
G COX7C cytochrome c oxidase subunit 7C affects expression EXP Fluorouracil affects the expression of COX7C mRNA CTD PMID:34151400 NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962 		JBrowse link
G CP ceruloplasmin multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA] CTD PMID:15016801 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPA4 carboxypeptidase A4 decreases expression EXP Fluorouracil results in decreased expression of CPA4 mRNA CTD PMID:16510598 NCBI chr 7:130,293,161...130,324,180
Ensembl chr 7:130,293,134...130,324,180 		JBrowse link
G CPD carboxypeptidase D affects response to substance
multiple interactions		 EXP CPD protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989 		JBrowse link
G CPE carboxypeptidase E increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of CPE protein
CPE protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A affects response to substance EXP CPT1A protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CPXM1 carboxypeptidase X, M14 family member 1 affects expression EXP Fluorouracil affects the expression of CPXM1 mRNA CTD PMID:15205334 NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627 		JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 affects response to substance
increases expression		 EXP CRABP1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CRABP1 protein		 CTD PMID:15352031 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225 		JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 affects expression ISO Fluorouracil affects the expression of CRABP2 protein CTD PMID:21296659 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein affects expression EXP Fluorouracil affects the expression of CRHBP mRNA CTD PMID:15205334 NCBI chr 5:76,953,045...76,981,159
Ensembl chr 5:76,953,045...76,981,158 		JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 affects response to substance
increases expression
decreases expression		 EXP CRIM1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CRIM1 protein
Fluorouracil results in decreased expression of CRIM1 mRNA		 CTD PMID:15352031 PMID:16510598 NCBI chr 2:36,355,778...36,551,135
Ensembl chr 2:36,355,778...36,551,135 		JBrowse link
G CRIPTO cripto, EGF-CFC family member decreases expression ISO
EXP		 Fluorouracil results in decreased expression of CRIPTO protein
Fluorouracil results in decreased expression of CRIPTO mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr 3:46,574,535...46,582,457
Ensembl chr 3:46,574,534...46,582,457 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein affects response to substance EXP CRK protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162 		JBrowse link
G CRYGS crystallin gamma S multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA] CTD PMID:15016801 NCBI chr 3:186,538,443...186,544,380
Ensembl chr 3:186,538,441...186,546,702 		JBrowse link
G CRYL1 crystallin lambda 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA] CTD PMID:15016801 NCBI chr13:20,403,669...20,525,857
Ensembl chr13:20,403,666...20,525,873 		JBrowse link
G CRYZ crystallin zeta decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of CRYZ mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA]		 CTD PMID:17982676 NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408 		JBrowse link
G CSE1L chromosome segregation 1 like multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA] CTD PMID:15016801 NCBI chr20:49,046,312...49,096,949
Ensembl chr20:49,046,246...49,096,960 		JBrowse link
G CSF1 colony stimulating factor 1 affects response to substance EXP CSF1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CSF2 colony stimulating factor 2 increases expression ISO Fluorouracil results in increased expression of CSF2 mRNA CTD PMID:18344199 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSNK1E casein kinase 1 epsilon affects expression EXP Fluorouracil affects the expression of CSNK1E mRNA CTD PMID:16584549 NCBI chr22:38,290,691...38,318,084
Ensembl chr22:38,290,691...38,318,084 		JBrowse link
G CSRP1 cysteine and glycine rich protein 1 affects response to substance EXP CSRP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:201,483,530...201,507,123
Ensembl chr 1:201,483,530...201,509,456 		JBrowse link
G CST7 cystatin F affects response to substance
decreases expression		 EXP CST7 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CST7 protein		 CTD PMID:15352031 NCBI chr20:24,949,269...24,959,928
Ensembl chr20:24,949,269...24,959,928 		JBrowse link
G CST8 cystatin 8 affects expression EXP Fluorouracil affects the expression of CST8 mRNA CTD PMID:16584549 NCBI chr20:23,491,117...23,507,124
Ensembl chr20:23,491,101...23,496,010 		JBrowse link
G CSTF3 cleavage stimulation factor subunit 3 affects response to substance
increases expression		 EXP CSTF3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CSTF3 mRNA		 CTD PMID:15331170 NCBI chr11:33,084,584...33,161,480
Ensembl chr11:33,077,188...33,162,371 		JBrowse link
G CTBP2 C-terminal binding protein 2 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNA; CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:16391804 PMID:18927307 NCBI chr10:124,984,317...125,162,463
Ensembl chr10:124,984,317...125,161,170 		JBrowse link
G CTNND2 catenin delta 2 multiple interactions EXP CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:10,971,836...11,904,446
Ensembl chr 5:10,971,836...11,904,446 		JBrowse link
G CTPS1 CTP synthase 1 decreases expression EXP Fluorouracil results in decreased expression of CTPS1 mRNA CTD PMID:19219653 NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565 		JBrowse link
G CTSB cathepsin B multiple interactions
increases cleavage		 EXP CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CTSB protein] CTD PMID:19816940 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSH cathepsin H affects response to substance
increases expression		 EXP CTSH protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CTSH protein		 CTD PMID:15352031 NCBI chr15:78,921,058...78,945,046
Ensembl chr15:78,921,058...78,949,574 		JBrowse link
G CTTN cortactin decreases expression EXP Fluorouracil results in decreased expression of CTTN protein CTD PMID:15585135 PMID:16803524 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584 		JBrowse link
G CUL4A cullin 4A affects response to substance ISO CUL4A protein affects the susceptibility to Fluorouracil CTD PMID:16467204 NCBI chr13:113,208,193...113,267,108
Ensembl chr13:113,208,193...113,267,108 		JBrowse link
G CUL4B cullin 4B increases expression EXP Fluorouracil results in increased expression of CUL4B protein CTD PMID:16803524 NCBI chr  X:120,523,858...120,575,532
Ensembl chr  X:120,505,920...120,604,074 		JBrowse link
G CUL5 cullin 5 increases expression EXP Fluorouracil results in increased expression of CUL5 mRNA CTD PMID:16557594 NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761 		JBrowse link
G CUTC cutC copper transporter affects response to substance
multiple interactions		 EXP CUTC protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr10:99,732,234...99,756,134
Ensembl chr10:99,702,558...99,756,134 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression		 ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]
Fluorouracil results in increased expression of CXCL1 mRNA; Fluorouracil results in increased expression of CXCL1 protein		 CTD PMID:27194111 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 increases expression
affects expression		 ISO Fluorouracil results in increased expression of CXCL12 mRNA
Fluorouracil affects the expression of CXCL12 mRNA		 CTD PMID:16337237 PMID:18344199 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA] CTD PMID:27194111 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 affects expression
multiple interactions
increases secretion
increases expression		 EXP Fluorouracil affects the expression of CXCL8 mRNA
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL8 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased secretion of CXCL8 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Fluorouracil results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased secretion of CXCL8 protein]		 CTD PMID:16584549 PMID:35147423 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 multiple interactions EXP CXCR1 gene SNP affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:16098254 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 affects expression EXP Fluorouracil affects the expression of CXCR4 mRNA CTD PMID:16584549 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYC1 cytochrome c1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA] CTD PMID:15016801 NCBI chr 8:144,095,076...144,097,525
Ensembl chr 8:144,095,039...144,097,525 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA CTD PMID:32800223 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 affects response to substance
multiple interactions
increases expression		 EXP CYFIP2 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]		 CTD PMID:15016801 PMID:16217747 PMID:17039268 PMID:17982676 NCBI chr 5:157,266,123...157,395,594
Ensembl chr 5:157,266,079...157,395,595 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase increases response to substance EXP CYLD protein results in increased susceptibility to Fluorouracil CTD PMID:21109933 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases metabolic processing ISO CYP1A1 protein results in increased metabolism of Fluorouracil CTD PMID:17230597 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases chemical synthesis EXP CYP2A6 protein results in increased chemical synthesis of Fluorouracil CTD PMID:11376561 PMID:18212800 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 affects expression EXP Fluorouracil affects the expression of CYP2F1 mRNA CTD PMID:16584549 NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381 		JBrowse link
G CYP2S1 cytochrome P450 family 2 subfamily S member 1 affects expression ISO Fluorouracil affects the expression of CYP2S1 mRNA CTD PMID:20421339 NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 affects expression EXP Fluorouracil affects the expression of CYP3A4 mRNA CTD PMID:16584549 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 affects response to substance EXP CYP51A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G CYP51A1P2 cytochrome P450 family 51 subfamily A member 1 pseudogene 2 affects response to substance EXP CYP51A1P2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:28,720,868...28,724,155
Ensembl chr13:28,722,386...28,724,021 		JBrowse link
G CYTH3 cytohesin 3 decreases expression EXP Fluorouracil results in decreased expression of CYTH3 protein CTD PMID:15585135 PMID:16803524 NCBI chr 7:6,161,779...6,272,624
Ensembl chr 7:6,161,779...6,272,644 		JBrowse link
G DAPK1 death associated protein kinase 1 affects expression
increases expression		 ISO
EXP		 Fluorouracil affects the expression of DAPK1 mRNA
Fluorouracil results in increased expression of DAPK1 protein		 CTD PMID:20421339 PMID:30177839 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634 		JBrowse link
G DARS1 aspartyl-tRNA synthetase 1 affects expression EXP Fluorouracil affects the expression of DARS1 mRNA CTD PMID:16584549 NCBI chr 2:135,905,881...135,985,684
Ensembl chr 2:135,905,881...135,986,100 		JBrowse link
G DBF4 DBF4-CDC7 kinase regulatory subunit decreases expression EXP Fluorouracil results in decreased expression of DBF4 mRNA CTD PMID:16510598 NCBI chr 7:87,876,493...87,909,553
Ensembl chr 7:87,876,216...87,909,553 		JBrowse link
G DBNDD2 dysbindin domain containing 2 affects response to substance EXP DBNDD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:45,405,993...45,410,610
Ensembl chr20:45,406,057...45,410,610 		JBrowse link
G DCC DCC netrin 1 receptor multiple interactions EXP DCC protein results in increased susceptibility to [Fluorouracil co-treated with Levamisole] CTD PMID:15148649 NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899 		JBrowse link
G DCK deoxycytidine kinase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA] CTD PMID:15016801 NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914 		JBrowse link
G DCLK1 doublecortin like kinase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA] CTD PMID:15016801 NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382 		JBrowse link
G DCT dopachrome tautomerase affects expression EXP Fluorouracil affects the expression of DCT mRNA CTD PMID:15205334 NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682 		JBrowse link
G DCX doublecortin decreases expression ISO Fluorouracil results in decreased expression of DCX protein CTD PMID:18702703 NCBI chr  X:111,293,779...111,412,192
Ensembl chr  X:111,293,779...111,412,429 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA] CTD PMID:15016801 NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709 		JBrowse link
G DDAH2 DDAH family member 2, ADMA-independent affects response to substance EXP DDAH2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,727,040...31,730,263
Ensembl chr 6:31,727,038...31,730,617 		JBrowse link
G DDB2 damage specific DNA binding protein 2 affects response to substance
increases expression
multiple interactions		 EXP DDB2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of DDB2 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA]		 CTD PMID:15331170 PMID:16584549 PMID:17982676 PMID:22525470 NCBI chr11:47,214,454...47,239,217
Ensembl chr11:47,214,465...47,239,217 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Fluorouracil results in increased expression of DDIT3 mRNA; Fluorouracil results in increased expression of DDIT3 protein CTD PMID:17355264 PMID:29879413 PMID:32535746 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 increases expression EXP Fluorouracil results in increased expression of DDIT4 mRNA CTD PMID:16510598 PMID:16557594 PMID:17039268 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDX39B DExD-box helicase 39B increases expression EXP Fluorouracil results in increased expression of DDX39B mRNA CTD PMID:16510598 NCBI chr 6:31,530,226...31,542,003
Ensembl chr 6:31,530,219...31,542,448 		JBrowse link
G DDX4 DEAD-box helicase 4 increases expression ISO Fluorouracil results in increased expression of DDX4 protein CTD PMID:21296659 NCBI chr 5:55,738,061...55,817,157
Ensembl chr 5:55,738,017...55,817,157 		JBrowse link
G DENND2C DENN domain containing 2C affects expression ISO Fluorouracil affects the expression of DENND2C mRNA CTD PMID:20421339 NCBI chr 1:114,582,850...114,670,049
Ensembl chr 1:114,582,848...114,670,422 		JBrowse link
G DEPDC7 DEP domain containing 7 affects expression ISO Fluorouracil affects the expression of DEPDC7 mRNA CTD PMID:20421339 NCBI chr11:33,015,878...33,033,582
Ensembl chr11:33,015,876...33,033,582 		JBrowse link
G DES desmin decreases expression ISO Fluorouracil results in decreased expression of DES protein CTD PMID:21296659 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DFFA DNA fragmentation factor subunit alpha decreases expression EXP Fluorouracil results in decreased expression of DFFA mRNA CTD PMID:34151400 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529 		JBrowse link
G DHFR dihydrofolate reductase affects expression
increases expression		 EXP Fluorouracil affects the expression of DHFR mRNA
Fluorouracil results in increased expression of DHFR mRNA		 CTD PMID:15109396 PMID:16557594 PMID:21814787 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983 		JBrowse link
G DHX15 DEAH-box helicase 15 increases expression EXP Fluorouracil results in increased expression of DHX15 mRNA CTD PMID:16584549 NCBI chr 4:24,527,475...24,584,554
Ensembl chr 4:24,517,441...24,584,554 		JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein increases response to substance
increases expression		 EXP DIABLO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of DIABLO mRNA		 CTD PMID:16557594 PMID:18031615 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062 		JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression EXP Fluorouracil results in decreased expression of DICER1 mRNA CTD PMID:16510598 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DIMT1 DIM1 rRNA methyltransferase and ribosome maturation factor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA] CTD PMID:15016801 NCBI chr 5:62,387,254...62,403,905
Ensembl chr 5:62,347,284...62,403,943 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of DKK1 protein
DKK1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16217747 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G DKK4 dickkopf WNT signaling pathway inhibitor 4 increases expression EXP Fluorouracil results in increased expression of DKK4 mRNA CTD PMID:16584549 NCBI chr 8:42,374,063...42,391,322
Ensembl chr 8:42,374,063...42,377,229 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA] CTD PMID:15016801 NCBI chr 8:13,083,361...13,604,620
Ensembl chr 8:13,083,361...13,604,610 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 multiple interactions EXP DLG1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA]
Fluorouracil results in increased expression of DLK1 mRNA		 CTD PMID:15016801 PMID:24737281 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224 		JBrowse link
G DNAH2 dynein axonemal heavy chain 2 decreases expression EXP Fluorouracil results in decreased expression of DNAH2 mRNA CTD PMID:24737281 NCBI chr17:7,717,744...7,833,742
Ensembl chr17:7,717,744...7,833,742 		JBrowse link
G DNER delta/notch like EGF repeat containing increases expression EXP Fluorouracil results in increased expression of DNER mRNA CTD PMID:16510598 NCBI chr 2:229,357,629...229,714,555
Ensembl chr 2:229,357,629...229,714,555 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases expression ISO Fluorouracil results in decreased expression of DNMT3B protein CTD PMID:21296659 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DPAGT1 dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 affects response to substance EXP DPAGT1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:119,093,874...119,101,853
Ensembl chr11:119,096,025...119,108,331 		JBrowse link
G DPY19L1 dpy-19 like C-mannosyltransferase 1 affects response to substance EXP DPY19L1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:34,928,881...35,038,041
Ensembl chr 7:34,927,292...35,038,271 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase multiple interactions
decreases activity
decreases expression
increases metabolic processing
decreases response to substance
increases activity
increases expression
affects activity
increases degradation
decreases metabolic processing
affects degradation
increases response to substance
affects response to substance
affects metabolic processing		 EXP
ISO		 [Cisplatin co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [docetaxel co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [Leucovorin co-treated with Fluorouracil] results in decreased activity of DPYD protein; Camptothecin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; Cisplatin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; docetaxel inhibits the reaction [Fluorouracil results in increased activity of DPYD protein]; DPYD protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin]; DPYD results in increased susceptibility to [Fluorouracil co-treated with gimeracil]; Fluorouracil inhibits the reaction [docetaxel results in increased expression of DPYD protein]; gimeracil affects the reaction [DPYD protein results in increased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in decreased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased degradation of Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased metabolism of Fluorouracil]
Fluorouracil results in decreased activity of DPYD protein
Fluorouracil results in decreased expression of DPYD mRNA
DPYD mRNA results in decreased susceptibility to Fluorouracil; DPYD protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased expression of DPYD mRNA; Fluorouracil results in increased expression of DPYD protein
Fluorouracil metabolite affects the activity of DPYD protein
DPYD gene polymorphism results in decreased metabolism of Fluorouracil; DPYD protein mutant form results in decreased metabolism of Fluorouracil
DPYD protein affects the degradation of Fluorouracil
DPYD gene mutant form results in increased susceptibility to Fluorouracil; DPYD gene polymorphism results in increased susceptibility to Fluorouracil; DPYD mRNA results in increased susceptibility to Fluorouracil
DPYD gene polymorphism affects the susceptibility to Fluorouracil; DPYD gene SNP affects the susceptibility to Fluorouracil; DPYD intron polymorphism affects the susceptibility to Fluorouracil; DPYD mRNA affects the susceptibility to Fluorouracil; DPYD promoter modified form affects the susceptibility to Fluorouracil; DPYD protein affects the susceptibility to Fluorouracil; DPYD protein mutant form affects the susceptibility to Fluorouracil
DPYD affects the metabolism of Fluorouracil; DPYD protein affects the metabolism of Fluorouracil		 CTD PMID:3335642 PMID:7503095 PMID:8680084 PMID:9470816 PMID:9816193 More... NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DPYSL3 dihydropyrimidinase like 3 affects expression EXP Fluorouracil affects the expression of DPYSL3 mRNA CTD PMID:15205334 NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068 		JBrowse link
G DRAM1 DNA damage regulated autophagy modulator 1 multiple interactions
increases expression		 EXP
ISO		 TP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA]
Fluorouracil promotes the reaction [Luteolin results in increased expression of DRAM1 protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of DRAM1 protein]		 CTD PMID:17982676 PMID:31288002 NCBI chr12:101,877,580...101,923,612
Ensembl chr12:101,877,580...102,012,130 		JBrowse link
G DRD5 dopamine receptor D5 multiple interactions EXP DRD5 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G DST dystonin affects response to substance EXP DST protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830 		JBrowse link
G DTWD1 DTW domain containing 1 increases expression EXP Fluorouracil results in increased expression of DTWD1 mRNA CTD PMID:33770205 NCBI chr15:49,621,048...49,656,232
Ensembl chr15:49,621,037...49,656,232 		JBrowse link
G DTYMK deoxythymidylate kinase affects response to substance
multiple interactions
increases expression		 EXP DTYMK affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA]
Fluorouracil results in increased expression of DTYMK mRNA		 CTD PMID:15016801 PMID:15067352 PMID:15109396 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944 		JBrowse link
G DUSP14 dual specificity phosphatase 14 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA] CTD PMID:15016801 NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501 		JBrowse link
G DUSP5 dual specificity phosphatase 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA] CTD PMID:15016801 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP6 dual specificity phosphatase 6 increases expression EXP Fluorouracil results in increased expression of DUSP6 mRNA CTD PMID:16510598 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G DUT deoxyuridine triphosphatase decreases response to substance
decreases expression		 EXP DUT protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of DUT mRNA		 CTD PMID:16557594 PMID:19015155 NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373 		JBrowse link
G E2F1 E2F transcription factor 1 decreases expression EXP Fluorouracil results in decreased expression of E2F1 mRNA CTD PMID:34151400 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F2 E2F transcription factor 2 decreases expression EXP Fluorouracil results in decreased expression of E2F2; Fluorouracil results in decreased expression of E2F2 mRNA CTD PMID:11300326 PMID:34151400 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233 		JBrowse link
G E2F3 E2F transcription factor 3 multiple interactions EXP E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714 		JBrowse link
G E2F4 E2F transcription factor 4 multiple interactions
decreases expression		 EXP CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]
Fluorouracil results in decreased expression of E2F4 mRNA		 CTD PMID:27129209 PMID:34151400 NCBI chr16:67,192,155...67,198,918
Ensembl chr16:67,192,155...67,198,918 		JBrowse link
G E2F8 E2F transcription factor 8 affects expression EXP Fluorouracil affects the expression of E2F8 mRNA CTD PMID:16584549 NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620 		JBrowse link
G EBP EBP cholestenol delta-isomerase affects response to substance EXP EBP protein affects the susceptibility to Fluorouracil CTD PMID:15548681 PMID:16217747 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G ECHDC3 enoyl-CoA hydratase domain containing 3 affects response to substance EXP ECHDC3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:11,742,382...11,764,070
Ensembl chr10:11,742,366...11,764,070 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 increases expression EXP Fluorouracil results in increased expression of ECHS1 mRNA CTD PMID:15152939 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G ECT2 epithelial cell transforming 2 multiple interactions
decreases expression		 EXP TP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA] CTD PMID:17982676 NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474 		JBrowse link
G EDIL3 EGF like repeats and discoidin domains 3 affects response to substance EXP EDIL3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 5:83,940,554...84,384,880
Ensembl chr 5:83,940,554...84,384,880 		JBrowse link
G EDN1 endothelin 1 increases expression EXP Fluorouracil results in increased expression of EDN1 mRNA; Fluorouracil results in increased expression of EDN1 protein CTD PMID:1606078 PMID:19098008 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A affects response to substance EXP EDNRA protein affects the susceptibility to Fluorouracil CTD PMID:17032313 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B decreases expression EXP Fluorouracil results in decreased expression of EDNRB mRNA CTD PMID:24737281 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 increases expression
affects expression
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of EEF1A1 mRNA
Fluorouracil affects the expression of EEF1A1 protein
TP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]		 CTD PMID:17982676 PMID:21296659 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G EEIG1 estrogen-induced osteoclastogenesis regulator 1 affects expression EXP Fluorouracil affects the expression of EEIG1 mRNA CTD PMID:16584549 NCBI chr 9:127,940,582...127,980,989
Ensembl chr 9:127,940,582...127,980,989 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Fluorouracil results in increased expression of EFEMP1 mRNA CTD PMID:24737281 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139 		JBrowse link
G EFHD1 EF-hand domain family member D1 affects response to substance EXP EFHD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:232,606,057...232,682,776
Ensembl chr 2:232,606,057...232,682,776 		JBrowse link
G EFHD2 EF-hand domain family member D2 decreases expression EXP Fluorouracil results in decreased expression of EFHD2 mRNA CTD PMID:16510598 NCBI chr 1:15,409,888...15,430,339
Ensembl chr 1:15,409,888...15,430,339 		JBrowse link
G EFNB2 ephrin B2 affects response to substance
decreases expression		 EXP EFNB2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of EFNB2 protein		 CTD PMID:15352031 PMID:16217747 NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP [Fluorouracil co-treated with EGF protein] results in increased expression of MT2A mRNA; EGF protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]] CTD PMID:28507149 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
multiple interactions		 EXP EGFR gene polymorphism results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of EGFR protein
Fluorouracil results in increased phosphorylation of EGFR protein
EGFR protein affects the susceptibility to Fluorouracil
[Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA; EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil]; EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil]; EGFR results in increased susceptibility to [Cisplatin co-treated with docetaxel co-treated with Fluorouracil]; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of EGFR protein; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein]		 CTD PMID:15737843 PMID:15981280 PMID:16098254 PMID:16836928 PMID:17169374 More... NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 multiple interactions
affects expression
affects localization
increases expression
decreases expression		 EXP EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 mRNA]; EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 protein]; Fluorouracil promotes the reaction [EGR1 protein binds to THBS1 promoter]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 protein]
Fluorouracil affects the expression of EGR1 mRNA
Fluorouracil affects the localization of EGR1 protein
Fluorouracil results in decreased expression of EGR1 mRNA		 CTD PMID:15205334 PMID:16557594 PMID:17039268 PMID:18757417 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EHD2 EH domain containing 2 affects response to substance EXP EHD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134 		JBrowse link
G EHF ETS homologous factor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA] CTD PMID:15016801 NCBI chr11:34,621,093...34,663,288
Ensembl chr11:34,621,093...34,663,288 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression		 EXP Fluorouracil results in increased phosphorylation of EIF2AK3 protein
Fluorouracil results in increased expression of EIF2AK3 mRNA		 CTD PMID:29879413 PMID:32535746 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2B2 eukaryotic translation initiation factor 2B subunit beta decreases expression EXP Fluorouracil results in decreased expression of EIF2B2 protein CTD PMID:15585135 PMID:16803524 NCBI chr14:75,002,921...75,012,366
Ensembl chr14:75,002,921...75,012,366 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Fluorouracil results in increased phosphorylation of EIF2S1 protein CTD PMID:29879413 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H increases expression EXP Fluorouracil results in increased expression of EIF3H protein CTD PMID:15585135 PMID:16803524 NCBI chr 8:116,642,130...116,766,374
Ensembl chr 8:116,642,130...116,766,925 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of EIF4E mRNA
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA]		 CTD PMID:15016801 PMID:15611226 PMID:16584549 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G EIF4H eukaryotic translation initiation factor 4H increases expression EXP Fluorouracil results in increased expression of EIF4H protein CTD PMID:15585135 PMID:16803524 NCBI chr 7:74,174,356...74,197,096
Ensembl chr 7:74,174,231...74,197,122 		JBrowse link
G EIF5 eukaryotic translation initiation factor 5 increases expression EXP Fluorouracil results in increased expression of EIF5 mRNA CTD PMID:17039268 NCBI chr14:103,334,237...103,345,025
Ensembl chr14:103,333,544...103,345,025 		JBrowse link
G EIPR1 EARP complex and GARP complex interacting protein 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA] CTD PMID:15016801 NCBI chr 2:3,188,970...3,377,818
Ensembl chr 2:3,188,925...3,377,830 		JBrowse link
G ELMO2 engulfment and cell motility 2 increases expression EXP Fluorouracil results in increased expression of ELMO2 protein CTD PMID:16803524 NCBI chr20:46,366,050...46,406,615
Ensembl chr20:46,366,050...46,432,985 		JBrowse link
G ELN elastin affects expression EXP Fluorouracil affects the expression of ELN mRNA CTD PMID:15205334 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G ELOA elongin A affects expression EXP Fluorouracil affects the expression of ELOA mRNA CTD PMID:15205334 NCBI chr 1:23,743,471...23,762,059
Ensembl chr 1:23,743,448...23,762,059 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 affects response to substance EXP ELOVL5 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:53,267,404...53,348,950
Ensembl chr 6:53,267,398...53,349,179 		JBrowse link
G EMC1 ER membrane protein complex subunit 1 affects expression EXP Fluorouracil affects the expression of EMC1 mRNA CTD PMID:16584549 NCBI chr 1:19,215,660...19,251,524
Ensembl chr 1:19,215,660...19,251,552 		JBrowse link
G EML2 EMAP like 2 multiple interactions EXP EML2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr19:45,609,400...45,645,629
Ensembl chr19:45,606,994...45,645,602 		JBrowse link
G EMP3 epithelial membrane protein 3 (MAM blood group) increases expression ISO Fluorouracil results in increased expression of EMP3 mRNA CTD PMID:19272435 NCBI chr19:48,325,552...48,330,553
Ensembl chr19:48,321,310...48,330,559 		JBrowse link
G ENAH ENAH actin regulator affects response to substance EXP ENAH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:225,486,829...225,653,878
Ensembl chr 1:225,486,765...225,653,142 		JBrowse link
G ENDOG endonuclease G multiple interactions
increases expression		 ISO casticin inhibits the reaction [Fluorouracil results in increased expression of ENDOG protein] CTD PMID:32270916 NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676 		JBrowse link
G ENOSF1 enolase superfamily member 1 affects response to substance
decreases response to substance		 EXP ENOSF1 protein affects the susceptibility to Fluorouracil
ENOSF1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:15548681 PMID:18357371 NCBI chr18:662,986...712,630
Ensembl chr18:670,318...712,662 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 decreases expression EXP Fluorouracil results in decreased expression of ENTPD1 mRNA CTD PMID:19219653 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G ENTREP3 endosomal transmembrane epsin interactor 3 affects response to substance EXP ENTREP3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:155,247,205...155,255,483
Ensembl chr 1:155,247,205...155,255,483 		JBrowse link
G EOMES eomesodermin decreases expression ISO Fluorouracil results in decreased expression of EOMES protein CTD PMID:21296659 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711 		JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP Fluorouracil promotes the reaction [EP300 protein binds to UBE2C promoter] CTD PMID:27129209 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EP400 E1A binding protein p400 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA] CTD PMID:15016801 NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 increases expression EXP Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 affects expression ISO Fluorouracil affects the expression of EPB41L3 mRNA CTD PMID:20421339 NCBI chr18:5,392,386...5,630,663
Ensembl chr18:5,392,381...5,630,700 		JBrowse link
G EPHA2 EPH receptor A2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA] CTD PMID:15016801 NCBI chr 1:16,124,337...16,156,069
Ensembl chr 1:16,124,337...16,156,069 		JBrowse link
G EPHX1 epoxide hydrolase 1 affects response to substance
increases expression		 EXP EPHX1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPHX1 mRNA		 CTD PMID:15205334 PMID:16217747 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPO erythropoietin increases response to substance
increases expression		 EXP
ISO		 EPO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPO protein		 CTD PMID:2206997 PMID:16103069 PMID:20020992 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPOR erythropoietin receptor affects response to substance ISO EPOR gene mutant form affects the susceptibility to Fluorouracil CTD PMID:16511603 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G EPPK1 epiplakin 1 increases expression EXP Fluorouracil results in increased expression of EPPK1 mRNA CTD PMID:16510598 NCBI chr 8:143,857,324...143,879,194
Ensembl chr 8:143,857,324...143,878,467 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 decreases expression EXP Fluorouracil results in decreased expression of EPRS1 mRNA CTD PMID:16709241 NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530 		JBrowse link
G EPYC epiphycan affects expression EXP Fluorouracil affects the expression of EPYC mRNA CTD PMID:15205334 NCBI chr12:90,963,682...91,004,972
Ensembl chr12:90,963,682...91,005,026 		JBrowse link
G ERAS ES cell expressed Ras decreases expression ISO Fluorouracil results in decreased expression of ERAS protein CTD PMID:21296659 NCBI chr  X:48,826,513...48,829,869
Ensembl chr  X:48,826,513...48,830,138 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
affects response to substance
affects expression
decreases response to substance		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; [Apigenin co-treated with Fluorouracil] results in decreased expression of ERBB2 protein; [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERBB2 mRNA; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein
Fluorouracil results in decreased expression of ERBB2 protein
ERBB2 mRNA alternative form affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of ERBB2 mRNA
ERBB2 mRNA results in decreased susceptibility to Fluorouracil; ERBB2 results in decreased susceptibility to Fluorouracil		 CTD PMID:9816327 PMID:15205334 PMID:15737843 PMID:15940066 PMID:16446318 More... NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 multiple interactions EXP Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein CTD PMID:17918158 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions
decreases expression		 EXP [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA; ERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; ERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]; ERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]; ERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil]
Fluorouracil results in decreased expression of ERCC1 mRNA		 CTD PMID:15173087 PMID:15213713 PMID:15737843 PMID:17016597 PMID:17401013 More... NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions EXP ERCC2 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; ERCC2 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin] CTD PMID:15213713 PMID:17401013 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G EREG epiregulin decreases expression EXP Fluorouracil results in decreased expression of EREG mRNA CTD PMID:16510598 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression EXP Fluorouracil results in increased expression of ERN1 mRNA CTD PMID:32535746 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 decreases expression EXP Fluorouracil results in decreased expression of ERP29 protein CTD PMID:15585135 PMID:16803524 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G ESPL1 extra spindle pole bodies like 1, separase affects response to substance EXP ESPL1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr12:53,268,299...53,293,638
Ensembl chr12:53,268,299...53,293,638 		JBrowse link
G ETF1 eukaryotic translation termination factor 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA] CTD PMID:15016801 NCBI chr 5:138,506,095...138,543,236
Ensembl chr 5:138,506,095...138,543,236 		JBrowse link
G ETFB electron transfer flavoprotein subunit beta affects response to substance EXP ETFB protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA]
Fluorouracil results in increased expression of ETS1 protein		 CTD PMID:15016801 PMID:30177839 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G ETV2 ETS variant transcription factor 2 multiple interactions EXP Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr19:35,641,745...35,644,871
