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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nimesulide
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Accession:CHEBI:44445 term browser browse the term
Definition:An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Synonyms:related_synonym: 4-NITRO-2-PHENOXYMETHANESULFONANILIDE;   Formula=C13H12N2O5S;   InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3;   InChIKey=HYWYRSMBCFDLJT-UHFFFAOYSA-N;   N-(4-nitro-2-phenoxyphenyl)methanesulfonamide;   SMILES=CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O
 alt_id: CHEBI:44440;   CHEBI:7574
 xref: Beilstein:2421175;   CAS:51803-78-2;   DrugBank:DB04743;   Drug_Central:1935;   KEGG:D01049;   LINCS:LSM-3718
 xref_mesh: MESH:C012655
 xref: PDBeChem:NIM;   PMID:18426087;   Reaxys:2421175;   VSDB:1893;   Wikipedia:Nimesulide


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nimesulide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase decreases expression EXP nimesulide results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP nimesulide results in decreased expression of ABAT mRNA CTD PMID:24136188 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP nimesulide results in decreased expression of ABCA1 mRNA CTD PMID:24136188 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression
ISO nimesulide results in decreased expression of ABCB1 protein
nimesulide results in increased expression of ABCB1 mRNA
CTD PMID:21745461 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression EXP nimesulide results in increased expression of ABCB6 mRNA CTD PMID:24136188 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO nimesulide results in increased expression of ABCC1 mRNA CTD PMID:21745461 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP nimesulide results in increased expression of ABCC2 mRNA CTD PMID:24136188 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP nimesulide results in increased expression of ABCC3 mRNA CTD PMID:24136188 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression EXP nimesulide results in increased expression of ABCE1 mRNA CTD PMID:24136188 NCBI chr19:31,867,960...31,892,863
Ensembl chr19:31,867,981...31,892,863
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity
decreases expression
ISO nimesulide results in decreased activity of ABCG2 protein
nimesulide results in decreased expression of ABCG2 protein
CTD PMID:18581209 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg3l2 ATP-binding cassette, subfamily G (WHITE), member 3-like 2 decreases expression EXP nimesulide results in decreased expression of ABCG3L2 mRNA CTD PMID:24136188 NCBI chr14:5,568,023...5,609,333 JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP nimesulide results in increased expression of ACAA1 mRNA CTD PMID:24136188 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP nimesulide results in increased expression of ACAA2 mRNA CTD PMID:24136188 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP nimesulide results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acly ATP citrate lyase decreases expression EXP nimesulide results in decreased expression of ACLY mRNA CTD PMID:24136188 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco1 aconitase 1 increases expression EXP nimesulide results in increased expression of ACO1 mRNA CTD PMID:24136188 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 increases expression EXP nimesulide results in increased expression of ACO2 mRNA CTD PMID:24136188 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP nimesulide results in increased expression of ACOT2 mRNA CTD PMID:24136188 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot7 acyl-CoA thioesterase 7 increases expression EXP nimesulide results in increased expression of ACOT7 mRNA CTD PMID:24136188 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl decreases expression EXP nimesulide results in decreased expression of ACOX3 mRNA CTD PMID:24136188 NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP nimesulide results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:82,284,719...82,326,771
Ensembl chr10:82,284,720...82,326,771
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP nimesulide results in decreased expression of ACSL1 mRNA CTD PMID:24136188 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP nimesulide results in increased expression of ACSL4 mRNA CTD PMID:24136188 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP nimesulide results in decreased expression of ACSL5 mRNA CTD PMID:24136188 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 decreases expression EXP nimesulide results in decreased expression of ADAMTS7 mRNA CTD PMID:24136188 NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655
JBrowse link
G Adck5 aarF domain containing kinase 5 increases expression EXP nimesulide results in increased expression of ADCK5 mRNA CTD PMID:24136188 NCBI chr 7:117,643,976...117,661,789
Ensembl chr 7:117,643,206...117,661,845
JBrowse link
G Add1 adducin 1 increases expression EXP nimesulide results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 decreases expression EXP nimesulide results in decreased expression of ADGRL2 mRNA CTD PMID:24136188 NCBI chr 2:258,792,838...258,997,145
Ensembl chr 2:258,792,839...258,997,145
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP nimesulide results in decreased expression of ADHFE1 mRNA CTD PMID:24136188 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP nimesulide results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adprm ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent increases expression EXP nimesulide results in increased expression of ADPRM mRNA CTD PMID:24136188 NCBI chr10:53,583,275...53,595,821
Ensembl chr10:53,583,276...53,595,827
JBrowse link
G Adrm1 adhesion regulating molecule 1 increases expression EXP nimesulide results in increased expression of ADRM1 mRNA CTD PMID:24136188 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Adsl adenylosuccinate lyase increases expression EXP nimesulide results in increased expression of ADSL mRNA CTD PMID:24136188 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328
JBrowse link
G Afm afamin decreases expression EXP nimesulide results in decreased expression of AFM mRNA CTD PMID:24136188 NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
JBrowse link
G Agt angiotensinogen decreases activity ISO nimesulide results in decreased activity of AGT CTD PMID:12065685 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression EXP nimesulide results in decreased expression of AGXT mRNA CTD PMID:24136188 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression EXP nimesulide results in decreased expression of AGXT2 mRNA CTD PMID:24136188 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression EXP nimesulide results in increased expression of AHSA1 mRNA CTD PMID:24136188 NCBI chr 6:111,296,168...111,304,224
Ensembl chr 6:111,296,417...111,304,224
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP nimesulide results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aig1 androgen-induced 1 increases expression EXP nimesulide results in increased expression of AIG1 mRNA CTD PMID:24136188 NCBI chr 1:7,816,841...8,038,805
Ensembl chr 1:7,816,838...8,038,665
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 increases expression EXP nimesulide results in increased expression of AIMP2 mRNA CTD PMID:24136188 NCBI chr12:12,738,784...12,748,345
Ensembl chr12:12,738,812...12,748,345
JBrowse link
G Ak4 adenylate kinase 4 decreases expression EXP nimesulide results in decreased expression of AK4 mRNA CTD PMID:24136188 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP nimesulide results in increased expression of AKR1A1 mRNA CTD PMID:24136188 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP nimesulide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP nimesulide results in increased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression EXP nimesulide results in increased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP nimesulide results in increased expression of ALAS1 mRNA CTD PMID:24136188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression EXP nimesulide results in decreased expression of ALCAM mRNA CTD PMID:24136188 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP nimesulide results in increased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP nimesulide results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression EXP nimesulide results in increased expression of ALG12 mRNA CTD PMID:24136188 NCBI chr 7:129,798,663...129,812,677
Ensembl chr 7:129,798,663...129,812,388
JBrowse link
G Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit increases expression EXP nimesulide results in increased expression of ALG14 mRNA CTD PMID:24136188 NCBI chr 2:224,851,352...224,931,461
Ensembl chr 2:224,851,383...224,931,459
JBrowse link
G Amy1a amylase, alpha 1A decreases expression EXP nimesulide results in decreased expression of AMY1A mRNA CTD PMID:24136188 NCBI chr 2:216,428,709...216,443,518
Ensembl chr 2:216,428,709...216,443,518
JBrowse link
G Ang angiogenin decreases expression EXP nimesulide results in decreased expression of ANG mRNA CTD PMID:24136188 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP nimesulide results in decreased expression of ANGPTL3 mRNA CTD PMID:24136188 NCBI chr 5:117,698,590...117,706,729
Ensembl chr 5:117,698,764...117,705,808
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO nimesulide results in increased expression of ANGPTL4 mRNA CTD PMID:19415698 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP nimesulide results in decreased expression of ANKH mRNA CTD PMID:24136188 NCBI chr 2:80,131,563...80,256,948
Ensembl chr 2:80,131,563...80,256,954
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP nimesulide results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:10,917,359...10,937,522
Ensembl chr 7:10,917,367...10,936,415
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP nimesulide results in decreased expression of ANPEP mRNA CTD PMID:24136188 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa3 annexin A3 decreases expression EXP nimesulide results in decreased expression of ANXA3 mRNA CTD PMID:24136188 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa4 annexin A4 increases expression EXP nimesulide results in increased expression of ANXA4 mRNA CTD PMID:24136188 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 decreases expression EXP nimesulide results in decreased expression of ANXA5 mRNA CTD PMID:24136188 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa7 annexin A7 increases expression EXP nimesulide results in increased expression of ANXA7 mRNA CTD PMID:24136188 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Aopep aminopeptidase O decreases expression EXP nimesulide results in decreased expression of AOPEP mRNA CTD PMID:24136188 NCBI chr17:507,389...825,062
Ensembl chr17:507,377...821,582
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP nimesulide results in increased expression of APEX1 mRNA CTD PMID:24136188 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP nimesulide results in decreased expression of APLP2 mRNA CTD PMID:24136188 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP nimesulide results in decreased expression of APMAP mRNA CTD PMID:24136188 NCBI chr 3:146,376,828...146,407,259
Ensembl chr 3:146,376,828...146,407,252
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression EXP nimesulide results in decreased expression of APOA5 mRNA CTD PMID:24136188 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO nimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein]; nimesulide inhibits the reaction [APOE results in increased abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:14966570 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apol3 apolipoprotein L, 3 decreases expression EXP nimesulide results in decreased expression of APOL3 mRNA CTD PMID:24136188 NCBI chr 7:118,685,022...118,694,016
Ensembl chr 7:118,685,022...118,694,015
JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP nimesulide results in increased expression of APRT mRNA CTD PMID:24136188 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp8 aquaporin 8 increases expression EXP nimesulide results in increased expression of AQP8 mRNA CTD PMID:24136188 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Areg amphiregulin multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of AREG mRNA]; nimesulide inhibits the reaction [LHB results in increased expression of AREG protein] CTD PMID:16888076 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP nimesulide results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression EXP nimesulide results in decreased expression of ARHGDIB mRNA CTD PMID:24136188 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression EXP nimesulide results in decreased expression of ARHGEF19 mRNA CTD PMID:24136188 NCBI chr 5:159,754,954...159,773,699
Ensembl chr 5:159,755,535...159,773,699
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP nimesulide results in increased expression of ARPC5L mRNA CTD PMID:24136188 NCBI chr 3:23,301,455...23,309,077
Ensembl chr 3:23,301,455...23,309,072
JBrowse link
G Arpin actin-related protein 2/3 complex inhibitor increases expression EXP nimesulide results in increased expression of ARPIN mRNA CTD PMID:24136188 NCBI chr 1:141,664,790...141,672,789
Ensembl chr 1:141,662,850...141,672,810
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP nimesulide results in increased expression of ARPP19 mRNA CTD PMID:24136188 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 decreases expression EXP nimesulide results in decreased expression of ASAP2 mRNA CTD PMID:24136188 NCBI chr 6:43,231,178...43,348,606
Ensembl chr 6:43,234,526...43,343,551
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression EXP nimesulide results in decreased expression of ASGR2 mRNA CTD PMID:24136188 NCBI chr10:56,710,446...56,723,608
Ensembl chr10:56,710,464...56,723,611
JBrowse link
G Aspg asparaginase decreases expression EXP nimesulide results in decreased expression of ASPG mRNA CTD PMID:24136188 NCBI chr 6:136,682,279...136,701,673
Ensembl chr 6:136,682,126...136,701,628
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP nimesulide results in increased expression of ATF4 mRNA CTD PMID:24136188 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP nimesulide results in increased expression of ATIC mRNA CTD PMID:24136188 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060
JBrowse link
G Atl2 atlastin GTPase 2 increases expression EXP nimesulide results in increased expression of ATL2 mRNA CTD PMID:24136188 NCBI chr 6:2,568,975...2,610,432
Ensembl chr 6:2,568,990...2,610,437
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP nimesulide results in decreased expression of ATP1B1 mRNA CTD PMID:24136188 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP nimesulide results in increased expression of ATPIF1 mRNA CTD PMID:24136188 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP nimesulide results in increased expression of ATP5MC1 mRNA CTD PMID:24136188 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression EXP nimesulide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B increases expression EXP nimesulide results in increased expression of ATP6V0B mRNA CTD PMID:24136188 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression EXP nimesulide results in increased expression of ATP6V0E1 mRNA CTD PMID:24136188 NCBI chr10:16,769,857...16,792,930
Ensembl chr10:16,769,666...16,792,909
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression EXP nimesulide results in increased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:78,168,117...78,171,265
Ensembl chr 4:78,168,117...78,171,265
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F increases expression EXP nimesulide results in increased expression of ATP6V1F mRNA CTD PMID:24136188 NCBI chr 4:56,744,563...56,747,657
Ensembl chr 4:56,744,561...56,747,656
JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 increases expression EXP nimesulide results in increased expression of ATP6V1G1 mRNA CTD PMID:24136188 NCBI chr 5:79,367,663...79,373,843
Ensembl chr 5:79,367,663...79,373,843
JBrowse link
