|
G
|
Chrna2
|
cholinergic receptor nicotinic alpha 2 subunit
|
multiple interactions
|
ISO
|
n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]
|
CTD |
PMID:11821649 |
|
NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
|
|
G
|
Chrnb4
|
cholinergic receptor nicotinic beta 4 subunit
|
multiple interactions
|
ISO
|
n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]
|
CTD |
PMID:11821649 |
|
NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
|
|
|
G
|
Acaa2
|
acetyl-CoA acyltransferase 2
|
multiple interactions increases expression
|
EXP
|
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of ACAA2 mRNA di-n-pentyl phthalate results in increased expression of ACAA2 mRNA
|
CTD |
PMID:25055962 PMID:33983380 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249
|
|
G
|
Acox1
|
acyl-CoA oxidase 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of ACOX1 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
|
|
G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of ACSL1 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
|
|
G
|
Acsl3
|
acyl-CoA synthetase long-chain family member 3
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of ACSL3 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:80,115,112...80,164,627
|
|
G
|
Agtr1a
|
angiotensin II receptor, type 1a
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of AGTR1A mRNA; di-n-pentyl phthalate results in decreased expression of AGTR1A protein
|
CTD |
PMID:36715143 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
|
|
G
|
Akr1b8
|
aldo-keto reductase family 1, member B8
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of AKR1B8 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
decreases phosphorylation
|
EXP
|
di-n-pentyl phthalate results in decreased phosphorylation of AKT1 protein
|
CTD |
PMID:36715143 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
Angptl4
|
angiopoietin-like 4
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of ANGPTL4 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
|
|
G
|
Aqp7
|
aquaporin 7
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of AQP7 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
|
|
G
|
Ar
|
androgen receptor
|
affects binding multiple interactions
|
ISO
|
di-n-pentyl phthalate binds to AR protein di-n-pentyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
|
CTD |
PMID:14751673 PMID:15840436 PMID:28571686 PMID:33049310 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
|
|
G
|
Atp1a1
|
ATPase Na+/K+ transporting subunit alpha 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of ATP1A1 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of BCL2 mRNA; di-n-pentyl phthalate results in decreased expression of BCL2 protein
|
CTD |
PMID:33798595 PMID:36715143 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Bmp6
|
bone morphogenetic protein 6
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of BMP6 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
|
|
G
|
Cat
|
catalase
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CAT protein
|
CTD |
PMID:36715143 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Cort
|
cortistatin
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CORT protein
|
CTD |
PMID:36715143 |
|
NCBI chr 5:159,560,591...159,562,032
|
|
G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of CPT1A mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
|
|
G
|
Cpt1b
|
carnitine palmitoyltransferase 1B
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of CPT1B mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404
|
|
G
|
Cpt2
|
carnitine palmitoyltransferase 2
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of CPT2 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
|
|
G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
multiple interactions increases expression decreases expression
|
EXP
|
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11A1 mRNA di-n-pentyl phthalate results in increased expression of CYP11A1 mRNA di-n-pentyl phthalate results in decreased expression of CYP11A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11A1 protein
|
CTD |
PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 PMID:36715143 More...
|
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
|
|
G
|
Cyp11b2
|
cytochrome P450, family 11, subfamily b, polypeptide 2
|
decreases expression multiple interactions
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CYP11B1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11B1 protein [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B1 mRNA
|
CTD |
PMID:22112501 PMID:25055962 PMID:33983380 PMID:36715143 |
|
NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
|
|
G
|
Cyp11b3
|
cytochrome P450, family 11, subfamily b, polypeptide 3
|
decreases expression multiple interactions
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CYP11B2 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11B2 protein [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B2 mRNA
|
CTD |
PMID:22112501 PMID:25055962 PMID:33983380 PMID:36715143 |
|
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
|
|
G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
decreases activity decreases expression multiple interactions
|
EXP
|
di-n-pentyl phthalate results in decreased activity of CYP17A1 protein di-n-pentyl phthalate results in decreased expression of CYP17A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP17A1 protein [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA
|
CTD |
PMID:6829050 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 More...