Ensembl chr19:35,641,745...35,644,871 		JBrowse link
G EXO1 exonuclease 1 affects response to substance EXP HEXO1 protein affects the susceptibility to Fluorouracil CTD PMID:16477629 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148 		JBrowse link
G EXOSC10 exosome component 10 affects response to substance
increases metabolic processing		 EXP EXOSC10 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased metabolism of EXOSC10 protein		 CTD PMID:18567802 NCBI chr 1:11,066,618...11,099,869
Ensembl chr 1:11,066,618...11,099,869 		JBrowse link
G F12 coagulation factor XII affects response to substance
decreases expression		 EXP F12 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of F12 protein		 CTD PMID:15352031 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G F2 coagulation factor II, thrombin decreases expression EXP Fluorouracil results in decreased expression of F2 mRNA CTD PMID:16709241 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F3 coagulation factor III, tissue factor decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of F3 mRNA
F3 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:16510598 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F8 coagulation factor VIII multiple interactions EXP F8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940 		JBrowse link
G FABP7 fatty acid binding protein 7 decreases expression EXP Fluorouracil results in decreased expression of FABP7 mRNA CTD PMID:24737281 NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074 		JBrowse link
G FADD Fas associated via death domain decreases expression EXP Fluorouracil results in decreased expression of FADD mRNA CTD PMID:34151400 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FADS1 fatty acid desaturase 1 affects response to substance EXP FADS1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318 		JBrowse link
G FAH fumarylacetoacetate hydrolase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA] CTD PMID:15016801 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946 		JBrowse link
G FAM107B family with sequence similarity 107 member B multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA] CTD PMID:15016801 NCBI chr10:14,518,557...14,774,897
Ensembl chr10:14,518,557...14,774,897 		JBrowse link
G FAM114A1 family with sequence similarity 114 member A1 affects expression EXP Fluorouracil affects the expression of FAM114A1 mRNA CTD PMID:16584549 NCBI chr 4:38,867,806...38,945,739
Ensembl chr 4:38,867,677...38,945,739 		JBrowse link
G FAM171A1 family with sequence similarity 171 member A1 affects response to substance EXP FAM171A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:15,211,643...15,374,554
Ensembl chr10:15,211,643...15,371,289 		JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase affects expression EXP Fluorouracil affects the expression of FAM20C mRNA CTD PMID:16584549 NCBI chr 7:192,571...260,772
Ensembl chr 7:192,571...260,772 		JBrowse link
G FAM234B family with sequence similarity 234 member B multiple interactions EXP FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:13,044,381...13,083,449
Ensembl chr12:13,044,381...13,142,521 		JBrowse link
G FAM76B family with sequence similarity 76 member B decreases expression EXP Fluorouracil results in decreased expression of FAM76B mRNA CTD PMID:16510598 NCBI chr11:95,768,953...95,789,782
Ensembl chr11:95,768,953...95,790,409 		JBrowse link
G FANCC FA complementation group C decreases expression EXP Fluorouracil results in decreased expression of FANCC mRNA CTD PMID:16557594 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G FANCG FA complementation group G increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of FANCG mRNA
FANCG affects the susceptibility to Fluorouracil; FANCG protein affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 PMID:15548681 NCBI chr 9:35,073,839...35,079,942
Ensembl chr 9:35,073,835...35,080,004 		JBrowse link
G FANCI FA complementation group I affects response to substance EXP FANCI protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr15:89,243,979...89,317,259
Ensembl chr15:89,243,945...89,317,261 		JBrowse link
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial decreases expression EXP Fluorouracil results in decreased expression of FARS2 mRNA CTD PMID:16101138 NCBI chr 6:5,249,934...5,771,583
Ensembl chr 6:5,261,044...5,829,192 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions
increases expression		 EXP [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of FAS mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of FAS protein; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]
Fluorouracil results in increased expression of FAS; Fluorouracil results in increased expression of FAS mRNA; Fluorouracil results in increased expression of FAS protein		 CTD PMID:11300326 PMID:14665630 PMID:15016801 PMID:15034078 PMID:15152939 More... NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand increases response to substance
increases expression		 ISO FASL results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of FASL		 CTD PMID:11196169 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FASTK Fas activated serine/threonine kinase decreases expression EXP Fluorouracil results in decreased expression of FASTK mRNA CTD PMID:34151400 NCBI chr 7:151,076,624...151,080,809
Ensembl chr 7:151,076,624...151,080,866 		JBrowse link
G FBLN1 fibulin 1 affects expression
increases expression		 EXP Fluorouracil affects the expression of FBLN1 mRNA
Fluorouracil results in increased expression of FBLN1 mRNA		 CTD PMID:15205334 PMID:17039268 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FBXO5 F-box protein 5 decreases expression EXP
ISO		 Fluorouracil results in decreased expression of FBXO5 mRNA CTD PMID:16557594 PMID:19272435 NCBI chr 6:152,970,535...152,983,579
Ensembl chr 6:152,970,519...152,983,579 		JBrowse link
G FDXR ferredoxin reductase multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein]
Fluorouracil results in increased expression of FDXR mRNA; Fluorouracil results in increased expression of FDXR mRNA alternative form; Fluorouracil results in increased expression of FDXR protein		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:17982676 More... NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 affects response to substance
increases expression		 EXP FEN1 affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FEN1 mRNA		 CTD PMID:15067352 PMID:15109396 NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 affects response to substance EXP FERMT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:52,857,273...52,951,050
Ensembl chr14:52,857,268...52,952,435 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 affects response to substance EXP FGD6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FGF2 fibroblast growth factor 2 decreases expression EXP Fluorouracil results in decreased expression of FGF2 mRNA CTD PMID:16510598 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF4 fibroblast growth factor 4 affects expression ISO Fluorouracil affects the expression of FGF4 protein CTD PMID:21296659 NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341 		JBrowse link
G FGF5 fibroblast growth factor 5 decreases expression ISO Fluorouracil results in decreased expression of FGF5 protein CTD PMID:21296659 NCBI chr 4:80,266,588...80,291,017
Ensembl chr 4:80,266,639...80,336,680 		JBrowse link
G FGF7 fibroblast growth factor 7 decreases response to substance
multiple interactions		 EXP FGF7 protein results in decreased susceptibility to Fluorouracil; FGF7 results in decreased susceptibility to Fluorouracil
FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil]		 CTD PMID:18575591 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 multiple interactions EXP FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil] CTD PMID:18575591 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FGG fibrinogen gamma chain decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of FGG mRNA
FGG protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:17039268 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G FHL2 four and a half LIM domains 2 affects response to substance EXP FHL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G FHL3 four and a half LIM domains 3 increases expression EXP Fluorouracil results in increased expression of FHL3 mRNA CTD PMID:17039268 NCBI chr 1:37,996,770...38,005,514
Ensembl chr 1:37,996,764...38,005,606 		JBrowse link
G FIBCD1 fibrinogen C domain containing 1 decreases expression EXP Fluorouracil results in decreased expression of FIBCD1 mRNA CTD PMID:34151400 NCBI chr 9:130,902,440...130,940,709
Ensembl chr 9:130,902,438...130,939,286 		JBrowse link
G FILIP1L filamin A interacting protein 1 like affects response to substance
increases expression		 EXP FILIP1L protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FILIP1L protein		 CTD PMID:15352031 NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513 		JBrowse link
G FKBP11 FKBP prolyl isomerase 11 affects response to substance EXP FKBP11 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:48,921,963...48,939,034
Ensembl chr12:48,921,518...48,926,474 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B affects response to substance EXP FKBP1B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:24,033,206...24,063,681
Ensembl chr 2:24,049,701...24,063,681 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA] CTD PMID:15016801 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FKBPL FKBP prolyl isomerase like increases expression EXP Fluorouracil results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr 6:32,128,707...32,130,288
Ensembl chr 6:32,128,707...32,130,288 		JBrowse link
G FLRT2 fibronectin leucine rich transmembrane protein 2 affects response to substance EXP FLRT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:85,530,144...85,654,428
Ensembl chr14:85,530,144...85,654,428 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of FLT1 protein
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein]		 CTD PMID:18157009 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FMOD fibromodulin multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA] CTD PMID:15016801 NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758 		JBrowse link
G FN1 fibronectin 1 decreases expression ISO Fluorouracil results in decreased expression of FN1 protein CTD PMID:21296659 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FNBP1 formin binding protein 1 affects response to substance EXP FNBP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:129,887,187...130,053,879
Ensembl chr 9:129,887,187...130,043,189 		JBrowse link
G FNDC3B fibronectin type III domain containing 3B decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of FNDC3B mRNA
FNDC3B protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16510598 NCBI chr 3:172,039,578...172,401,669
Ensembl chr 3:172,039,578...172,401,669 		JBrowse link
G FOLR1 folate receptor alpha decreases expression EXP Fluorouracil results in decreased expression of FOLR1 mRNA CTD PMID:16510598 NCBI chr11:72,189,709...72,196,323
Ensembl chr11:72,189,558...72,196,323 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
affects expression		 EXP Fluorouracil results in increased expression of FOS mRNA
Fluorouracil affects the expression of FOS mRNA		 CTD PMID:15205334 PMID:17039268 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit affects expression EXP Fluorouracil affects the expression of FOSL1 mRNA CTD PMID:34151400 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOXA2 forkhead box A2 decreases expression ISO Fluorouracil results in decreased expression of FOXA2 protein CTD PMID:21296659 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455 		JBrowse link
G FOXC1 forkhead box C1 affects expression EXP Fluorouracil affects the expression of FOXC1 mRNA CTD PMID:16584549 NCBI chr 6:1,609,915...1,613,897
Ensembl chr 6:1,609,915...1,613,897 		JBrowse link
G FOXD3 forkhead box D3 decreases expression ISO Fluorouracil results in decreased expression of FOXD3 protein CTD PMID:21296659 NCBI chr 1:63,322,567...63,325,128
Ensembl chr 1:63,322,567...63,325,128 		JBrowse link
G FOXG1 forkhead box G1 decreases expression EXP Fluorouracil results in decreased expression of FOXG1 mRNA CTD PMID:30518710 NCBI chr14:28,766,787...28,770,277
Ensembl chr14:28,764,329...28,770,277 		JBrowse link
G FOXL2 forkhead box L2 increases expression EXP Fluorouracil results in increased expression of FOXL2 mRNA CTD PMID:34151400 NCBI chr 3:138,944,224...138,947,137
Ensembl chr 3:138,944,224...138,947,137 		JBrowse link
G FOXM1 forkhead box M1 decreases expression EXP Fluorouracil results in decreased expression of FOXM1 mRNA CTD PMID:34151400 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXN3 forkhead box N3 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of FOXN3 protein
FOXN3 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr14:89,156,177...89,619,165
Ensembl chr14:89,124,871...89,619,149 		JBrowse link
G FOXO3 forkhead box O3 affects response to substance EXP FOXO3 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FPGS folylpolyglutamate synthase increases response to substance EXP FPGS protein results in increased susceptibility to Fluorouracil CTD PMID:15542523 NCBI chr 9:127,802,858...127,814,506
Ensembl chr 9:127,794,597...127,814,494 		JBrowse link
G FTLP3 ferritin light chain pseudogene 3 affects response to substance EXP FTLP3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:4,023,718...4,024,588
Ensembl chr20:4,023,917...4,024,444 		JBrowse link
G FUT1 fucosyltransferase 1 (H blood group) affects response to substance EXP FUT1 protein affects the susceptibility to Fluorouracil CTD PMID:15649251 NCBI chr19:48,748,011...48,755,358
Ensembl chr19:48,748,011...48,755,390 		JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 increases expression EXP Fluorouracil results in increased expression of FXYD3 mRNA CTD PMID:15152939 NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase affects response to substance EXP FYN protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G FZD2 frizzled class receptor 2 affects response to substance EXP FZD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:44,557,484...44,561,262
Ensembl chr17:44,557,484...44,561,262 		JBrowse link
G G0S2 G0/G1 switch 2 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of G0S2 protein
G0S2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 increases expression ISO Fluorouracil results in increased expression of GABRB3 protein CTD PMID:21296659 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,552...26,939,539 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression
decreases expression
affects response to substance
increases response to substance
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of GADD45A mRNA; Fluorouracil results in increased expression of GADD45A protein
Fluorouracil results in decreased expression of GADD45A mRNA
GADD45A protein affects the susceptibility to Fluorouracil
GADD45A protein results in increased susceptibility to Fluorouracil
GADD45A affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA]		 CTD PMID:15016801 PMID:15067352 PMID:15205334 PMID:16709241 PMID:16732331 More... NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta decreases response to substance
affects response to substance
multiple interactions		 EXP
ISO		 GADD45B protein results in decreased susceptibility to Fluorouracil
GADD45B protein affects the susceptibility to Fluorouracil
IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]		 CTD PMID:16732331 PMID:17711513 NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression ISO Fluorouracil results in increased expression of GADD45G mRNA CTD PMID:19272435 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555 		JBrowse link
G GAL galanin and GMAP prepropeptide decreases expression ISO Fluorouracil results in decreased expression of GAL protein CTD PMID:21296659 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175 		JBrowse link
G GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 affects response to substance EXP GALNT3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:165,747,588...165,794,692
Ensembl chr 2:165,747,588...165,846,201 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase increases expression
affects response to substance
multiple interactions		 EXP Fluorouracil results in increased expression of GAMT protein
GAMT protein affects the susceptibility to Fluorouracil
GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA]		 CTD PMID:15016801 PMID:15352031 PMID:16896004 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase affects splicing
decreases expression		 EXP
ISO		 Fluorouracil affects the splicing of GAPDH mRNA
Fluorouracil results in decreased expression of GAPDH protein		 CTD PMID:17169984 PMID:21296659 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression EXP Fluorouracil results in increased expression of GART mRNA CTD PMID:19219653 NCBI chr21:33,503,931...33,542,893
Ensembl chr21:33,503,931...33,543,491 		JBrowse link
G GAST gastrin decreases response to substance ISO GAST protein modified form results in decreased susceptibility to Fluorouracil CTD PMID:16618411 NCBI chr17:41,712,331...41,715,969
Ensembl chr17:41,712,331...41,715,969 		JBrowse link
G GATA2 GATA binding protein 2 multiple interactions EXP Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GATA4 GATA binding protein 4 affects expression ISO Fluorouracil affects the expression of GATA4 protein CTD PMID:21296659 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G GATA6 GATA binding protein 6 affects expression ISO Fluorouracil affects the expression of GATA6 protein CTD PMID:21296659 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit affects response to substance EXP GCLM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GCSH glycine cleavage system protein H multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA] CTD PMID:15016801 NCBI chr16:81,081,945...81,096,395
Ensembl chr16:81,081,945...81,096,395 		JBrowse link
G GDF1 growth differentiation factor 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA] CTD PMID:15016801 NCBI chr19:18,868,545...18,896,158
Ensembl chr19:18,868,545...18,896,158 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of GDF15 mRNA; Fluorouracil results in increased expression of GDF15 protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA]		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:24737281 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GDF3 growth differentiation factor 3 affects expression ISO Fluorouracil affects the expression of GDF3 protein CTD PMID:21296659 NCBI chr12:7,689,784...7,695,775
Ensembl chr12:7,689,784...7,695,775 		JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle affects expression EXP Fluorouracil affects the expression of GEM mRNA CTD PMID:15205334 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350 		JBrowse link
G GFAP glial fibrillary acidic protein increases expression ISO Fluorouracil results in increased expression of GFAP protein CTD PMID:21296659 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 multiple interactions EXP GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G GINS1 GINS complex subunit 1 increases response to substance ISO GINS1 gene mutant form results in increased susceptibility to Fluorouracil CTD PMID:18984863 NCBI chr20:25,407,673...25,448,563
Ensembl chr20:25,391,008...25,452,700 		JBrowse link
G GINS2 GINS complex subunit 2 affects expression EXP Fluorouracil affects the expression of GINS2 mRNA CTD PMID:16584549 NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073 		JBrowse link
G GJA1 gap junction protein alpha 1 affects response to substance ISO
EXP		 GJA1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 PMID:16531325 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJC1 gap junction protein gamma 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA] CTD PMID:15016801 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816 		JBrowse link
G GLA galactosidase alpha affects response to substance EXP GLA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:101,397,803...101,407,925
Ensembl chr  X:101,393,273...101,408,012 		JBrowse link
G GLI1 GLI family zinc finger 1 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of GLI1 mRNA
GLI1 protein inhibits the reaction [Fluorouracil affects the localization of PTCH1 protein]		 CTD PMID:18776995 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLIPR1 GLI pathogenesis related 1 increases expression EXP Fluorouracil results in increased expression of GLIPR1 mRNA CTD PMID:24737281 NCBI chr12:75,480,755...75,503,863
Ensembl chr12:75,480,753...75,503,863 		JBrowse link
G GNB2 G protein subunit beta 2 decreases expression EXP Fluorouracil results in decreased expression of GNB2 mRNA CTD PMID:16709241 NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174 		JBrowse link
G GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of GNE protein
GNE protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 9:36,214,441...36,276,978
Ensembl chr 9:36,214,441...36,277,042 		JBrowse link
G GOLGA8A golgin A8 family member A multiple interactions EXP GOLGA8A mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr15:34,379,068...34,437,808
Ensembl chr15:34,378,935...34,437,808 		JBrowse link
G GOLPH3 golgi phosphoprotein 3 increases response to substance EXP GOLPH3 protein results in increased susceptibility to Fluorouracil CTD PMID:38828452 NCBI chr 5:32,124,716...32,174,319
Ensembl chr 5:32,124,716...32,174,319 		JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta affects expression EXP Fluorouracil affects the expression of GP1BB mRNA CTD PMID:16584549 NCBI chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771 		JBrowse link
G GPR132 G protein-coupled receptor 132 increases expression EXP Fluorouracil results in increased expression of GPR132 mRNA CTD PMID:16584549 NCBI chr14:105,049,395...105,065,430
Ensembl chr14:105,049,395...105,065,445 		JBrowse link
G GPR137C G protein-coupled receptor 137C affects expression EXP Fluorouracil affects the expression of GPR137C mRNA CTD PMID:16584549 NCBI chr14:52,552,836...52,637,713
Ensembl chr14:52,552,836...52,637,713 		JBrowse link
G GPR35 G protein-coupled receptor 35 affects response to substance
increases expression		 EXP GPR35 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of GPR35 mRNA		 CTD PMID:15331170 NCBI chr 2:240,605,430...240,633,159
Ensembl chr 2:240,605,430...240,633,159 		JBrowse link
G GPR87 G protein-coupled receptor 87 increases expression EXP Fluorouracil results in increased expression of GPR87 mRNA CTD PMID:24737281 NCBI chr 3:151,294,086...151,316,820
Ensembl chr 3:151,294,086...151,316,820 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions
increases activity		 ISO Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]
Fluorouracil results in increased activity of GPT protein		 CTD PMID:27836789 PMID:29678497 PMID:31129132 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX1 glutathione peroxidase 1 increases expression
decreases activity
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of GPX1 mRNA
Fluorouracil results in decreased activity of GPX1 protein
TP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA]		 CTD PMID:17982676 PMID:29117755 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA] CTD PMID:15016801 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions
decreases expression		 ISO ferrostatin-1 inhibits the reaction [Fluorouracil results in decreased expression of GPX4 protein] CTD PMID:35101590 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GRAMD4 GRAM domain containing 4 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of GRAMD4 mRNA
TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA]		 CTD PMID:21127500 NCBI chr22:46,575,744...46,682,756
Ensembl chr22:46,576,012...46,679,790 		JBrowse link
G GRB7 growth factor receptor bound protein 7 increases expression ISO Fluorouracil results in increased expression of GRB7 protein CTD PMID:21296659 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291 		JBrowse link
G GRHL3 grainyhead like transcription factor 3 affects expression EXP Fluorouracil affects the expression of GRHL3 mRNA CTD PMID:16584549 NCBI chr 1:24,319,357...24,364,482
Ensembl chr 1:24,199,558...24,364,482 		JBrowse link
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Fluorouracil affects the expression of GRINA mRNA CTD PMID:16584549 NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415 		JBrowse link
G GSPT1 G1 to S phase transition 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA] CTD PMID:15016801 NCBI chr16:11,868,128...11,916,654
Ensembl chr16:11,868,128...11,916,082 		JBrowse link
G GSR glutathione-disulfide reductase decreases activity EXP Fluorouracil results in decreased activity of GSR protein CTD PMID:32752303 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 affects response to substance EXP GSTA4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA CTD PMID:32800223 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of GSTP1 mRNA
[Cisplatin co-treated with Fluorouracil] results in decreased expression of GSTP1 mRNA; GSTP1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; GSTP1 gene polymorphism results in decreased susceptibility to [Fluorouracil co-treated with Cisplatin]		 CTD PMID:15205334 PMID:15213713 PMID:15737843 PMID:16622263 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 increases expression EXP Fluorouracil results in increased expression of GSTT1 protein CTD PMID:15585135 PMID:16803524
G GTPBP4 GTP binding protein 4 affects response to substance EXP GTPBP4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:988,434...1,019,932
Ensembl chr10:988,434...1,019,932 		JBrowse link
G GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 decreases expression EXP Fluorouracil results in decreased expression of GUCY1B1 mRNA CTD PMID:19219653 NCBI chr 4:155,759,021...155,807,811
Ensembl chr 4:155,758,992...155,807,811 		JBrowse link
G GYG2 glycogenin 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of GYG2 mRNA] CTD PMID:15016801 NCBI chr  X:2,828,930...2,882,818
Ensembl chr  X:2,828,822...2,882,818 		JBrowse link
G H1-0 H1.0 linker histone affects expression ISO Fluorouracil affects the expression of H1F0 mRNA CTD PMID:20421339 NCBI chr22:37,805,229...37,807,432
Ensembl chr22:37,805,229...37,807,432 		JBrowse link
G H1-3 H1.3 linker histone, cluster member increases expression EXP Fluorouracil results in increased expression of H1-3 protein CTD PMID:15585135 NCBI chr 6:26,234,212...26,234,987
Ensembl chr 6:26,234,212...26,234,987 		JBrowse link
G H2AX H2A.X variant histone affects expression
multiple interactions
increases phosphorylation		 EXP Fluorouracil affects the expression of H2AX mRNA
[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased expression of H2AX protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]; TP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AX mRNA]
Fluorouracil results in increased phosphorylation of H2AX protein		 CTD PMID:15016801 PMID:16584549 PMID:25940438 PMID:26544897 PMID:34510228 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G H2BC12 H2B clustered histone 12 decreases expression
affects response to substance
increases expression		 EXP Fluorouracil results in decreased expression of H2BC12 mRNA
H2BC12 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of H2BC12 protein		 CTD PMID:15352031 PMID:16101138 PMID:16217747 NCBI chr 6:27,138,293...27,146,858
Ensembl chr 6:27,137,298...27,146,855 		JBrowse link
G H3-7 H3.7 histone (putative) decreases expression EXP Fluorouracil results in decreased expression of H3-7 mRNA CTD PMID:16101138 NCBI chr 1:143,902,386...143,905,977
Ensembl chr 1:143,894,544...143,905,977 		JBrowse link
G H4C14 H4 clustered histone 14 affects expression EXP Fluorouracil affects the expression of H4C14 mRNA CTD PMID:16584549 NCBI chr 1:149,832,657...149,833,052
Ensembl chr 1:149,832,657...149,839,767 		JBrowse link
G H4C2 H4 clustered histone 2 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of H4C2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of H4C2 mRNA]		 CTD PMID:15016801 PMID:17039268 NCBI chr 6:26,026,896...26,027,283
Ensembl chr 6:26,025,802...26,027,283 		JBrowse link
G H4C3 H4 clustered histone 3 decreases expression EXP Fluorouracil results in decreased expression of H4C3 mRNA CTD PMID:16510598 PMID:17039268 NCBI chr 6:26,103,933...26,104,337
Ensembl chr 6:26,103,933...26,104,337 		JBrowse link
G HACD1 3-hydroxyacyl-CoA dehydratase 1 affects response to substance EXP HACD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:17,589,032...17,617,374
Ensembl chr10:17,589,032...17,617,374 		JBrowse link
G HAND1 heart and neural crest derivatives expressed 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA] CTD PMID:15016801 NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227 		JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 increases expression EXP Fluorouracil results in increased expression of HAND2 mRNA CTD PMID:24737281 NCBI chr 4:173,526,091...173,530,229
Ensembl chr 4:173,524,969...173,530,229 		JBrowse link
G HAPLN2 hyaluronan and proteoglycan link protein 2 affects expression EXP Fluorouracil affects the expression of HAPLN2 mRNA CTD PMID:16584549 NCBI chr 1:156,601,504...156,625,725
Ensembl chr 1:156,619,331...156,625,725 		JBrowse link
G HBA1 hemoglobin subunit alpha 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA] CTD PMID:15016801 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522 		JBrowse link
G HBB hemoglobin subunit beta affects splicing EXP Fluorouracil affects the splicing of HBB mRNA CTD PMID:17169984 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395 		JBrowse link
G HBE1 hemoglobin subunit epsilon 1 affects response to substance
decreases expression		 EXP HBE1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of HBE1 protein		 CTD PMID:15352031 NCBI chr11:5,268,345...5,269,945
Ensembl chr11:5,268,345...5,505,652 		JBrowse link
G HBZ hemoglobin subunit zeta decreases expression ISO Fluorouracil results in decreased expression of HBZ protein CTD PMID:21296659 NCBI chr16:152,644...154,503
Ensembl chr16:142,728...154,503 		JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions ISO [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC1 protein] CTD PMID:25178657 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC2 histone deacetylase 2 multiple interactions
increases response to substance		 ISO
EXP		 [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC2 protein]
HDAC2 protein results in increased susceptibility to Fluorouracil		 CTD PMID:25178657 PMID:35608750 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC3 histone deacetylase 3 decreases expression ISO Fluorouracil results in decreased expression of HDAC3 mRNA CTD PMID:19272435 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849 		JBrowse link
G HDAC4 histone deacetylase 4 decreases expression EXP Fluorouracil results in decreased expression of HDAC4 mRNA CTD PMID:16557594 NCBI chr 2:239,048,168...239,401,649
NCBI chr 2:239,193,331...239,195,457
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HDAC7 histone deacetylase 7 decreases expression ISO Fluorouracil results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr12:47,782,722...47,821,344
Ensembl chr12:47,782,722...47,833,132 		JBrowse link
G HDAC9 histone deacetylase 9 increases expression EXP Fluorouracil results in increased expression of HDAC9 mRNA CTD PMID:24737281 NCBI chr 7:18,086,825...19,002,416
Ensembl chr 7:18,086,949...19,002,416 		JBrowse link
G HDGFL3 HDGF like 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA] CTD PMID:15016801 NCBI chr15:83,112,738...83,207,823
Ensembl chr15:83,112,738...83,207,875 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA] CTD PMID:15016801 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HES1 hes family bHLH transcription factor 1 increases activity EXP Fluorouracil results in increased activity of HES1 protein CTD PMID:19147571 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HGF hepatocyte growth factor increases expression EXP Fluorouracil results in increased expression of HGF mRNA CTD PMID:24737281 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HIC2 HIC ZBTB transcriptional repressor 2 affects response to substance EXP HIC2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:21,417,371...21,451,463
Ensembl chr22:21,417,371...21,451,463 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha affects localization
multiple interactions
increases expression
decreases expression
decreases uptake
affects response to substance
decreases response to substance		 EXP
ISO		 Fluorouracil affects the localization of HIF1A protein
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein]; Fluorouracil inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein]
Fluorouracil results in increased expression of HIF1A mRNA
Fluorouracil results in decreased expression of HIF1A mRNA; Fluorouracil results in decreased expression of HIF1A protein
HIF1A protein results in decreased uptake of Fluorouracil
HIF1A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased susceptibility to HIF1A protein; HIF1A results in decreased susceptibility to Fluorouracil
Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Cyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil]		 CTD PMID:16628086 PMID:17066447 PMID:17219956 PMID:27163855 PMID:34794354 More... NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HINT1 histidine triad nucleotide binding protein 1 increases expression EXP Fluorouracil results in increased expression of HINT1 protein CTD PMID:15585135 PMID:16803524 NCBI chr 5:131,159,027...131,165,256
Ensembl chr 5:131,155,383...131,224,468 		JBrowse link
G HK2 hexokinase 2 decreases expression
affects response to substance
multiple interactions		 EXP Fluorouracil results in decreased expression of HK2 protein
HK2 protein affects the susceptibility to Fluorouracil
HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]		 CTD PMID:16595493 PMID:18772588 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HLA-F major histocompatibility complex, class I, F increases expression EXP Fluorouracil results in increased expression of HLA-F mRNA CTD PMID:16101138 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G HLA-G major histocompatibility complex, class I, G increases expression EXP Fluorouracil results in increased expression of HLA-G mRNA CTD PMID:16101138 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G HM13 histocompatibility minor 13 affects expression EXP Fluorouracil affects the expression of HM13 mRNA CTD PMID:16584549 NCBI chr20:31,514,442...31,569,543
Ensembl chr20:31,514,428...31,577,923 		JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific affects response to substance EXP HMCES protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:129,278,832...129,306,186
Ensembl chr 3:129,278,828...129,306,186 		JBrowse link
G HMG20B high mobility group 20B decreases expression EXP Fluorouracil results in decreased expression of HMG20B mRNA CTD PMID:16709241 NCBI chr19:3,572,944...3,579,083
Ensembl chr19:3,572,777...3,579,088 		JBrowse link
G HMGB1 high mobility group box 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA] CTD PMID:15016801 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGN5 high mobility group nucleosome binding domain 5 increases expression EXP Fluorouracil results in increased expression of HMGN5 mRNA CTD PMID:16510598 NCBI chr  X:81,113,699...81,201,913
Ensembl chr  X:81,113,699...81,201,913 		JBrowse link
G HMMR hyaluronan mediated motility receptor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA] CTD PMID:15016801 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
affects expression		 ISO Fluorouracil results in increased expression of HMOX1
Fluorouracil affects the expression of HMOX1 mRNA		 CTD PMID:20722640 PMID:22954530 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF1A HNF1 homeobox A affects expression EXP Fluorouracil affects the expression of HNF1A mRNA CTD PMID:34151400 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha affects expression EXP Fluorouracil affects the expression of HNF4A mRNA CTD PMID:34151400 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of HNRNPA1 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA]		 CTD PMID:15016801 PMID:16101138 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA] CTD PMID:15016801 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529 		JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C increases expression EXP Fluorouracil results in increased expression of HNRNPC protein CTD PMID:15585135 PMID:16803524 NCBI chr14:21,209,147...21,269,442
Ensembl chr14:21,209,136...21,269,494 		JBrowse link
G HNRNPF heterogeneous nuclear ribonucleoprotein F multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA] CTD PMID:15016801 NCBI chr10:43,385,618...43,409,186
Ensembl chr10:43,385,617...43,409,186 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA] CTD PMID:15016801 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784 		JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA] CTD PMID:15016801 NCBI chr19:38,836,370...38,852,347
Ensembl chr19:38,836,370...38,852,347 		JBrowse link
G HOXA1 homeobox A1 decreases expression EXP Fluorouracil results in decreased expression of HOXA1 mRNA CTD PMID:24737281 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000 		JBrowse link
G HOXB3 homeobox B3 decreases expression EXP Fluorouracil results in decreased expression of HOXB3 mRNA CTD PMID:24737281 NCBI chr17:48,548,870...48,590,241
Ensembl chr17:48,548,870...48,604,912 		JBrowse link
G HOXC11 homeobox C11 affects expression
affects response to substance		 EXP Fluorouracil affects the expression of HOXC11 protein
HOXC11 protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 NCBI chr12:53,973,126...53,977,643
Ensembl chr12:53,973,126...53,977,643 		JBrowse link
G HOXD1 homeobox D1 decreases expression EXP Fluorouracil results in decreased expression of HOXD1 mRNA CTD PMID:24737281 NCBI chr 2:176,188,668...176,190,907
Ensembl chr 2:176,188,668...176,190,907 		JBrowse link
G HPX hemopexin multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA] CTD PMID:15016801 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G HRAS HRas proto-oncogene, GTPase increases expression EXP Fluorouracil results in increased expression of HRAS mRNA CTD PMID:16557594 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HS6ST2 heparan sulfate 6-O-sulfotransferase 2 decreases expression EXP Fluorouracil results in decreased expression of HS6ST2 mRNA CTD PMID:16510598 NCBI chr  X:132,626,015...132,961,370
Ensembl chr  X:132,626,015...132,961,395 		JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 affects expression EXP Fluorouracil affects the expression of HSD17B2 mRNA CTD PMID:16584549 NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of HSPA1B protein
HSPA1B protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of HSPA2 mRNA
HSPA2 protein affects the susceptibility to Fluorouracil		 CTD PMID:16101138 PMID:16217747 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of HSPA4 protein
HSPA4 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Fluorouracil results in decreased expression of HSPA5 mRNA; Fluorouracil results in decreased expression of HSPA5 protein CTD PMID:29879413 PMID:32535746 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 affects response to substance EXP HSPA8 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions
decreases response to substance		 EXP HSPB1 protein affects the susceptibility to [Cisplatin co-treated with Fluorouracil co-treated with Leucovorin]
HSPB1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:18949417 PMID:19088045 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G HSPB2 heat shock protein family B (small) member 2 increases phosphorylation
multiple interactions		 EXP Fluorouracil results in increased phosphorylation of HSPB2 protein
SB 203580 inhibits the reaction [Fluorouracil results in increased phosphorylation of HSPB2 protein]		 CTD PMID:18757417 NCBI chr11:111,912,734...111,914,093
Ensembl chr11:111,912,734...111,914,093 		JBrowse link
G HSPB8 heat shock protein family B (small) member 8 increases expression EXP Fluorouracil results in increased expression of HSPB8 mRNA CTD PMID:16557594 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855 		JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 increases expression EXP Fluorouracil results in increased expression of HSPE1 mRNA CTD PMID:15152939 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449 		JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 multiple interactions
increases response to substance		 EXP
ISO		 [Fluorouracil co-treated with irinotecan] results in increased expression of HTATIP2 mRNA
HTATIP2 protein results in increased susceptibility to Fluorouracil		 CTD PMID:16391804 PMID:16799960 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 affects expression EXP Fluorouracil affects the expression of HTR7 mRNA CTD PMID:16584549 NCBI chr10:90,740,823...90,858,039
Ensembl chr10:90,740,823...90,858,039 		JBrowse link
G HTRA1 HtrA serine peptidase 1 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of HTRA1 protein
HTRA1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G IAPP islet amyloid polypeptide decreases expression ISO Fluorouracil results in decreased expression of IAPP protein CTD PMID:21296659 NCBI chr12:21,354,959...21,379,980
Ensembl chr12:21,354,959...21,379,980 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of ID1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID1 mRNA]		 CTD PMID:16557594 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,573,014...31,606,515 		JBrowse link
G ID2 inhibitor of DNA binding 2 decreases expression
increases expression
multiple interactions
affects response to substance		 EXP
ISO		 Fluorouracil results in decreased expression of ID2 protein
Fluorouracil results in increased expression of ID2 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]
ID2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15016739 PMID:15352031 PMID:16557594 PMID:25178657 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G ID2B inhibitor of DNA binding 2B (pseudogene) affects response to substance
multiple interactions		 EXP ID2B protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of ID2B mRNA]		 CTD PMID:15016801 PMID:15352031 NCBI chr 3:62,123,426...62,124,718 JBrowse link
G ID3 inhibitor of DNA binding 3 increases expression EXP Fluorouracil results in increased expression of ID3 mRNA CTD PMID:15205334 PMID:16557594 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 affects response to substance EXP IDI1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IER5 immediate early response 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of IER5 mRNA] CTD PMID:15016801 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900 		JBrowse link
G IFI16 interferon gamma inducible protein 16 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of IFI16 mRNA] CTD PMID:15016801 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IFI27L2 interferon alpha inducible protein 27 like 2 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of IFI27L2 mRNA CTD PMID:16391804 NCBI chr14:94,127,781...94,129,604
Ensembl chr14:94,127,779...94,130,253 		JBrowse link
G IFI35 interferon induced protein 35 increases expression EXP Fluorouracil results in increased expression of IFI35 mRNA CTD PMID:16101138 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G IFI6 interferon alpha inducible protein 6 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of IFI6 mRNA
IFI6 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]		 CTD PMID:15685448 PMID:17039268 NCBI chr 1:27,666,064...27,672,192
Ensembl chr 1:27,666,064...27,672,212 		JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 increases expression EXP Fluorouracil results in increased expression of IFIT1 mRNA CTD PMID:17039268 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487 		JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 increases expression EXP Fluorouracil results in increased expression of IFIT2 mRNA CTD PMID:16101138 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 increases expression
decreases expression		 EXP
ISO		 Fluorouracil results in increased expression of IFITM1 mRNA
Fluorouracil results in decreased expression of IFITM1 protein		 CTD PMID:16101138 PMID:16510598 PMID:17039268 PMID:21296659 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
G IFITM2 interferon induced transmembrane protein 2 increases expression ISO Fluorouracil results in increased expression of IFITM2 protein CTD PMID:21296659 NCBI chr11:307,816...309,395
Ensembl chr11:303,655...309,397 		JBrowse link
G IFITM4P interferon induced transmembrane protein 4 pseudogene increases expression EXP Fluorouracil results in increased expression of IFITM4P mRNA CTD PMID:16101138 NCBI chr 6:29,750,807...29,751,148
Ensembl chr 6:29,750,729...29,751,148 		JBrowse link
G IFNA1 interferon alpha 1 multiple interactions
increases abundance
increases response to substance		 EXP
ISO		 [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein]; ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]; Fluorouracil promotes the reaction [IFNA1 protein results in increased expression of TP53AIP1 mRNA]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; IFNA1 protein promotes the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]; VEGFA protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of RGS5 mRNA]
IFNA1 protein results in increased abundance of Fluorouracil
IFNA1 protein results in increased susceptibility to Fluorouracil		 CTD PMID:16101138 PMID:16568373 PMID:17016659 PMID:17045692 PMID:17786339 More... NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 increases expression EXP Fluorouracil results in increased expression of IFNAR1 mRNA; Fluorouracil results in increased expression of IFNAR1 protein CTD PMID:17088986 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 increases expression EXP Fluorouracil results in increased expression of IFNAR2 mRNA; Fluorouracil results in increased expression of IFNAR2 protein CTD PMID:16101138 PMID:17088986 NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,205,282...33,265,675 		JBrowse link
G IFNB1 interferon beta 1 multiple interactions
increases response to substance		 EXP [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein
IFNB1 protein results in increased susceptibility to Fluorouracil		 CTD PMID:15937643 PMID:16101138 PMID:18608205 PMID:18695887 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNG interferon gamma multiple interactions
decreases expression
increases abundance		 EXP
ISO		 [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to Fluorouracil; Fluorouracil promotes the reaction [IL18 protein modified form results in increased expression of IFNG protein]; IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]
Fluorouracil results in decreased expression of IFNG protein
LCS101 inhibits the reaction [Fluorouracil results in decreased expression of IFNG protein]
IFNG protein results in increased abundance of Fluorouracil		 CTD PMID:15162350 PMID:15301717 PMID:15754409 PMID:16568373 PMID:17711513 More... NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 increases expression
multiple interactions		 ISO
EXP		 Fluorouracil results in increased expression of IGF1 mRNA
[Fluorouracil co-treated with IGF1 protein] results in increased expression of MT2A mRNA; IGF1 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; IGF1 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]		 CTD PMID:16888818 PMID:28507149 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of IGF1R protein CTD PMID:17918158 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 increases expression ISO Fluorouracil results in increased expression of IGFBP2 protein CTD PMID:21296659 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 multiple interactions EXP IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 decreases expression EXP Fluorouracil results in decreased expression of IGFBP5 mRNA CTD PMID:16557594 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of IGFBP6 protein
IGFBP6 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345 		JBrowse link
G IHH Indian hedgehog signaling molecule decreases expression EXP Fluorouracil results in decreased expression of IHH mRNA; Fluorouracil results in decreased expression of IHH protein CTD PMID:25190613 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921 		JBrowse link
G IKBIP IKBKB interacting protein increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of IKBIP mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of IKBIP mRNA]		 CTD PMID:17982676 NCBI chr12:98,613,404...98,644,788
Ensembl chr12:98,613,405...98,645,113 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta decreases expression EXP Fluorouracil results in decreased expression of IKBKB protein CTD PMID:30177839 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression		 ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein
Fluorouracil results in decreased expression of IL10 protein
[Thymol co-treated with Fluorouracil] results in increased expression of IL10 protein		 CTD PMID:31651976 PMID:34665902 PMID:38078205 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B decreases expression ISO Fluorouracil results in decreased expression of IL12B protein CTD PMID:15754409 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL18 interleukin 18 multiple interactions
affects expression		 EXP
ISO		 [Fluorouracil co-treated with Irinotecan] results in decreased expression of IL18 mRNA; Fluorouracil promotes the reaction [IL18 protein modified form results in increased expression of IFNG protein]; Fluorouracil results in increased cleavage of and results in increased secretion of IL18 protein
Fluorouracil affects the expression of IL18 mRNA		 CTD PMID:15162350 PMID:16391804 PMID:20421339 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein CTD PMID:31651976 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
increases secretion		 ISO
EXP		 Fluorouracil results in increased expression of IL1B mRNA; Fluorouracil results in increased expression of IL1B protein
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of IL1B protein]
Fluorouracil results in increased secretion of IL1B protein
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; Hydroxychloroquine inhibits the reaction [Fluorouracil results in increased secretion of IL1B protein]
IL1B promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin]		 CTD PMID:16820919 PMID:18523641 PMID:18535404 PMID:19528421 PMID:20844880 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist multiple interactions ISO IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein] CTD PMID:20844880 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha affects response to substance EXP IL27RA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL3 interleukin 3 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases secretion
increases expression		 EXP
ISO		 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of IL6 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased secretion of IL6 protein]; [Fluorouracil co-treated with IL6 protein] results in increased expression of MT2A mRNA; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Fluorouracil results in increased expression of IL6 mRNA]; IL6 promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin]; IL6 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; IL6 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; IL6 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; IL6 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; pyrazolanthrone inhibits the reaction [Fluorouracil results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of IL6 mRNA]
Fluorouracil promotes the reaction [Valsartan results in decreased secretion of IL6 protein]
Fluorouracil results in increased expression of IL6 protein
Fluorouracil inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of IL6 protein]; Thymol inhibits the reaction [Fluorouracil results in increased expression of IL6 protein]		 CTD PMID:16820919 PMID:18344199 PMID:18523641 PMID:25824412 PMID:28507149 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 affects expression ISO Fluorouracil affects the expression of IL7 mRNA CTD PMID:18344199 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IMPA2 inositol monophosphatase 2 increases expression EXP Fluorouracil results in increased expression of IMPA2 mRNA CTD PMID:16510598 NCBI chr18:11,981,507...12,030,877
Ensembl chr18:11,981,025...12,030,877 		JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 increases expression EXP Fluorouracil results in increased expression of IMPDH2 mRNA CTD PMID:19219653 NCBI chr 3:49,024,325...49,029,398
Ensembl chr 3:49,024,325...49,029,447 		JBrowse link
G INKA2 inka box actin regulator 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of INKA2 mRNA] CTD PMID:15016801 NCBI chr 1:111,722,064...111,755,797
Ensembl chr 1:111,680,630...111,755,824 		JBrowse link
G INPP5E inositol polyphosphate-5-phosphatase E multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of INPP5E mRNA] CTD PMID:15016801 NCBI chr 9:136,428,619...136,439,845
Ensembl chr 9:136,428,619...136,439,845 		JBrowse link
G INS insulin decreases expression ISO Fluorouracil results in decreased expression of INS2 protein CTD PMID:21296659 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INSIG1 insulin induced gene 1 increases expression EXP Fluorouracil results in increased expression of INSIG1 mRNA CTD PMID:17039268 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of IQGAP2 mRNA] CTD PMID:15016801 NCBI chr 5:76,403,285...76,708,132
Ensembl chr 5:76,403,285...76,708,132 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of IRAK1 mRNA
IRAK1 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IREB2 iron responsive element binding protein 2 increases expression EXP Fluorouracil results in increased expression of IREB2 mRNA CTD PMID:16584549 NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453 		JBrowse link
G IRF9 interferon regulatory factor 9 increases expression EXP Fluorouracil results in increased expression of IRF9 mRNA CTD PMID:16101138 PMID:17039268 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043 		JBrowse link
G IRGM immunity related GTPase M affects response to substance ISO IRGM1 protein affects the susceptibility to Fluorouracil CTD PMID:18371424 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier increases expression EXP Fluorouracil results in increased expression of ISG15 mRNA CTD PMID:16101138 PMID:16557594 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G ISL1 ISL LIM homeobox 1 decreases expression ISO Fluorouracil results in decreased expression of ISL1 protein CTD PMID:21296659 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730 		JBrowse link
G ITGAV integrin subunit alpha V affects response to substance EXP ITGAV protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITGB2 integrin subunit beta 2 decreases expression EXP Fluorouracil results in decreased expression of ITGB2 CTD PMID:15485462 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP Fluorouracil results in decreased expression of ITGB4 mRNA CTD PMID:15205334 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ITPR1 mRNA] CTD PMID:15016801 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G ITSN1 intersectin 1 affects response to substance EXP ITSN1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr21:33,642,501...33,899,861
Ensembl chr21:33,642,400...33,899,861 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 increases expression EXP Fluorouracil results in increased expression of JAG1 mRNA CTD PMID:16510598 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JMJD4 jumonji domain containing 4 decreases expression EXP Fluorouracil results in decreased expression of JMJD4 mRNA CTD PMID:34151400 NCBI chr 1:227,731,191...227,735,302
Ensembl chr 1:227,730,425...227,735,411 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit affects expression
increases expression		 EXP Fluorouracil affects the expression of JUN mRNA
Fluorouracil results in increased expression of JUN mRNA		 CTD PMID:15205334 PMID:16557594 PMID:17355264 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of JUNB mRNA
JUNB results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]		 CTD PMID:16557594 PMID:18678097 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 multiple interactions EXP KANSL1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr17:46,029,916...46,225,367
Ensembl chr17:46,029,916...46,225,389 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 increases response to substance EXP KCNA5 protein results in increased susceptibility to Fluorouracil CTD PMID:17428690 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of KCNQ2 mRNA] CTD PMID:15016801 NCBI chr20:63,400,208...63,472,655
Ensembl chr20:63,400,208...63,472,677 		JBrowse link
G KCTD12 potassium channel tetramerization domain containing 12 decreases expression EXP Fluorouracil results in decreased expression of KCTD12 mRNA CTD PMID:17039268 NCBI chr13:76,880,175...76,886,405
Ensembl chr13:76,880,175...76,886,405 		JBrowse link
G KDM4B lysine demethylase 4B multiple interactions
affects expression		 EXP
ISO		 KDM4B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fluorouracil affects the expression of KDM4B mRNA		 CTD PMID:16896004 PMID:20421339 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,611 		JBrowse link
G KDM5A lysine demethylase 5A decreases expression EXP Fluorouracil results in decreased expression of KDM5A mRNA CTD PMID:16557594 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KDR kinase insert domain receptor increases expression ISO Fluorouracil results in increased expression of KDR mRNA CTD PMID:26272751 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 affects response to substance EXP KEAP1 protein affects the susceptibility to Fluorouracil CTD PMID:18692501 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KHK ketohexokinase affects response to substance
increases expression		 EXP KHK protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of KHK protein		 CTD PMID:15352031 NCBI chr 2:27,086,772...27,100,762
Ensembl chr 2:27,086,772...27,100,762 		JBrowse link
G KIAA0040 KIAA0040 increases expression EXP Fluorouracil results in increased expression of KIAA0040 mRNA CTD PMID:16510598 NCBI chr 1:175,156,986...175,192,987
Ensembl chr 1:175,156,986...175,192,999 		JBrowse link
G KIF14 kinesin family member 14 decreases expression EXP Fluorouracil results in decreased expression of KIF14 mRNA CTD PMID:34151400 NCBI chr 1:200,551,497...200,620,751
Ensembl chr 1:200,551,497...200,620,751 		JBrowse link
G KIF15 kinesin family member 15 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF15 mRNA] CTD PMID:15016801 NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376 		JBrowse link
G KIF23 kinesin family member 23 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF23 mRNA] CTD PMID:15016801 NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427 		JBrowse link
G KIF26B kinesin family member 26B decreases expression EXP Fluorouracil results in decreased expression of KIF26B mRNA CTD PMID:34151400 NCBI chr 1:245,154,985...245,709,432
Ensembl chr 1:245,154,985...245,709,432 		JBrowse link
G KIF2C kinesin family member 2C affects response to substance EXP KIF2C protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767 		JBrowse link
G KIF3A kinesin family member 3A multiple interactions EXP KIF3A mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:132,688,812...132,737,546
Ensembl chr 5:132,692,628...132,737,638 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase affects response to substance
decreases expression		 ISO KIT protein mutant form affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of KIT protein		 CTD PMID:19100679 PMID:21296659 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G KITLG KIT ligand increases expression EXP Fluorouracil results in increased expression of KITLG mRNA CTD PMID:19098008 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KLF4 KLF transcription factor 4 increases expression
decreases response to substance		 EXP Fluorouracil results in increased expression of KLF4 mRNA
KLF4 results in decreased susceptibility to Fluorouracil		 CTD PMID:16557594 PMID:17039268 PMID:21833590 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KLF5 KLF transcription factor 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of KLF5 mRNA] CTD PMID:15016801 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KLF6 KLF transcription factor 6 decreases expression EXP Fluorouracil results in decreased expression of KLF6 mRNA CTD PMID:15205334 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281 		JBrowse link
G KLHL24 kelch like family member 24 increases expression EXP Fluorouracil results in increased expression of KLHL24 mRNA CTD PMID:16510598 NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519 		JBrowse link
G KLHL7 kelch like family member 7 affects response to substance EXP KLHL7 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:23,105,785...23,177,914
Ensembl chr 7:23,105,758...23,177,914 		JBrowse link
G KLHL9 kelch like family member 9 affects response to substance EXP KLHL9 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:21,329,665...21,335,404
Ensembl chr 9:21,320,024...21,335,404 		JBrowse link
G KLK15 kallikrein related peptidase 15 affects expression EXP Fluorouracil affects the expression of KLK15 mRNA CTD PMID:16584549 NCBI chr19:50,825,289...50,833,574
Ensembl chr19:50,825,289...50,837,213 		JBrowse link
G KLK6 kallikrein related peptidase 6 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of KLK6 protein
KLK6 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:50,958,631...50,969,591
Ensembl chr19:50,958,631...50,969,673 		JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) affects response to substance ISO KMT2E protein affects the susceptibility to Fluorouracil CTD PMID:18818388 NCBI chr 7:105,014,205...105,115,019
Ensembl chr 7:104,940,943...105,115,019 		JBrowse link
G KNG1 kininogen 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of KNG1 mRNA CTD PMID:16391804 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G KPNA2 karyopherin subunit alpha 2 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of KPNA2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of KPNA2 mRNA]		 CTD PMID:15016801 PMID:17374387 NCBI chr17:68,035,735...68,046,854
Ensembl chr17:68,035,636...68,047,364 		JBrowse link
G KPNA3 karyopherin subunit alpha 3 decreases expression EXP Fluorouracil results in decreased expression of KPNA3 mRNA CTD PMID:16709241 NCBI chr13:49,699,320...49,792,682
Ensembl chr13:49,699,320...49,792,682 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of KRAS protein
Fluorouracil results in increased expression of KRAS mRNA mutant form		 CTD PMID:15585135 PMID:16803524 PMID:38423379 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT1 keratin 1 affects expression ISO Fluorouracil affects the expression of KRT1 protein CTD PMID:21296659 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407 		JBrowse link
G KRT16 keratin 16 increases expression EXP Fluorouracil results in increased expression of KRT16 mRNA CTD PMID:19528421 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G KRT17 keratin 17 affects expression EXP Fluorouracil affects the expression of KRT17 mRNA CTD PMID:16584549 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842 		JBrowse link
G KRT18 keratin 18 multiple interactions
affects expression		 EXP [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of KRT18 protein
Fluorouracil affects the expression of KRT18 mRNA		 CTD PMID:15754201 PMID:34151400 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT5 keratin 5 affects response to substance
decreases expression		 EXP KRT5 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of KRT5 protein		 CTD PMID:15352031 NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530 		JBrowse link
G KRT6A keratin 6A affects expression EXP Fluorouracil affects the expression of KRT6A mRNA CTD PMID:16584549 NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257 		JBrowse link
G KRT86 keratin 86 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of KRT86 protein
KRT86 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr12:52,274,645...52,309,163
Ensembl chr12:52,249,300...52,309,163 		JBrowse link
G L1CAM L1 cell adhesion molecule decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of L1CAM protein
L1CAM protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173 		JBrowse link
G L1TD1 LINE1 type transposase domain containing 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of L1TD1 mRNA] CTD PMID:15016801 NCBI chr 1:62,194,849...62,212,328
Ensembl chr 1:62,194,790...62,235,060 		JBrowse link
G LAMA1 laminin subunit alpha 1 decreases expression ISO Fluorouracil results in decreased expression of LAMA1 protein CTD PMID:21296659 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797 		JBrowse link
G LAMB1 laminin subunit beta 1 decreases expression ISO Fluorouracil results in decreased expression of LAMB1 protein CTD PMID:21296659 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LAMC1 laminin subunit gamma 1 affects response to substance
decreases expression		 EXP
ISO		 LAMC1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of LAMC1 protein		 CTD PMID:16217747 PMID:21296659 NCBI chr 1:183,023,420...183,145,592
Ensembl chr 1:183,023,420...183,145,592 		JBrowse link
G LARP4B La ribonucleoprotein 4B affects response to substance EXP LARP4B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:806,914...988,341
Ensembl chr10:806,933...931,821 		JBrowse link
G LASP1 LIM and SH3 protein 1 affects response to substance EXP LASP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:38,870,058...38,921,770
Ensembl chr17:38,869,859...38,921,770 		JBrowse link
G LCMT2 leucine carboxyl methyltransferase 2 multiple interactions
increases response to substance		 ISO LCMT2 results in increased susceptibility to [pyrrolidine dithiocarbamic acid co-treated with Fluorouracil]
LCMT2 results in increased susceptibility to Fluorouracil		 CTD PMID:9359698 NCBI chr15:43,323,649...43,330,573
Ensembl chr15:43,323,649...43,330,582 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of LDHA mRNA] CTD PMID:15016801 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LDHB lactate dehydrogenase B affects response to substance EXP LDHB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857 		JBrowse link
G LEFTY1 left-right determination factor 1 decreases expression ISO Fluorouracil results in decreased expression of LEFTY1 protein CTD PMID:21296659 NCBI chr 1:225,886,282...225,889,146
Ensembl chr 1:225,886,282...225,911,382 		JBrowse link
G LEFTY2 left-right determination factor 2 decreases expression ISO
EXP		 Fluorouracil results in decreased expression of LEFTY2 protein
Fluorouracil results in decreased expression of LEFTY2 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr 1:225,936,603...225,941,220
Ensembl chr 1:225,936,598...225,941,383 		JBrowse link
G LGALS3 galectin 3 affects response to substance
multiple interactions
decreases response to substance		 EXP
ISO		 LGALS3 protein affects the susceptibility to Fluorouracil
5-fluorouracil inhibits the reaction [N-methyl-N-nitrosourea increases expression of Lgals3 protein in serum]
LGALS3 protein mutant form results in decreased susceptibility to Fluorouracil		 CTD
RGD		 PMID:16217747 PMID:21750908 PMID:28032729 RGD:150530464 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LGALS3BP galectin 3 binding protein affects response to substance EXP LGALS3BP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:78,971,255...78,979,923
Ensembl chr17:78,971,238...78,979,947 		JBrowse link
G LGALS7 galectin 7 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of LGALS7 protein
LGALS7 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754 		JBrowse link
G LGALS8 galectin 8 multiple interactions EXP LGALS8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 1:236,518,214...236,552,981
Ensembl chr 1:236,518,000...236,552,981 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 affects expression ISO Fluorouracil affects the expression of LGR4 mRNA CTD PMID:20421339 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 decreases expression EXP Fluorouracil results in decreased expression of LGR5 mRNA CTD PMID:24737281 NCBI chr12:71,439,129...71,586,310
Ensembl chr12:71,439,798...71,586,310 		JBrowse link
G LHX1 LIM homeobox 1 decreases expression EXP Fluorouracil results in decreased expression of LHX1 mRNA CTD PMID:24737281 NCBI chr17:36,936,785...36,944,612
Ensembl chr17:36,936,785...36,944,612 		JBrowse link
G LIFR LIF receptor subunit alpha decreases expression ISO Fluorouracil results in decreased expression of LIFR protein CTD PMID:21296659 NCBI chr 5:38,474,668...38,608,403
Ensembl chr 5:38,474,668...38,608,354 		JBrowse link
G LIG1 DNA ligase 1 affects response to substance EXP LIG1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr19:48,115,445...48,170,344
Ensembl chr19:48,115,445...48,170,603 		JBrowse link
G LIMK1 LIM domain kinase 1 affects expression EXP Fluorouracil affects the expression of LIMK1 mRNA CTD PMID:34151400 NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525 		JBrowse link
G LIMK2 LIM domain kinase 2 affects response to substance EXP LIMK2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:31,212,298...31,280,080
Ensembl chr22:31,212,239...31,280,080 		JBrowse link
G LIN28A lin-28 homolog A increases expression ISO Fluorouracil results in increased expression of LIN28A protein CTD PMID:21296659 NCBI chr 1:26,410,817...26,429,728
Ensembl chr 1:26,410,817...26,429,728 		JBrowse link
G LIPH lipase H decreases expression EXP Fluorouracil results in decreased expression of LIPH mRNA CTD PMID:16709241 NCBI chr 3:185,506,262...185,552,588
Ensembl chr 3:185,506,262...185,552,588 		JBrowse link
G LMF1 lipase maturation factor 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of LMF1 mRNA CTD PMID:16391804 NCBI chr16:853,634...981,613
Ensembl chr16:853,634...981,318 		JBrowse link
G LMNA lamin A/C increases cleavage EXP Fluorouracil results in increased cleavage of LMNA protein CTD PMID:18497562 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,572...156,140,081 		JBrowse link
G LMNB1 lamin B1 affects response to substance
decreases expression		 EXP LMNB1 affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of LMNB1 mRNA		 CTD PMID:15067352 PMID:34151400 NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020 		JBrowse link
G LMNB2 lamin B2 decreases expression EXP Fluorouracil results in decreased expression of LMNB2 mRNA CTD PMID:34151400 NCBI chr19:2,428,166...2,456,959
Ensembl chr19:2,427,638...2,456,959 		JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 decreases expression EXP Fluorouracil results in decreased expression of LPAR6 mRNA CTD PMID:17039268 NCBI chr13:48,389,571...48,444,669
Ensembl chr13:48,389,567...48,444,704 		JBrowse link
G LPO lactoperoxidase decreases expression EXP Fluorouracil results in decreased expression of LPO mRNA CTD PMID:34748853 NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518 		JBrowse link
G LPXN leupaxin affects response to substance EXP LPXN protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr11:58,526,871...58,578,891
Ensembl chr11:58,526,871...58,578,220 		JBrowse link
G LRATD1 LRAT domain containing 1 increases expression EXP Fluorouracil results in increased expression of LRATD1 mRNA CTD PMID:24737281 NCBI chr 2:14,632,717...14,651,916
Ensembl chr 2:14,632,700...14,650,814 		JBrowse link
G LRBA LPS responsive beige-like anchor protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of LRBA mRNA] CTD PMID:15016801 NCBI chr 4:150,264,435...151,015,727
Ensembl chr 4:150,264,435...151,015,727 		JBrowse link
G LRP8 LDL receptor related protein 8 decreases expression EXP Fluorouracil results in decreased expression of LRP8 mRNA CTD PMID:16101138 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469 		JBrowse link
G LSS lanosterol synthase affects response to substance EXP LSS protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G LXN latexin affects response to substance EXP LXN protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:158,666,414...158,672,648
Ensembl chr 3:158,645,822...158,672,648 		JBrowse link
G LY6G6C lymphocyte antigen 6 family member G6C affects response to substance EXP LY6G6C protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,718,648...31,721,746
Ensembl chr 6:31,718,648...31,721,746 		JBrowse link
G LY6G6D lymphocyte antigen 6 family member G6D affects response to substance EXP LY6G6D protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,715,348...31,717,919
Ensembl chr 6:31,715,348...31,717,919 		JBrowse link
G LYPLA1 lysophospholipase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of LYPLA1 mRNA] CTD PMID:15016801 NCBI chr 8:54,042,987...54,101,947
Ensembl chr 8:54,046,367...54,102,017 		JBrowse link
G M6PR mannose-6-phosphate receptor, cation dependent increases expression EXP Fluorouracil results in increased expression of M6PR protein CTD PMID:15585135 NCBI chr12:8,940,361...8,949,645
Ensembl chr12:8,940,361...8,949,761 		JBrowse link
G MACF1 microtubule actin crosslinking factor 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MACF1 mRNA] CTD PMID:15016801 NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 affects expression
decreases expression		 EXP
ISO		 Fluorouracil affects the expression of MAD2L1 mRNA
Fluorouracil results in decreased expression of MAD2L1 mRNA		 CTD PMID:16557594 PMID:17039268 PMID:19272435 NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 decreases expression EXP Fluorouracil results in decreased expression of MAD2L2 protein CTD PMID:16803524 NCBI chr 1:11,674,480...11,691,830
Ensembl chr 1:11,657,230...11,691,811 		JBrowse link
G MADD MAP kinase activating death domain affects expression EXP Fluorouracil affects the expression of MADD mRNA CTD PMID:34151400 NCBI chr11:47,269,188...47,330,031
Ensembl chr11:47,269,161...47,330,031 		JBrowse link
G MAF MAF bZIP transcription factor increases expression EXP Fluorouracil results in increased expression of MAF mRNA CTD PMID:16557594 NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737 		JBrowse link
G MAFF MAF bZIP transcription factor F affects response to substance EXP MAFF protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507 		JBrowse link
G MAGEA12 MAGE family member A12 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MAGEA12 protein
MAGEA12 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr  X:152,733,757...152,737,669
Ensembl chr  X:152,733,757...152,737,669 		JBrowse link
G MAGEA2 MAGE family member A2 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MAGEA2 protein
MAGEA2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr  X:152,749,863...152,753,884
Ensembl chr  X:152,714,586...152,718,607
Ensembl chr  X:152,714,586...152,718,607 		JBrowse link
G MAGEA4 MAGE family member A4 affects response to substance EXP MAGEA4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:151,912,474...151,925,170
Ensembl chr  X:151,912,495...151,925,171 		JBrowse link
G MAGEA6 MAGE family member A6 affects response to substance
decreases expression		 EXP MAGEA6 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of MAGEA6 protein		 CTD PMID:15352031 NCBI chr  X:152,766,136...152,769,689
Ensembl chr  X:152,766,136...152,769,716 		JBrowse link
G MAGEB2 MAGE family member B2 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MAGEB2 protein
MAGEB2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr  X:30,215,563...30,220,089
Ensembl chr  X:30,215,563...30,220,089 		JBrowse link
G MAGED1 MAGE family member D1 affects response to substance EXP MAGED1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 PMID:16217747 NCBI chr  X:51,803,076...51,902,354
Ensembl chr  X:51,803,007...51,902,354 		JBrowse link
G MAGED4B MAGE family member D4B affects response to substance EXP MAGED4B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:52,061,827...52,069,272
Ensembl chr  X:52,061,827...52,069,219 		JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of MALAT1 mRNA
MALAT1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]		 CTD PMID:16510598 PMID:18927307 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073 		JBrowse link
G MALT1 MALT1 paracaspase increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of MALT1 mRNA
MALT1 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MAMDC2 MAM domain containing 2 increases expression EXP Fluorouracil results in increased expression of MAMDC2 mRNA CTD PMID:16510598 NCBI chr 9:70,043,581...70,226,972
Ensembl chr 9:70,043,848...70,226,972 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 increases expression EXP Fluorouracil results in increased expression of MAML2 mRNA CTD PMID:16510598 NCBI chr11:95,976,598...96,343,195
Ensembl chr11:95,976,598...96,343,195 		JBrowse link
G MAN1A1 mannosidase alpha class 1A member 1 increases expression EXP Fluorouracil results in increased expression of MAN1A1 mRNA CTD PMID:16510598 NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761 		JBrowse link
G MANEA mannosidase endo-alpha affects expression ISO Fluorouracil affects the expression of MANEA mRNA CTD PMID:20421339 NCBI chr 6:95,577,535...95,609,452
Ensembl chr 6:95,577,485...95,609,470 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta affects response to substance EXP MAP1LC3B protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAP2 microtubule associated protein 2 increases expression EXP Fluorouracil results in increased expression of MAP2 mRNA CTD PMID:16510598 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions EXP [U 0126 results in decreased activity of MAP2K1 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]; MAP2K1 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 multiple interactions EXP [U 0126 results in decreased activity of MAP2K2 protein] results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]; MAP2K2 protein results in decreased susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21444628 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 decreases expression EXP 5-fluorouracil decreases expression of MAP2K7 protein in tongue squamous carcinoma cells RGD PMID:34411913 RGD:155630595 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 affects expression EXP Fluorouracil affects the expression of MAP3K1 mRNA CTD PMID:34151400 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 affects expression EXP Fluorouracil affects the expression of MAP3K20 mRNA CTD PMID:16584549 NCBI chr 2:173,075,517...173,268,015
Ensembl chr 2:173,075,435...173,268,015 		JBrowse link
G MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MAP4K5 mRNA] CTD PMID:15016801 NCBI chr14:50,418,521...50,561,126
