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ONTOLOGY REPORT - ANNOTATIONS


Term:troleandomycin
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Accession:CHEBI:45735 term browser browse the term
Definition:A semi-synthetic macrolide antibiotic obtained by acetylation of the three free hydroxy groups of oleandomycin. Troleandomycin is only found in individuals that have taken the drug.
Synonyms:exact_synonym: (3R,5R,6S,7R,8R,11R,12S,13R,14S,15S)-12-[(4-O-acetyl-2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-14-{[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadecan-6-yl acetate
 related_synonym: Formula=C41H67NO15;   InChI=1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41+/m0/s1;   InChIKey=LQCLVBQBTUVCEQ-QTFUVMRISA-N;   Oleandocetine;   Oleandomycin triacetate;   Oleandomycin triacetyl ester;   SMILES=CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3OC(C)=O)N(C)C)[C@@H](C)C[C@@]3(CO3)C(=O)[C@H](C)[C@@H](OC(C)=O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(C)=O;   Triacetyloleandomycin;   Triacetyloleandomycinum;   Tribiocillina;   Triocetin;   troleandomicina;   troleandomycine;   troleandomycinum
 alt_id: CHEBI:32267
 xref: CAS:2751-09-9 "ChemIDplus";   CAS:2751-09-9 "KEGG COMPOUND";   DrugBank:DB01361;   Drug_Central:2769 "DrugCentral";   HMDB:HMDB0015448;   KEGG:C12753;   KEGG:D01322;   LINCS:LSM-5510;   LIPID_MAPS_instance:LMPK04000042 "LIPID MAPS"
 xref_mesh: MESH:D014217
 xref: PDBeChem:TAO;   PMID:24335510 "Europe PMC";   PMID:24479850 "Europe PMC";   PMID:24889073 "Europe PMC";   PMID:24985121 "Europe PMC";   PMID:25392348 "Europe PMC";   PMID:25870103 "Europe PMC";   Reaxys:77547 "Reaxys";   Wikipedia:Troleandomycin


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troleandomycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 JBrowse link 7 12,918,352 12,922,509 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        xenobiotic 18178
          troleandomycin 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic ester 13934
                                        lactone 5859
                                          macrocyclic lactone 1515
                                            macrolide 1454
                                              oleandomycins 8
                                                oleandomycin 8
                                                  troleandomycin 8
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