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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:46020 term browser browse the term
Definition:The simplest quaternary ammonium cation, comprising a central nitrogen linked to four methyl groups.
Synonyms:exact_synonym: N,N,N-trimethylmethanaminium
 related_synonym: (CH3)4N(+);   Formula=C4H12N;   InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1;   InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N;   SMILES=C[N+](C)(C)C;   TETRAMETHYLAMMONIUM ION;   [NMe4](+);   tetramethylazanium;   trimethylaminomethane
 alt_id: CHEBI:35264;   CHEBI:46018
 xref: Beilstein:1733140;   CAS:51-92-3;   DrugBank:DB03095;   Gmelin:1858
 xref_mesh: MESH:C027917
 xref: PDBeChem:TMA;   PMID:10421447;   PMID:10788331;   Reaxys:1733140;   Wikipedia:Tetramethylammonium

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tetramethylammonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO tetramethylammonium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO
tetramethylammonium affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; tetramethylammonium inhibits the reaction [SLC47A1 protein affects the uptake of Paraquat] CTD PMID:17495125 PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      molecular entity 20071
        ion 16485
          organic ion 9208
            organic cation 8144
              quaternary ammonium ion 5131
                tetramethylammonium 2
                  tetramethylammonium bromide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    main group molecular entity 19971
                      s-block molecular entity 19765
                        hydrogen molecular entity 19756
                          hydrides 19120
                            inorganic hydride 17878
                              pnictogen hydride 17861
                                nitrogen hydride 17747
                                  ammonium 8250
                                    ammonium ion derivative 8246
                                      quaternary ammonium ion 5131
                                        tetramethylammonium 2
                                          tetramethylammonium bromide 0
paths to the root