G Atrn attractin decreases expression EXP nimesulide results in decreased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:123,434,409...123,567,922
Ensembl chr 3:123,434,409...123,567,918
JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor increases expression EXP nimesulide results in increased expression of AUP1 mRNA CTD PMID:24136188 NCBI chr 4:113,887,030...113,890,103
Ensembl chr 4:113,887,115...113,890,101
JBrowse link
G Aven apoptosis and caspase activation inhibitor increases expression EXP nimesulide results in increased expression of AVEN mRNA CTD PMID:24136188 NCBI chr 3:103,980,612...104,117,193
Ensembl chr 3:104,042,168...104,117,192
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP nimesulide results in decreased expression of AVPR1A mRNA CTD PMID:24136188 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression EXP nimesulide results in decreased expression of AXL mRNA CTD PMID:24136188 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B2m beta-2 microglobulin decreases expression EXP nimesulide results in decreased expression of B2M mRNA CTD PMID:24136188 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
decreases response to substance
ISO
EXP
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
BAK1 results in decreased susceptibility to nimesulide
CTD PMID:18349538 PMID:21745461 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Banf1 BAF nuclear assembly factor 1 increases expression EXP nimesulide results in increased expression of BANF1 mRNA CTD PMID:24136188 NCBI chr 1:220,744,195...220,746,224
Ensembl chr 1:220,744,195...220,746,224
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein] CTD PMID:21745461 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP nimesulide results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression EXP nimesulide results in decreased expression of BCAR1 mRNA CTD PMID:24136188 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein increases expression EXP nimesulide results in increased expression of BCCIP mRNA CTD PMID:24136188 NCBI chr 1:205,777,474...205,789,887
Ensembl chr 1:205,777,130...205,790,175
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
affects localization
ISO
EXP
nimesulide results in decreased expression of BCL2 mRNA; nimesulide results in decreased expression of BCL2 protein
nimesulide affects the localization of BCL2 protein
CTD PMID:18564172 PMID:19772912 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone increases expression EXP nimesulide results in increased expression of BCS1L mRNA CTD PMID:24136188 NCBI chr 9:81,868,158...81,872,201
Ensembl chr 9:81,868,265...81,872,197
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression EXP nimesulide results in decreased expression of BDH1 mRNA CTD PMID:24136188 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bet1 Bet1 golgi vesicular membrane trafficking protein increases expression EXP nimesulide results in increased expression of BET1 mRNA CTD PMID:24136188 NCBI chr 4:29,082,368...29,092,638
Ensembl chr 4:29,082,365...29,092,753
JBrowse link
G Bgn biglycan decreases expression EXP nimesulide results in decreased expression of BGN mRNA CTD PMID:24136188 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP nimesulide results in decreased expression of BHLHE40 mRNA CTD PMID:24136188 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP nimesulide results in decreased expression of BHMT mRNA CTD PMID:24136188 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 decreases expression EXP nimesulide results in decreased expression of BHMT2 mRNA CTD PMID:24136188 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of BID protein]; nimesulide results in increased cleavage of and results in increased activity of BID protein CTD PMID:19360361 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO nimesulide results in decreased expression of BIRC5 protein CTD PMID:16969492 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blvrb biliverdin reductase B increases expression EXP nimesulide results in increased expression of BLVRB mRNA CTD PMID:24136188 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression EXP nimesulide results in decreased expression of BMP1 mRNA CTD PMID:24136188 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP nimesulide results in increased expression of BNIP3 mRNA CTD PMID:24136188 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP nimesulide results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bola1 bolA family member 1 increases expression EXP nimesulide results in increased expression of BOLA1 mRNA CTD PMID:24136188 NCBI chr 2:198,338,114...198,339,130
Ensembl chr 2:198,338,114...198,339,130
JBrowse link
G Bola3 bolA family member 3 increases expression EXP nimesulide results in increased expression of BOLA3 mRNA CTD PMID:24136188 NCBI chr 4:115,046,693...115,056,140
Ensembl chr 4:115,046,693...115,056,140
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression EXP nimesulide results in increased expression of BOP1 mRNA CTD PMID:24136188 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP nimesulide results in decreased expression of BTG1 mRNA CTD PMID:24136188 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Bysl bystin-like increases expression EXP nimesulide results in increased expression of BYSL mRNA CTD PMID:24136188 NCBI chr 9:15,393,461...15,403,212
Ensembl chr 9:15,393,330...15,403,117
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 increases expression EXP nimesulide results in increased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:124,921,686...124,926,171
Ensembl chr  X:124,921,728...124,926,171
JBrowse link
G C1qa complement C1q A chain decreases expression EXP nimesulide results in decreased expression of C1QA mRNA CTD PMID:24136188 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C1qb complement C1q B chain multiple interactions
decreases expression
ISO
EXP
nimesulide inhibits the reaction [PTGS2 results in increased expression of C1QB mRNA]
nimesulide results in decreased expression of C1QB mRNA
CTD PMID:11810182 PMID:24136188 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qbp complement C1q binding protein increases expression EXP nimesulide results in increased expression of C1QBP mRNA CTD PMID:24136188 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C1qc complement C1q C chain decreases expression EXP nimesulide results in decreased expression of C1QC mRNA CTD PMID:24136188 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G C1s complement C1s decreases expression EXP nimesulide results in decreased expression of C1S mRNA CTD PMID:24136188 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C6 complement C6 decreases expression EXP nimesulide results in decreased expression of C6 mRNA CTD PMID:24136188 NCBI chr 2:54,460,333...54,533,801
Ensembl chr 2:54,466,280...54,533,797
JBrowse link
G C8a complement C8 alpha chain decreases expression EXP nimesulide results in decreased expression of C8A mRNA CTD PMID:24136188 NCBI chr 5:124,348,536...124,403,117
Ensembl chr 5:124,348,461...124,403,195
JBrowse link
G C8b complement C8 beta chain decreases expression EXP nimesulide results in decreased expression of C8B mRNA CTD PMID:24136188 NCBI chr 5:124,298,269...124,338,055
Ensembl chr 5:124,300,477...124,338,053
JBrowse link
G C9 complement C9 decreases expression EXP nimesulide results in decreased expression of C9 mRNA CTD PMID:24136188 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP nimesulide results in decreased expression of CAR3 mRNA CTD PMID:24136188 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca8 carbonic anhydrase 8 increases expression EXP nimesulide results in increased expression of CAR8 mRNA CTD PMID:24136188 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Cacybp calcyclin binding protein increases expression EXP nimesulide results in increased expression of CACYBP mRNA CTD PMID:24136188 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Calm2 calmodulin 2 decreases expression EXP nimesulide results in decreased expression of CALM2 mRNA CTD PMID:24136188 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Canx calnexin increases expression EXP nimesulide results in increased expression of CANX mRNA CTD PMID:24136188 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 decreases expression EXP nimesulide results in decreased expression of CAP1 mRNA CTD PMID:24136188 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capn2 calpain 2 decreases expression EXP nimesulide results in decreased expression of CAPN2 mRNA CTD PMID:24136188 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP nimesulide results in decreased expression of CARHSP1 mRNA CTD PMID:24136188 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP3 protein
nimesulide results in increased cleavage of CASP3 protein
nimesulide results in increased expression of CASP3 mRNA
nimesulide results in increased activity of CASP3 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]
nimesulide results in increased expression of CASP3 mRNA; nimesulide results in increased expression of CASP3 protein
CTD PMID:11296547 PMID:19360361 PMID:19772912 PMID:21176579 PMID:21745461 PMID:22509279 PMID:24136188 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:19360361 PMID:21745461 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
ISO
EXP
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP9 protein
nimesulide results in increased cleavage of CASP9 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]
nimesulide results in increased activity of CASP9 protein
CTD PMID:19360361 PMID:19772912 PMID:21745461 PMID:22509279 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
ISO
EXP
nimesulide results in decreased expression of CAT protein
nimesulide results in decreased activity of CAT; nimesulide results in decreased activity of CAT protein
nimesulide inhibits the reaction [Quinolinic Acid results in decreased expression of CAT protein]
CTD PMID:17147060 PMID:17274466 PMID:18848576 PMID:20043943 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 increases expression ISO nimesulide results in increased expression of CAV1 protein CTD PMID:18848576 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP nimesulide results in increased expression of CAVIN3 mRNA CTD PMID:24136188 NCBI chr 1:170,317,099...170,318,688
Ensembl chr 1:170,317,113...170,318,935
JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP nimesulide results in increased expression of CBR1 mRNA CTD PMID:24136188 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Ccdc107 coiled-coil domain containing 107 decreases expression EXP nimesulide results in decreased expression of CCDC107 mRNA CTD PMID:24136188 NCBI chr 5:58,995,211...58,998,620
Ensembl chr 5:58,995,249...58,997,953
JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases expression EXP nimesulide results in increased expression of CCDC6 mRNA CTD PMID:24136188 NCBI chr20:19,729,005...19,825,219
Ensembl chr20:19,732,894...19,825,150
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression EXP nimesulide results in decreased expression of CCDC80 mRNA CTD PMID:24136188 NCBI chr11:60,645,660...60,679,249
Ensembl chr11:60,645,086...60,679,555
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
ISO
EXP
nimesulide results in decreased expression of CCL2 protein
[nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CCL2 mRNA
nimesulide inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; nimesulide inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein]
CTD PMID:17380299 PMID:20039930 PMID:22561872 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 decreases expression EXP nimesulide results in decreased expression of CCL6 mRNA CTD PMID:24136188 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO nimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein] CTD PMID:14966570 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP nimesulide results in decreased expression of CCNB2 mRNA CTD PMID:24136188 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA]
nimesulide results in decreased expression of CCND1 mRNA
CTD PMID:20043093 PMID:24136188 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression EXP nimesulide results in increased expression of CCT2 mRNA CTD PMID:24136188 NCBI chr 7:60,106,532...60,122,779
Ensembl chr 7:60,109,974...60,122,805
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP nimesulide results in increased expression of CCT3 mRNA CTD PMID:24136188 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression EXP nimesulide results in increased expression of CCT4 mRNA CTD PMID:24136188 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression EXP nimesulide results in increased expression of CCT5 mRNA CTD PMID:24136188 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression EXP nimesulide results in increased expression of CCT6A mRNA CTD PMID:24136188 NCBI chr12:30,491,584...30,501,813
Ensembl chr12:30,491,416...30,501,860
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression EXP nimesulide results in increased expression of CCT7 mRNA CTD PMID:24136188 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression EXP nimesulide results in increased expression of CCT8 mRNA CTD PMID:24136188 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd14 CD14 molecule decreases expression EXP nimesulide results in decreased expression of CD14 mRNA CTD PMID:24136188 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd164 CD164 molecule decreases expression EXP nimesulide results in decreased expression of CD164 mRNA CTD PMID:24136188 NCBI chr20:46,250,418...46,261,994
Ensembl chr20:46,250,363...46,261,994
JBrowse link
G Cd59 CD59 molecule decreases expression EXP nimesulide results in decreased expression of CD59 mRNA CTD PMID:24136188 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd5l Cd5 molecule-like decreases expression EXP nimesulide results in decreased expression of CD5L mRNA CTD PMID:24136188 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd68 Cd68 molecule decreases expression EXP nimesulide results in decreased expression of CD68 mRNA CTD PMID:24136188 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd74 CD74 molecule decreases expression EXP nimesulide results in decreased expression of CD74 mRNA CTD PMID:24136188 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd81 Cd81 molecule decreases expression EXP nimesulide results in decreased expression of CD81 mRNA CTD PMID:24136188 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cd82 Cd82 molecule decreases expression EXP nimesulide results in decreased expression of CD82 mRNA CTD PMID:24136188 NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP nimesulide results in decreased expression of CDC20 mRNA CTD PMID:24136188 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc5l cell division cycle 5-like decreases expression EXP nimesulide results in decreased expression of CDC5L mRNA CTD PMID:24136188 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cdh17 cadherin 17 increases expression EXP nimesulide results in increased expression of CDH17 mRNA CTD PMID:24136188 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdh2 cadherin 2 decreases expression EXP nimesulide results in decreased expression of CDH2 mRNA CTD PMID:24136188 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP nimesulide results in decreased expression of CDK1 mRNA CTD PMID:24136188 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO nimesulide results in increased expression of CDKN1A mRNA; nimesulide results in increased expression of CDKN1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased expression of CDKN1A mRNA]
CTD PMID:14567460 PMID:16376453 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO nimesulide results in increased expression of CDKN1B; nimesulide results in increased expression of CDKN1B protein CTD PMID:12717830 PMID:14567460 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO nimesulide inhibits the reaction [PTGS2 results in decreased expression of CDKN2C mRNA] CTD PMID:11961048 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP nimesulide results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP nimesulide results in decreased expression of CDO1 mRNA CTD PMID:24136188 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression EXP nimesulide results in decreased expression of CEACAM1 mRNA CTD PMID:24136188 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 decreases expression EXP nimesulide results in decreased expression of CEACAM10 mRNA CTD PMID:24136188 NCBI chr 1:81,643,809...81,650,085
