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ONTOLOGY REPORT - ANNOTATIONS


Term:diosmin
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Accession:CHEBI:4631 term browser browse the term
Definition:A disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Synonyms:exact_synonym: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
 related_synonym: 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside;   3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside;   Diosmetin 7-O-rutinoside;   Formula=C28H32O15;   InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1;   InChIKey=GZSOSUNBTXMUFQ-YFAPSIMESA-N;   SMILES=COc1ccc(cc1O)-c1cc(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2o1;   diosmetin 7-neohesperidoside;   diosmine;   diosminum;   neodiosmin
 xref: CAS:520-27-4 "ChemIDplus";   CAS:520-27-4 "KEGG COMPOUND";   Drug_Central:3157 "DrugCentral";   KEGG:C10039;   KEGG:D07858;   KNApSAcK:C00004362;   LINCS:LSM-5989;   LIPID_MAPS_instance:LMPK12110819 "LIPID MAPS"
 xref_mesh: MESH:D004145
 xref: PMID:25620156 "Europe PMC";   PMID:25821971 "Europe PMC";   Reaxys:74883 "Reaxys";   Wikipedia:Diosmin


show annotations for term's descendants       view all columns           Sort by:
 
diosmin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19617
    role 19560
      chemical role 19052
        antioxidant 13677
          diosmin 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19617
    subatomic particle 19613
      composite particle 19613
        hadron 19613
          baryon 19613
            nucleon 19613
              atomic nucleus 19613
                atom 19613
                  main group element atom 19491
                    p-block element atom 19491
                      carbon group element atom 19363
                        carbon atom 19355
                          organic molecular entity 19355
                            organic molecule 19272
                              organic cyclic compound 19062
                                organic heterocyclic compound 18129
                                  oxacycle 16870
                                    benzopyran 9418
                                      1-benzopyran 9112
                                        flavonoid 6232
                                          flavones 4140
                                            hydroxyflavone 4129
                                              3'-hydroxyflavonoid 193
                                                luteolin 145
                                                  diosmetin 27
                                                    diosmin 16
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.