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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:deoxyribonucleotide
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Accession:CHEBI:4431 term browser browse the term
Definition:A nucleotide in which the ribose moiety has one or more of its hydroxy groups substituted by hydrogen.
Synonyms:related_synonym: deoxyribonucleotides


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2'-deoxycytosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Deoxycytidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
2'-deoxyguanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial increases abundance
multiple interactions
EXP IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate]
CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
dCTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity
ISO
EXP
DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein
CTD PMID:9586059 NCBI chr 5:88,765,013...88,783,277
Ensembl chr 5:88,764,996...88,783,281
JBrowse link
G Polk polymerase (DNA directed), kappa multiple interactions
affects binding
ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149 PMID:31286773 NCBI chr13:96,480,687...96,542,579
Ensembl chr13:96,480,690...96,542,579
JBrowse link
dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM domain and HD domain, 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 2:157,097,534...157,135,096
Ensembl chr 2:157,097,533...157,135,265
JBrowse link
dTDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale galactose-4-epimerase, UDP affects binding ISO thymidine 5'-diphosphate binds to GALE protein CTD PMID:25526675 NCBI chr 4:135,963,681...135,968,178
Ensembl chr 4:135,963,727...135,968,178
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [thymidine 5'-diphosphate co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 1:43,746,961...43,827,839
Ensembl chr 1:43,746,966...43,827,800
JBrowse link
dTMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Thymidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
dUMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 increases export ISO ABCC5 protein results in increased export of 2'-deoxyuridylic acid CTD PMID:15897250 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid CTD PMID:29258758 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21746
    role 21724
      application 21226
        solvent 17569
          phosphoric acid 8023
            phosphoric acid derivative 7688
              organic phosphate 7687
                nucleoside phosphate 1717
                  nucleotide 1716
                    deoxyribonucleotide 8
                      2'-deoxyribonucleotide + 8
                      3'-deoxyribonucleotide + 0
                      5'-deoxyribonucleotide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21746
    subatomic particle 21732
      composite particle 21732
        hadron 21732
          baryon 21732
            nucleon 21732
              atomic nucleus 21732
                atom 21732
                  main group element atom 21647
                    p-block element atom 21647
                      chalcogen 20779
                        oxygen atom 20756
                          oxygen molecular entity 20756
                            hydroxides 20182
                              oxoacid 19495
                                pnictogen oxoacid 10425
                                  phosphorus oxoacid 9290
                                    phosphoric acids 8023
                                      phosphoric acid 8023
                                        phosphoric acid derivative 7688
                                          phosphate 7688
                                            organic phosphate 7687
                                              carbohydrate phosphate 1729
                                                phospho sugar 1652
                                                  aldose phosphate 1650
                                                    aldopentose phosphate 1644
                                                      deoxyaldopentose phosphate 9
                                                        deoxyribonucleotide 8
                                                          2'-deoxyribonucleotide + 8
                                                          3'-deoxyribonucleotide + 0
                                                          5'-deoxyribonucleotide + 0
paths to the root