Ensembl chr 1:81,643,816...81,650,094
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO
EXP
nimesulide promotes the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CEBPA protein]
nimesulide inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA]
CTD PMID:19247274 PMID:22107987 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cep170 centrosomal protein 170 decreases expression EXP nimesulide results in decreased expression of CEP170 mRNA CTD PMID:24136188 NCBI chr13:94,807,090...94,887,448
Ensembl chr13:94,807,756...94,859,436
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP nimesulide results in increased expression of CES2 mRNA CTD PMID:24136188 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfh complement factor H decreases expression EXP nimesulide results in decreased expression of CFH mRNA CTD PMID:24136188 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cfl1 cofilin 1 increases expression EXP nimesulide results in increased expression of CFL1 mRNA CTD PMID:24136188 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cgn cingulin decreases expression EXP nimesulide results in decreased expression of CGN mRNA CTD PMID:24136188 NCBI chr 2:195,909,691...195,937,130
Ensembl chr 2:195,909,626...195,935,878
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP nimesulide results in increased expression of CGRRF1 mRNA CTD PMID:24136188 NCBI chr15:23,619,176...23,639,622
Ensembl chr15:23,619,123...23,639,628
JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 increases expression EXP nimesulide results in increased expression of CHCHD1 mRNA CTD PMID:24136188 NCBI chr15:4,025,455...4,026,637
Ensembl chr15:4,025,463...4,026,637
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 increases expression EXP nimesulide results in increased expression of CHCHD2 mRNA CTD PMID:24136188 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP nimesulide results in increased expression of CHCHD6 mRNA CTD PMID:24136188 NCBI chr 4:121,340,952...121,565,222
Ensembl chr 4:121,340,952...121,565,212
JBrowse link
G Chid1 chitinase domain containing 1 increases expression EXP nimesulide results in increased expression of CHID1 mRNA CTD PMID:24136188 NCBI chr 1:214,476,418...214,511,569
Ensembl chr 1:214,476,387...214,511,529
JBrowse link
G Chka choline kinase alpha decreases expression EXP nimesulide results in decreased expression of CHKA mRNA CTD PMID:24136188 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression EXP nimesulide results in increased expression of CHORDC1 mRNA CTD PMID:24136188 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression EXP nimesulide results in increased expression of CHPT1 mRNA CTD PMID:24136188 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression EXP nimesulide results in increased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:114,323,542...114,326,930
Ensembl chr 7:114,323,542...114,326,930
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression EXP nimesulide results in increased expression of CHUK mRNA CTD PMID:24136188 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Churc1 churchill domain containing 1 increases expression EXP nimesulide results in increased expression of CHURC1 mRNA CTD PMID:24136188 NCBI chr 6:99,817,439...99,831,574
Ensembl chr 6:99,817,431...99,831,576
JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A increases expression EXP nimesulide results in increased expression of CIAO2A mRNA CTD PMID:24136188 NCBI chr 8:71,786,336...71,798,258
Ensembl chr 8:71,786,310...71,798,266
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression EXP nimesulide results in increased expression of CIAPIN1 mRNA CTD PMID:24136188 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP nimesulide results in increased expression of CIDEA mRNA CTD PMID:24136188 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP nimesulide results in increased expression of CISD2 mRNA CTD PMID:24136188 NCBI chr 2:240,586,754...240,611,560
Ensembl chr 2:240,586,754...240,611,560
JBrowse link
G Cisd3 CDGSH iron sulfur domain 3 increases expression EXP nimesulide results in increased expression of CISD3 mRNA CTD PMID:24136188 NCBI chr10:85,628,579...85,631,656
Ensembl chr10:85,628,491...85,631,657
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP nimesulide results in decreased expression of CITED2 mRNA CTD PMID:24136188 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression EXP nimesulide results in increased expression of CKS1B mRNA CTD PMID:24136188 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP nimesulide results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldnd1 claudin domain containing 1 increases expression EXP nimesulide results in increased expression of CLDND1 mRNA CTD PMID:24136188 NCBI chr11:43,986,352...43,992,703
Ensembl chr11:43,986,386...43,992,598
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP nimesulide results in decreased expression of CLEC4F mRNA CTD PMID:24136188 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression EXP nimesulide results in increased expression of CLIP1 mRNA CTD PMID:24136188 NCBI chr12:38,345,203...38,452,650
Ensembl chr12:38,345,456...38,452,652
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression EXP nimesulide results in increased expression of CLPP mRNA CTD PMID:24136188 NCBI chr 9:10,048,715...10,056,068
Ensembl chr 9:10,048,886...10,054,359
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression EXP nimesulide results in decreased expression of CLPX mRNA CTD PMID:24136188 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123
JBrowse link
G Cltb clathrin, light chain B increases expression EXP nimesulide results in increased expression of CLTB mRNA CTD PMID:24136188 NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression EXP nimesulide results in increased expression of CMBL mRNA CTD PMID:24136188 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 decreases expression EXP nimesulide results in decreased expression of CMTM6 mRNA CTD PMID:24136188 NCBI chr 8:122,789,208...122,807,560
Ensembl chr 8:122,789,453...122,807,560
JBrowse link
G Cndp2 carnosine dipeptidase 2 increases expression EXP nimesulide results in increased expression of CNDP2 mRNA CTD PMID:24136188 NCBI chr18:81,521,966...81,539,065
Ensembl chr18:81,521,968...81,539,065
JBrowse link
G Cnih4 cornichon family AMPA receptor auxiliary protein 4 increases expression EXP nimesulide results in increased expression of CNIH4 mRNA CTD PMID:24136188 NCBI chr13:99,469,382...99,490,693
Ensembl chr13:99,473,044...99,489,263
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide CTD PMID:20590570 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL14A1 mRNA CTD PMID:24136188 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL18A1 mRNA CTD PMID:24136188 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP nimesulide results in decreased expression of COL1A2 mRNA CTD PMID:24136188 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL3A1 mRNA CTD PMID:24136188 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL6A1 mRNA CTD PMID:24136188 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP nimesulide results in increased expression of COMMD5 mRNA CTD PMID:24136188 NCBI chr 7:117,963,213...117,965,010
Ensembl chr 7:118,502,676...118,504,097
Ensembl chr 7:118,502,676...118,504,097
JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 increases expression EXP nimesulide results in increased expression of COMTD1 mRNA CTD PMID:24136188 NCBI chr15:2,631,529...2,634,640
Ensembl chr15:2,631,529...2,634,640
JBrowse link
G Cops5 COP9 signalosome subunit 5 increases expression EXP nimesulide results in increased expression of COPS5 mRNA CTD PMID:24136188 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339
JBrowse link
G Coq10a coenzyme Q10A decreases expression EXP nimesulide results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr 7:2,780,930...2,788,189
Ensembl chr 7:2,780,930...2,786,949
JBrowse link
G Coq10b coenzyme Q10B increases expression EXP nimesulide results in increased expression of COQ10B mRNA CTD PMID:24136188 NCBI chr 9:61,655,963...61,675,880
Ensembl chr 9:61,655,963...61,675,873
JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression EXP nimesulide results in increased expression of COQ6 mRNA CTD PMID:24136188 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696
JBrowse link
G Coq8a coenzyme Q8A decreases expression EXP nimesulide results in decreased expression of COQ8A mRNA CTD PMID:24136188 NCBI chr13:98,451,629...98,480,438
Ensembl chr13:98,451,637...98,480,419
JBrowse link
G Coro1c coronin 1C decreases expression EXP nimesulide results in decreased expression of CORO1C mRNA CTD PMID:24136188 NCBI chr12:48,481,741...48,554,054
Ensembl chr12:48,481,750...48,554,052
JBrowse link
G Cox14 cytochrome c oxidase assembly factor COX14 increases expression EXP nimesulide results in increased expression of COX14 mRNA CTD PMID:24136188 NCBI chr 7:141,378,537...141,380,960
Ensembl chr 7:141,380,322...141,380,495
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression EXP nimesulide results in increased expression of COX17 mRNA CTD PMID:24136188 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cox19 cytochrome c oxidase assembly factor COX19 increases expression EXP nimesulide results in increased expression of COX19 mRNA CTD PMID:24136188 NCBI chr12:17,395,624...17,405,103
Ensembl chr12:17,395,624...17,405,103
JBrowse link
G Cp ceruloplasmin decreases expression EXP nimesulide results in decreased expression of CP mRNA CTD PMID:24136188 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP nimesulide results in decreased expression of PGCP mRNA CTD PMID:24136188 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP nimesulide results in decreased expression of CPS1 mRNA CTD PMID:24136188 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP nimesulide results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP nimesulide results in increased expression of CPT2 mRNA CTD PMID:24136188 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP nimesulide results in increased expression of CRAT mRNA CTD PMID:24136188 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP nimesulide results in increased expression of CREG1 mRNA CTD PMID:24136188 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675
JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 increases expression EXP nimesulide results in increased expression of CRELD1 mRNA CTD PMID:24136188 NCBI chr 4:145,440,284...145,449,894
Ensembl chr 4:145,440,114...145,449,892
JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP nimesulide results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression EXP nimesulide results in decreased expression of CROT mRNA CTD PMID:24136188 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP nimesulide results in increased expression of CRYL1 mRNA CTD PMID:24136188 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP nimesulide results in decreased expression of CSAD mRNA CTD PMID:24136188 NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP nimesulide results in decreased expression of CSF1R mRNA CTD PMID:24136188 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP nimesulide results in decreased expression of CSRP1 mRNA CTD PMID:24136188 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP nimesulide results in decreased expression of CTH mRNA CTD PMID:24136188 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 affects localization
decreases expression
ISO nimesulide affects the localization of CTNNB1 protein
nimesulide results in decreased expression of CTNNB1
CTD PMID:15892897 PMID:16331303 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsh cathepsin H decreases expression EXP nimesulide results in decreased expression of CTSH mRNA CTD PMID:24136188 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctsl cathepsin L increases expression EXP nimesulide results in increased expression of CTSL mRNA CTD PMID:24136188 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Ctss cathepsin S decreases expression EXP nimesulide results in decreased expression of CTSS mRNA CTD PMID:24136188 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL10 mRNA CTD PMID:22561872 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL11 mRNA CTD PMID:22561872 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP nimesulide results in decreased expression of CXCL12 mRNA CTD PMID:24136188 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL9 mRNA CTD PMID:22561872 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression EXP nimesulide results in decreased expression of CXXC5 mRNA CTD PMID:24136188 NCBI chr18:28,626,386...28,656,916
Ensembl chr18:28,653,592...28,656,937
JBrowse link
G Cyb5a cytochrome b5 type A increases expression EXP nimesulide results in increased expression of CYB5A mRNA CTD PMID:24136188 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyb5b cytochrome b5 type B increases expression EXP nimesulide results in increased expression of CYB5B mRNA CTD PMID:24136188 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189
JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression EXP nimesulide results in decreased expression of CYBB mRNA CTD PMID:24136188 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression
multiple interactions
ISO
EXP
nimesulide analog results in decreased activity of CYP19A1 protein; nimesulide results in decreased activity of CYP19A1; nimesulide results in decreased activity of CYP19A1 protein
nimesulide analog results in decreased expression of CYP19A1 mRNA; nimesulide results in decreased expression of CYP19A1 mRNA
nimesulide analog results in decreased activity of and results in decreased expression of CYP19A1
CTD PMID:15964185 PMID:17315855 PMID:20542113 PMID:23054057 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases glutathionylation
decreases expression
ISO
EXP
CYP1A2 protein results in increased glutathionylation of nimesulide
nimesulide results in decreased expression of CYP1A2 mRNA
CTD PMID:24136188 PMID:26524229 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases glutathionylation ISO CYP1B1 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 increases expression EXP nimesulide results in increased expression of CYP20A1 mRNA CTD PMID:24136188 NCBI chr 9:67,130,222...67,179,693
Ensembl chr 9:67,130,259...67,179,692
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP27A1 mRNA CTD PMID:24136188 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP2A1 mRNA CTD PMID:24136188 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP nimesulide results in decreased expression of CYP2A2 mRNA CTD PMID:24136188 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 increases expression EXP nimesulide results in increased expression of CYP2B12 mRNA CTD PMID:24136188 NCBI chr 1:83,511,167...83,522,965
Ensembl chr 1:83,511,167...83,584,589
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases glutathionylation
decreases expression
ISO
EXP
CYP2B6 protein results in increased glutathionylation of nimesulide
nimesulide results in decreased expression of CYP2B3 mRNA
CTD PMID:24136188 PMID:26524229 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases glutathionylation ISO CYP2C19 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases glutathionylation ISO CYP2D6 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 increases expression EXP nimesulide results in increased expression of CYP2J3 mRNA CTD PMID:24136188 NCBI chr 5:115,196,982...115,222,084 JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP2T1 mRNA CTD PMID:24136188 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein] CTD PMID:18079364 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP nimesulide results in increased expression of CYP3A9 mRNA CTD PMID:24136188 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP nimesulide results in increased expression of CYP4A1 mRNA CTD PMID:24136188 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP nimesulide results in increased expression of CYP4A3 mRNA CTD PMID:24136188 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP4F1 mRNA CTD PMID:24136188 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression EXP nimesulide results in decreased expression of CYP4F6 mRNA CTD PMID:24136188 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression EXP nimesulide results in decreased expression of DAAM1 mRNA CTD PMID:24136188 NCBI chr 6:94,606,675...94,739,026
