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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dicyclomine
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Accession:CHEBI:4514 term browser browse the term
Definition:The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Synonyms:exact_synonym: 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
 related_synonym: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate;   Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester;   Dicycloverin;   Formula=C19H35NO2;   InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3;   InChIKey=CURUTKGFNZGFSE-UHFFFAOYSA-N;   SMILES=CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1;   dicicloverina;   dicycloverine;   dicycloverinum
 alt_id: CHEBI:265774
 xref: Beilstein:2282819;   CAS:77-19-0;   DrugBank:DB00804;   Drug_Central:868;   KEGG:C06951;   KEGG:D07820;   LINCS:LSM-3534
 xref_mesh: MESH:D004025
 xref: Patent:US2474796;   Wikipedia:Dicyclomine


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dicyclomine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dicyclomine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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  CHEBI ontology 19812
    role 19761
      application 19471
        refrigerant 17691
          ammonia 17278
            organic amino compound 17278
              amine 7821
                tertiary amine 619
                  dicyclomine 1
                    dicyclomine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        amino alcohol 1035
                                          ethanolamines 800
                                            ethanolamine 77
                                              2-diethylaminoethanol 16
                                                dicyclomine 1
                                                  dicyclomine hydrochloride 0
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