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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-fluorouracil
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Accession:CHEBI:46345 term browser browse the term
Definition:A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Synonyms:exact_synonym: 5-fluoropyrimidine-2,4(1H,3H)-dione
 related_synonym: 5-FU;   5-Fluoracil;   5-Fluoropyrimidine-2,4-dione;   Formula=C4H3FN2O2;   InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9);   InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N;   SMILES=Fc1c[nH]c(=O)[nH]c1=O;   fluorouracil;   fluorouracilo;   fluorouracilum
 alt_id: CHEBI:2054;   CHEBI:46343
 xref: Beilstein:127172;   CAS:51-21-8;   DrugBank:DB00544;   Drug_Central:26;   HMDB:HMDB0014684;   KEGG:C07649;   KEGG:D00584;   LINCS:LSM-4261
 xref_mesh: MESH:D005472
 xref: PDBeChem:URF;   PMID:11356943;   PMID:12520460;   PMID:14769231;   PMID:19023200;   Reaxys:127172;   Wikipedia:Fluorouracil


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5-fluorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS1 mRNA] CTD PMID:15016801 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
increases expression		 ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Fluorouracil; ABCB1 gene SNP affects the susceptibility to [Cisplatin co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
Fluorouracil results in decreased expression of ABCB1 mRNA
Fluorouracil results in increased expression of ABCB1 protein		 CTD PMID:12576456 PMID:15239124 PMID:17287894 PMID:21332314 PMID:21833476 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression
decreases response to substance		 ISO Fluorouracil results in decreased expression of ABCB6 mRNA
ABCB6 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:20737486 PMID:25202056 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:32800223 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects response to substance
multiple interactions		 ISO ABCC2 protein affects the susceptibility to Fluorouracil
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA		 CTD PMID:16217747 PMID:32800223 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases response to substance
multiple interactions		 ISO ABCC5 protein results in decreased susceptibility to Fluorouracil
5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Fluorouracil]; ABCC5 protein results in increased export of and results in decreased susceptibility to Fluorouracil		 CTD PMID:15897250 PMID:19077464 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects response to substance
increases expression		 ISO ABCC6 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of ABCC6 protein		 CTD PMID:15352031 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 PMID:21712253 PMID:21833476 PMID:32800223 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abhd12b abhydrolase domain containing 12B decreases expression ISO Fluorouracil results in decreased expression of ABHD12B mRNA CTD PMID:24737281 NCBI chr 6:88,668,627...88,696,435
Ensembl chr 6:88,668,642...88,696,458 		JBrowse link
G Abi1 abl-interactor 1 increases expression ISO Fluorouracil results in increased expression of ABI1 mRNA CTD PMID:19272435 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Abi2 abl-interactor 2 decreases expression ISO Fluorouracil results in decreased expression of ABI2 mRNA CTD PMID:19272435 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression ISO Fluorouracil results in decreased expression of ACAD9 mRNA CTD PMID:34151400 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression ISO Fluorouracil results in increased expression of ACADL protein CTD PMID:15585135 PMID:16803524 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Ackr3 atypical chemokine receptor 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA] CTD PMID:15016801 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects response to substance ISO ACOT13 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 affects response to substance ISO ACOT7 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA] CTD PMID:15016801 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Actb actin, beta decreases expression ISO Fluorouracil results in decreased expression of ACTB protein CTD PMID:21296659 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Fluorouracil results in decreased expression of ACTC1 protein CTD PMID:21296659 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Fluorouracil results in decreased expression of ACTG2 mRNA CTD PMID:16709241 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Acy1 aminoacylase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA] CTD PMID:15016801 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682 		JBrowse link
G Adam10 ADAM metallopeptidase domain 10 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA] CTD PMID:15016801 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam3a ADAM metallopeptidase domain 3A multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA] CTD PMID:15016801 NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA] CTD PMID:15016801 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO Fluorouracil results in decreased expression of ADCY9 mRNA CTD PMID:19219653 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Add3 adducin 3 affects response to substance ISO ADD3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 affects response to substance ISO ADGRG1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 affects response to substance ISO ADGRG6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123 		JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 affects response to substance ISO ADGRL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141 		JBrowse link
G Adm adrenomedullin affects response to substance ISO ADM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adss2 adenylosuccinate synthase 2 decreases expression
increases expression		 ISO Fluorouracil results in decreased expression of ADSS2 mRNA
Fluorouracil results in increased expression of ADSS2 protein		 CTD PMID:15585135 PMID:16709241 PMID:16803524 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604 		JBrowse link
G Afp alpha-fetoprotein increases expression
decreases expression		 ISO Fluorouracil results in increased expression of AFP protein
Fluorouracil results in decreased expression of AFP; Fluorouracil results in decreased expression of AFP mRNA		 CTD PMID:20448262 PMID:21296659 PMID:26272751 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 decreases expression ISO Fluorouracil results in decreased expression of AGAP3 mRNA CTD PMID:16709241 NCBI chr 4:10,674,746...10,724,848
Ensembl chr 4:10,674,064...10,725,244 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA] CTD PMID:15016801 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of AHNAK protein
AHNAK protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
increases expression		 ISO [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased expression of AIFM1 protein
[Fluorouracil co-treated with casticin] results in increased expression of AIFM1 protein
Fluorouracil results in increased expression of AIFM1 protein		 CTD PMID:16168113 PMID:32270916 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akap12 A-kinase anchoring protein 12 affects expression ISO Fluorouracil affects the expression of AKAP12 mRNA CTD PMID:16584549 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 affects expression ISO Fluorouracil affects the expression of AKR1B10 mRNA CTD PMID:16584549 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 affects expression
affects response to substance		 ISO Fluorouracil affects the expression of AKR1C1 mRNA
AKR1C1 protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16584549 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects response to substance ISO AKR1C2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects expression
affects response to substance		 ISO Fluorouracil affects the expression of AKR1C3 mRNA
AKR1C3 protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16584549 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
affects phosphorylation
decreases phosphorylation
affects expression		 ISO [Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein; AG 1879 inhibits the reaction [Fluorouracil results in increased phosphorylation of AKT1 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Nicotine affects the reaction [Fluorouracil affects the phosphorylation of AKT1 protein]
Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]
Fluorouracil results in decreased phosphorylation of AKT1 protein
Fluorouracil affects the expression of AKT1 mRNA		 CTD PMID:16724238 PMID:17918158 PMID:18794807 PMID:19885610 PMID:24095863 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO Fluorouracil results in increased expression of AKT2 protein CTD PMID:16803524 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alb albumin multiple interactions ISO [Leucovorin co-treated with Cisplatin co-treated with Fluorouracil] results in decreased expression of ALB protein CTD PMID:20180123 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule affects response to substance
decreases expression		 ISO ALCAM protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALCAM protein		 CTD PMID:15352031 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects response to substance ISO ALDH1A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects response to substance
decreases expression		 ISO ALDH1A3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ALDH1A3 protein		 CTD PMID:15352031 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 affects response to substance ISO ALDH3A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA] CTD PMID:15016801 NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912 		JBrowse link
G Alkbh8 alkB homolog 8, tRNA methyltransferase decreases expression ISO Fluorouracil results in decreased expression of ALKBH8 mRNA CTD PMID:16510598 NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165 		JBrowse link
G Amfr autocrine motility factor receptor multiple interactions ISO AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 decreases expression ISO Fluorouracil results in decreased expression of AMPD2 mRNA CTD PMID:19219653 NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271 		JBrowse link
G Amt aminomethyltransferase increases expression ISO Fluorouracil results in increased expression of AMT protein CTD PMID:15585135 PMID:16803524 NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126 		JBrowse link
G Ang angiogenin affects response to substance ISO ANG protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angpt1 angiopoietin 1 multiple interactions
increases expression		 ISO ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein]
Fluorouracil results in increased expression of ANGPT1 protein		 CTD PMID:17786339 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Angpt2 angiopoietin 2 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of ANGPT2 protein
ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]		 CTD PMID:17786339 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl2 angiopoietin-like 2 multiple interactions ISO ANGPTL2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Fluorouracil results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Angptl4 angiopoietin-like 4 affects response to substance ISO ANGPTL4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Fluorouracil results in increased expression of ANKRD1 mRNA CTD PMID:17039268 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 increases expression
affects expression		 ISO Fluorouracil results in increased expression of ANKRD11 mRNA
Fluorouracil affects the expression of ANKRD11 mRNA		 CTD PMID:16510598 PMID:16584549 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962 		JBrowse link
G Anln anillin, actin binding protein decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of ANLN mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA]		 CTD PMID:15016801 PMID:17982676 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA] CTD PMID:15016801 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Anxa1 annexin A1 affects response to substance
decreases expression		 ISO ANXA1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of ANXA1 protein		 CTD PMID:15352031 PMID:16217747 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa2 annexin A2 decreases response to substance
increases expression
multiple interactions		 ISO ANXA2 mRNA results in decreased susceptibility to Fluorouracil
Fluorouracil results in increased expression of ANXA2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA]		 CTD PMID:15152939 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa3 annexin A3 increases expression ISO Fluorouracil results in increased expression of ANXA3 mRNA CTD PMID:17039268 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa4 annexin A4 decreases expression ISO Fluorouracil results in decreased expression of ANXA4 mRNA CTD PMID:15109396 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of AP2S1 mRNA CTD PMID:16391804 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905 		JBrowse link
G Ap3s1 adaptor related protein complex 3 subunit sigma 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA] CTD PMID:15016801 NCBI chr18:39,462,728...39,531,622
Ensembl chr18:39,462,765...39,531,622 		JBrowse link
G Ap4s1 adaptor related protein complex 4 subunit sigma 1 decreases expression ISO Fluorouracil results in decreased expression of AP4S1 mRNA CTD PMID:16510598 NCBI chr 6:69,133,403...69,174,488
Ensembl chr 6:69,133,373...69,175,496 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression
affects expression		 ISO Fluorouracil results in increased expression of APAF1 mRNA
Fluorouracil affects the expression of APAF1 mRNA		 CTD PMID:16557594 PMID:34151400 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apba2 amyloid beta precursor protein binding family A member 2 affects response to substance ISO APBA2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:118,053,270...118,286,858
Ensembl chr 1:118,103,219...118,285,699 		JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 affects response to substance ISO APBB2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Fluorouracil CTD PMID:19470598 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apob apolipoprotein B multiple interactions
decreases expression
decreases secretion		 ISO ursodoxicoltaurine inhibits the reaction [Fluorouracil results in decreased expression of APOB mRNA]
Fluorouracil results in decreased secretion of APOB protein		 CTD PMID:32535746 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc1 apolipoprotein C1 affects response to substance ISO APOC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression
decreases secretion		 ISO Fluorouracil results in decreased expression of APOC3 mRNA
Fluorouracil results in decreased secretion of APOC3 protein		 CTD PMID:32535746 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Aqp6 aquaporin 6 decreases expression ISO Fluorouracil results in decreased expression of AQP6 mRNA CTD PMID:34151400 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194 		JBrowse link
G Aqp9 aquaporin 9 increases uptake EXP AQP9 protein results in increased uptake of Fluorouracil CTD PMID:9733774 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Areg amphiregulin affects response to substance
increases expression		 ISO AREG affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of AREG mRNA		 CTD PMID:15067352 PMID:16709241 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arf1 ARF GTPase 1 multiple interactions ISO ARF1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arf3 ARF GTPase 3 affects response to substance ISO ARF3 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002 		JBrowse link
G Arfgap1 ARF GTPase activating protein 1 increases expression ISO Fluorouracil results in increased expression of ARFGAP1 protein CTD PMID:15331170 NCBI chr 3:168,084,560...168,099,948
Ensembl chr 3:168,084,614...168,099,933 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta affects expression ISO Fluorouracil affects the expression of ARHGDIB mRNA CTD PMID:34151400 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Arid5b AT-rich interaction domain 5B affects response to substance ISO ARID5B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433 		JBrowse link
G Arl4c ARF like GTPase 4C increases expression ISO Fluorouracil results in increased expression of ARL4C mRNA CTD PMID:16510598 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513 		JBrowse link
G Arl6ip5 ARF like GTPase 6 interacting protein 5 multiple interactions ISO ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Cisplatin]; ARL6IP5 protein affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] CTD PMID:22452940 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA] CTD PMID:15016801 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299 		JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 decreases expression ISO Fluorouracil results in decreased expression of ARPC3 mRNA CTD PMID:16709241 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance
multiple interactions		 ISO ASAH1 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of ASS1 mRNA CTD PMID:16391804 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atf3 activating transcription factor 3 affects expression
increases expression
multiple interactions		 ISO Fluorouracil affects the expression of ATF3 mRNA