Ensembl chr 6:94,636,222...94,739,026
JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP nimesulide results in decreased expression of DAG1 mRNA CTD PMID:24136188 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP nimesulide results in decreased expression of DAPK1 mRNA CTD PMID:24136188 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dazap1 DAZ associated protein 1 increases expression EXP nimesulide results in increased expression of DAZAP1 mRNA CTD PMID:24136188 NCBI chr 7:12,289,895...12,315,897
Ensembl chr 7:12,290,402...12,311,149
JBrowse link
G Ddc dopa decarboxylase decreases expression EXP nimesulide results in decreased expression of DDC mRNA CTD PMID:24136188 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP nimesulide results in decreased expression of DDHD1 mRNA CTD PMID:24136188 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of DDIT3 protein]
nimesulide results in increased expression of DDIT3 mRNA
CTD PMID:22940226 PMID:24136188 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression EXP nimesulide results in increased expression of DDOST mRNA CTD PMID:24136188 NCBI chr 5:156,668,924...156,676,036
Ensembl chr 5:156,668,712...156,676,035
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression EXP nimesulide results in decreased expression of DDX17 mRNA CTD PMID:24136188 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression EXP nimesulide results in increased expression of DDX39A mRNA CTD PMID:24136188 NCBI chr19:24,846,530...24,854,886
Ensembl chr19:24,846,938...24,854,953
JBrowse link
G Ddx58 DEXD/H-box helicase 58 decreases expression EXP nimesulide results in decreased expression of DDX58 mRNA CTD PMID:24136188 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP nimesulide results in increased expression of DECR1 mRNA CTD PMID:24136188 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP nimesulide results in increased expression of DECR2 mRNA CTD PMID:24136188 NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
JBrowse link
G Derl1 derlin 1 increases expression EXP nimesulide results in increased expression of DERL1 mRNA CTD PMID:24136188 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852
JBrowse link
G Desi1 desumoylating isopeptidase 1 increases expression EXP nimesulide results in increased expression of DESI1 mRNA CTD PMID:24136188 NCBI chr 7:123,238,332...123,259,636
Ensembl chr 7:123,238,333...123,259,636
JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression EXP nimesulide results in increased expression of DESI2 mRNA CTD PMID:24136188 NCBI chr13:96,111,800...96,156,693
Ensembl chr13:96,111,800...96,154,685
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression EXP nimesulide results in decreased expression of DGAT2 mRNA CTD PMID:24136188 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit increases expression EXP nimesulide results in increased expression of DHDDS mRNA CTD PMID:24136188 NCBI chr 5:152,200,681...152,227,669
Ensembl chr 5:152,199,584...152,227,677
JBrowse link
G Dhfr dihydrofolate reductase decreases expression EXP nimesulide results in decreased expression of DHFR mRNA CTD PMID:24136188 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 increases expression EXP nimesulide results in increased expression of DHRS4 mRNA CTD PMID:24136188 NCBI chr15:34,155,043...34,167,073
Ensembl chr15:34,155,504...34,167,072
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression EXP nimesulide results in increased expression of DHRS7 mRNA CTD PMID:24136188 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B increases expression EXP nimesulide results in increased expression of DHRS7B mRNA CTD PMID:24136188 NCBI chr10:47,065,755...47,111,089
Ensembl chr10:47,065,850...47,111,101
JBrowse link
G Dmgdh dimethylglycine dehydrogenase decreases expression EXP nimesulide results in decreased expression of DMGDH mRNA CTD PMID:24136188 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression EXP nimesulide results in increased expression of DNAJA3 mRNA CTD PMID:24136188 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP nimesulide results in increased expression of DNAJB1 mRNA CTD PMID:24136188 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression EXP nimesulide results in increased expression of DNAJB11 mRNA CTD PMID:24136188 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP nimesulide results in increased expression of DNAJB9 mRNA CTD PMID:24136188 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression EXP nimesulide results in increased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Dnlz DNL-type zinc finger increases expression EXP nimesulide results in increased expression of DNLZ mRNA CTD PMID:24136188 NCBI chr 3:3,796,480...3,798,467
Ensembl chr 3:3,796,480...3,798,239
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 increases expression EXP nimesulide results in increased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dph3 diphthamide biosynthesis 3 increases expression EXP nimesulide results in increased expression of DPH3 mRNA CTD PMID:24136188 NCBI chr16:8,202,048...8,207,492
Ensembl chr16:8,202,048...8,207,464
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression EXP nimesulide results in increased expression of DPM3 mRNA CTD PMID:24136188 NCBI chr 2:188,583,664...188,584,179
Ensembl chr 2:188,583,664...188,584,179
JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit increases expression EXP nimesulide results in increased expression of DPY30 mRNA CTD PMID:24136188 NCBI chr 6:22,296,128...22,316,894
Ensembl chr 6:22,296,128...22,316,894
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP nimesulide results in decreased expression of DPYD mRNA CTD PMID:24136188 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dpys dihydropyrimidinase decreases expression EXP nimesulide results in decreased expression of DPYS mRNA CTD PMID:24136188 NCBI chr 7:78,769,918...78,847,941
Ensembl chr 7:78,769,807...78,847,974
JBrowse link
G Dsc2 desmocollin 2 increases expression EXP nimesulide results in increased expression of DSC2 mRNA CTD PMID:24136188 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754
JBrowse link
G Dtd1 D-aminoacyl-tRNA deacylase 1 increases expression EXP nimesulide results in increased expression of DTD1 mRNA CTD PMID:24136188 NCBI chr 3:138,770,573...138,931,544
Ensembl chr 3:138,770,574...138,931,549
JBrowse link
G Dusp11 dual specificity phosphatase 11 increases expression EXP nimesulide results in increased expression of DUSP11 mRNA CTD PMID:24136188 NCBI chr 4:117,617,640...117,631,674
Ensembl chr 4:117,617,533...117,631,716
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression EXP nimesulide results in decreased expression of DYNLT3 mRNA CTD PMID:24136188 NCBI chr  X:14,633,342...14,642,356
Ensembl chr  X:14,633,342...14,642,424
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression EXP nimesulide results in increased expression of EBNA1BP2 mRNA CTD PMID:24136188 NCBI chr 5:137,458,692...137,463,255
Ensembl chr 5:137,670,123...137,674,802
JBrowse link
G Ebpl EBP like increases expression EXP nimesulide results in increased expression of EBPL mRNA CTD PMID:24136188 NCBI chr15:41,668,119...41,691,518
Ensembl chr15:41,668,119...41,691,518
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP nimesulide results in increased expression of ECH1 mRNA CTD PMID:24136188 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP nimesulide results in increased expression of ECI1 mRNA CTD PMID:24136188 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold increases expression EXP nimesulide results in increased expression of ECPAS mRNA CTD PMID:24136188 NCBI chr 5:75,928,510...76,040,771
Ensembl chr 5:75,931,293...76,039,760
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 increases expression EXP nimesulide results in increased expression of EDEM2 mRNA CTD PMID:24136188 NCBI chr 3:151,232,741...151,258,559
Ensembl chr 3:151,232,751...151,258,580
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein] CTD PMID:21811393 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression EXP nimesulide results in increased expression of EEF1B2 mRNA CTD PMID:24136188 NCBI chr 9:69,953,440...69,956,158
Ensembl chr 9:69,953,440...69,956,160
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta increases expression EXP nimesulide results in increased expression of EEF1D mRNA CTD PMID:24136188 NCBI chr 7:116,928,264...116,942,981
Ensembl chr 7:116,928,265...116,936,674
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression EXP nimesulide results in increased expression of EEF1E1 mRNA CTD PMID:24136188 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161
JBrowse link
G Egf epidermal growth factor decreases expression EXP nimesulide results in decreased expression of EGF mRNA CTD PMID:24136188 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Ehbp1 EH domain binding protein 1 decreases expression EXP nimesulide results in decreased expression of EHBP1 mRNA CTD PMID:24136188 NCBI chr14:106,871,426...107,160,224
Ensembl chr14:106,871,430...107,160,334
JBrowse link
G Ehd3 EH-domain containing 3 decreases expression EXP nimesulide results in decreased expression of EHD3 mRNA CTD PMID:24136188 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 decreases expression EXP nimesulide results in decreased expression of EIF2AK1 mRNA CTD PMID:24136188 NCBI chr12:12,749,026...12,782,078
Ensembl chr12:12,748,785...12,782,146
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression EXP nimesulide results in increased expression of EIF2S1 mRNA CTD PMID:24136188 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B increases expression EXP nimesulide results in increased expression of EIF3B mRNA CTD PMID:24136188 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I increases expression EXP nimesulide results in increased expression of EIF3I mRNA CTD PMID:24136188 NCBI chr 5:147,796,580...147,803,853
Ensembl chr 5:147,796,662...147,803,851
JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M increases expression EXP nimesulide results in increased expression of EIF3M mRNA CTD PMID:24136188 NCBI chr 3:94,990,086...95,007,690
Ensembl chr 3:94,990,068...95,007,712
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression EXP nimesulide results in increased expression of EIF4A1 mRNA CTD PMID:24136188 NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP nimesulide results in increased expression of EIF4EBP1 mRNA CTD PMID:24136188 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 increases expression EXP nimesulide results in increased expression of EIF4G1 mRNA CTD PMID:24136188 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression EXP nimesulide results in increased expression of EIF5 mRNA CTD PMID:24136188 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP nimesulide results in increased expression of EIF5A mRNA CTD PMID:24136188 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eloc elongin C increases expression EXP nimesulide results in increased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:2,042,991...2,059,357
Ensembl chr 5:2,042,991...2,059,351
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression EXP nimesulide results in decreased expression of ELOVL5 mRNA CTD PMID:24136188 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP nimesulide results in decreased expression of ELOVL6 mRNA CTD PMID:24136188 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Emc10 ER membrane protein complex subunit 10 increases expression EXP nimesulide results in increased expression of EMC10 mRNA CTD PMID:24136188 NCBI chr 1:100,495,112...100,501,468
Ensembl chr 1:100,495,119...100,501,437
JBrowse link
G Emc6 ER membrane protein complex subunit 6 increases expression EXP nimesulide results in increased expression of EMC6 mRNA CTD PMID:24136188 NCBI chr10:59,741,772...59,743,338
Ensembl chr10:59,741,772...59,743,315
JBrowse link
G Emc7 ER membrane protein complex subunit 7 increases expression EXP nimesulide results in increased expression of EMC7 mRNA CTD PMID:24136188 NCBI chr 3:103,945,276...103,955,970
Ensembl chr 3:103,945,329...103,956,007
JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP nimesulide results in increased expression of EMC8 mRNA CTD PMID:24136188 NCBI chr19:54,235,949...54,245,810
Ensembl chr19:54,235,936...54,245,855
JBrowse link
G Eml4 EMAP like 4 decreases expression EXP nimesulide results in decreased expression of EML4 mRNA CTD PMID:24136188 NCBI chr 6:6,618,370...6,674,550
Ensembl chr 6:6,619,076...6,674,554
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP nimesulide results in increased expression of ENC1 mRNA CTD PMID:24136188 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Enpep glutamyl aminopeptidase decreases expression EXP nimesulide results in decreased expression of ENPEP mRNA CTD PMID:24136188 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression EXP nimesulide results in increased expression of ENPP2 mRNA CTD PMID:24136188 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP nimesulide results in increased expression of ENTPD5 mRNA CTD PMID:24136188 NCBI chr 6:108,087,677...108,123,811
Ensembl chr 6:108,087,418...108,120,579
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 increases expression EXP nimesulide results in increased expression of EPB41 mRNA CTD PMID:24136188 NCBI chr 5:150,081,727...150,243,186
Ensembl chr 5:150,084,611...150,167,077
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases glutathionylation
increases expression
ISO
EXP
EPHX1 protein results in decreased glutathionylation of nimesulide
nimesulide results in increased expression of EPHX1 mRNA
CTD PMID:24136188 PMID:26524229 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase increases expression EXP nimesulide results in increased expression of EPRS mRNA CTD PMID:24136188 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ereg epiregulin multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of EREG mRNA] CTD PMID:16888076 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression EXP nimesulide results in increased expression of ERP44 mRNA CTD PMID:24136188 NCBI chr 5:63,937,866...64,030,827
Ensembl chr 5:63,937,784...64,030,901
JBrowse link
G Esd esterase D increases expression EXP nimesulide results in increased expression of ESD mRNA CTD PMID:24136188 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Exosc4 exosome component 4 increases expression EXP nimesulide results in increased expression of EXOSC4 mRNA CTD PMID:24136188 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Exosc5 exosome component 5 increases expression EXP nimesulide results in increased expression of EXOSC5 mRNA CTD PMID:24136188 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression EXP nimesulide results in decreased expression of EXT1 mRNA CTD PMID:24136188 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G F10 coagulation factor X decreases expression EXP nimesulide results in decreased expression of F10 mRNA CTD PMID:24136188 NCBI chr16:81,803,169...81,822,476
Ensembl chr16:81,803,110...81,822,716
JBrowse link
G F2 coagulation factor II decreases activity
multiple interactions
ISO
EXP
nimesulide results in decreased activity of F2
nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [F2 protein affects the localization of PRKCE protein]
CTD PMID:17379757 PMID:21811393 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased expression of F3 mRNA] CTD PMID:25339356 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
decreases expression
ISO
EXP
[nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]
nimesulide results in decreased expression of FAAH mRNA
CTD PMID:20702753 PMID:24136188 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Faahl fatty-acid amide hydrolase-like multiple interactions ISO [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide] CTD PMID:20702753 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP nimesulide results in decreased expression of FABP5 mRNA CTD PMID:24136188 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP nimesulide results in decreased expression of FADS1 mRNA CTD PMID:24136188 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP nimesulide results in decreased expression of FADS2 mRNA CTD PMID:24136188 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam126b family with sequence similarity 126, member B increases expression EXP nimesulide results in increased expression of FAM126B mRNA CTD PMID:24136188 NCBI chr 9:65,406,136...65,478,399
