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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:45716 term browser browse the term
Definition:A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Synonyms:exact_synonym: N-hydroxy-N'-phenyloctanediamide
 related_synonym: Formula=C14H20N2O3;   InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18);   InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N;   SAHA;   SHH;   SMILES=ONC(=O)CCCCCCC(=O)Nc1ccccc1;   Suberanilohydroxamic acid;   Zolinza;   octanedioic acid hydroxyamide phenylamide;   suberoylanilide hydroxamic acid;   vorinostatum
 xref: CAS:149647-78-9;   DrugBank:DB02546;   Drug_Central:4124;   HMDB:HMDB0015568;   KEGG:D06320;   LINCS:LSM-3828
 xref_mesh: MESH:C111237
 xref: PDBeChem:SHH;   PMID:21657958;   PMID:22887890;   PMID:23320102;   PMID:23348693;   PMID:23708756;   PMID:23758082;   PMID:23820962;   PMID:23864881;   Patent:CN102641261;   Patent:KR20110045493;   Patent:NZ592686;   Patent:US2011039937;   Patent:WO2008106524;   Reaxys:7213017;   Wikipedia:Vorinostat

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      CHEBI ontology 19659
        role 19634
          biological role 19633
            biochemical role 19388
              apoptosis inducer 13431
                vorinostat 2596
    Path 2
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      CHEBI ontology 19659
        subatomic particle 19658
          composite particle 19658
            hadron 19658
              baryon 19658
                nucleon 19658
                  atomic nucleus 19700
                    atom 19658
                      main group element atom 19607
                        p-block element atom 19607
                          carbon group element atom 19550
                            carbon atom 19547
                              organic molecular entity 19588
                                organic group 18752
                                  organic divalent group 18771
                                    organodiyl group 18737
                                      carbonyl group 18704
                                        carbonyl compound 18738
                                          carboxylic acid 18409
                                            carboacyl group 17570
                                              univalent carboacyl group 17599
                                                carbamoyl group 17407
                                                  carboxamide 17407
                                                    dicarboxylic acid amide 3148
                                                      dicarboxylic acid diamide 2696
                                                        vorinostat 2596
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