Fluorouracil results in increased expression of ATF3 mRNA; Fluorouracil results in increased expression of ATF3 protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA]		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:16709241 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Fluorouracil results in increased expression of ATF4 protein CTD PMID:29879413 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 affects expression ISO Fluorouracil affects the expression of ATF6 mRNA CTD PMID:34151400 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg12 autophagy related 12 decreases expression ISO Fluorouracil results in decreased expression of ATG12 mRNA CTD PMID:16510598 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atm ATM serine/threonine kinase decreases response to substance ISO ATM protein results in decreased susceptibility to Fluorouracil CTD PMID:35608750 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 affects expression ISO Fluorouracil affects the expression of ATOH8 mRNA CTD PMID:16584549 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions
affects expression		 ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA]
Fluorouracil affects the expression of ATP5F1D mRNA		 CTD PMID:15016801 PMID:34151400 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression ISO Fluorouracil affects the expression of ATP5PB mRNA CTD PMID:34151400 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 increases expression ISO Fluorouracil results in increased expression of ATP5PF mRNA CTD PMID:34151400 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO ATP5PO mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp7b ATPase copper transporting beta increases response to substance ISO ATP7B mRNA results in increased susceptibility to Fluorouracil CTD PMID:18593893 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of ATP9A protein
ATP9A protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818 		JBrowse link
G Atxn10 ataxin 10 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA] CTD PMID:15016801 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087 		JBrowse link
G Aurka aurora kinase A decreases expression ISO Fluorouracil results in decreased expression of AURKA mRNA CTD PMID:15205334 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aven apoptosis and caspase activation inhibitor decreases expression
increases expression		 ISO Fluorouracil results in decreased expression of AVEN mRNA
Fluorouracil results in increased expression of AVEN mRNA		 CTD PMID:16510598 PMID:16709241 NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634 		JBrowse link
G Axin1 axin 1 multiple interactions EXP 5-fluorouracil inhibits the reaction [N-methyl-N-nitrosourea decreases expression of Axin1 mRNA in colon] RGD PMID:28032729 RGD:150530464 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA] CTD PMID:31129132 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag3 BAG cochaperone 3 affects response to substance ISO BAG3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
increases response to substance
multiple interactions		 ISO Fluorouracil results in increased expression of BAK1; Fluorouracil results in increased expression of BAK1 mRNA; Fluorouracil results in increased expression of BAK1 protein
BAK1 mRNA results in increased susceptibility to Fluorouracil
mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BAK1 protein]		 CTD PMID:9792140 PMID:15489892 PMID:16557594 PMID:18593893 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Barx2 BARX homeobox 2 increases expression ISO Fluorouracil results in increased expression of BARX2 protein CTD PMID:15585135 PMID:16803524 NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases response to substance
decreases expression
increases expression
affects expression		 ISO
EXP		 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in increased expression of BAX mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of BAX protein; [SM-1 compound co-treated with Fluorouracil] results in increased expression of BAX protein; [wogonin co-treated with Fluorouracil] results in increased expression of BAX protein; Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BAX mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BAX mRNA]; Fluorouracil affects the reaction [rebamipide results in decreased expression of BAX protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of BAX protein]; Fluorouracil promotes the reaction [andrographolide affects the folding of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]; Fluorouracil promotes the reaction [Plant Extracts results in increased expression of BAX protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; SM-1 compound promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]
BAX protein results in increased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BAX protein
[Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in increased expression of BAX protein; casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]; IL1RN protein affects the reaction [Fluorouracil results in increased expression of BAX protein]
Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein
Fluorouracil results in increased expression of BAX; Fluorouracil results in increased expression of BAX mRNA; Fluorouracil results in increased expression of BAX protein
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]		 CTD PMID:9388485 PMID:9792140 PMID:11062132 PMID:11750847 PMID:12442003 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases response to substance
increases expression
multiple interactions		 ISO BBC3 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of BBC3 mRNA; Fluorouracil results in increased expression of BBC3 protein
[[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]		 CTD PMID:14665630 PMID:15016801 PMID:15489892 PMID:16481741 PMID:16557594 More... NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 multiple interactions ISO BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607 		JBrowse link
G Bbx BBX high mobility group box domain containing affects response to substance ISO BBX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of BCAR3 protein
BCAR3 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA] CTD PMID:15016801 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha affects expression ISO Fluorouracil affects the expression of BCKDHA mRNA CTD PMID:16584549 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases response to substance
decreases expression
increases expression
increases phosphorylation
affects response to substance
affects expression		 ISO
EXP		 [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein; [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 mRNA; [Fluorouracil co-treated with Irinotecan] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 mRNA; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BCL2 protein; [wogonin co-treated with Fluorouracil] results in decreased expression of BCL2 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA]; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of BCL2 protein]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of BCL2 mRNA]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]
BCL2 protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BCL-2 protein; Fluorouracil results in decreased expression of BCL2; Fluorouracil results in decreased expression of BCL2 mRNA; Fluorouracil results in decreased expression of BCL2 protein
Fluorouracil results in increased expression of BCL2 mRNA
Fluorouracil results in increased phosphorylation of BCL2 protein
[Fluorouracil co-treated with casticin] results in decreased expression of BCL2 protein; [Fluorouracil co-treated with Chitosan co-treated with polyaspartate] results in decreased expression of BCL2 protein; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]
Fluorouracil results in increased expression of BCL2 mRNA; Fluorouracil results in increased expression of BCL2 protein
BCL2 protein affects the susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]		 CTD PMID:7654318 PMID:9388485 PMID:14503796 PMID:15177426 PMID:15754201 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases response to substance
affects expression
decreases expression
increases expression
affects response to substance		 ISO
EXP		 3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 protein; BAY 11-7085 inhibits the reaction [[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2L1 mRNA]; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil affects the reaction [rebamipide results in increased expression of BCL2L1 protein]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; rebamipide inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
BCL2L1 protein results in decreased susceptibility to Fluorouracil
Fluorouracil affects the expression of BCL2L1 mRNA; Fluorouracil affects the expression of BCL2L1 protein
Fluorouracil results in decreased expression of BCL2L1; Fluorouracil results in decreased expression of BCL2L1 mRNA; Fluorouracil results in decreased expression of BCL2L1 protein
Fluorouracil results in increased expression of BCL2L1 mRNA; Fluorouracil results in increased expression of BCL2L1 protein
3-methyladenine inhibits the reaction [Fluorouracil results in increased expression of BCL2L1 protein]; casticin promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]; Fluorouracil promotes the reaction [casticin results in decreased expression of BCL2L1 protein]; IL1RN protein inhibits the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]
BCL2L1 protein affects the susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]		 CTD PMID:12442003 PMID:15289866 PMID:15767554 PMID:16407826 PMID:16557594 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression		 ISO Fluorouracil affects the reaction [rebamipide results in decreased expression of BCL2L11 protein]; rebamipide inhibits the reaction [Fluorouracil results in increased expression of BCL2L11 protein] CTD PMID:29054700 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l12 Bcl2 like 12 multiple interactions ISO [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of BCL2L12 mRNA CTD PMID:19015929 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Fluorouracil results in decreased expression of BDH1 protein CTD PMID:15585135 PMID:16803524 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA] CTD PMID:15016801 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP Fluorouracil results in decreased expression of BDNF protein CTD PMID:18702703 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bean1 brain expressed, associated with NEDD4, 1 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of BEAN1 protein
BEAN1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr19:739,551...786,395
Ensembl chr19:739,551...787,537 		JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression		 ISO BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fluorouracil results in increased expression of BECN1 protein
Apigenin promotes the reaction [Fluorouracil results in increased expression of BECN1 protein]; Fluorouracil promotes the reaction [Apigenin results in increased expression of BECN1 protein]		 CTD PMID:16896004 PMID:28025107 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP Fluorouracil results in increased expression of BGLAP mRNA CTD PMID:16888818 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 affects response to substance ISO BHLHE41 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases response to substance
decreases expression
decreases response to substance
increases expression		 ISO [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil results in increased cleavage of and results in increased activity of BID protein; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]
Fluorouracil results in decreased expression of BID protein
BID protein mutant form results in decreased susceptibility to Fluorouracil
casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein]		 CTD PMID:15095271 PMID:15289866 PMID:15754201 PMID:21474236 PMID:32270916 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Fluorouracil results in increased expression of BIRC2 mRNA CTD PMID:17039268 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
affects expression		 ISO Fluorouracil results in increased expression of BIRC3 mRNA
Fluorouracil affects the expression of BIRC3 mRNA		 CTD PMID:16557594 PMID:34151400 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance
affects response to substance
multiple interactions
decreases expression
increases expression		 ISO BIRC5 protein results in decreased susceptibility to Fluorouracil; BIRC5 results in decreased susceptibility to Fluorouracil
BIRC5 affects the susceptibility to Fluorouracil; BIRC5 protein affects the susceptibility to Fluorouracil
[Fluorouracil co-treated with RNF34 protein] results in increased expression of BIRC5 protein; [SM-1 compound co-treated with Fluorouracil] results in decreased expression of BIRC5 mRNA; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; Gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]; SM-1 compound inhibits the reaction [Fluorouracil results in increased expression of BIRC5 mRNA]; SM-1 compound promotes the reaction [Fluorouracil results in decreased expression of BIRC5 protein]
Fluorouracil results in decreased expression of BIRC5 mRNA; Fluorouracil results in decreased expression of BIRC5 protein
Fluorouracil results in increased expression of BIRC5 mRNA; Fluorouracil results in increased expression of BIRC5 protein		 CTD PMID:15067352 PMID:15109396 PMID:15685548 PMID:16217747 PMID:16546719 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 affects response to substance
decreases response to substance		 ISO BIRC6 protein affects the susceptibility to Fluorouracil
BIRC6 results in decreased susceptibility to Fluorouracil		 CTD PMID:18239605 PMID:21542283 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Fluorouracil CTD PMID:17437058 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Fluorouracil results in decreased expression of BLM mRNA CTD PMID:19272435 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Blvrb biliverdin reductase B affects response to substance ISO BLVRB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Fluorouracil results in increased expression of BNIP1 mRNA CTD PMID:33770205 NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157 		JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance		 ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA]
BNIP3 affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:15067352 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects response to substance
increases expression
decreases expression		 ISO BNIP3L affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of BNIP3L mRNA
Fluorouracil results in decreased expression of BNIP3L mRNA		 CTD PMID:15067352 PMID:15109396 PMID:16557594 PMID:16709241 PMID:17039268 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Boll boule homolog, RNA binding protein multiple interactions ISO BOLL mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA] CTD PMID:15016801 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931 		JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO Fluorouracil results in decreased expression of BORA mRNA CTD PMID:17374387 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
multiple interactions
decreases expression		 ISO Fluorouracil results in increased expression of BRCA1 mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA]		 CTD PMID:15607317 PMID:16101138 PMID:16557594 PMID:17982676 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brix1 biogenesis of ribosomes BRX1 decreases expression ISO Fluorouracil results in decreased expression of BRIX1 mRNA CTD PMID:16510598 NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:59,450,614...59,461,495 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of BTG2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA]		 CTD PMID:15016801 PMID:17982676 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Fluorouracil results in decreased expression of BUB1 mRNA CTD PMID:16709241 PMID:19272435 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Fluorouracil results in decreased expression of BUB1B mRNA CTD PMID:16557594 PMID:16709241 PMID:19272435 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein affects response to substance
decreases expression		 ISO BUB3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of BUB3 protein		 CTD PMID:15548681 PMID:15585135 PMID:16803524 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G C10h1orf35 similar to human chromosome 1 open reading frame 35 affects expression ISO Fluorouracil affects the expression of C1ORF35 mRNA CTD PMID:16584549 NCBI chr10:43,993,809...43,997,287
Ensembl chr10:43,993,668...43,997,289 		JBrowse link
G C1h11orf24 similar to human chromosome 11 open reading frame 24 affects response to substance ISO C11ORF24 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:200,945,188...200,953,953
Ensembl chr 1:200,945,180...200,962,585 		JBrowse link
G C4bpb complement component 4 binding protein, beta affects expression ISO Fluorouracil affects the expression of C4BPB mRNA CTD PMID:16584549 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
G C6h14orf132 similar to human chromosome 14 open reading frame 132 increases expression ISO Fluorouracil results in increased expression of C14ORF132 mRNA CTD PMID:16510598 NCBI chr 6:124,365,466...124,398,449 JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated affects response to substance ISO CABYR protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA] CTD PMID:15016801 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Calb2 calbindin 2 increases response to substance
increases expression		 ISO CALB2 protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of CALB2 mRNA		 CTD PMID:16510598 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Canx calnexin multiple interactions ISO CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA] CTD PMID:15016801 PMID:18678097 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects response to substance ISO CAP2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373 		JBrowse link