Ensembl chr 9:65,406,138...65,442,257
JBrowse link
G Fam214a family with sequence similarity 214, member A decreases expression EXP nimesulide results in decreased expression of FAM214A mRNA CTD PMID:24136188 NCBI chr 8:81,863,619...81,941,548
Ensembl chr 8:81,863,619...81,941,536
JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A increases expression EXP nimesulide results in increased expression of FAM3A mRNA CTD PMID:24136188 NCBI chr  X:156,319,687...156,328,974
Ensembl chr  X:156,319,687...156,328,309
JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta increases expression EXP nimesulide results in increased expression of FARSB mRNA CTD PMID:24136188 NCBI chr 9:84,324,456...84,383,674
Ensembl chr 9:84,324,442...84,383,687
JBrowse link
G Fasn fatty acid synthase decreases expression EXP nimesulide results in decreased expression of FASN mRNA CTD PMID:24136188 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbl fibrillarin increases expression EXP nimesulide results in increased expression of FBL mRNA CTD PMID:24136188 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fbxo31 F-box protein 31 increases expression EXP nimesulide results in increased expression of FBXO31 mRNA CTD PMID:24136188 NCBI chr19:53,487,610...53,625,673
Ensembl chr19:53,487,613...53,625,673
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa decreases expression EXP nimesulide results in decreased expression of FCGR2A mRNA CTD PMID:24136188 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 decreases expression EXP nimesulide results in decreased expression of FCHSD2 mRNA CTD PMID:24136188 NCBI chr 1:166,140,025...166,395,915
Ensembl chr 1:166,125,474...166,395,915
JBrowse link
G Fcna ficolin A decreases expression EXP nimesulide results in decreased expression of FCNA mRNA CTD PMID:24136188 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fdx2 ferredoxin 2 increases expression EXP nimesulide results in increased expression of FDX2 mRNA CTD PMID:24136188 NCBI chr 8:22,086,534...22,091,450
Ensembl chr 8:22,086,534...22,091,450
JBrowse link
G Fech ferrochelatase increases expression EXP nimesulide results in increased expression of FECH mRNA CTD PMID:24136188 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP nimesulide results in decreased expression of FGA mRNA CTD PMID:24136188 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 increases expression EXP nimesulide results in increased expression of FITM2 mRNA CTD PMID:24136188 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP nimesulide results in increased expression of FKBP11 mRNA CTD PMID:24136188 NCBI chr 7:140,398,253...140,402,664
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 increases expression EXP nimesulide results in increased expression of FKBP3 mRNA CTD PMID:24136188 NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP nimesulide results in decreased expression of FMO1 mRNA CTD PMID:24136188 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fn1 fibronectin 1 decreases expression EXP nimesulide results in decreased expression of FN1 mRNA CTD PMID:24136188 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxn3 forkhead box N3 decreases expression EXP nimesulide results in decreased expression of FOXN3 mRNA CTD PMID:24136188 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695
JBrowse link
G Fpgs folylpolyglutamate synthase increases expression EXP nimesulide results in increased expression of FPGS mRNA CTD PMID:24136188 NCBI chr 3:11,717,667...11,729,694
Ensembl chr 3:11,717,667...11,723,327
JBrowse link
G Fstl1 follistatin-like 1 decreases expression EXP nimesulide results in decreased expression of FSTL1 mRNA CTD PMID:24136188 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase increases expression EXP nimesulide results in increased expression of FTCD mRNA CTD PMID:24136188 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP nimesulide results in increased expression of FTL1 mRNA CTD PMID:24136188 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fuca1 alpha-L-fucosidase 1 decreases expression EXP nimesulide results in decreased expression of FUCA1 mRNA CTD PMID:24136188 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G Fxn frataxin increases expression EXP nimesulide results in increased expression of FXN mRNA CTD PMID:24136188 NCBI chr 1:242,123,975...242,152,834
Ensembl chr 1:242,123,975...242,152,834
JBrowse link
G Fzd8 frizzled class receptor 8 decreases expression EXP nimesulide results in decreased expression of FZD8 mRNA CTD PMID:24136188 NCBI chr17:62,259,910...62,267,239
Ensembl chr17:62,262,129...62,265,113
JBrowse link
G Gaa glucosidase, alpha, acid increases expression EXP nimesulide results in increased expression of GAA mRNA CTD PMID:24136188 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP nimesulide results in increased expression of GADD45A mRNA CTD PMID:24136188 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP nimesulide results in decreased expression of GADD45G mRNA CTD PMID:24136188 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Galk1 galactokinase 1 increases expression EXP nimesulide results in increased expression of GALK1 mRNA CTD PMID:24136188 NCBI chr10:104,560,322...104,564,499
Ensembl chr10:104,560,303...104,564,480
JBrowse link
G Galm galactose mutarotase decreases expression EXP nimesulide results in decreased expression of GALM mRNA CTD PMID:24136188 NCBI chr 6:2,808,988...2,860,742
Ensembl chr 6:2,808,841...2,860,744
JBrowse link
G Gas6 growth arrest specific 6 decreases expression EXP nimesulide results in decreased expression of GAS6 mRNA CTD PMID:24136188 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gata6 GATA binding protein 6 decreases expression EXP nimesulide results in decreased expression of GATA6 mRNA CTD PMID:24136188 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP nimesulide results in decreased expression of GC mRNA CTD PMID:24136188 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gcat glycine C-acetyltransferase decreases expression EXP nimesulide results in decreased expression of GCAT mRNA CTD PMID:24136188 NCBI chr 7:120,263,068...120,269,365
Ensembl chr 7:120,263,054...120,269,451
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP nimesulide results in increased expression of GCH1 mRNA CTD PMID:24136188 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gckr glucokinase regulator decreases expression EXP nimesulide results in decreased expression of GCKR mRNA CTD PMID:24136188 NCBI chr 6:26,355,296...26,385,761
Ensembl chr 6:26,355,296...26,385,761
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP nimesulide results in increased expression of GCLC mRNA CTD PMID:24136188 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP nimesulide results in increased expression of GCLM mRNA CTD PMID:24136188 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gda guanine deaminase increases expression EXP nimesulide results in increased expression of GDA mRNA CTD PMID:24136188 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 increases expression EXP nimesulide results in increased expression of GDE1 mRNA CTD PMID:24136188 NCBI chr 1:188,367,550...188,407,125
Ensembl chr 1:188,394,814...188,407,132
JBrowse link
G Ggct gamma-glutamyl cyclotransferase increases expression EXP nimesulide results in increased expression of GGCT mRNA CTD PMID:24136188 NCBI chr 4:85,186,644...85,192,857
Ensembl chr 4:85,186,644...85,192,834
JBrowse link
G Ggh gamma-glutamyl hydrolase increases expression EXP nimesulide results in increased expression of GGH mRNA CTD PMID:24136188 NCBI chr 5:34,040,258...34,063,369
Ensembl chr 5:34,040,258...34,063,361
JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression EXP nimesulide results in increased expression of GHITM mRNA CTD PMID:24136188 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Ghr growth hormone receptor decreases expression EXP nimesulide results in decreased expression of GHR mRNA CTD PMID:24136188 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gk glycerol kinase decreases expression EXP nimesulide results in decreased expression of GK mRNA CTD PMID:24136188 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gldc glycine decarboxylase decreases expression EXP nimesulide results in decreased expression of GLDC mRNA CTD PMID:24136188 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G Glrx2 glutaredoxin 2 increases expression EXP nimesulide results in increased expression of GLRX2 mRNA CTD PMID:24136188 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916
JBrowse link
G Gls2 glutaminase 2 decreases expression EXP nimesulide results in decreased expression of GLS2 mRNA CTD PMID:24136188 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP nimesulide results in decreased expression of GLUD1 mRNA CTD PMID:24136188 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP nimesulide results in decreased expression of GLUL mRNA CTD PMID:24136188 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP nimesulide results in increased expression of GLYAT mRNA CTD PMID:24136188 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Gm2a GM2 ganglioside activator decreases expression EXP nimesulide results in decreased expression of GM2A mRNA CTD PMID:24136188 NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930
JBrowse link
G Gmppa GDP-mannose pyrophosphorylase A increases expression EXP nimesulide results in increased expression of GMPPA mRNA CTD PMID:24136188 NCBI chr 9:82,632,267...82,639,811
Ensembl chr 9:82,632,230...82,639,821
JBrowse link
G Gmpr2 guanosine monophosphate reductase 2 increases expression EXP nimesulide results in increased expression of GMPR2 mRNA CTD PMID:24136188 NCBI chr15:34,352,857...34,362,074
Ensembl chr15:34,352,914...34,362,032
JBrowse link
G Gmps guanine monophosphate synthase increases expression EXP nimesulide results in increased expression of GMPS mRNA CTD PMID:24136188 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662
JBrowse link
G Gnas GNAS complex locus decreases expression EXP nimesulide results in decreased expression of GNAS mRNA CTD PMID:24136188 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression EXP nimesulide results in decreased expression of GNE mRNA CTD PMID:24136188 NCBI chr 5:59,511,738...59,553,421
Ensembl chr 5:59,512,872...59,553,416
JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP nimesulide results in increased expression of GNL3 mRNA CTD PMID:24136188 NCBI chr16:7,097,580...7,103,518
Ensembl chr16:7,097,507...7,103,604
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP nimesulide results in decreased expression of GNMT mRNA CTD PMID:24136188 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase decreases expression EXP nimesulide results in decreased expression of GNS mRNA CTD PMID:24136188 NCBI chr 7:63,467,027...63,501,054
Ensembl chr 7:63,467,216...63,499,353
JBrowse link
G Golt1a golgi transport 1A increases expression EXP nimesulide results in increased expression of GOLT1A mRNA CTD PMID:24136188 NCBI chr13:50,532,116...50,550,029
Ensembl chr13:50,537,133...50,550,015
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP nimesulide results in decreased expression of GPAM mRNA CTD PMID:24136188 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 increases expression EXP nimesulide results in increased expression of GPAT4 mRNA CTD PMID:24136188 NCBI chr16:73,615,949...73,649,769
Ensembl chr16:73,615,949...73,649,767
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression EXP nimesulide results in decreased expression of GPLD1 mRNA CTD PMID:24136188 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP nimesulide results in increased expression of GPT mRNA CTD PMID:24136188 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression EXP nimesulide results in decreased expression of GPT2 mRNA CTD PMID:24136188 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions
ISO
EXP
nimesulide results in decreased expression of GPX1 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA]; Silymarin inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA]
CTD PMID:18848576 PMID:22509279 PMID:24136188 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grn granulin precursor decreases expression EXP nimesulide results in decreased expression of GRN mRNA CTD PMID:24136188 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity ISO nimesulide results in decreased activity of GSK3B protein CTD PMID:16331303 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
decreases activity
decreases expression
multiple interactions
EXP nimesulide results in increased expression of GSR mRNA
nimesulide results in decreased activity of GSR protein
nimesulide results in decreased expression of GSR mRNA
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; Silymarin inhibits the reaction [nimesulide results in decreased activity of GSR protein]; Silymarin inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]
CTD PMID:22509279 PMID:24136188 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression EXP nimesulide results in increased expression of GSS mRNA CTD PMID:24136188 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP nimesulide results in increased expression of GSTA2 mRNA CTD PMID:24136188 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP nimesulide results in increased expression of GSTA3 mRNA CTD PMID:24136188 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP nimesulide results in increased expression of GSTA4 mRNA CTD PMID:24136188 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP nimesulide results in increased expression of GSTM1 mRNA CTD PMID:24136188 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression EXP nimesulide results in increased expression of GSTM4 mRNA CTD PMID:24136188 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP nimesulide results in increased expression of GSTP1 mRNA CTD PMID:24136188 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression EXP nimesulide results in decreased expression of GSTZ1 mRNA CTD PMID:24136188 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression EXP nimesulide results in increased expression of GTF2H1 mRNA CTD PMID:24136188 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gtf3a general transcription factor III A increases expression EXP nimesulide results in increased expression of GTF3A mRNA CTD PMID:24136188 NCBI chr12:9,856,841...9,864,791
Ensembl chr12:9,856,842...9,864,791
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression EXP nimesulide results in decreased expression of GUCY1A1 mRNA CTD PMID:24136188 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Guk1 guanylate kinase 1 increases expression EXP nimesulide results in increased expression of GUK1 mRNA CTD PMID:24136188 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897
JBrowse link
G H1f0 H1 histone family, member 0 decreases expression EXP nimesulide results in decreased expression of H1F0 mRNA CTD PMID:24136188 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP nimesulide results in increased expression of HACL1 mRNA CTD PMID:24136188 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP nimesulide results in increased expression of HADHB mRNA CTD PMID:24136188 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Hal histidine ammonia lyase decreases expression EXP nimesulide results in decreased expression of HAL mRNA CTD PMID:24136188 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP nimesulide results in decreased expression of HAO1 mRNA CTD PMID:24136188 NCBI chr 3:127,444,900...127,500,709
Ensembl chr 3:127,444,902...127,500,709
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression EXP nimesulide results in increased expression of HARS mRNA CTD PMID:24136188 NCBI chr18:29,611,545...29,629,087
Ensembl chr18:29,611,547...29,629,087
