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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dicyclomine
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Accession:CHEBI:4514 term browser browse the term
Definition:The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Synonyms:exact_synonym: 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
 related_synonym: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate;   Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester;   Dicycloverin;   Formula=C19H35NO2;   InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3;   InChIKey=CURUTKGFNZGFSE-UHFFFAOYSA-N;   SMILES=CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1;   dicicloverina;   dicycloverine;   dicycloverinum
 alt_id: CHEBI:265774
 xref: Beilstein:2282819;   CAS:77-19-0;   DrugBank:DB00804;   Drug_Central:868;   KEGG:C06951;   KEGG:D07820;   LINCS:LSM-3534
 xref_mesh: MESH:D004025
 xref: Patent:US2474796;   Wikipedia:Dicyclomine


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dicyclomine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dicyclomine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        refrigerant 17418
          ammonia 16940
            organic amino compound 16939
              amine 7602
                tertiary amine 616
                  dicyclomine 1
                    dicyclomine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        amino alcohol 882
                                          ethanolamines 769
                                            ethanolamine 61
                                              2-diethylaminoethanol 16
                                                dicyclomine 1
                                                  dicyclomine hydrochloride 0
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