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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:menaquinone-7
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Accession:CHEBI:44245 term browser browse the term
Definition:A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
Synonyms:exact_synonym: 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione
 related_synonym: (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosahept-aenyl)-3-methyl-1,4-naphthoquinone;   (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;   Formula=C46H64O2;   InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+;   InChIKey=RAKQPZMEYJZGPI-LJWNYQGCSA-N;   MK-7;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC1=C(C)C(=O)c2ccccc2C1=O;   vitamin K2(35)
 xref: Beilstein:2343160;   CAS:2124-57-4
 xref_mesh: MESH:C062629
 xref: MetaCyc:CPD-9718;   PDBeChem:MQ7;   PMID:24173914;   PMID:24174310;   PMID:24296867;   PMID:24453233;   Reaxys:2343160

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menaquinone-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases carboxylation		 ISO Warfarin inhibits the reaction [vitamin MK 7 results in increased carboxylation of BGLAP protein] CTD PMID:31173816 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO vitamin MK 7 results in increased expression of TNFRSF11B mRNA CTD PMID:31173816 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      biological role 19833
        biochemical role 19370
          metabolite 19350
            prokaryotic metabolite 18441
              bacterial metabolite 18441
                Mycoplasma genitalium metabolite 7677
                  menaquinone-7 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic group 18580
                              organic divalent group 18571
                                organodiyl group 18571
                                  carbonyl group 18479
                                    carbonyl compound 18479
                                      ketone 16222
                                        cyclic ketone 13938
                                          quinone 8388
                                            p-quinones 8292
                                              prenylquinone 123
                                                prenylnaphthoquinone 56
                                                  menaquinones 56
                                                    menaquinone 56
                                                      menaquinone-7 2
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