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 decreases expression EXP nimesulide results in decreased expression of HBA-A1 mRNA CTD PMID:24136188 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP nimesulide results in decreased expression of HBA1 mRNA CTD PMID:24136188 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression EXP nimesulide results in decreased expression of HDAC2 mRNA CTD PMID:24136188 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdgf heparin binding growth factor increases expression EXP nimesulide results in increased expression of HDGF mRNA CTD PMID:24136188 NCBI chr 2:187,274,898...187,284,670
Ensembl chr 2:187,275,120...187,284,281
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression EXP nimesulide results in increased expression of HERPUD1 mRNA CTD PMID:24136188 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP nimesulide results in decreased expression of HES6 mRNA CTD PMID:24136188 NCBI chr 9:98,549,698...98,551,438
Ensembl chr 9:98,549,705...98,551,438
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP nimesulide results in decreased expression of HHEX mRNA CTD PMID:24136188 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases expression EXP nimesulide results in increased expression of HIBCH mRNA CTD PMID:24136188 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP nimesulide results in increased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Higd2a HIG1 hypoxia inducible domain family, member 2A increases expression EXP nimesulide results in increased expression of HIGD2A mRNA CTD PMID:24136188 NCBI chr17:10,558,714...10,559,638
Ensembl chr17:10,558,714...10,559,627
JBrowse link
G Hikeshi heat shock protein nuclear import factor increases expression EXP nimesulide results in increased expression of HIKESHI mRNA CTD PMID:24136188 NCBI chr 1:154,147,098...154,170,429
Ensembl chr 1:154,142,836...154,170,409
JBrowse link
G Hint2 histidine triad nucleotide binding protein 2 increases expression EXP nimesulide results in increased expression of HINT2 mRNA CTD PMID:24136188 NCBI chr 5:59,150,344...59,152,599
Ensembl chr 5:59,150,345...59,152,599
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B decreases expression EXP nimesulide results in decreased expression of HIST1H4B mRNA CTD PMID:24136188 NCBI chr17:44,522,144...44,526,587
Ensembl chr17:44,522,140...44,526,583
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP nimesulide results in decreased expression of HMGB2 mRNA CTD PMID:24136188 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP nimesulide results in increased expression of HMGCR mRNA CTD PMID:24136188 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 increases expression EXP nimesulide results in increased expression of HMGN1 mRNA CTD PMID:24136188 NCBI chr11:36,474,028...36,479,947
Ensembl chr11:36,474,840...36,479,868
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP nimesulide results in increased expression of HMOX1 mRNA CTD PMID:24136188 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 decreases expression EXP nimesulide results in decreased expression of HOGA1 mRNA CTD PMID:24136188 NCBI chr 1:261,291,742...261,319,743
Ensembl chr 1:261,291,870...261,318,984
JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression EXP nimesulide results in decreased expression of HOOK3 mRNA CTD PMID:24136188 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP nimesulide results in increased expression of HPRT1 mRNA CTD PMID:24136188 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA]; nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of PTGS2 mRNA] CTD PMID:20043093 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression EXP nimesulide results in increased expression of HSD17B12 mRNA CTD PMID:24136188 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression EXP nimesulide results in decreased expression of HSD17B13 mRNA CTD PMID:24136188 NCBI chr14:7,113,544...7,128,218
Ensembl chr14:7,113,544...7,128,218
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression EXP nimesulide results in increased expression of HSD17B4 mRNA CTD PMID:24136188 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression EXP nimesulide results in increased expression of HSDL2 mRNA CTD PMID:24136188 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP nimesulide results in increased expression of HSP90AA1 mRNA CTD PMID:24136188 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP nimesulide results in increased expression of HSP90AB1 mRNA CTD PMID:24136188 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression EXP nimesulide results in increased expression of HSPA13 mRNA CTD PMID:24136188 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP nimesulide results in increased expression of HSPA8 mRNA CTD PMID:24136188 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP nimesulide results in increased expression of HSPB1 mRNA CTD PMID:24136188 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression EXP nimesulide results in increased expression of HSPB8 mRNA CTD PMID:24136188 NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 increases expression EXP nimesulide results in increased expression of HSPBP1 mRNA CTD PMID:24136188 NCBI chr 1:72,732,418...72,756,087
Ensembl chr 1:72,732,668...72,756,082
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP nimesulide results in increased expression of HSPD1 mRNA CTD PMID:24136188 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP nimesulide results in increased expression of HSPE1 mRNA CTD PMID:24136188 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP nimesulide results in increased expression of HSPH1 mRNA CTD PMID:24136188 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP nimesulide results in increased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression EXP nimesulide results in decreased expression of HTRA1 mRNA CTD PMID:24136188 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Hyal3 hyaluronidase 3 decreases expression EXP nimesulide results in decreased expression of HYAL3 mRNA CTD PMID:24136188 NCBI chr 8:116,336,512...116,342,147
Ensembl chr 8:116,336,512...116,342,146
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP nimesulide results in increased expression of HYOU1 mRNA CTD PMID:24136188 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Iba57 iron-sulfur cluster assembly factor IBA57 increases expression EXP nimesulide results in increased expression of IBA57 mRNA CTD PMID:24136188 NCBI chr10:45,506,124...45,514,909
Ensembl chr10:45,504,504...45,514,878
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ketotifen co-treated with nimesulide] results in decreased expression of ICAM1 protein CTD PMID:12121561 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein decreases expression EXP nimesulide results in decreased expression of ID4 mRNA CTD PMID:24136188 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression EXP nimesulide results in decreased expression of IFIT2 mRNA CTD PMID:24136188 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression EXP nimesulide results in decreased expression of IFITM1 mRNA CTD PMID:24136188 NCBI chr 1:213,765,825...213,767,841
Ensembl chr 1:213,766,758...213,767,815
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IFNB1 mRNA CTD PMID:22561872 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
EXP
ISO
nimesulide inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Dinoprostone]
nimesulide results in decreased expression of IFNG
[nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IFNG mRNA
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide
CTD PMID:12911628 PMID:19362101 PMID:22561872 PMID:24136188 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression EXP nimesulide results in increased expression of IFRD1 mRNA CTD PMID:24136188 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 increases expression EXP nimesulide results in increased expression of IFRD2 mRNA CTD PMID:24136188 NCBI chr 8:116,343,096...116,348,318
Ensembl chr 8:116,343,096...116,348,314
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP nimesulide results in decreased expression of IGF1 mRNA CTD PMID:23142791 PMID:24136188 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP nimesulide results in decreased expression of IGFALS mRNA CTD PMID:24136188 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP nimesulide results in decreased expression of IGFBP3 mRNA CTD PMID:24136188 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP nimesulide results in decreased expression of IGFBP7 mRNA CTD PMID:24136188 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Lipopolysaccharides co-treated with nimesulide] results in decreased expression of IL10 CTD PMID:14984594 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide CTD PMID:19362101 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[Ketotifen co-treated with nimesulide] results in decreased expression of IL1B protein; nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB]; nimesulide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL1B protein]; nimesulide inhibits the reaction [Zymosan analog results in increased expression of IL1B protein]
nimesulide results in increased expression of IL1B
nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]
CTD PMID:12121561 PMID:12126971 PMID:12946449 PMID:22940226 PMID:24136188 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IL23A mRNA CTD PMID:22561872 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il4r interleukin 4 receptor decreases expression EXP nimesulide results in decreased expression of IL4RA mRNA CTD PMID:24136188 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
nimesulide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL6 protein]; nimesulide inhibits the reaction [Zymosan analog results in increased expression of IL6 protein]
nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of IL6 mRNA]
nimesulide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:12946449 PMID:19931610 PMID:22940226 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Imp3 IMP U3 small nucleolar ribonucleoprotein 3 increases expression EXP nimesulide results in increased expression of IMP3 mRNA CTD PMID:24136188 NCBI chr 8:61,607,021...61,607,909
Ensembl chr 8:61,607,015...61,608,457
JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression EXP nimesulide results in increased expression of IMP4 mRNA CTD PMID:24136188 NCBI chr 9:37,769,959...37,775,097
Ensembl chr 9:37,769,959...37,775,154
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression EXP nimesulide results in increased expression of IMPDH2 mRNA CTD PMID:24136188 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP nimesulide results in decreased expression of INHBA mRNA CTD PMID:24136188 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbc inhibin subunit beta C decreases expression EXP nimesulide results in decreased expression of INHBC mRNA CTD PMID:24136188 NCBI chr 7:70,648,005...70,661,475
Ensembl chr 7:70,646,519...70,661,891
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP nimesulide results in decreased expression of INHBE mRNA CTD PMID:24136188 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Ipo4 importin 4 increases expression EXP nimesulide results in increased expression of IPO4 mRNA CTD PMID:24136188 NCBI chr15:34,304,425...34,314,552
Ensembl chr15:34,304,425...34,314,345
JBrowse link
G Ipo5 importin 5 increases expression EXP nimesulide results in increased expression of IPO5 mRNA CTD PMID:24136188 NCBI chr15:106,243,110...106,293,326
Ensembl chr15:106,257,650...106,292,112
JBrowse link
G Ipo7 importin 7 increases expression EXP nimesulide results in increased expression of IPO7 mRNA CTD PMID:24136188 NCBI chr 1:174,655,939...174,696,173
Ensembl chr 1:174,655,939...174,696,173
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression EXP nimesulide results in increased expression of IRAK1 mRNA CTD PMID:24136188 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irf1 interferon regulatory factor 1 decreases expression EXP nimesulide results in decreased expression of IRF1 mRNA CTD PMID:24136188 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Irf6 interferon regulatory factor 6 decreases expression EXP nimesulide results in decreased expression of IRF6 mRNA CTD PMID:24136188 NCBI chr13:111,870,121...111,889,328
Ensembl chr13:111,870,121...111,889,328
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP nimesulide results in increased expression of ISYNA1 mRNA CTD PMID:24136188 NCBI chr16:20,589,497...20,592,333
Ensembl chr16:20,589,481...20,592,449
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 decreases expression EXP nimesulide results in decreased expression of ITIH1 mRNA CTD PMID:24136188 NCBI chr16:7,012,376...7,026,542
Ensembl chr16:7,012,354...7,026,540
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 decreases expression EXP nimesulide results in decreased expression of ITIH2 mRNA CTD PMID:24136188 NCBI chr17:72,160,734...72,197,248
Ensembl chr17:72,160,735...72,195,509
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP nimesulide results in decreased expression of IVD mRNA CTD PMID:24136188 NCBI chr 3:110,669,355...110,689,789
Ensembl chr 3:110,669,312...110,690,173
JBrowse link
G Iyd iodotyrosine deiodinase decreases expression EXP nimesulide results in decreased expression of IYD mRNA CTD PMID:24136188 NCBI chr 1:40,086,513...40,100,966
Ensembl chr 1:40,086,470...40,101,840
JBrowse link
G Jagn1 jagunal homolog 1 increases expression EXP nimesulide results in increased expression of JAGN1 mRNA CTD PMID:24136188 NCBI chr 4:145,399,885...145,404,605
Ensembl chr 4:145,399,913...145,404,617
JBrowse link
G Jak1 Janus kinase 1 decreases expression EXP nimesulide results in decreased expression of JAK1 mRNA CTD PMID:24136188 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression EXP nimesulide results in increased expression of JPT2 mRNA CTD PMID:24136188 NCBI chr10:14,304,108...14,324,170
Ensembl chr10:14,304,104...14,324,211
JBrowse link
G Jup junction plakoglobin decreases expression EXP nimesulide results in decreased expression of JUP mRNA CTD PMID:24136188 NCBI chr10:88,280,517...88,307,451
Ensembl chr10:88,279,632...88,307,412
JBrowse link
G Kcmf1 potassium channel modulatory factor 1 increases expression EXP nimesulide results in increased expression of KCMF1 mRNA CTD PMID:24136188 NCBI chr 4:100,759,526...100,783,017
Ensembl chr 4:100,759,526...100,783,750
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO nimesulide results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression EXP nimesulide results in increased expression of KCTD5 mRNA CTD PMID:24136188 NCBI chr10:13,420,152...13,446,323
Ensembl chr10:13,420,154...13,446,135
JBrowse link
G Khk ketohexokinase decreases expression EXP nimesulide results in decreased expression of KHK mRNA CTD PMID:24136188 NCBI chr 6:26,810,577...26,821,013
Ensembl chr 6:26,810,579...26,820,959
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of KLF4 mRNA] CTD PMID:25339356 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klkb1 kallikrein B1 increases response to substance
multiple interactions
ISO KLKB1 gene mutant form results in increased susceptibility to nimesulide
nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased expression of F3 mRNA]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased abundance of 6-Ketoprostaglandin F1 alpha]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of KLF4 mRNA]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of SIRT1 mRNA]
CTD PMID:25339356 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression EXP nimesulide results in decreased expression of KMO mRNA CTD PMID:24136188 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kng2 kininogen 2 multiple interactions
decreases expression
EXP nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [KNG1 protein affects the localization of PRKCE protein]
nimesulide results in decreased expression of KNG2 mRNA
CTD PMID:21811393 PMID:24136188 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt10 keratin 10 multiple interactions ISO [[GW0742 binds to and results in increased activity of PPARD protein] co-treated with [nimesulide results in decreased activity of PTGS2 protein]] results in increased expression of KRT10 mRNA CTD PMID:19748995 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt8 keratin 8 increases expression EXP nimesulide results in increased expression of KRT8 mRNA CTD PMID:24136188 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Kxd1 KxDL motif containing 1 increases expression EXP nimesulide results in increased expression of KXD1 mRNA CTD PMID:24136188 NCBI chr16:20,652,863...20,666,581