G Car12 carbonic anhydrase 12 multiple interactions ISO CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Car14 carbonic anhydrase 14 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA] CTD PMID:15016801 NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693 		JBrowse link
G Casd1 CAS1 domain containing 1 affects expression ISO Fluorouracil affects the expression of CASD1 mRNA CTD PMID:20421339 NCBI chr 4:32,659,196...32,739,228
Ensembl chr 4:32,658,748...32,739,202 		JBrowse link
G Casp1 caspase 1 increases cleavage ISO Fluorouracil results in increased cleavage of CASP1 protein CTD PMID:15162350 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp2 caspase 2 decreases expression ISO Fluorouracil results in decreased expression of CASP2 mRNA CTD PMID:34151400 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
decreases expression
increases cleavage
decreases cleavage
affects expression		 ISO
EXP		 Fluorouracil results in increased expression of CASP3; Fluorouracil results in increased expression of CASP3 mRNA; Fluorouracil results in increased expression of CASP3 protein; Fluorouracil results in increased expression of CASP3 protein modified form
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; casticin inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP3 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; IL1RN protein affects the reaction [Fluorouracil results in increased expression of CASP3 protein modified form]
Fluorouracil results in decreased expression of CASP3 mRNA
Fluorouracil results in increased cleavage of CASP3 protein
3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein]; [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP3 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP3; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP3 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP3 protein; [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein; [Fluorouracil co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased activity of CASP3 protein; [SM-1 compound co-treated with Fluorouracil] results in increased cleavage of CASP3 protein; [wogonin co-treated with Fluorouracil] results in increased activity of CASP3 protein; Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; Celecoxib inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]; chan-yu-bao-yuan-tang promotes the reaction [Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP3 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]; Fluorouracil promotes the reaction [chan-yu-bao-yuan-tang results in increased cleavage of and results in increased expression of CASP3 protein]; Fluorouracil promotes the reaction [gambogic acid results in decreased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CASP3 mRNA]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP3 protein]; Fluorouracil results in increased activity of and results in increased cleavage of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased activity of CASP3 protein; Fluorouracil results in increased cleavage of and results in increased expression of CASP3 protein; HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [Fluorouracil results in decreased cleavage of CASP3 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]; TNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in decreased cleavage of CASP3 protein]; Bosentan inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; Silybin inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]
Fluorouracil affects the expression of CASP3 mRNA		 CTD PMID:10891390 PMID:11300326 PMID:12414664 PMID:12934351 PMID:12941601 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of CASP4 protein
CASP4 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16217747 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 multiple interactions
affects expression		 ISO Fluorouracil results in increased cleavage of and results in increased activity of CASP6 protein; resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]; TP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]
Fluorouracil affects the expression of CASP6 mRNA		 CTD PMID:18497562 PMID:34151400 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
increases expression		 ISO [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein
Fluorouracil results in increased cleavage of CASP7 protein
Fluorouracil results in increased expression of CASP7 mRNA		 CTD PMID:16168113 PMID:26544897 PMID:34151400 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
increases expression
decreases expression
increases cleavage		 ISO [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CASP8 protein; [Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP8 protein; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP8; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP8 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP8 protein; [Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased cleavage of CASP8 protein]; Cadmium Chloride affects the reaction [Fluorouracil results in decreased expression of CASP8 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP3 protein]]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; CASP8 results in increased susceptibility to [andrographolide co-treated with Fluorouracil]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; Fluorouracil affects the reaction [Cadmium Chloride results in decreased expression of CASP8 mRNA]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP8 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP8 protein]; Fluorouracil promotes the reaction [TNFSF10 protein results in increased cleavage of and results in increased activity of CASP8 protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Fluorouracil results in increased activity of CASP8 protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]
Fluorouracil results in increased expression of CASP8 mRNA; Fluorouracil results in increased expression of CASP8 protein
Fluorouracil results in increased cleavage of CASP8 protein		 CTD PMID:10779637 PMID:10891390 PMID:12414664 PMID:14607657 PMID:15585135 More... NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
increases activity
decreases expression		 ISO
EXP		 [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of CASP9 mRNA; [Fluorouracil co-treated with aloe emodin] affects the expression of CASP9; [Fluorouracil co-treated with Cisplatin] results in increased activity of CASP9 protein; [Fluorouracil co-treated with Cisplatin] results in increased expression of CASP9 protein; Cadmium Chloride promotes the reaction [Fluorouracil results in decreased expression of CASP9 mRNA]; CASP8 affects the reaction [Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [aloe emodin results in increased expression of CASP9 protein modified form]; Fluorouracil promotes the reaction [andrographolide results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; PTGS2 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; RNF34 protein inhibits the reaction [Fluorouracil results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]
Fluorouracil results in increased cleavage of CASP9 protein
Fluorouracil results in increased expression of CASP9 protein
Apigenin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; casticin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; Fluorouracil promotes the reaction [Apigenin results in increased activity of CASP9 protein]
Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]		 CTD PMID:10779637 PMID:12414664 PMID:15546879 PMID:15996812 PMID:16168113 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression		 ISO
EXP		 Fluorouracil inhibits the reaction [casticin results in increased expression of CAT protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Luteolin results in decreased activity of CAT protein]; Fluorouracil promotes the reaction [Valsartan results in decreased activity of CAT protein]; Luteolin promotes the reaction [Fluorouracil results in decreased activity of CAT protein]; Valsartan promotes the reaction [Fluorouracil results in decreased activity of CAT protein]
[Fluorouracil co-treated with Arsenic Trioxide] results in decreased activity of CAT protein
Silybin inhibits the reaction [Fluorouracil results in decreased expression of CAT protein]		 CTD PMID:27836789 PMID:29117755 PMID:31288002 PMID:32270916 PMID:32752303 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 affects response to substance
decreases expression
increases expression		 ISO CAV1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CAV1 protein
Fluorouracil results in increased expression of CAV1 mRNA		 CTD PMID:15352031 PMID:24737281 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav2 caveolin 2 decreases expression
increases expression		 ISO Fluorouracil results in decreased expression of CAV2 mRNA
Fluorouracil results in increased expression of CAV2 mRNA		 CTD PMID:16510598 PMID:24737281 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Cbr3 carbonyl reductase 3 affects expression ISO Fluorouracil affects the expression of CBR3 mRNA CTD PMID:20421339 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA] CTD PMID:15016801 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Cbx1 chromobox 1 affects response to substance ISO CBX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096 		JBrowse link
G Ccdc186 coiled-coil domain containing 186 increases expression ISO Fluorouracil results in increased expression of CCDC186 mRNA CTD PMID:16510598 NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CCL2 mRNA
Fluorouracil promotes the reaction [Valsartan results in decreased expression of CCL2 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of CCL2 mRNA]		 CTD PMID:35235860 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn1 cellular communication network factor 1 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of CCN1 mRNA; Fluorouracil results in increased expression of CCN1 protein
CCN1 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:17699798 PMID:24737281 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 affects expression ISO Fluorouracil affects the expression of CCN2 mRNA CTD PMID:15205334 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Fluorouracil results in increased expression of CCN3 mRNA CTD PMID:16510598 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccna1 cyclin A1 multiple interactions
affects expression		 ISO [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCNA1 protein; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCNA1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCNA1 mRNA]
Fluorouracil affects the expression of CCNA1 mRNA; Fluorouracil affects the expression of CCNA1 protein		 CTD PMID:23941782 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
affects expression
affects response to substance		 ISO N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]
Fluorouracil results in decreased expression of CCNA2 mRNA; Fluorouracil results in decreased expression of CCNA2 protein
Fluorouracil affects the expression of CCNA2 mRNA
CCNA2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15205334 PMID:15546879 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression		 ISO N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]; TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]
Fluorouracil results in decreased expression of CCNB1 mRNA; Fluorouracil results in decreased expression of CCNB1 protein		 CTD PMID:15016801 PMID:15205334 PMID:15546879 PMID:16557594 PMID:17982676 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 multiple interactions
decreases expression		 ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA]
Fluorouracil results in decreased expression of CCNB2 mRNA; Fluorouracil results in decreased expression of CCNB2 protein		 CTD PMID:15016801 PMID:16557594 PMID:16709241 PMID:17982488 PMID:19272435 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnc cyclin C decreases expression ISO Fluorouracil results in decreased expression of CCNC mRNA CTD PMID:16709241 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584 		JBrowse link
G Ccnd1 cyclin D1 affects response to substance
multiple interactions
decreases expression
affects expression		 ISO CCND1 protein affects the susceptibility to Fluorouracil
[allose co-treated with Fluorouracil] results in decreased expression of CCND1 protein; [Cadmium Chloride co-treated with Fluorouracil] affects the expression of CCND1 protein; [Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA; Cadmium Chloride affects the reaction [Fluorouracil affects the expression of CCND1 mRNA]; Fluorouracil affects the reaction [Cadmium Chloride affects the expression of CCND1 mRNA]; Fluorouracil promotes the reaction [allose results in decreased expression of CCND1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein]
Fluorouracil results in decreased expression of CCND1 mRNA; Fluorouracil results in decreased expression of CCND1 protein
Fluorouracil affects the expression of CCND1 mRNA; Fluorouracil affects the expression of CCND1 protein
Fluorouracil promotes the reaction [Luteolin results in decreased expression of CCND1 protein]; Luteolin promotes the reaction [Fluorouracil results in decreased expression of CCND1 protein]		 CTD PMID:15352031 PMID:17982676 PMID:18930000 PMID:23941782 PMID:31288002 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 increases expression
affects response to substance
multiple interactions
decreases expression		 ISO Fluorouracil results in increased expression of CCND2 protein
CCND2 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA]		 CTD PMID:15016801 PMID:15352031 PMID:19272435 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnd3 cyclin D3 affects response to substance
increases expression		 ISO CCND3 affects the susceptibility to Fluorouracil; CCND3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCND3 mRNA		 CTD PMID:15067352 PMID:15548681 PMID:16709241 PMID:18383818 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression
increases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CCNE1 mRNA
Fluorouracil results in increased expression of CCNE1 mRNA; Fluorouracil results in increased expression of CCNE1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA; [Leucovorin co-treated with Fluorouracil] results in increased expression of CCNE1 mRNA		 CTD PMID:9930367 PMID:15342418 PMID:16101138 PMID:18930000 PMID:31587439 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 affects response to substance ISO CCNE2 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnf cyclin F affects response to substance ISO CCNF affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Ccng1 cyclin G1 affects response to substance
decreases expression
multiple interactions
increases expression		 ISO CCNG1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CCNG1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA]		 CTD PMID:15152939 PMID:16217747 PMID:16557594 PMID:16709241 PMID:17982676 More... NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccng2 cyclin G2 affects response to substance
increases expression
decreases expression		 ISO CCNG2 affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CCNG2 mRNA
Fluorouracil results in decreased expression of CCNG2 mRNA		 CTD PMID:15067352 PMID:16510598 PMID:16557594 PMID:17039268 PMID:18754885 More... NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccnjl cyclin J-like affects expression ISO Fluorouracil affects the expression of CCNJL mRNA CTD PMID:16584549 NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426 		JBrowse link
G Cd109 CD109 molecule affects response to substance ISO CD109 protein affects the susceptibility to Fluorouracil CTD PMID:37661780 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Cd24 CD24 molecule increases expression ISO Fluorouracil results in increased expression of CD24 mRNA CTD PMID:16510598 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Fluorouracil results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd34 CD34 molecule increases expression ISO Fluorouracil results in increased expression of CD34 protein CTD PMID:21296659 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd38 CD38 molecule affects expression ISO Fluorouracil affects the expression of CD38 mRNA CTD PMID:16584549 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd40 CD40 molecule decreases response to substance
multiple interactions		 ISO CD40 results in decreased susceptibility to Fluorouracil
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]		 CTD PMID:15611226 PMID:20188757 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule multiple interactions EXP [gimeracil co-treated with Fluorouracil] results in decreased expression of CD44 CTD PMID:12364819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd52 CD52 molecule affects expression
multiple interactions		 ISO Fluorouracil affects the expression of CD52 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA]		 CTD PMID:15016801 PMID:16584549 NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348 		JBrowse link
G Cd63 Cd63 molecule decreases expression ISO Fluorouracil results in decreased expression of CD63 CTD PMID:15485462 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
G Cd8a CD8 subunit alpha multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA] CTD PMID:15016801 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040 		JBrowse link
G Cd8b CD8 subunit beta affects response to substance
decreases expression		 ISO CD8B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CD8B protein		 CTD PMID:15352031 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553 		JBrowse link
G Cd9 CD9 molecule decreases expression ISO Fluorouracil results in decreased expression of CD9 protein CTD PMID:21296659 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cda cytidine deaminase multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil CTD PMID:10811482 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA] CTD PMID:15016801 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Fluorouracil results in decreased expression of CDC25A mRNA CTD PMID:16510598 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Fluorouracil results in decreased expression of CDC25B mRNA CTD PMID:16709241 PMID:19272435 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdc25c cell division cycle 25C affects response to substance
