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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
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Accession:CHEBI:44811 term browser browse the term
Definition:A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
Synonyms:exact_synonym: (2R)-2-acetoxy-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
 related_synonym: (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium hydroxide inner salt 4-oxide;   1-O-hexadecyl PAF;   1-O-hexadecyl-2-O-acetyl-sn-glycero-3-phosophocholine;   1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine;   1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine;   1-O-hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine;   1-O-hexadecyl-platelet-activating factor;   1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine;   C16 PAF;   C16:0 PAF;   Formula=C26H54NO7P;   InChI=1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1;   InChIKey=HVAUUPRFYPCOCA-AREMUKBSSA-N;   PAF;   SMILES=CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(C)=O;   platelet-activating factor;   platelet-activating factor C16
 xref: CAS:74389-68-7;   DrugBank:DB02261;   LIPID_MAPS_instance:LMGP01020046;   PDBeChem:PFS;   PMID:19075994;   PMID:19827129;   PMID:20431963;   PMID:21347278;   PMID:21804199;   PMID:22924390;   PMID:23169529;   Reaxys:3574588;   Wikipedia:Platelet-activating_factor


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Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pharmaceutical 19275
          drug 19275
            bronchoconstrictor agent 65
              2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                pnictogen oxoacid 10146
                                  phosphorus oxoacid 9033
                                    phosphoric acids 7795
                                      phosphoric acid 7795
                                        phosphoric acid derivative 7474
                                          phosphate 7474
                                            organic phosphate 7473
                                              phospholipid 289
                                                glycerophospholipid 196
                                                  glycerophosphocholine 115
                                                    alkylacylglycero-3-phosphocholine 29
                                                      alkyl,acyl-sn-glycero-3-phosphocholine 29
                                                        2-acyl-1-alkyl-sn-glycero-3-phosphocholine 29
                                                          2-acetyl-1-alkyl-sn-glycero-3-phosphocholine 29
                                                            2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 0
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