Ensembl chr16:20,657,099...20,666,579
JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases expression EXP nimesulide results in increased expression of KYAT1 mRNA CTD PMID:24136188 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Kynu kynureninase decreases expression EXP nimesulide results in decreased expression of KYNU mRNA CTD PMID:24136188 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases expression EXP nimesulide results in increased expression of LAMTOR1 mRNA CTD PMID:24136188 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 increases expression EXP nimesulide results in increased expression of LAMTOR2 mRNA CTD PMID:24136188 NCBI chr 2:187,911,530...187,914,930
Ensembl chr 2:187,911,533...187,915,596
JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP nimesulide results in increased expression of LAMTOR4 mRNA CTD PMID:24136188 NCBI chr12:19,573,909...19,577,625
Ensembl chr12:19,573,909...19,577,624
JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression EXP nimesulide results in decreased expression of LAP3 mRNA CTD PMID:24136188 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Laptm4a lysosomal protein transmembrane 4 alpha increases expression EXP nimesulide results in increased expression of LAPTM4A mRNA CTD PMID:24136188 NCBI chr 6:34,042,132...34,059,960
Ensembl chr 6:34,028,936...34,059,961
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta decreases expression EXP nimesulide results in decreased expression of LAPTM4B mRNA CTD PMID:24136188 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 decreases expression EXP nimesulide results in decreased expression of LCMT1 mRNA CTD PMID:24136188 NCBI chr 1:193,335,629...193,391,620
Ensembl chr 1:193,335,645...193,391,638
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 decreases expression EXP nimesulide results in decreased expression of LCP1 mRNA CTD PMID:24136188 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G Lct lactase affects activity
increases activity
multiple interactions
decreases activity
EXP nimesulide affects the activity of LCT protein
nimesulide results in increased activity of LCT; nimesulide results in increased activity of LCT protein
[nimesulide results in decreased activity of LCT protein] which results in decreased transport of Glucose
CTD PMID:16382204 PMID:16855794 PMID:17147060 PMID:18604318 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 decreases expression EXP nimesulide results in decreased expression of LECT2 mRNA CTD PMID:24136188 NCBI chr17:8,489,261...8,495,483
Ensembl chr17:8,489,266...8,495,496
JBrowse link
G Leprotl1 leptin receptor overlapping transcript-like 1 increases expression EXP nimesulide results in increased expression of LEPROTL1 mRNA CTD PMID:24136188 NCBI chr16:61,758,941...61,769,655
Ensembl chr16:61,758,917...61,771,569
JBrowse link
G Lgalsl galectin-like decreases expression EXP nimesulide results in decreased expression of LGALSL mRNA CTD PMID:24136188 NCBI chr14:105,047,915...105,055,421
Ensembl chr14:105,047,919...105,055,421
JBrowse link
G Lgmn legumain decreases expression EXP nimesulide results in decreased expression of LGMN mRNA CTD PMID:24136188 NCBI chr 6:126,282,246...126,308,207
Ensembl chr 6:126,282,233...126,320,726
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of AREG mRNA]; nimesulide inhibits the reaction [LHB results in increased expression of AREG protein]; nimesulide inhibits the reaction [LHB results in increased expression of EREG mRNA] CTD PMID:16888076 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase decreases expression EXP nimesulide results in decreased expression of LHPP mRNA CTD PMID:24136188 NCBI chr 1:204,617,804...204,708,987
Ensembl chr 1:204,617,852...204,708,987
JBrowse link
G Lipc lipase C, hepatic type decreases expression EXP nimesulide results in decreased expression of LIPC mRNA CTD PMID:24136188 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G LOC100360841 ribosomal protein L37-like increases expression EXP nimesulide results in increased expression of RPL37 mRNA CTD PMID:24136188 NCBI chr 9:69,790,829...69,791,199
Ensembl chr 9:69,790,831...69,791,196
JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression EXP nimesulide results in decreased expression of LRAT mRNA CTD PMID:24136188 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300
JBrowse link
G Lrp5 LDL receptor related protein 5 decreases expression EXP nimesulide results in decreased expression of LRP5 mRNA CTD PMID:24136188 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrrc28 leucine rich repeat containing 28 increases expression EXP nimesulide results in increased expression of LRRC28 mRNA CTD PMID:24136188 NCBI chr 1:128,486,164...128,604,190
Ensembl chr 1:128,486,166...128,604,188
JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression EXP nimesulide results in decreased expression of LTA4H mRNA CTD PMID:24136188 NCBI chr 7:34,288,333...34,320,243
Ensembl chr 7:34,288,365...34,320,235
JBrowse link
G Ltbr lymphotoxin beta receptor increases expression EXP nimesulide results in increased expression of LTBR mRNA CTD PMID:24136188 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Luc7l2 LUC7-like 2 pre-mRNA splicing factor decreases expression EXP nimesulide results in decreased expression of LUC7L2 mRNA CTD PMID:24136188 NCBI chr 4:66,290,319...66,357,970
Ensembl chr 4:66,290,389...66,354,711
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression EXP nimesulide results in decreased expression of LY6E mRNA CTD PMID:24136188 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression EXP nimesulide results in decreased expression of LYVE1 mRNA CTD PMID:24136188 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP nimesulide results in decreased expression of LYZ2 mRNA CTD PMID:24136188 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 decreases expression EXP nimesulide results in decreased expression of MACROD1 mRNA CTD PMID:24136188 NCBI chr 1:222,310,916...222,451,485
Ensembl chr 1:222,310,920...222,451,484
JBrowse link
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 increases expression EXP nimesulide results in increased expression of MAGMAS-PS1 mRNA CTD PMID:24136188 NCBI chr10:91,752,860...91,753,380 JBrowse link
G Magoh mago homolog, exon junction complex subunit increases expression EXP nimesulide results in increased expression of MAGOH mRNA CTD PMID:24136188 NCBI chr 5:127,480,465...127,487,617
Ensembl chr 5:127,480,485...127,487,603
JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 increases expression EXP nimesulide results in increased expression of MALSU1 mRNA CTD PMID:24136188 NCBI chr 4:78,735,279...78,744,102
Ensembl chr 4:78,735,279...78,744,102
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 decreases expression EXP nimesulide results in decreased expression of MAN2B1 mRNA CTD PMID:24136188 NCBI chr19:26,196,797...26,216,981
Ensembl chr19:26,196,837...26,216,267
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression EXP nimesulide results in increased expression of MANF mRNA CTD PMID:24136188 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression EXP nimesulide results in increased expression of MAP1LC3B mRNA CTD PMID:24136188 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression EXP nimesulide results in increased expression of MAP2K3 mRNA CTD PMID:24136188 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased phosphorylation of MAPK1 protein] CTD PMID:16376453 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased phosphorylation of MAPK3 protein] CTD PMID:16376453 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression EXP nimesulide results in decreased expression of MAPK9 mRNA CTD PMID:24136188 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 decreases expression EXP nimesulide results in decreased expression of MAPKAPK2 mRNA CTD PMID:24136188 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 increases expression EXP nimesulide results in increased expression of MARCHF5 mRNA CTD PMID:24136188 NCBI chr 1:255,842,642...255,864,131
Ensembl chr 1:255,842,783...255,863,142
JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 increases expression EXP nimesulide results in increased expression of MARCHF6 mRNA CTD PMID:24136188 NCBI chr 2:84,533,546...84,608,743
Ensembl chr 2:84,536,669...84,608,712
JBrowse link
G Marcksl1 MARCKS-like 1 decreases expression EXP nimesulide results in decreased expression of MARCKSL1 mRNA CTD PMID:24136188 NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
JBrowse link
G Masp1 mannan-binding lectin serine peptidase 1 decreases expression EXP nimesulide results in decreased expression of MASP1 mRNA CTD PMID:24136188 NCBI chr11:80,736,424...80,806,278
Ensembl chr11:80,736,576...80,803,382
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 increases expression EXP nimesulide results in increased expression of MBD3 mRNA CTD PMID:24136188 NCBI chr 7:12,179,046...12,186,251
Ensembl chr 7:12,179,203...12,186,656
JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression EXP nimesulide results in decreased expression of MBL2 mRNA CTD PMID:24136188 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mbtd1 mbt domain containing 1 decreases expression EXP nimesulide results in decreased expression of MBTD1 mRNA CTD PMID:24136188 NCBI chr10:81,588,233...81,645,532
Ensembl chr10:81,592,114...81,642,663
JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 decreases expression EXP nimesulide results in decreased expression of MCCC2 mRNA CTD PMID:24136188 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression EXP nimesulide results in increased expression of MCM4 mRNA CTD PMID:24136188 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP nimesulide results in increased expression of MCM6 mRNA CTD PMID:24136188 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 increases expression EXP nimesulide results in increased expression of MCM7 mRNA CTD PMID:24136188 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 increases expression EXP nimesulide results in increased expression of MCOLN1 mRNA CTD PMID:24136188 NCBI chr12:2,054,629...2,068,682
Ensembl chr12:2,054,680...2,068,682
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP nimesulide results in increased expression of MDM2 mRNA CTD PMID:24136188 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Med29 mediator complex subunit 29 increases expression EXP nimesulide results in increased expression of MED29 mRNA CTD PMID:24136188 NCBI chr 1:85,368,288...85,373,691
Ensembl chr 1:85,368,288...85,373,099
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression EXP nimesulide results in decreased expression of MFGE8 mRNA CTD PMID:24136188 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP nimesulide results in decreased expression of MGAT4B mRNA CTD PMID:24136188 NCBI chr10:35,726,501...35,736,338
Ensembl chr10:35,726,544...35,736,338
JBrowse link
G Mgll monoglyceride lipase increases expression EXP nimesulide results in increased expression of MGLL mRNA CTD PMID:24136188 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression EXP nimesulide results in increased expression of MGST2 mRNA CTD PMID:24136188 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 decreases expression EXP nimesulide results in decreased expression of MGST3 mRNA CTD PMID:24136188 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 increases expression EXP nimesulide results in increased expression of MIA3 mRNA CTD PMID:24136188 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541
JBrowse link
G Mid1ip1 MID1 interacting protein 1 decreases expression EXP nimesulide results in decreased expression of MID1IP1 mRNA CTD PMID:24136188 NCBI chr  X:13,114,557...13,119,274
Ensembl chr  X:13,114,569...13,116,743
JBrowse link
G Mix23 mitochondrial matrix import factor 23 increases expression EXP nimesulide results in increased expression of CCDC58 mRNA CTD PMID:24136188 NCBI chr11:67,598,419...67,618,704
Ensembl chr11:67,598,419...67,618,704
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP nimesulide inhibits the reaction [[Sulfadimethoxine co-treated with diisopropanolnitrosamine] results in increased expression of MKI67 protein] CTD PMID:22387750 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlec malectin increases expression EXP nimesulide results in increased expression of MLEC mRNA CTD PMID:24136188 NCBI chr12:47,219,071...47,233,769
Ensembl chr12:47,218,969...47,252,286
JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression EXP nimesulide results in increased expression of MLYCD mRNA CTD PMID:24136188 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753
JBrowse link
G Mmgt1 membrane magnesium transporter 1 increases expression EXP nimesulide results in increased expression of MMGT1 mRNA CTD PMID:24136188 NCBI chr  X:158,966,694...158,978,995
Ensembl chr  X:158,966,673...158,978,995
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO nimesulide results in decreased expression of MMP9 mRNA; nimesulide results in decreased expression of MMP9 protein CTD PMID:21176579 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 increases expression EXP nimesulide results in increased expression of MOCS2 mRNA CTD PMID:24136188 NCBI chr 2:46,980,964...46,992,886
Ensembl chr 2:46,980,976...46,992,883
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase increases expression EXP nimesulide results in increased expression of MOGS mRNA CTD PMID:24136188 NCBI chr 4:113,948,328...113,951,731
Ensembl chr 4:113,948,514...113,951,847
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 increases expression EXP nimesulide results in increased expression of MPC2 mRNA CTD PMID:24136188 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213
JBrowse link
G Mpo myeloperoxidase decreases activity
multiple interactions
EXP
ISO
nimesulide results in decreased activity of MPO
nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
[[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite
CTD PMID:11137876 PMID:11996850 PMID:20939553 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpp1 membrane palmitoylated protein 1 decreases expression EXP nimesulide results in decreased expression of MPP1 mRNA CTD PMID:24136188 NCBI chr 1:148,450,213...148,458,945 JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression EXP nimesulide results in decreased expression of MRC1 mRNA CTD PMID:24136188 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 increases expression EXP nimesulide results in increased expression of MRPL12 mRNA CTD PMID:24136188 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 increases expression EXP nimesulide results in increased expression of MRPL14 mRNA CTD PMID:24136188 NCBI chr 9:17,687,622...17,698,591
Ensembl chr 9:17,687,622...17,698,569
JBrowse link
G Mrpl17 mitochondrial ribosomal protein L17 increases expression EXP nimesulide results in increased expression of MRPL17 mRNA CTD PMID:24136188 NCBI chr 1:170,652,293...170,653,982
Ensembl chr 1:170,652,294...170,653,920
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 increases expression EXP nimesulide results in increased expression of MRPL18 mRNA CTD PMID:24136188 NCBI chr 1:48,033,531...48,038,726
Ensembl chr 1:48,033,768...48,038,726
JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 increases expression EXP nimesulide results in increased expression of MRPL19 mRNA CTD PMID:24136188 NCBI chr 4:112,703,041...112,707,270
Ensembl chr 4:112,703,041...112,707,270
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 increases expression EXP nimesulide results in increased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:173,248,245...173,252,775
Ensembl chr 5:173,248,245...173,252,775
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 increases expression EXP nimesulide results in increased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:43,601,786...43,612,119
Ensembl chr10:43,601,689...43,612,121
JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 increases expression EXP nimesulide results in increased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:215,701,544...215,709,313
Ensembl chr 1:215,701,544...215,709,313
JBrowse link
G mrpl24 mitochondrial ribosomal protein L24 increases expression EXP nimesulide results in increased expression of MRPL24 mRNA CTD PMID:24136188 NCBI chr 2:187,288,460...187,294,676