decreases expression		 ISO CDC25C protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDC25C mRNA		 CTD PMID:15548681 PMID:19272435 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme affects response to substance ISO CDC34 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186 		JBrowse link
G Cdc40 cell division cycle 40 increases expression ISO Fluorouracil results in increased expression of CDC40 protein CTD PMID:16803524 NCBI chr20:44,273,080...44,325,605
Ensembl chr20:44,273,089...44,325,358 		JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects response to substance ISO CDC42EP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200 		JBrowse link
G Cdc45 cell division cycle 45 multiple interactions
affects expression
decreases expression		 ISO [Leucovorin co-treated with Fluorouracil] results in increased expression of CDC45 mRNA
Fluorouracil affects the expression of CDC45 mRNA
Fluorouracil results in decreased expression of CDC45 mRNA		 CTD PMID:15342418 PMID:16557594 PMID:19272435 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc6 cell division cycle 6 affects expression
decreases expression
increases expression
multiple interactions		 ISO Fluorouracil affects the expression of CDC6 mRNA
Fluorouracil results in decreased expression of CDC6 mRNA
Fluorouracil results in increased expression of CDC6 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDC6 mRNA		 CTD PMID:15342418 PMID:16557594 PMID:16709241 PMID:17039268 PMID:19272435 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdc73 cell division cycle 73 decreases expression ISO Fluorouracil results in decreased expression of CDC73 mRNA CTD PMID:16510598 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Fluorouracil results in increased expression of CDCA5 mRNA CTD PMID:16709241 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca7 cell division cycle associated 7 affects expression ISO Fluorouracil affects the expression of CDCA7 mRNA CTD PMID:20421339 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353 		JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Fluorouracil results in decreased expression of CDCA8 mRNA CTD PMID:17374387 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 affects response to substance
multiple interactions
decreases expression		 ISO CDH1 protein affects the susceptibility to Fluorouracil
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CDH1 protein]		 CTD PMID:15352031 PMID:26310874 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh5 cadherin 5 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of CDH5 protein
Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]		 CTD PMID:21296659 PMID:31404653 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdh6 cadherin 6 decreases expression ISO Fluorouracil results in decreased expression of CDH6 mRNA CTD PMID:24737281 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228 		JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase affects expression ISO Fluorouracil affects the expression of CDIPT mRNA CTD PMID:16584549 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
affects expression
increases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CDK1 mRNA
Fluorouracil affects the expression of CDK1 mRNA
Fluorouracil results in increased expression of CDK1 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK1 mRNA		 CTD PMID:15152939 PMID:15205334 PMID:15342418 PMID:16557594 PMID:17039268 More... NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects response to substance
increases expression
multiple interactions		 ISO CDK2 protein affects the susceptibility to Fluorouracil; CDK2 protein modified form affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CDK2 mRNA
[Leucovorin co-treated with Fluorouracil] results in increased expression of CDK2 mRNA		 CTD PMID:15342418 PMID:15548681 PMID:16557594 PMID:18383818 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 affects expression ISO Fluorouracil affects the expression of CDK5R1 mRNA CTD PMID:15205334 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects response to substance
increases response to substance
decreases response to substance
multiple interactions
decreases expression
decreases degradation
increases expression		 ISO CDKN1A affects the susceptibility to Fluorouracil; CDKN1A protein affects the susceptibility to Fluorouracil
CDKN1A protein results in increased susceptibility to Fluorouracil
CDKN1A protein results in decreased susceptibility to Fluorouracil
[Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA; [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of CDKN1A protein; [Fluorouracil co-treated with Plant Extracts] results in increased expression of CDKN1A protein; [Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA; CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; CDKN1A protein affects the reaction [Fluorouracil results in decreased expression of UBE2C protein]; Fluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]; Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CDKN1A mRNA]; Fluorouracil promotes the reaction [temsirolimus results in increased expression of CDKN1A mRNA]; mithramycin A inhibits the reaction [Fluorouracil results in increased expression of CDKN1A protein]; Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Simvastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; temsirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]
Fluorouracil results in decreased expression of CDKN1A protein
Fluorouracil results in increased expression of CDKN1A; Fluorouracil results in increased expression of CDKN1A mRNA; Fluorouracil results in increased expression of CDKN1A protein
Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]		 CTD PMID:14646558 PMID:14665630 PMID:15016801 PMID:15067352 PMID:15205334 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects response to substance
decreases expression		 ISO CDKN1B protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CDKN1B mRNA		 CTD PMID:17217824 PMID:18930000 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C affects response to substance
increases expression		 ISO CDKN1C affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CDKN1C mRNA		 CTD PMID:15067352 PMID:19272435 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO Fluorouracil results in decreased expression of CDKN2A protein CTD PMID:17982676 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2aip CDKN2A interacting protein affects response to substance ISO CDKN2AIP protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Fluorouracil results in decreased expression of CDKN2C mRNA CTD PMID:16557594 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA] CTD PMID:15016801 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cdx2 caudal type homeo box 2 decreases expression ISO Fluorouracil results in decreased expression of CDX2 protein
Fluorouracil results in decreased expression of CDX2 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Fluorouracil results in increased expression of CEBPB mRNA CTD PMID:16557594 PMID:16584549 PMID:34151400 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cenpq centromere protein Q affects response to substance
increases expression		 ISO CENPQ protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CENPQ mRNA		 CTD PMID:15331170 NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789 		JBrowse link
G Cenpu centromere protein U affects response to substance ISO CENPU protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cenpx centromere protein X affects response to substance ISO CENPX protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:105,991,469...105,994,310 JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Fluorouracil results in decreased expression of CEP55 mRNA CTD PMID:17039268 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression
decreases expression		 ISO Fluorouracil results in increased expression of CER1 mRNA
Fluorouracil results in decreased expression of CER1 mRNA		 CTD PMID:24737281 PMID:26272751 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases expression		 ISO Fluorouracil promotes the reaction [TP53 protein binds to CES2 intron]; TP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA] CTD PMID:15205334 PMID:16963839 PMID:17287894 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression
decreases expression
affects response to substance		 ISO [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; [Fluorouracil results in decreased expression of CFLAR protein] which results in increased susceptibility to TNFSF10 protein; CFLAR protein alternative form inhibits the reaction [Fluorouracil results in increased activity of TNFSF10 protein]; CFLAR protein inhibits the reaction [Fluorouracil results in increased susceptibility to TNFSF10 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]
Fluorouracil results in increased expression of CFLAR mRNA
Fluorouracil results in decreased expression of CFLAR mRNA; Fluorouracil results in decreased expression of CFLAR protein
CFLAR protein affects the susceptibility to Fluorouracil		 CTD PMID:15152939 PMID:15548681 PMID:16217747 PMID:16373718 PMID:17045692 More... NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chek1 checkpoint kinase 1 affects response to substance
multiple interactions
increases expression
decreases expression		 ISO CHEK1 protein affects the susceptibility to Fluorouracil
[CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil; Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK1 protein; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]; TP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]		 CTD PMID:15016801 PMID:18698031 PMID:19272435 PMID:21613406 PMID:22194930 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK2 protein CTD PMID:21613406 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Fluorouracil results in increased expression of CHI3L1 mRNA CTD PMID:15205334 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA] CTD PMID:15016801 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chst7 carbohydrate sulfotransferase 7 affects response to substance ISO CHST7 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:2,396,260...2,432,828
Ensembl chr  X:2,393,874...2,432,840 		JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects response to substance ISO CIAO1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b increases expression ISO Fluorouracil results in increased expression of CIDEB protein CTD PMID:15585135 PMID:16803524 NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects response to substance ISO CITED2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ckb creatine kinase B affects response to substance ISO CKB protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Fluorouracil results in decreased expression of CKS2 mRNA CTD PMID:17374387 PMID:19272435 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clcn3 chloride voltage-gated channel 3 affects response to substance ISO CLCN3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Cldn2 claudin 2 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CLDN2 protein
resveratrol inhibits the reaction [Fluorouracil results in decreased expression of CLDN2 protein]		 CTD PMID:26310874 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cldn4 claudin 4 affects response to substance
decreases expression		 ISO CLDN4 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLDN4 protein		 CTD PMID:15352031 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Clec11a C-type lectin domain containing 11A affects response to substance
decreases expression		 ISO CLEC11A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CLEC11A protein		 CTD PMID:15352031 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633 		JBrowse link
G Clic1 chloride intracellular channel 1 affects response to substance ISO CLIC1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712 		JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO CLTC protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA] CTD PMID:15016801 PMID:18927307 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Coch cochlin affects response to substance ISO COCH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO Fluorouracil results in decreased expression of COL12A1 mRNA CTD PMID:15205334 PMID:16510598 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of COL1A1 mRNA; Fluorouracil results in decreased expression of COL1A1 protein
Fluorouracil promotes the reaction [Valsartan results in decreased expression of COL1A1 mRNA]; Valsartan promotes the reaction [Fluorouracil results in decreased expression of COL1A1 mRNA]		 CTD PMID:21296659 PMID:35235860 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression ISO Fluorouracil affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO Fluorouracil results in decreased expression of COL2A1 protein
Fluorouracil results in decreased expression of COL2A1 mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col3a1 collagen type III alpha 1 chain affects response to substance ISO COL3A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain affects response to substance
decreases expression		 ISO COL4A2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of COL4A2 protein		 CTD PMID:15352031 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col5a2 collagen type V alpha 2 chain affects response to substance ISO COL5A2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain affects response to substance
multiple interactions		 ISO COL6A3 protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Cox14 cytochrome c oxidase assembly factor COX14 affects expression ISO Fluorouracil affects the expression of COX14 mRNA CTD PMID:34151400 NCBI chr 7:130,852,226...130,854,316 JBrowse link
G Cox5b cytochrome c oxidase subunit 5B affects expression ISO Fluorouracil affects the expression of COX5B mRNA CTD PMID:34151400 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C affects expression ISO Fluorouracil affects the expression of COX6C mRNA CTD PMID:34151400 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963 		JBrowse link
G Cox7c cytochrome c oxidase subunit 7C affects expression ISO Fluorouracil affects the expression of COX7C mRNA CTD PMID:34151400 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760 		JBrowse link
G Cp ceruloplasmin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA] CTD PMID:15016801 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpa4 carboxypeptidase A4 decreases expression ISO Fluorouracil results in decreased expression of CPA4 mRNA CTD PMID:16510598 NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255 		JBrowse link
G Cpd carboxypeptidase D affects response to substance
multiple interactions		 ISO CPD protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491 		JBrowse link
G Cpe carboxypeptidase E affects response to substance
increases expression		 ISO CPE protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CPE protein		 CTD PMID:15352031 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects response to substance ISO CPT1A protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 affects expression ISO Fluorouracil affects the expression of CPXM1 mRNA CTD PMID:15205334 NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330 		JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 affects response to substance
increases expression		 ISO CRABP1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CRABP1 protein		 CTD PMID:15352031 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 affects expression ISO Fluorouracil affects the expression of CRABP2 protein CTD PMID:21296659 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein affects expression ISO Fluorouracil affects the expression of CRHBP mRNA CTD PMID:15205334 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 affects response to substance
decreases expression
increases expression		 ISO CRIM1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CRIM1 mRNA
Fluorouracil results in increased expression of CRIM1 protein		 CTD PMID:15352031 PMID:16510598 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259 		JBrowse link
G Cripto cripto, EGF-CFC family member decreases expression ISO Fluorouracil results in decreased expression of CRIPTO protein
Fluorouracil results in decreased expression of CRIPTO mRNA		 CTD PMID:21296659 PMID:24737281 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein affects response to substance ISO CRK protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Crygs crystallin, gamma S multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA] CTD PMID:15016801 NCBI chr11:78,207,170...78,212,273
Ensembl chr11:78,207,170...78,212,273 		JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA] CTD PMID:15016801 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997 		JBrowse link
G Cryz crystallin zeta decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of CRYZ mRNA
TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA]		 CTD PMID:17982676 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cse1l chromosome segregation 1 like multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA] CTD PMID:15016801 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Csf1 colony stimulating factor 1 affects response to substance ISO CSF1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Fluorouracil results in increased expression of CSF2 mRNA CTD PMID:18344199 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csnk1e casein kinase 1, epsilon affects expression ISO Fluorouracil affects the expression of CSNK1E mRNA CTD PMID:16584549 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects response to substance ISO CSRP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Cst7 cystatin F affects response to substance