Ensembl chr14:50,418,501...50,561,126 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation		 EXP Fluorouracil inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK1 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of MAPK1 protein; Nicotine inhibits the reaction [Fluorouracil results in increased phosphorylation of MAPK1 protein]
Fluorouracil results in decreased phosphorylation of MAPK1 protein		 CTD PMID:21444628 PMID:24095863 PMID:37625625 PMID:39334374 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK13 mitogen-activated protein kinase 13 increases expression EXP Fluorouracil results in increased expression of MAPK13 protein CTD PMID:15585135 PMID:16803524 NCBI chr 6:36,130,513...36,144,521
Ensembl chr 6:36,127,809...36,144,524 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation		 EXP Fluorouracil inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK3 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of MAPK3 protein; Nicotine inhibits the reaction [Fluorouracil results in increased phosphorylation of MAPK3 protein]
Fluorouracil results in decreased phosphorylation of MAPK3 protein		 CTD PMID:21444628 PMID:24095863 PMID:37625625 PMID:39334374 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK7 mitogen-activated protein kinase 7 multiple interactions
decreases response to substance		 EXP [BIX 02188 results in decreased activity of MAPK7] which results in increased susceptibility to Fluorouracil
MAPK7 results in decreased susceptibility to Fluorouracil		 CTD PMID:22008504 NCBI chr17:19,377,750...19,383,544
Ensembl chr17:19,377,721...19,383,544 		JBrowse link
G MAPKAP1 MAPK associated protein 1 increases expression EXP Fluorouracil results in increased expression of MAPKAP1 mRNA CTD PMID:16557594 NCBI chr 9:125,437,394...125,707,208
Ensembl chr 9:125,437,393...125,707,234 		JBrowse link
G MAPT microtubule associated protein tau multiple interactions EXP MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MARCKS mRNA
MARCKS protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:17039268 NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475 		JBrowse link
G MARS1 methionyl-tRNA synthetase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MARS1 mRNA] CTD PMID:15016801 NCBI chr12:57,488,068...57,516,652
Ensembl chr12:57,475,445...57,517,569 		JBrowse link
G MAST4 microtubule associated serine/threonine kinase family member 4 increases expression EXP Fluorouracil results in increased expression of MAST4 mRNA CTD PMID:16510598 NCBI chr 5:66,596,393...67,169,593
Ensembl chr 5:66,596,380...67,169,593 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase increases metabolic processing ISO MBD4 protein results in increased metabolism of Fluorouracil CTD PMID:16885370 NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179 		JBrowse link
G MBNL1 muscleblind like splicing regulator 1 decreases expression EXP Fluorouracil results in decreased expression of MBNL1 mRNA CTD PMID:16709241 NCBI chr 3:152,243,632...152,465,780
Ensembl chr 3:152,243,828...152,465,780 		JBrowse link
G MBP myelin basic protein decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of MBP mRNA; Fluorouracil results in decreased expression of MBP protein
[HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]		 CTD PMID:25178657 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683 		JBrowse link
G MCCC2 methylcrotonyl-CoA carboxylase subunit 2 multiple interactions EXP MCCC2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr 5:71,587,340...71,658,706
Ensembl chr 5:71,579,531...71,658,706 		JBrowse link
G MCF2 MCF.2 cell line derived transforming sequence increases expression EXP Fluorouracil results in increased expression of MCF2 mRNA CTD PMID:24737281 NCBI chr  X:139,581,770...139,708,167
Ensembl chr  X:139,581,770...139,708,216 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression
decreases expression
multiple interactions
decreases response to substance		 EXP
ISO		 Fluorouracil affects the expression of MCL1 protein
Fluorouracil results in decreased expression of MCL1 mRNA
Apigenin promotes the reaction [Fluorouracil results in decreased expression of MCL1 mRNA]; Fluorouracil promotes the reaction [Apigenin results in decreased expression of MCL1 mRNA]
MCL1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:15262975 PMID:21036698 PMID:28025107 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor affects expression EXP Fluorouracil affects the expression of MCM10 mRNA CTD PMID:16584549 NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 affects response to substance EXP MCM2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,223...127,622,436 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of MCM3 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM3 mRNA]		 CTD PMID:15016801 PMID:16709241 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 affects expression EXP Fluorouracil affects the expression of MCM4 mRNA CTD PMID:15205334 NCBI chr 8:47,960,941...47,978,160
Ensembl chr 8:47,960,185...47,978,160 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM6 mRNA] CTD PMID:15016801 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 affects response to substance
multiple interactions		 EXP MCM7 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM7 mRNA]		 CTD PMID:15016801 PMID:15548681 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940 		JBrowse link
G MCMBP minichromosome maintenance complex binding protein increases expression EXP Fluorouracil results in increased expression of MCMBP mRNA CTD PMID:17039268 NCBI chr10:119,829,440...119,873,581
Ensembl chr10:119,829,404...119,892,556 		JBrowse link
G MDFI MyoD family inhibitor decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MDFI protein
MDFI protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 6:41,637,018...41,654,244
Ensembl chr 6:41,636,882...41,654,244 		JBrowse link
G MDFIC MyoD family inhibitor domain containing affects expression EXP Fluorouracil affects the expression of MDFIC mRNA CTD PMID:16584549 NCBI chr 7:114,922,094...115,019,917
Ensembl chr 7:114,922,094...115,019,917 		JBrowse link
G MDM2 MDM2 proto-oncogene multiple interactions
increases phosphorylation
increases expression		 EXP
ISO		 Cadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of MDM2 protein]; Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 protein]
Fluorouracil results in increased expression of MDM2 mRNA; Fluorouracil results in increased expression of MDM2 protein; Fluorouracil results in increased expression of MDM2 protein modified form		 CTD PMID:14665630 PMID:15546879 PMID:16557594 PMID:16949053 PMID:17982676 More... NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MDM4 MDM4 regulator of p53 multiple interactions EXP MDM4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr 1:204,516,406...204,558,120
Ensembl chr 1:204,516,379...204,558,120 		JBrowse link
G MED13L mediator complex subunit 13L multiple interactions EXP MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:115,958,576...116,277,693
Ensembl chr12:115,957,905...116,277,693 		JBrowse link
G MEF2B myocyte enhancer factor 2B affects expression EXP Fluorouracil affects the expression of MEF2B mRNA CTD PMID:16584549 NCBI chr19:19,145,567...19,170,263
Ensembl chr19:19,145,567...19,192,131 		JBrowse link
G MELK maternal embryonic leucine zipper kinase affects response to substance
multiple interactions		 EXP MELK protein affects the susceptibility to Fluorouracil
MELK mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]		 CTD PMID:15548681 PMID:16896004 NCBI chr 9:36,572,895...36,677,682
Ensembl chr 9:36,572,862...36,677,683 		JBrowse link
G MEOX1 mesenchyme homeobox 1 increases expression EXP Fluorouracil results in increased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922 		JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 decreases expression ISO Fluorouracil results in decreased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249 		JBrowse link
G MESP2 mesoderm posterior bHLH transcription factor 2 increases expression EXP Fluorouracil results in increased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr15:89,776,332...89,778,754
Ensembl chr15:89,760,591...89,778,754 		JBrowse link
G METAP2 methionyl aminopeptidase 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of METAP2 mRNA] CTD PMID:15016801 NCBI chr12:95,474,152...95,515,839
Ensembl chr12:95,473,520...95,515,839 		JBrowse link
G METRN meteorin, glial cell differentiation regulator multiple interactions EXP METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr16:715,118...719,655
Ensembl chr16:715,118...719,655 		JBrowse link
G MFN1 mitofusin 1 increases expression EXP Fluorouracil results in increased expression of MFN1 protein CTD PMID:30518710 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MFN2 mitofusin 2 affects expression
increases expression		 EXP Fluorouracil affects the expression of MFN2 mRNA
Fluorouracil results in increased expression of MFN2 protein		 CTD PMID:16584549 PMID:30518710 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MGAT2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase affects response to substance EXP MGAT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:49,620,799...49,623,481
Ensembl chr14:49,620,799...49,623,481 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase decreases expression
multiple interactions
decreases response to substance		 EXP Fluorouracil results in decreased expression of MGMT mRNA; Fluorouracil results in decreased expression of MGMT protein
O(6)-benzylguanine inhibits the reaction [MGMT protein results in decreased susceptibility to Fluorouracil]		 CTD PMID:17487405 PMID:24737281 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MICA MHC class I polypeptide-related sequence A affects response to substance EXP MICA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315 		JBrowse link
G MICB MHC class I polypeptide-related sequence B affects response to substance EXP MICB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,494,918...31,511,124
Ensembl chr 6:31,494,881...31,511,124 		JBrowse link
G MIR532 microRNA 532 multiple interactions EXP [Melatonin results in increased expression of MIR532] which results in increased susceptibility to Fluorouracil CTD PMID:37755321 NCBI chr  X:50,003,148...50,003,238
Ensembl chr  X:50,003,148...50,003,238 		JBrowse link
G MIR577 microRNA 577 increases response to substance EXP MIR577 mRNA results in increased susceptibility to Fluorouracil CTD PMID:28150434 NCBI chr 4:114,656,759...114,656,854
Ensembl chr 4:114,656,759...114,656,854 		JBrowse link
G MKI67 marker of proliferation Ki-67 affects response to substance
affects expression
decreases expression		 EXP
ISO		 MKI67 mRNA affects the susceptibility to Fluorouracil; MKI67 protein affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of MKI67 protein
Fluorouracil results in decreased expression of MKI67 protein
Fluorouracil results in decreased expression of MKI67; Fluorouracil results in decreased expression of MKI67 mRNA		 CTD PMID:11300326 PMID:15205334 PMID:15548681 PMID:16709241 PMID:18286688 More... NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MKX mohawk homeobox decreases expression EXP Fluorouracil results in decreased expression of MKX mRNA CTD PMID:16510598 NCBI chr10:27,672,874...27,745,819
Ensembl chr10:27,672,874...27,746,060 		JBrowse link
G MLF1 myeloid leukemia factor 1 affects expression ISO Fluorouracil affects the expression of MLF1 mRNA CTD PMID:20421339 NCBI chr 3:158,571,194...158,606,456
Ensembl chr 3:158,571,163...158,607,252 		JBrowse link
G MLH1 mutL homolog 1 affects response to substance
increases response to substance		 EXP MLH1 mRNA affects the susceptibility to Fluorouracil; MLH1 protein affects the susceptibility to Fluorouracil
MLH1 protein results in increased susceptibility to Fluorouracil		 CTD PMID:17914563 PMID:18497967 PMID:18949393 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor affects response to substance EXP MLLT11 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544 		JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MMP1 mRNA]
Fluorouracil results in increased expression of MMP1 mRNA		 CTD PMID:15016801 PMID:19528421 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
decreases activity		 EXP
ISO		 MMP2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]
Fluorouracil results in decreased activity of MMP2 protein
Fluorouracil promotes the reaction [Valsartan results in decreased activity of MMP2 protein]; Valsartan promotes the reaction [Fluorouracil results in decreased activity of MMP2 protein]		 CTD PMID:18678097 PMID:35235860 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions EXP MMP3 promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin] CTD PMID:15102660 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 affects expression
multiple interactions
increases expression		 EXP
ISO		 Fluorouracil affects the expression of MMP9 mRNA
Fluorouracil promotes the reaction [Valsartan results in decreased activity of MMP9 protein]
Fluorouracil results in increased expression of MMP9 protein		 CTD PMID:15205334 PMID:26310874 PMID:35235860 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MMS19 MMS19 homolog, cytosolic iron-sulfur assembly component multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of MMS19 mRNA] CTD PMID:15016801 NCBI chr10:97,458,324...97,498,794
Ensembl chr10:97,458,324...97,498,794 		JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 decreases expression ISO Fluorouracil results in decreased expression of MNX1 protein CTD PMID:21296659 NCBI chr 7:157,004,854...157,010,663
Ensembl chr 7:156,994,051...157,010,663 		JBrowse link
G MORF4L2 mortality factor 4 like 2 decreases response to substance EXP MORF4L2 mRNA results in decreased susceptibility to Fluorouracil CTD PMID:18593893 NCBI chr  X:103,675,498...103,688,047
Ensembl chr  X:103,675,496...103,688,158 		JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 affects response to substance EXP MPC2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:167,916,675...167,937,072
Ensembl chr 1:167,916,675...167,937,072 		JBrowse link
G MPIG6B megakaryocyte and platelet inhibitory receptor G6b affects response to substance EXP MPIG6B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:31,720,296...31,726,714
Ensembl chr 6:31,718,594...31,726,714 		JBrowse link
G MPO myeloperoxidase multiple interactions
increases expression
increases activity		 ISO Ascorbic Acid inhibits the reaction [Fluorouracil results in increased activity of MPO protein]; Silybin inhibits the reaction [Fluorouracil results in increased expression of MPO protein] CTD PMID:26921358 PMID:37335224 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MPP7 MAGUK p55 scaffold protein 7 decreases expression EXP Fluorouracil results in decreased expression of MPP7 mRNA CTD PMID:16510598 NCBI chr10:28,050,993...28,335,203
Ensembl chr10:28,050,993...28,334,486 		JBrowse link
G MPRIP myosin phosphatase Rho interacting protein affects response to substance EXP MPRIP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:17,042,457...17,192,643
Ensembl chr17:17,042,457...17,217,679 		JBrowse link
G MR1 major histocompatibility complex, class I-related increases expression EXP Fluorouracil results in increased expression of MR1 mRNA CTD PMID:16101138 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938 		JBrowse link
G MRAS muscle RAS oncogene homolog affects expression EXP Fluorouracil affects the expression of MRAS mRNA CTD PMID:16584549 NCBI chr 3:138,347,648...138,405,535
Ensembl chr 3:138,347,648...138,405,534 		JBrowse link
G MSH2 mutS homolog 2 affects response to substance
decreases expression		 EXP MSH2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of MSH2 mRNA		 CTD PMID:16557594 PMID:16709241 PMID:18949393 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146 		JBrowse link
G MSX2 msh homeobox 2 affects response to substance
decreases expression		 EXP MSX2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of MSX2 protein		 CTD PMID:15352031 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of ATP6 mRNA CTD PMID:16391804 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT1E metallothionein 1E increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of MT1E protein
MT1E protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1M metallothionein 1M increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of MT1M protein
MT1M protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr16:56,632,659...56,633,981
Ensembl chr16:56,632,659...56,633,981 		JBrowse link
G MT1X metallothionein 1X decreases expression EXP Fluorouracil results in decreased expression of MT1X mRNA CTD PMID:17039268 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of MT2A protein
[Fluorouracil co-treated with EGF protein] results in increased expression of MT2A mRNA; [Fluorouracil co-treated with IGF1 protein] results in increased expression of MT2A mRNA; [Fluorouracil co-treated with IL6 protein] results in increased expression of MT2A mRNA; [Fluorouracil co-treated with TGFB1 protein] results in increased expression of MT2A mRNA; EGF protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; IGF1 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; IL6 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]]; TGFB1 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]		 CTD PMID:28507149 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTAP methylthioadenosine phosphorylase decreases expression EXP Fluorouracil results in decreased expression of MTAP mRNA CTD PMID:16510598 NCBI chr 9:21,802,636...21,941,115
Ensembl chr 9:21,802,636...21,937,651 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase multiple interactions
increases response to substance
increases metabolic processing
affects response to substance		 EXP MTHFR gene polymorphism results in increased susceptibility to [Fluorouracil co-treated with Leucovorin]
MTHFR gene polymorphism results in increased susceptibility to Fluorouracil
MTHFR protein results in increased metabolism of Fluorouracil
MTHFR gene polymorphism affects the susceptibility to Fluorouracil; MTHFR protein affects the susceptibility to Fluorouracil; MTHFR protein affects the susceptibility to Fluorouracil analog		 CTD PMID:15608557 PMID:15735113 PMID:16399440 PMID:16785472 PMID:17047490 More... NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions
decreases expression		 EXP rebamipide inhibits the reaction [Fluorouracil results in decreased expression of MTOR protein modified form]
Fluorouracil results in decreased expression of MTOR mRNA; Fluorouracil results in decreased expression of MTOR protein modified form		 CTD PMID:29054700 PMID:34748853 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTTP microsomal triglyceride transfer protein decreases expression EXP Fluorouracil results in decreased expression of MTTP mRNA CTD PMID:32535746 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 increases expression ISO Fluorouracil results in increased expression of MTUS1 mRNA CTD PMID:19272435 NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094 		JBrowse link
G MVP major vault protein multiple interactions
increases expression		 EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of MVP mRNA; Fluorouracil promotes the reaction [YBX1 protein binds to MVP promoter]
Fluorouracil results in increased expression of MVP mRNA; Fluorouracil results in increased expression of MVP protein		 CTD PMID:15750632 PMID:32800223 NCBI chr16:29,820,394...29,848,039
Ensembl chr16:29,820,394...29,848,039 		JBrowse link
G MXI1 MAX interactor 1, dimerization protein affects response to substance EXP MXI1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:110,207,605...110,287,365
Ensembl chr10:110,207,605...110,287,365 		JBrowse link
G MYB MYB proto-oncogene, transcription factor decreases expression
affects response to substance		 EXP
ISO		 Fluorouracil results in decreased expression of MYB mRNA
MYB protein affects the susceptibility to Fluorouracil		 CTD PMID:15235111 PMID:15548681 PMID:16557594 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
G MYBL2 MYB proto-oncogene like 2 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of MYBL2 mRNA
MYBL2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15548681 PMID:16557594 NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
affects expression
increases expression
multiple interactions
decreases response to substance
affects response to substance		 EXP
ISO		 Fluorouracil results in decreased expression of MYC mRNA; Fluorouracil results in decreased expression of MYC protein
Fluorouracil affects the expression of MYC mRNA
Fluorouracil results in increased expression of MYC protein
[Cadmium Chloride co-treated with Fluorouracil] affects the expression of MYC protein; [Fluorouracil co-treated with Cadmium Chloride] affects the expression of MYC mRNA; TP53 protein promotes the reaction [Fluorouracil results in decreased expression of MYC mRNA]
MYC protein results in decreased susceptibility to Fluorouracil
MYC protein affects the susceptibility to Fluorouracil		 CTD PMID:15585135 PMID:16557594 PMID:16709241 PMID:16803524 PMID:17628013 More... NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYCL MYCL proto-oncogene, bHLH transcription factor decreases expression ISO Fluorouracil results in decreased expression of MYCL mRNA CTD PMID:19272435 NCBI chr 1:39,895,428...39,901,917
Ensembl chr 1:39,895,428...39,902,256 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Fluorouracil results in decreased expression of MYCN mRNA CTD PMID:19272435 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of MYD88 protein
Bosentan inhibits the reaction [Fluorouracil results in increased expression of MYD88 protein]		 CTD PMID:34800596 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYF5 myogenic factor 5 affects expression ISO Fluorouracil affects the expression of MYF5 protein CTD PMID:21296659 NCBI chr12:80,716,912...80,719,671
Ensembl chr12:80,716,912...80,719,671 		JBrowse link
G MYL4 myosin light chain 4 decreases expression EXP Fluorouracil results in decreased expression of MYL4 mRNA CTD PMID:24737281 NCBI chr17:47,189,433...47,227,650
Ensembl chr17:47,200,446...47,223,679 		JBrowse link
G MYL9 myosin light chain 9 affects response to substance EXP MYL9 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G MYLIP myosin regulatory light chain interacting protein affects expression EXP Fluorouracil affects the expression of MYLIP mRNA CTD PMID:16584549 NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,151,367 		JBrowse link
G MYO1E myosin IE increases expression EXP Fluorouracil results in increased expression of MYO1E protein CTD PMID:15331170 NCBI chr15:59,132,434...59,372,871
Ensembl chr15:59,132,434...59,372,871 		JBrowse link
G MYO6 myosin VI affects response to substance EXP MYO6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:75,749,239...75,919,537
Ensembl chr 6:75,749,201...75,919,537 		JBrowse link
G MYOD1 myogenic differentiation 1 decreases expression ISO Fluorouracil results in decreased expression of MYOD1 protein CTD PMID:21296659 NCBI chr11:17,719,571...17,722,136
Ensembl chr11:17,719,571...17,722,136 		JBrowse link
G MYOF myoferlin decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of MYOF protein
MYOF protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein decreases expression EXP Fluorouracil results in decreased expression of NAF1 mRNA CTD PMID:16510598 NCBI chr 4:163,103,929...163,166,890
Ensembl chr 4:163,110,073...163,166,890 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein decreases expression EXP Fluorouracil results in decreased expression of NAIP mRNA CTD PMID:16101138 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NANOG Nanog homeobox affects expression
decreases expression		 ISO
EXP		 Fluorouracil affects the expression of NANOG protein
Fluorouracil results in decreased expression of NANOG mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146 		JBrowse link
G NASP nuclear autoantigenic sperm protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NASP mRNA] CTD PMID:15016801 NCBI chr 1:45,584,041...45,618,893
Ensembl chr 1:45,583,846...45,618,904 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist decreases expression EXP Fluorouracil results in decreased expression of NBL1 mRNA CTD PMID:16709241 NCBI chr 1:19,643,229...19,658,452
Ensembl chr 1:19,596,979...19,658,456 		JBrowse link
G NBN nibrin multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NBN mRNA] CTD PMID:15016801 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228 		JBrowse link
G NBPF10 NBPF member 10 increases expression EXP Fluorouracil results in increased expression of NBPF10 mRNA CTD PMID:16510598 NCBI chr 1:146,064,699...146,144,804
Ensembl chr 1:146,064,711...146,229,000 		JBrowse link
G NCAPG non-SMC condensin I complex subunit G multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NCAPG mRNA] CTD PMID:15016801 NCBI chr 4:17,810,979...17,844,865
Ensembl chr 4:17,810,979...17,844,865 		JBrowse link
G NCL nucleolin affects splicing EXP Fluorouracil affects the splicing of NCL mRNA CTD PMID:17169984 NCBI chr 2:231,453,531...231,464,484
Ensembl chr 2:231,453,531...231,483,641 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 multiple interactions EXP NCOR1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185 		JBrowse link
G NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 affects response to substance
increases expression		 EXP NDUFA10 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of NDUFA10 protein		 CTD PMID:15548681 PMID:15585135 PMID:16803524 NCBI chr 2:239,892,442...240,025,342
Ensembl chr 2:239,892,450...240,025,743 		JBrowse link
G NDUFA4 NDUFA4 mitochondrial complex associated affects expression EXP Fluorouracil affects the expression of NDUFA4 mRNA CTD PMID:34151400 NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153 		JBrowse link
G NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 affects expression EXP Fluorouracil affects the expression of NDUFA6 mRNA CTD PMID:34151400 NCBI chr22:42,085,526...42,090,772
Ensembl chr22:42,085,526...42,090,884 		JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 affects expression EXP Fluorouracil affects the expression of NDUFAB1 mRNA CTD PMID:34151400 NCBI chr16:23,581,014...23,596,316
Ensembl chr16:23,581,014...23,596,316 		JBrowse link
G NDUFAF1 NADH:ubiquinone oxidoreductase complex assembly factor 1 increases expression EXP Fluorouracil results in increased expression of NDUFAF1 mRNA CTD PMID:34151400 NCBI chr15:41,387,353...41,403,026
Ensembl chr15:41,387,218...41,409,403 		JBrowse link
G NDUFAF3 NADH:ubiquinone oxidoreductase complex assembly factor 3 decreases expression EXP Fluorouracil results in decreased expression of NDUFAF3 mRNA CTD PMID:34151400 NCBI chr 3:49,020,452...49,023,495
Ensembl chr 3:49,020,459...49,023,495 		JBrowse link
G NDUFAF4 NADH:ubiquinone oxidoreductase complex assembly factor 4 affects expression EXP Fluorouracil affects the expression of NDUFAF4 mRNA CTD PMID:34151400 NCBI chr 6:96,889,315...96,897,891
Ensembl chr 6:96,889,315...96,897,891 		JBrowse link
G NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 affects expression EXP Fluorouracil affects the expression of NDUFB10 mRNA CTD PMID:34151400 NCBI chr16:1,959,538...1,961,975
Ensembl chr16:1,959,538...1,961,975 		JBrowse link
G NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 increases expression EXP Fluorouracil results in increased expression of NDUFB2 mRNA CTD PMID:34151400 NCBI chr 7:140,696,708...140,706,643
Ensembl chr 7:140,690,777...140,722,790 		JBrowse link
G NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 affects expression EXP Fluorouracil affects the expression of NDUFB9 mRNA CTD PMID:34151400 NCBI chr 8:124,539,123...124,549,979
Ensembl chr 8:124,539,101...124,580,648 		JBrowse link
G NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 affects expression EXP Fluorouracil affects the expression of NDUFC1 mRNA CTD PMID:34151400 NCBI chr 4:139,289,917...139,302,551
Ensembl chr 4:139,266,880...139,302,551 		JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 affects expression EXP Fluorouracil affects the expression of NDUFV1 mRNA CTD PMID:34151400 NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554 		JBrowse link
G NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP Fluorouracil results in increased expression of NDUFV3 mRNA CTD PMID:34151400 NCBI chr21:42,893,309...42,913,299
Ensembl chr21:42,879,644...42,913,304 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase affects response to substance EXP NEDD4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G NEK1 NIMA related kinase 1 decreases expression EXP Fluorouracil results in decreased expression of NEK1 mRNA CTD PMID:16709241 NCBI chr 4:169,392,809...169,612,583
Ensembl chr 4:169,369,704...169,612,632 		JBrowse link
G NEK2 NIMA related kinase 2 multiple interactions
decreases expression		 EXP
ISO		 TP53 protein affects the reaction [Fluorouracil results in decreased expression of NEK2 mRNA] CTD PMID:15016801 PMID:19272435 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630 		JBrowse link
G NEK4 NIMA related kinase 4 decreases expression EXP Fluorouracil results in decreased expression of NEK4 mRNA CTD PMID:16709241 NCBI chr 3:52,708,444...52,770,940
Ensembl chr 3:52,708,444...52,770,946 		JBrowse link
G NEK6 NIMA related kinase 6 decreases expression EXP Fluorouracil results in decreased expression of NEK6 mRNA CTD PMID:17039268 NCBI chr 9:124,257,606...124,353,307
Ensembl chr 9:124,257,606...124,353,307 		JBrowse link
G NEK9 NIMA related kinase 9 decreases expression EXP Fluorouracil results in decreased expression of NEK9 mRNA CTD PMID:16709241 NCBI chr14:75,079,353...75,127,202
Ensembl chr14:75,079,353...75,127,344 		JBrowse link
G NES nestin decreases expression ISO Fluorouracil results in decreased expression of NES mRNA; Fluorouracil results in decreased expression of NES protein CTD PMID:21296659 PMID:26272751 NCBI chr 1:156,668,763...156,677,407
Ensembl chr 1:156,668,763...156,677,407 		JBrowse link
G NETO2 neuropilin and tolloid like 2 affects response to substance EXP NETO2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:47,077,703...47,143,945
Ensembl chr16:47,077,703...47,143,945 		JBrowse link
G NEUROD1 neuronal differentiation 1 affects expression
decreases expression		 EXP
ISO		 Fluorouracil affects the expression of NEUROD1 mRNA
Fluorouracil results in decreased expression of NEUROD1 protein		 CTD PMID:16584549 PMID:21296659 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NEUROG2 neurogenin 2 decreases expression EXP Fluorouracil results in decreased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 4:112,513,516...112,516,180
Ensembl chr 4:112,513,516...112,516,180 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects response to substance
multiple interactions
affects localization
decreases expression
affects expression
decreases response to substance		 EXP
ISO		 NFE2L2 protein affects the susceptibility to Fluorouracil
Ascorbic Acid promotes the reaction [Fluorouracil affects the localization of NFE2L2 protein]
Fluorouracil results in decreased expression of NFE2L2 protein
Fluorouracil affects the expression of NFE2L2 mRNA
NFE2L2 results in decreased susceptibility to Fluorouracil
NFE2L2 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:18692501 PMID:20722640 PMID:21489257 PMID:26921358 PMID:34151400 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFE2L3 NFE2 like bZIP transcription factor 3 increases expression EXP Fluorouracil results in increased expression of NFE2L3 mRNA CTD PMID:24737281 NCBI chr 7:26,152,198...26,187,137
Ensembl chr 7:26,152,198...26,187,137 		JBrowse link
G NFIB nuclear factor I B decreases expression EXP Fluorouracil results in decreased expression of NFIB mRNA CTD PMID:16557594 NCBI chr 9:14,081,843...14,532,077
Ensembl chr 9:14,081,843...14,398,983 		JBrowse link
G NFIC nuclear factor I C increases expression EXP Fluorouracil results in increased expression of NFIC mRNA CTD PMID:16584549 NCBI chr19:3,359,630...3,469,217
Ensembl chr19:3,314,403...3,469,217 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
affects localization
increases phosphorylation
decreases response to substance		 EXP
ISO		 [N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] affects the localization of NFKB1 protein; [N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] results in decreased expression of [NFKB1 protein binds to RELA protein]; resveratrol inhibits the reaction [Fluorouracil results in increased phosphorylation of NFKB1 protein]
Ascorbic Acid inhibits the reaction [Fluorouracil affects the localization of NFKB1 protein]
NFKB1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:15548681 PMID:16637064 PMID:26310874 PMID:26921358 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha affects activity
increases phosphorylation
decreases expression
multiple interactions
increases expression
decreases degradation		 EXP
ISO		 Fluorouracil affects the activity of NFKBIA protein
Fluorouracil results in increased phosphorylation of NFKBIA protein
Fluorouracil results in decreased expression of NFKBIA protein
Curcumin inhibits the reaction [Fluorouracil results in decreased expression of NFKBIA protein]
[N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] results in decreased expression of NFKBIA protein; Fluorouracil results in increased phosphorylation of and results in increased activity of NFKBIA protein; resveratrol inhibits the reaction [Fluorouracil results in increased phosphorylation of NFKBIA protein]
Fluorouracil results in increased expression of NFKBIA protein
Fluorouracil results in decreased degradation of NFKBIA protein		 CTD PMID:10891390 PMID:12941601 PMID:16337965 PMID:16637064 PMID:16929163 More... NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFYA nuclear transcription factor Y subunit alpha multiple interactions EXP Fluorouracil inhibits the reaction [NFYA protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]] CTD PMID:27129209 NCBI chr 6:41,072,974...41,102,403
Ensembl chr 6:41,072,974...41,102,403 		JBrowse link
G NFYB nuclear transcription factor Y subunit beta affects expression
multiple interactions		 ISO
EXP		 Fluorouracil affects the expression of NFYB mRNA
Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]]		 CTD PMID:20421339 PMID:27129209 NCBI chr12:104,117,086...104,138,210
Ensembl chr12:104,117,086...104,138,241 		JBrowse link
G NGFR nerve growth factor receptor increases response to substance ISO TNFRSF10B protein results in increased susceptibility to Fluorouracil CTD PMID:15374982 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NINJ1 ninjurin 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of NINJ1 mRNA] CTD PMID:15016801 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251 		JBrowse link
G NIPSNAP2 nipsnap homolog 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NIPSNAP2 mRNA] CTD PMID:15016801 NCBI chr 7:55,964,585...56,000,179
Ensembl chr 7:55,951,793...56,000,181 		JBrowse link
G NKAIN1 sodium/potassium transporting ATPase interacting 1 multiple interactions EXP NKAIN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:31,179,745...31,239,887
Ensembl chr 1:31,179,745...31,239,887 		JBrowse link
G NKIRAS1 NFKB inhibitor interacting Ras like 1 affects expression EXP Fluorouracil affects the expression of NKIRAS1 mRNA CTD PMID:16584549 NCBI chr 3:23,889,951...23,946,562
Ensembl chr 3:23,889,951...23,946,591 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 affects response to substance EXP NME1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NME4 NME/NM23 nucleoside diphosphate kinase 4 affects response to substance EXP NME4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:396,729...400,754
Ensembl chr16:396,725...410,367 		JBrowse link
G NODAL nodal growth differentiation factor decreases expression ISO Fluorouracil results in decreased expression of NODAL protein CTD PMID:21296659 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951 		JBrowse link
G NOG noggin decreases expression ISO Fluorouracil results in decreased expression of NOG protein CTD PMID:21296659 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOM1 nucleolar protein with MIF4G domain 1 decreases expression EXP Fluorouracil results in decreased expression of NOM1 mRNA CTD PMID:16510598 NCBI chr 7:156,949,712...156,973,176
Ensembl chr 7:156,949,712...156,973,176 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of NOS2 protein
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of NOS2 mRNA]
Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Fluorouracil results in increased expression of and results in increased activity of NOS2 protein		 CTD PMID:12150722 PMID:16724238 PMID:18069768 PMID:31129132 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases expression		 ISO Bosentan inhibits the reaction [Fluorouracil results in decreased expression of NOS3 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of NOS3 mRNA] CTD PMID:31129132 PMID:34800596 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH1 notch receptor 1 multiple interactions EXP [Fluorouracil co-treated with Chloroquine] results in increased expression of NOTCH1 protein CTD PMID:29917191 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NPM1 nucleophosmin 1 decreases response to substance EXP NPM1 protein results in decreased susceptibility to Fluorouracil CTD PMID:24736981 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810 		JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 decreases expression EXP Fluorouracil results in decreased expression of NPM3 mRNA CTD PMID:16510598 NCBI chr10:101,781,325...101,783,446
Ensembl chr10:101,781,325...101,783,446 		JBrowse link
G NPPA natriuretic peptide A increases expression ISO Fluorouracil results in increased expression of NPPA protein CTD PMID:21296659 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Fluorouracil results in decreased expression of NQO1 protein CTD PMID:35101590 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1D2 nuclear receptor subfamily 1 group D member 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NR1D2 mRNA] CTD PMID:15016801 NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,637 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 affects expression EXP Fluorouracil affects the expression of NR4A1 mRNA CTD PMID:15205334 PMID:16557594 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 affects expression ISO Fluorouracil affects the expression of NR5A2 protein CTD PMID:21296659 NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420 		JBrowse link
G NR6A1 nuclear receptor subfamily 6 group A member 1 decreases expression ISO Fluorouracil results in decreased expression of NR6A1 protein CTD PMID:21296659 NCBI chr 9:124,517,275...124,771,311
Ensembl chr 9:124,517,275...124,771,311 		JBrowse link
G NRG1 neuregulin 1 affects response to substance EXP NRG1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G NRIP1 nuclear receptor interacting protein 1 multiple interactions
decreases expression		 EXP [Fluorouracil co-treated with irinotecan] results in increased expression of NRIP1 mRNA
Fluorouracil results in decreased expression of NRIP1 mRNA		 CTD PMID:16391804 PMID:16510598 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936 		JBrowse link
G NRP1 neuropilin 1 decreases response to substance EXP NRP1 protein results in decreased susceptibility to Fluorouracil CTD PMID:15956974 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G NT5C1A 5'-nucleotidase, cytosolic IA decreases response to substance
multiple interactions		 ISO NT5C1A protein results in decreased susceptibility to Fluorouracil