|
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of CYP19A1 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
|
|
G
|
Cyp21a1
|
cytochrome P450, family 21, subfamily a, polypeptide 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CYP21A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP21A1 protein
|
CTD |
PMID:36715143 |
|
NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
|
|
G
|
Cyp27a1
|
cytochrome P450, family 27, subfamily a, polypeptide 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of CYP27A1 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
|
|
G
|
Cyp51
|
cytochrome P450, family 51
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of CYP51 mRNA
|
CTD |
PMID:26472102 PMID:33983380 |
|
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
|
|
G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
multiple interactions decreases expression
|
EXP
|
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of DHCR7 mRNA di-n-pentyl phthalate results in decreased expression of DHCR7 mRNA
|
CTD |
PMID:22112501 PMID:25055962 PMID:33983380 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
|
|
G
|
Ebp
|
EBP, cholestenol delta-isomerase
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of EBP mRNA
|
CTD |
PMID:26472102 PMID:33983380 |
|
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
|
|
G
|
Ehhadh
|
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of EHHADH mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
|
|
G
|
Esr1
|
estrogen receptor 1
|
affects binding multiple interactions
|
ISO
|
di-n-pentyl phthalate analog binds to ESR1 protein; di-n-pentyl phthalate binds to ESR1 protein di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Tamoxifen inhibits the reaction [di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein]
|
CTD |
PMID:15464722 PMID:15840436 PMID:20822795 PMID:28571686 PMID:33049310 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
|
G
|
Esr2
|
estrogen receptor 2
|
multiple interactions affects binding
|
ISO
|
di-n-pentyl phthalate binds to and results in decreased activity of ESR2 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein] di-n-pentyl phthalate analog binds to ESR2 protein
|
CTD |
PMID:15464722 PMID:15840436 PMID:28571686 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919
|
|
G
|
Fabp1
|
fatty acid binding protein 1
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of FABP1 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
|
|
G
|
Fads2
|
fatty acid desaturase 2
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of FADS2 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
|
|
G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
|
|
G
|
Fsd2
|
fibronectin type III and SPRY domain containing 2
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of FSD2 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472
|
|
G
|
Gata4
|
GATA binding protein 4
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of GATA4 mRNA
|
CTD |
PMID:22112501 |
|
NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
|
|
G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of GNRHR mRNA
|
CTD |
PMID:33798595 |
|
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
|
|
G
|
Gpx1
|
glutathione peroxidase 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of GPX1 protein
|
CTD |
PMID:36715143 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G
|
Grb14
|
growth factor receptor bound protein 14
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of GRB14 mRNA
|
CTD |
PMID:15728792 |
|
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
|
|
G
|
Hey1
|
hes-related family bHLH transcription factor with YRPW motif 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HEY1 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
|
|
G
|
Hmgcr
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HMGCR mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HMGCS1 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100
|
|
G
|
Hmgcs2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of HMGCS2 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:185,875,616...185,902,130
|
|
G
|
Hnf1a
|
HNF1 homeobox A
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HNF1A mRNA
|
CTD |
PMID:15728792 |
|
NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
|
|
G
|
Hoxa1
|
homeobox A1
|
multiple interactions
|
ISO
|
di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]
|
CTD |
PMID:23696197 |
|
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
|
|
G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HSD11B2 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
|
|
G
|
Hsd17b11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of HSD17B11 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
|
|
G
|
Hsd17b3
|
hydroxysteroid (17-beta) dehydrogenase 3
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HSD17B3 mRNA; di-n-pentyl phthalate results in decreased expression of HSD17B3 protein
|
CTD |
PMID:33798595 |
|
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
|
|
G
|
Hsd17b8
|
hydroxysteroid (17-beta) dehydrogenase 8
|
increases expression
|
EXP
|
di-n-pentyl phthalate results in increased expression of HSD17B8 mRNA
|
CTD |
PMID:19560483 PMID:26472102 |
|
NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
|
|
G
|
Hsd3b1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HSD3B1 mRNA; di-n-pentyl phthalate results in decreased expression of HSD3B1 protein
|
CTD |
PMID:33798595 PMID:36715143 |
|
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
|
|
G
|
Hsd3b3
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of HSD3B3 mRNA
|
CTD |
PMID:33983380 |
|
NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
|
|
G
|
Id1
|
inhibitor of DNA binding 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of ID1 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419
|
|
G
|
Igf1
|
insulin-like growth factor 1
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of IGF1 mRNA
|
CTD |
PMID:26472102 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
|
|
G
|
Igfbp7
|
insulin-like growth factor binding protein 7
|
decreases expression
|
EXP
|
di-n-pentyl phthalate results in decreased expression of IGFBP7 mRNA
|
CTD |
PMID:19560483 |
|
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
|
|
G
|
Inha
|
inhibin subunit alpha
|
multiple interactions decreases expression
|
EXP
|
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INHA mRNA di-n-pentyl phthalate results in decreased expression of INHA mRNA
|
CTD |
PMID:25055962 PMID:26472102 PMID:33983380 |
|
NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
|
|
G
|
Insig1
|
insulin induced gene 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of INSIG1 mRNA
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CTD |
PMID:15728792 PMID:33983380 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G
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Insl3
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insulin-like 3
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multiple interactions decreases expression
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EXP
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[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INSL3 mRNA di-n-pentyl phthalate results in decreased expression of INSL3 mRNA
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CTD |
PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26454885 PMID:33798595 PMID:33983380 More...