decreases expression		 ISO CST7 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of CST7 protein		 CTD PMID:15352031 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557 		JBrowse link
G Cst8 cystatin 8 affects expression ISO Fluorouracil affects the expression of CST8 mRNA CTD PMID:16584549 NCBI chr 3:136,244,586...136,255,412
Ensembl chr 3:136,244,636...136,251,273 		JBrowse link
G Cstf3 cleavage stimulation factor subunit 3 affects response to substance
increases expression		 ISO CSTF3 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CSTF3 mRNA		 CTD PMID:15331170 NCBI chr 3:90,966,415...91,037,669
Ensembl chr 3:90,966,354...91,042,196 		JBrowse link
G Ctbp2 C-terminal binding protein 2 multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNA; CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:16391804 PMID:18927307 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222 		JBrowse link
G Ctnnd2 catenin delta 2 multiple interactions ISO CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO Fluorouracil results in decreased expression of CTPS1 mRNA CTD PMID:19219653 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctsb cathepsin B multiple interactions
increases cleavage		 ISO CA 074 methyl ester inhibits the reaction [Fluorouracil results in increased cleavage of CTSB protein] CTD PMID:19816940 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsh cathepsin H affects response to substance
increases expression		 ISO CTSH protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CTSH protein		 CTD PMID:15352031 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Cttn cortactin decreases expression ISO Fluorouracil results in decreased expression of CTTN protein CTD PMID:15585135 PMID:16803524 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cul4a cullin 4A affects response to substance ISO CUL4A protein affects the susceptibility to Fluorouracil CTD PMID:16467204 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cul4b cullin 4B increases expression ISO Fluorouracil results in increased expression of CUL4B protein CTD PMID:16803524 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Cul5 cullin 5 increases expression ISO Fluorouracil results in increased expression of CUL5 mRNA CTD PMID:16557594 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Cutc cutC copper transporter affects response to substance
multiple interactions		 ISO CUTC protein affects the susceptibility to Fluorouracil
TP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA]		 CTD PMID:15016801 PMID:16217747 NCBI chr 1:242,622,281...242,637,048
Ensembl chr 1:242,622,276...242,637,047 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
affects expression		 ISO Fluorouracil results in increased expression of CXCL12 mRNA
Fluorouracil affects the expression of CXCL12 mRNA		 CTD PMID:16337237 PMID:18344199 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA] CTD PMID:27194111 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]; Bortezomib inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]
Fluorouracil results in increased expression of CXCL1 mRNA; Fluorouracil results in increased expression of CXCL1 protein		 CTD PMID:27194111 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO CXCR1 gene SNP affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:16098254 NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Fluorouracil affects the expression of CXCR4 mRNA CTD PMID:16584549 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA] CTD PMID:15016801 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA CTD PMID:32800223 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 affects response to substance
increases expression
multiple interactions		 ISO CYFIP2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of CYFIP2 mRNA
TP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]		 CTD PMID:15016801 PMID:16217747 PMID:17039268 PMID:17982676 NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases response to substance ISO CYLD protein results in increased susceptibility to Fluorouracil CTD PMID:21109933 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases metabolic processing EXP CYP1A1 protein results in increased metabolism of Fluorouracil CTD PMID:17230597 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Fluorouracil CTD PMID:10811482 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression ISO Fluorouracil affects the expression of CYP2F1 mRNA CTD PMID:16584549 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 affects expression ISO Fluorouracil affects the expression of CYP2S1 mRNA CTD PMID:20421339 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects expression ISO Fluorouracil affects the expression of CYP3A4 mRNA CTD PMID:16584549 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp51 cytochrome P450, family 51 affects response to substance ISO CYP51A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410 		JBrowse link
G Cyth3 cytohesin 3 decreases expression ISO Fluorouracil results in decreased expression of CYTH3 protein CTD PMID:15585135 PMID:16803524 NCBI chr12:10,840,137...10,933,792
Ensembl chr12:10,840,157...10,933,812 		JBrowse link
G Dapk1 death associated protein kinase 1 affects expression
increases expression		 ISO Fluorouracil affects the expression of DAPK1 mRNA
Fluorouracil results in increased expression of DAPK1 protein		 CTD PMID:20421339 PMID:30177839 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 affects expression ISO Fluorouracil affects the expression of DARS1 mRNA CTD PMID:16584549 NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO Fluorouracil results in decreased expression of DBF4 mRNA CTD PMID:16510598 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbndd2 dysbindin domain containing 2 affects response to substance ISO DBNDD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:153,216,300...153,220,651
Ensembl chr 3:153,191,090...153,220,651 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions ISO DCC protein results in increased susceptibility to [Fluorouracil co-treated with Levamisole] CTD PMID:15148649 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA] CTD PMID:15016801 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Dclk1 doublecortin-like kinase 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA] CTD PMID:15016801 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Dct dopachrome tautomerase affects expression ISO Fluorouracil affects the expression of DCT mRNA CTD PMID:15205334 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Dcx doublecortin decreases expression EXP Fluorouracil results in decreased expression of DCX protein CTD PMID:18702703 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA] CTD PMID:15016801 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent affects response to substance ISO DDAH2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 affects response to substance
multiple interactions
increases expression		 ISO DDB2 protein affects the susceptibility to Fluorouracil
TP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA]		 CTD PMID:15331170 PMID:16584549 PMID:17982676 PMID:22525470 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Fluorouracil results in increased expression of DDIT3 mRNA; Fluorouracil results in increased expression of DDIT3 protein CTD PMID:17355264 PMID:29879413 PMID:32535746 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Fluorouracil results in increased expression of DDIT4 mRNA CTD PMID:16510598 PMID:16557594 PMID:17039268 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx39b DExD-box helicase 39B increases expression ISO Fluorouracil results in increased expression of DDX39B mRNA CTD PMID:16510598 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Ddx4 DEAD-box helicase 4 increases expression ISO Fluorouracil results in increased expression of DDX4 protein CTD PMID:21296659 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Dennd2c DENN domain containing 2C affects expression ISO Fluorouracil affects the expression of DENND2C mRNA CTD PMID:20421339 NCBI chr 2:190,622,357...190,690,489
Ensembl chr 2:190,622,940...190,690,488 		JBrowse link
G Depdc7 DEP domain containing 7 affects expression ISO Fluorouracil affects the expression of DEPDC7 mRNA CTD PMID:20421339 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124 		JBrowse link
G Des desmin decreases expression ISO Fluorouracil results in decreased expression of DES protein CTD PMID:21296659 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Fluorouracil results in decreased expression of DFFA mRNA CTD PMID:34151400 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
G Dhfr dihydrofolate reductase affects expression
increases expression		 ISO Fluorouracil affects the expression of DHFR mRNA
Fluorouracil results in increased expression of DHFR mRNA		 CTD PMID:15109396 PMID:16557594 PMID:21814787 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression ISO Fluorouracil results in increased expression of DHX15 mRNA CTD PMID:16584549 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases response to substance
increases expression		 ISO DIABLO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of DIABLO mRNA		 CTD PMID:16557594 PMID:18031615 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Fluorouracil results in decreased expression of DICER1 mRNA CTD PMID:16510598 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dimt1 DIM1 rRNA methyltransferase and ribosome maturation factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA] CTD PMID:15016801 NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:38,354,854...38,368,227 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of DKK1 protein
DKK1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16217747 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO Fluorouracil results in increased expression of DKK4 mRNA CTD PMID:16584549 NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA] CTD PMID:15016801 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO DLG1 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog] CTD PMID:18927307 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 multiple interactions
increases expression		 ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA]
Fluorouracil results in increased expression of DLK1 mRNA		 CTD PMID:15016801 PMID:24737281 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dnah2 dynein, axonemal, heavy chain 2 decreases expression ISO Fluorouracil results in decreased expression of DNAH2 mRNA CTD PMID:24737281 NCBI chr10:54,142,648...54,268,901
Ensembl chr10:54,142,737...54,267,298 		JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO Fluorouracil results in increased expression of DNER mRNA CTD PMID:16510598 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO Fluorouracil results in decreased expression of DNMT3B protein CTD PMID:21296659 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpagt1 dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 affects response to substance ISO DPAGT1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:44,664,055...44,671,102
Ensembl chr 8:44,664,071...44,671,087 		JBrowse link
G Dpy19l1 dpy-19 like C-mannosyltransferase 1 affects response to substance ISO DPY19L1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases response to substance
multiple interactions
affects metabolic processing
affects response to substance
affects degradation
decreases metabolic processing
increases degradation
affects activity
increases expression
increases activity
decreases response to substance
increases metabolic processing
decreases expression		 ISO DPYD gene mutant form results in increased susceptibility to Fluorouracil; DPYD gene polymorphism results in increased susceptibility to Fluorouracil; DPYD mRNA results in increased susceptibility to Fluorouracil
[Cisplatin co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [docetaxel co-treated with Fluorouracil] results in decreased expression of DPYD mRNA; [Leucovorin co-treated with Fluorouracil] results in decreased activity of DPYD protein; Camptothecin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; Cisplatin inhibits the reaction [Fluorouracil results in increased expression of DPYD mRNA]; docetaxel inhibits the reaction [Fluorouracil results in increased activity of DPYD protein]; DPYD protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin]; DPYD results in increased susceptibility to [Fluorouracil co-treated with gimeracil]; Fluorouracil inhibits the reaction [docetaxel results in increased expression of DPYD protein]; gimeracil affects the reaction [DPYD protein results in increased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in decreased susceptibility to Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased degradation of Fluorouracil]; gimeracil inhibits the reaction [DPYD protein results in increased metabolism of Fluorouracil]
DPYD affects the metabolism of Fluorouracil; DPYD protein affects the metabolism of Fluorouracil
DPYD gene polymorphism affects the susceptibility to Fluorouracil; DPYD gene SNP affects the susceptibility to Fluorouracil; DPYD intron polymorphism affects the susceptibility to Fluorouracil; DPYD mRNA affects the susceptibility to Fluorouracil; DPYD promoter modified form affects the susceptibility to Fluorouracil; DPYD protein affects the susceptibility to Fluorouracil; DPYD protein mutant form affects the susceptibility to Fluorouracil
DPYD protein affects the degradation of Fluorouracil
DPYD gene polymorphism results in decreased metabolism of Fluorouracil; DPYD protein mutant form results in decreased metabolism of Fluorouracil
Fluorouracil metabolite affects the activity of DPYD protein
Fluorouracil results in increased expression of DPYD mRNA; Fluorouracil results in increased expression of DPYD protein
DPYD mRNA results in decreased susceptibility to Fluorouracil
DPYD mRNA results in decreased susceptibility to Fluorouracil; DPYD protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of DPYD mRNA		 CTD PMID:3335642 PMID:7503095 PMID:8680084 PMID:9470816 PMID:9816193 More... NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression ISO Fluorouracil affects the expression of DPYSL3 mRNA CTD PMID:15205334 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions
increases expression		 ISO TP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA]
Fluorouracil results in increased expression of DRAM1 protein
Fluorouracil promotes the reaction [Luteolin results in increased expression of DRAM1 protein]; Luteolin promotes the reaction [Fluorouracil results in increased expression of DRAM1 protein]		 CTD PMID:17982676 PMID:31288002 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765 		JBrowse link
G Drd5 dopamine receptor D5 multiple interactions ISO DRD5 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Dst dystonin affects response to substance ISO DST protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615 		JBrowse link
G Dtwd1 DTW domain containing 1 increases expression ISO Fluorouracil results in increased expression of DTWD1 mRNA CTD PMID:33770205 NCBI chr 3:113,392,402...113,409,322
Ensembl chr 3:113,392,457...113,408,105 		JBrowse link
G Dtymk deoxythymidylate kinase affects response to substance
increases expression
multiple interactions		 ISO DTYMK affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of DTYMK mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA]		 CTD PMID:15016801 PMID:15067352 PMID:15109396 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA] CTD PMID:15016801 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329 		JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA] CTD PMID:15016801 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Fluorouracil results in increased expression of DUSP6 mRNA CTD PMID:16510598 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dut deoxyuridine triphosphatase decreases response to substance
decreases expression		 ISO DUT protein results in decreased susceptibility to Fluorouracil
Fluorouracil results in decreased expression of DUT mRNA		 CTD PMID:16557594 PMID:19015155 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Fluorouracil results in decreased expression of E2F1 mRNA CTD PMID:34151400 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Fluorouracil results in decreased expression of E2F2; Fluorouracil results in decreased expression of E2F2 mRNA CTD PMID:11300326 PMID:34151400 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G E2f4 E2F transcription factor 4 multiple interactions
decreases expression		 ISO CDKN1A protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]; Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]; TP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]
Fluorouracil results in decreased expression of E2F4 mRNA		 CTD PMID:27129209 PMID:34151400 NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806 		JBrowse link
G E2f8 E2F transcription factor 8 affects expression ISO Fluorouracil affects the expression of E2F8 mRNA CTD PMID:16584549 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase affects response to substance ISO EBP protein affects the susceptibility to Fluorouracil CTD PMID:15548681 PMID:16217747 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 affects response to substance ISO ECHDC3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression ISO Fluorouracil results in increased expression of ECHS1 mRNA CTD PMID:15152939 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Ect2 epithelial cell transforming 2 multiple interactions
