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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzothiazole
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Accession:CHEBI:45993 term browser browse the term
Definition:An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.
Synonyms:exact_synonym: 1,3-benzothiazole
 related_synonym: 1-Thia-3-azaindene;   BT;   Benzosulfonazole;   Benzothiazol;   Formula=C7H5NS;   InChI=1S/C7H5NS/c1-2-4-7-6(3-1)8-5-9-7/h1-5H;   InChIKey=IOJUPLGTWVMSFF-UHFFFAOYSA-N;   SMILES=c1ccc2scnc2c1
 xref: Beilstein:109468;   CAS:95-16-9;   DrugBank:DB08624;   HMDB:HMDB0032930
 xref_mesh: MESH:C005465
 xref: PDBeChem:THZ;   PMID:15750776;   PMID:18568896;   PMID:23500410;   PMID:24248888;   Reaxys:109468;   UM-BBD_compID:c1128;   Wikipedia:Benzothiazole


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benzothiazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects binding ISO benzothiazole binds to AHR protein; benzothiazole metabolite binds to AHR protein CTD PMID:16705413 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP benzothiazole results in increased expression of EPHX1 mRNA CTD PMID:8951341 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP benzothiazole results in increased expression of GSTA2 mRNA CTD PMID:8951341 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP benzothiazole results in increased expression of GSTM1 mRNA CTD PMID:8951341 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP benzothiazole results in increased expression of GSTM2 mRNA CTD PMID:8951341 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19908
    role 19883
      biological role 19881
        xenobiotic 18772
          benzothiazole 5
            2-hydroxybenzothiazole 0
            2-methylthio-1,3-benzothiazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19908
    subatomic particle 19906
      composite particle 19906
        hadron 19906
          baryon 19906
            nucleon 19906
              atomic nucleus 19906
                atom 19906
                  main group element atom 19853
                    p-block element atom 19853
                      carbon group element atom 19799
                        carbon atom 19794
                          organic molecular entity 19794
                            organic molecule 19751
                              organic cyclic compound 19559
                                organic heterocyclic compound 18896
                                  organic heteropolycyclic compound 18317
                                    organic heterobicyclic compound 17269
                                      benzothiazoles 149
                                        benzothiazole 5
                                          2-hydroxybenzothiazole 0
                                          2-methylthio-1,3-benzothiazole 0
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