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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:46020 term browser browse the term
Definition:The simplest quaternary ammonium cation, comprising a central nitrogen linked to four methyl groups.
Synonyms:exact_synonym: N,N,N-trimethylmethanaminium
 related_synonym: (CH3)4N(+);   Formula=C4H12N;   InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1;   InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N;   SMILES=C[N+](C)(C)C;   TETRAMETHYLAMMONIUM ION;   [NMe4](+);   tetramethylazanium;   trimethylaminomethane
 alt_id: CHEBI:35264;   CHEBI:46018
 xref: Beilstein:1733140;   CAS:51-92-3;   DrugBank:DB03095;   Gmelin:1858
 xref_mesh: MESH:C027917
 xref: PDBeChem:TMA;   PMID:10421447;   PMID:10788331;   Reaxys:1733140;   Wikipedia:Tetramethylammonium

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tetramethylammonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCHE butyrylcholinesterase decreases activity EXP tetramethylammonium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
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G SLC47A1 solute carrier family 47 member 1 multiple interactions EXP
tetramethylammonium affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; tetramethylammonium inhibits the reaction [SLC47A1 protein affects the uptake of Paraquat] CTD PMID:17495125 PMID:22419765 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24775
    chemical entity 24745
      molecular entity 24712
        ion 17258
          organic ion 8792
            organic cation 7525
              quaternary ammonium ion 5196
                tetramethylammonium 2
                  tetramethylammonium bromide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 24775
    subatomic particle 24735
      composite particle 24735
        hadron 24735
          baryon 24735
            nucleon 24735
              atomic nucleus 24735
                atom 24735
                  main group element atom 24601
                    main group molecular entity 24601
                      s-block molecular entity 23907
                        hydrogen molecular entity 23745
                          hydrides 21962
                            inorganic hydride 19168
                              pnictogen hydride 19141
                                nitrogen hydride 18819
                                  ammonium 8050
                                    ammonium ion derivative 8046
                                      quaternary ammonium ion 5196
                                        tetramethylammonium 2
                                          tetramethylammonium bromide 0
paths to the root