decreases expression		 ISO TP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA] CTD PMID:17982676 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 affects response to substance ISO EDIL3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Fluorouracil results in increased expression of EDN1 mRNA; Fluorouracil results in increased expression of EDN1 protein CTD PMID:1606078 PMID:19098008 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A affects response to substance ISO EDNRA protein affects the susceptibility to Fluorouracil CTD PMID:17032313 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B decreases expression ISO Fluorouracil results in decreased expression of EDNRB mRNA CTD PMID:24737281 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression
increases expression
multiple interactions		 ISO Fluorouracil affects the expression of EEF1A1 protein
Fluorouracil results in increased expression of EEF1A1 mRNA
TP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]		 CTD PMID:17982676 PMID:21296659 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 affects expression ISO Fluorouracil affects the expression of EEIG1 mRNA CTD PMID:16584549 NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Fluorouracil results in increased expression of EFEMP1 mRNA CTD PMID:24737281 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Efhd1 EF-hand domain family, member D1 affects response to substance ISO EFHD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Efhd2 EF-hand domain family, member D2 decreases expression ISO Fluorouracil results in decreased expression of EFHD2 mRNA CTD PMID:16510598 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980 		JBrowse link
G Efnb2 ephrin B2 affects response to substance
decreases expression		 ISO EFNB2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of EFNB2 protein		 CTD PMID:15352031 PMID:16217747 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Fluorouracil co-treated with EGF protein] results in increased expression of MT2A mRNA; EGF protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]]; MT2A protein affects the reaction [EGF protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]] CTD PMID:28507149 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor decreases response to substance
multiple interactions
affects response to substance
increases phosphorylation
decreases expression		 ISO EGFR gene polymorphism results in decreased susceptibility to Fluorouracil
[Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA; EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil]; EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil]; EGFR results in increased susceptibility to [Cisplatin co-treated with docetaxel co-treated with Fluorouracil]; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of EGFR protein; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein]
EGFR protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased phosphorylation of EGFR protein		 CTD PMID:15737843 PMID:15981280 PMID:16098254 PMID:16836928 PMID:17169374 More... NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 multiple interactions
decreases expression
increases expression
affects localization
affects expression		 ISO EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 mRNA]; EGR1 protein affects the reaction [Fluorouracil results in increased expression of THBS1 protein]; Fluorouracil promotes the reaction [EGR1 protein binds to THBS1 promoter]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 mRNA]; SB 203580 inhibits the reaction [Fluorouracil results in increased expression of EGR1 protein]
Fluorouracil results in decreased expression of EGR1 mRNA
Fluorouracil affects the localization of EGR1 protein
Fluorouracil affects the expression of EGR1 mRNA		 CTD PMID:15205334 PMID:16557594 PMID:17039268 PMID:18757417 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ehd2 EH-domain containing 2 affects response to substance ISO EHD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783 		JBrowse link
G Ehf ets homologous factor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA] CTD PMID:15016801 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression		 ISO Fluorouracil results in increased phosphorylation of EIF2AK3 protein
Fluorouracil results in increased expression of EIF2AK3 mRNA		 CTD PMID:29879413 PMID:32535746 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta decreases expression ISO Fluorouracil results in decreased expression of EIF2B2 protein CTD PMID:15585135 PMID:16803524 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Fluorouracil results in increased phosphorylation of EIF2S1 protein CTD PMID:29879413 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H increases expression ISO Fluorouracil results in increased expression of EIF3H protein CTD PMID:15585135 PMID:16803524 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of EIF4E mRNA
Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA]		 CTD PMID:15016801 PMID:15611226 PMID:16584549 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Fluorouracil inhibits the reaction [[CD40LG protein co-treated with CD40 protein] inhibits the reaction [EIF4E protein binds to EIF4EBP1 protein]] CTD PMID:15611226 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4h eukaryotic translation initiation factor 4H increases expression ISO Fluorouracil results in increased expression of EIF4H protein CTD PMID:15585135 PMID:16803524 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression ISO Fluorouracil results in increased expression of EIF5 mRNA CTD PMID:17039268 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA] CTD PMID:15016801 NCBI chr 6:45,388,451...45,502,089
Ensembl chr 6:45,388,376...45,502,083 		JBrowse link
G Elmo2 engulfment and cell motility 2 increases expression ISO Fluorouracil results in increased expression of ELMO2 protein CTD PMID:16803524 NCBI chr 3:154,023,661...154,061,259
Ensembl chr 3:154,023,661...154,061,185 		JBrowse link
G Eln elastin affects expression ISO Fluorouracil affects the expression of ELN mRNA CTD PMID:15205334 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Eloa elongin A affects expression ISO Fluorouracil affects the expression of ELOA mRNA CTD PMID:15205334 NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 affects response to substance ISO ELOVL5 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Emc1 ER membrane protein complex subunit 1 affects expression ISO Fluorouracil affects the expression of EMC1 mRNA CTD PMID:16584549 NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888 		JBrowse link
G Eml2 EMAP like 2 multiple interactions ISO EML2 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341 		JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Fluorouracil results in increased expression of EMP3 mRNA CTD PMID:19272435 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988 		JBrowse link
G Enah ENAH, actin regulator affects response to substance ISO ENAH protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr13:93,617,747...93,738,119
Ensembl chr13:93,626,944...93,740,955 		JBrowse link
G Endog endonuclease G increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of ENDOG protein
casticin inhibits the reaction [Fluorouracil results in increased expression of ENDOG protein]		 CTD PMID:32270916 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Enosf1 enolase superfamily member 1 affects response to substance
decreases response to substance		 ISO ENOSF1 protein affects the susceptibility to Fluorouracil
ENOSF1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:15548681 PMID:18357371 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 decreases expression ISO Fluorouracil results in decreased expression of ENTPD1 mRNA CTD PMID:19219653 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Entrep3 endosomal transmembrane epsin interactor 3 affects response to substance ISO ENTREP3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:174,588,984...174,595,281
Ensembl chr 2:174,589,337...174,595,281 		JBrowse link
G Eomes eomesodermin decreases expression ISO Fluorouracil results in decreased expression of EOMES protein CTD PMID:21296659 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Fluorouracil promotes the reaction [EP300 protein binds to UBE2C promoter] CTD PMID:27129209 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Ep400 E1A binding protein p400 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA] CTD PMID:15016801 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861 		JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 affects expression ISO Fluorouracil affects the expression of EPB41L3 mRNA CTD PMID:20421339 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Epha2 Eph receptor A2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA] CTD PMID:15016801 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ephx1 epoxide hydrolase 1 affects response to substance
increases expression		 ISO EPHX1 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPHX1 mRNA		 CTD PMID:15205334 PMID:16217747 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epo erythropoietin increases response to substance
increases expression		 ISO
EXP		 EPO protein results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of EPO protein		 CTD PMID:2206997 PMID:16103069 PMID:20020992 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor affects response to substance ISO EPOR gene mutant form affects the susceptibility to Fluorouracil CTD PMID:16511603 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Eppk1 epiplakin 1 increases expression ISO Fluorouracil results in increased expression of EPPK1 mRNA CTD PMID:16510598 NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 decreases expression ISO Fluorouracil results in decreased expression of EPRS1 mRNA CTD PMID:16709241 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Epyc epiphycan affects expression ISO Fluorouracil affects the expression of EPYC mRNA CTD PMID:15205334 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135 		JBrowse link
G Eras ES cell expressed Ras decreases expression ISO Fluorouracil results in decreased expression of ERAS protein CTD PMID:21296659 NCBI chr  X:14,573,987...14,578,455
Ensembl chr  X:14,573,987...14,578,374 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases response to substance
affects expression
affects response to substance		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; [Apigenin co-treated with Fluorouracil] results in decreased expression of ERBB2 protein; [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERBB2 mRNA; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein
ERBB2 mRNA results in decreased susceptibility to Fluorouracil; ERBB2 results in decreased susceptibility to Fluorouracil
Fluorouracil affects the expression of ERBB2 mRNA
ERBB2 mRNA alternative form affects the susceptibility to Fluorouracil		 CTD PMID:9816327 PMID:15205334 PMID:15737843 PMID:15940066 PMID:16446318 More... NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions ISO Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Fluorouracil results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein CTD PMID:17918158 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions
decreases expression		 ISO [Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA; ERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with Oxaliplatin]; ERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with Oxaliplatin]; ERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]; ERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil]
Fluorouracil results in decreased expression of ERCC1 mRNA		 CTD PMID:15173087 PMID:15213713 PMID:15737843 PMID:17016597 PMID:17401013 More... NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO ERCC2 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; ERCC2 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin] CTD PMID:15213713 PMID:17401013 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ereg epiregulin decreases expression ISO Fluorouracil results in decreased expression of EREG mRNA CTD PMID:16510598 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression ISO Fluorouracil results in increased expression of ERN1 mRNA CTD PMID:32535746 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression ISO Fluorouracil results in decreased expression of ERP29 protein CTD PMID:15585135 PMID:16803524 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase affects response to substance ISO ESPL1 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Etf1 eukaryotic translation termination factor 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA] CTD PMID:15016801 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects response to substance ISO ETFB protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression		 ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA]
Fluorouracil results in increased expression of ETS1 protein		 CTD PMID:15016801 PMID:30177839 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Etv2 ETS variant transcription factor 2 multiple interactions ISO Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431 		JBrowse link
G Exo1 exonuclease 1 affects response to substance ISO HEXO1 protein affects the susceptibility to Fluorouracil CTD PMID:16477629 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exosc10 exosome component 10 affects response to substance
increases metabolic processing		 ISO EXOSC10 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased metabolism of EXOSC10 protein		 CTD PMID:18567802 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G F12 coagulation factor XII affects response to substance
decreases expression		 ISO F12 protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of F12 protein		 CTD PMID:15352031 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F2 coagulation factor II, thrombin decreases expression ISO Fluorouracil results in decreased expression of F2 mRNA CTD PMID:16709241 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of F3 mRNA
F3 affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:16510598 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F8 coagulation factor VIII multiple interactions ISO F8 mRNA results in increased susceptibility to [Leucovorin co-treated with Fluorouracil co-treated with irinotecan] CTD PMID:17327601 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857 		JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Fluorouracil results in decreased expression of FABP7 mRNA CTD PMID:24737281 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fadd Fas associated via death domain decreases expression ISO Fluorouracil results in decreased expression of FADD mRNA CTD PMID:34151400 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fads1 fatty acid desaturase 1 affects response to substance ISO FADS1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fah fumarylacetoacetate hydrolase multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA] CTD PMID:15016801 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
G Fam107b family with sequence similarity 107, member B multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA] CTD PMID:15016801 NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989 		JBrowse link
G Fam114a1 family with sequence similarity 114, member A1 affects expression ISO Fluorouracil affects the expression of FAM114A1 mRNA CTD PMID:16584549 NCBI chr14:43,275,693...43,346,154
Ensembl chr14:43,275,701...43,346,174 		JBrowse link
G Fam171a1 family with sequence similarity 171, member A1 affects response to substance ISO FAM171A1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:75,024,582...75,148,348
Ensembl chr17:75,024,575...75,150,255 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression ISO Fluorouracil affects the expression of FAM20C mRNA CTD PMID:16584549 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fam234b family with sequence similarity 234, member B multiple interactions ISO FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:168,048,313...168,124,017
Ensembl chr 4:168,048,396...168,097,338 		JBrowse link
G Fam76b family with sequence similarity 76, member B decreases expression ISO Fluorouracil results in decreased expression of FAM76B mRNA CTD PMID:16510598 NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861 		JBrowse link
G Fancc FA complementation group C decreases expression ISO Fluorouracil results in decreased expression of FANCC mRNA CTD PMID:16557594 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376 		JBrowse link
G Fancg FA complementation group G increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of FANCG mRNA
FANCG affects the susceptibility to Fluorouracil; FANCG protein affects the susceptibility to Fluorouracil		 CTD PMID:15067352 PMID:15109396 PMID:15548681 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fanci FA complementation group I affects response to substance ISO FANCI protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640 		JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial decreases expression ISO Fluorouracil results in decreased expression of FARS2 mRNA CTD PMID:16101138 NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 ISO [Docosahexaenoic Acids co-treated with Fluorouracil] results in decreased expression of FAS mRNA; [Fluorouracil co-treated with RNF34 protein] results in increased expression of FAS protein; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP8 protein]; FAS protein affects the reaction [Fluorouracil results in increased activity of CASP9 protein]; N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]; TP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]; TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]
Fluorouracil results in increased expression of FAS; Fluorouracil results in increased expression of FAS mRNA; Fluorouracil results in increased expression of FAS protein		 CTD PMID:11300326 PMID:14665630 PMID:15016801 PMID:15034078 PMID:15152939 More... NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases response to substance
increases expression		 ISO FASL results in increased susceptibility to Fluorouracil
