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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:L-tyrosinal
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Accession:CHEBI:46209 term browser browse the term
Definition:An amino aldehyde that is L-tyrosine in which the carboxy group has undergone formal redution to give the corrresponding aldehyde
Synonyms:exact_synonym: (2S)-2-amino-3-(4-hydroxyphenyl)propanal
 related_synonym: (2S)-2-amino-3-(p-hydroxyphenyl)propanal;   Formula=C9H11NO2;   InChI=1S/C9H11NO2/c10-8(6-11)5-7-1-3-9(12)4-2-7/h1-4,6,8,12H,5,10H2/t8-/m0/s1;   InChIKey=DXGAIOIQACHYRK-QMMMGPOBSA-N;   L-tyr aldehyde;   SMILES=O=C[C@@H](N)CC=1C=CC(=CC1)O;   TYROSINAL
 alt_id: CHEBI:46188
 xref: MetaCyc:CPD-21526;   PDBeChem:TYB;   PMID:23281040
 cyclic_relationship: is_conjugate_base_of CHEBI:141668


show annotations for term's descendants           Sort by:
 
alpha-methyl-L-dopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation
decreases activity
ISO COMT protein results in increased methylation of Methyldopa
Methyldopa results in decreased activity of COMT protein
CTD PMID:7053299 PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTA1 protein CTD PMID:8131222 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTM1 protein CTD PMID:8131222 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTP1 protein CTD PMID:8131222 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Prl prolactin increases expression
increases secretion
ISO Methyldopa results in increased expression of PRL protein
Methyldopa results in increased secretion of PRL protein
CTD PMID:1867878 PMID:7265421 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ren renin decreases activity EXP Methyldopa results in decreased activity of REN protein CTD PMID:145319 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
Leu-enkephalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp3 dipeptidylpeptidase 3 increases cleavage
multiple interactions
ISO DPP3 protein results in increased cleavage of Enkephalin, Leucine
spinorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]; tynorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]
CTD PMID:10873616 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541
JBrowse link
G Oprd1 opioid receptor, delta 1 increases activity ISO Enkephalin, Leucine results in increased activity of OPRD1 protein CTD PMID:26476280 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprm1 opioid receptor, mu 1 increases activity ISO Enkephalin, Leucine results in increased activity of OPRM1 protein CTD PMID:26476280 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        refrigerant 17694
          ammonia 17278
            organic amino compound 17278
              primary amino compound 7952
                L-tyrosinal 9
                  L-tyrosine + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            formyl group 8789
                                              aldehyde 8789
                                                amino aldehyde 644
                                                  L-tyrosinal 9
                                                    L-tyrosine + 9
paths to the root