CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 4-phenylbutylamine
Accession: CHEBI:44814
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Definition: A phenylalkylamine that is benzene in which one of the hydrogens is substituted by a 4-aminobutyl group.
Synonyms: exact_synonym: 4-phenylbutan-1-amine
related_synonym: 4-amino-1-phenylbutane; Formula=C10H15N; InChI=1S/C10H15N/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9,11H2; InChIKey=AGNFWIZBEATIAK-UHFFFAOYSA-N; SMILES=C=1(C=CC=CC1)CCCCN; benzenebutanamine
xref: CAS:13214-66-9; DrugBank:DB04311
xref_mesh: MESH:C121358
xref: PDBeChem:PBN; PMID:10425374; PMID:11106506; PMID:29716210; PMID:7051703
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Abcc4
ATP binding cassette subfamily C member 4
increases expression
ISO
4-phenylbutylamine results in increased expression of ABCC4 mRNA; 4-phenylbutylamine results in increased expression of ABCC4 protein
CTD
PMID:20395535
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Bbc3
Bcl-2 binding component 3
multiple interactions
EXP
4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]
CTD
PMID:24291486
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of DDIT3 protein]
CTD
PMID:30394307
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
multiple interactions
ISO
4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HERPUD1 protein]
CTD
PMID:30394307
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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Hmox1
heme oxygenase 1
multiple interactions
EXP
4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]
CTD
PMID:24291486
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HSPA5 protein]
CTD
PMID:30394307
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Trib3
tribbles pseudokinase 3
multiple interactions
EXP
4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of TRIB3 mRNA]
CTD
PMID:24291486
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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