Fluorouracil results in increased expression of FASL		 CTD PMID:11196169 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fastk Fas-activated serine/threonine kinase decreases expression ISO Fluorouracil results in decreased expression of FASTK mRNA CTD PMID:34151400 NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430 		JBrowse link
G Fbln1 fibulin 1 affects expression
increases expression		 ISO Fluorouracil affects the expression of FBLN1 mRNA
Fluorouracil results in increased expression of FBLN1 mRNA		 CTD PMID:15205334 PMID:17039268 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Fluorouracil results in decreased expression of FBXO5 mRNA CTD PMID:16557594 PMID:19272435 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fdxr ferredoxin reductase multiple interactions
increases expression		 ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein]
Fluorouracil results in increased expression of FDXR mRNA; Fluorouracil results in increased expression of FDXR mRNA alternative form; Fluorouracil results in increased expression of FDXR protein		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:16557594 PMID:17982676 More... NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 affects response to substance
increases expression		 ISO FEN1 affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FEN1 mRNA		 CTD PMID:15067352 PMID:15109396 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects response to substance ISO FERMT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 affects response to substance ISO FGD6 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Fluorouracil results in decreased expression of FGF2 mRNA CTD PMID:16510598 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf4 fibroblast growth factor 4 affects expression ISO Fluorouracil affects the expression of FGF4 protein CTD PMID:21296659 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression ISO Fluorouracil results in decreased expression of FGF5 protein CTD PMID:21296659 NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997 		JBrowse link
G Fgf7 fibroblast growth factor 7 decreases response to substance
multiple interactions		 ISO FGF7 protein results in decreased susceptibility to Fluorouracil; FGF7 results in decreased susceptibility to Fluorouracil
FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil]		 CTD PMID:18575591 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO FGFR2 inhibits the reaction [FGF7 results in decreased susceptibility to Fluorouracil]; FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil] CTD PMID:18575591 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgg fibrinogen gamma chain decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of FGG mRNA
FGG protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:17039268 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fhl2 four and a half LIM domains 2 affects response to substance ISO FHL2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO Fluorouracil results in increased expression of FHL3 mRNA CTD PMID:17039268 NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317 		JBrowse link
G Fibcd1 fibrinogen C domain containing 1 decreases expression ISO Fluorouracil results in decreased expression of FIBCD1 mRNA CTD PMID:34151400 NCBI chr 3:15,092,682...15,126,371
Ensembl chr 3:15,092,681...15,126,399 		JBrowse link
G Filip1l filamin A interacting protein 1-like affects response to substance
increases expression		 ISO FILIP1L protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of FILIP1L protein		 CTD PMID:15352031 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 affects response to substance ISO FKBP11 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects response to substance ISO FKBP1B protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA] CTD PMID:15016801 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO Fluorouracil results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368 		JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 affects response to substance ISO FLRT2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of FLT1 protein
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein]		 CTD PMID:18157009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmod fibromodulin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA] CTD PMID:15016801 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Fluorouracil results in decreased expression of FN1 protein CTD PMID:21296659 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fnbp1 formin binding protein 1 affects response to substance ISO FNBP1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of FNDC3B mRNA
FNDC3B protein affects the susceptibility to Fluorouracil		 CTD PMID:16217747 PMID:16510598 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830 		JBrowse link
G Folr1 folate receptor alpha decreases expression ISO Fluorouracil results in decreased expression of FOLR1 mRNA CTD PMID:16510598 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
affects expression		 ISO Fluorouracil results in increased expression of FOS mRNA
Fluorouracil affects the expression of FOS mRNA		 CTD PMID:15205334 PMID:17039268 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects expression ISO Fluorouracil affects the expression of FOSL1 mRNA CTD PMID:34151400 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Fluorouracil results in decreased expression of FOXA2 protein CTD PMID:21296659 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxc1 forkhead box C1 affects expression ISO Fluorouracil affects the expression of FOXC1 mRNA CTD PMID:16584549 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxd3 forkhead box D3 decreases expression ISO Fluorouracil results in decreased expression of FOXD3 protein CTD PMID:21296659 NCBI chr 5:114,335,084...114,337,450
Ensembl chr 5:114,335,408...114,336,817 		JBrowse link
G Foxg1 forkhead box G1 decreases expression ISO Fluorouracil results in decreased expression of FOXG1 mRNA CTD PMID:30518710 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607 		JBrowse link
G Foxl2 forkhead box L2 increases expression ISO Fluorouracil results in increased expression of FOXL2 mRNA CTD PMID:34151400 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Fluorouracil results in decreased expression of FOXM1 mRNA CTD PMID:34151400 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxn3 forkhead box N3 decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of FOXN3 protein
FOXN3 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401 		JBrowse link
G Foxo3 forkhead box O3 affects response to substance ISO FOXO3 affects the susceptibility to Fluorouracil CTD PMID:15067352 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fpgs folylpolyglutamate synthase increases response to substance ISO FPGS protein results in increased susceptibility to Fluorouracil CTD PMID:15542523 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
G Fut1 fucosyltransferase 1 affects response to substance ISO FUT1 protein affects the susceptibility to Fluorouracil CTD PMID:15649251 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616 		JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 increases expression ISO Fluorouracil results in increased expression of FXYD3 mRNA CTD PMID:15152939 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase affects response to substance ISO FYN protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Fzd2 frizzled class receptor 2 affects response to substance ISO FZD2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G G0s2 G0/G1switch 2 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of G0S2 protein
G0S2 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression ISO Fluorouracil results in increased expression of GABRB3 protein CTD PMID:21296659 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
affects response to substance
increases response to substance
decreases expression		 ISO Fluorouracil results in increased expression of GADD45A mRNA; Fluorouracil results in increased expression of GADD45A protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]; TP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA]
GADD45A affects the susceptibility to Fluorouracil
GADD45A protein results in increased susceptibility to Fluorouracil
GADD45A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of GADD45A mRNA		 CTD PMID:15016801 PMID:15067352 PMID:15205334 PMID:16709241 PMID:16732331 More... NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases response to substance
multiple interactions
affects response to substance		 ISO GADD45B protein results in decreased susceptibility to Fluorouracil
IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]
GADD45B protein affects the susceptibility to Fluorouracil		 CTD PMID:16732331 PMID:17711513 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Fluorouracil results in increased expression of GADD45G mRNA CTD PMID:19272435 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Fluorouracil results in decreased expression of GAL protein CTD PMID:21296659 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 affects response to substance ISO GALNT3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase increases expression
multiple interactions
affects response to substance		 ISO Fluorouracil results in increased expression of GAMT protein
GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA]
GAMT protein affects the susceptibility to Fluorouracil		 CTD PMID:15016801 PMID:15352031 PMID:16896004 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects splicing
decreases expression		 ISO Fluorouracil affects the splicing of GAPDH mRNA
Fluorouracil results in decreased expression of GAPDH protein		 CTD PMID:17169984 PMID:21296659 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression ISO Fluorouracil results in increased expression of GART mRNA CTD PMID:19219653 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gast gastrin decreases response to substance ISO GAST protein modified form results in decreased susceptibility to Fluorouracil CTD PMID:16618411 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN mRNA]; Fluorouracil inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] CTD PMID:31404653 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gata4 GATA binding protein 4 affects expression ISO Fluorouracil affects the expression of GATA4 protein CTD PMID:21296659 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata6 GATA binding protein 6 affects expression ISO Fluorouracil affects the expression of GATA6 protein CTD PMID:21296659 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects response to substance ISO GCLM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcsh glycine cleavage system protein H multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA] CTD PMID:15016801 NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792 		JBrowse link
G Gdf1 growth differentiation factor 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA] CTD PMID:15016801 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of GDF15 mRNA; Fluorouracil results in increased expression of GDF15 protein
TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA]		 CTD PMID:14665630 PMID:15016801 PMID:15205334 PMID:24737281 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdf3 growth differentiation factor 3 affects expression ISO Fluorouracil affects the expression of GDF3 protein CTD PMID:21296659 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle affects expression ISO Fluorouracil affects the expression of GEM mRNA CTD PMID:15205334 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Fluorouracil results in increased expression of GFAP protein CTD PMID:21296659 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gins1 GINS complex subunit 1 increases response to substance ISO GINS1 gene mutant form results in increased susceptibility to Fluorouracil CTD PMID:18984863 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 affects expression ISO Fluorouracil affects the expression of GINS2 mRNA CTD PMID:16584549 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gja1 gap junction protein, alpha 1 affects response to substance ISO GJA1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 PMID:16531325 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjc1 gap junction protein, gamma 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA] CTD PMID:15016801 NCBI chr10:87,758,192...87,785,443
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gla galactosidase, alpha affects response to substance ISO GLA protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of GLI1 mRNA
GLI1 protein inhibits the reaction [Fluorouracil affects the localization of PTCH1 protein]		 CTD PMID:18776995 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Glipr1 GLI pathogenesis-related 1 increases expression ISO Fluorouracil results in increased expression of GLIPR1 mRNA CTD PMID:24737281 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429 		JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression ISO Fluorouracil results in decreased expression of GNB2 mRNA CTD PMID:16709241 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of GNE protein
GNE protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta affects expression ISO Fluorouracil affects the expression of GP1BB mRNA CTD PMID:16584549 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gpr132 G protein-coupled receptor 132 increases expression ISO Fluorouracil results in increased expression of GPR132 mRNA CTD PMID:16584549 NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168 		JBrowse link
G Gpr137c G protein-coupled receptor 137C affects expression ISO Fluorouracil affects the expression of GPR137C mRNA CTD PMID:16584549 NCBI chr15:18,425,939...18,492,588
Ensembl chr15:18,426,223...18,490,807 		JBrowse link
G Gpr35 G protein-coupled receptor 35 affects response to substance
increases expression		 ISO GPR35 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of GPR35 mRNA		 CTD PMID:15331170 NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299 		JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO Fluorouracil results in increased expression of GPR87 mRNA CTD PMID:24737281 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 ISO
EXP		 Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]
Fluorouracil results in increased activity of GPT protein
Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]		 CTD PMID:27836789 PMID:29678497 PMID:31129132 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
multiple interactions
decreases activity		 ISO
EXP		 Fluorouracil results in increased expression of GPX1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA]
Fluorouracil results in decreased activity of GPX1 protein		 CTD PMID:17982676 PMID:29117755 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA] CTD PMID:15016801 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
multiple interactions		 ISO
EXP		 Fluorouracil results in decreased expression of GPX4 protein
ferrostatin-1 inhibits the reaction [Fluorouracil results in decreased expression of GPX4 protein]		 CTD PMID:35101590 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gramd4 GRAM domain containing 4 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of GRAMD4 mRNA
TP73 protein promotes the reaction [Fluorouracil results in increased expression of GRAMD4 mRNA]		 CTD PMID:21127500 NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Grb7 growth factor receptor bound protein 7 increases expression ISO Fluorouracil results in increased expression of GRB7 protein CTD PMID:21296659 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 affects expression ISO Fluorouracil affects the expression of GRHL3 mRNA CTD PMID:16584549 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression ISO Fluorouracil affects the expression of GRINA mRNA CTD PMID:16584549 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Gspt1 G1 to S phase transition 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA] CTD PMID:15016801 NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Fluorouracil results in decreased activity of GSR protein CTD PMID:32752303 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 affects response to substance ISO GSTA4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA CTD PMID:32800223 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of GSTP1 mRNA
[Cisplatin co-treated with Fluorouracil] results in decreased expression of GSTP1 mRNA; GSTP1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]; GSTP1 gene polymorphism results in decreased susceptibility to [Fluorouracil co-treated with Cisplatin]		 CTD PMID:15205334 PMID:15213713 PMID:15737843 PMID:16622263 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression ISO Fluorouracil results in increased expression of GSTT1 protein CTD PMID:15585135 PMID:16803524 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gtpbp4 GTP binding protein 4 affects response to substance ISO GTPBP4 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 decreases expression ISO Fluorouracil results in decreased expression of GUCY1B1 mRNA CTD PMID:19219653 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G H1f0 H1.0 linker histone affects expression ISO Fluorouracil affects the expression of H1F0 mRNA CTD PMID:20421339 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694 		JBrowse link
G H2ax H2A.X variant histone affects expression
increases phosphorylation
multiple interactions		 ISO Fluorouracil affects the expression of H2AX mRNA
Fluorouracil results in increased phosphorylation of H2AX protein
[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein; [S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased expression of H2AX protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]; TP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein]]; TP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AX mRNA]		 CTD PMID:15016801 PMID:16584549 PMID:25940438 PMID:26544897 PMID:34510228 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression
