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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:46020 term browser browse the term
Definition:The simplest quaternary ammonium cation, comprising a central nitrogen linked to four methyl groups.
Synonyms:exact_synonym: N,N,N-trimethylmethanaminium
 related_synonym: (CH3)4N(+);   Formula=C4H12N;   InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1;   InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N;   SMILES=C[N+](C)(C)C;   TETRAMETHYLAMMONIUM ION;   [NMe4](+);   tetramethylazanium;   trimethylaminomethane
 alt_id: CHEBI:35264;   CHEBI:46018
 xref: Beilstein:1733140;   CAS:51-92-3;   DrugBank:DB03095;   Gmelin:1858
 xref_mesh: MESH:C027917
 xref: PDBeChem:TMA;   PMID:10421447;   PMID:10788331;   Reaxys:1733140;   Wikipedia:Tetramethylammonium

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tetramethylammonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO tetramethylammonium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO
tetramethylammonium affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; tetramethylammonium inhibits the reaction [SLC47A1 protein affects the uptake of Paraquat] CTD PMID:17495125 PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      molecular entity 19770
        ion 15945
          organic ion 8455
            organic cation 7309
              quaternary ammonium ion 5098
                tetramethylammonium 2
                  tetramethylammonium bromide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    main group molecular entity 19658
                      s-block molecular entity 19423
                        hydrogen molecular entity 19416
                          hydrides 18755
                            inorganic hydride 17460
                              pnictogen hydride 17435
                                nitrogen hydride 17281
                                  ammonium 8216
                                    ammonium ion derivative 8212
                                      quaternary ammonium ion 5098
                                        tetramethylammonium 2
                                          tetramethylammonium bromide 0
paths to the root