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NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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G
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Ldlr
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low density lipoprotein receptor
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of LDLR mRNA
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CTD |
PMID:15728792 PMID:33983380 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G
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Lhb
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luteinizing hormone subunit beta
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decreases expression decreases secretion
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EXP
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di-n-pentyl phthalate results in decreased expression of LHB mRNA di-n-pentyl phthalate results in decreased secretion of LHB protein
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CTD |
PMID:33798595 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G
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Lhcgr
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luteinizing hormone/choriogonadotropin receptor
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of LHCGR mRNA; di-n-pentyl phthalate results in decreased expression of LHCGR protein
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CTD |
PMID:15728792 PMID:33798595 PMID:33983380 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G
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Mc2r
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melanocortin 2 receptor
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of MC2R mRNA; di-n-pentyl phthalate results in decreased expression of MC2R protein
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CTD |
PMID:36715143 |
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NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488
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G
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Msh2
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mutS homolog 2
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decreases expression increases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of MSH2 mRNA di-n-pentyl phthalate results in increased expression of MSH2 mRNA
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CTD |
PMID:26472102 |
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NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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G
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Mvd
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mevalonate diphosphate decarboxylase
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of MVD mRNA
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CTD |
PMID:33983380 |
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NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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G
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Myocd
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myocardin
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of MYOCD mRNA
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CTD |
PMID:26472102 |
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NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
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G
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Nr0b1
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nuclear receptor subfamily 0, group B, member 1
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decreases expression multiple interactions
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EXP
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di-n-pentyl phthalate results in decreased expression of NR0B1 mRNA [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of NR0B1 mRNA
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CTD |
PMID:15728792 PMID:22112501 PMID:25055962 PMID:33983380 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G
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Nr1i2
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nuclear receptor subfamily 1, group I, member 2
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multiple interactions
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ISO
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di-n-pentyl phthalate binds to and results in increased activity of NR1I2 protein
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CTD |
PMID:33049310 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G
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Nr1i3
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nuclear receptor subfamily 1, group I, member 3
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affects binding increases activity
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ISO
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di-n-pentyl phthalate analog binds to NR1I3 protein; di-n-pentyl phthalate binds to NR1I3 protein di-n-pentyl phthalate results in increased activity of NR1I3 protein
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CTD |
PMID:25938866 PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G
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Nr4a1
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nuclear receptor subfamily 4, group A, member 1
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increases expression
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EXP
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di-n-pentyl phthalate results in increased expression of NR4A1 mRNA
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CTD |
PMID:15728792 |
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NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G
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Nr4a2
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nuclear receptor subfamily 4, group A, member 2
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of NR4A2 protein
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CTD |
PMID:36715143 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G
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Nr4a3
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nuclear receptor subfamily 4, group A, member 3
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of NR4A3 mRNA
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CTD |
PMID:19560483 |
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NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G
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Nr5a1
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nuclear receptor subfamily 5, group A, member 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of NR5A1 mRNA; di-n-pentyl phthalate results in decreased expression of NR5A1 protein
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CTD |
PMID:36715143 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G
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Nsdhl
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NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of NSDHL mRNA
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CTD |
PMID:19560483 PMID:33983380 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G
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Pck1
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phosphoenolpyruvate carboxykinase 1
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increases expression
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EXP
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di-n-pentyl phthalate results in increased expression of PCK1 mRNA
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CTD |
PMID:33983380 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G
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Pomc
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proopiomelanocortin
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of POMC protein
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CTD |
PMID:36715143 |
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NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G
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Ppara
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peroxisome proliferator activated receptor alpha
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affects binding
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ISO
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di-n-pentyl phthalate binds to PPARA protein
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CTD |
PMID:23843199 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G
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Ppard
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peroxisome proliferator-activated receptor delta
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affects binding
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ISO
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di-n-pentyl phthalate binds to PPARB protein
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CTD |
PMID:23843199 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G