NT5C1A protein results in decreased susceptibility to [Fluorouracil co-treated with Cladribine]		 CTD PMID:16362297 NCBI chr 1:39,651,229...39,672,107
Ensembl chr 1:39,651,229...39,672,107 		JBrowse link
G NT5E 5'-nucleotidase ecto increases expression EXP Fluorouracil results in increased expression of NT5E mRNA CTD PMID:24737281 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791 		JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial increases expression EXP Fluorouracil results in increased expression of NT5M mRNA CTD PMID:19219653 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663 		JBrowse link
G NTN4 netrin 4 increases expression EXP Fluorouracil results in increased expression of NTN4 mRNA CTD PMID:17039268 NCBI chr12:95,657,807...95,791,155
Ensembl chr12:95,657,807...95,791,189 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of NTRK2 protein
NTRK2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G NTS neurotensin affects response to substance EXP NTS protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992 		JBrowse link
G NTSR1 neurotensin receptor 1 affects response to substance
decreases expression		 EXP NTSR1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of NTSR1 protein		 CTD PMID:15352031 NCBI chr20:62,708,836...62,762,771
Ensembl chr20:62,708,836...62,762,771 		JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 multiple interactions
decreases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of NUCKS1 mRNA]
Fluorouracil results in decreased expression of NUCKS1 protein		 CTD PMID:15016801 PMID:15585135 PMID:16803524 NCBI chr 1:205,712,822...205,750,182
Ensembl chr 1:205,712,822...205,750,182 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator affects expression EXP Fluorouracil affects the expression of NUPR1 mRNA CTD PMID:16584549 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 increases expression EXP Fluorouracil results in increased expression of OAS2 mRNA CTD PMID:16557594 NCBI chr12:112,978,519...113,011,723
Ensembl chr12:112,978,395...113,011,723 		JBrowse link
G ODC1 ornithine decarboxylase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ODC1 mRNA] CTD PMID:15016801 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G OGFRL1 opioid growth factor receptor like 1 affects response to substance EXP OGFRL1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:71,288,811...71,309,059
Ensembl chr 6:71,288,811...71,309,059 		JBrowse link
G OLFM1 olfactomedin 1 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of OLFM1 protein
OLFM1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 9:135,075,505...135,121,184
Ensembl chr 9:135,075,422...135,121,180 		JBrowse link
G OLFM4 olfactomedin 4 decreases expression ISO Fluorouracil results in decreased expression of OLFM4 protein CTD PMID:36203040 NCBI chr13:53,028,813...53,052,057
Ensembl chr13:53,028,813...53,052,057 		JBrowse link
G OLIG2 oligodendrocyte transcription factor 2 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of OLIG2 mRNA; Fluorouracil results in decreased expression of OLIG2 protein
[HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]		 CTD PMID:21296659 PMID:25178657 NCBI chr21:33,025,935...33,029,185
Ensembl chr21:33,025,935...33,029,196 		JBrowse link
G OLIG3 oligodendrocyte transcription factor 3 decreases expression EXP Fluorouracil results in decreased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 6:137,492,199...137,494,394
Ensembl chr 6:137,492,199...137,494,394 		JBrowse link
G OPTN optineurin affects response to substance
increases expression		 EXP OPTN protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of OPTN mRNA		 CTD PMID:16101138 PMID:16217747 PMID:17039268 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G ORC3 origin recognition complex subunit 3 decreases expression ISO Fluorouracil results in decreased expression of ORC3 mRNA CTD PMID:19272435 NCBI chr 6:87,590,135...87,677,823
Ensembl chr 6:87,590,067...87,677,823 		JBrowse link
G ORC6 origin recognition complex subunit 6 increases expression EXP Fluorouracil results in increased expression of ORC6 mRNA CTD PMID:16584549 NCBI chr16:46,689,659...46,698,394
Ensembl chr16:46,689,643...46,698,394 		JBrowse link
G OTX2 orthodenticle homeobox 2 decreases expression EXP Fluorouracil results in decreased expression of OTX2 mRNA CTD PMID:30518710 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 multiple interactions
affects response to substance		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of OXCT1 mRNA]
OXCT1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:16217747 NCBI chr 5:41,730,065...41,870,425
Ensembl chr 5:41,730,065...41,870,425 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta decreases expression EXP Fluorouracil results in decreased expression of P4HB mRNA CTD PMID:32535746 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PAFAH1B1 mRNA] CTD PMID:15016801 NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,183...2,685,615 		JBrowse link
G PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases expression EXP Fluorouracil results in increased expression of PAICS mRNA CTD PMID:19219653 NCBI chr 4:56,410,507...56,464,578
Ensembl chr 4:56,435,741...56,464,578 		JBrowse link
G PAIP1 poly(A) binding protein interacting protein 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PAIP1 mRNA] CTD PMID:15016801 NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758 		JBrowse link
G PANK1 pantothenate kinase 1 increases expression EXP Fluorouracil results in increased expression of PANK1 mRNA CTD PMID:16557594 NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,579,497...89,645,242 		JBrowse link
G PAQR8 progestin and adipoQ receptor family member 8 decreases expression EXP Fluorouracil results in decreased expression of PAQR8 mRNA CTD PMID:17039268 NCBI chr 6:52,362,151...52,407,777
Ensembl chr 6:52,361,421...52,407,777 		JBrowse link
G PARD3 par-3 family cell polarity regulator affects response to substance EXP PARD3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases expression
affects expression
increases cleavage
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of PARP1; Fluorouracil results in increased expression of PARP1 mRNA
Fluorouracil affects the expression of PARP1 mRNA
Fluorouracil results in increased cleavage of PARP1 protein
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]; [Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of PARP1 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein]; Celecoxib inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of PARP1 mRNA]; Fluorouracil promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]; Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein; IGF1 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; IL6 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]]; Nicotine inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; S100A11 mutant form promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of PARP1 mRNA]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]; Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein		 CTD PMID:11300326 PMID:15896711 PMID:15996812 PMID:16525653 PMID:17461495 More... NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PARP14 poly(ADP-ribose) polymerase family member 14 increases expression EXP Fluorouracil results in increased expression of PARP14 mRNA CTD PMID:17039268 NCBI chr 3:122,680,839...122,730,840
Ensembl chr 3:122,680,839...122,730,840 		JBrowse link
G PAX3 paired box 3 decreases expression EXP Fluorouracil results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 2:222,199,887...222,298,998
Ensembl chr 2:222,199,887...222,298,998 		JBrowse link
G PAX6 paired box 6 increases expression
decreases expression		 ISO
EXP		 Fluorouracil results in increased expression of PAX6 protein
Fluorouracil results in decreased expression of PAX6 mRNA		 CTD PMID:21296659 PMID:30518710 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PBX3 PBX homeobox 3 affects response to substance EXP PBX3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:125,747,373...125,967,377
Ensembl chr 9:125,747,345...125,967,377 		JBrowse link
G PCDHA5 protocadherin alpha 5 decreases expression EXP Fluorouracil results in decreased expression of PCDHA5 protein CTD PMID:15585135 PMID:16803524 NCBI chr 5:140,821,613...141,012,347
Ensembl chr 5:140,821,604...141,012,347 		JBrowse link
G PCLAF PCNA clamp associated factor multiple interactions
decreases expression		 EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of PCLAF mRNA
Fluorouracil results in decreased expression of PCLAF mRNA		 CTD PMID:16391804 PMID:17039268 NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression
multiple interactions
increases expression		 EXP
ISO		 Fluorouracil results in decreased expression of PCNA protein
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of PCNA protein]; Fluorouracil inhibits the reaction [Trichloroacetic Acid results in increased expression of PCNA protein]
Probucol inhibits the reaction [Fluorouracil results in decreased expression of PCNA protein]
Fluorouracil results in increased expression of PCNA mRNA		 CTD PMID:16557594 PMID:16709241 PMID:18205257 PMID:19272435 PMID:29678497 More... NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 affects response to substance EXP PCOLCE2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:142,817,874...142,889,083
Ensembl chr 3:142,815,922...142,889,206 		JBrowse link
G PDAP1 PDGFA associated protein 1 decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of PDAP1 mRNA
Fluorouracil results in increased expression of PDAP1 protein		 CTD PMID:15585135 PMID:16709241 PMID:16803524 NCBI chr 7:99,394,673...99,408,597
Ensembl chr 7:99,392,048...99,408,597 		JBrowse link
G PDCD1LG2 programmed cell death 1 ligand 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PDCD1LG2 mRNA] CTD PMID:15016801 NCBI chr 9:5,510,531...5,571,282
Ensembl chr 9:5,510,531...5,571,282 		JBrowse link
G PDCD4 programmed cell death 4 decreases expression EXP Fluorouracil results in decreased expression of PDCD4 mRNA CTD PMID:15109396 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein decreases expression EXP Fluorouracil results in decreased expression of PDCD6IP mRNA CTD PMID:17039268 NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707 		JBrowse link
G PDF peptide deformylase, mitochondrial increases expression
decreases response to substance		 EXP Fluorouracil results in increased expression of PDF mRNA; Fluorouracil results in increased expression of PDF protein
PDF protein results in decreased susceptibility to Fluorouracil		 CTD PMID:16510598 NCBI chr16:69,326,913...69,330,588
Ensembl chr16:69,326,913...69,330,588 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 decreases expression EXP Fluorouracil results in decreased expression of PDIA4 mRNA CTD PMID:16709241 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDLIM5 PDZ and LIM domain 5 affects response to substance EXP PDLIM5 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 decreases expression ISO Fluorouracil results in decreased expression of IPF1 protein CTD PMID:21296659 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G PDXK pyridoxal kinase decreases expression EXP Fluorouracil results in decreased expression of PDXK mRNA CTD PMID:16510598 NCBI chr21:43,719,129...43,762,299
Ensembl chr21:43,719,094...43,762,307 		JBrowse link
G PDXP pyridoxal phosphatase decreases expression EXP Fluorouracil results in decreased expression of PDXP mRNA CTD PMID:16709241 NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of PECAM1 mRNA; Fluorouracil results in decreased expression of PECAM1 protein
Probucol inhibits the reaction [Fluorouracil results in decreased expression of PECAM1 mRNA]; Probucol inhibits the reaction [Fluorouracil results in decreased expression of PECAM1 protein]		 CTD PMID:19272435 PMID:21296659 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PEG10 paternally expressed 10 affects response to substance EXP PEG10 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695 		JBrowse link
G PER1 period circadian regulator 1 decreases expression ISO Fluorouracil results in decreased expression of PER1 mRNA CTD PMID:18329632 NCBI chr17:8,140,472...8,152,404
Ensembl chr17:8,140,467...8,156,506 		JBrowse link
G PER2 period circadian regulator 2 decreases expression ISO Fluorouracil results in decreased expression of PER2 mRNA CTD PMID:18329632 NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102 		JBrowse link
G PFN2 profilin 2 increases expression
multiple interactions
affects response to substance		 EXP Fluorouracil results in increased expression of PFN2 protein
TP53 protein affects the reaction [Fluorouracil results in decreased expression of PFN2 mRNA]
PFN2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:15352031 NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PGLYRP1 mRNA] CTD PMID:15016801 NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053 		JBrowse link
G PGR progesterone receptor affects expression EXP Fluorouracil affects the expression of PGR mRNA CTD PMID:34151400 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PHIP pleckstrin homology domain interacting protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PHIP mRNA] CTD PMID:15016801 NCBI chr 6:78,934,419...79,078,254
Ensembl chr 6:78,934,419...79,078,287 		JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 increases expression EXP Fluorouracil results in increased expression of PHLDA3 mRNA CTD PMID:16557594 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237 		JBrowse link
G PHYH phytanoyl-CoA 2-hydroxylase affects response to substance EXP PHYH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:13,277,799...13,300,064
Ensembl chr10:13,277,796...13,302,412 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PI4KB mRNA] CTD PMID:15016801 NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases expression EXP Fluorouracil results in decreased expression of PIK3CA mRNA mutant form CTD PMID:38423379 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIR pirin affects response to substance
decreases expression		 EXP PIR protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of PIR protein		 CTD PMID:15352031 NCBI chr  X:15,384,799...15,493,333
Ensembl chr  X:15,384,799...15,493,564 		JBrowse link
G PISD phosphatidylserine decarboxylase affects response to substance EXP PISD protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr22:31,618,491...31,662,564
Ensembl chr22:31,618,491...31,662,221 		JBrowse link
G PLA2G4A phospholipase A2 group IVA affects response to substance EXP PLA2G4A protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLAT plasminogen activator, tissue type increases expression EXP Fluorouracil results in increased expression of PLAT mRNA CTD PMID:16101138 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAU plasminogen activator, urokinase affects expression
increases expression		 EXP Fluorouracil affects the expression of PLAU mRNA
Fluorouracil results in increased expression of PLAU mRNA		 CTD PMID:16584549 PMID:24737281 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLCG1 phospholipase C gamma 1 decreases response to substance EXP PLCG1 protein results in decreased susceptibility to Fluorouracil CTD PMID:17531112 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLEKHB1 pleckstrin homology domain containing B1 increases expression EXP Fluorouracil results in increased expression of PLEKHB1 mRNA CTD PMID:16510598 NCBI chr11:73,646,581...73,662,819
Ensembl chr11:73,646,178...73,662,819 		JBrowse link
G PLEKHO1 pleckstrin homology domain containing O1 affects response to substance EXP PLEKHO1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:150,149,646...150,160,065
Ensembl chr 1:150,149,183...150,164,720 		JBrowse link
G PLIN2 perilipin 2 affects response to substance EXP PLIN2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290 		JBrowse link
G PLIN3 perilipin 3 affects response to substance EXP PLIN3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:4,838,341...4,867,667
Ensembl chr19:4,838,341...4,867,694 		JBrowse link
G PLK1 polo like kinase 1 increases expression
decreases expression
multiple interactions		 EXP Fluorouracil results in increased expression of PLK1 protein
Fluorouracil results in decreased expression of PLK mRNA; Fluorouracil results in decreased expression of PLK1 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of PLK1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of PLK1 protein]		 CTD PMID:15016801 PMID:15205334 PMID:16709241 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLK2 polo like kinase 2 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of PLK2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of PLK2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of PLK2 mRNA]		 CTD PMID:15016801 PMID:17982676 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139 		JBrowse link
G PLK3 polo like kinase 3 increases expression EXP Fluorouracil results in increased expression of PLK3 protein CTD PMID:14665630 NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,995 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 increases expression
decreases expression
affects response to substance		 EXP Fluorouracil results in increased expression of PLOD2 protein
Fluorouracil results in decreased expression of PLOD2 mRNA
PLOD2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16557594 NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725 		JBrowse link
G PLP2 proteolipid protein 2 affects response to substance EXP PLP2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:49,171,898...49,175,235
Ensembl chr  X:49,171,898...49,175,235 		JBrowse link
G PLRG1 pleiotropic regulator 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of PLRG1 mRNA CTD PMID:16391804 NCBI chr 4:154,535,005...154,550,400
Ensembl chr 4:154,535,005...154,550,400 		JBrowse link
G PLSCR1 phospholipid scramblase 1 affects response to substance EXP PLSCR1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 affects response to substance
multiple interactions		 EXP PMAIP1 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in increased expression of PMAIP1 mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G PMF1 polyamine modulated factor 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PMF1 mRNA] CTD PMID:15016801 NCBI chr 1:156,213,007...156,240,042
Ensembl chr 1:156,212,993...156,240,042 		JBrowse link
G PMS2P4 PMS1 homolog 2, mismatch repair system component pseudogene 4 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PMS2P4 mRNA] CTD PMID:15016801 NCBI chr 7:67,276,131...67,302,442
Ensembl chr 7:67,295,608...67,299,424 		JBrowse link
G PNMA2 PNMA family member 2 affects response to substance EXP PNMA2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:26,504,701...26,513,872
Ensembl chr 8:26,504,701...26,514,092 		JBrowse link
G PNP purine nucleoside phosphorylase affects response to substance EXP PNP protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094 		JBrowse link
G PNPLA6 patatin like phospholipase domain containing 6 decreases expression ISO Fluorouracil results in decreased expression of PNPLA6 mRNA CTD PMID:26272751 NCBI chr19:7,534,164...7,561,767
Ensembl chr19:7,534,004...7,561,764 		JBrowse link
G PNRC1 proline rich nuclear receptor coactivator 1 increases expression EXP Fluorouracil results in increased expression of PNRC1 mRNA CTD PMID:16510598 NCBI chr 6:89,080,751...89,085,160
Ensembl chr 6:89,080,751...89,085,160 		JBrowse link
G PODXL podocalyxin like decreases expression ISO Fluorouracil results in decreased expression of PODXL protein CTD PMID:21296659 NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217 		JBrowse link
G POLA1 DNA polymerase alpha 1, catalytic subunit decreases expression EXP Fluorouracil results in decreased expression of POLA1 mRNA CTD PMID:19219653 NCBI chr  X:24,693,918...24,996,986
Ensembl chr  X:24,693,873...24,996,986 		JBrowse link
G POLA2 DNA polymerase alpha 2, accessory subunit affects response to substance EXP POLA2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr11:65,261,962...65,305,985
Ensembl chr11:65,261,913...65,305,959 		JBrowse link
G POLE2 DNA polymerase epsilon 2, accessory subunit affects response to substance EXP POLE2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:49,643,555...49,688,214
Ensembl chr14:49,643,555...49,688,422 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit affects response to substance EXP POLG protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861 		JBrowse link
G POSTN periostin decreases response to substance EXP POSTN protein results in decreased susceptibility to Fluorouracil CTD PMID:15731169 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G POU5F1 POU class 5 homeobox 1 decreases expression ISO
EXP		 Fluorouracil results in decreased expression of POU5F1 protein
Fluorouracil results in decreased expression of POU5F1 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G PPA2 inorganic pyrophosphatase 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PPA2 mRNA] CTD PMID:15016801 NCBI chr 4:105,369,077...105,474,070
Ensembl chr 4:105,369,077...105,474,067 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of PPARG protein
PPARG protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPFIBP1 PPFIA binding protein 1 increases expression EXP Fluorouracil results in increased expression of PPFIBP1 mRNA CTD PMID:16510598 NCBI chr12:27,524,206...27,695,564
Ensembl chr12:27,523,431...27,695,564 		JBrowse link
G PPIE peptidylprolyl isomerase E increases expression EXP Fluorouracil results in increased expression of PPIE protein CTD PMID:16803524 NCBI chr 1:39,738,882...39,763,914
Ensembl chr 1:39,692,182...39,763,914 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of PPM1D mRNA; Fluorouracil results in increased expression of PPM1D protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of PPM1D mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of PPM1D mRNA]		 CTD PMID:14665630 PMID:15016801 PMID:17982676 NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha affects response to substance EXP PPP1CA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PPP1CC mRNA] CTD PMID:15016801 NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of PPP1R15A mRNA
PPP1R15A protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 PMID:16709241 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PPP1R17 protein phosphatase 1 regulatory subunit 17 increases expression EXP Fluorouracil results in increased expression of PPP1R17 protein CTD PMID:16803524 NCBI chr 7:31,687,215...31,708,455
Ensembl chr 7:31,687,215...31,708,455 		JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B increases response to substance EXP PPP1R1B protein results in increased susceptibility to Fluorouracil CTD PMID:17470401 NCBI chr17:39,626,707...39,636,624
Ensembl chr17:39,626,740...39,636,626 		JBrowse link
G PPP1R2 protein phosphatase 1 regulatory inhibitor subunit 2 decreases expression EXP Fluorouracil results in decreased expression of PPP1R2 mRNA CTD PMID:16557594 PMID:17039268 NCBI chr 3:195,514,428...195,543,325
Ensembl chr 3:195,514,428...195,543,386 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta increases expression EXP Fluorouracil results in increased expression of PPP2CB mRNA CTD PMID:16709241 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha multiple interactions
increases expression		 EXP [Fluorouracil co-treated with Irinotecan] results in increased expression of PPP3CA mRNA; PPP3CA protein affects the susceptibility to [Fluorouracil co-treated with Irinotecan analog]
Fluorouracil results in increased expression of PPP3CA protein		 CTD PMID:15585135 PMID:16391804 PMID:16803524 PMID:18927307 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PRC1 protein regulator of cytokinesis 1 decreases expression EXP
ISO		 Fluorouracil results in decreased expression of PRC1 mRNA CTD PMID:17374387 PMID:19272435 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629 		JBrowse link
G PRDM14 PR/SET domain 14 affects expression EXP Fluorouracil affects the expression of PRDM14 mRNA CTD PMID:34151400 NCBI chr 8:70,051,651...70,071,252
Ensembl chr 8:70,051,651...70,071,693 		JBrowse link
G PREPL prolyl endopeptidase like multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PREPL mRNA] CTD PMID:15016801 NCBI chr 2:44,317,607...44,361,862
Ensembl chr 2:44,316,281...44,361,862 		JBrowse link
G PRIM1 DNA primase subunit 1 affects response to substance EXP PRIM1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr12:56,731,580...56,752,323
Ensembl chr12:56,730,438...56,752,374 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKAG2 mRNA] CTD PMID:15016801 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214 		JBrowse link
G PRKCI protein kinase C iota multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKCI mRNA] CTD PMID:15016801 NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977 		JBrowse link
G PRKCZ protein kinase C zeta affects expression EXP Fluorouracil affects the expression of PRKCZ mRNA CTD PMID:16584549 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit multiple interactions EXP PRKDC mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKDC mRNA] CTD PMID:15016801 PMID:18546291 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PRNP prion protein (Kanno blood group) decreases response to substance EXP PRNP protein results in decreased susceptibility to Fluorouracil CTD PMID:15386405 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa decreases activity EXP Fluorouracil results in decreased activity of PROC protein CTD PMID:2297659 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PROCR protein C receptor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of PROCR mRNA] CTD PMID:15016801 NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240 		JBrowse link
G PRODH2 proline dehydrogenase 2 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of PRODH2 protein
PRODH2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:35,799,988...35,812,845
Ensembl chr19:35,799,988...35,813,299 		JBrowse link
G PROM1 prominin 1 affects response to substance
increases expression		 EXP PROM1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of PROM1 protein		 CTD PMID:15352031 NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378 		JBrowse link
G PRPF18 pre-mRNA processing factor 18 decreases expression EXP Fluorouracil results in decreased expression of PRPF18 mRNA CTD PMID:16101138 NCBI chr10:13,586,965...13,655,929
Ensembl chr10:13,586,939...13,668,445 		JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 increases expression EXP Fluorouracil results in increased expression of PRPS1 mRNA CTD PMID:16584549 NCBI chr  X:107,628,510...107,651,026
Ensembl chr  X:107,628,428...107,651,993 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 decreases expression EXP Fluorouracil results in decreased expression of PRPS2 mRNA CTD PMID:16510598 NCBI chr  X:12,791,412...12,824,222
Ensembl chr  X:12,791,355...12,824,222 		JBrowse link
G PRR13 proline rich 13 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of PRR13 mRNA CTD PMID:16391804 NCBI chr12:53,441,734...53,446,638
Ensembl chr12:53,441,678...53,446,645 		JBrowse link
G PRRG1 proline rich and Gla domain 1 decreases expression EXP Fluorouracil results in decreased expression of PRRG1 mRNA CTD PMID:17039268 NCBI chr  X:37,349,364...37,457,291
Ensembl chr  X:37,349,309...37,492,702 		JBrowse link
G PRRX1 paired related homeobox 1 decreases expression EXP Fluorouracil results in decreased expression of PRRX1 mRNA CTD PMID:24737281 NCBI chr 1:170,662,768...170,739,421
Ensembl chr 1:170,662,728...170,739,421 		JBrowse link
G PRSS2 serine protease 2 affects expression EXP Fluorouracil affects the expression of PRSS2 mRNA CTD PMID:16584549 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564 		JBrowse link
G PSG9 pregnancy specific beta-1-glycoprotein 9 multiple interactions EXP PSG9 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr19:43,253,282...43,269,530
Ensembl chr19:43,211,791...43,269,530 		JBrowse link
G PSMB10 proteasome 20S subunit beta 10 decreases expression EXP Fluorouracil results in decreased expression of PSMB10 mRNA CTD PMID:16510598 NCBI chr16:67,934,506...67,936,850
Ensembl chr16:67,934,506...67,936,864 		JBrowse link
G PSMC3IP PSMC3 interacting protein affects expression ISO Fluorouracil affects the expression of PSMC3IP mRNA CTD PMID:20421339 NCBI chr17:42,572,310...42,577,831
Ensembl chr17:42,572,310...42,577,831 		JBrowse link
G PSRC1 proline and serine rich coiled-coil 1 decreases expression EXP Fluorouracil results in decreased expression of PSRC1 mRNA CTD PMID:17374387 NCBI chr 1:109,279,556...109,283,145
Ensembl chr 1:109,279,556...109,283,186 		JBrowse link
G PTCH1 patched 1 affects localization
decreases expression
multiple interactions		 EXP Fluorouracil affects the localization of PTCH1 protein
Fluorouracil results in decreased expression of PTCH1 mRNA; Fluorouracil results in decreased expression of PTCH1 protein
[Fluorouracil co-treated with irinotecan] results in increased expression of PTCH1 mRNA; GLI1 protein inhibits the reaction [Fluorouracil affects the localization of PTCH1 protein]		 CTD PMID:16391804 PMID:18776995 PMID:25190613 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G PTEN phosphatase and tensin homolog decreases expression
increases expression		 EXP Fluorouracil results in decreased expression of PTEN mRNA
Fluorouracil results in increased expression of PTEN mRNA		 CTD PMID:17039268 PMID:24737281 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGR1 prostaglandin reductase 1 increases expression EXP Fluorouracil results in increased expression of PTGR1 protein CTD PMID:15585135 PMID:16803524 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
increases response to substance		 EXP
ISO		 [Cisplatin co-treated with Fluorouracil] affects the expression of PTGS2 protein; [Fluorouracil co-treated with Curcumin] results in decreased expression of PTGS2 protein; [Fluorouracil results in increased expression of PTGS2 protein] which results in increased abundance of and results in increased secretion of Dinoprostone; [Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]] which results in decreased abundance of Dinoprostone; acadesine inhibits the reaction [[Fluorouracil results in increased expression of PTGS2 protein] which results in increased abundance of and results in increased secretion of Dinoprostone]; acadesine inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased activity of PTGS2 protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of PTGS2 protein; Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]
Ascorbic Acid inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]; Thymol inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]
Fluorouracil promotes the reaction [resveratrol results in decreased expression of PTGS2 protein]; resveratrol promotes the reaction [Fluorouracil results in decreased expression of PTGS2 protein]
PTGS2 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of PTGS2 mRNA; Fluorouracil results in increased expression of PTGS2 protein
Fluorouracil results in decreased expression of PTGS2 mRNA; Fluorouracil results in decreased expression of PTGS2 protein		 CTD PMID:12414664 PMID:15205334 PMID:15846114 PMID:15896711 PMID:16322294 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 decreases response to substance
decreases phosphorylation
affects expression		 EXP PTK2 protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased phosphorylation of PTK2 protein
Fluorouracil affects the expression of PTK2 mRNA		 CTD PMID:16179862 PMID:34151400 PMID:37625625 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPRK protein tyrosine phosphatase receptor type K affects response to substance EXP PTPRK protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:127,968,785...128,520,599
Ensembl chr 6:127,968,785...128,520,616 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin increases expression
decreases expression
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of PTTG1 protein
Fluorouracil results in decreased expression of PTTG1 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of PTTG1 protein]		 CTD PMID:15016801 PMID:15205334 PMID:16557594 PMID:17039268 PMID:19272435 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G PTTG3P pituitary tumor-transforming 3, pseudogene multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG3P mRNA] CTD PMID:15016801 NCBI chr 8:66,767,329...66,768,034
Ensembl chr 8:66,767,400...66,768,005 		JBrowse link
G PUM1 pumilio RNA binding family member 1 affects expression EXP Fluorouracil affects the expression of PUM1 mRNA CTD PMID:16584549 NCBI chr 1:30,931,506...31,065,717
Ensembl chr 1:30,931,506...31,065,991 		JBrowse link
G PURA purine rich element binding protein A affects expression EXP Fluorouracil affects the expression of PURA mRNA CTD PMID:16584549 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619 		JBrowse link
G PURG purine rich element binding protein G multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of PURG mRNA] CTD PMID:15016801 NCBI chr 8:30,995,802...31,033,356
Ensembl chr 8:30,995,802...31,033,715 		JBrowse link
G PVT1 Pvt1 oncogene decreases expression EXP Fluorouracil results in decreased expression of PVT1 mRNA CTD PMID:16709241 NCBI chr 8:127,794,524...128,101,256
Ensembl chr 8:127,794,513...128,188,202 		JBrowse link
G PWP2 PWP2 small subunit processome component increases expression ISO Fluorouracil results in increased expression of PWP2 mRNA CTD PMID:19272435 NCBI chr21:44,107,399...44,131,181
Ensembl chr21:44,107,373...44,131,181 		JBrowse link
G PXMP2 peroxisomal membrane protein 2 affects expression ISO Fluorouracil affects the expression of PXMP2 mRNA CTD PMID:20421339 NCBI chr12:132,687,587...132,704,985
Ensembl chr12:132,687,587...132,704,985 		JBrowse link
G QSOX1 quiescin sulfhydryl oxidase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of QSOX1 mRNA] CTD PMID:15016801 NCBI chr 1:180,154,869...180,204,030
Ensembl chr 1:180,154,869...180,204,030 		JBrowse link
G R3HDM2 R3H domain containing 2 affects expression EXP Fluorouracil affects the expression of R3HDM2 mRNA CTD PMID:16584549 NCBI chr12:57,253,764...57,431,141
Ensembl chr12:57,253,762...57,431,043 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family decreases expression EXP Fluorouracil results in decreased expression of RAB11A mRNA CTD PMID:17039268 NCBI chr15:65,869,491...65,891,989
Ensembl chr15:65,726,054...65,891,989 		JBrowse link
G RAB20 RAB20, member RAS oncogene family affects response to substance EXP RAB20 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722 		JBrowse link
G RAB21 RAB21, member RAS oncogene family affects expression EXP Fluorouracil affects the expression of RAB21 mRNA CTD PMID:15205334 NCBI chr12:71,754,863...71,800,286
Ensembl chr12:71,754,863...71,800,286 		JBrowse link
G RAB25 RAB25, member RAS oncogene family affects expression ISO Fluorouracil affects the expression of RAB25 mRNA CTD PMID:20421339 NCBI chr 1:156,061,160...156,070,504
Ensembl chr 1:156,061,160...156,070,504 		JBrowse link
G RAB8A RAB8A, member RAS oncogene family decreases expression EXP Fluorouracil results in decreased expression of RAB8A mRNA CTD PMID:16709241 NCBI chr19:16,111,889...16,134,234
Ensembl chr19:16,111,889...16,134,234 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein affects response to substance
increases expression		 EXP RAD23B affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of RAD23B mRNA		 CTD PMID:15067352 PMID:15109396 NCBI chr 9:107,283,279...107,332,194
Ensembl chr 9:107,283,137...107,332,192 		JBrowse link
G RAD51C RAD51 paralog C affects expression ISO Fluorouracil affects the expression of RAD51C mRNA CTD PMID:20421339 NCBI chr17:58,692,573...58,735,611
Ensembl chr17:58,692,573...58,735,611 		JBrowse link
G RAD54B RAD54 homolog B decreases expression EXP Fluorouracil results in decreased expression of RAD54B mRNA CTD PMID:16557594 NCBI chr 8:94,371,960...94,475,115
Ensembl chr 8:94,371,960...94,475,115 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase increases expression
decreases expression		 EXP
ISO		 Fluorouracil results in increased expression of RAF1 mRNA
Fluorouracil results in decreased expression of RAF1 protein		 CTD PMID:15152939 PMID:21296659 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RAMP1 receptor activity modifying protein 1 decreases expression
affects response to substance
multiple interactions		 EXP Fluorouracil results in decreased expression of RAMP1 protein
RAMP1 protein affects the susceptibility to Fluorouracil
RAMP1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]		 CTD PMID:15352031 PMID:16896004 NCBI chr 2:237,858,880...237,912,106
Ensembl chr 2:237,858,893...237,912,106 		JBrowse link
G RANBP1 RAN binding protein 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of RANBP1 mRNA] CTD PMID:15016801 NCBI chr22:20,116,104...20,127,355
Ensembl chr22:20,115,938...20,127,355 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 decreases expression EXP Fluorouracil results in decreased expression of RARRES2 mRNA CTD PMID:16709241 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662 		JBrowse link
G RAX2 retina and anterior neural fold homeobox 2 affects expression EXP Fluorouracil affects the expression of RAX2 mRNA CTD PMID:16584549 NCBI chr19:3,769,089...3,772,228
Ensembl chr19:3,769,089...3,772,228 		JBrowse link
G RB1 RB transcriptional corepressor 1 affects expression
affects response to substance
multiple interactions
increases phosphorylation		 EXP
ISO		 Fluorouracil affects the expression of RB1 mRNA
RB1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of and results in increased phosphorylation of RB1 protein; RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]
RB1 protein affects the susceptibility to Fluorouracil; RB1 protein modified form affects the susceptibility to Fluorouracil
Fluorouracil results in increased phosphorylation of RB1 protein		 CTD PMID:9930367 PMID:15064736 PMID:15205334 PMID:17207318 PMID:17640669 More... NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RBBP4 RB binding protein 4, chromatin remodeling factor decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of RBBP4 mRNA
RBBP4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]		 CTD PMID:16557594 PMID:18678097 NCBI chr 1:32,651,208...32,686,211
Ensembl chr 1:32,651,142...32,686,211 		JBrowse link
G RBM14 RNA binding motif protein 14 increases expression EXP Fluorouracil results in increased expression of RBM14 mRNA CTD PMID:16557594 NCBI chr11:66,616,630...66,629,934
Ensembl chr11:66,616,626...66,629,934 		JBrowse link
G RBM5 RNA binding motif protein 5 affects response to substance EXP RBM5 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:50,088,919...50,119,021
Ensembl chr 3:50,088,919...50,119,021 		JBrowse link
G RBP1 retinol binding protein 1 affects response to substance
decreases expression		 EXP RBP1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of RBP1 protein		 CTD PMID:15352031 NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of RBPJ mRNA CTD PMID:16391804 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RCBTB2 RCC1 and BTB domain containing protein 2 affects expression EXP Fluorouracil affects the expression of RCBTB2 mRNA CTD PMID:16584549 NCBI chr13:48,488,963...48,535,895
Ensembl chr13:48,488,963...48,533,256 		JBrowse link
G RCC1 regulator of chromosome condensation 1 decreases expression EXP Fluorouracil results in decreased expression of RCC1 mRNA CTD PMID:16709241 NCBI chr 1:28,506,043...28,538,989
