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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:menaquinone-7
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Accession:CHEBI:44245 term browser browse the term
Definition:A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
Synonyms:exact_synonym: 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione
 related_synonym: (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosahept-aenyl)-3-methyl-1,4-naphthoquinone;   (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;   Formula=C46H64O2;   InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+;   InChIKey=RAKQPZMEYJZGPI-LJWNYQGCSA-N;   MK-7;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC1=C(C)C(=O)c2ccccc2C1=O;   vitamin K2(35);   vitamin MK 7
 xref: AGR:IND606538604;   AGR:IND606948745;   AGR:IND607052678;   CAS:2124-57-4;   DrugBank:DB13075
 xref_mesh: MESH:C062629
 xref: MetaCyc:CPD-9718;   PDBeChem:MQ7;   PMID:13946233;   PMID:2153497;   PMID:24173914;   PMID:24174310;   PMID:24296867;   PMID:24453233;   PMID:31054684;   PMID:31152205;   PMID:31250633;   PMID:31579595;   PMID:32009201;   PMID:32109677;   PMID:32737601;   PMID:32952745;   PMID:33030563;   PMID:33090426;   PMID:33133563;   PMID:33233274;   PMID:33502649;   PMID:33574019;   PMID:33585456;   PMID:33664429;   PMID:33755417;   PMID:34029943;   PMID:34115006;   Reaxys:2343160



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menaquinone-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases carboxylation
ISO Warfarin inhibits the reaction [menaquinone 7 results in increased carboxylation of BGLAP protein] CTD PMID:31173816 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO menaquinone 7 results in increased expression of TNFRSF11B mRNA CTD PMID:31173816 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        biochemical role 20264
          cofactor 16931
            menaquinone-7 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbonyl compound 19440
                                    ketone 17484
                                      cyclic ketone 16126
                                        quinone 9948
                                          p-quinones 8612
                                            prenylquinone 157
                                              prenylnaphthoquinone 30
                                                menaquinones 30
                                                  menaquinone 30
                                                    menaquinone-7 2
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