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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:46209 term browser browse the term
Definition:An amino aldehyde that is L-tyrosine in which the carboxy group has undergone formal redution to give the corrresponding aldehyde
Synonyms:exact_synonym: (2S)-2-amino-3-(4-hydroxyphenyl)propanal
 related_synonym: (2S)-2-amino-3-(p-hydroxyphenyl)propanal;   Formula=C9H11NO2;   InChI=1S/C9H11NO2/c10-8(6-11)5-7-1-3-9(12)4-2-7/h1-4,6,8,12H,5,10H2/t8-/m0/s1;   InChIKey=DXGAIOIQACHYRK-QMMMGPOBSA-N;   L-tyr aldehyde;   SMILES=O=C[C@@H](N)CC=1C=CC(=CC1)O;   TYROSINAL
 alt_id: CHEBI:46188
 xref: MetaCyc:CPD-21526;   PDBeChem:TYB;   PMID:23281040
 cyclic_relationship: is_conjugate_base_of CHEBI:141668

show annotations for term's descendants           Sort by:
alpha-methyl-L-dopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation
decreases activity
ISO COMT protein results in increased methylation of Methyldopa
Methyldopa results in decreased activity of COMT protein
CTD PMID:7053299, PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTA1 protein CTD PMID:8131222 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTM1 protein CTD PMID:8131222 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTP1 protein CTD PMID:8131222 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Prl prolactin increases expression
increases secretion
ISO Methyldopa results in increased expression of PRL protein
Methyldopa results in increased secretion of PRL protein
CTD PMID:1867878, PMID:7265421 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ren renin decreases activity EXP Methyldopa results in decreased activity of REN protein CTD PMID:145319 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        refrigerant 17439
          ammonia 16959
            organic amino compound 16958
              primary amino compound 7872
                L-tyrosinal 6
                  L-tyrosine + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        carboacyl group 17372
                                          univalent carboacyl group 17372
                                            formyl group 7851
                                              aldehyde 7851
                                                amino aldehyde 593
                                                  L-tyrosinal 6
                                                    L-tyrosine + 6
paths to the root


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