Ensembl chr 1:28,505,943...28,539,300 		JBrowse link
G RDX radixin affects expression EXP Fluorouracil affects the expression of RDX mRNA CTD PMID:16584549 NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712 		JBrowse link
G RECQL4 RecQ like helicase 4 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of RECQL4 mRNA] CTD PMID:15016801 NCBI chr 8:144,511,288...144,517,833
Ensembl chr 8:144,511,288...144,517,845 		JBrowse link
G REG4 regenerating family member 4 decreases response to substance EXP REG4 protein results in decreased susceptibility to Fluorouracil CTD PMID:17237819 NCBI chr 1:119,794,017...119,811,460
Ensembl chr 1:119,794,017...119,811,580 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
increases phosphorylation
decreases response to substance
affects expression
affects response to substance
decreases expression		 EXP
ISO		 [N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] affects the localization of RELA protein; [N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] results in decreased expression of [NFKB1 protein binds to RELA protein]; Fluorouracil affects the localization of and affects the activity of RELA protein; resveratrol inhibits the reaction [Fluorouracil results in increased phosphorylation of RELA protein]
Bosentan inhibits the reaction [Fluorouracil results in increased expression of RELA protein]; Thymol inhibits the reaction [Fluorouracil results in increased expression of RELA protein]
RELA protein results in decreased susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
Fluorouracil affects the expression of RELA protein
RELA protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of RELA protein		 CTD PMID:12941601 PMID:15548681 PMID:16637064 PMID:16680372 PMID:16724238 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G REPS1 RALBP1 associated Eps domain containing 1 multiple interactions EXP REPS1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr 6:138,903,493...138,988,253
Ensembl chr 6:138,903,493...138,988,261 		JBrowse link
G REST RE1 silencing transcription factor affects expression
decreases expression		 EXP
ISO		 Fluorouracil affects the expression of REST mRNA
Fluorouracil results in decreased expression of REST protein		 CTD PMID:16584549 PMID:21296659 NCBI chr 4:56,907,900...56,935,844
Ensembl chr 4:56,907,876...56,966,808 		JBrowse link
G REV1 REV1 DNA directed polymerase affects expression EXP Fluorouracil affects the expression of REV1 mRNA CTD PMID:16584549 NCBI chr 2:99,400,477...99,490,202
Ensembl chr 2:99,400,475...99,490,035 		JBrowse link
G RFC2 replication factor C subunit 2 affects response to substance EXP RFC2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 7:74,231,502...74,254,399
Ensembl chr 7:74,231,499...74,254,458 		JBrowse link
G RFC3 replication factor C subunit 3 affects response to substance EXP RFC3 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr13:33,818,149...33,977,377
Ensembl chr13:33,818,069...33,966,558 		JBrowse link
G RFC4 replication factor C subunit 4 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of RFC4 mRNA] CTD PMID:15016801 NCBI chr 3:186,789,900...186,806,482
Ensembl chr 3:186,789,880...186,807,058 		JBrowse link
G RGS1 regulator of G protein signaling 1 affects expression EXP Fluorouracil affects the expression of RGS1 mRNA CTD PMID:15205334 NCBI chr 1:192,575,773...192,580,024
Ensembl chr 1:192,575,763...192,580,024 		JBrowse link
G RGS13 regulator of G protein signaling 13 decreases expression EXP Fluorouracil results in decreased expression of RGS13 protein CTD PMID:16803524 NCBI chr 1:192,636,147...192,660,311
Ensembl chr 1:192,636,138...192,660,311 		JBrowse link
G RGS16 regulator of G protein signaling 16 affects expression EXP Fluorouracil affects the expression of RGS16 mRNA CTD PMID:15205334 NCBI chr 1:182,598,623...182,604,389
Ensembl chr 1:182,598,623...182,604,389 		JBrowse link
G RGS2 regulator of G protein signaling 2 decreases expression EXP Fluorouracil results in decreased expression of RGS2 mRNA CTD PMID:16510598 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RGS4 regulator of G protein signaling 4 affects response to substance EXP RGS4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RGS5 regulator of G protein signaling 5 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of RGS5 mRNA
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of RGS5 mRNA]		 CTD PMID:18157009 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791 		JBrowse link
G RHBDL2 rhomboid like 2 affects response to substance EXP RHBDL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:38,885,807...38,941,830
Ensembl chr 1:38,885,807...38,941,830 		JBrowse link
G RHOA ras homolog family member A decreases response to substance EXP RHOA protein results in decreased susceptibility to Fluorouracil CTD PMID:15448013 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression EXP Fluorouracil results in increased expression of RIPK1 mRNA CTD PMID:34151400 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIT1 Ras like without CAAX 1 affects response to substance EXP RIT1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:155,897,808...155,911,349
Ensembl chr 1:155,897,808...155,911,404 		JBrowse link
G RNASE4 ribonuclease A family member 4 affects response to substance EXP RNASE4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216 		JBrowse link
G RND2 Rho family GTPase 2 increases expression EXP Fluorouracil results in increased expression of RND2 mRNA CTD PMID:16101138 NCBI chr17:43,025,231...43,032,041
Ensembl chr17:43,025,231...43,032,041 		JBrowse link
G RNF34 ring finger protein 34 multiple interactions
decreases response to substance		 EXP [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of FAS protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA]; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]
RNF34 protein results in decreased susceptibility to Fluorouracil; RNF34 protein results in decreased susceptibility to Fluorouracil analog		 CTD PMID:16080519 PMID:16270526 PMID:16407826 PMID:16596200 NCBI chr12:121,400,118...121,424,348
Ensembl chr12:121,400,083...121,430,623 		JBrowse link
G RNF4 ring finger protein 4 decreases expression EXP Fluorouracil results in decreased expression of RNF4 mRNA CTD PMID:16709241 NCBI chr 4:2,469,106...2,515,857
Ensembl chr 4:2,462,220...2,515,857 		JBrowse link
G RPL10A ribosomal protein L10a multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of RPL10A mRNA] CTD PMID:15016801 NCBI chr 6:35,468,401...35,470,780
Ensembl chr 6:35,468,401...35,470,785 		JBrowse link
G RPL21P4 ribosomal protein L21 pseudogene 4 increases expression EXP Fluorouracil results in increased expression of RPL21P4 mRNA CTD PMID:16101138 NCBI chr17:43,079,261...43,079,816
Ensembl chr17:43,079,302...43,079,780 		JBrowse link
G RPL23 ribosomal protein L23 increases expression EXP Fluorouracil results in increased expression of RPL23 mRNA CTD PMID:15152939 NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,868,644 		JBrowse link
G RPL23AP1 ribosomal protein L23a pseudogene 1 increases expression EXP Fluorouracil results in increased expression of RPL23AP1 mRNA CTD PMID:16101138 NCBI chr 6:29,726,597...29,727,154
Ensembl chr 6:29,726,669...29,727,139 		JBrowse link
G RPL24 ribosomal protein L24 affects response to substance EXP RPL24 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:101,681,091...101,686,718
Ensembl chr 3:101,681,091...101,686,733 		JBrowse link
G RPL3 ribosomal protein L3 decreases expression EXP Fluorouracil results in decreased expression of RPL3 protein CTD PMID:15585135 PMID:16803524 NCBI chr22:39,312,882...39,319,623
Ensembl chr22:39,312,882...39,320,389 		JBrowse link
G RPL37 ribosomal protein L37 decreases expression EXP Fluorouracil results in decreased expression of RPL37 mRNA CTD PMID:16557594 NCBI chr 5:40,825,262...40,835,222
Ensembl chr 5:40,825,262...40,835,222 		JBrowse link
G RPL6 ribosomal protein L6 decreases response to substance EXP RPL6 protein results in decreased susceptibility to Fluorouracil CTD PMID:15846068 NCBI chr12:112,405,181...112,418,835
Ensembl chr12:112,405,189...112,418,838 		JBrowse link
G RPRD1B regulation of nuclear pre-mRNA domain containing 1B affects response to substance
increases expression		 EXP RPRD1B protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of RPRD1B mRNA		 CTD PMID:15331170 NCBI chr20:38,033,746...38,092,364
Ensembl chr20:38,033,725...38,127,780 		JBrowse link
G RPS26 ribosomal protein S26 affects expression EXP Fluorouracil affects the expression of RPS26 mRNA CTD PMID:16584549 NCBI chr12:56,041,918...56,044,697
Ensembl chr12:56,041,351...56,044,697 		JBrowse link
G RPS27L ribosomal protein S27 like decreases expression
increases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of RPS27L protein
Fluorouracil results in increased expression of RPS27L mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of RPS27L mRNA]		 CTD PMID:15016801 PMID:16557594 PMID:18056458 NCBI chr15:63,148,249...63,157,477
Ensembl chr15:63,125,872...63,158,021 		JBrowse link
G RPS28 ribosomal protein S28 increases expression EXP Fluorouracil results in increased expression of RPS28 mRNA CTD PMID:15152939 NCBI chr19:8,321,496...8,323,340
Ensembl chr19:8,321,158...8,323,340 		JBrowse link
G RRAS RAS related affects response to substance EXP RRAS protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:49,635,292...49,640,143
Ensembl chr19:49,635,292...49,640,143 		JBrowse link
G RRBP1 ribosome binding protein 1 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of RRBP1 protein
RRBP1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr20:17,613,679...17,682,242
Ensembl chr20:17,613,678...17,682,295 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 increases expression EXP Fluorouracil results in increased expression of RRM1 protein CTD PMID:15331170 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 affects expression
affects response to substance
multiple interactions
increases expression
decreases expression		 EXP Fluorouracil affects the expression of RRM2 mRNA
RRM2 protein affects the susceptibility to Fluorouracil
RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fluorouracil results in increased expression of RRM2 mRNA
Fluorouracil results in decreased expression of RRM2 mRNA		 CTD PMID:15205334 PMID:15548681 PMID:16557594 PMID:16584549 PMID:16709241 More... NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases response to substance
increases expression
multiple interactions		 EXP RRM2B protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased expression of RRM2B mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of RRM2B mRNA]		 CTD PMID:15016801 PMID:15890238 PMID:16557594 PMID:21704725 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G RRP15 ribosomal RNA processing 15 homolog decreases expression EXP Fluorouracil results in decreased expression of RRP15 mRNA CTD PMID:16510598 NCBI chr 1:218,285,293...218,337,983
Ensembl chr 1:218,285,293...218,337,983 		JBrowse link
G RSRC2 arginine and serine rich coiled-coil 2 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of RSRC2 mRNA
RSRC2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 NCBI chr12:122,503,454...122,526,936
Ensembl chr12:122,503,454...122,527,000 		JBrowse link
G RTKN rhotekin multiple interactions
decreases response to substance		 EXP Curcumin inhibits the reaction [RTKN protein results in decreased susceptibility to Fluorouracil] CTD PMID:15480428 NCBI chr 2:74,425,835...74,441,937
Ensembl chr 2:74,425,835...74,442,422 		JBrowse link
G RTL8C retrotransposon Gag like 8C affects response to substance EXP RTL8C protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:135,032,355...135,033,546
Ensembl chr  X:135,032,355...135,033,546 		JBrowse link
G RUNX2 RUNX family transcription factor 2 affects expression ISO Fluorouracil affects the expression of RUNX2 mRNA CTD PMID:24704097 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G S100A10 S100 calcium binding protein A10 increases expression EXP Fluorouracil results in increased expression of S100A10 mRNA CTD PMID:16557594 NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859 		JBrowse link
G S100A11 S100 calcium binding protein A11 increases expression
increases response to substance
multiple interactions		 ISO
EXP		 Fluorouracil results in increased expression of S100A11 mRNA
S100A11 mutant form results in increased susceptibility to Fluorouracil
[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased expression of H2AX protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein]; S100A11 mutant form promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]		 CTD PMID:19272435 PMID:25940438 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G S100A2 S100 calcium binding protein A2 affects expression
increases expression
multiple interactions
affects response to substance
decreases expression		 EXP Fluorouracil affects the expression of S100A2 mRNA
Fluorouracil results in increased expression of S100A2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of S100A2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of S100A2 mRNA]
S100A2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of S100A2 protein		 CTD PMID:15016801 PMID:15352031 PMID:16584549 PMID:17982676 NCBI chr 1:153,561,108...153,565,844
Ensembl chr 1:153,561,108...153,567,890 		JBrowse link
G S100A3 S100 calcium binding protein A3 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of S100A3 protein
S100A3 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 1:153,547,329...153,549,258
Ensembl chr 1:153,547,329...153,549,258 		JBrowse link
G S100A4 S100 calcium binding protein A4 affects response to substance
decreases expression		 EXP S100A4 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of S100A4 protein		 CTD PMID:15352031 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G S100P S100 calcium binding protein P decreases expression
increases response to substance
affects response to substance		 EXP Fluorouracil results in decreased expression of S100P protein
S100P protein results in increased susceptibility to Fluorouracil
S100P protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:18636193 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170 		JBrowse link
G SAA1 serum amyloid A1 increases expression EXP Fluorouracil results in increased expression of SAA1 mRNA CTD PMID:16101138 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 affects expression EXP Fluorouracil affects the expression of SAMHD1 mRNA CTD PMID:16584549 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893 		JBrowse link
G SAP30 Sin3A associated protein 30 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAP30 mRNA] CTD PMID:15016801 NCBI chr 4:173,370,954...173,377,532
Ensembl chr 4:173,369,969...173,377,532 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 multiple interactions
increases expression
decreases response to substance		 EXP [Fluorouracil co-treated with N(1),N(11)-diethylnorspermine] results in increased expression of SAT1 mRNA; [Fluorouracil co-treated with N(1),N(11)-diethylnorspermine] results in increased expression of SAT1 protein; [N(1), N(12)-diethylspermine co-treated with Fluorouracil] results in increased activity of SAT1 protein; [N(1),N(11)-diethylnorspermine co-treated with Fluorouracil] results in increased expression of SAT1 mRNA; TP53 protein affects the reaction [Fluorouracil results in increased expression of SAT1 mRNA]
SAT1 mRNA results in decreased susceptibility to Fluorouracil		 CTD PMID:15152939 PMID:16510598 PMID:16557594 PMID:16637064 PMID:17237273 More... NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210 		JBrowse link
G SCAMP3 secretory carrier membrane protein 3 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of SCAMP3 mRNA CTD PMID:16391804 NCBI chr 1:155,255,981...155,262,360
Ensembl chr 1:155,255,979...155,262,433 		JBrowse link
G SCCPDH saccharopine dehydrogenase (putative) increases expression EXP Fluorouracil results in increased expression of SCCPDH mRNA CTD PMID:16101138 NCBI chr 1:246,724,409...246,768,137
Ensembl chr 1:246,724,409...246,768,137 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression
affects response to substance
multiple interactions
decreases expression		 EXP Fluorouracil results in increased expression of SCD mRNA
SCD protein affects the susceptibility to Fluorouracil
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of SCD mRNA]		 CTD PMID:16217747 PMID:17039268 PMID:17982676 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SCG2 secretogranin II decreases expression
increases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of SCG2 protein
Fluorouracil results in increased expression of SCG2 mRNA
SCG2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:24737281 NCBI chr 2:223,596,940...223,602,361
Ensembl chr 2:223,596,940...223,602,361 		JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 affects expression EXP Fluorouracil affects the expression of SCN2B mRNA CTD PMID:16584549 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of SCNN1A protein
SCNN1A protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta affects expression EXP Fluorouracil affects the expression of SCNN1B mRNA CTD PMID:16584549 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCUBE2 signal peptide, CUB domain and EGF like domain containing 2 multiple interactions EXP SCUBE2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:9,019,476...9,091,599
Ensembl chr11:9,019,476...9,138,114 		JBrowse link
G SDCCAG8 SHH signaling and ciliogenesis regulator SDCCAG8 increases expression EXP Fluorouracil results in increased expression of SDCCAG8 mRNA CTD PMID:16510598 NCBI chr 1:243,256,041...243,500,091
Ensembl chr 1:243,256,034...243,500,091 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A affects response to substance EXP SDHA protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SDHD succinate dehydrogenase complex subunit D affects expression EXP Fluorouracil affects the expression of SDHD mRNA CTD PMID:34151400 NCBI chr11:112,086,873...112,095,794
Ensembl chr11:112,086,824...112,120,016 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 affects response to substance EXP SEC14L1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:77,088,685...77,217,101
Ensembl chr17:77,088,749...77,217,101 		JBrowse link
G SEC23A SEC23 homolog A, COPII coat complex component affects response to substance EXP SEC23A protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:39,031,919...39,103,235
Ensembl chr14:39,031,919...39,109,646 		JBrowse link
G SEC31A SEC31 homolog A, COPII coat complex component affects response to substance EXP SEC31A protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:82,818,509...82,900,569
Ensembl chr 4:82,818,509...82,901,166 		JBrowse link
G SEC31B SEC31 homolog B, COPII coat complex component multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SEC31B mRNA] CTD PMID:15016801 NCBI chr10:100,486,647...100,519,861
Ensembl chr10:100,486,646...100,519,864 		JBrowse link
G SELENOP selenoprotein P multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SELENOP mRNA] CTD PMID:15016801 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392 		JBrowse link
G SEMA3A semaphorin 3A increases expression EXP Fluorouracil results in increased expression of SEMA3A mRNA CTD PMID:16510598 NCBI chr 7:83,955,777...84,492,725
Ensembl chr 7:83,955,777...84,492,724 		JBrowse link
G SEPHS1 selenophosphate synthetase 1 affects response to substance EXP SEPHS1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:13,317,428...13,348,293
Ensembl chr10:13,317,428...13,348,298 		JBrowse link
G SEPHS2 selenophosphate synthetase 2 affects response to substance EXP SEPHS2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:30,443,631...30,445,874
Ensembl chr16:30,443,631...30,445,874 		JBrowse link
G SEPTIN9 septin 9 affects expression ISO Fluorouracil affects the expression of SEPTIN9 mRNA CTD PMID:20421339 NCBI chr17:77,281,499...77,500,596
Ensembl chr17:77,280,569...77,500,596 		JBrowse link
G SERF2 small EDRK-rich factor 2 decreases expression EXP Fluorouracil results in decreased expression of SERF2 mRNA CTD PMID:16510598 NCBI chr15:43,777,086...43,796,089
Ensembl chr15:43,777,087...43,804,427 		JBrowse link
G SERPINA5 serpin family A member 5 increases expression EXP Fluorouracil results in increased expression of SERPINA5 mRNA CTD PMID:17039268 NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118 		JBrowse link
G SERPINA7 serpin family A member 7 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPINA7 mRNA] CTD PMID:15016801 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727 		JBrowse link
G SERPINB2 serpin family B member 2 increases expression EXP Fluorouracil results in increased expression of SERPINB2 mRNA CTD PMID:16709241 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888 		JBrowse link
G SERPINB4 serpin family B member 4 decreases expression EXP Fluorouracil results in decreased expression of SERPINB4 protein CTD PMID:16803524 NCBI chr18:63,637,259...63,644,256
Ensembl chr18:63,637,259...63,644,256 		JBrowse link
G SERPINB5 serpin family B member 5 multiple interactions
increases response to substance
increases expression		 EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of SERPINB5 mRNA; TP53 protein affects the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]
SERPINB5 protein results in increased susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:16331619 PMID:16391804 PMID:17982676 NCBI chr18:63,476,958...63,505,085
Ensembl chr18:63,476,958...63,505,085 		JBrowse link
G SERPIND1 serpin family D member 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPIND1 mRNA] CTD PMID:15016801 NCBI chr22:20,774,113...20,787,720
Ensembl chr22:20,774,113...20,787,720 		JBrowse link
G SERPINE2 serpin family E member 2 multiple interactions EXP SERPINE2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318 		JBrowse link
G SERPINI1 serpin family I member 1 increases expression EXP Fluorouracil results in increased expression of SERPINI1 mRNA CTD PMID:24737281 NCBI chr 3:167,735,721...167,825,569
Ensembl chr 3:167,735,243...167,825,569 		JBrowse link
G SERTAD1 SERTA domain containing 1 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of SERTAD1 mRNA] CTD PMID:15016801 PMID:16557594 PMID:16584549 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992 		JBrowse link
G SESN1 sestrin 1 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SESN1 mRNA]
Fluorouracil results in increased expression of SESN1 mRNA; Fluorouracil results in increased expression of SESN1 protein		 CTD PMID:14665630 PMID:15016801 PMID:17982676 PMID:22525470 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846 		JBrowse link
G SESN2 sestrin 2 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN2 mRNA] CTD PMID:15016801 PMID:22525470 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491 		JBrowse link
G SET SET nuclear proto-oncogene decreases expression ISO Fluorouracil results in decreased expression of SET mRNA CTD PMID:19272435 NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400 		JBrowse link
G SETD5 SET domain containing 5 affects expression EXP Fluorouracil affects the expression of SETD5 mRNA CTD PMID:16584549 NCBI chr 3:9,397,615...9,478,154
Ensembl chr 3:9,397,615...9,479,240 		JBrowse link
G SEZ6L seizure related 6 homolog like multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SEZ6L mRNA] CTD PMID:15016801 NCBI chr22:26,169,462...26,383,596
Ensembl chr22:26,169,462...26,383,597 		JBrowse link
G SF3B3 splicing factor 3b subunit 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SF3B3 mRNA] CTD PMID:15016801 NCBI chr16:70,523,816...70,577,668
Ensembl chr16:70,523,791...70,577,670 		JBrowse link
G SFN stratifin multiple interactions
increases expression
affects expression		 EXP SFN protein affects the susceptibility to [Fluorouracil co-treated with Cisplatin]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SFN mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SFN mRNA]
Fluorouracil affects the expression of SFN mRNA		 CTD PMID:15016801 PMID:15999354 PMID:16557594 PMID:16584549 PMID:17982676 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression EXP Fluorouracil results in decreased expression of SFRP2 mRNA CTD PMID:24737281 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SGCE sarcoglycan epsilon affects response to substance EXP SGCE protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:94,584,980...94,656,133
Ensembl chr 7:94,524,204...94,656,572 		JBrowse link
G SHH sonic hedgehog signaling molecule decreases expression
increases expression		 EXP
ISO		 Fluorouracil results in decreased expression of SHH mRNA
Fluorouracil results in increased expression of SHH mRNA		 CTD PMID:18776995 PMID:26272751 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SHISA9 shisa family member 9 increases expression EXP Fluorouracil results in increased expression of SHISA9 mRNA CTD PMID:24737281 NCBI chr16:12,901,598...13,563,017
Ensembl chr16:12,901,598...13,240,416 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SHMT2 mRNA] CTD PMID:15016801 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935 		JBrowse link
G SIGLEC1 sialic acid binding Ig like lectin 1 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of SIGLEC1 mRNA CTD PMID:16391804 NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600 		JBrowse link
G SIGLEC9 sialic acid binding Ig like lectin 9 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SIGLEC9 mRNA] CTD PMID:15016801 NCBI chr19:51,119,778...51,136,263
Ensembl chr19:51,124,906...51,136,651 		JBrowse link
G SIRT4 sirtuin 4 increases expression EXP Fluorouracil results in increased expression of SIRT4 mRNA; Fluorouracil results in increased expression of SIRT4 protein CTD PMID:39241941 NCBI chr12:120,291,780...120,313,249
Ensembl chr12:120,302,316...120,313,249 		JBrowse link
G SKIC8 SKI8 subunit of superkiller complex multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SKIC8 mRNA] CTD PMID:15016801 NCBI chr15:78,283,235...78,299,609
Ensembl chr15:78,277,835...78,299,703 		JBrowse link
G SLC13A5 solute carrier family 13 member 5 decreases response to substance EXP SLC13A5 protein results in decreased susceptibility to Fluorouracil CTD PMID:32634519 NCBI chr17:6,684,719...6,713,369
Ensembl chr17:6,684,719...6,713,377 		JBrowse link
G SLC15A1 solute carrier family 15 member 1 decreases activity
decreases expression		 EXP Fluorouracil results in decreased activity of SLC15A1 protein
Fluorouracil results in decreased expression of SLC15A1 mRNA		 CTD PMID:16253763 NCBI chr13:98,683,801...98,752,672
Ensembl chr13:98,683,801...98,752,672 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 decreases expression EXP Fluorouracil results in decreased expression of SLC16A1 mRNA CTD PMID:16709241 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 decreases expression
affects response to substance
increases expression		 EXP Fluorouracil results in decreased expression of SLC16A6 protein
SLC16A6 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of SLC16A6 mRNA		 CTD PMID:15352031 PMID:16510598 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 increases transport EXP SLC22A7 protein results in increased transport of Fluorouracil CTD PMID:15901346 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 increases transport ISO SLC22A8 protein results in increased transport of Fluorouracil CTD PMID:15100168 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC25A23 solute carrier family 25 member 23 affects expression EXP Fluorouracil affects the expression of SLC25A23 mRNA CTD PMID:16584549 NCBI chr19:6,436,081...6,459,792
Ensembl chr19:6,436,079...6,465,203 		JBrowse link
G SLC25A27 solute carrier family 25 member 27 decreases expression EXP Fluorouracil results in decreased expression of SLC25A27 mRNA CTD PMID:34151400 NCBI chr 6:46,652,975...46,678,190
Ensembl chr 6:46,652,915...46,678,190 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) multiple interactions
decreases response to substance
affects response to substance
increases expression		 EXP 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in decreased susceptibility to Fluorouracil]; Fluorouracil promotes the reaction [SLC29A1 protein results in increased uptake of Gemcitabine]
SLC29A1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of SLC29A1; Fluorouracil results in increased expression of SLC29A1 mRNA		 CTD PMID:16217747 PMID:16868479 PMID:17695509 PMID:18383843 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 decreases expression
decreases activity
increases expression		 EXP Fluorouracil results in decreased expression of SLC2A1 mRNA
Fluorouracil results in decreased activity of SLC2A1 protein
Fluorouracil results in increased expression of SLC2A1 mRNA		 CTD PMID:16253763 PMID:16595493 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A14 solute carrier family 2 member 14 affects response to substance EXP SLC2A14 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:7,812,514...7,891,196
Ensembl chr12:7,812,512...7,891,148 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions
increases expression		 ISO Fluorouracil promotes the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]; Phloretin inhibits the reaction [Fluorouracil promotes the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]]
Fluorouracil results in increased expression of SLC2A2 mRNA; Fluorouracil results in increased expression of SLC2A2 protein		 CTD PMID:15986457 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 affects response to substance EXP SLC2A3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC35F5 solute carrier family 35 member F5 affects response to substance EXP SLC35F5 protein affects the susceptibility to Fluorouracil CTD PMID:16477629 NCBI chr 2:113,702,682...113,756,642
Ensembl chr 2:113,705,011...113,756,693 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 increases expression
affects response to substance		 EXP Fluorouracil results in increased expression of SLC3A2 mRNA
SLC3A2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SLC47A1 solute carrier family 47 member 1 affects response to substance EXP SLC47A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034 		JBrowse link
G SLC48A1 solute carrier family 48 member 1 affects expression EXP Fluorouracil affects the expression of SLC48A1 mRNA CTD PMID:16584549 NCBI chr12:47,753,934...47,782,751
Ensembl chr12:47,753,916...47,782,751 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 increases expression ISO Fluorouracil results in increased expression of SLC5A1 protein CTD PMID:15986457 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 decreases expression EXP Fluorouracil results in decreased expression of SLC9A3 mRNA CTD PMID:34151400 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G SLCO2A1 solute carrier organic anion transporter family member 2A1 affects expression EXP Fluorouracil affects the expression of SLCO2A1 mRNA CTD PMID:16584549 NCBI chr 3:133,932,701...134,029,925
Ensembl chr 3:133,932,701...134,052,184 		JBrowse link
G SMAD4 SMAD family member 4 multiple interactions EXP SMAD4 results in decreased susceptibility to [Fluorouracil co-treated with alpha-Tocopherol] CTD PMID:20562578 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMARCA1 SNF2 related chromatin remodeling ATPase 1 affects response to substance
increases expression		 EXP SMARCA1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of SMARCA1 protein		 CTD PMID:15352031 PMID:16217747 NCBI chr  X:129,446,506...129,523,490
Ensembl chr  X:129,446,501...129,523,500 		JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 increases expression EXP Fluorouracil results in increased expression of SMCHD1 mRNA CTD PMID:16510598 NCBI chr18:2,655,726...2,805,017
Ensembl chr18:2,655,726...2,805,017 		JBrowse link
G SMIM10L2A small integral membrane protein 10 like 2A decreases expression EXP Fluorouracil results in decreased expression of SMIM10L2A mRNA CTD PMID:34151400 NCBI chr  X:135,421,944...135,428,075
Ensembl chr  X:135,421,944...135,428,075 		JBrowse link
G SMIM14 small integral membrane protein 14 increases expression EXP Fluorouracil results in increased expression of SMIM14 mRNA CTD PMID:16510598 NCBI chr 4:39,546,336...39,638,865
Ensembl chr 4:39,546,336...39,638,902 		JBrowse link
G SMN2 survival of motor neuron 2, centromeric decreases expression EXP Fluorouracil results in decreased expression of SMN2 mRNA CTD PMID:16101138 NCBI chr 5:70,049,523...70,090,528
Ensembl chr 5:70,049,638...70,078,522
Ensembl chr 5:70,049,638...70,078,522 		JBrowse link
G SMO smoothened, frizzled class receptor decreases expression EXP Fluorouracil results in decreased expression of SMO mRNA; Fluorouracil results in decreased expression of SMO protein CTD PMID:18776995 PMID:25190613 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G SMOX spermine oxidase multiple interactions EXP [oxaliplatin co-treated with Fluorouracil] results in increased expression of and results in increased activity of SMOX protein; [oxaliplatin co-treated with Fluorouracil] results in increased expression of SMOX mRNA CTD PMID:17987291 NCBI chr20:4,148,828...4,187,727
Ensembl chr20:4,120,980...4,187,747 		JBrowse link
G SMS spermine synthase increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of SMS mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of SMS mRNA]		 CTD PMID:15016801 PMID:15152939 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 increases expression EXP Fluorouracil results in increased expression of SMURF1 mRNA CTD PMID:16557594 NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of SNAI2 protein
resveratrol inhibits the reaction [Fluorouracil results in increased expression of SNAI2 protein]		 CTD PMID:26310874 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G SNAP29 synaptosome associated protein 29 increases expression EXP Fluorouracil results in increased expression of SNAP29 protein CTD PMID:16803524 NCBI chr22:20,859,007...20,891,214
Ensembl chr22:20,859,007...20,891,214 		JBrowse link
G SNAPC1 small nuclear RNA activating complex polypeptide 1 decreases expression EXP Fluorouracil results in decreased expression of SNAPC1 protein CTD PMID:15585135 PMID:16803524 NCBI chr14:61,762,420...61,796,428
Ensembl chr14:61,762,420...61,796,428 		JBrowse link
G SNHG15 small nucleolar RNA host gene 15 affects expression
affects response to substance		 EXP Fluorouracil affects the expression of SNHG15 protein
SNHG15 protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 NCBI chr 7:44,983,023...44,986,696
Ensembl chr 7:44,983,019...44,986,961 		JBrowse link
G SNORD22 small nucleolar RNA, C/D box 22 increases expression EXP Fluorouracil results in increased expression of SNORD22 mRNA CTD PMID:17039268 NCBI chr11:62,852,910...62,853,035
Ensembl chr11:62,852,910...62,853,035 		JBrowse link
G SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 decreases expression EXP Fluorouracil results in decreased expression of SNRNP48 mRNA CTD PMID:16510598 NCBI chr 6:7,590,198...7,611,967
Ensembl chr 6:7,590,198...7,611,967 		JBrowse link
G SNRPA1 small nuclear ribonucleoprotein polypeptide A' multiple interactions EXP SNRPA1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr15:101,281,510...101,295,248
Ensembl chr15:101,281,510...101,295,282 		JBrowse link
G SNTB1 syntrophin beta 1 increases expression EXP Fluorouracil results in increased expression of SNTB1 mRNA CTD PMID:16510598 NCBI chr 8:120,535,756...120,812,046
Ensembl chr 8:120,535,745...120,813,273 		JBrowse link
G SNX6 sorting nexin 6 affects response to substance EXP SNX6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:34,561,093...34,630,148
Ensembl chr14:34,561,093...34,630,160 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 affects response to substance EXP SOAT1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:179,293,797...179,358,680
Ensembl chr 1:179,293,714...179,358,680 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 increases expression EXP Fluorouracil results in increased expression of SOCS1 mRNA CTD PMID:16557594 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression
decreases activity
multiple interactions		 ISO Fluorouracil results in increased expression of SOD1 protein
Fluorouracil results in decreased activity of SOD1 protein
casticin promotes the reaction [Fluorouracil results in increased expression of SOD1 protein]; Fluorouracil promotes the reaction [casticin results in increased expression of SOD1 protein]		 CTD PMID:29117755 PMID:32270916 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [irinotecan co-treated with Fluorouracil] results in increased activity of SOD2 protein CTD PMID:15886469 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX17 SRY-box transcription factor 17 decreases expression
decreases localization		 ISO
EXP		 Fluorouracil results in decreased expression of SOX17 protein
Fluorouracil results in decreased expression of SOX17 mRNA
Fluorouracil results in decreased localization of SOX17 protein		 CTD PMID:21296659 PMID:24154490 PMID:24737281 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SOX18 SRY-box transcription factor 18 affects response to substance EXP SOX18 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:64,047,582...64,049,639
Ensembl chr20:64,047,582...64,049,639 		JBrowse link
G SOX2 SRY-box transcription factor 2 decreases expression ISO Fluorouracil results in decreased expression of SOX2 protein CTD PMID:21296659 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SOX4 SRY-box transcription factor 4 increases expression EXP Fluorouracil results in increased expression of SOX4 mRNA CTD PMID:16510598 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions EXP Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; SP1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:15489892 PMID:18927307 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SP3 Sp3 transcription factor multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SP3 mRNA] CTD PMID:15016801 NCBI chr 2:173,900,775...173,965,702
Ensembl chr 2:173,880,850...173,965,373 		JBrowse link
G SPAG5 sperm associated antigen 5 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SPAG5 mRNA] CTD PMID:15016801 NCBI chr17:28,577,574...28,599,025
Ensembl chr17:28,577,565...28,599,025 		JBrowse link
G SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1 affects response to substance EXP SPANXA1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:141,583,674...141,584,738
Ensembl chr  X:141,583,674...141,584,738 		JBrowse link
G SPANXC SPANX family member C affects response to substance EXP SPANXC protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:141,241,463...141,242,517
Ensembl chr  X:141,241,463...141,242,517 		JBrowse link
G SPARC secreted protein acidic and cysteine rich multiple interactions
affects expression
increases response to substance		 EXP
ISO		 [decitabine affects the methylation of SPARC promoter] which affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of SPARC mRNA
SPARC protein results in increased susceptibility to Fluorouracil		 CTD PMID:15902309 PMID:18458674 PMID:24704097 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975 		JBrowse link
G SPATA25 spermatogenesis associated 25 increases expression EXP Fluorouracil results in increased expression of SPATA25 protein CTD PMID:15331170 NCBI chr20:45,886,491...45,891,016
Ensembl chr20:45,886,491...45,887,622 		JBrowse link
G SPINK4 serine peptidase inhibitor Kazal type 4 affects expression EXP Fluorouracil affects the expression of SPINK4 mRNA CTD PMID:16584549 NCBI chr 9:33,240,167...33,248,567
