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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:menaquinone-7
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Accession:CHEBI:44245 term browser browse the term
Definition:A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
Synonyms:exact_synonym: 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione
 related_synonym: (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosahept-aenyl)-3-methyl-1,4-naphthoquinone;   (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;   Formula=C46H64O2;   InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+;   InChIKey=RAKQPZMEYJZGPI-LJWNYQGCSA-N;   MK-7;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC1=C(C)C(=O)c2ccccc2C1=O;   vitamin K2(35);   vitamin MK 7
 xref: AGR:IND606538604;   AGR:IND606948745;   AGR:IND607052678;   Beilstein:2343160;   CAS:2124-57-4;   DrugBank:DB13075
 xref_mesh: MESH:C062629
 xref: MetaCyc:CPD-9718;   PDBeChem:MQ7;   PMID:13946233;   PMID:2153497;   PMID:24173914;   PMID:24174310;   PMID:24296867;   PMID:24453233;   PMID:31054684;   PMID:31152205;   PMID:31250633;   PMID:31579595;   PMID:32009201;   PMID:32109677;   PMID:32737601;   PMID:32952745;   PMID:33030563;   PMID:33090426;   PMID:33133563;   PMID:33233274;   PMID:33502649;   PMID:33574019;   PMID:33585456;   PMID:33664429;   PMID:33755417;   PMID:34029943;   PMID:34115006;   Reaxys:2343160


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menaquinone-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases carboxylation		 ISO Warfarin inhibits the reaction [vitamin MK 7 results in increased carboxylation of BGLAP protein] CTD PMID:31173816 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO vitamin MK 7 results in increased expression of TNFRSF11B mRNA CTD PMID:31173816 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          cofactor 15798
            menaquinone-7 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      ketone 16957
                                        cyclic ketone 15522
                                          quinone 8385
                                            p-quinones 8294
                                              prenylquinone 113
                                                prenylnaphthoquinone 30
                                                  menaquinones 30
                                                    menaquinone 30
                                                      menaquinone-7 2
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