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ONTOLOGY REPORT - ANNOTATIONS


Term:coenzyme Q10
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Accession:CHEBI:46245 term browser browse the term
Definition:A ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration.
Synonyms:exact_synonym: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
 related_synonym: 2-((all-E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;   2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone;   Adelir;   CoQ;   CoQ10;   Formula=C59H90O4;   InChI=1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+;   InChIKey=ACTIUHUUMQJHFO-UPTCCGCDSA-N;   Q;   Q 199;   Q10;   SMILES=COC1=C(OC)C(=O)C(C\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CC\\C=C(/C)CCC=C(C)C)=C(C)C1=O;   Ubidecarenone;   all-trans-ubiquinone;   ubiquinone;   ubiquinone 10;   ubiquinone 50
 alt_id: CHEBI:46241;   CHEBI:9854
 xref: Beilstein:1900141 "Beilstein";   CAS:303-98-0 "ChemIDplus";   CAS:303-98-0 "KEGG COMPOUND";   Drug_Central:4607 "DrugCentral";   HMDB:HMDB0001072;   KEGG:C11378;   KEGG:D01065;   KNApSAcK:C00002866;   LIPID_MAPS_instance:LMPR02010001 "LIPID MAPS"
 xref_mesh: MESH:C024989
 xref: PDBeChem:U10;   PMID:10953455 "Europe PMC";   PMID:13445756 "Europe PMC";   PMID:17192765 "Europe PMC";   PMID:17605305 "Europe PMC";   PMID:18787645 "Europe PMC";   PMID:18843432 "Europe PMC";   PMID:20367194 "Europe PMC";   PMID:25544601 "Europe PMC";   PMID:26741866 "Europe PMC";   PMID:27012265 "Europe PMC";   PMID:7599208 "Europe PMC";   PMID:7718355 "Europe PMC";   Reaxys:1900141 "Reaxys";   Wikipedia:Coenzyme_Q10


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coenzyme Q10 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 JBrowse link 14 48,726,033 48,922,809 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G C1qa complement C1q A chain JBrowse link 5 155,261,254 155,264,101 RGD:6480464
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:6480464
G Etv3 ETS variant transcription factor 3 JBrowse link 2 186,872,483 186,887,294 RGD:6480464
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Ncoa2 nuclear receptor coactivator 2 JBrowse link 5 5,466,544 5,696,540 RGD:6480464
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 JBrowse link 5 56,567,109 56,576,676 RGD:6480464
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 JBrowse link 7 12,318,776 12,326,403 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:6480464
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6480464
G Pou2f1 POU class 2 homeobox 1 JBrowse link 13 84,075,316 84,217,368 RGD:6480464
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:6480464
G Psd3 pleckstrin and Sec7 domain containing 3 JBrowse link 16 23,212,165 23,789,414 RGD:6480464
G Skap2 src kinase associated phosphoprotein 2 JBrowse link 4 81,816,778 81,968,832 RGD:6480464
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      chemical role 19209
        antioxidant 14108
          coenzyme Q10 48
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18427
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18305
                                    carbonyl compound 18305
                                      ketone 15922
                                        cyclic ketone 13359
                                          quinone 8238
                                            benzoquinones 589
                                              1,4-benzoquinones 584
                                                monohydroxy-1,4-benzoquinones 63
                                                  2-hydroxy-5-methylquinone 57
                                                    2,3-dihydroxy-5-methyl-1,4-benzoquinone 57
                                                      ubiquinones 57
                                                        coenzyme Q10 48
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.