Ensembl chr 9:33,218,365...33,248,567 		JBrowse link
G SPN sialophorin multiple interactions EXP Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 increases expression EXP Fluorouracil results in increased expression of SPOCK1 mRNA CTD PMID:24737281 NCBI chr 5:136,975,298...137,499,326
Ensembl chr 5:136,975,298...137,598,379 		JBrowse link
G SPON1 spondin 1 affects expression EXP Fluorouracil affects the expression of SPON1 mRNA CTD PMID:15205334 NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,723...14,268,133 		JBrowse link
G SPRR1A small proline rich protein 1A increases expression EXP Fluorouracil results in increased expression of SPRR1A mRNA CTD PMID:16584549 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814 		JBrowse link
G SPRR1B small proline rich protein 1B affects expression EXP Fluorouracil affects the expression of SPRR1B mRNA CTD PMID:16584549 NCBI chr 1:153,031,203...153,032,900
Ensembl chr 1:153,031,203...153,032,900 		JBrowse link
G SPRR3 small proline rich protein 3 affects expression EXP Fluorouracil affects the expression of SPRR3 mRNA CTD PMID:16584549 NCBI chr 1:153,001,749...153,003,856
Ensembl chr 1:153,001,747...153,003,856 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 increases expression EXP Fluorouracil results in increased expression of SPRY1 mRNA CTD PMID:17039268 NCBI chr 4:123,396,795...123,403,760
Ensembl chr 4:123,396,795...123,403,760 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 increases expression EXP Fluorouracil results in increased expression of SPTAN1 mRNA CTD PMID:34151400 NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662 		JBrowse link
G SQLE squalene epoxidase decreases expression EXP Fluorouracil results in decreased expression of SQLE mRNA CTD PMID:15205334 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase increases phosphorylation
decreases expression
affects response to substance		 EXP Fluorouracil results in increased phosphorylation of SRC protein
Fluorouracil results in decreased expression of SRC protein
SRC protein affects the susceptibility to Fluorouracil		 CTD PMID:18794807 PMID:39334374 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 affects expression EXP Fluorouracil affects the expression of SREBF1 mRNA CTD PMID:34151400 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 decreases expression EXP Fluorouracil results in decreased expression of SREBF2 mRNA CTD PMID:34151400 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G SRI sorcin decreases response to substance EXP SRI protein results in decreased susceptibility to Fluorouracil CTD PMID:18423116 NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,115...88,226,993 		JBrowse link
G SRP19 signal recognition particle 19 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of SRP19 mRNA CTD PMID:16391804 NCBI chr 5:112,861,287...112,898,371
Ensembl chr 5:112,861,188...112,898,371 		JBrowse link
G SRP72 signal recognition particle 72 increases expression EXP Fluorouracil results in increased expression of SRP72 mRNA CTD PMID:16584549 NCBI chr 4:56,467,617...56,503,681
Ensembl chr 4:56,467,617...56,503,681 		JBrowse link
G SRP9 signal recognition particle 9 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SRP9 mRNA] CTD PMID:15016801 NCBI chr 1:225,777,826...225,790,464
Ensembl chr 1:225,777,813...225,790,468 		JBrowse link
G SRRM1 serine and arginine repetitive matrix 1 decreases expression EXP Fluorouracil results in decreased expression of SRRM1 mRNA CTD PMID:16709241 NCBI chr 1:24,643,302...24,673,281
Ensembl chr 1:24,631,716...24,673,281 		JBrowse link
G SRSF11 serine and arginine rich splicing factor 11 increases expression EXP Fluorouracil results in increased expression of SRSF11 protein CTD PMID:15331170 NCBI chr 1:70,205,696...70,253,052
Ensembl chr 1:70,205,682...70,253,052 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of SRSF6 mRNA] CTD PMID:15016801 NCBI chr20:43,457,896...43,464,243
Ensembl chr20:43,457,893...43,466,046 		JBrowse link
G SST somatostatin increases expression ISO Fluorouracil results in increased expression of SST protein CTD PMID:21296659 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G STARD7 StAR related lipid transfer domain containing 7 affects expression EXP Fluorouracil affects the expression of STARD7 mRNA CTD PMID:16584549 NCBI chr 2:96,184,859...96,208,827
Ensembl chr 2:96,184,859...96,208,827 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 increases expression EXP Fluorouracil results in increased expression of STAT1 mRNA CTD PMID:34151400 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression
affects response to substance
decreases phosphorylation		 EXP Fluorouracil results in increased expression of STAT3 mRNA
STAT3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased phosphorylation of STAT3 protein		 CTD PMID:15682485 PMID:15730734 PMID:16557594 PMID:18161298 PMID:18205257 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAU1 staufen double-stranded RNA binding protein 1 decreases expression EXP Fluorouracil results in decreased expression of STAU1 mRNA CTD PMID:16709241 NCBI chr20:49,113,339...49,219,295
Ensembl chr20:49,113,339...49,188,367 		JBrowse link
G STBD1 starch binding domain 1 affects response to substance EXP STBD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:76,306,733...76,311,130
Ensembl chr 4:76,306,733...76,311,130 		JBrowse link
G STK38 serine/threonine kinase 38 affects response to substance EXP STK38 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:36,493,892...36,547,479
Ensembl chr 6:36,493,892...36,547,479 		JBrowse link
G STK4 serine/threonine kinase 4 multiple interactions EXP STK4 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr20:44,966,512...45,080,021
Ensembl chr20:44,966,494...45,084,214 		JBrowse link
G STOM stomatin decreases expression EXP Fluorouracil results in decreased expression of STOM mRNA CTD PMID:24737281 NCBI chr 9:121,338,987...121,370,250
Ensembl chr 9:121,338,987...121,370,304 		JBrowse link
G STX5 syntaxin 5 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of STX5 mRNA CTD PMID:16391804 NCBI chr11:62,806,860...62,832,051
Ensembl chr11:62,806,860...62,832,051 		JBrowse link
G STXBP4 syntaxin binding protein 4 affects expression ISO Fluorouracil affects the expression of STXBP4 mRNA CTD PMID:20421339 NCBI chr17:54,968,765...55,213,273
Ensembl chr17:54,968,727...55,173,632 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling decreases expression EXP Fluorouracil results in decreased expression of SUFU mRNA CTD PMID:18776995 NCBI chr10:102,502,819...102,633,535
Ensembl chr10:102,503,972...102,633,535 		JBrowse link
G SUPV3L1 Suv3 like RNA helicase decreases expression EXP Fluorouracil results in decreased expression of SUPV3L1 mRNA CTD PMID:17039268 NCBI chr10:69,180,234...69,209,093
Ensembl chr10:69,180,234...69,209,099 		JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 decreases expression EXP Fluorouracil results in decreased expression of SWAP70 mRNA CTD PMID:16510598 NCBI chr11:9,664,077...9,752,993
Ensembl chr11:9,664,077...9,752,993 		JBrowse link
G SYCP3 synaptonemal complex protein 3 decreases expression ISO Fluorouracil results in decreased expression of SYCP3 protein CTD PMID:21296659 NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472 		JBrowse link
G SYMPK symplekin scaffold protein decreases expression EXP Fluorouracil results in decreased expression of SYMPK mRNA CTD PMID:16709241 NCBI chr19:45,815,410...45,863,147
Ensembl chr19:45,815,410...45,863,225 		JBrowse link
G SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein decreases expression EXP Fluorouracil results in decreased expression of SYNCRIP mRNA CTD PMID:17039268 NCBI chr 6:85,607,784...85,643,870
Ensembl chr 6:85,607,779...85,644,063 		JBrowse link
G SYP synaptophysin increases expression ISO Fluorouracil results in increased expression of SYP protein CTD PMID:21296659 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,218 		JBrowse link
G SYTL2 synaptotagmin like 2 increases expression EXP Fluorouracil results in increased expression of SYTL2 mRNA CTD PMID:16510598 NCBI chr11:85,694,229...85,854,870
Ensembl chr11:85,694,224...85,811,159 		JBrowse link
G TAF3 TATA-box binding protein associated factor 3 affects expression EXP Fluorouracil affects the expression of TAF3 mRNA CTD PMID:16584549 NCBI chr10:7,818,505...8,016,631
Ensembl chr10:7,818,497...8,016,631 		JBrowse link
G TAF5L TATA-box binding protein associated factor 5 like multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of TAF5L mRNA CTD PMID:16391804 NCBI chr 1:229,593,134...229,626,122
Ensembl chr 1:229,593,134...229,626,122 		JBrowse link
G TAGLN transgelin decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of TAGLN protein
TAGLN protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16217747 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TANK TRAF family member associated NFKB activator increases expression EXP Fluorouracil results in increased expression of TANK protein CTD PMID:16803524 NCBI chr 2:161,136,963...161,236,230
Ensembl chr 2:161,136,908...161,236,230 		JBrowse link
G TAOK3 TAO kinase 3 affects response to substance EXP TAOK3 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr12:118,149,801...118,372,907
Ensembl chr12:118,149,801...118,372,907 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member multiple interactions
increases expression		 EXP TP53 protein promotes the reaction [Fluorouracil results in increased expression of TAP1 mRNA] CTD PMID:17982676 PMID:20737486 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member increases expression EXP Fluorouracil results in increased expression of TAP2 mRNA CTD PMID:20737486 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TAT tyrosine aminotransferase decreases expression ISO Fluorouracil results in decreased expression of TAT protein CTD PMID:21296659 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092 		JBrowse link
G TAX1BP3 Tax1 binding protein 3 increases expression EXP Fluorouracil results in increased expression of TAX1BP3 mRNA CTD PMID:16709241 NCBI chr17:3,662,895...3,668,578
Ensembl chr17:3,662,895...3,668,679 		JBrowse link
G TBCD tubulin folding cofactor D multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TBCD mRNA] CTD PMID:15016801 NCBI chr17:82,752,065...82,945,914
Ensembl chr17:82,752,042...82,945,914 		JBrowse link
G TBCE tubulin folding cofactor E affects response to substance EXP TBCE protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:235,367,427...235,452,443
Ensembl chr 1:235,367,360...235,452,443 		JBrowse link
G TBRG4 transforming growth factor beta regulator 4 increases expression ISO Fluorouracil results in increased expression of TBRG4 mRNA CTD PMID:19272435 NCBI chr 7:45,100,100...45,111,697
Ensembl chr 7:45,100,100...45,112,047 		JBrowse link
G TBXT T-box transcription factor T decreases expression ISO Fluorouracil results in decreased expression of T protein CTD PMID:21296659 NCBI chr 6:166,157,656...166,168,655
Ensembl chr 6:166,157,656...166,168,700 		JBrowse link
G TCF15 transcription factor 15 increases expression EXP Fluorouracil results in increased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr20:604,257...610,309
Ensembl chr20:604,257...610,309 		JBrowse link
G TCF19 transcription factor 19 affects response to substance
increases expression		 EXP TCF19 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of TCF19 mRNA		 CTD PMID:15331170 NCBI chr 6:31,158,589...31,164,215
Ensembl chr 6:31,158,331...31,167,159 		JBrowse link
G TCF3 transcription factor 3 affects expression EXP Fluorouracil affects the expression of TCF3 mRNA CTD PMID:34151400 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,291...1,652,615 		JBrowse link
G TCF7L2 transcription factor 7 like 2 multiple interactions
decreases expression		 EXP
ISO		 TCF7L2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]
[HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC1 protein]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC2 protein]; TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]; TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]
Fluorouracil results in decreased expression of TCF7L2 mRNA; Fluorouracil results in decreased expression of TCF7L2 protein		 CTD PMID:18678097 PMID:25178657 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
G TEK TEK receptor tyrosine kinase increases expression ISO Fluorouracil results in increased expression of TEK mRNA CTD PMID:15817675 NCBI chr 9:27,109,225...27,230,174
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TERF2 telomeric repeat binding factor 2 increases expression EXP Fluorouracil results in increased expression of TERF2 protein CTD PMID:15585135 PMID:16803524 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571 		JBrowse link
G TERT telomerase reverse transcriptase multiple interactions
decreases expression
affects response to substance
decreases response to substance
decreases activity		 EXP
ISO		 [Fluorouracil co-treated with Gemcitabine] results in decreased activity of TERT protein; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TERT mRNA]
Fluorouracil results in decreased expression of TERT protein
TERT protein affects the susceptibility to Fluorouracil
TERT mRNA results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of TERT mRNA; Fluorouracil results in decreased expression of TERT mRNA alternative form; Fluorouracil results in decreased expression of TERT protein modified form
Fluorouracil results in decreased activity of TERT protein		 CTD PMID:15003732 PMID:15016801 PMID:15608686 PMID:16455633 PMID:16929163 More... NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFCP2L1 transcription factor CP2 like 1 increases expression ISO Fluorouracil results in increased expression of TFCP2L1 protein CTD PMID:21296659 NCBI chr 2:121,216,587...121,285,202
Ensembl chr 2:121,216,587...121,285,202 		JBrowse link
G TFDP1 transcription factor Dp-1 decreases expression EXP Fluorouracil results in decreased expression of TFDP1 mRNA CTD PMID:16510598 PMID:34151400 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473 		JBrowse link
G TFF1 trefoil factor 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TFF1 mRNA] CTD PMID:15016801 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TFPI tissue factor pathway inhibitor affects response to substance EXP TFPI protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G TFRC transferrin receptor multiple interactions
increases expression		 EXP
ISO		 TP53 protein affects the reaction [Fluorouracil results in decreased expression of TFRC mRNA]
Fluorouracil results in increased expression of TFRC protein
ferrostatin-1 inhibits the reaction [Fluorouracil results in increased expression of TFRC protein]		 CTD PMID:15016801 PMID:35101590 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFA transforming growth factor alpha multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of TGFA mRNA] CTD PMID:15016801 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression
multiple interactions
affects response to substance		 EXP
ISO		 Fluorouracil results in increased expression of TGFB1 mRNA
[Fluorouracil co-treated with TGFB1 protein] results in increased expression of MT2A mRNA; TGFB1 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]
Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 protein]
Fluorouracil results in increased expression of TGFB1 mRNA; Fluorouracil results in increased expression of TGFB1 protein
TGFB1 protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16557594 PMID:16888818 PMID:18344199 PMID:28507149 More... NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB2 transforming growth factor beta 2 affects response to substance
decreases response to substance		 EXP
ISO		 TGFB2 protein affects the susceptibility to Fluorouracil
TGFB2 gene polymorphism results in decreased susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:18941179 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TGFBI transforming growth factor beta induced affects response to substance EXP TGFBI protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 increases expression EXP Fluorouracil results in increased expression of TGFBR3 mRNA CTD PMID:16557594 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335 		JBrowse link
G TH tyrosine hydroxylase affects expression ISO Fluorouracil affects the expression of TH protein CTD PMID:21296659 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G THBS1 thrombospondin 1 multiple interactions
affects response to substance
affects expression
increases expression		 EXP EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 mRNA]; EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 protein]; Fluorouracil promotes the reaction [EGR1 protein binds to THBS1 promoter]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of THBS1 mRNA]
THBS1 protein affects the susceptibility to Fluorouracil
Fluorouracil affects the expression of THBS1 mRNA
Fluorouracil results in increased expression of THBS1 mRNA; Fluorouracil results in increased expression of THBS1 protein		 CTD PMID:15205334 PMID:16217747 PMID:18757417 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G THNSL2 threonine synthase like 2 multiple interactions EXP THNSL2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:88,170,346...88,186,627
Ensembl chr 2:88,170,295...88,186,636 		JBrowse link
G THOC1 THO complex subunit 1 decreases expression EXP Fluorouracil results in decreased expression of THOC1 mRNA CTD PMID:16709241 NCBI chr18:214,520...268,047
Ensembl chr18:214,520...268,050 		JBrowse link
G THSD7A thrombospondin type 1 domain containing 7A increases expression EXP Fluorouracil results in increased expression of THSD7A mRNA CTD PMID:24737281 NCBI chr 7:11,370,365...11,832,198
Ensembl chr 7:11,370,365...11,832,198 		JBrowse link
G TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 affects response to substance EXP TIAL1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr10:119,573,465...119,596,964
Ensembl chr10:119,571,802...119,597,029 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of TIGAR mRNA] CTD PMID:15016801 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G TIMELESS timeless circadian regulator affects response to substance EXP TIMELESS protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr12:56,416,363...56,449,426
Ensembl chr12:56,416,363...56,449,426 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 increases expression EXP Fluorouracil results in increased expression of TIMP3 mRNA CTD PMID:24737281 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 decreases expression ISO Fluorouracil results in decreased expression of TINF2 mRNA CTD PMID:19272435 NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,238,286...24,242,663 		JBrowse link
G TJP3 tight junction protein 3 affects expression EXP Fluorouracil affects the expression of TJP3 mRNA CTD PMID:16584549 NCBI chr19:3,708,384...3,750,813
Ensembl chr19:3,708,362...3,750,813 		JBrowse link
G TK1 thymidine kinase 1 affects expression
affects response to substance
multiple interactions		 EXP Fluorouracil affects the expression of TK1 mRNA
TK1 protein affects the susceptibility to Fluorouracil
Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA]		 CTD PMID:15374632 PMID:15548681 PMID:16557594 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TK2 thymidine kinase 2 increases expression EXP Fluorouracil results in increased expression of TK2 mRNA CTD PMID:19219653 NCBI chr16:66,508,003...66,550,291
Ensembl chr16:66,508,003...66,552,544 		JBrowse link
G TLR3 toll like receptor 3 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of TLR3 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of TLR3 mRNA]		 CTD PMID:18779317 PMID:20367642 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of TLR4 protein
Bosentan inhibits the reaction [Fluorouracil results in increased expression of TLR4 protein]		 CTD PMID:34800596 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 increases secretion
multiple interactions		 ISO Fluorouracil results in increased secretion of TLR9 protein
Hydroxychloroquine inhibits the reaction [Fluorouracil results in increased secretion of TLR9 protein]		 CTD PMID:32314717 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TMEM150C transmembrane protein 150C decreases expression EXP Fluorouracil results in decreased expression of TMEM150C mRNA CTD PMID:24737281 NCBI chr 4:82,483,176...82,562,253
Ensembl chr 4:82,483,170...82,562,357 		JBrowse link
G TMEM184B transmembrane protein 184B affects response to substance EXP TMEM184B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:38,216,395...38,273,010
Ensembl chr22:38,219,291...38,273,010 		JBrowse link
G TMEM187 transmembrane protein 187 decreases expression EXP Fluorouracil results in decreased expression of TMEM187 mRNA CTD PMID:34151400 NCBI chr  X:153,972,754...153,983,194
Ensembl chr  X:153,972,754...153,983,194 		JBrowse link
G TMEM33 transmembrane protein 33 decreases expression EXP Fluorouracil results in decreased expression of TMEM33 mRNA CTD PMID:16510598 NCBI chr 4:41,935,137...41,960,803
Ensembl chr 4:41,935,129...41,960,803 		JBrowse link
G TMEM40 transmembrane protein 40 affects expression EXP Fluorouracil affects the expression of TMEM40 mRNA CTD PMID:16584549 NCBI chr 3:12,733,528...12,769,457
Ensembl chr 3:12,733,528...12,769,457 		JBrowse link
G TMEM74 transmembrane protein 74 increases expression EXP Fluorouracil results in increased expression of TMEM74 mRNA CTD PMID:16510598 NCBI chr 8:108,606,850...108,787,594
Ensembl chr 8:108,606,850...108,787,594 		JBrowse link
G TMEM9B TMEM9 domain family member B affects expression ISO Fluorouracil affects the expression of TMEM9B mRNA CTD PMID:20421339 NCBI chr11:8,947,202...8,964,947
Ensembl chr11:8,947,202...8,965,011 		JBrowse link
G TMSB10 thymosin beta 10 increases expression EXP Fluorouracil results in increased expression of TMSB10 mRNA CTD PMID:15152939 NCBI chr 2:84,905,656...84,906,671
Ensembl chr 2:84,905,656...84,906,671 		JBrowse link
G TMSB15A thymosin beta 15A affects response to substance EXP TMSB15A affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr  X:102,513,682...102,516,739
Ensembl chr  X:102,513,682...102,516,739 		JBrowse link
G TMSB4X thymosin beta 4 X-linked increases expression EXP Fluorouracil results in increased expression of TMSB4X mRNA CTD PMID:15152939 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227 		JBrowse link
G TMSB4XP6 TMSB4X pseudogene 6 affects response to substance EXP TMSB4XP6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:50,840,219...50,840,824
Ensembl chr20:50,840,615...50,840,749 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 TNF promoter polymorphism affects the susceptibility to [Fluorouracil co-treated with Cisplatin]
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of TNF protein
Fluorouracil inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TNF protein]; Silybin inhibits the reaction [Fluorouracil results in increased expression of TNF protein]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF protein]
Fluorouracil results in increased expression of TNF mRNA; Fluorouracil results in increased expression of TNF protein		 CTD PMID:16820919 PMID:18344199 PMID:18523641 PMID:18535404 PMID:25824412 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 increases expression EXP Fluorouracil results in increased expression of TNFAIP3 mRNA CTD PMID:16557594 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of TNFRSF10A mRNA; Fluorouracil results in increased expression of TNFRSF10A protein
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TNFRSF10A mRNA		 CTD PMID:15585621 PMID:26544897 PMID:32800223 PMID:34151400 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b multiple interactions
increases expression		 EXP [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TNFRSF10B mRNA; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFRSF10B mRNA]
Fluorouracil results in increased expression of TNFRSF10B mRNA; Fluorouracil results in increased expression of TNFRSF10B protein		 CTD PMID:15585621 PMID:17982676 PMID:26544897 PMID:32800223 PMID:34151400 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c increases expression EXP Fluorouracil results in increased expression of TNFRSF10C protein CTD PMID:15585621 NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,921...23,117,445 		JBrowse link
G TNFRSF10D TNF receptor superfamily member 10d increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of TNFRSF10D protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of TNFRSF10D mRNA]		 CTD PMID:15016801 PMID:15585621 NCBI chr 8:23,135,588...23,164,027
Ensembl chr 8:23,135,588...23,164,027 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b increases expression EXP Fluorouracil results in increased expression of TNFRSF11B mRNA CTD PMID:16557594 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF18 TNF receptor superfamily member 18 increases expression EXP Fluorouracil results in increased expression of TNFRSF18 mRNA CTD PMID:16557594 NCBI chr 1:1,203,508...1,206,592
Ensembl chr 1:1,203,508...1,206,592 		JBrowse link
G TNFRSF19 TNF receptor superfamily member 19 decreases expression EXP Fluorouracil results in decreased expression of TNFRSF19 mRNA CTD PMID:24737281 NCBI chr13:23,570,412...23,676,093
Ensembl chr13:23,570,370...23,676,104 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A affects expression EXP Fluorouracil affects the expression of TNFRSF1A mRNA CTD PMID:34151400 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B affects response to substance EXP TNFRSF1B protein affects the susceptibility to Fluorouracil CTD PMID:16477629 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF10 TNF superfamily member 10 multiple interactions
affects expression
increases expression
increases activity
increases response to substance
increases abundance		 EXP
ISO		 [Fluorouracil co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [Fluorouracil results in decreased expression of CFLAR protein] which results in increased susceptibility to TNFSF10 protein; CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]; CFLAR protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 protein]; XIAP protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]
Fluorouracil affects the expression of TNFSF10 mRNA
TNFSF10 results in increased abundance of Fluorouracil
Fluorouracil results in increased expression of TNFSF10 mRNA; Fluorouracil results in increased expression of TNFSF10 protein		 CTD PMID:11750847 PMID:15120327 PMID:16373718 PMID:19106633 PMID:20876774 More... NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNFSF13 TNF superfamily member 13 increases expression EXP Fluorouracil results in increased expression of TNFSF13 mRNA CTD PMID:18423122 PMID:20003335 NCBI chr17:7,558,282...7,561,601
Ensembl chr17:7,558,292...7,561,608 		JBrowse link
G TNNI1 troponin I1, slow skeletal type increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of TNNI1 protein
Bosentan inhibits the reaction [Fluorouracil results in increased expression of TNNI1 protein]		 CTD PMID:34800596 NCBI chr 1:201,403,784...201,421,730
Ensembl chr 1:201,403,784...201,429,866 		JBrowse link
G TNNI3 troponin I3, cardiac type decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of TNNI3 protein
TNNI3 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773 		JBrowse link
G TNNT1 troponin T1, slow skeletal type decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of TNNT1 protein
TNNT1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206 		JBrowse link
G TNS3 tensin 3 affects response to substance EXP TNS3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:47,275,154...47,582,586
Ensembl chr 7:47,275,154...47,582,558 		JBrowse link
G TOB1 transducer of ERBB2, 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of TOB1 mRNA] CTD PMID:15016801 NCBI chr17:50,862,223...50,867,978
Ensembl chr17:50,862,223...50,867,978 		JBrowse link
G TOP1 DNA topoisomerase I affects response to substance
decreases expression		 EXP TOP1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of TOP1 mRNA		 CTD PMID:16709241 PMID:18509181 NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487 		JBrowse link
G TOP2A DNA topoisomerase II alpha decreases expression
multiple interactions		 EXP
ISO		 Fluorouracil results in decreased expression of TOP2A mRNA
TOP2A protein affects the susceptibility to [Cyclophosphamide co-treated with Epirubicin co-treated with Fluorouracil]; TOP2A protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TOP2A mRNA]		 CTD PMID:15016801 PMID:15205334 PMID:16557594 PMID:16682728 PMID:18465341 More... NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 affects response to substance EXP TOPBP1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:133,600,238...133,661,941
Ensembl chr 3:133,598,175...133,662,380 		JBrowse link
G TP53 tumor protein p53 multiple interactions
affects activity
increases acetylation
affects phosphorylation
increases phosphorylation
decreases response to substance
decreases expression
increases expression
increases response to substance
increases activity
affects response to substance
decreases degradation		 EXP
ISO		 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TP53 mRNA; [CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; [Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA; [Fluorouracil co-treated with olaparib] results in increased expression of TP53 protein; [Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; [nutlin 3 results in increased stability of TP53 protein] which results in increased susceptibility to Fluorouracil; [TP53 affects the expression of TYMS] which affects the susceptibility to Fluorouracil; anacardic acid inhibits the reaction [[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the phosphorylation of TP53 protein]; Cadmium Chloride affects the reaction [Fluorouracil results in increased expression of TP53 mRNA]; Cadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]; Cycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]; Fluorouracil affects the reaction [Cadmium Chloride affects the phosphorylation of TP53 protein]; Fluorouracil affects the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein]; Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; Fluorouracil promotes the reaction [allose results in increased expression of TP53 protein]; Fluorouracil promotes the reaction [andrographolide results in increased expression of TP53]; Fluorouracil promotes the reaction [TP53 protein binds to CES2 intron]; Fluorouracil promotes the reaction [TP53 protein mutant form binds to UBE2C promoter]; Fluorouracil results in increased expression of and results in increased phosphorylation of TP53 protein; Fluorouracil results in increased phosphorylation of and results in increased activity of TP53 protein; Genistein promotes the reaction [Fluorouracil results in increased expression of TP53 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of TP53 protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of TP53 protein]; TP53 affects the reaction [Resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]; TP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]]; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACTL8 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GYG2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AX mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H4C2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of IFI16 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of INPP5E mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of IQGAP2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ITPR1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of KCNQ2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF15 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF23 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of KLF5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of KPNA2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of L1TD1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of LDHA mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of LRBA mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of LYPLA1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MACF1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MAP4K5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MARS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM6 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM7 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of METAP2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MMP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of MMS19 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NASP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NBN mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NCAPG mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NEK2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NIPSNAP2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NR1D2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of NUCKS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ODC1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of OXCT1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PAFAH1B1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PAIP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PDCD1LG2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PFN2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PGLYRP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PHIP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PI4KB mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PLK1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PMF1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PMS2P4 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PPA2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PPP1CC mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PREPL mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKAG2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKCI mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKDC mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG3P mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of PURG mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of QSOX1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of RANBP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of RECQL4 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of RFC4 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of RPL10A mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAP30 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SEC31B mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SELENOP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPINA7 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPIND1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SEZ6L mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SF3B3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SHMT2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SIGLEC9 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SKIC8 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SMS mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SP3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SPAG5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SRP9 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of SRSF6 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TBCD mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TERT mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TFF1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TFRC mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TOP2A mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TRAP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TROAP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TSPO mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TUBA4B mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNIP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNRD3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2S mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of UGT8 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of UQCRB mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of USH2A mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of VANGL2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of WARS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of WEE1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of WTAP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of YARS1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZIM2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZMYND8 mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZNF266 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CNK mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of ID2B mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of IER5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of INKA2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of NINJ1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of PLK2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of PMAIP1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of PPM1D mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of PROCR mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of RPS27L mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of RRM2B mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of S100A2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SAT1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SERTAD1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SESN2 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of SFN mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TGFA mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TIGAR mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TLR3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TNFRSF10D mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TOB1 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA]; TP53 protein affects the susceptibility to [Fluorouracil co-treated with Cisplatin]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of SCD mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of VEGFA mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of PLK1 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of PTTG1 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]; TP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in decreased expression of MYC mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of IKBIP mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of PLK2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of PPM1D mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of S100A2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SESN1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of SFN mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TAP1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFRSF10B mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TRIAP1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of ZMAT3 mRNA]; TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]; TP53 protein results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]; TP53 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]; TP53 results in increased susceptibility to [Poly I-C co-treated with Fluorouracil]
Fluorouracil affects the activity of TP53 protein