Ensembl chr 2:187,288,644...187,294,656
JBrowse link
G Mrpl34 mitochondrial ribosomal protein L34 increases expression EXP nimesulide results in increased expression of MRPL34 mRNA CTD PMID:24136188 NCBI chr16:19,874,034...19,874,769
Ensembl chr16:19,874,034...19,874,768
JBrowse link
G Mrpl38 mitochondrial ribosomal protein L38 increases expression EXP nimesulide results in increased expression of MRPL38 mRNA CTD PMID:24136188 NCBI chr10:104,682,372...104,691,357
Ensembl chr10:104,682,374...104,689,178
JBrowse link
G Mrpl49 mitochondrial ribosomal protein L49 increases expression EXP nimesulide results in increased expression of MRPL49 mRNA CTD PMID:24136188 NCBI chr 1:221,417,336...221,420,115
Ensembl chr 1:221,417,336...221,420,115
JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 increases expression EXP nimesulide results in increased expression of MRPL50 mRNA CTD PMID:24136188 NCBI chr 5:64,784,164...64,789,318
Ensembl chr 5:64,784,170...64,789,318
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 increases expression EXP nimesulide results in increased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 4:113,942,037...113,942,927
Ensembl chr 4:113,942,041...113,942,674
JBrowse link
G Mrpl55 mitochondrial ribosomal protein L55 increases expression EXP nimesulide results in increased expression of MRPL55 mRNA CTD PMID:24136188 NCBI chr10:45,552,794...45,555,943
Ensembl chr10:45,552,795...45,555,943
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 increases expression EXP nimesulide results in increased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr13:77,940,454...77,946,201
Ensembl chr13:77,940,454...77,946,201
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B increases expression EXP nimesulide results in increased expression of MRPS18B mRNA CTD PMID:24136188 NCBI chr20:3,344,870...3,350,929
Ensembl chr20:3,344,870...3,350,927
JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C increases expression EXP nimesulide results in increased expression of MRPS18C mRNA CTD PMID:24136188 NCBI chr14:10,440,691...10,446,909
Ensembl chr14:10,440,691...10,446,909
JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 increases expression EXP nimesulide results in increased expression of MRPS27 mRNA CTD PMID:24136188 NCBI chr 2:29,598,344...29,666,711
Ensembl chr 2:29,598,344...29,666,724
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 increases expression EXP nimesulide results in increased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:67,606,971...67,616,056
Ensembl chr 4:67,607,273...67,610,710
JBrowse link
G Mrps34 mitochondrial ribosomal protein S34 increases expression EXP nimesulide results in increased expression of MRPS34 mRNA CTD PMID:24136188 NCBI chr10:14,257,001...14,258,132
Ensembl chr10:14,257,001...14,258,132
JBrowse link
G Mrps35 mitochondrial ribosomal protein S35 increases expression EXP nimesulide results in increased expression of MRPS35 mRNA CTD PMID:24136188 NCBI chr 4:181,434,793...181,465,318
Ensembl chr 4:181,434,812...181,465,318
JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 increases expression EXP nimesulide results in increased expression of MRPS7 mRNA CTD PMID:24136188 NCBI chr10:104,155,805...104,158,840
Ensembl chr10:104,155,805...104,158,839
JBrowse link
G Mrto4 MRT4 homolog, ribosome maturation factor increases expression EXP nimesulide results in increased expression of MRTO4 mRNA CTD PMID:24136188 NCBI chr 5:157,814,142...157,820,889
Ensembl chr 5:157,815,361...157,820,889
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression EXP nimesulide results in decreased expression of MTARC1 mRNA CTD PMID:24136188 NCBI chr13:102,693,679...102,724,120
Ensembl chr13:102,698,546...102,721,218
JBrowse link
G Mtx1 Metaxin 1 increases expression EXP nimesulide results in increased expression of MTX1 mRNA CTD PMID:24136188 NCBI chr 2:188,522,605...188,528,747
Ensembl chr 2:188,521,785...188,528,195
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP nimesulide results in decreased expression of MUG1 mRNA CTD PMID:24136188 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Mydgf myeloid-derived growth factor increases expression EXP nimesulide results in increased expression of MYDGF mRNA CTD PMID:24136188 NCBI chr 9:10,885,521...10,892,744
Ensembl chr 9:10,885,560...10,892,405
JBrowse link
G Myh9 myosin, heavy chain 9 decreases expression EXP nimesulide results in decreased expression of MYH9 mRNA CTD PMID:24136188 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Myo1b myosin Ib decreases expression EXP nimesulide results in decreased expression of MYO1B mRNA CTD PMID:24136188 NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054
JBrowse link
G Myo1d myosin ID decreases expression EXP nimesulide results in decreased expression of MYO1D mRNA CTD PMID:24136188 NCBI chr10:67,866,939...68,142,864
Ensembl chr10:67,866,940...68,142,864
JBrowse link
G Myo1g myosin IG increases expression EXP nimesulide results in increased expression of MYO1G mRNA CTD PMID:24136188 NCBI chr14:86,781,243...86,796,393
Ensembl chr14:86,781,202...86,796,378
JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit increases expression EXP nimesulide results in increased expression of NAA20 mRNA CTD PMID:24136188 NCBI chr 3:140,106,723...140,125,047
Ensembl chr 3:140,106,766...140,125,220
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression EXP nimesulide results in increased expression of NAA38 mRNA CTD PMID:24136188 NCBI chr10:55,997,614...55,998,691
Ensembl chr10:55,997,614...55,998,691
JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit increases expression EXP nimesulide results in increased expression of NAA50 mRNA CTD PMID:24136188 NCBI chr11:61,508,162...61,530,830
Ensembl chr11:61,462,994...61,530,837
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP nimesulide results in increased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP nimesulide results in increased expression of NAP1L1 mRNA CTD PMID:24136188 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nat8 N-acetyltransferase 8 increases expression EXP nimesulide results in increased expression of NAT8 mRNA CTD PMID:24136188 NCBI chr 4:117,525,963...117,527,443 JBrowse link
G Ndrg2 NDRG family member 2 decreases expression EXP nimesulide results in decreased expression of NDRG2 mRNA CTD PMID:24136188 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP nimesulide results in increased expression of NDUFA5 mRNA CTD PMID:24136188 NCBI chr 4:51,590,413...51,598,771
Ensembl chr 4:51,590,413...51,598,771
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP nimesulide results in increased expression of NDUFA7 mRNA CTD PMID:24136188 NCBI chr 7:18,683,553...18,696,332
Ensembl chr 7:18,683,553...18,696,330
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP nimesulide results in increased expression of NDUFAB1 mRNA CTD PMID:24136188 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP nimesulide results in increased expression of NDUFAF4 mRNA CTD PMID:24136188 NCBI chr 5:39,251,370...39,256,542
Ensembl chr 5:39,251,337...39,257,512
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 increases expression EXP nimesulide results in increased expression of NDUFC2 mRNA CTD PMID:24136188 NCBI chr 1:162,369,801...162,376,024
Ensembl chr 1:162,369,801...162,376,023
JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP nimesulide results in decreased expression of NECTIN3 mRNA CTD PMID:24136188 NCBI chr11:57,897,879...57,995,193
Ensembl chr11:57,897,879...57,993,548
JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier increases expression EXP nimesulide results in increased expression of NEDD8 mRNA CTD PMID:24136188 NCBI chr15:34,340,607...34,352,673
Ensembl chr15:34,340,607...34,352,673
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
affects localization
ISO
EXP
Sulfaphenazole affects the reaction [nimesulide affects the localization of NFE2L2 protein]
nimesulide results in decreased expression of NFE2L2 mRNA
NFE2L2 mutant form inhibits the reaction [nimesulide results in increased expression of NQO1]
CTD PMID:20405857 PMID:24136188 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfia nuclear factor I/A decreases expression EXP nimesulide results in decreased expression of NFIA mRNA CTD PMID:24136188 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
JBrowse link
G Nfib nuclear factor I/B decreases expression EXP nimesulide results in decreased expression of NFIB mRNA CTD PMID:24136188 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression EXP nimesulide results in decreased expression of NFIL3 mRNA CTD PMID:24136188 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Ngf nerve growth factor multiple interactions EXP nimesulide inhibits the reaction [NGF protein results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [NGF protein results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [NGF results in increased expression of TAC1 mRNA] CTD PMID:21811393 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nhp2 NHP2 ribonucleoprotein increases expression EXP nimesulide results in increased expression of NHP2 mRNA CTD PMID:24136188 NCBI chr10:34,975,701...34,979,082
Ensembl chr10:34,975,708...34,979,082
JBrowse link
G Nid1 nidogen 1 decreases expression EXP nimesulide results in decreased expression of NID1 mRNA CTD PMID:24136188 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 increases expression EXP nimesulide results in increased expression of NIFK mRNA CTD PMID:24136188 NCBI chr13:34,267,442...34,277,543
Ensembl chr13:34,267,471...34,277,530
JBrowse link
G Nit2 nitrilase family, member 2 decreases expression EXP nimesulide results in decreased expression of NIT2 mRNA CTD PMID:24136188 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP nimesulide results in increased expression of NME1 mRNA CTD PMID:24136188 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression EXP nimesulide results in decreased expression of NNT mRNA CTD PMID:24136188 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
G Nomo1 nodal modulator 1 increases expression EXP nimesulide results in increased expression of NOMO1 mRNA CTD PMID:24136188 NCBI chr 1:102,017,247...102,068,871
Ensembl chr 1:102,017,263...102,068,870
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression EXP nimesulide results in increased expression of NOP56 mRNA CTD PMID:24136188 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression
ISO
EXP
nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]; nimesulide inhibits the reaction [bepafant inhibits the reaction [[Mycoplasma arthritidis mitogen results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]]
nimesulide results in increased expression of NOS2 mRNA; nimesulide results in increased expression of NOS2 protein
nimesulide results in decreased expression of NOS2
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]; Silymarin inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; Silymarin inhibits the reaction [nimesulide results in increased expression of NOS2 protein]
CTD PMID:15135310 PMID:15242784 PMID:15892897 PMID:22107987 PMID:22509279 PMID:22940226 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch2 notch receptor 2 decreases expression EXP nimesulide results in decreased expression of NOTCH2 mRNA CTD PMID:24136188 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 decreases expression EXP nimesulide results in decreased expression of NPC2 mRNA CTD PMID:24136188 NCBI chr 6:108,467,410...108,488,330
Ensembl chr 6:108,467,410...108,488,330
JBrowse link
G Npepl1 aminopeptidase-like 1 increases expression EXP nimesulide results in increased expression of NPEPL1 mRNA CTD PMID:24136188 NCBI chr 3:172,195,115...172,207,685
Ensembl chr 3:172,195,844...172,207,685
JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP nimesulide results in increased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:120,316,048...120,370,089
Ensembl chr 3:120,316,047...120,373,500
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression EXP nimesulide results in increased expression of NPLOC4 mRNA CTD PMID:24136188 NCBI chr10:109,553,518...109,610,087
Ensembl chr10:109,552,649...109,610,030
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO
EXP
NFE2L2 mutant form inhibits the reaction [nimesulide results in increased expression of NQO1]
nimesulide results in increased expression of NQO1 mRNA
CTD PMID:20405857 PMID:24136188 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP nimesulide results in increased expression of NR1D2 mRNA CTD PMID:24136188 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP nimesulide results in decreased expression of NR1H4 mRNA CTD PMID:24136188 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP nimesulide results in decreased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP nimesulide results in decreased expression of NREP mRNA CTD PMID:24136188 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression EXP nimesulide results in decreased expression of NSDHL mRNA CTD PMID:24136188 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component increases expression EXP nimesulide results in increased expression of NSMCE1 mRNA CTD PMID:24136188 NCBI chr 1:196,857,490...196,883,907
Ensembl chr 1:196,857,461...196,884,302
JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 increases expression EXP nimesulide results in increased expression of NSUN2 mRNA CTD PMID:24136188 NCBI chr 1:36,295,650...36,319,906
Ensembl chr 1:36,295,650...36,319,966
JBrowse link
G Nt5e 5' nucleotidase, ecto decreases expression
multiple interactions
EXP
ISO
nimesulide results in decreased expression of NT5E mRNA
NT5E protein affects the reaction [nimesulide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of Nitrites]]
CTD PMID:24136188 PMID:27188793 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Nubp2 nucleotide binding protein 2 increases expression EXP nimesulide results in increased expression of NUBP2 mRNA CTD PMID:24136188 NCBI chr10:14,244,201...14,247,930
Ensembl chr10:14,244,203...14,247,886
JBrowse link
G Nudc nuclear distribution C, dynein complex regulator increases expression EXP nimesulide results in increased expression of NUDC mRNA CTD PMID:24136188 NCBI chr 5:151,754,723...151,768,104
Ensembl chr 5:151,754,716...151,768,123
JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP nimesulide results in increased expression of NUDT4 mRNA CTD PMID:24136188 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
JBrowse link
G Nudt7 nudix hydrolase 7 increases expression EXP nimesulide results in increased expression of NUDT7 mRNA CTD PMID:24136188 NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit increases expression EXP nimesulide results in increased expression of NUS1 mRNA CTD PMID:24136188 NCBI chr20:33,557,052...33,584,011
Ensembl chr20:33,557,052...33,584,010
JBrowse link
G Nutf2 nuclear transport factor 2 increases expression EXP nimesulide results in increased expression of NUTF2 mRNA CTD PMID:24136188 NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
JBrowse link
G Oaf out at first homolog decreases expression EXP nimesulide results in decreased expression of OAF mRNA CTD PMID:24136188 NCBI chr 8:47,511,718...47,529,689
Ensembl chr 8:47,511,719...47,529,689
JBrowse link
G Oat ornithine aminotransferase decreases expression EXP nimesulide results in decreased expression of OAT mRNA CTD PMID:24136188 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Obp3 alpha-2u globulin PGCL4 increases expression EXP nimesulide results in increased expression of OBP3 mRNA CTD PMID:24136188 NCBI chr 5:77,313,357...77,316,875 JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP nimesulide results in increased expression of ODC1 mRNA CTD PMID:24136188 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression
multiple interactions
EXP nimesulide results in increased expression of OGG1 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein]; Silymarin inhibits the reaction [nimesulide results in increased expression of OGG1 protein]
CTD PMID:22509279 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP nimesulide results in increased expression of ORM1 mRNA CTD PMID:24136188 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Osbpl11 oxysterol binding protein-like 11 decreases expression EXP nimesulide results in decreased expression of OSBPL11 mRNA CTD PMID:24136188 NCBI chr11:70,77