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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-butylbenzenesulfonamide
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Accession:CHEBI:44237 term browser browse the term
Definition:A sulfonamide that is benzenesulfonamide substituted by a butyl group at the nitrogen atom. It has been isolated from the plant Prunus africana and has been shown to exhibit antiandrogenic activity.
Synonyms:related_synonym: Benzenesulfonic acid butyl amide;   Dellatol BBS;   Formula=C10H15NO2S;   InChI=1S/C10H15NO2S/c1-2-3-9-11-14(12,13)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3;   InChIKey=IPRJXAGUEGOFGG-UHFFFAOYSA-N;   N-(n-Butyl)benzenesulfonamide;   Plastomoll BMB;   SMILES=CCCCNS(=O)(=O)c1ccccc1
 xref: CAS:3622-84-2
 xref_mesh: MESH:C065565
 xref: PDBeChem:NBB;   PMID:16783690;   PMID:17369196;   PMID:22789816;   PMID:22824510;   PMID:8512189;   Patent:CA2596618;   Patent:WO2006081994;   Reaxys:2725965


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N-butylbenzenesulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 decreases expression EXP N-butylbenzenesulfonamide results in decreased expression of AIF1 mRNA CTD PMID:22824510 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        aetiopathogenetic role 18937
          neurotoxin 17550
            N-butylbenzenesulfonamide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                chalcogen oxoacid 11482
                                  sulfur oxoacid 11085
                                    sulfonic acid 7333
                                      sulfonic acid derivative 7333
                                        sulfonamide 3168
                                          N-butylbenzenesulfonamide 4
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