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Pparg
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peroxisome proliferator-activated receptor gamma
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affects binding multiple interactions
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ISO
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di-n-pentyl phthalate binds to PPARG protein di-n-pentyl phthalate binds to and results in increased activity of PPARG protein
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CTD |
PMID:23843199 PMID:33049310 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G
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Rxra
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retinoid X receptor alpha
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affects binding
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ISO
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di-n-pentyl phthalate binds to RXRA protein
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CTD |
PMID:23843199 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G
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Rxrb
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retinoid X receptor beta
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affects binding
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ISO
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di-n-pentyl phthalate binds to RXRB protein
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CTD |
PMID:23843199 |
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NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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G
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Rxrg
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retinoid X receptor gamma
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affects binding
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ISO
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di-n-pentyl phthalate binds to RXRG protein
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CTD |
PMID:23843199 |
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NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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G
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Scarb1
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scavenger receptor class B, member 1
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multiple interactions decreases expression
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EXP
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[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SCARB1 mRNA di-n-pentyl phthalate results in decreased expression of SCARB1 mRNA; di-n-pentyl phthalate results in decreased expression of SCARB1 protein
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CTD |
PMID:19560483 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 PMID:36715143 More...
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G
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Scd
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stearoyl-CoA desaturase
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increases expression
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EXP
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di-n-pentyl phthalate results in increased expression of SCD mRNA
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CTD |
PMID:33983380 |
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NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G
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Shox1
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SHOX homeobox 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of RHOX10 mRNA
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CTD |
PMID:22112501 |
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NCBI chr X:116,688,163...116,695,111
Ensembl chr X:116,688,163...116,695,058
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G
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Sirt1
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sirtuin 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of SIRT1 protein
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CTD |
PMID:33798595 PMID:36715143 |
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NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
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G
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Slc27a2
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solute carrier family 27 member 2
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increases expression
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EXP
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di-n-pentyl phthalate results in increased expression of SLC27A2 mRNA
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CTD |
PMID:33983380 |
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NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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G
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Snx17
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sorting nexin 17
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multiple interactions
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EXP
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[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SNX17 mRNA
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CTD |
PMID:25055962 |
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NCBI chr 6:25,177,528...25,183,001
Ensembl chr 6:25,177,391...25,183,030
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G
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Sod1
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superoxide dismutase 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of SOD1 protein
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CTD |
PMID:36715143 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G
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Sox9
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SRY-box transcription factor 9
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of SOX9 mRNA
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CTD |
PMID:26472102 |
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NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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G
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Srd5a1
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steroid 5 alpha-reductase 1
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of SRD5A1 mRNA
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CTD |
PMID:19560483 |
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NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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G
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Star
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steroidogenic acute regulatory protein
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multiple interactions increases expression decreases expression
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EXP
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[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of STAR mRNA di-n-pentyl phthalate results in increased expression of STAR mRNA di-n-pentyl phthalate results in decreased expression of STAR mRNA; di-n-pentyl phthalate results in decreased expression of STAR protein
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CTD |
PMID:19560483 PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 PMID:36715143 More...
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G
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Svs5
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seminal vesicle secretory protein 5
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of SVS5 mRNA
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CTD |
PMID:15728792 |
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NCBI chr 3:152,996,146...152,997,756
Ensembl chr 3:152,996,146...152,997,756
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G
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Tcf21
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transcription factor 21
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of TCF21 mRNA
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CTD |
PMID:26472102 |
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NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
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G
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Wnt7a
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Wnt family member 7A
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decreases expression
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EXP
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di-n-pentyl phthalate results in decreased expression of WNT7A mRNA
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CTD |
PMID:33983380 |
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NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:123,863,108...123,908,981
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