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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Dimethyl phthalate
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Accession:CHEBI:4609 term browser browse the term
Definition:A phthalate ester that has formula C10H10O4.
Synonyms:related_synonym: Formula=C10H10O4;   InChI=1S/C10H10O4/c1-13-9(11)7-5-3-4-6-8(7)10(12)14-2/h3-6H,1-2H3;   InChIKey=NIQCNGHVCWTJSM-UHFFFAOYSA-N;   SMILES=COC(=O)c1ccccc1C(=O)OC
 xref: CAS:131-11-3;   Drug_Central:4771;   KEGG:C11233
 xref_mesh: MESH:C024629
 xref: PPDB:2989;   VSDB:2989


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Dimethyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP dimethyl phthalate binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ar androgen receptor multiple interactions ISO dimethyl phthalate analog inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; dimethyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:20943248 PMID:28571686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression EXP dimethyl phthalate results in increased expression of BAK1 mRNA CTD PMID:35598668 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BAX mRNA CTD PMID:35598668 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BCL2 mRNA CTD PMID:35598668 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP dimethyl phthalate results in increased expression of BID mRNA CTD PMID:35598668 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp2 caspase 2 increases expression EXP dimethyl phthalate results in increased expression of CASP2 mRNA CTD PMID:35598668 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases expression EXP dimethyl phthalate results in increased expression of CASP3 mRNA CTD PMID:35598668 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases expression EXP dimethyl phthalate results in increased expression of CASP7 mRNA CTD PMID:35598668 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases expression EXP dimethyl phthalate results in increased expression of CASP8 mRNA CTD PMID:35598668 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP dimethyl phthalate results in increased expression of CYP11A1 mRNA CTD PMID:26472102 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP dimethyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP dimethyl phthalate results in decreased activity of CYP2B1 protein CTD PMID:27432241 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Fadd Fas associated via death domain increases expression EXP dimethyl phthalate results in increased expression of FADD mRNA CTD PMID:35598668 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP dimethyl phthalate results in increased expression of FAS mRNA CTD PMID:35598668 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression EXP dimethyl phthalate results in increased expression of FASLG mRNA CTD PMID:35598668 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Ifng interferon gamma decreases expression EXP dimethyl phthalate results in decreased expression of IFNG protein CTD PMID:35598668 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP dimethyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il4 interleukin 4 decreases expression EXP dimethyl phthalate results in decreased expression of IL4 protein CTD PMID:35598668 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 decreases expression EXP dimethyl phthalate results in decreased expression of IL6 protein CTD PMID:35598668 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP dimethyl phthalate results in decreased expression of MSH2 mRNA CTD PMID:26472102 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Myocd myocardin decreases expression EXP dimethyl phthalate results in decreased expression of MYOCD mRNA CTD PMID:26472102 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects binding ISO dimethyl phthalate binds to NR1I3 protein CTD PMID:25938866 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO dimethyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO dimethyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO dimethyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO dimethyl phthalate binds to RXRA protein CTD PMID:23843199 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO dimethyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO dimethyl phthalate binds to RXRG protein CTD PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP dimethyl phthalate results in decreased expression of SCARB1 mRNA CTD PMID:26472102 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP dimethyl phthalate results in decreased expression of SOD1 protein CTD PMID:35598668 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP dimethyl phthalate results in decreased expression of STAR mRNA CTD PMID:26472102 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      application 19687
        fuel 11327
          methanol 3949
            methyl ester 3896
              Dimethyl phthalate 32
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic group 18962
                              organic divalent group 18943
                                organodiyl group 18915
                                  carbonyl group 18869
                                    carbonyl compound 18869
                                      carboxylic acid 18618
                                        aromatic carboxylic acid 12023
                                          benzoic acids 11998
                                            benzenedicarboxylic acid 7894
                                              phthalic acid 7642
                                                phthalate ester 7629
                                                  Dimethyl phthalate 32
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