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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trifluoroacetic acid
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Accession:CHEBI:45892 term browser browse the term
Definition:A monocarboxylic acid that is the trifluoro derivative of acetic acid.
Synonyms:related_synonym: CF3COOH;   Formula=C2HF3O2;   InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7);   InChIKey=DTQVDTLACAAQTR-UHFFFAOYSA-N;   SMILES=OC(=O)C(F)(F)F;   TFA;   Trifluoressigsaeure;   acide trifluoroacetique;   perfluoroacetic acid
 alt_id: CHEBI:27111
 xref: Beilstein:742035;   CAS:76-05-1;   Gmelin:2729;   HMDB:HMDB0014118
 xref_mesh: MESH:D014269
 xref: PMID:11498800;   PMID:7696372;   Reaxys:742035;   Wikipedia:Trifluoroacetic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:27110


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trifluoroacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 multiple interactions ISO Acrylamide analog inhibits the reaction [Trifluoroacetic Acid results in increased degradation of FGF2 protein] CTD PMID:14733594 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions EXP Trifluoroacetic Acid binds to and results in decreased activity of NPY1R protein CTD PMID:16714086 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
valrubicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO valrubicin results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        reagent 17168
          trifluoroacetic acid 3
            N,O-bis(trimethylsilyl)trifluoroacetamide 0
            trifluoroacetamide + 1
            trifluoroacetyl chloride 0
            trifluoroacetyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          acetic acid 10697
                                            trifluoroacetic acid 3
                                              N,O-bis(trimethylsilyl)trifluoroacetamide 0
                                              trifluoroacetamide + 1
                                              trifluoroacetyl chloride 0
                                              trifluoroacetyl group 0
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