increases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of H2BC12 mRNA
Fluorouracil results in increased expression of H2BC12 protein
H2BC12 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 PMID:16101138 PMID:16217747 NCBI chr17:42,485,699...42,486,162 JBrowse link
G H3-7l H3.7 histone like decreases expression ISO Fluorouracil results in decreased expression of H3-7 mRNA CTD PMID:16101138 NCBI chr 7:100,253,160...100,257,870 JBrowse link
G H4c14 H4 clustered histone 14 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of H4C2 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of H4C2 mRNA]		 CTD PMID:15016801 PMID:17039268 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048 		JBrowse link
G H4f3 H1.3 linker histone, cluster member increases expression ISO Fluorouracil results in increased expression of H1-3 protein CTD PMID:15585135 NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334 		JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 affects response to substance ISO HACD1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA] CTD PMID:15016801 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 increases expression ISO Fluorouracil results in increased expression of HAND2 mRNA CTD PMID:24737281 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hapln2 hyaluronan and proteoglycan link protein 2 affects expression ISO Fluorouracil affects the expression of HAPLN2 mRNA CTD PMID:16584549 NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA] CTD PMID:15016801 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta affects splicing ISO Fluorouracil affects the splicing of HBB mRNA CTD PMID:17169984 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain increases expression ISO Fluorouracil results in increased expression of HBB-B2 protein CTD PMID:21296659 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbe1 hemoglobin subunit epsilon 1 decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of HBE1 protein
HBE1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 1:158,282,931...158,458,855
Ensembl chr 1:158,282,936...158,284,391 		JBrowse link
G Hbz hemoglobin subunit zeta decreases expression ISO Fluorouracil results in decreased expression of HBZ protein CTD PMID:21296659 NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312 		JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC1 protein] CTD PMID:25178657 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions
increases response to substance		 ISO [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of MBP mRNA]]; [HDAC1 protein co-treated with HDAC2 protein] promotes the reaction [TCF7L2 protein inhibits the reaction [Fluorouracil results in decreased expression of OLIG2 mRNA]]; Fluorouracil inhibits the reaction [TCF7L2 protein binds to HDAC2 protein]
HDAC2 protein results in increased susceptibility to Fluorouracil		 CTD PMID:25178657 PMID:35608750 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO Fluorouracil results in decreased expression of HDAC3 mRNA CTD PMID:19272435 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO Fluorouracil results in decreased expression of HDAC4 mRNA CTD PMID:16557594 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO Fluorouracil results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072 		JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO Fluorouracil results in increased expression of HDAC9 mRNA CTD PMID:24737281 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hdgfl3 HDGF like 3 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA] CTD PMID:15016801 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA] CTD PMID:15016801 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases activity ISO Fluorouracil results in increased activity of HES1 protein CTD PMID:19147571 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Fluorouracil results in increased expression of HGF mRNA CTD PMID:24737281 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hic2 HIC ZBTB transcriptional repressor 2 affects response to substance ISO HIC2 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects localization
multiple interactions
decreases response to substance
affects response to substance
decreases uptake
decreases expression
increases expression		 ISO
EXP		 Fluorouracil affects the localization of HIF1A protein
Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Cyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil]
Fluorouracil results in decreased susceptibility to HIF1A protein; HIF1A results in decreased susceptibility to Fluorouracil
HIF1A protein affects the susceptibility to Fluorouracil
Fluorouracil results in decreased expression of HIF1A protein
Fluorouracil results in increased expression of HIF1A mRNA
[diacerein co-treated with Fluorouracil] inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein]; Fluorouracil inhibits the reaction [Trichloroacetic Acid results in increased expression of HIF1A protein]		 CTD PMID:16628086 PMID:17066447 PMID:17219956 PMID:27163855 PMID:34794354 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 increases expression ISO Fluorouracil results in increased expression of HINT1 protein CTD PMID:15585135 PMID:16803524 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Hk2 hexokinase 2 decreases expression
multiple interactions
affects response to substance		 ISO Fluorouracil results in decreased expression of HK2 protein
HK2 protein affects the reaction [Fluorouracil results in increased activity of CASP3 protein]
HK2 protein affects the susceptibility to Fluorouracil		 CTD PMID:16595493 PMID:18772588 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hm13 histocompatibility minor 13 affects expression ISO Fluorouracil affects the expression of HM13 mRNA CTD PMID:16584549 NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific affects response to substance ISO HMCES protein affects the susceptibility to Fluorouracil CTD PMID:15548681 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO Fluorouracil results in decreased expression of HMG20B mRNA CTD PMID:16709241 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA] CTD PMID:15016801 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 increases expression ISO Fluorouracil results in increased expression of HMGN5 mRNA CTD PMID:16510598 NCBI chr  X:74,085,871...74,094,488
Ensembl chr  X:74,085,875...74,094,441
Ensembl chr 1:74,085,875...74,094,441 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA] CTD PMID:15016801 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression		 ISO
EXP		 Fluorouracil results in increased expression of HMOX1
Fluorouracil affects the expression of HMOX1 mRNA		 CTD PMID:20722640 PMID:22954530 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf1a HNF1 homeobox A affects expression ISO Fluorouracil affects the expression of HNF1A mRNA CTD PMID:34151400 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha affects expression ISO Fluorouracil affects the expression of HNF4A mRNA CTD PMID:34151400 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 decreases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of HNRNPA1 mRNA
TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA]		 CTD PMID:15016801 PMID:16101138 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA] CTD PMID:15016801 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C increases expression ISO Fluorouracil results in increased expression of HNRNPC protein CTD PMID:15585135 PMID:16803524 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA] CTD PMID:15016801 NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA] CTD PMID:15016801 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA] CTD PMID:15016801 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Hoxa1 homeobox A1 decreases expression ISO Fluorouracil results in decreased expression of HOXA1 mRNA CTD PMID:24737281 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hoxb3 homeo box B3 decreases expression ISO Fluorouracil results in decreased expression of HOXB3 mRNA CTD PMID:24737281 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107 		JBrowse link
G Hoxc11 homeobox C11 affects expression
affects response to substance		 ISO Fluorouracil affects the expression of HOXC11 protein
HOXC11 protein affects the susceptibility to Fluorouracil		 CTD PMID:15331170 NCBI chr 7:134,091,224...134,094,738
Ensembl chr 7:134,091,552...134,094,738 		JBrowse link
G Hoxd1 homeo box D1 decreases expression ISO Fluorouracil results in decreased expression of HOXD1 mRNA CTD PMID:24737281 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769 		JBrowse link
G Hpx hemopexin multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA] CTD PMID:15016801 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Fluorouracil results in increased expression of HRAS mRNA CTD PMID:16557594 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 decreases expression ISO Fluorouracil results in decreased expression of HS6ST2 mRNA CTD PMID:16510598 NCBI chr  X:130,966,547...131,261,629
Ensembl chr  X:130,968,385...131,261,492 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects expression ISO Fluorouracil affects the expression of HSD17B2 mRNA CTD PMID:16584549 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of HSPA1B protein
HSPA1B protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of HSPA2 mRNA
HSPA2 protein affects the susceptibility to Fluorouracil		 CTD PMID:16101138 PMID:16217747 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of HSPA4 protein
HSPA4 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Fluorouracil results in decreased expression of HSPA5 mRNA; Fluorouracil results in decreased expression of HSPA5 protein CTD PMID:29879413 PMID:32535746 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects response to substance ISO HSPA8 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
decreases response to substance		 ISO HSPB1 protein affects the susceptibility to [Cisplatin co-treated with Fluorouracil co-treated with Leucovorin]
HSPB1 protein results in decreased susceptibility to Fluorouracil		 CTD PMID:18949417 PMID:19088045 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases phosphorylation
multiple interactions		 ISO Fluorouracil results in increased phosphorylation of HSPB2 protein
SB 203580 inhibits the reaction [Fluorouracil results in increased phosphorylation of HSPB2 protein]		 CTD PMID:18757417 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression ISO Fluorouracil results in increased expression of HSPB8 mRNA CTD PMID:16557594 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Fluorouracil results in increased expression of HSPE1 mRNA CTD PMID:15152939 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions
increases response to substance		 ISO [Fluorouracil co-treated with irinotecan] results in increased expression of HTATIP2 mRNA
HTATIP2 protein results in increased susceptibility to Fluorouracil		 CTD PMID:16391804 PMID:16799960 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects expression ISO Fluorouracil affects the expression of HTR7 mRNA CTD PMID:16584549 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression
affects response to substance		 ISO Fluorouracil results in increased expression of HTRA1 protein
HTRA1 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Iapp islet amyloid polypeptide decreases expression ISO Fluorouracil results in decreased expression of IAPP protein CTD PMID:21296659 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression
multiple interactions		 ISO Fluorouracil results in increased expression of ID1 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID1 mRNA]		 CTD PMID:16557594 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
affects response to substance
increases expression
multiple interactions		 ISO Fluorouracil results in decreased expression of ID2 protein
ID2 protein affects the susceptibility to Fluorouracil
Fluorouracil results in increased expression of ID2 mRNA
TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]		 CTD PMID:15016739 PMID:15352031 PMID:16557594 PMID:25178657 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO Fluorouracil results in increased expression of ID3 mRNA CTD PMID:15205334 PMID:16557594 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects response to substance ISO IDI1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO TP53 protein affects the reaction [Fluorouracil results in increased expression of IER5 mRNA] CTD PMID:15016801 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A multiple interactions ISO [Fluorouracil co-treated with irinotecan] results in increased expression of IFI27L2 mRNA CTD PMID:16391804 NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO Fluorouracil results in increased expression of IFI35 mRNA CTD PMID:16101138 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Fluorouracil results in increased expression of IFIT2 mRNA CTD PMID:16101138 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression
increases expression		 ISO Fluorouracil results in decreased expression of IFITM1 protein
Fluorouracil results in increased expression of IFITM1 mRNA		 CTD PMID:16101138 PMID:16510598 PMID:17039268 PMID:21296659 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression ISO Fluorouracil results in increased expression of IFITM2 protein CTD PMID:21296659 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Ifna1 interferon, alpha 1 increases response to substance
increases abundance
multiple interactions		 ISO IFNA1 protein results in increased susceptibility to Fluorouracil
IFNA1 protein results in increased abundance of Fluorouracil
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of RGS5 mRNA]
[Fluorouracil co-treated with IFNA1 protein] results in decreased expression of BCL2L1 mRNA; [Fluorouracil co-treated with IFNA1 protein] results in decreased expression of CFLAR protein; ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein]; ANGPT2 protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]; Fluorouracil promotes the reaction [IFNA1 protein results in increased expression of TP53AIP1 mRNA]; IFNA1 promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 mRNA]; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein]; IFNA1 promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of CFLAR mRNA]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP3 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP8 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]; IFNA1 protein promotes the reaction [Fluorouracil results in increased expression of BAX mRNA]; IFNA1 protein promotes the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]; VEGFA protein promotes the reaction [Fluorouracil results in decreased expression of IFNA1 protein]		 CTD PMID:16101138 PMID:16568373 PMID:17016659 PMID:17045692 PMID:17786339 More... NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 increases expression ISO Fluorouracil results in increased expression of IFNAR1 mRNA; Fluorouracil results in increased expression of IFNAR1 protein CTD PMID:17088986 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 increases expression ISO Fluorouracil results in increased expression of IFNAR2 mRNA; Fluorouracil results in increased expression of IFNAR2 protein CTD PMID:16101138 PMID:17088986 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases response to substance		 ISO [Fluorouracil co-treated with IFNB1 protein] results in increased activity of CASP3 protein
IFNB1 protein results in increased susceptibility to Fluorouracil		 CTD PMID:15937643 PMID:16101138 PMID:18608205 PMID:18695887 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma multiple interactions
increases abundance
decreases expression		 ISO [IFNG protein results in increased expression of TYMP protein] which results in increased susceptibility to Fluorouracil; Fluorouracil promotes the reaction [IL18 protein modified form results in increased expression of IFNG protein]; IFNG protein inhibits the reaction [GADD45B protein results in decreased susceptibility to Fluorouracil]
IFNG protein results in increased abundance of Fluorouracil
LCS101 inhibits the reaction [Fluorouracil results in decreased expression of IFNG protein]		 CTD PMID:15162350 PMID:15301717 PMID:15754409 PMID:16568373 PMID:17711513 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression
multiple interactions		 EXP
ISO		 Fluorouracil results in increased expression of IGF1 mRNA
[Fluorouracil co-treated with IGF1 protein] results in increased expression of MT2A mRNA; IGF1 protein inhibits the reaction [Fluorouracil results in decreased expression of MT2A protein]; IGF1 protein inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 mRNA]; IGF1 protein inhibits the reaction [Fluorouracil results in increased expression of XAF1 protein]		 CTD PMID:16888818 PMID:28507149 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein]; Fluorouracil results in decreased phosphorylation of and results in decreased activity of IGF1R protein CTD PMID:17918158 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Fluorouracil results in increased expression of IGFBP2 protein CTD PMID:21296659 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Fluorouracil results in decreased expression of IGFBP5 mRNA CTD PMID:16557594 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression
affects response to substance		 ISO Fluorouracil results in decreased expression of IGFBP6 protein
IGFBP6 protein affects the susceptibility to Fluorouracil		 CTD PMID:15352031 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Ihh Indian hedgehog signaling molecule decreases expression ISO Fluorouracil results in decreased expression of IHH mRNA; Fluorouracil results in decreased expression of IHH protein CTD PMID:25190613 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532