Fluorouracil promotes the reaction [Luteolin results in increased expression of TRP53 protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of TRP53 protein]
TP53 promoter mutant form results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of TP53 mRNA
TRP53 results in increased susceptibility to Fluorouracil
Fluorouracil results in increased activity of TRP53 protein
Fluorouracil results in increased expression of TP53 protein; Fluorouracil results in increased expression of TRP53 protein
ferrostatin-1 inhibits the reaction [Fluorouracil results in increased expression of TRP53 protein]; Fluorouracil promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]
TP53 protein results in increased susceptibility to Fluorouracil; TP53 results in increased susceptibility to Fluorouracil
TP53 gene polymorphism affects the susceptibility to Fluorouracil; TP53 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of TP53; Fluorouracil results in increased expression of TP53 mRNA; Fluorouracil results in increased expression of TP53 protein; Fluorouracil results in increased expression of TP53 protein modified form
Fluorouracil results in increased activity of TP53 protein		 CTD PMID:9050858 PMID:9192825 PMID:11750847 PMID:12082016 PMID:12792779 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 multiple interactions EXP Fluorouracil promotes the reaction [IFNA1 protein results in increased expression of TP53AIP1 mRNA] CTD PMID:17971768 NCBI chr11:128,934,731...128,942,871
Ensembl chr11:128,934,731...128,943,399 		JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 increases expression
multiple interactions
affects response to substance		 EXP Fluorouracil results in increased expression of TP53I3 mRNA; Fluorouracil results in increased expression of TP53I3 protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]
TP53I3 protein affects the susceptibility to Fluorouracil		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16217747 PMID:16557594 More... NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861 		JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 multiple interactions
increases expression		 EXP TP53 protein affects the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA] CTD PMID:15016801 PMID:16510598 PMID:16557594 PMID:17039268 PMID:17982676 NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378 		JBrowse link
G TP73 tumor protein p73 affects response to substance
multiple interactions		 EXP TP73 protein affects the susceptibility to Fluorouracil
TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA]		 CTD PMID:18714155 PMID:21127500 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
G TPI1 triosephosphate isomerase 1 decreases expression
affects response to substance		 EXP Fluorouracil results in decreased expression of TPI1 mRNA
TPI1 protein affects the susceptibility to Fluorouracil		 CTD PMID:16510598 PMID:18309519 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TPM1 tropomyosin 1 affects response to substance EXP TPM1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TPMT thiopurine S-methyltransferase multiple interactions EXP TPMT protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077 		JBrowse link
G TPP1 tripeptidyl peptidase 1 affects expression EXP Fluorouracil affects the expression of TPP1 mRNA CTD PMID:16584549 NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448 		JBrowse link
G TPP2 tripeptidyl peptidase 2 affects localization EXP
ISO		 Fluorouracil affects the localization of TPP2 protein CTD PMID:20643100 NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958 		JBrowse link
G TPST2 tyrosylprotein sulfotransferase 2 affects response to substance EXP TPST2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:26,521,996...26,590,132
Ensembl chr22:26,521,996...26,596,717 		JBrowse link
G TPT1 tumor protein, translationally-controlled 1 decreases response to substance EXP TPT1 protein results in decreased susceptibility to Fluorouracil CTD PMID:15262975 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284 		JBrowse link
G TRADD TNFRSF1A associated via death domain affects expression EXP Fluorouracil affects the expression of TRADD mRNA CTD PMID:34151400 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TRAF2 TNF receptor associated factor 2 decreases expression EXP Fluorouracil results in decreased expression of TRAF2 CTD PMID:10891390 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRAP1 TNF receptor associated protein 1 multiple interactions
affects expression		 EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TRAP1 mRNA]
Fluorouracil affects the expression of TRAP1 mRNA		 CTD PMID:15016801 PMID:34151400 NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553 		JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of TRIAP1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of TRIAP1 mRNA]		 CTD PMID:17982676 NCBI chr12:120,443,964...120,446,384
Ensembl chr12:120,443,964...120,446,384 		JBrowse link
G TRIB2 tribbles pseudokinase 2 increases expression EXP Fluorouracil results in increased expression of TRIB2 mRNA CTD PMID:16510598 NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734 		JBrowse link
G TRIB3 tribbles pseudokinase 3 affects expression EXP Fluorouracil affects the expression of TRIB3 mRNA CTD PMID:16584549 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TRIM2 tripartite motif containing 2 affects response to substance EXP TRIM2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319 		JBrowse link
G TRIOBP TRIO and F-actin binding protein affects response to substance EXP TRIOBP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr22:37,697,048...37,776,556
Ensembl chr22:37,697,048...37,776,556 		JBrowse link
G TROAP trophinin associated protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TROAP mRNA] CTD PMID:15016801 NCBI chr12:49,323,255...49,331,731
Ensembl chr12:49,323,236...49,331,731 		JBrowse link
G TSC2 TSC complex subunit 2 increases expression EXP Fluorouracil results in increased expression of TSC2 mRNA CTD PMID:16584549 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TSHB thyroid stimulating hormone subunit beta affects expression EXP Fluorouracil affects the expression of TSHB protein CTD PMID:17649788 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302 		JBrowse link
G TSHZ1 teashirt zinc finger homeobox 1 increases expression EXP Fluorouracil results in increased expression of TSHZ1 mRNA CTD PMID:16584549 NCBI chr18:75,210,797...75,289,944
Ensembl chr18:75,210,755...75,289,950 		JBrowse link
G TSPAN8 tetraspanin 8 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in decreased expression of TSPAN8 mRNA CTD PMID:16391804 NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898 		JBrowse link
G TSPO translocator protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TSPO mRNA] CTD PMID:15016801 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G TSR1 TSR1 ribosome maturation factor decreases expression EXP Fluorouracil results in decreased expression of TSR1 mRNA CTD PMID:16510598 NCBI chr17:2,322,396...2,336,457
Ensembl chr17:2,322,396...2,336,657 		JBrowse link
G TST thiosulfate sulfurtransferase affects response to substance EXP TST protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183 		JBrowse link
G TTYH2 tweety family member 2 decreases expression EXP Fluorouracil results in decreased expression of TTYH2 mRNA CTD PMID:16510598 NCBI chr17:74,213,571...74,262,020
Ensembl chr17:74,213,571...74,262,020 		JBrowse link
G TUBA4B tubulin alpha 4b multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TUBA4B mRNA] CTD PMID:15016801 NCBI chr 2:219,253,243...219,272,197
Ensembl chr 2:219,253,243...219,272,197 		JBrowse link
G TUBA8 tubulin alpha 8 decreases expression EXP Fluorouracil results in decreased expression of TUBA8 mRNA CTD PMID:17039268 NCBI chr22:18,110,809...18,131,732
Ensembl chr22:18,110,100...18,146,683 		JBrowse link
G TUBB tubulin beta class I decreases expression EXP Fluorouracil results in decreased expression of TUBB mRNA CTD PMID:17039268 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538 		JBrowse link
G TUBB2A tubulin beta 2A class IIa decreases expression EXP Fluorouracil results in decreased expression of TUBB2A mRNA CTD PMID:33770205 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544 		JBrowse link
G TUBB3 tubulin beta 3 class III decreases expression ISO Fluorouracil results in decreased expression of TUBB3 mRNA CTD PMID:19272435 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G TUBB4B tubulin beta 4B class IVb affects response to substance EXP TUBB4B protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707 		JBrowse link
G TUBD1 tubulin delta 1 affects response to substance EXP TUBD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:59,859,479...59,892,943
Ensembl chr17:59,859,426...59,892,945 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions
affects response to substance
increases expression		 EXP [allose co-treated with Fluorouracil] results in increased expression of TXNIP protein; Fluorouracil promotes the reaction [allose results in increased expression of TXNIP mRNA]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNIP mRNA]
TXNIP protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of TXNIP mRNA		 CTD PMID:15016801 PMID:15548681 PMID:18930000 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G TXNRD1 thioredoxin reductase 1 decreases expression
decreases activity		 EXP
ISO		 Fluorouracil results in decreased expression of TXNRD1 mRNA
Fluorouracil results in decreased activity of TXNRD1 protein		 CTD PMID:19219653 PMID:31288002 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G TXNRD3 thioredoxin reductase 3 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNRD3 mRNA] CTD PMID:15016801 NCBI chr 3:126,607,050...126,655,124
Ensembl chr 3:126,571,779...126,655,124 		JBrowse link
G TYMP thymidine phosphorylase multiple interactions
affects response to substance
decreases response to substance
decreases expression		 EXP
ISO		 [Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein; [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to Fluorouracil; acetylleucyl-leucyl-norleucinal inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; TYMP mRNA affects the susceptibility to [Irinotecan co-treated with Fluorouracil co-treated with Leucovorin]
TYMP protein affects the susceptibility to Fluorouracil
TYMP mRNA results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of TYMP mRNA		 CTD PMID:15041737 PMID:15301717 PMID:15538739 PMID:15655543 PMID:16160472 More... NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G TYMS thymidylate synthetase multiple interactions
decreases expression
decreases activity
increases expression
increases response to substance
affects response to substance
decreases response to substance
increases activity
affects expression		 EXP
ISO		 [Arsenic Trioxide co-treated with Fluorouracil co-treated with Leucovorin] results in decreased expression of TYMS mRNA; [Cisplatin co-treated with Fluorouracil] results in decreased expression of TYMS mRNA; [Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein; [SU 9516 results in decreased expression of TYMS] which results in increased susceptibility to Fluorouracil; [TP53 affects the expression of TYMS] which affects the susceptibility to Fluorouracil; [trichostatin A results in decreased expression of TYMS protein] which results in increased susceptibility to Fluorouracil; [wogonin co-treated with Fluorouracil] results in increased expression of TYMS mRNA; acetylleucyl-leucyl-norleucinal inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Fluorouracil results in increased expression of TYMS protein]; Docetaxel inhibits the reaction [Fluorouracil results in increased activity of TYMS protein]; Docetaxel inhibits the reaction [Fluorouracil results in increased expression of TYMS mRNA]; Fluorouracil inhibits the reaction [[Doxorubicin co-treated with Paclitaxel] results in decreased expression of TYMS protein]; Fluorouracil promotes the reaction [Docetaxel results in decreased expression of TYMS protein]; Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA]; gambogic acid inhibits the reaction [Fluorouracil results in increased expression of TYMS mRNA]; TYMS 3' UTR polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; TYMS gene polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; TYMS gene polymorphism results in decreased susceptibility to [Fluorouracil co-treated with Cisplatin]; TYMS gene polymorphism results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with Cisplatin co-treated with Paclitaxel]; TYMS mRNA affects the susceptibility to [Irinotecan co-treated with Fluorouracil co-treated with Leucovorin]; TYMS promoter polymorphism results in increased susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin co-treated with Docetaxel]; TYMS protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin]
Fluorouracil results in decreased expression of TYMS protein
[Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate; [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid; Leucovorin promotes the reaction [Fluorouracil results in decreased expression of TYMS]; Thymidine inhibits the reaction [Fluorouracil results in decreased expression of TYMS]
Fluorouracil results in increased expression of TYMS mRNA; Fluorouracil results in increased expression of TYMS protein
TYMS gene polymorphism results in increased susceptibility to Fluorouracil; TYMS mRNA results in increased susceptibility to Fluorouracil; TYMS protein results in increased susceptibility to Fluorouracil; TYMS results in increased susceptibility to Fluorouracil
TYMS affects the susceptibility to Fluorouracil; TYMS gene polymorphism affects the susceptibility to Fluorouracil; TYMS mRNA affects the susceptibility to Fluorouracil; TYMS promoter polymorphism affects the susceptibility to Fluorouracil; TYMS protein affects the susceptibility to Fluorouracil; TYMS protein affects the susceptibility to Fluorouracil analog
TYMS 3' UTR mutant form results in decreased susceptibility to Fluorouracil; TYMS 5' UTR polymorphism results in decreased susceptibility to Fluorouracil; TYMS gene polymorphism results in decreased susceptibility to Fluorouracil; TYMS mRNA results in decreased susceptibility to Fluorouracil; TYMS protein results in decreased susceptibility to Fluorouracil; TYMS results in decreased susceptibility to Fluorouracil
Fluorouracil affects the expression of TYMS mRNA; Fluorouracil affects the expression of TYMS protein		 CTD PMID:2537495 PMID:7763285 PMID:8060136 PMID:9050858 PMID:9299594 More... NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G TYRP1 tyrosinase related protein 1 decreases expression EXP Fluorouracil results in decreased expression of TYRP1 mRNA CTD PMID:24737281 NCBI chr 9:12,693,385...12,710,285
Ensembl chr 9:12,685,439...12,710,285 		JBrowse link
G U2SURP U2 snRNP associated SURP domain containing decreases expression EXP Fluorouracil results in decreased expression of U2SURP mRNA CTD PMID:16510598 NCBI chr 3:143,001,570...143,060,725
Ensembl chr 3:142,964,497...143,060,725 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C decreases expression
multiple interactions		 EXP Fluorouracil results in decreased expression of UBE2C mRNA; Fluorouracil results in decreased expression of UBE2C protein
[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; anacardic acid inhibits the reaction [[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein]; CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; CDKN1A protein affects the reaction [Fluorouracil results in decreased expression of UBE2C protein]; Fluorouracil inhibits the reaction [NFYA protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [EP300 protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]; Fluorouracil promotes the reaction [TP53 protein mutant form binds to UBE2C promoter]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C protein]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]]; TP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]]		 CTD PMID:16557594 PMID:17039268 PMID:17374387 PMID:27129209 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957 		JBrowse link
G UBE2S ubiquitin conjugating enzyme E2 S multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2S mRNA] CTD PMID:15016801 NCBI chr19:55,399,745...55,407,788
Ensembl chr19:55,399,745...55,407,788 		JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T affects expression EXP Fluorouracil affects the expression of UBE2T mRNA CTD PMID:16557594 NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 affects response to substance EXP UCHL1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G UCK2 uridine-cytidine kinase 2 affects response to substance
decreases expression		 EXP UCK2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of UCK2 mRNA		 CTD PMID:15548681 PMID:19219653 NCBI chr 1:165,827,614...165,911,618
Ensembl chr 1:165,827,614...165,911,618 		JBrowse link
G UCP2 uncoupling protein 2 decreases expression EXP Fluorouracil results in decreased expression of UCP2 mRNA CTD PMID:34151400 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843 		JBrowse link
G UGDH UDP-glucose 6-dehydrogenase affects response to substance EXP UGDH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:39,498,755...39,527,439
Ensembl chr 4:39,498,755...39,528,311 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP UGT1A1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with irinotecan] CTD PMID:18797458 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT8 UDP glycosyltransferase 8 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of UGT8 mRNA] CTD PMID:15016801 NCBI chr 4:114,598,402...114,678,225
Ensembl chr 4:114,598,770...114,678,588 		JBrowse link
G UMPS uridine monophosphate synthetase multiple interactions
decreases response to substance
affects response to substance
increases response to substance		 EXP [docetaxel co-treated with Fluorouracil] results in increased expression of UMPS mRNA; Fluorouracil inhibits the reaction [wogonin results in decreased expression of UMPS mRNA]; Fluorouracil promotes the reaction [docetaxel results in increased expression of UMPS protein]; Fluorouracil promotes the reaction [gambogic acid results in increased expression of UMPS mRNA]
UMPS protein results in decreased susceptibility to Fluorouracil
UMPS affects the susceptibility to Fluorouracil; UMPS mRNA affects the susceptibility to Fluorouracil; UMPS protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased susceptibility to UMPS protein		 CTD PMID:15548681 PMID:16477629 PMID:16557585 PMID:16757204 PMID:17237621 More... NCBI chr 3:124,730,452...124,749,273
Ensembl chr 3:124,730,433...124,749,273 		JBrowse link
G UNC13B unc-13 homolog B affects expression ISO Fluorouracil affects the expression of UNC13B mRNA CTD PMID:20421339 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338 		JBrowse link
G UNC5B unc-5 netrin receptor B affects expression EXP Fluorouracil affects the expression of UNC5B mRNA CTD PMID:16584549 NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864 		JBrowse link
G UNG uracil DNA glycosylase affects expression
affects response to substance		 EXP Fluorouracil affects the expression of UNG protein
UNG protein affects the susceptibility to Fluorouracil		 CTD PMID:16951200 PMID:18714155 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725 		JBrowse link
G UPP1 uridine phosphorylase 1 increases expression
affects response to substance
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of UPP1 mRNA; Fluorouracil results in increased expression of UPP1 protein
UPP1 protein affects the susceptibility to Fluorouracil
[UPP1 protein results in increased metabolism of Uridine] which affects the susceptibility to Fluorouracil
UPP1 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 PMID:15331170 PMID:15772079 PMID:24737281 NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736 		JBrowse link
G UPRT uracil phosphoribosyltransferase homolog increases metabolic processing EXP UPRT protein results in increased metabolism of Fluorouracil CTD PMID:18575323 NCBI chr  X:75,156,369...75,304,897
Ensembl chr  X:75,156,388...75,304,885 		JBrowse link
G UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X affects expression EXP Fluorouracil affects the expression of UQCR10 mRNA CTD PMID:34151400 NCBI chr22:29,767,369...29,770,413
Ensembl chr22:29,767,369...29,770,413 		JBrowse link
G UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI increases expression EXP Fluorouracil results in increased expression of UQCR11 mRNA CTD PMID:34151400 NCBI chr19:1,597,169...1,605,462
Ensembl chr19:1,597,169...1,605,473 		JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of UQCRB mRNA] CTD PMID:15016801 NCBI chr 8:96,222,947...96,235,545
Ensembl chr 8:96,222,947...96,235,546 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 decreases expression EXP Fluorouracil results in decreased expression of UQCRC2 mRNA CTD PMID:34151400 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660 		JBrowse link
G UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 affects expression EXP Fluorouracil affects the expression of UQCRFS1 mRNA CTD PMID:34151400 NCBI chr19:29,205,320...29,213,151
Ensembl chr19:29,205,320...29,213,151 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein affects expression EXP Fluorouracil affects the expression of UQCRH mRNA CTD PMID:34151400 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
G UROD uroporphyrinogen decarboxylase decreases response to substance EXP UROD protein results in decreased susceptibility to Fluorouracil CTD PMID:21270338 NCBI chr 1:45,012,254...45,015,575
Ensembl chr 1:45,010,950...45,015,575 		JBrowse link
G USH2A usherin multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of USH2A mRNA] CTD PMID:15016801 NCBI chr 1:215,622,891...216,423,448
Ensembl chr 1:215,622,891...216,423,448 		JBrowse link
G USP14 ubiquitin specific peptidase 14 decreases expression EXP Fluorouracil results in decreased expression of USP14 protein CTD PMID:16803524 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked affects response to substance EXP USP9X protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:41,085,445...41,236,579
Ensembl chr  X:41,085,445...41,236,579 		JBrowse link
G UTP3 UTP3 small subunit processome component multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of UTP3 mRNA CTD PMID:16391804 NCBI chr 4:70,688,532...70,690,551
Ensembl chr 4:70,688,532...70,690,551 		JBrowse link
G UXT ubiquitously expressed prefoldin like chaperone increases expression EXP Fluorouracil results in increased expression of UXT protein CTD PMID:15585135 PMID:16803524 NCBI chr  X:47,651,796...47,659,180
Ensembl chr  X:47,651,796...47,659,180 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of VANGL2 mRNA] CTD PMID:15016801 NCBI chr 1:160,400,564...160,428,670
Ensembl chr 1:160,400,564...160,428,678 		JBrowse link
G VASP vasodilator stimulated phosphoprotein multiple interactions
decreases expression		 ISO Fluorouracil promotes the reaction [resveratrol results in decreased expression of VASP protein]; resveratrol promotes the reaction [Fluorouracil results in decreased expression of VASP protein] CTD PMID:25936796 NCBI chr19:45,507,479...45,526,983
Ensembl chr19:45,506,579...45,526,989 		JBrowse link
G VAT1 vesicle amine transport 1 increases expression EXP Fluorouracil results in increased expression of VAT1 mRNA CTD PMID:16101138 NCBI chr17:43,014,607...43,022,385
Ensembl chr17:43,014,607...43,025,123 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 decreases expression EXP Fluorouracil results in decreased expression of VAV3 mRNA CTD PMID:16557594 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
G VCL vinculin affects response to substance EXP VCL protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:73,998,116...74,121,363
Ensembl chr10:73,995,193...74,121,363 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression
multiple interactions
increases expression
decreases response to substance		 EXP
ISO		 Fluorouracil results in decreased expression of VEGFA mRNA; Fluorouracil results in decreased expression of VEGFA protein
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of VEGFA protein]
Fluorouracil promotes the reaction [Resveratrol results in decreased expression of VEGFA protein]; Fluorouracil promotes the reaction [Valsartan results in decreased expression of VEGFA mRNA]; Resveratrol promotes the reaction [Fluorouracil results in decreased expression of VEGFA protein]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of VEGFA mRNA]
Fluorouracil results in increased expression of VEGFA protein
VEGFA mRNA results in decreased susceptibility to Fluorouracil; VEGFA protein results in decreased susceptibility to Fluorouracil
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of VEGFA mRNA]; VEGFA protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]
Fluorouracil results in increased expression of VEGFA mRNA		 CTD PMID:15817675 PMID:17039268 PMID:17786339 PMID:17982676 PMID:18494554 More... NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VGF VGF nerve growth factor inducible increases expression EXP Fluorouracil results in increased expression of VGF mRNA CTD PMID:24737281 NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569 		JBrowse link
G VIM vimentin increases expression
multiple interactions		 EXP Fluorouracil results in increased expression of VIM protein
resveratrol inhibits the reaction [Fluorouracil results in increased expression of VIM protein]		 CTD PMID:26310874 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VPREB3 V-set pre-B cell surrogate light chain 3 affects expression EXP Fluorouracil affects the expression of VPREB3 mRNA CTD PMID:16584549 NCBI chr22:23,752,743...23,754,425
Ensembl chr22:23,752,743...23,754,425 		JBrowse link
G VPS35 VPS35 retromer complex component affects expression EXP Fluorouracil affects the expression of VPS35 mRNA CTD PMID:16584549 NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518 		JBrowse link
G VPS37A VPS37A subunit of ESCRT-I increases response to substance EXP VPS37A protein results in increased susceptibility to Fluorouracil CTD PMID:31152734 NCBI chr 8:17,246,958...17,333,455
Ensembl chr 8:17,246,931...17,302,427 		JBrowse link
G VPS52 VPS52 subunit of GARP complex decreases expression EXP Fluorouracil results in decreased expression of VPS52 mRNA CTD PMID:16709241 NCBI chr 6:33,250,272...33,271,965
Ensembl chr 6:33,250,272...33,272,047 		JBrowse link
G WARS1 tryptophanyl-tRNA synthetase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of WARS1 mRNA] CTD PMID:15016801 NCBI chr14:100,333,790...100,376,327
Ensembl chr14:100,333,790...100,376,805 		JBrowse link
G WBP4 WW domain binding protein 4 affects expression EXP Fluorouracil affects the expression of WBP4 mRNA CTD PMID:16584549 NCBI chr13:41,061,509...41,084,006
Ensembl chr13:41,061,509...41,084,006 		JBrowse link
G WDR4 WD repeat domain 4 decreases expression EXP Fluorouracil results in decreased expression of WDR4 mRNA CTD PMID:16510598 NCBI chr21:42,843,094...42,892,998
Ensembl chr21:42,843,094...42,879,568 		JBrowse link
G WEE1 WEE1 G2 checkpoint kinase multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of WEE1 mRNA] CTD PMID:15016801 NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457 		JBrowse link
G WNT3 Wnt family member 3 increases expression ISO Fluorouracil results in increased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154 		JBrowse link
G WNT5A Wnt family member 5A increases expression
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of WNT5A mRNA
5-fluorouracil inhibits the reaction [N-methyl-N-nitrosourea increases expression of Wnt5a mRNA in colon]		 CTD
RGD		 PMID:31711903 PMID:28032729 RGD:150530464 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G WNT8A Wnt family member 8A decreases expression EXP Fluorouracil results in decreased expression of WNT8A mRNA CTD PMID:24737281 NCBI chr 5:138,077,367...138,092,365
Ensembl chr 5:138,083,990...138,092,365 		JBrowse link
G WT1 WT1 transcription factor decreases expression ISO Fluorouracil results in decreased expression of WT1 protein CTD PMID:21296659 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
G WTAP WT1 associated protein multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of WTAP mRNA] CTD PMID:15016801 NCBI chr 6:159,726,693...159,756,319
Ensembl chr 6:159,725,585...159,756,319 		JBrowse link
G XAF1 XIAP associated factor 1 increases response to substance
multiple interactions
increases expression		 ISO
EXP		 XAF1 protein results in increased susceptibility to Fluorouracil
EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; IL6 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; IL6 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; TGFB1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]
Fluorouracil results in increased expression of XAF1 mRNA; Fluorouracil results in increased expression of XAF1 protein		 CTD PMID:15843754 PMID:17570219 PMID:18544999 PMID:28507149 NCBI chr17:6,755,447...6,775,647
Ensembl chr17:6,755,447...6,775,647 		JBrowse link
G XAGE1B X antigen family member 1B affects response to substance EXP XAGE1B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:52,512,077...52,517,068
Ensembl chr  X:52,512,077...52,520,803 		JBrowse link
G XBP1 X-box binding protein 1 increases expression EXP Fluorouracil results in increased expression of XBP1 mRNA CTD PMID:15205334 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
G XIAP X-linked inhibitor of apoptosis increases expression
decreases expression
multiple interactions
affects response to substance		 EXP Fluorouracil results in increased expression of XIAP mRNA; Fluorouracil results in increased expression of XIAP protein
Fluorouracil results in decreased expression of XIAP mRNA
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of XIAP mRNA; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of XIAP mRNA; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of XIAP protein]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of XIAP mRNA]; XIAP protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]
XIAP affects the susceptibility to Fluorouracil		 CTD PMID:16628085 PMID:20876774 PMID:22963400 PMID:28599477 PMID:32800223 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G XIST X inactive specific transcript affects expression ISO Fluorouracil affects the expression of XIST protein CTD PMID:21296659 NCBI chr  X:73,820,656...73,852,714
Ensembl chr  X:73,820,649...73,852,723 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 multiple interactions EXP XRCC1 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; XRCC1 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] CTD PMID:22452940 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 multiple interactions EXP XRCC3 gene polymorphism affects the susceptibility to [Cisplatin co-treated with Fluorouracil] CTD PMID:21347786 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 multiple interactions EXP XRCC5 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] CTD PMID:18546291 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 multiple interactions EXP XRCC6 mRNA results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]; XRCC6 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin] CTD PMID:18546291 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048 		JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of YARS1 mRNA] CTD PMID:15016801 NCBI chr 1:32,775,239...32,817,358
Ensembl chr 1:32,775,237...32,818,031 		JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 increases expression EXP Fluorouracil results in increased expression of YARS2 mRNA CTD PMID:33770205 NCBI chr12:32,746,544...32,755,897
Ensembl chr12:32,727,490...32,755,897 		JBrowse link
G YBX1 Y-box binding protein 1 multiple interactions EXP Fluorouracil promotes the reaction [YBX1 protein binds to MVP promoter] CTD PMID:15750632 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805 		JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase affects response to substance EXP YES1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546 		JBrowse link
G YIF1A Yip1 interacting factor homolog A, membrane trafficking protein affects response to substance EXP YIF1A protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:66,284,580...66,289,143
Ensembl chr11:66,284,572...66,289,184 		JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta increases expression ISO Fluorouracil results in increased expression of YWHAB mRNA CTD PMID:19272435 NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon decreases expression EXP Fluorouracil results in decreased expression of YWHAE mRNA CTD PMID:16709241 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta decreases response to substance EXP YWHAH protein results in decreased susceptibility to Fluorouracil CTD PMID:30572915 NCBI chr22:31,944,535...31,957,603
Ensembl chr22:31,944,522...31,957,603 		JBrowse link
G ZBTB18 zinc finger and BTB domain containing 18 increases expression EXP Fluorouracil results in increased expression of ZBTB18 mRNA CTD PMID:16510598 NCBI chr 1:244,048,491...244,057,476
Ensembl chr 1:244,048,547...244,057,476 		JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 decreases expression EXP Fluorouracil results in decreased expression of ZBTB20 mRNA CTD PMID:16510598 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,292 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A affects response to substance
decreases expression		 EXP ZBTB7A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ZBTB7A protein		 CTD PMID:15352031 NCBI chr19:4,043,303...4,066,899
Ensembl chr19:4,043,303...4,066,899 		JBrowse link
G ZC3H3 zinc finger CCCH-type containing 3 affects expression EXP Fluorouracil affects the expression of ZC3H3 mRNA CTD PMID:16584549 NCBI chr 8:143,437,659...143,541,447
Ensembl chr 8:143,437,659...143,541,447 		JBrowse link
G ZCCHC18 zinc finger CCHC-type containing 18 affects expression ISO Fluorouracil affects the expression of ZCCHC18 mRNA CTD PMID:20421339 NCBI chr  X:104,112,523...104,115,842
Ensembl chr  X:104,112,131...104,115,842 		JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 increases expression EXP Fluorouracil results in increased expression of ZDHHC9 mRNA CTD PMID:17039268 NCBI chr  X:129,803,288...129,843,886
Ensembl chr  X:129,803,288...129,843,909 		JBrowse link
G ZFP42 ZFP42 zinc finger protein decreases expression ISO Fluorouracil results in decreased expression of ZFP42 protein CTD PMID:21296659 NCBI chr 4:187,995,771...188,005,246
Ensembl chr 4:187,995,771...188,005,046 		JBrowse link
G ZIM2 zinc finger imprinted 2 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZIM2 mRNA] CTD PMID:15016801 NCBI chr19:56,774,547...56,840,726
Ensembl chr19:56,774,547...56,840,731 		JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 decreases response to substance EXP ZKSCAN3 protein results in decreased susceptibility to Fluorouracil CTD PMID:18519692 NCBI chr 6:28,349,878...28,369,172
Ensembl chr 6:28,349,947...28,369,172 		JBrowse link
G ZMAT3 zinc finger matrin-type 3 multiple interactions
increases expression		 EXP TP53 protein promotes the reaction [Fluorouracil results in increased expression of ZMAT3 mRNA] CTD PMID:17982676 NCBI chr 3:179,017,223...179,072,513
Ensembl chr 3:178,960,121...179,072,215 		JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZMYND8 mRNA] CTD PMID:15016801 NCBI chr20:47,209,214...47,356,699
Ensembl chr20:47,209,214...47,356,889 		JBrowse link
G ZNF263 zinc finger protein 263 affects expression EXP Fluorouracil affects the expression of ZNF263 mRNA CTD PMID:34151400 NCBI chr16:3,283,491...3,301,401
Ensembl chr16:3,283,283...3,301,401 		JBrowse link
G ZNF266 zinc finger protein 266 multiple interactions EXP TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZNF266 mRNA] CTD PMID:15016801 NCBI chr19:9,412,429...9,435,573
Ensembl chr19:9,412,429...9,435,573 		JBrowse link
G ZNF282 zinc finger protein 282 increases expression EXP Fluorouracil results in increased expression of ZNF282 mRNA CTD PMID:33770205 NCBI chr 7:149,195,546...149,226,243
Ensembl chr 7:149,195,546...149,226,243 		JBrowse link
G ZNF32 zinc finger protein 32 multiple interactions EXP ZNF32 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr10:43,643,862...43,648,881
Ensembl chr10:43,643,860...43,648,881 		JBrowse link
G ZNF367 zinc finger protein 367 decreases expression EXP Fluorouracil results in decreased expression of ZNF367 mRNA CTD PMID:16510598 NCBI chr 9:96,385,941...96,418,370
Ensembl chr 9:96,385,941...96,418,370 		JBrowse link
G ZNF408 zinc finger protein 408 multiple interactions EXP [Fluorouracil co-treated with irinotecan] results in increased expression of ZNF408 mRNA CTD PMID:16391804 NCBI chr11:46,701,031...46,705,912
Ensembl chr11:46,701,030...46,705,912 		JBrowse link
G ZNF473 zinc finger protein 473 affects response to substance
increases expression		 EXP ZNF473 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of ZNF473 mRNA		 CTD PMID:15331170 NCBI chr19:50,026,005...50,048,776
Ensembl chr19:50,025,714...50,053,414 		JBrowse link
G ZNF518A zinc finger protein 518A affects expression ISO Fluorouracil affects the expression of ZFP518A mRNA CTD PMID:20421339 NCBI chr10:96,129,715...96,205,291
Ensembl chr10:96,129,715...96,205,288 		JBrowse link
G ZNF532 zinc finger protein 532 affects response to substance EXP ZNF532 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr18:58,862,924...58,986,480
Ensembl chr18:58,862,600...58,986,480 		JBrowse link
G ZNF552 zinc finger protein 552 multiple interactions EXP ZNF552 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:57,807,082...57,814,913
Ensembl chr19:57,803,841...57,814,913 		JBrowse link
G ZNF582 zinc finger protein 582 multiple interactions EXP ZNF582 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr19:56,382,751...56,393,534
Ensembl chr19:56,375,846...56,393,538 		JBrowse link
G ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 multiple interactions EXP ZRSR2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr  X:15,790,484...15,823,260
Ensembl chr  X:15,790,156...15,830,694 		JBrowse link
G ZSCAN18 zinc finger and SCAN domain containing 18 affects response to substance EXP ZSCAN18 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:58,083,842...58,118,426
Ensembl chr19:58,083,838...58,118,427 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26568
    role 26394
      biological role 26373
        xenobiotic 20421
          5-fluorouracil 1534
Path 2
Term Annotations click to browse term
  CHEBI ontology 26568
    subatomic particle 26544
      composite particle 26544
        hadron 26544
          baryon 26544
            nucleon 26544
              atomic nucleus 26544
                atom 26544
                  main group element atom 26293
                    p-block element atom 26293
                      carbon group element atom 25745
                        carbon atom 25707
                          organic molecular entity 25707
                            organic molecule 25453
                              organic cyclic compound 24499
                                organic heterocyclic compound 22430
                                  organic heteromonocyclic compound 19261
                                    diazines 13385
                                      pyrimidines 13232
                                        pyrimidine nucleobase 8537
                                          uracil 7957
                                            5-fluorouracil 1534
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